LOCUS       NZ_CP019464            15601 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete
            sequence.
ACCESSION   NZ_CP019464
VERSION     NZ_CP019464.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 15601)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 15601)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 15601
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019464.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..15601
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     protocluster    1..15601
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:15601](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..15601)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(join(3331..15601,1..>3248))
                     /locus_tag="BV401_RS45680"
                     /old_locus_tag="BV401_41190"
                     /pseudo=""
     CDS             complement(join(3331..15601,1..>3248))
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (2-30). E-value:
                     3.4e-11. Score: 34.5. Matches aSDomain:
                     nrpspksdomains_BV401_RS45680_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (34-460). E-value:
                     1.7e-183. Score: 602.3. Matches aSDomain:
                     nrpspksdomains_BV401_RS45680_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (565-863). E-value: 1.1e-112.
                     Score: 368.2. Matches aSDomain:
                     nrpspksdomains_BV401_RS45680_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (930-1096). E-value: 2.2e-55.
                     Score: 179.5. Matches aSDomain:
                     nrpspksdomains_BV401_RS45680_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057311.1"
                     /locus_tag="BV401_RS45680"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="BV401_41190"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="mod_KS (E-value: 1.6e-231, bitscore:
                     754.6, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.8e-95, bitscore:
                     303.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.9e-114, bitscore:
                     368.2, seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSETKLRDYLKRATASLHETRQELKELKDRDREPIAIVGMGCRYP
                     GGVESPEDLWELVASGTDAVSTFPVDRGWDEDLYDPDPEKPGKSYTREGGFLHNANGFD
                     ASFFGMSPREALATDPQQRLLLETSWEALERAGIDPASARGSRTGVFVGVMYNDYGSRI
                     QSIPEGLEGHLGNGSAGSVASGRISYTFGFEGPAVTVDTACSSSLVALQLAVQALHKGD
                     CSLALAGGVAMMATPGVFIEFSRLRGLAVDGRCKSFSNAADGTGWSEGAGVLLLERLSD
                     AQRNGHQVLAVVRGAAVNQDGASSRLTAPNGPSQQRVIRDALRNAGLSAADVDAVEAHG
                     TGTPLGDPIEAQALLATYGKERAGADRPLWLGSFKSNVGHTQAAAGVGGVIKMVMAMRH
                     GVLPKTLHVEEPSEHVDWSAGAVSLLTESTPWPETGEPRRAGVSSFGVSGTNAHVILEQ
                     APEAEAAGDAEPEVADGPVAWVVSGHGAEGLRAQAERLRAYVAGRSELGAADVARSLVM
                     TRSVLDHRAVLVGRDRDELLSGLGAVAEKSALPGVVVGESAPPGRSVFVFPGQGAQWVG
                     MAVGLLESSPVFAEAVGECEAALSAYVDWSLTGVLRGVEGAPGFDRVDVVQPVLFAVMV
                     SLARLWRSVGVEPDAVMGHSQGEIAAACVAGGLSLEDAAKVVALRSQAIAVGLAGRGGM
                     VSVGLSAEQAEERIARWGGAISVAAVNGPGSVVVAGDPDALDEMVAELEGEEVRVRRVP
                     VDYASHSAHVEGIREELLRVLADLQPRSSEVPFYSTVTGELVDTAQLDAEYWYRNLRQT
                     VELESTTRTLLDAGHTVFIEVSPHPVLTLPVQQTVEAAESRAVVVGTLRRDEGGAERFL
                     TSAAELHVSGARVDWQKVFAGHGAHRVELPTYAFQHERFWLDAPAGVGDVGSVGLGSLG
                     HPLLGAVVSLASGGGVLLSGRLSLATHEWLADHAVHGVMLLPGTAFVELVVRAGDQVGC
                     GRVEELVIEAPLIVPEKGGVHLQVEVGEADASGFREVSVYSREEADGDGAAWVRHAHGV
                     LGSAVPSSETQYDFGVWPPVGAELVDVSGEYVRAAGERVGVWACFSGVEACVAA"
     source          1..15601
                     /collection_date="1998-01-01"
                     /country="China:Yunnan"
                     /culture_collection="CGMCC:0516"
                     /db_xref="taxon:75293"
                     /isolation_source="soil sample"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces autolyticus"
                     /plasmid="unnamed7"
                     /strain="CGMCC0516"
     cand_cluster    1..15601
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     misc_feature    2921..2937
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.48"
                     /tool="antismash"
     aSDomain        complement(3349..3846)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45680_PKS_DH.1"
                     /evalue="2.20E-55"
                     /label="BV401_RS45680_PKS_DH.1"
                     /locus_tag="BV401_RS45680"
                     /protein_end="1096"
                     /protein_start="930"
                     /score="179.5"
                     /tool="antismash"
                     /translation="HPLLGAVVSLASGGGVLLSGRLSLATHEWLADHAVHGVMLLPGTA
                     FVELVVRAGDQVGCGRVEELVIEAPLIVPEKGGVHLQVEVGEADASGFREVSVYSREEA
                     DGDGAAWVRHAHGVLGSAVPSSETQYDFGVWPPVGAELVDVSGEYVRAAGERVGVWACF
                     SGV"
     aSModule        complement(3349..6534)
                     /domains="nrpspksdomains_BV401_RS45680_PKS_KS.1"
                     /domains="nrpspksdomains_BV401_RS45680_PKS_AT.1"
                     /domains="nrpspksdomains_BV401_RS45680_PKS_DH.1"
                     /incomplete
                     /locus_tags="BV401_RS45680"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(3688..3762)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0013"
                     /evalue="1.10E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="BV401_RS45680"
                     /protein_end="983"
                     /protein_start="958"
                     /score="30.8"
                     /tool="antismash"
                     /translation="WLADHAVHGVMLLPGTAFVELVVRA"
     CDS_motif       complement(3940..3972)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0012"
                     /evalue="5.40E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BV401_RS45680"
                     /protein_end="899"
                     /protein_start="888"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="VFAGHGAHRVE"
     aSDomain        complement(4048..4941)
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45680_PKS_AT.1"
                     /evalue="1.10E-112"
                     /label="BV401_RS45680_PKS_AT.1"
                     /locus_tag="BV401_RS45680"
                     /protein_end="863"
                     /protein_start="565"
                     /score="368.2"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWVGMAVGLLESSPVFAEAVGECEAALSAYVDWSLTGV
                     LRGVEGAPGFDRVDVVQPVLFAVMVSLARLWRSVGVEPDAVMGHSQGEIAAACVAGGLS
                     LEDAAKVVALRSQAIAVGLAGRGGMVSVGLSAEQAEERIARWGGAISVAAVNGPGSVVV
                     AGDPDALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIREELLRVLADLQPRSSEVPFY
                     STVTGELVDTAQLDAEYWYRNLRQTVELESTTRTLLDAGHTVFIEVSPHPVLTLPVQQT
                     VEAAESRAVVVGTLRRD"
     CDS_motif       complement(4120..4149)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0011"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="BV401_RS45680"
                     /protein_end="839"
                     /protein_start="829"
                     /score="10.7"
                     /tool="antismash"
                     /translation="FIEVSPHPVL"
     CDS_motif       complement(4195..4239)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0010"
                     /evalue="4.80E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="BV401_RS45680"
                     /protein_end="814"
                     /protein_start="799"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRQTVE"
     misc_feature    4284..4299
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.02"
                     /tool="antismash"
     CDS_motif       complement(4345..4377)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0009"
                     /evalue="4.00E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="BV401_RS45680"
                     /protein_end="764"
                     /protein_start="753"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VDYASHSAHVE"
     CDS_motif       complement(4444..4485)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0008"
                     /evalue="9.60E-03"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="BV401_RS45680"
                     /protein_end="731"
                     /protein_start="717"
                     /score="8.6"
                     /tool="antismash"
                     /translation="AAVNGPGSVVVAGD"
     CDS_motif       complement(4594..4704)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0007"
                     /evalue="1.00E-19"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="BV401_RS45680"
                     /protein_end="681"
                     /protein_start="644"
                     /score="62.2"
                     /tool="antismash"
                     /translation="GVEPDAVMGHSQGEIAAACVAGGLSLEDAAKVVALRS"
     CDS_motif       complement(4708..4776)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0006"
                     /evalue="2.10E-12"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="BV401_RS45680"
                     /protein_end="643"
                     /protein_start="620"
                     /score="38.6"
                     /tool="antismash"
                     /translation="DRVDVVQPVLFAVMVSLARLWRS"
     CDS_motif       complement(4891..4947)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0005"
                     /evalue="4.30E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BV401_RS45680"
                     /protein_end="582"
                     /protein_start="563"
                     /score="28.0"
                     /tool="antismash"
                     /translation="VFVFPGQGAQWVGMAVGLL"
     misc_feature    5139..5153
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     CDS_motif       complement(5188..5217)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0004"
                     /evalue="2.20E+01"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="BV401_RS45680"
                     /protein_end="483"
                     /protein_start="473"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="DGPVAWVVSG"
     aSDomain        complement(5257..6534)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45680_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.70E-183"
                     /label="BV401_RS45680_PKS_KS.1"
                     /locus_tag="BV401_RS45680"
                     /protein_end="460"
                     /protein_start="34"
                     /score="602.3"
                     /tool="antismash"
                     /translation="IAIVGMGCRYPGGVESPEDLWELVASGTDAVSTFPVDRGWDEDLY
                     DPDPEKPGKSYTREGGFLHNANGFDASFFGMSPREALATDPQQRLLLETSWEALERAGI
                     DPASARGSRTGVFVGVMYNDYGSRIQSIPEGLEGHLGNGSAGSVASGRISYTFGFEGPA
                     VTVDTACSSSLVALQLAVQALHKGDCSLALAGGVAMMATPGVFIEFSRLRGLAVDGRCK
                     SFSNAADGTGWSEGAGVLLLERLSDAQRNGHQVLAVVRGAAVNQDGASSRLTAPNGPSQ
                     QRVIRDALRNAGLSAADVDAVEAHGTGTPLGDPIEAQALLATYGKERAGADRPLWLGSF
                     KSNVGHTQAAAGVGGVIKMVMAMRHGVLPKTLHVEEPSEHVDWSAGAVSLLTESTPWPE
                     TGEPRRAGVSSFGVSGTNAHVILEQAP"
     CDS_motif       complement(5479..5523)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0003"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="BV401_RS45680"
                     /protein_end="386"
                     /protein_start="371"
                     /score="10.6"
                     /tool="antismash"
                     /translation="GSFKSNVGHTQAAAG"
     CDS_motif       complement(5587..5631)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0002"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BV401_RS45680"
                     /protein_end="350"
                     /protein_start="335"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VEAHGTGTPLGDPIE"
     misc_feature    5716..5730
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     CDS_motif       complement(6007..6054)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45680_0001"
                     /evalue="5.00E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="BV401_RS45680"
                     /protein_end="210"
                     /protein_start="194"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     misc_feature    complement(6310..6325)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     aSDomain        complement(6547..6630)
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45680_PKS_Docking_Nterm.
                     1"
                     /evalue="3.40E-11"
                     /label="BV401_RS45680_PKS_Docking_Nterm.1"
                     /locus_tag="BV401_RS45680"
                     /protein_end="30"
                     /protein_start="2"
                     /score="34.5"
                     /tool="antismash"
                     /translation="ETKLRDYLKRATASLHETRQELKELKDR"
     misc_feature    7067..7082
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(14316..14330)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.09"
                     /tool="antismash"
     misc_feature    14542..14556
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    complement(15222..15235)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
ORIGIN
        1 gcagcccgca catactcacc cgacacatca accaactcag cccccaccgg aggccacaca
       61 ccaaagtcgt actgtgtctc ggagctgggc acggccgaac cgagcacacc atgggcatgc
      121 cgcacccatg ccgcgccatc gccgtccgcc tcctcccgcg agtacacgct cacctcacgg
      181 aagccggaag cgtcggcctc ccccacctca acctggaggt gtacgccacc cttctcgggc
      241 acgatcagcg gcgcttcgat gaccagttcc tcgacccggc cgcagccgac ctgatcgccc
      301 gcccgtacca ccagctcgac gaacgccgtc cccggcagca gcatcacccc gtgtacggcg
      361 tgatccgcca gccactcatg cgtggccaac gacaaccgcc cactcagcag caccccgcca
      421 ccactcgcca acgacaccac cgcacccagc aacggatgcc ccagcgaacc caaccccacc
      481 gaacccacat cacccacacc ggcgggagcg tcaagccaga agcgctcgtg ctggaaggcg
      541 taggtcggca attcaacgcg gtgggcgccg tgtccggcga acaccttttg ccagtcaacg
      601 cgcgccccgc tgacgtgaag ctcagcggcg gaggtcagga accgctcggc cccgccctca
      661 tcgcgccgta gtgtccccac gaccacggcc cgcgactcag cggcctcaac tgtctgctgc
      721 accggaaggg tcagcaccgg atgcgggctg acctcgatga acacggtgtg gcccgcgtcg
      781 agcagcgtgc gagtcgtgga ctccagctca accgtctgcc gcaggttccg gtaccagtac
      841 tcggcgtcca gctgagccgt gtccaccagc tcaccggtca ccgtcgagta gaacggcacc
      901 tccgaggacc gcggctgaag gtccgccaga accctcagca gctcctcacg aatcccctcc
      961 acatgcgcgg aatgcgaggc atagtccacc ggaacccgac ggacccgcac ctcctcaccc
     1021 tccagctccg caaccatctc atccagcgcg tccgggtcac cggccaccac gaccgaaccc
     1081 ggaccattga ccgccgccac cgaaatcgcc ccaccccacc gggcgatacg ctcctccgcc
     1141 tgctccgcgg acaacccgac cgacaccatg ccaccacgac cagcaagccc caccgcgatc
     1201 gcctgcgacc gcaacgccac caccttcgcg gcatcctcca gcgacaaccc acccgccaca
     1261 cacgccgcag caatctcacc ctgactatga cccatcaccg catccggctc cacacccacc
     1321 gaacgccaca accgcgccaa cgacaccatc accgcaaaca acaccggctg caccacatcc
     1381 acccgatcaa aaccaggcgc accctcaaca ccacgcaaca cacccgtcaa cgaccagtcc
     1441 acatacgccg acagcgccgc ctcacactca ccaaccgcct ccgcgaacac cggcgaggac
     1501 tccaacaacc ccactgccat acccacccac tgcgccccct gccccgggaa cacaaacacc
     1561 gaacggccgg gaggcgcgct ctcgcccacc accacgcccg gaagagcgga cttctccgcg
     1621 acggcgccca gaccggacag caactcgtcc cggtcccggc ccaccagcac cgcgcggtga
     1681 tccagcaccg accgggtcat caccagcgac cgcgccacat cggcggcgcc cagctccgaa
     1741 cgcccggcca cgtacgcccg cagccgctcg gcctgggccc gcagcccctc ggcaccgtgg
     1801 cccgacacca cccaggccac cggaccgtcg gcgacctcgg gctcagcgtc cccggccgcc
     1861 tcggcctccg gggcctgctc caggatcaca tgcgcgttcg tcccgctcac accgaacgag
     1921 gacacaccgg ccctgcgcgg ctcacccgtc tccggccacg gggtcgactc ggtcagcagc
     1981 gacaccgccc ccgccgacca gtccacgtgc tccgacggct cctctacatg cagggtcttc
     2041 ggcagcacac cgtgccgcat cgccatcacc atcttgatga cgccacccac acccgcggcc
     2101 gcctgcgtgt gacccacgtt cgacttgaac gagcccagcc acaacggccg atcggctccg
     2161 gcgcgctcct tgccgtaggt ggccagcagc gcctgtgcct cgatggggtc gcccagcggt
     2221 gttccggtgc cgtgtgcctc caccgcgtcg acatccgccg cggacaggcc ggcgttgcgc
     2281 agcgcgtcgc ggatcacccg ctgctgcgag gggccgttgg gagccgtcag ccggctgctc
     2341 gccccgtcct ggttcacggc ggcgccccgt accacggcca gcacctggtg tccgttgcgc
     2401 tgggcgtcgg acagtcgctc cagcagcagc acaccggcgc cctcggacca tccggtgccg
     2461 tcggccgcgt tcgagaacga cttgcagcgt ccgtccacgg cgagtccgcg caaccggctg
     2521 aactcgatga acacccctgg tgtcgccatc atggccacgc caccggcgag cgcgagcgag
     2581 cagtcgccct tgtggagcgc ctggacggcc agttggagcg ccacgagcga cgaggagcat
     2641 gccgtgtcca cggtcacggc ggggccttcg aagccgaagg tgtaggagat acggccggag
     2701 gcgacgcttc cggcgctgcc gttgccgagg tggccttcga ggccctcggg tatggactgg
     2761 atgcgggagc cgtagtcgtt gtacatcacg ccgacgaaca cgccggtgcg gctgccacgc
     2821 gcggacgccg ggtcgatgcc cgcgcgctcc agcgcctccc atgaggtctc cagcagcagc
     2881 cgctgctgtg ggtcggtcgc cagcgcctca cgcggactca tgccgaagaa ggaggcgtcg
     2941 aagccgttcg cgttgtgcag gaacccgccc tcacgcgtat agctcttgcc cggcttctcc
     3001 gggtcggggt cgtacaggtc ctcgtcccac ccacggtcca cggggaaggt ggacaccgcg
     3061 tcggtgcccg aggcgaccag ctcccacagg tcttcgggcg actccactcc gccgggatac
     3121 ctgcacccca tgccgacgat cgcgatgggt tcccggtccc tgtccttgag ttccttcagc
     3181 tcttgacgag tttcgtgcag gctggccgtc gcgcgcttga ggtagtcgcg cagcttggtc
     3241 tcactcaccg cttcttgtca ctcctctgag caccccggac aggggtggaa agccttcggc
     3301 cggtaacttc cggggacggg ggcgtccgcg tcacgagagc tcctcgtcga ggaagtcgaa
     3361 gatctcgtcg tcggtggccg actcgaactt gtcggcggcg acgaccccac cgttcgcggt
     3421 ctccgtctgc tgccccgcgg tcagcttcgc cagcacctgc tgcaagcgcg aggtgagacg
     3481 tgccgtggcg gcttcgtccg ccaccacctc ggcgaaggag cgctccagct tctccagctc
     3541 cgacagaacc ggcagcacca gcgatgcgtc cggctcttcc gcgacgagct cctgcgccag
     3601 gtagccggcc agcgccctgg acgtcgtgta gtcgaacagc agggtggcgg ggagccgcag
     3661 accggtcacc gtgcccagct ggttgcgcag tccgaccgcg gtcagcgagt cgaagcccag
     3721 ctcgaggaag ccacggtcgg gggcgatcat gcgggggctg tcgtggccca gcgccatggc
     3781 cgcgtgctcc gtgaccagtt cgaggagcgc ctgctgccgg gcggcggggt tcatcgagcc
     3841 gatccggcgg cgcagttcgg cggggtcggc gccggatccg cccgtggacg ccttcgcggg
     3901 gccgcgccgg gccgtggtcc ggatgatgcc ccgcagcagc gccgggatcg gcccgtcctg
     3961 ggctcgccac gccgaggcgt tgagccgtgc cgggaccaga gtggccgcgt cgatgccgcg
     4021 ggcggcgtcg aacagggcca gtgcctcctc ggaggacatc ggggtcacgc cttcgcgggc
     4081 gaggcgccgc atatgggcct cgtccagctt gcccgtcata ccgctgcgct cctcccacag
     4141 gccccaggcc agcgactggg cgggaaggcc ctcggcccgg cgccggtggg cgaacgcgtc
     4201 caggaaggcg ttggcggccg cgtagttggc ctggccggtg ccgccgaggg ttccggagag
     4261 cgaggagaag agcacgaacg cggacaggtc gagaccggcg gtcagctcgt gcagattgag
     4321 caccgcgtcc accttgggcc gcagcacacg gtccacccgc tcgggcgtga gggcttcgac
     4381 gacgccgtcg tccagcactc cggcggtgtg caccacggcg gtgagcgggt gttcgtccgg
     4441 cagggaggcc agaagcgcgg cgagggagtc gcggtcggcg gtgtcacagg cggcgaccac
     4501 ggcgtgggcg ccgaggtccg tcagctccgt ccgcagttcg gccgcgccgt ccgcggcgag
     4561 gccgcggcgg ctgaccagca cgaggtggcg gacgccgtgc tcgccgacga ggtgcttggc
     4621 gaccaggccg ccgaggccgg atgccgcccc ggtgaccagg acggtgccct gcgggtccca
     4681 ggtgacgccg gtcgtgaccg accgtgcgtc gccctgctcg gacgcgctgc catgcgccgc
     4741 cacccgggcc agccggccga ccaggaccgt gccgttccgg accacgatct gtggttcgtc
     4801 ggtggtgagc gccgccggga ggatccggcg cgagccttcc ctgtcgtcca ggtcggccag
     4861 gacgaaccgg ccggggttct cggactgggc cgagcgcacc aggccccaga cggccgcact
     4921 ggcggggtcg gccacatcgg tgtcatcgcc cgcggcgatg gccccccggg tgaggaagac
     4981 cagccgggag ccgccgaggc ggttgtcggc cagccagctc ttgagcaggt cgagggcgtg
     5041 gtggccggct tcccgtaccg cctccgccag ttcccgcgtc cggccggtgc gggacacgtt
     5101 cgcggcgagt acgacgtcgg gcgcggtcgc gcccgcgtcg atggcctcgg ccagggccgc
     5161 gaggtccggg taggtgtcca cggtgacatc ggccgatccg agggcgccgg tcagctcggc
     5221 ccggtcgggt ccgacgagcg cccagcgccc ggcggccgcg ccgctcgtct ccggggcggt
     5281 cggcacccag tcgacctggt acagcgactc gtgcggctgg gcggagttga cctgctccgg
     5341 ggccacgggc cgcagtacga gcgagtcgac cgaggcgacg agcgcgccgg agacgtcggt
     5401 gacgtgcagg gagaccgtgt cctcgccgac gctggtcagc cgcacccgca gcgcggacgc
     5461 gccgcttgcg tggagggtca ccccgttcca cgagaacggg agggtgctgc cgtcgctgcc
     5521 ggacggcttg aacgccacgg tgtgcagcga ggcgtcgagc agcgccgggt ggagaccgta
     5581 gcgcgcggcc tcgccctcct gtgcctcggg caggtcgacc tcggcgaaga cctcgtcgcc
     5641 acggcgccag gcggcgcgca gcccctggaa ggccgggccg taggcgaagc cgacgtcgat
     5701 gaaccggtcg tagagatcgg ccacgtcgat ggcctccgca tccgcgggcg gccacacggc
     5761 gaagtcggcg gccacggact ccggtgccgt ggtggacagg tccctgctga gcaggccggt
     5821 cgtatggcgc gtccaggggt cgtccggctg ggcgtcctcg ggcctggagt acagattgag
     5881 cgaacgggcg ccggactcgt ccggctcgcc cacggcgagc tggatctgga ccgcgccgcg
     5941 tacgggcagg accaacggca tttcgatggt cagttcctcc acccgctcgt agcccacctg
     6001 ctcggcggcg cgcagggcca gttccacgaa ggccgtgccg gggaagagca cggtgtccgc
     6061 gaaggcgtgg tcggccagcc acggctgggt ggcgaccgac aggcgcccgg tgaacaggta
     6121 ggtgtcggtg tcggccaggg cgacggcggc gcccaggagc ggatggtcgg gcgagtccag
     6181 gcccgccgat gtcacatctc cactggcggc cggcgcggct tcgagccagt agcgctgccg
     6241 ctggaaggcg taggtgggca gctccacccg ctgggcgcca cgcccggcga acaccgcgtc
     6301 ccacttcacc gtgacgccgt gcacatggag ttcggccagc gccatggtca gcgactgaag
     6361 ctcgggccgg tccttgcgca gtgcgggcac gagggcggga gccaccgcgc caccgggttc
     6421 tgcggccgtc aggcagtcct gcgccatcgc ggtgagcaca ccgtccgggc ccacctcgac
     6481 gaacgaggtc acgcccaggt tctccagggt ccttaccccg tccgcgaacc gcacggcctc
     6541 gcgcacatgc cggacccagt actccggcga gcacacctcg tccgcgtcgg ccggggcgcc
     6601 ggtgacgttg gacaccaggg agatggtcgg cggggcgaac aacagcccct cgacaacctt
     6661 ccggaagtca ccgagcacac cgtccatgcg cggggagtgg aaggcgtggc tgacgcgcag
     6721 gcggcgtgtc ttacggccct cccgctccca ctgtccggcg atctccagca cggcgggctc
     6781 gtcgcccgcg atgaccacgg cggtggggcc gttgatggcc gcgatgctca cctcggcctc
     6841 tcgaccggcc agcgacgcgg cgatctcctc ctcgggcgcc tggacggcca ccatcgcgcc
     6901 gccttcgggc agcgcctgca tcagccggcc acgggccgcc accagggcgc acgcgtcctc
     6961 cagggagaac accccggcca catgggcggc ggcgacctca ccgatggagt ggccgatcag
     7021 cacatccggg gtgacacccc agtgctccag cagccggaac agcgccacct cgatggcgaa
     7081 cagcgcgggc tgggtgaacg ccgtctggtt cagcaactcg gcgtcggcac tgccctcgac
     7141 cgcgaacatc acctcggtca gcggccggtc gagcagcaca tcgaggtagg cgcacacctc
     7201 gtccagcgcc tgggcgaaca ccgggaaggc gtcgtacagc tcccggccca tgcccagccg
     7261 ctgcgcgccc tggcccgaga acaggaacgc cgtcttgtgc tcggcccgtg ccacgccctg
     7321 gatcagcgtg gccgcgttcc cgcccgccgc caacgcttcg agcccggagc ggaactgcgc
     7381 cgggtcctcc gcgaccacag cggcgcggta gggcagggcg gaacgggtgg tcgccagcga
     7441 gtagccgatg tcggcgacat caccggcccg cgcggtgcgc acaccgtcga actcgcgcag
     7501 ccgcccggcc tgagcgctca gcgcatcggc gttgctgccc gagagcagcc agggaaccac
     7561 cgtgagaccc gcgggcgaac cggtggcctc gccacccgtc tccggcgacg gcgactcaac
     7621 ggggtcggcc gcctcgatga tcgtgtgcgc gttggtgccg ctgatcccga aggacgacac
     7681 ggccgcccgg cgcgggcggt ccgtctccgg ccacgcggtc gcctcgttca gcagcgacac
     7741 ggcgccactg gtccagtcga tatgcggcga gggctcgtcc gcgtggagcg tcttcggcag
     7801 cacgccctcg cgcatggcca tcaccatctt gatgacaccc gcgacaccgg ccgcggcctg
     7861 cgtgtgcccg atgttcgact tgatcgagcc cagccacagc ggctggtcct cggaacgcgc
     7921 ctggccgtac gtggccagca gcgcctgcgc ctcgatcggg tcacccagcg aggtgcccgt
     7981 gccatgtgcc tccaccgcgt ccacatcggc ggccgacaga cccgcgtttt caagggcctt
     8041 gccgatcaca cgctgctgcg acgggccgtt cggcgccgtc agaccgttgg acgcgccgtc
     8101 ctggttgatc gccgaacccc ggacgacggc cagcaccttg tggccgcggc gccgggcgtc
     8161 cgacagccgc tccaccagca gcagacccac accctcggac cagccggtgc catcggcctc
     8221 ggcggagaac gccttgcacc gtccgtccgg cgacagcaca cgctgggcgc tgaactcgac
     8281 gaacgtgccc ggcgtggcca tgatcgtcac accgccggcc agcgccatgt cgcactcgcc
     8341 ctggcgcagc gactggcagg ccaggtgcag ggcgaccagc gacgacgaac acgcggtgtc
     8401 caccgtcacg gccgggccct cgaagccgaa ggtgtaggag aggcggccgg aggcgacgct
     8461 ggacgcgctg ccgagtccga ggtagccctg cacaccgtcc ggcgcgctga tcgcccggcc
     8521 gctgtagtcc tggtagttcg agccgatgaa gacacccgcc tggctgccgc gcaacgccgc
     8581 cgggtcgatt ccggcccgct cgaacgcctc ccaggacgtc tccagcagca gccgctgctg
     8641 ggggtccatg gccagggcct cacgcggtga gatgccgaag aagtccgggt cgaagtcgga
     8701 gacgttgtcc aggaacccgc cggtgagcgc gtaggtcttg cccggcttgt cggggtcggg
     8761 gtcgtagagc ccgtcgaggt cccagccacg gtcgtcgggg aacccggaga tcgtgtcgac
     8821 tccggcgttc accacgtccc acagctgttc aggggtccgc acaccgcccg ggaagcggca
     8881 gctcatcgcc acgatcgcga tgggctcgtc gaaggagtcc gatcgggtcg gcgtgacctc
     8941 ggcggcgccg ccttcctcgg tgccgaacat ctcgccgttc aggaaccgcg ccagcaccgt
     9001 gggcgtgggg tagtcgaaga ccaggctgac cggcagccgc agcccggtcg ccgcgccgat
     9061 ccgattgcgc agttcaacgg cggtcagcga gtcgaagccg aggtcgcgga aggcacggtc
     9121 cgacgcgacc gcgtccgcgc tgtcgtgagc gaggacatcg gcggcctggg cacgcaccag
     9181 atcgcgcagc gcggcttcgc gcttctcccg gggcagggct tccagccggt cgtggagttc
     9241 cgcccgcccg gggtcggcgc cacccggtgt ggactgcttc cccgtggccg tggtccgcgc
     9301 gccgcgcagc tcgcggaaga gggggctgtc gacggagtcc gcttcgaagc gtgtccagtc
     9361 gatgtcggcg acggcgagga atgtctcgtc gtggtccaac gcctggtgca gtgccgaaat
     9421 cgccagctcg ggggacatgg ccagcatccc cgagcggctc atctgctcac cgacctcacc
     9481 ggagacgagg ccaccgccgg cccaggcgcc ccagccgatg gaggtggccg gaaggccatc
     9541 cgcacgccgc tgcgacgcca gcgcgtcgag ataggcatta cccgccgcgt aactcccctg
     9601 acccggacca cccaacgtgc ccgccgccga agagaacaac acaaacgccg acagatccat
     9661 ccccgccgtc aactcatgca gattccacgc cgcatccacc ttcggacgca acaccccagc
     9721 cgcacgctcc accgtcaggg cgtccacgac gccgtcgtcc agcacaccgg ccgtgtgcac
     9781 cacggcggtg agcggcaact ccgaaggaat cgcgtccagc accgcggcca gtgcgtcacg
     9841 gtccgccgcg tcgcacgccg ccaccgtcac ccgggccccg agctcctcca actccgcctt
     9901 caacccggcg gcaccctcgg catccatccc gcgacggctc gtcagcacca gatgctcggc
     9961 acccgtacgc gccagccagc gggccacatg accacccagc gcacccgtac caccggtcac
    10021 caacaccgaa ccacccgaac gccacccacc gacaccggtg gcctcagacg cggaagcccg
    10081 caccagccgc ttgacgaaca cacccgaacc acgcaccgcg acctgatcct caccgaccgc
    10141 gcctgccagc actccggcca gccggaccag cgcccggctg tccatggcct cgggcaggtc
    10201 cacaacaccg ccccagcgct ggggatactc cgcccccacg atccggccca ggccccacac
    10261 catcgactgc accgggctca ccagccggtc ggaacgaccc accgacaccg caccccgggt
    10321 accacaccac agcggagcca ccacacccgc atcgcccagc ccctgaacca gacccaccat
    10381 cgcggccaga ccacccggca ccacaccgaa cgccggatgc cgggactcgt ccagcgccag
    10441 cagcgagaac acacccgcca cgtccgacgg ctccaccgcc acgccgtcaa gcgccacgcg
    10501 cagccgctcc gcaacggcct cgcggtcatc cgcggccccg acgaccacgg agaccacatg
    10561 cgcgccgcga ccggtcaagc cgtccagcac ggtggcagcc agggtctcgt caccacaggc
    10621 ttccggaacg gccacgagcc aggtgcccga gagcgtcgac tcggacgcgg acgccagggg
    10681 cttccagacc gccttgtaac gccagctgtc caccgtgttc tgctcgcgcc gctgacggcg
    10741 ccaggacgac agcgcgggaa gcagcgccgt cagcgacgac tgccgctcct cgtcctccac
    10801 ctccaacgtc cgcgccagcg cctccagatc ctcgcgctcc accgcctccc agaagcgcgc
    10861 atccaccgca tcggcgctca agccgtcacc ggcggccgcc acctctgcgg ccgagagggc
    10921 gtccagccag taccgctggc gctggaaggc gtaggtcggc agctcgacac ggcgggcacg
    10981 gtgtccggcg aacaccttcc gccagtcaac cgtggcccca ttgacatgga gctcggcggc
    11041 ggaggtcagg aaccgctcca gaccaccctc gtcacgccgc agcgtgccca cgaccaccgc
    11101 ctgtgcgtcc gcggcctcca cggtctgctg cacgggaagg gtgagcaccg ggtgcgggct
    11161 cacctcgatg aacacgccgt gtccagtgtc gagcagggtg cgggtggtgg cctccagctc
    11221 aacggtctgc cgcaggttcc ggtaccagta ctcggcatcc agaccggccg tatccaccag
    11281 ctcaccggac accgtcgaat agaacggcac ctccgaggag cggggttcca gatccgccag
    11341 gaccctcagc agctcctcgc ggatcccctc cacatgcgcg gagtgcgagg cgtagtccac
    11401 cggaacccgg cggacccgca cctcctcacc ctccagctcc gccaccatct catccagcgc
    11461 acccggatca cccgagacca cgacggaacc cggaccgttg accgcggcca ccgagatcgc
    11521 accgtcccaa gcggcgatgc gctccttggc ccggtccgcc gacagtccaa cggacaccat
    11581 gccaccgtgg cccgccagac cggcggcgat ggcctgcgac cgcagcgcca ccaccttcgc
    11641 ggcgtcctcc agcgacaacg cacccgccac acacgccgcc gcgatctcgc cctggctgtg
    11701 acccatcacc gcatccggct ccacacccac cgagcgccac agcttcgcca gcgacaccat
    11761 caccgcgaac aacaccggct gcaccacatc cacccgatcg aaaccgggag caccctcgcc
    11821 accacgcagc acctcggtca gcgaccagtc cacatacgcc gacagagccg tctcacactc
    11881 gccgatcgcc tccgcgaaca ccggcgagga ctccagcagc cccaccgcca tgcccatcca
    11941 ctgcgccccc tgaccgggga acacaaacac cgaacggccc cgcgcatcag ccacgccacg
    12001 cgtcacaccc gaggccacct cgtccccggc caacgcgccc agccgctcca ggagttgctc
    12061 acggtcggca cccgtcacca ccccgcggtg ctcgaacacc gagcgcgacg tcaccagcga
    12121 gaacgccaca gcggcggcgt ccagctccgg gcgctcgatc acgaactccc gcagccgctc
    12181 ggcctgcgcc cgcaggccct ccgggctacg gccggacacc agccacgcca ccggaccgcc
    12241 gacggcctcg gcctcggcat cctcggccgc ctcgacctcc ggggcctgct ccaggatcgc
    12301 gtgcgagttg gtcccgctca cgccgaagga cgacacgccg gcgcggcgcg ggtggtccga
    12361 ctccggccag gcggtggcct cggtgagcag cgcgatgtcg cccgccgacc agtccacgtg
    12421 ctgtgacggc tcatcgatgt gcagcgactt cggcaacacg ccgtgccgca tcgccatcac
    12481 catcttgatg acaccggcca caccggccgc cgcctgcgaa tggccgatgt tcgacttcac
    12541 cgatccgagc cacagcggct ggtccgtggg ccggtcctgg ccgtaggtgg ccagcagagc
    12601 ctgcgcctcg atcgggtcac ccagcgacgt acccgtaccg tgcgcctcca ccgcgtcgac
    12661 ctctgcgccc gacagccggg cggtcttgag cgccgcgcgg atcacccgct gctgggacgg
    12721 gccgttcggc gccgtcagac cgttggacgc gccgtcctgg ttgaccgccg aaccccggac
    12781 gagggccagc acctcgtggc cgttgcgccg ggcgtccgac agccgctcga cgagcagcag
    12841 cccgacgccc tcggcgaagc cgaatccatc ggcgtcattg ctgaacgcct tgcacttgcc
    12901 gtcggcggac agcgcgcgct gacggctgaa gtccaccagt ccggcctgtg tggacatcac
    12961 cgtcgcgcca ccggcgagcg ccaagtcgca ctcgccctgg cgcagcgcct ggaccgcgag
    13021 gtgcagcgcg accagcgacg acgagcacgc ggtgtccacc gtcaccgcgg gcccctccaa
    13081 gcccaaggtg taggagatac ggcccgaggc cacgctgccc gcactgccgg tgccgaggta
    13141 gccctcaaag ccttcggggg cgttgccttg cagccgggtg ccgtagtcgt tgtacacaac
    13201 gccgacgaag acgccggtcc ggcttccctt cgccgactcg gggtcgatac cggcccgctc
    13261 gaacgcctcc catgaggtct ccagcagcag ccgctgctgc gggtccatcg acagcgcctc
    13321 acggggcgag atcccgaaga acgccgggtc gaactggtcg gcgtcgtaga ggaagccacc
    13381 gttgcgggcg tagtacgtgc cctcgcgcgc ggggtccggg tcgtatgtcg tctcgaggtc
    13441 ccagccacgg ttggacggga gcgaggcggt ggcgtcggtg ccccccatca ccaggtgcca
    13501 cagttcctcg ggcgtccgca ccccaccggg gaatcggcag ctcatggaga cgatcgcgat
    13561 cggatcgtcg tccgtgcggg acagggcctc ggctgatccg cccgccgtcg gtgccgcggt
    13621 ggccgtgccc tgggacccga ggatctccga acgcagatgg cccgccagta ccgtcgggtt
    13681 cgggtagtcg aaaacgagcg tcgcgggcag gcgcaaaccg gtttccgcac tcagccggtt
    13741 gcgcagttcc acggccgtga gcgagtcgaa gcccagctcc ttgaagggcc gtcccacctc
    13801 gacggtgtcc gagttcgcgt ggcccagggc ggcggccacc tggatacgga tgagctcctc
    13861 cagcaggaac tgctcctggt ccgcctcgga catgctgacc agtcgccgcc gcaggcgggc
    13921 ggcgatgtcg tccacgtccg cgtctccggc accggcgacg cgccggaccg tcatccccgg
    13981 tacgacattg cggaagaggg cggggagttc ggcgccctgc gcacgcagcg ccgggatatc
    14041 cagccggaag agaaccggga cgaccgcatc cgagaccagg gcggcgtcga acagctcaag
    14101 gccctcgtcc gtggccagcg gcagcacgcc cgagcgggat attcgctgga tgtcgtcctc
    14161 gccgaggtgt ccggtcatgc cactggcctc ggcccacaga ccccacgcca tcgacacacc
    14221 cggcagcccc tgcgcccgcc gccacgaggc gagaccatcc aggaacacat tcgcagccgc
    14281 gtagttgctc tgcccggcac cacccagcac accagtggcc gacgagaaca gcacgaacgc
    14341 cgacagatcc atccccgccg tcagctcatg cagattccac gcagcgtcca ccttcgcccg
    14401 caacaccggc tcaacccgct cacgcgtcaa cgacgtcagc aacccgtcat ccagcacacc
    14461 cgccgcatgc accacaccac tgagcgcaaa accctccggc aaccccgaca acaccccggc
    14521 caaagcctca ccatccgcgg catcacacgc cgcgatcacc acctcagcac ccgcccctcc
    14581 aactccgccc gcaactccgc cgcaccctcg gcctccgcac cacgacgcga caacaacacc
    14641 agcctgctca ccccatgccg caccaccaga tgccgcgaca ccacaccacc caacacaccc
    14701 gtaccacccg tcaccaacac cgcacccgaa ccaaacccac ccgacacctc acccgacacc
    14761 cgcacccgac ccagacgcgg cacccgcacc acacccgaac gcaccaccac ctgctcctca
    14821 cccagagcca gcaccccggg cagaacgcca ccgacaccct ccacatcatc ggtgtccacc
    14881 agcaccagac gccccgggtt ctccgactgc gcggaccgca ctagccccca caccgccgcc
    14941 ccggccatgt cctccacacc atcgcccgca tcgacagcac cccgcgtcac caccaccaac
    15001 cgctcacccg cgagatcctc atccgccacc cacgcccgca cccgctccag gacctcaagg
    15061 acccggccat acacctcacc caccacatcc ggaccctcgg aaacgacccg caccacctca
    15121 gtccgcgacg ccacctcacc cccggccgcc acagccccag gcgcgtccac ccactccacc
    15181 cggaacaacc catcgcgcgc cgctccgccg accgcgttca gctgatccgc gtcgaccggg
    15241 cgcagcacca gcgactcgac cgaggccacc ccacgcccgg actcatcccc caccagcacc
    15301 gacaccgcat ccgacccagc acccaccgac gccaaccgca cccgcaacga cgtcgcaccc
    15361 accgcctcca aagcgaaccc acgccacgag aacggcaaca aactccccga accacccgca
    15421 agagccccac tcacacccaa cgcatgcaac gccgcatcga acaacgccgg atgcaaacca
    15481 aactgccccg cccgctcccg ctccccctcc ggaagcccaa cctcagcaaa cacctcacca
    15541 tcacgccgcc acgcacgcct caacccctga aaaacaggcc catactccaa cccgttctcc
    15601 g
//
