LOCUS       NZ_CP019462            15584 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete
            sequence.
ACCESSION   NZ_CP019462
VERSION     NZ_CP019462.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 15584)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 15584)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 15584
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019462.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     gene            complement(join(14254..15584,1..490))
                     /locus_tag="BV401_RS45435"
     CDS             complement(join(14254..15584,1..490))
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (2-30). E-value:
                     1.7e-11. Score: 35.4. Matches aSDomain:
                     nrpspksdomains_BV401_RS45435_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (34-460). E-value:
                     4.7e-182. Score: 597.5. Matches aSDomain:
                     nrpspksdomains_BV401_RS45435_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761156.1"
                     /locus_tag="BV401_RS45435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_087684499.1"
                     /sec_met_domain="mod_KS (E-value: 3.4e-228, bitscore:
                     745.9, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-93, bitscore:
                     301.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETKLRDYLKRATASLHETRQELKELKDRDREPIAIVGMGCRYP
                     GGVESPEDLWELVASGTDAVSTFPVDRGWDEDLYDPDPEKPGKSYTREGGFLHNANGFD
                     ASFFGMSPREALATDPQQRLLLETSWEALERAGIDPASARGSRTGVFVGVMSTTTAPAS
                     KSIPEGLEGHLGNGSAGSVASGRISYTFGFEGPAVTVDTACSSSLVALQLAVQALHKGD
                     CSLALAGGVAMMATPGVFIEFSRLRGLAVDGRCKSFSNAADGTGWSEGAGVLLLERLSD
                     AQRNGHQVLAVVRGAAVNQDGASSRLTAPNGPSQQRVIRDALRNAGLSAADVDAVEAHG
                     TGTPLGDPIEAQALLATYGKERAGADRPLWLGSFKSNVGHTQAAAGVGGVIKMVMAMRH
                     GVLPKTLHVEEPSEHVDWSAGAVSLLTESTPWPETGEPRRAGVSSFGVSGTNAHVILEQ
                     APEAEAAGDAEPEVADGPVAWVVSGHGAEGLRAQAERLRAYVAGRSELGAADVARSLVM
                     TRSVLDHRAVLVGRDRDELLSGLGAVAEKSALPGVVVGESAPPGRSVFVFPGQGAQWVG
                     MAVGLLESSPVFAEAVGECEAALSAYVTGR"
     aSDomain        complement(join(14695..15584,1..388))
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45435_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="4.70E-182"
                     /label="BV401_RS45435_PKS_KS.1"
                     /locus_tag="BV401_RS45435"
                     /protein_end="460"
                     /protein_start="34"
                     /score="597.5"
                     /tool="antismash"
                     /translation="IAIVGMGCRYPGGVESPEDLWELVASGTDAVSTFPVDRGWDEDLY
                     DPDPEKPGKSYTREGGFLHNANGFDASFFGMSPREALATDPQQRLLLETSWEALERAGI
                     DPASARGSRTGVFVGVMSTTTAPASKSIPEGLEGHLGNGSAGSVASGRISYTFGFEGPA
                     VTVDTACSSSLVALQLAVQALHKGDCSLALAGGVAMMATPGVFIEFSRLRGLAVDGRCK
                     SFSNAADGTGWSEGAGVLLLERLSDAQRNGHQVLAVVRGAAVNQDGASSRLTAPNGPSQ
                     QRVIRDALRNAGLSAADVDAVEAHGTGTPLGDPIEAQALLATYGKERAGADRPLWLGSF
                     KSNVGHTQAAAGVGGVIKMVMAMRHGVLPKTLHVEEPSEHVDWSAGAVSLLTESTPWPE
                     TGEPRRAGVSSFGVSGTNAHVILEQAP"
     source          1..15584
                     /collection_date="1998-01-01"
                     /country="China:Yunnan"
                     /culture_collection="CGMCC:0516"
                     /db_xref="taxon:75293"
                     /isolation_source="soil sample"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces autolyticus"
                     /plasmid="unnamed5"
                     /strain="CGMCC0516"
     region          1..15584
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..15584
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..15584
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[571:10778](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(572..10778)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS_motif       complement(110..136)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45435_0001"
                     /evalue="7.60E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="BV401_RS45435"
                     /protein_end="127"
                     /protein_start="118"
                     /score="9.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     misc_feature    163..179
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.48"
                     /tool="antismash"
     aSDomain        complement(401..484)
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45435_PKS_Docking_Nterm.
                     1"
                     /evalue="1.70E-11"
                     /label="BV401_RS45435_PKS_Docking_Nterm.1"
                     /locus_tag="BV401_RS45435"
                     /protein_end="30"
                     /protein_start="2"
                     /score="35.4"
                     /tool="antismash"
                     /translation="ETKLRDYLKRATASLHETRQELKELKDR"
     gene            complement(572..10778)
                     /locus_tag="BV401_RS45440"
                     /pseudo=""
     CDS             complement(572..10778)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (0-422). E-value:
                     4.6e-180. Score: 591.0. Matches aSDomain:
                     nrpspksdomains_BV401_RS45440_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (527-825). E-value: 6.6e-112.
                     Score: 365.6. Matches aSDomain:
                     nrpspksdomains_BV401_RS45440_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1171-1349). E-value: 2.7e-63.
                     Score: 205.2. Matches aSDomain:
                     nrpspksdomains_BV401_RS45440_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608235.1"
                     /locus_tag="BV401_RS45440"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="mod_KS (E-value: 4.9e-227, bitscore:
                     742.1, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-90, bitscore:
                     291.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.5e-113, bitscore:
                     365.6, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.7e-66, bitscore:
                     209.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCRFPGGVRTPEELWHLVMGGTDATASLPSNRGWDLETTYDPDP
                     AREGTYYARNGGFLYDADQFDPAFFGISPREALSMDPQQRLLLETSWEAFERAGIDPES
                     AKGSRTGVFVGVVYNDYGTRLQGNAPEGFEGYLGTGSAGSVASGRISYTLGLEGPAVTV
                     DTACSSSLVALHLAVQALRQGECDLALAGGATVMSTQAGLVDFSRQRALSADGKCKAFS
                     NDADGFGFAEGVGLLLVERLSDARRNGHEVLALVRGSAVNQDGASNGLTAPNGPSQQRV
                     IRAALKTARLSGAEVDAVEAHGTGTSLGDPIEAQALLATYGQDRPTDQPLWLGSVKSNI
                     GHSQAAAGVAGVIKMVMAMRHGVLPKSLHIDEPSQHVDWSAGDIALLTEATAWPESDHP
                     RRAGVSSFGVSGTNSHAILEQAPEVEAAEDAEAEAVGGPVAWLVSGRSPEGLRAQAERL
                     REFVIERPELDAAAVAFSLVTSRSVFEHRGVVTGADREQLLERLGALAGDEVASGVTRG
                     VADARGRSVFVFPGQGAQWMGMAVGLLESSPVFAEAIGECETALSAYVDWSLTEVLRGG
                     EGAPGFDRVDVVQPVLFAVMVSLAKLWRSVGVEPDAVMGHSQGEIAAACVAGALSLEDA
                     AKVVALRSQAIAAGLAGHGGMVSVGLSADRAKERIAAWDGAISVAAVNGPGSVVVSGDP
                     GALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIREELLRVLADLEPRSSEVPFYSTVS
                     GELVDTAGLDAEYWYRNLRQTVELEATTRTLLDTGHGVFIEVSPHPVLTLPVQQTVEAA
                     DAQAVVVGTLRRDEGGLERFLTSAAELHVNGATVDWRKVFAGHRARRVELPTYAFQRQR
                     YWLDALSAAEVAAAGDGLSADAVDARFWEAVEREDLEALARTLEVEDEERQSSLTALLP
                     ALSSWRRQRREQNTVDSWRYKAVWKPLASASESTLSGTWLVAVPEACGDETLAATVLDG
                     LTGRGAHVVSVVVGAADDREAVAERLRVALDGVAVEPSDVAGVFSLLALDESRHPAFGV
                     VPGGLAAMVGLVQGLGDAGVVAPLWCGTRGAVSVGRSDRLVSPVQSMVWGLGRIVGAEY
                     PQRWGGVVDLPEAMDSRALVRLAGVLAGAVGEDQVAVRGSGVFVKRLVRASASEATGVG
                     GWRSGGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMDAEGAAGLKAELEELGAR
                     VTVAACDAADRDALAAVLDAIPSELPLTAVVHTAGVLDDGVVDALTVERAAGVLRPKVD
                     AAWNLHELTAGMDLSAFVLFSSAAGTLGGPGQGSYAAGNAYLDALASQRRADGLPATSI
                     GWGAWAGGGLVSGEVGEQMSRSGCWPCPPSWRFRHCTRRWTTTRHSSPSPTSTGHASKR
                     TPSTAPSSASCAARGPRPRGSSPHRVAPTPGGRNSTTGWKPCPGRSAKPRCAIWCVPRP
                     PMSSLTTARTRSRRTVPSATSASTR"
     misc_feature    1521..1536
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    2376..2390
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    2953..2967
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    complement(3547..3562)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     misc_feature    4303..4318
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     aSDomain        complement(6732..7265)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45440_PKS_KR.1"
                     /evalue="2.70E-63"
                     /label="BV401_RS45440_PKS_KR.1"
                     /locus_tag="BV401_RS45440"
                     /protein_end="1349"
                     /protein_start="1171"
                     /score="205.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMDAEGAAGLK
                     AELEELGARVTVAACDAADRDALAAVLDAIPSELPLTAVVHTAGVLDDGVVDALTVERA
                     AGVLRPKVDAAWNLHELTAGMDLSAFVLFSSAAGTLGGPGQGSYAAGNAYLDALASQRR
                     ADGLPATSIGWGAWA"
     aSModule        complement(6732..10778)
                     /domains="nrpspksdomains_BV401_RS45440_PKS_KS.1"
                     /domains="nrpspksdomains_BV401_RS45440_PKS_AT.1"
                     /domains="nrpspksdomains_BV401_RS45440_PKS_KR.1"
                     /incomplete
                     /locus_tags="BV401_RS45440"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(6777..6881)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0013"
                     /evalue="1.60E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="BV401_RS45440"
                     /protein_end="1334"
                     /protein_start="1299"
                     /score="59.3"
                     /tool="antismash"
                     /translation="AFVLFSSAAGTLGGPGQGSYAAGNAYLDALASQRR"
     CDS_motif       complement(6909..6938)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0012"
                     /evalue="3.20E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="BV401_RS45440"
                     /protein_end="1290"
                     /protein_start="1280"
                     /score="10.9"
                     /tool="antismash"
                     /translation="PKVDAAWNLH"
     CDS_motif       complement(7164..7262)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0011"
                     /evalue="3.00E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="BV401_RS45440"
                     /protein_end="1205"
                     /protein_start="1172"
                     /score="45.5"
                     /tool="antismash"
                     /translation="SVLVTGGTGALGGHVARWLARTGAEHLVLTSRR"
     aSDomain        complement(8304..9197)
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45440_PKS_AT.1"
                     /evalue="6.60E-112"
                     /label="BV401_RS45440_PKS_AT.1"
                     /locus_tag="BV401_RS45440"
                     /protein_end="825"
                     /protein_start="527"
                     /score="365.6"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: emal"
                     /tool="antismash"
                     /translation="VFPGQGAQWMGMAVGLLESSPVFAEAIGECETALSAYVDWSLTEV
                     LRGGEGAPGFDRVDVVQPVLFAVMVSLAKLWRSVGVEPDAVMGHSQGEIAAACVAGALS
                     LEDAAKVVALRSQAIAAGLAGHGGMVSVGLSADRAKERIAAWDGAISVAAVNGPGSVVV
                     SGDPGALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIREELLRVLADLEPRSSEVPFY
                     STVSGELVDTAGLDAEYWYRNLRQTVELEATTRTLLDTGHGVFIEVSPHPVLTLPVQQT
                     VEAADAQAVVVGTLRRD"
     CDS_motif       complement(8376..8405)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0010"
                     /evalue="3.00E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="BV401_RS45440"
                     /protein_end="801"
                     /protein_start="791"
                     /score="10.2"
                     /tool="antismash"
                     /translation="FIEVSPHPVL"
     CDS_motif       complement(8451..8495)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0009"
                     /evalue="6.90E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="BV401_RS45440"
                     /protein_end="776"
                     /protein_start="761"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRQTVE"
     CDS_motif       complement(8601..8633)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0008"
                     /evalue="5.70E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="BV401_RS45440"
                     /protein_end="726"
                     /protein_start="715"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VDYASHSAHVE"
     CDS_motif       complement(8700..8741)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0007"
                     /evalue="7.30E-03"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="BV401_RS45440"
                     /protein_end="693"
                     /protein_start="679"
                     /score="8.9"
                     /tool="antismash"
                     /translation="AAVNGPGSVVVSGD"
     CDS_motif       complement(8850..8960)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0006"
                     /evalue="1.70E-20"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="BV401_RS45440"
                     /protein_end="643"
                     /protein_start="606"
                     /score="64.7"
                     /tool="antismash"
                     /translation="GVEPDAVMGHSQGEIAAACVAGALSLEDAAKVVALRS"
     CDS_motif       complement(8964..9032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0005"
                     /evalue="6.60E-12"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="BV401_RS45440"
                     /protein_end="605"
                     /protein_start="582"
                     /score="37.2"
                     /tool="antismash"
                     /translation="DRVDVVQPVLFAVMVSLAKLWRS"
     CDS_motif       complement(9147..9203)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0004"
                     /evalue="1.20E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BV401_RS45440"
                     /protein_end="544"
                     /protein_start="525"
                     /score="26.7"
                     /tool="antismash"
                     /translation="VFVFPGQGAQWMGMAVGLL"
     aSDomain        complement(9513..10778)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45440_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="4.60E-180"
                     /label="BV401_RS45440_PKS_KS.1"
                     /locus_tag="BV401_RS45440"
                     /protein_end="422"
                     /protein_start="0"
                     /score="591.0"
                     /tool="antismash"
                     /translation="MSCRFPGGVRTPEELWHLVMGGTDATASLPSNRGWDLETTYDPDP
                     AREGTYYARNGGFLYDADQFDPAFFGISPREALSMDPQQRLLLETSWEAFERAGIDPES
                     AKGSRTGVFVGVVYNDYGTRLQGNAPEGFEGYLGTGSAGSVASGRISYTLGLEGPAVTV
                     DTACSSSLVALHLAVQALRQGECDLALAGGATVMSTQAGLVDFSRQRALSADGKCKAFS
                     NDADGFGFAEGVGLLLVERLSDARRNGHEVLALVRGSAVNQDGASNGLTAPNGPSQQRV
                     IRAALKTARLSGAEVDAVEAHGTGTSLGDPIEAQALLATYGQDRPTDQPLWLGSVKSNI
                     GHSQAAAGVAGVIKMVMAMRHGVLPKSLHIDEPSQHVDWSAGDIALLTEATAWPESDHP
                     RRAGVSSFGVSGTNSHAILEQAP"
     CDS_motif       complement(9735..9779)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0003"
                     /evalue="1.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="BV401_RS45440"
                     /protein_end="348"
                     /protein_start="333"
                     /score="11.6"
                     /tool="antismash"
                     /translation="GSVKSNIGHSQAAAG"
     CDS_motif       complement(9840..9884)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0002"
                     /evalue="3.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BV401_RS45440"
                     /protein_end="313"
                     /protein_start="298"
                     /score="12.8"
                     /tool="antismash"
                     /translation="VEAHGTGTSLGDPIE"
     CDS_motif       complement(10260..10307)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45440_0001"
                     /evalue="7.10E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="BV401_RS45440"
                     /protein_end="173"
                     /protein_start="157"
                     /score="21.0"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     aSDomain        complement(<10947..11090)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45950_ACP.1"
                     /evalue="7.40E-20"
                     /label="BV401_RS45950_ACP.1"
                     /locus_tag="BV401_RS45950"
                     /protein_end="166"
                     /protein_start="118"
                     /score="63.0"
                     /tool="antismash"
                     /translation="ELIRIQVAAALGHANSDTVEVGRPFKELGFDSLTAVELRNRLSAE
                     TGL"
     gene            complement(<10947..11444)
                     /locus_tag="BV401_RS45950"
                     /pseudo=""
     CDS             complement(<10947..11444)
                     /NRPS_PKS="Domain: ACP (118-166). E-value: 7.4e-20. Score:
                     63.0. Matches aSDomain: nrpspksdomains_BV401_RS45950_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="BV401_RS45950"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="beta-ketoacyl reductase"
                     /pseudo=""
                     /sec_met_domain="PP-binding (E-value: 4.3e-10, bitscore:
                     28.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWGLWAEASGMTGHLGEDDIQRISRSGVLPLATDEGLELFDAAL
                     VSDAVVPVLFRLDIPALRAQGAELPALFRNVVPGMTVRRVAGAGDADVDDIAARLRRRL
                     VSMSEADQEQFLLEELIRIQVAAALGHANSDTVEVGRPFKELGFDSLTAVELRNRLSAE
                     TGL"
     gene            complement(11408..13330)
                     /locus_tag="BV401_RS45450"
     CDS             complement(11408..13330)
                     /EC_number="6.4.-.-"
                     /GO_component="GO:0034081 - polyketide synthase complex
                     [Evidence IEA]"
                     /GO_process="GO:0030639 - polyketide biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_DH (13-179). E-value: 3.4e-62.
                     Score: 201.6. Matches aSDomain:
                     nrpspksdomains_BV401_RS45450_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (457-626). E-value: 8.3e-53.
                     Score: 171.0. Matches aSDomain:
                     nrpspksdomains_BV401_RS45450_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020243.4"
                     /locus_tag="BV401_RS45450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_250644896.1"
                     /sec_met_domain="adh_short (E-value: 7.8e-60, bitscore:
                     190.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDVGSVGLGSLGHPLLGAVVSLASGGGVLLSGRLSLATHEWLAD
                     HAVHGVMLLPGTAFVELVVRAGDQVGCGRVEELVIEAPLIVPEKGGVHLQVEVGEADAS
                     GFREVSVYSREEADGDGAAWVRHAHGVLGSAVPSSETQYDFGVWPPVGAELVDVSGEYV
                     RAAENGLEYGPVFQGLRRAWRRDGEVFAEVGLPEGERERAGQFGLHPALFDAALHALGV
                     SGALAGGSGSLLPFSWRGFALEAVGATSLRVRLASVGAGSDAVSVLVGDESGRGVASVE
                     SLVLRPVDADQLNAVGGAARDGLFRVEWVDAPGAVAAGGEVASRTEVVRVVSEGPDVVG
                     EVYGRVLEVLERVRAWVADEDLAGERLVVVTRGAVDAGDGVEDMAGAAVWGLVRSAQSE
                     NPGRLVLVDTDDVEGVGGVLPGVLALGEEQVVVRSGVVRVPRLGRVRVSGEVSGGFGSG
                     AVLVTGGTGVLGGVVSRHLVVRHGVSRLVLLSRRGAEAEGAAELRAELEGAGAEVVIAA
                     CDAADGEALAGVLSGLPEGFALSGVVHAAGVLDDGLLTSLTRERVEPVLRAKVDAAWNL
                     HELTAGMDLSAFVLFSSATGVLGGAGQSNYAAANVFLDGLASWRRAQGCRVCRWRGVCG
                     PRPVA"
     aSDomain        complement(11453..11959)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45450_PKS_KR.1"
                     /evalue="8.30E-53"
                     /label="BV401_RS45450_PKS_KR.1"
                     /locus_tag="BV401_RS45450"
                     /protein_end="626"
                     /protein_start="457"
                     /score="171.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GAVLVTGGTGVLGGVVSRHLVVRHGVSRLVLLSRRGAEAEGAAEL
                     RAELEGAGAEVVIAACDAADGEALAGVLSGLPEGFALSGVVHAAGVLDDGLLTSLTRER
                     VEPVLRAKVDAAWNLHELTAGMDLSAFVLFSSATGVLGGAGQSNYAAANVFLDGLASWR
                     RAQGCR"
     aSModule        complement(11453..13291)
                     /domains="nrpspksdomains_BV401_RS45450_PKS_DH.1"
                     /domains="nrpspksdomains_BV401_RS45450_PKS_KR.1"
                     /incomplete
                     /locus_tags="BV401_RS45450"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(11468..11572)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45450_0004"
                     /evalue="3.00E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="BV401_RS45450"
                     /protein_end="621"
                     /protein_start="586"
                     /score="61.6"
                     /tool="antismash"
                     /translation="AFVLFSSATGVLGGAGQSNYAAANVFLDGLASWRR"
     misc_feature    complement(11548..11562)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.09"
                     /tool="antismash"
     CDS_motif       complement(11600..11629)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45450_0003"
                     /evalue="6.40E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="BV401_RS45450"
                     /protein_end="577"
                     /protein_start="567"
                     /score="10.1"
                     /tool="antismash"
                     /translation="AKVDAAWNLH"
     misc_feature    11774..11788
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     CDS_motif       complement(11855..11953)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45450_0002"
                     /evalue="9.10E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BV401_RS45450"
                     /protein_end="492"
                     /protein_start="459"
                     /score="21.5"
                     /tool="antismash"
                     /translation="VLVTGGTGVLGGVVSRHLVVRHGVSRLVLLSRR"
     misc_feature    complement(12455..12468)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     aSDomain        complement(12794..13291)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45450_PKS_DH.1"
                     /evalue="3.40E-62"
                     /label="BV401_RS45450_PKS_DH.1"
                     /locus_tag="BV401_RS45450"
                     /protein_end="179"
                     /protein_start="13"
                     /score="201.6"
                     /tool="antismash"
                     /translation="HPLLGAVVSLASGGGVLLSGRLSLATHEWLADHAVHGVMLLPGTA
                     FVELVVRAGDQVGCGRVEELVIEAPLIVPEKGGVHLQVEVGEADASGFREVSVYSREEA
                     DGDGAAWVRHAHGVLGSAVPSSETQYDFGVWPPVGAELVDVSGEYVRAAENGLEYGPVF
                     QGL"
     CDS_motif       complement(13133..13207)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45450_0001"
                     /evalue="5.70E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="BV401_RS45450"
                     /protein_end="66"
                     /protein_start="41"
                     /score="31.6"
                     /tool="antismash"
                     /translation="WLADHAVHGVMLLPGTAFVELVVRA"
     gene            complement(13237..14091)
                     /locus_tag="BV401_RS45455"
     CDS             complement(13237..14091)
                     /EC_number="2.3.1.-"
                     /NRPS_PKS="Domain: PKS_AT (1-200). E-value: 1e-52. Score:
                     171.3. Matches aSDomain:
                     nrpspksdomains_BV401_RS45455_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="BV401_RS45455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase domain-containing protein"
                     /protein_id="WP_087684498.1"
                     /sec_met_domain="PKS_AT (E-value: 8.7e-54, bitscore: 171.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWAGGLSLEDAAKVVALRSQAIAVGLAGRGGMVSVGCPRSSGGAY
                     RPVGWGDFGGGGQWSGSVVVAGDPDALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIR
                     EELLRVLADLQPRSSEVPFYSTVTGELVDTAQLDAEYWYRNLRQTVELESTTRTLLDAG
                     HTVFIEVSPHPVLTLPVQQTVEAAESRAVVVGTLRRDEGGAERFLTSAAELHVSGARVD
                     WQKVFAGHGAHRVELPTYAFQHERFWLDAPAVWVMWVRWGWVRWGIRCWVRWCRWRVVA
                     GCC"
     CDS_motif       complement(13393..13410)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45455_0004"
                     /evalue="1.30E+01"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="BV401_RS45455"
                     /protein_end="233"
                     /protein_start="227"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="AGHGAH"
     aSDomain        complement(13492..14088)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: False, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS45455_PKS_AT.1"
                     /evalue="1.00E-52"
                     /label="BV401_RS45455_PKS_AT.1"
                     /locus_tag="BV401_RS45455"
                     /protein_end="200"
                     /protein_start="1"
                     /score="171.3"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="WAGGLSLEDAAKVVALRSQAIAVGLAGRGGMVSVGCPRSSGGAYR
                     PVGWGDFGGGGQWSGSVVVAGDPDALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIRE
                     ELLRVLADLQPRSSEVPFYSTVTGELVDTAQLDAEYWYRNLRQTVELESTTRTLLDAGH
                     TVFIEVSPHPVLTLPVQQTVEAAESRAVVVGTLRRD"
     CDS_motif       complement(13564..13593)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45455_0003"
                     /evalue="3.80E-04"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="BV401_RS45455"
                     /protein_end="176"
                     /protein_start="166"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FIEVSPHPVL"
     CDS_motif       complement(13639..13683)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45455_0002"
                     /evalue="8.80E-06"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="BV401_RS45455"
                     /protein_end="151"
                     /protein_start="136"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRQTVE"
     CDS_motif       complement(13789..13821)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45455_0001"
                     /evalue="7.70E-05"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="BV401_RS45455"
                     /protein_end="101"
                     /protein_start="90"
                     /score="15.2"
                     /tool="antismash"
                     /translation="VDYASHSAHVE"
     CDS_motif       complement(14329..14385)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45435_0005"
                     /evalue="2.10E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BV401_RS45435"
                     /protein_end="582"
                     /protein_start="563"
                     /score="29.0"
                     /tool="antismash"
                     /translation="VFVFPGQGAQWVGMAVGLL"
     CDS_motif       complement(14917..14961)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45435_0004"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="BV401_RS45435"
                     /protein_end="386"
                     /protein_start="371"
                     /score="11.5"
                     /tool="antismash"
                     /translation="GSFKSNVGHTQAAAG"
     CDS_motif       complement(15025..15069)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45435_0003"
                     /evalue="1.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BV401_RS45435"
                     /protein_end="350"
                     /protein_start="335"
                     /score="13.9"
                     /tool="antismash"
                     /translation="VEAHGTGTPLGDPIE"
     CDS_motif       complement(15445..15492)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS45435_0002"
                     /evalue="2.50E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="BV401_RS45435"
                     /protein_end="210"
                     /protein_start="194"
                     /score="22.4"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
ORIGIN
        1 tggatgcggg agccgtagtc gttgacatca cgccgacgaa cacgccggtg cggctgccac
       61 gcgcggacgc cgggtcgatg cccgcgcgct ccagcgcctc ccatgaggtc tccagcagca
      121 gccgctgctg tgggtcggtc gccagcgcct cacgcggact catgccgaag aaggaggcgt
      181 cgaagccgtt cgcgttgtgc aggaacccgc cctcacgcgt atagctcttg cccggcttct
      241 ccgggtcggg gtcgtacagg tcctcgtccc acccacggtc cacggggaag gtggacaccg
      301 cgtcggtgcc cgaggcgacc agctcccaca ggtcttcggg cgactccact ccgccgggat
      361 acctgcaccc catgccgacg atcgcgatgg gttcccggtc cctgtccttg agttccttca
      421 gctcttgacg agtttcgtgc aggctggccg tcgcgcgctt gaggtagtcg cgcagcttgg
      481 tctcactcac cgcttcttgt cactcctctg agcaccccgg acagggtgga aagccttcgg
      541 ccggtaactt ccggggacgg gggcgtccgc gtcacgagag ctcctcgtcg aggaagtcga
      601 agatctcgtc gtcggtggcc gactcgaact tgtcggcggc gacgacccca ccgttcgcgg
      661 tctccgtctg ctgccccgcg gtcagcttcg ccagcacctg ctgcaagcgc gaggtgagac
      721 gtgccgtggc ggcttcgtcc gccaccacct cggcgaagga gcgctccagc ttctccagct
      781 ccgacagaac cggcagcacc agcgatgcgt ccggctcttc cgcgacgagc tcctgcgcca
      841 ggtagccggc cagcgccctg gacgtcgtgt agtcgaacag cagggtggcg gggagccgca
      901 gaccggtcac cgtgcccagc tggttgcgca gtccgaccgc ggtcagcgag tcgaagccca
      961 gctcgaggaa gccacggtcg gggcgatcat gcgggggctg tcgtggccca gcgccatggc
     1021 cgcgtgctcc gtgaccagtt cgaggagcgc ctgctgccgg gcggcggggt tcatcgagcc
     1081 gatccggcgg cgcagttcgg cggggtcggc gccggatccg cccgtggacg ccttcgcggg
     1141 gccgcgccgg ccgtggtccg gatgatgccc cgcagcagcg ccgggatcgg cccgtcctgg
     1201 gctcgccacg ccgaggcgtt gagccgtgcc gggaccagag tgccgcgtcg atgccgcggg
     1261 cggcgtcgaa cagggccagt gcctcctcgg aggacatcgg gtcacgcctt cgcgggcgag
     1321 gcgccgcata tgggcctcgt ccagcttgcc cgtcataccg ctgcgctcct cccacaggcc
     1381 ccaggccagc gactgggcgg gaaggccctc ggcccggcgc cggtgggcga acgcgtccag
     1441 gaaggcgttg gcggccgcgt agttggcctg gccggtgccg ccgagggttc cggagagcga
     1501 ggagaagagc acgaacgcgg acaggtcgag accggcggtc agctcgtgca gattgagcac
     1561 cgcgtccacc ttgggccgca gcacacggtc cacccgctcg ggcgtgaggg cttcgacgac
     1621 gccgtcgtcc agcactccgg cggtgtgcac cacggcggtg agcgggtgtt cgtccggcag
     1681 ggaggccaga agcgcggcga gggagtcgcg gtcggcggtg tcacaggcgg cgaccacggc
     1741 gtgggcgccg aggtccgtca gctccgtccg cagttcggcc gcgccgtccg cggcgaggcc
     1801 gcggcggctg accagcacga ggtggcggac gccgtgctcg ccgacgaggt gcttggcgac
     1861 caggccgccg aggccggatg ccgccccggt gaccaggacg gtgccctgcg ggtcccaggt
     1921 gacgccggtc gtgaccgacc gtgcgtcgcc ctgctcggac gcgctgccat gcgccgccac
     1981 ccgggccagc cggccgacca ggaccgtgcc gttccggacc acgatctgtg gttcgtcggt
     2041 ggtgagcgcc gccgggagga tccggcgcga gccttccctg tcgtccaggt cggccaggac
     2101 gaaccggccg gggttctcgg actgggccga gcgcaccagg ccccagacgg ccgcactggc
     2161 ggggtcggcc acatcggtgt catcgcccgc ggcgatggcc ccccgggtga ggaagaccag
     2221 ccgggagccg ccgaggcggt tgtcggccag ccagctcttg agcaggtcga gggcgtggtg
     2281 gccggcttcc cgtaccgcct ccgccagttc ccgcgtccgg ccggtgcggg acacgttcgc
     2341 ggcgagtacg acgtcgggcg cggtcgcgcc cgcgtcgatg gcctcggcca gggccgcgag
     2401 gtccgggtag gtgtccacgg tgacatcggc cgatccgagg gcgccggtca gctcggcccg
     2461 gtcgggtccg acgagcgccc agcgcccggc ggccgcgccg ctcgtctccg gggcggtcgg
     2521 cacccagtcg acctggtaca gcgactcgtg cggctgggcg gagttgacct gctccggggc
     2581 cacgggccgc agtacgagcg agtcgaccga ggcgacgagc gcgccggaga cgtcggtgac
     2641 gtgcagggag accgtgtcct cgccgacgct ggtcagccgc acccgcagcg cggacgcgcc
     2701 gcttgcgtgg agggtcaccc cgttccacga gaacgggagg gtgctgccgt cgctgccgga
     2761 cggcttgaac gccacggtgt gcagcgaggc gtcgagcagc gccgggtgga gaccgtagcg
     2821 cgcggcctcg ccctcctgtg cctcgggcag gtcgacctcg gcgaagacct cgtcgccacg
     2881 gcgccaggcg gcgcgcagcc cctggaaggc cgggccgtag gcgaagccga cgtcgatgaa
     2941 ccggtcgtag agatcggcca cgtcgatggc ctccgcatcc gcgggcggcc acacggcgaa
     3001 gtcggcggcc acggactccg gtgccgtggt ggacaggtcc ctgctgagca ggccggtcgt
     3061 atggcgcgtc caggggtcgt ccggctgggc gtcctcgggc ctggagtaca gattgagcga
     3121 acgggcgccg gactcgtccg gctcgcccac ggcgagctgg atctggaccg cgccgcgtac
     3181 gggcaggacc aacggcattt cgatggtcag ttcctccacc cgctcgtagc ccacctgctc
     3241 ggcggcgcgc agggccagtt ccacgaaggc cgtgccgggg aagagcacgg tgtccgcgaa
     3301 ggcgtggtcg gccagccacg gctgggtggc gaccgacagg cgcccggtga acaggtaggt
     3361 gtcggtgtcg gccagggcga cggcggcgcc caggagcgga tggtcgggcg agtccaggcc
     3421 cgccgatgtc acatctccac tggcggccgg cgcggcttcg agccagtagc gctgccgctg
     3481 gaaggcgtag gtgggcagct ccacccgctg ggcgccacgc ccggcgaaca ccgcgtccca
     3541 cttcaccgtg acgccgtgca catggagttc ggccagcgcc atggtcagcg actgaagctc
     3601 gggccggtcc ttgcgcagtg cgggcacgag ggcgggagcc accgcgccac cgggttctgc
     3661 ggccgtcagg cagtcctgcg ccatcgcggt gagcacaccg tccgggccca cctcgacgaa
     3721 cgaggtcacg cccaggttct ccagggtcct taccccgtcc gcgaaccgca cggcctcgcg
     3781 cacatgccgg acccagtact ccggcgagca cacctcgtcc gcgtcggccg gggcgccggt
     3841 gacgttggac accagggaga tggtcggcgg ggcgaacaac agcccctcga caaccttccg
     3901 gaagtcaccg agcacaccgt ccatgcgcgg gagtggaagg cgtggctgac gcgcaggcgg
     3961 cgtgtcttac ggccctcccg ctcccactgt ccggcgatct ccagcacggc gggctcgtcg
     4021 cccgcgatga ccacggcggt ggggccgttg atggccgcga tgctcacctc ggcctctcga
     4081 ccggccagcg acgcggcgat ctcctcctcg ggcgcctgga cggccaccat cgcgccgcct
     4141 tcgggcagcg cctgcatcag ccggccacgg gccgccacca gggcgcacgc gtcctccagg
     4201 gagaacaccc cggccacatg ggcggcggcg acctcaccga tggagtggcc gatcagcaca
     4261 tccggggtga caccccagtg ctccagcagc cggaacagcg ccacctcgat ggcgaacagc
     4321 gcgggctggg tgaacgccgt ctggttcagc aactcggcgt cggcactgcc ctcgaccgcg
     4381 aacatcacct cggtcagcgg ccggtcgagc agcacatcga ggtaggcgca cacctcgtcc
     4441 agcgcctggg cgaacaccgg gaaggcgtcg tacagctccc ggcccatgcc cagccgctgc
     4501 gcgccctggc ccgagaacag gaacgccgtc ttgtgctcgg cccgtgccac gccctggatc
     4561 agcgtggccg cgttcccgcc cgccgccaac gcttcgagcc cggagcggaa ctgcgccggg
     4621 tcctccgcga ccacagcggc gcggtagggc agggcggaac gggtggtcgc cagcgagtag
     4681 ccgatgtcgg cgacatcacc ggcccgcgcg gtgcgcacac cgtcgaactc gcgcagccgc
     4741 ccggcctgag cgctcagcgc atcggcgttg ctgcccgaga gcagccaggg aaccaccgtg
     4801 agacccgcgg gcgaaccggt ggcctcgcca cccgtctccg gcgacggcga ctcaacgggg
     4861 tcggccgcct cgatgatcgt gtgcgcgttg gtgccgctga tcccgaagga cgacacggcc
     4921 gcccggcgcg ggcggtccgt ctccggccac gcggtcgcct cgttcagcag cgacacggcg
     4981 ccactggtcc agtcgatatg cggcgagggc tcgtccgcgt ggagcgtctt cggcagcacg
     5041 ccctcgcgca tggccatcac catcttgatg acacccgcga caccggccgc ggcctgcgtg
     5101 tgcccgatgt tcgacttgat cgagcccagc cacagcggct ggtcctcgga acgcgcctgg
     5161 ccgtacgtgg ccagcagcgc ctgcgcctcg atcgggtcac ccagcgaggt gcccgtgcca
     5221 tgtgcctcca ccgcgtccac atcggcggcc gacagacccg cgttttcaag ggccttgccg
     5281 atcacacgct gctgcgacgg gccgttcggc gccgtcagac cgttggacgc gccgtcctgg
     5341 ttgatcgccg aaccccggac gacggccagc accttgtggc cgcggcgccg ggcgtccgac
     5401 agccgctcca ccagcagcag acccacaccc tcggaccagc cggtgccatc ggcctcggcg
     5461 gagaacgcct tgcaccgtcc gtccggcgac agcacacgct ggcgctgaac tcgacgaacg
     5521 tgcccggcgt ggccatgatc gtcacaccgc cggccagcgc catgtcgcac tcgccctggc
     5581 gcagcgactg gcaggccagg tgcagggcga ccagcgacga cgaacacgcg gtgtccaccg
     5641 tcacggccgg ccctcgaagc cgaaggtgta ggagaggcgg ccggaggcga cgctggacgc
     5701 gctgccgagt ccgaggtagc cctgcacacc gtccggcgcg ctgatcgccc ggccgctgta
     5761 gtcctggtag ttcgagccga tgaagacacc cgcctggctg ccgcgcaacg ccgccgggtc
     5821 gattccggcc cgctcgaacg cctcccagga cgtctccagc agcagccgct gctgggggtc
     5881 catggccagg gcctcacgcg gtgagatgcc gaagaagtcc gggtcgaagt cggagacgtt
     5941 gtccaggaac ccgccggtga gcgcgtaggt cttgcccggc ttgtcggggt cggggtcgta
     6001 gagcccgtcg aggtcccagc cacggtcgtc ggggaacccg gagatcgtgt cgactccggc
     6061 gttcaccacg tcccacagct gttcaggggt ccgcacaccg cccgggaagc ggcagctcat
     6121 cgccacgatc gcgatgggct cgtcgaagga gtccgatcgg gtcggcgtga cctcggcggc
     6181 gccgccttcc tcggtgccga acatctcgcc gttcaggaac cgcgccagca ccgtgggcgt
     6241 ggggtagtcg aagaccaggc tgaccggcag ccgcagcccg gtcgccgcgc cgatccgatt
     6301 gcgcagttca acggcggtca gcgagtcgaa gccgaggtcg cggaaggcac ggtccgacgc
     6361 gaccgcgtcc gcgctgtcgt gagcgaggac atcggcggcc tgggcacgca ccagatcgcg
     6421 cagcgcggct tcgcgcttct cccggggcag ggcttccagc cggtcgtgga gttccgcccg
     6481 cccggggtcg gcgccacccg gtgtggactg cttccccgtg gccgtggtcc gcgcgccgcg
     6541 cagctcgcgg aagagggggc tgtcgacgga gtccgcttcg aagcgtgtcc agtcgatgtc
     6601 ggcgacggcg aggaatgtct cgtcgtggtc caacgcctgg tgcagtgccg aaatcgccag
     6661 ctcgggggac atggccagca tcccgagcgg ctcatctgct caccgacctc accggagacg
     6721 aggccaccgc cggcccaggc gccccagccg atggaggtgg ccggaaggcc atccgcacgc
     6781 cgctgcgacg ccagcgcgtc gagataggca ttacccgccg cgtaactccc ctgacccgga
     6841 ccacccaacg tgcccgccgc cgaagagaac aacacaaacg ccgacagatc catccccgcc
     6901 gtcaactcat gcagattcca cgccgcatcc accttcggac gcaacacccc agccgcacgc
     6961 tccaccgtca gggcgtccac gacgccgtcg tccagcacac cggccgtgtg caccacggcg
     7021 gtgagcggca actccgaagg aatcgcgtcc agcaccgcgg ccagtgcgtc acggtccgcc
     7081 gcgtcgcacg ccgccaccgt cacccgggcc ccgagctcct ccaactccgc cttcaacccg
     7141 gcggcaccct cggcatccat cccgcgacgg ctcgtcagca ccagatgctc ggcacccgta
     7201 cgcgccagcc agcgggccac atgaccaccc agcgcacccg taccaccggt caccaacacc
     7261 gaaccacccg aacgccaccc accgacaccg gtggcctcag acgcggaagc ccgcaccagc
     7321 cgcttgacga acacacccga accacgcacc gcgacctgat cctcaccgac cgcgcctgcc
     7381 agcactccgg ccagccggac cagcgcccgg ctgtccatgg cctcgggcag gtccacaaca
     7441 ccgccccagc gctggggata ctccgccccc acgatccggc ccaggcccca caccatcgac
     7501 tgcaccgggc tcaccagccg gtcggaacga cccaccgaca ccgcaccccg ggtaccacac
     7561 cacagcggag ccaccacacc cgcatcgccc agcccctgaa ccagacccac catcgcggcc
     7621 agaccacccg gcaccacacc gaacgccgga tgccgggact cgtccagcgc cagcagcgag
     7681 aacacacccg ccacgtccga cggctccacc gccacgccgt caagcgccac gcgcagccgc
     7741 tccgcaacgg cctcgcggtc atccgcggcc ccgacgacca cggagaccac atgcgcgccg
     7801 cgaccggtca agccgtccag cacggtggca gccagggtct cgtcaccaca ggcttccgga
     7861 acggccacga gccaggtgcc cgagagcgtc gactcggacg cggacgccag gggcttccag
     7921 accgccttgt aacgccagct gtccaccgtg ttctgctcgc gccgctgacg gcgccaggac
     7981 gacagcgcgg gaagcagcgc cgtcagcgac gactgccgct cctcgtcctc cacctccaac
     8041 gtccgcgcca gcgcctccag atcctcgcgc tccaccgcct cccagaagcg cgcatccacc
     8101 gcatcggcgc tcaagccgtc accggcggcc gccacctctg cggccgagag ggcgtccagc
     8161 cagtaccgct ggcgctggaa ggcgtaggtc ggcagctcga cacggcgggc acggtgtccg
     8221 gcgaacacct tccgccagtc aaccgtggcc ccattgacat ggagctcggc ggcggaggtc
     8281 aggaaccgct ccagaccacc ctcgtcacgc cgcagcgtgc ccacgaccac cgcctgtgcg
     8341 tccgcggcct ccacggtctg ctgcacggga agggtgagca ccgggtgcgg gctcacctcg
     8401 atgaacacgc cgtgtccagt gtcgagcagg gtgcgggtgg tggcctccag ctcaacggtc
     8461 tgccgcaggt tccggtacca gtactcggca tccagaccgg ccgtatccac cagctcaccg
     8521 gacaccgtcg aatagaacgg cacctccgag gagcggggtt ccagatccgc caggaccctc
     8581 agcagctcct cgcggatccc ctccacatgc gcggagtgcg aggcgtagtc caccggaacc
     8641 cggcggaccc gcacctcctc accctccagc tccgccacca tctcatccag cgcacccgga
     8701 tcacccgaga ccacgacgga acccggaccg ttgaccgcgg ccaccgagat cgcaccgtcc
     8761 caagcggcga tgcgctcctt ggcccggtcc gccgacagtc caacggacac catgccaccg
     8821 tggcccgcca gaccggcggc gatggcctgc gaccgcagcg ccaccacctt cgcggcgtcc
     8881 tccagcgaca acgcacccgc cacacacgcc gccgcgatct cgccctggct gtgacccatc
     8941 accgcatccg gctccacacc caccgagcgc cacagcttcg ccagcgacac catcaccgcg
     9001 aacaacaccg gctgcaccac atccacccga tcgaaaccgg gagcaccctc gccaccacgc
     9061 agcacctcgg tcagcgacca gtccacatac gccgacagag ccgtctcaca ctcgccgatc
     9121 gcctccgcga acaccggcga ggactccagc agccccaccg ccatgcccat ccactgcgcc
     9181 ccctgaccgg ggaacacaaa caccgaacgg ccccgcgcat cagccacgcc acgcgtcaca
     9241 cccgaggcca cctcgtcccc ggccaacgcg cccagccgct ccaggagttg ctcacggtcg
     9301 gcacccgtca ccaccccgcg gtgctcgaac accgagcgcg acgtcaccag cgagaacgcc
     9361 acagcggcgg cgtccagctc cgggcgctcg atcacgaact cccgcagccg ctcggcctgc
     9421 gcccgcaggc cctccgggct acggccggac accagccacg ccaccggacc gccgacggcc
     9481 tcggcctcgg catcctcggc cgcctcgacc tccggggcct gctccaggat cgcgtgcgag
     9541 ttggtcccgc tcacgccgaa ggacgacacg ccggcgcggc gcgggtggtc cgactccggc
     9601 caggcggtgg cctcggtgag cagcgcgatg tcgcccgccg accagtccac gtgctgtgac
     9661 ggctcatcga tgtgcagcga cttcggcaac acgccgtgcc gcatcgccat caccatcttg
     9721 atgacaccgg ccacaccggc cgccgcctgc gaatggccga tgttcgactt caccgatccg
     9781 agccacagcg gctggtccgt gggccggtcc tggccgtagg tggccagcag agcctgcgcc
     9841 tcgatcgggt cacccagcga cgtacccgta ccgtgcgcct ccaccgcgtc gacctctgcg
     9901 cccgacagcc gggcggtctt gagcgccgcg cggatcaccc gctgctggga cgggccgttc
     9961 ggcgccgtca gaccgttgga cgcgccgtcc tggttgaccg ccgaaccccg gacgagggcc
    10021 agcacctcgt ggccgttgcg ccgggcgtcc gacagccgct cgacgagcag cagcccgacg
    10081 ccctcggcga agccgaatcc atcggcgtca ttgctgaacg ccttgcactt gccgtcggcg
    10141 gacagcgcgc gctgacggct gaagtccacc agtccggcct gtgtggacat caccgtcgcg
    10201 ccaccggcga gcgccaagtc gcactcgccc tggcgcagcg cctggaccgc gaggtgcagc
    10261 gcgaccagcg acgacgagca cgcggtgtcc accgtcaccg cgggcccctc caagcccaag
    10321 gtgtaggaga tacggcccga ggccacgctg cccgcactgc cggtgccgag gtagccctca
    10381 aagccttcgg gggcgttgcc ttgcagccgg gtgccgtagt cgttgtacac aacgccgacg
    10441 aagacgccgg tccggcttcc cttcgccgac tcggggtcga taccggcccg ctcgaacgcc
    10501 tcccatgagg tctccagcag cagccgctgc tgcgggtcca tcgacagcgc ctcacggggc
    10561 gagatcccga agaacgccgg gtcgaactgg tcggcgtcgt agaggaagcc accgttgcgg
    10621 gcgtagtacg tgccctcgcg cgcggggtcc gggtcgtatg tcgtctcgag gtcccagcca
    10681 cggttggacg ggagcgaggc ggtggcgtcg gtgcccccca tcaccaggtg ccacagttcc
    10741 tcgggcgtcc gcaccccacc ggggaatcgg cagctcatgg agacgatcgc gatcggatcg
    10801 tcgtccgtgc gggacagggc ctcggctgat ccgcccgccg tcggtgccgc ggtggccgtg
    10861 ccctgggacc cgaggatctc cgaacgcaga tggcccgcca gtaccgtcgg gttcgggtag
    10921 tcgaaaacga gcgtcgcggg caggcgcaaa ccggtttccg cactcagccg gttgcgcagt
    10981 tccacggccg tgagcgagtc gaagcccagc tccttgaagg gccgtcccac ctcgacggtg
    11041 tccgagttcg cgtggcccag ggcggcggcc acctggatac ggatgagctc ctccagcagg
    11101 aactgctcct ggtccgcctc ggacatgctg accagtcgcc gccgcaggcg ggcggcgatg
    11161 tcgtccacgt ccgcgtctcc ggcaccggcg acgcgccgga ccgtcatccc cggtacgaca
    11221 ttgcggaaga gggcggggag ttcggcgccc tgcgcacgca gcgccgggat atccagccgg
    11281 aagagaaccg ggacgaccgc atccgagacc agggcggcgt cgaacagctc aaggccctcg
    11341 tccgtggcca gcggcagcac gcccgagcgg gatattcgct ggatgtcgtc ctcgccgagg
    11401 tgtccggtca tgccactggc ctcggcccac agaccccacg ccatcgacac acccggcagc
    11461 cctgcgcccg ccgccacgag gcgagaccat ccaggaacac attcgcagcc gcgtagttgc
    11521 tctgcccggc accacccagc acaccagtgg ccgacgagaa cagcacgaac gccgacagat
    11581 ccatccccgc cgtcagctca tgcagattcc acgcagcgtc caccttcgcc cgcaacaccg
    11641 gctcaacccg ctcacgcgtc aacgacgtca gcaacccgtc atccagcaca cccgccgcat
    11701 gcaccacacc actgagcgca aaaccctccg gcaaccccga caacaccccg gccaaagcct
    11761 caccatccgc ggcatcacac gccgcgatca ccacctcagc acccgccccc tccaactccg
    11821 cccgcaactc cgccgcaccc tcggcctccg caccacgacg cgacaacaac accagcctgc
    11881 tcaccccatg ccgcaccacc agatgccgcg acaccacacc acccaacaca cccgtaccac
    11941 ccgtcaccaa caccgcaccc gaaccaaacc cacccgacac ctcacccgac acccgcaccc
    12001 gacccagacg cggcacccgc accacacccg aacgcaccac cacctgctcc tcacccagag
    12061 ccagcacccc gggcagaacg ccaccgacac cctccacatc atcggtgtcc accagcacca
    12121 gacgccccgg gttctccgac tgcgcggacc gcactagccc ccacaccgcc gccccggcca
    12181 tgtcctccac accatcgccc gcatcgacag caccccgcgt caccaccacc aaccgctcac
    12241 ccgcgagatc ctcatccgcc acccacgccc gcacccgctc caggacctca aggacccggc
    12301 catacacctc acccaccaca tccggaccct cggaaacgac ccgcaccacc tcagtccgcg
    12361 acgccacctc acccccggcc gccacagccc caggcgcgtc cacccactcc acccggaaca
    12421 acccatcgcg cgccgctccg ccgaccgcgt tcagctgatc cgcgtcgacc gggcgcagca
    12481 ccagcgactc gaccgaggcc accccacgcc cggactcatc ccccaccagc accgacaccg
    12541 catccgaccc agcacccacc gacgccaacc gcacccgcaa cgacgtcgca cccaccgcct
    12601 ccaaagcgaa cccacgccac gagaacggca acaaactccc cgaaccaccc gcaagagccc
    12661 cactcacacc caacgcatgc aacgccgcat cgaacaacgc cggatgcaaa ccaaactgcc
    12721 ccgcccgctc ccgctccccc tccggaagcc caacctcagc aaacacctca ccatcacgcc
    12781 gccacgcacg cctcaacccc tgaaaaacag gcccatactc caacccgttc tccgcagccc
    12841 gcacatactc acccgacaca tcaaccaact cagcccccac cggaggccac acaccaaagt
    12901 cgtactgtgt ctcggagctg ggcacggccg aaccgagcac accatgggca tgccgcaccc
    12961 atgccgcgcc atcgccgtcc gcctcctccc gcgagtacac gctcacctca cggaagccgg
    13021 aagcgtcggc ctcccccacc tcaacctgga ggtgtacgcc acccttctcg ggcacgatca
    13081 gcggcgcttc gatgaccagt tcctcgaccc ggccgcagcc gacctgatcg cccgcccgta
    13141 ccaccagctc gacgaacgcc gtccccggca gcagcatcac cccgtgtacg gcgtgatccg
    13201 ccagccactc atgcgtggcc aacgacaacc gcccactcag cagcaccccg ccaccactcg
    13261 ccaacgacac caccgcaccc agcaacggat gccccagcga acccaacccc accgaaccca
    13321 catcacccac accgcgggag cgtcaagcca gaagcgctcg tgctggaagg cgtaggtcgg
    13381 caattcaacg cggtgggcgc cgtgtccggc gaacaccttt tgccagtcaa cgcgcgcccc
    13441 gctgacgtga agctcagcgg cggaggtcag gaaccgctcg gccccgccct catcgcgccg
    13501 tagtgtcccc acgaccacgg cccgcgactc agcggcctca actgtctgct gcaccggaag
    13561 ggtcagcacc ggatgcgggc tgacctcgat gaacacggtg tggcccgcgt cgagcagcgt
    13621 gcgagtcgtg gactccagct caaccgtctg ccgcaggttc cggtaccagt actcggcgtc
    13681 cagctgagcc gtgtccacca gctcaccggt caccgtcgag tagaacggca cctccgagga
    13741 ccgcggctga aggtccgcca gaaccctcag cagctcctca cgaatcccct ccacatgcgc
    13801 ggaatgcgag gcatagtcca ccggaacccg acggacccgc acctcctcac cctccagctc
    13861 cgcaaccatc tcatccagcg cgtccgggtc accggccacc acgaccgaac ccgaccattg
    13921 accgccgcca ccgaaatcgc cccaccccac cgggcgatac gctcctccgc tgctccgcgg
    13981 acaaccgacc gacaccatgc caccacgacc agcaagcccc accgcgatcg cctgcgaccg
    14041 caacgccacc accttcgcgg catcctccag cgacaaccca cccgcccaca cgccgcagca
    14101 atctcaccct gactatgacc catcaccgca tccggctcca cacccacgaa cgccacaacc
    14161 gcgccaacga caccatcacc gcaaacaaca ccggctgcac cacatccacc cgatcaaaac
    14221 caggcgcacc ctcaacacca cgcaacacac ccgtcaacga ccagtcacat acgccgacag
    14281 cgccgcctca cactcaccaa ccgcctccgc gaacaccggc gaggactcca acaaccccac
    14341 tgccataccc acccactgcg ccccctgccc cgggaacaca aacaccgaac ggccgggagg
    14401 cgcgctctcg cccaccacca cgcccggaag agcggacttc tccgcgacgg cgcccagacc
    14461 ggacagcaac tcgtcccggt cccggcccac cagcaccgcg cggtgatcca gcaccgaccg
    14521 ggtcatcacc agcgaccgcg ccacatcggc ggcgcccagc tccgaacgcc cggccacgta
    14581 cgcccgcagc cgctcggcct gggcccgcag cccctcggca ccgtggcccg acaccaccca
    14641 ggccaccgga ccgtcggcga cctcgggctc agcgtccccg gccgcctcgg cctccggggc
    14701 ctgctccagg atcacatgcg cgttcgtccc gctcacaccg aacgaggaca caccggccct
    14761 gcgcggctca cccgtctccg gccacggggt cgactcggtc agcagcgaca ccgcccccgc
    14821 cgaccagtcc acgtgctccg acggctcctc tacatgcagg gtcttcggca gcacaccgtg
    14881 ccgcatcgcc atcaccatct tgatgacgcc acccacaccc gcggccgcct gcgtgtgacc
    14941 cacgttcgac ttgaacgagc ccagccacaa cggccgatcg gctccggcgc gctccttgcc
    15001 gtaggtggcc agcagcgcct gtgcctcgat ggggtcgccc agcggtgttc cggtgccgtg
    15061 tgcctccacc gcgtcgacat ccgccgcgga caggccggcg ttgcgcagcg cgtcgcggat
    15121 cacccgctgc tgcgaggggc cgttgggagc cgtcagccgg ctgctcgccc cgtcctggtt
    15181 cacggcggcg ccccgtacca cggccagcac ctggtgtccg ttgcgctggg cgtcggacag
    15241 tcgctccagc agcagcacac cggcgccctc ggaccatccg gtgccgtcgg ccgcgttcga
    15301 gaacgacttg cagcgtccgt ccacggcgag tccgcgcaac cggctgaact cgatgaacac
    15361 ccctggtgtc gccatcatgg ccacgccacc ggcgagcgcg agcgagcagt cgcccttgtg
    15421 gagcgcctgg acggccagtt ggagcgccac gagcgacgag gagcatgccg tgtccacggt
    15481 cacggcgggg ccttcgaagc cgaaggtgta ggagatacgg ccggaggcga cgcttccggc
    15541 gctgccgttg ccgaggtggc cttcgaggcc ctcgggtatg gact
//
