LOCUS       NZ_CP019458            23456 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 chromosome, complete
            genome.
ACCESSION   NZ_CP019458
VERSION     NZ_CP019458.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10005572
            Orig. end                         :: 10029028
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019458.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23456
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="46"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..23456
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23456
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:>23456](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>23456
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            947..2968
                     /locus_tag="BV401_RS40945"
                     /old_locus_tag="BV401_41020"
     CDS             947..2968
                     /GO_component="GO:0044423 - virion component [Evidence
                     IEA]"
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959215.1"
                     /locus_tag="BV401_RS40945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41020"
                     /product="phage tail protein I"
                     /protein_id="WP_079260198.1"
                     /transl_table=11
                     /translation="MTCSPHPATFRLLDAYVGWDRQEAYGIVGFDAPAGLRLAHRGADP
                     EGPTRDRLLPWFPDPRLAPGCGPCGWYLLVPGERRLLRRDGCGGAFTPLWPPDRGPGPP
                     HRPVSVAARGHRLAVVESGRVLVWRREGEQLAGVIPAERPRWAALGPGDEVLVACQGST
                     DLRRFDSTGGFRGVLRTGVPGEIIGLRTGPERTVWLLTDDGGRLGVHRGGHGRPFRPVT
                     ADELAAALPPSTLTSADGNGFCLGEKGPEGPETSCFTWQGRPRDPAPPATDAYETGGSY
                     LTALIDSGISRCRWHRVRVDADVPAGTAVAAEIVVSEDGRYDESDWQLPAPGAADFLVD
                     QPPGRFIRLRLRLSGDGGSTPVVRRIRLDFPRVTSADLLPPAFREDPAADDFTERFLSL
                     FDATLAQLDRVIERYPSLLDPAGVPDRALPWLAGLLGLSFEAGWDARTRRALLAAAPEL
                     YRRRGTPWALREAVRIVFGVTPVVDELAADRRWAWLRQAAGALGAERQQGGEGEQGQEP
                     GPGRGRETGPGQGLGAVRLFGRSASRFRVGGTALGAAPLRAFGTPDSDPFTAHAHRFRL
                     LLPAGSADETALRRLVERQAPAHTVGSVRTGGAGFVVGSRSTVGVDTAFVPLPVPVLGG
                     AHPVRLGRDGVLRPGPRGLRRGVGVGVVSAVGMHTQVS"
     gene            2981..4237
                     /locus_tag="BV401_RS40950"
                     /old_locus_tag="BV401_41025"
     CDS             2981..4237
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057296.1"
                     /locus_tag="BV401_RS40950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41025"
                     /product="hypothetical protein"
                     /protein_id="WP_079260199.1"
                     /transl_table=11
                     /translation="MTGTGPSRTEEFDAPPLRRLRYFHGQMLGARDFQREQEYHREKLR
                     LRMRCLLGYGVVCGLHVEPVRRDEDDCPPADAVEGSARPGESAEEGGTEPERTRRGAKV
                     RITPGLGVDCEGNEVVVRGGCEIDLWKALPRHERDTDTVWVGVEYAERPVEPTRAVYND
                     GCADTSDCEFGWTEECYTVRVTGCEPPEDERCDTCCSPCEHTVLWLARIDRVDWYEPVR
                     RDRIHMNVRRPFGRHLPTVITGINWIHGHTYTIDEAKDLLGTLDEDGGLVVRFSADVRS
                     DTLRPGVVEIQVIEGGSGRNASTWYMGGAFAEPDPESEDGHEFTRRFRYRQTTRETLQD
                     GDRVLITVRAAFLLDRCCRPVDGTHVGGRVPLIHTGATVSAEHGEECCDLPPSGIGPWT
                     SGTGAGGDVFESWFFVKER"
     gene            4240..6354
                     /locus_tag="BV401_RS40955"
                     /old_locus_tag="BV401_41030"
     CDS             4240..6354
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057297.1"
                     /locus_tag="BV401_RS40955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41030"
                     /product="hypothetical protein"
                     /protein_id="WP_087684355.1"
                     /transl_table=11
                     /translation="MRTDCGCGCGGDATRTSAFVRPRFFAGQLLTEDDLSLLVEYTTAK
                     ARLHNRSLYGPGVICGLGVTCDPCGGGTVAVHPGHALDCAGNDIVVPCTERVDVPALVR
                     ERRISALGVDCGESRCDDDGDSGRRYGLYARYRELPVEPVAPYATEEPCPSPGCVPSRI
                     QEGFQFVVKCDDFEDHRHNPGTRLLTTLGDLTRADRARTRDRRLGFYTDALTVASLGTG
                     RAFRFDAADARRYATALAWLRANAGGEGPPAPPTVREMTENVRALAAAIARYDTYDPAG
                     QTQLGKDYPDLATVRDARGVLGTACARLGGADMEAAWPDPLRRGIAHAVVTETAARVVP
                     ERGDPDAPLEVRMLAQGTPLGHALRVEFRADLGLIREWLLCRLDQATDLADCALRQDIA
                     AVDVPPPLPAPPPDSTEKATVAEVQQIAEAAAALGGAVRRFLTDAACATLNPPCGDSAD
                     TDVLLAHLELDGCDVVRVCSATREQVLPGGSAYGEWLPKLYRLRELAERVCCQPVPRHQ
                     KPTLPSEGPVARPYADDLLGDWPRTGDLEEMLSLLLTRAPGETPPKALHEQVYTTPSEV
                     TDSMQELARLRTQVADLTAAVEGLRAQLGSARTQVTHLEEQVPERLGSRLAELEGAPDR
                     AAGQRPERDQAQGSDRAQDQPQDRAQDQPSAQAQPSDQAQAPDPAERQPAKPPARRSRS
                     PRTRKPGETP"
     gene            6351..7487
                     /locus_tag="BV401_RS40960"
                     /old_locus_tag="BV401_41035"
     CDS             6351..7487
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173090.1"
                     /locus_tag="BV401_RS40960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41035"
                     /product="hypothetical protein"
                     /protein_id="WP_079260200.1"
                     /transl_table=11
                     /translation="MTGPLRPAFHEGQVLAAADLSATVEYARGGAARHARHLHEWGIVE
                     GLGLVTEPRTDPLTGVRHVEVSVSAGIAVDGTGREVVVTEPVVLRESDFEEVNGADQPT
                     DEPYPVFLTAADRESARTPGPVSCTGSATGTRVEESYQILFGRLGDERLAAEQRPPAIG
                     APPADPPARWLVLLGYVRWADGHFSGVETMARGVAARFAGVRADTVSARSGALTLRTGP
                     ETREGEPALVLSGGDTPNLVFGLYQGGGAVSPLMTVAANGNLSIEGSFGGRMPAGSTLV
                     TSGTATDGMLLPLPSGITPEQVADGRVVLHVHLTPHPPPLAETALFSAVETTVDGDRRV
                     RCRVRVYNPAVNWKQPVEQPGAVDFLVLATVAATNGGG"
     gene            7490..8020
                     /locus_tag="BV401_RS40965"
                     /old_locus_tag="BV401_41040"
     CDS             7490..8020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057299.1"
                     /locus_tag="BV401_RS40965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41040"
                     /product="hypothetical protein"
                     /protein_id="WP_079152782.1"
                     /transl_table=11
                     /translation="MALSVVYAVDTGHVVGALALTGTDAPADVAALVGRALPLRVSLGE
                     GRTATLPLNARDLAVAAVDDEPAALADPLAFGVELTAEGKPKPALVRLPSWTEGIALAT
                     DGLTVTVKVAVARTTPVVVLVSDEQDTHVLTGEIPAQQTQVKLPVTLVADSVHGVLVLV
                     AGWAGRLGKEKAT"
     gene            8017..9906
                     /locus_tag="BV401_RS40970"
                     /old_locus_tag="BV401_41045"
     CDS             8017..9906
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057300.1"
                     /locus_tag="BV401_RS40970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41045"
                     /product="hypothetical protein"
                     /protein_id="WP_193525029.1"
                     /transl_table=11
                     /translation="MSAPTAPTADGTDGIGGLGGLGDSGEAGEITVHRCTVTVVRCGGW
                     SWGPEPRGLVRHVVDALPELLAEHFAERLAADGPDMEITEALTVTVRPGRTGRYGWSGG
                     ASGGGPPVEVHFAPVAMVEVPGDAPADGGGSFEESFAAAPDPWTAPGAAALFAELAERG
                     ELDALLALLPDVSVRAYLLALLGVDDTAAARLLAELVRPVLAGSSPAGPHGGAARPGPV
                     EPLPEPLPERLRAVVAGADAADLPRLLADFLASADRAEAVRLARPPADPHAPNTDERPG
                     AAGRSAGASAAAGARTTGEVQVWSALPFLLTGPLARIGYLDAIGPALAGVELAEDAPLF
                     AAALACKVLGETARGWRRAERDGEAAAAFAGLPPPLAEERLADFARRAGPALPVLDGVL
                     ALAVCRGHDPADPLLLTGADDGLLLIDAHGMFPIAWTPEATALLPYWHSCGRPPVLLCD
                     GPLPPGTLRELASAGVPFLTAVRPLRGDPVARLPWRTPLWAAEGAAPDIRLAAELPAHT
                     QRCTALVTALVTERRAVPLARDGALERTVTLAAALGLATIAWTLWRDRETPDPLSALAR
                     FADLAATVRYERAAVRVRVPMGRRHADLQRGGLLADVPDVAWLGGRTLTFSAG"
     gene            9912..12014
                     /locus_tag="BV401_RS40975"
                     /old_locus_tag="BV401_41050"
     CDS             9912..12014
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173087.1"
                     /locus_tag="BV401_RS40975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41050"
                     /product="ATP-binding protein"
                     /protein_id="WP_079260201.1"
                     /transl_table=11
                     /translation="MGEPAVEHLRIRLAGLHRALRAAVERQARLAARLTRPDLTPYCVT
                     DEQVDVLLGEVHAFTDTMAEPYAPGQPEPEAERDLRRRASAGGTALPLDALAARFGLTR
                     AEQDALLLAAAPELDRGYERIYAYIVDNLNRRLPSVELLIAVGANSAAARLALRRSLGP
                     AAPLRRYGLLREHGEAAVELAQELIPAPGVLDFLLGWGGDVGLLGHDPGEVAPPEPRVL
                     SPYLSSAPLTRLGRALGAGDLDLAGLWGCPPDGQLDAVQALARSAGAPLRTLTADPEAD
                     LRTAAVLGAVLWIPTDDLHGEPQRPTADAVSAALLRSRVPVCLTGLKPWRPAGLLAARA
                     YAELTVPVPGFTDRRAMWSAALPDLNGTLLEDLAVRYRMSGGELRAVAAVADAGARLAG
                     NGHPEPVAAHVEPAIATVTRGRGGGAVHSITPRRTVADLVLPDVQFRQILEIASAFRAW
                     PRIAESWGFARRSGHGGVKALFTGEPGTGKTMSAEIVTGMLGLELLKVDLAQVVSKWVG
                     ETEKNMETAFRQAEESHAVLLFDEADALFGKRGEVKHGTDRYANLEVGYLLQRLEASDG
                     LVILTSNLKDNIDPAFTRRFHFVVHFPRPAAAERRRLWRLAFPEEAPLAPDVDVDALAR
                     LDMTGAAIAAAARTAALAAADGGGDTIAMRHVVRGVARQFQREARLLRPAELGPHAHLL
                     DNASQG"
     gene            12020..12307
                     /locus_tag="BV401_RS40980"
                     /old_locus_tag="BV401_41055"
     CDS             12020..12307
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720935.1"
                     /locus_tag="BV401_RS40980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41055"
                     /product="hypothetical protein"
                     /protein_id="WP_079260202.1"
                     /transl_table=11
                     /translation="MLPTEPPLSLHRLLAPVPPARPQETAVATHQVPAAAPAPPAAQPP
                     TAVERLLAGQDQLGNAAVAGAAARTSPVVPQPAGAVVVLKPKAAQPPASP"
     gene            complement(12286..12951)
                     /locus_tag="BV401_RS40985"
                     /old_locus_tag="BV401_41060"
     CDS             complement(12286..12951)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173085.1"
                     /locus_tag="BV401_RS40985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41060"
                     /product="hypothetical protein"
                     /protein_id="WP_079260203.1"
                     /transl_table=11
                     /translation="MTSDAVDRLRAEAARDDYASMARLARALYGMGLGPHEVLHQCYGV
                     AFPQEVFIIAEGGLWRLRLLALFTNQPWQLAVPPDRGGPAAEPDGLIDTELRLLAGDLD
                     LMPLVRIPAADPGREDRIVCYRLGELRAGRSTVFRLFESSAAEDALACGGSLLEVLHTE
                     HTASVRRLEKELRSPSNWGAGSVDDDEVDRAYASLERVEELQRQVAERLAEGQGDAGG"
     gene            complement(12948..17390)
                     /locus_tag="BV401_RS40990"
                     /old_locus_tag="BV401_41065"
     CDS             complement(12948..17390)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057304.1"
                     /locus_tag="BV401_RS40990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41065"
                     /product="hypothetical protein"
                     /protein_id="WP_237288170.1"
                     /transl_table=11
                     /translation="MDRAETGPAATAPEAAPNATPEAESRPAPDATPDAESRPAPDAAP
                     EAKARPGPDADPKFTTLKKDVRSKKRAVASSHPPPRAEAGAAQDAARPPKDDEEAQGKT
                     ANAEKMNEAKPKDFDKDAFIRAVEKAIAEKAPKNLDEADKFADSGKADEVRAEVHGKVG
                     EGTSDSAQQIATTTAAPPDTSAAVPKKVVPLAPDRPPGTPGTPDPANAVPDKLPPSATD
                     LSAGPDKLNRRMTDAQVTEGQLKKSNEPAFKSALNEKKAAERHSAVAPGRMRGHEKKEL
                     NAATARARRLGAASMGAMGAQRVRTGQRVGAGKTGAKGRDEDKRAQVTTLLQGVFDTMK
                     KDVEAILDGLDKLVDDQFGRGEKAARDAFTAEHQRKMDEYKDRRYSGVTGKLRWVRDKF
                     AGLPAEADKIFEEARDSYVRRMRQVISDVADTIGAELNRAKRRIAQGRTELREAVRGLP
                     ADLRSIGQQAAAEFTDRFDELTQSVDDKGTQLVDTLATKYTDALRSVDDEIAAEKEKNK
                     GLVAKAVDAVKAVINTILELKRLLLSVLAKAASAVMLILKDPIGFLRNLVSAVGAGLRQ
                     FLRNIGRHLQQGILSWLLGKTAEAGVALPSRFDTQGVLRMLASLLGLTWQSIRARIVRK
                     VPKMEPAVSAAETAVPLVAEVRKRGVAGMWDDLKTRVGDLRKDLLDKVIAYVTPTIVVA
                     GIMWVISLLNPASAFVRAVKLIIDIVRFIVTRARQIVEFVNAVLDAVIAIAGGGSGGVP
                     GLIEQALARSIPVLLGVLAAILGVGGIASRVKGIVQAMAKPVNRAVDWVIDKIVGLVKK
                     LWSRIKPKSDKTKPKPKRRPDRRRPGGPRRRRRPDQRRRPDRRGPKRSGGPKKKRPDKR
                     SWKDIQRALDAALREATRLLNAEAATEESIREGLPAIKRRHRLTRIELKKKGSDTYAVM
                     VAINPSKSTSYKELFPYRIDRAQGKFPIKRHPHAVVQLQPIDQPIEGNDRWIGFVVNMA
                     AIPGEITKNPTVATRYLDKAWQGTGALHAQDMAAARTAVVIGINSFERLNPQEGDAIGG
                     AINSVGRKPELLMAVFGFVWTPRWVKGKRNRKVGIEEVRAAYQQLEASNKRRAEANEKG
                     LRDKGALPYGIFRDEVIRSEYTKSAVNILKDVNQQVHIVSQDADTGVAAISGVGVLRAY
                     EKVLTEMGVHPLLTIGGYHFDDFDWGRKADRRAKQLTRLANELDRAIRVGIAKKYPQML
                     YPTEPNLLIKAWDHQEGRVSGIFQDARGLALLEVQGLLFGARGAEGRAMRNALMKAFGT
                     DFSVAYAPDASTGTSPLPGDEARGLTVTPLAVRRAAQGKMRVRGGEETLRTAHRMYALI
                     IQSQSNASARTLAREFTRATPGLDETAQRLLQNKIFSYVEDTAMLMADNPSLTGGNPAV
                     RALKERLDADVEALNRLQAVGEDPEFQRAVDKAHETTQEIISAMTASQLAKLWKNISLA
                     LDAATKKPSEGRGRRGGRR"
     misc_feature    complement(14739..14741)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17795..17810)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     misc_feature    17806..17821
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     misc_feature    complement(18135..18148)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.58"
                     /tool="antismash"
     misc_feature    complement(18139..18154)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.45"
                     /tool="antismash"
     misc_feature    complement(18141..18150)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.04"
                     /tool="antismash"
     misc_feature    18437..18451
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.71"
                     /tool="antismash"
     misc_feature    18472..18487
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            18516..19361
                     /locus_tag="BV401_RS40995"
                     /old_locus_tag="BV401_41070"
     CDS             18516..19361
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BV401_RS40995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41070"
                     /product="cytochrome P450"
                     /protein_id="WP_232564907.1"
                     /sec_met_domain="p450 (E-value: 7.2e-23, bitscore: 79.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIERIVHEQLDDLEKAGPGADLVDVFTESVPSRVMCEMIGVPESE
                     RKSLQRHVETLGRLSSTVPEALAAVSGMSGFLARFVPTRMDDPRDDILGDLIRGGQLTE
                     QELMGMTATLITGAMDTTGNMLAMGIFTLLEHPDQLAKLREDPELMGAAVEELLRFLTI
                     SHLGASRWALEDVEFAGQTIKKGEVVTVALPAVNRDPERYDNPDQLDIGRTDHGHLALG
                     HGVHQCLGQHLARTILRVGYEALFDRFPTLQLAVPSEEIQMRDDFVHYGPRSLPVTWDD
                     "
     gene            19538..19744
                     /locus_tag="BV401_RS41000"
                     /old_locus_tag="BV401_41075"
     CDS             19538..19744
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491075.1"
                     /locus_tag="BV401_RS41000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_41075"
                     /product="ferredoxin"
                     /protein_id="WP_069860755.1"
                     /transl_table=11
                     /translation="MRITADREACCAAGQCALIAPDLFDQSDDDGTVVLLDARPDAGRL
                     DALREVVSRCPTGAIRIEEDPGA"
     gene            20001..>23456
                     /locus_tag="BV401_RS41005"
                     /old_locus_tag="BV401_41080"
                     /pseudo=""
     CDS             20001..>23456
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (38-464). E-value:
                     1.1e-186. Score: 612.8. Matches aSDomain:
                     nrpspksdomains_BV401_RS41005_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (573-871). E-value: 6.7e-113.
                     Score: 368.9. Matches aSDomain:
                     nrpspksdomains_BV401_RS41005_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (938-1083). E-value: 3.1e-52.
                     Score: 169.2. Matches aSDomain:
                     nrpspksdomains_BV401_RS41005_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057309.1"
                     /locus_tag="BV401_RS41005"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="BV401_41080"
                     /product="type I polyketide synthase"
                     /pseudo=""
                     /sec_met_domain="mod_KS (E-value: 5e-233, bitscore: 772.4,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 6.3e-93, bitscore:
                     309.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9e-111, bitscore: 368.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAASNQNKAVEALRKSFKEIERLRRQNRQLISSATEPIAIIGMA
                     CRFPGGVNSPEALWQLVADGADGISPFPTNRGWDVEGIYNPDPDHPGTSYVREGGFLHD
                     ADQFDSAFFGISPREALAMDPQQRLLLETSWEVLERAGIDPASLRGSQTGVFTGAMHTT
                     YASEAAQIPDEIEPYLHNGATTSIASGRVSYTFGFEGPALTVDTACSSALVALHLATQA
                     LRQGECSMALVGGATVMVSPKGFVTFSRQRGLAVDGRCKAFADSADGTTWSEGIGVLLV
                     ERLSDARRNGHQILAVVRGSAVNQDGASNGLTAPNGPSQRRVIRQALENCELTTSQIDA
                     VEAHGTGTTLGDPIEAQALLATYGQDRPEGRPLWLGSLKSNLGHTQAAAGVAGVIKMVM
                     AMRHGVLPKTLHVDAPSSHVDWSEGQVELLAEARPWPETGEPRRAGVSSFGVSGTNAHV
                     ILEQAPEVEADTEAEEPAGGGVAGPVAWAVSGKSDAALRAQAERLREYVAERSELSAAD
                     VALSLATTRAAFEQRAVVIGTSRQELIERLEAVAEGAELPGVVHGSDAETPGRSVFVFP
                     GQGAQWVGMAVGLLESSPVFAEAIGECEAALSAYVDWSLTGVLRGVEGAPGFDRVDVVQ
                     PVLFAVMVSLARLWRSVGVEPDAVMGHSQGEIAAACVAGGLSLEDAAKVVALRSQAIAV
                     GLAGRGGMVSVGLSAEQAEERIARWGGAISVAAVNGPGSVVVAGDPDALDEMVAELEGE
                     EVRVRRVPVDYASHSAHVEGIREELLRVLADLQPRSSEVPFYSTVTGELVDTAQLDAEY
                     WYRNLRQTVELESTTRTLLDAGHTVFIEVSPHPVLTLPVQQTVEAAESRAVVVGTLRRD
                     EGGAERFLTSAAELHVSGARVDWQKVFAGHGAHRVELPTYAFQHERFWLDAPAGVGDVG
                     SVGLGSLGHPLLGAVVSLASGGGVLLSGRLSLATHEWLADHAVHGVMLLPGTAFVELVV
                     RAGDQVGCGRVEELVIEAPLIVPEKGGVHLQVEVGEADASGFREVSVYSREEADGDGAA
                     WVRHAHGVLGSAVPSSETQYDFGVWPPVGLSWLMCRVSMCGLRRTGWSMGLFFRG"
     aSDomain        20115..21392
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS41005_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.10E-186"
                     /label="BV401_RS41005_PKS_KS.1"
                     /locus_tag="BV401_RS41005"
                     /protein_end="464"
                     /protein_start="38"
                     /score="612.8"
                     /tool="antismash"
                     /translation="IAIIGMACRFPGGVNSPEALWQLVADGADGISPFPTNRGWDVEGI
                     YNPDPDHPGTSYVREGGFLHDADQFDSAFFGISPREALAMDPQQRLLLETSWEVLERAG
                     IDPASLRGSQTGVFTGAMHTTYASEAAQIPDEIEPYLHNGATTSIASGRVSYTFGFEGP
                     ALTVDTACSSALVALHLATQALRQGECSMALVGGATVMVSPKGFVTFSRQRGLAVDGRC
                     KAFADSADGTTWSEGIGVLLVERLSDARRNGHQILAVVRGSAVNQDGASNGLTAPNGPS
                     QRRVIRQALENCELTTSQIDAVEAHGTGTTLGDPIEAQALLATYGQDRPEGRPLWLGSL
                     KSNLGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDAPSSHVDWSEGQVELLAEARPWPE
                     TGEPRRAGVSSFGVSGTNAHVILEQAP"
     aSModule        20115..23249
                     /domains="nrpspksdomains_BV401_RS41005_PKS_KS.1"
                     /domains="nrpspksdomains_BV401_RS41005_PKS_AT.1"
                     /domains="nrpspksdomains_BV401_RS41005_PKS_DH.1"
                     /incomplete
                     /locus_tags="BV401_RS41005"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20598..20645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0001"
                     /evalue="2.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="BV401_RS41005"
                     /protein_end="215"
                     /protein_start="199"
                     /score="19.5"
                     /tool="antismash"
                     /translation="GPALTVDTACSSALVA"
     CDS_motif       21021..21065
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0002"
                     /evalue="2.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BV401_RS41005"
                     /protein_end="355"
                     /protein_start="340"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       21126..21170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0003"
                     /evalue="2.70E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="BV401_RS41005"
                     /protein_end="390"
                     /protein_start="375"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GSLKSNLGHTQAAAG"
     CDS_motif       21714..21770
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0004"
                     /evalue="4.30E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BV401_RS41005"
                     /protein_end="590"
                     /protein_start="571"
                     /score="28.0"
                     /tool="antismash"
                     /translation="VFVFPGQGAQWVGMAVGLL"
     aSDomain        21720..22613
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS41005_PKS_AT.1"
                     /evalue="6.70E-113"
                     /label="BV401_RS41005_PKS_AT.1"
                     /locus_tag="BV401_RS41005"
                     /protein_end="871"
                     /protein_start="573"
                     /score="368.9"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWVGMAVGLLESSPVFAEAIGECEAALSAYVDWSLTGV
                     LRGVEGAPGFDRVDVVQPVLFAVMVSLARLWRSVGVEPDAVMGHSQGEIAAACVAGGLS
                     LEDAAKVVALRSQAIAVGLAGRGGMVSVGLSAEQAEERIARWGGAISVAAVNGPGSVVV
                     AGDPDALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIREELLRVLADLQPRSSEVPFY
                     STVTGELVDTAQLDAEYWYRNLRQTVELESTTRTLLDAGHTVFIEVSPHPVLTLPVQQT
                     VEAAESRAVVVGTLRRD"
     CDS_motif       21885..21953
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0005"
                     /evalue="2.10E-12"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="BV401_RS41005"
                     /protein_end="651"
                     /protein_start="628"
                     /score="38.6"
                     /tool="antismash"
                     /translation="DRVDVVQPVLFAVMVSLARLWRS"
     CDS_motif       21957..22067
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0006"
                     /evalue="1.00E-19"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="BV401_RS41005"
                     /protein_end="689"
                     /protein_start="652"
                     /score="62.2"
                     /tool="antismash"
                     /translation="GVEPDAVMGHSQGEIAAACVAGGLSLEDAAKVVALRS"
     CDS_motif       22176..22214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0007"
                     /evalue="3.80E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="BV401_RS41005"
                     /protein_end="738"
                     /protein_start="725"
                     /score="10.6"
                     /tool="antismash"
                     /translation="AAVNGPGSVVVAG"
     CDS_motif       22284..22316
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0008"
                     /evalue="4.00E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="BV401_RS41005"
                     /protein_end="772"
                     /protein_start="761"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VDYASHSAHVE"
     CDS_motif       22422..22466
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0009"
                     /evalue="4.80E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="BV401_RS41005"
                     /protein_end="822"
                     /protein_start="807"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LDAEYWYRNLRQTVE"
     CDS_motif       22512..22541
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0010"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="BV401_RS41005"
                     /protein_end="847"
                     /protein_start="837"
                     /score="10.7"
                     /tool="antismash"
                     /translation="FIEVSPHPVL"
     CDS_motif       22689..22721
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0011"
                     /evalue="6.70E+01"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BV401_RS41005"
                     /protein_end="907"
                     /protein_start="896"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="VFAGHGAHRVE"
     aSDomain        22815..23249
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS41005_PKS_DH.1"
                     /evalue="3.10E-52"
                     /label="BV401_RS41005_PKS_DH.1"
                     /locus_tag="BV401_RS41005"
                     /protein_end="1083"
                     /protein_start="938"
                     /score="169.2"
                     /tool="antismash"
                     /translation="HPLLGAVVSLASGGGVLLSGRLSLATHEWLADHAVHGVMLLPGTA
                     FVELVVRAGDQVGCGRVEELVIEAPLIVPEKGGVHLQVEVGEADASGFREVSVYSREEA
                     DGDGAAWVRHAHGVLGSAVPSSETQYDFGVWPPVGLSWLMC"
     CDS_motif       22899..22973
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS41005_0012"
                     /evalue="1.10E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="BV401_RS41005"
                     /protein_end="991"
                     /protein_start="966"
                     /score="30.8"
                     /tool="antismash"
                     /translation="WLADHAVHGVMLLPGTAFVELVVRA"
ORIGIN
        1 gcaccacggc cggaaccgcg tcccggtggc gcgaggtgga gagcctggcc ggctacggcg
       61 ccgaggaccg ggtgttcacc gtggaccacg aaagcggcga ggtgaccttc ggggacggcg
      121 tcagcggcgc ggccgtcccg cccggcttcc gcaacgtccg cgccgtgcgc taccgcgtgg
      181 gcggcggcag cgccggtgcc gtggcggcgg gcgcggtgaa cggggtggtg accgcgctgc
      241 cgttcgtcac ccgcgtggcc aaccccttcc cggcctccgg cggcacggac gccgagcccg
      301 acgcggatgc catgcgccgc ggcgcggggg aactgcgggc ccgcggccgc gccgtggccc
      361 ccgccgacta cgggcagctc gccacccgcg cacccggcgc gtcggtggcc cgcgcccggg
      421 gcgtccccgg tctgcacccc gacttcgccg gggcgccgat ccccggcgtc gtgggagtcc
      481 tcgtcgtacc acccgtaccg ccgggcgacg ccccggacga accgccggtc cccaccgccg
      541 cgaccctgaa ggccgtcgcc gacttcctgt cccgcgaagc cgcccccgcc ggagtcaccg
      601 tggtcgccgc ccccgcgccg taccgccgtg tcgcggtgga gtcctgggtg gccctcgacc
      661 cggacctcga ccgggccgcc gtcctggccc gggccgggga cgcggtgcgc acctatctgg
      721 atccgctgcg cggcggggag gacggcgcgg gctggccgtt cggcggcgcg ctgcgccata
      781 cggcgctggt ccggcggctg ctggcggtcg acggggtgct ggccgtcacc cggctctcgc
      841 tcaccgtcga cggagtgcgc cgcccgccct gcaccgacca cgccctcccg ccccacaccc
      901 tcgtctggcc ggagcgcccg ctgctgatcc cggtaggaga ccggccatga cgtgctcacc
      961 gcaccccgcg accttccggc tcctcgacgc ctacgtcggc tgggaccggc aggaggcgta
     1021 cggcatcgtc ggcttcgacg ccccggccgg cctccggctc gcccaccgcg gggccgaccc
     1081 ggaaggcccc accagggacc ggctgctgcc gtggttcccc gacccgcgcc tcgcgcccgg
     1141 atgcgggccg tgcggctggt atctgctcgt ccccggcgag cggcggctgc tgcgccgcga
     1201 cgggtgcggc ggtgccttca cccctctctg gccgcccgac cgcggccccg gcccgccgca
     1261 ccgtccggtc tccgtcgccg cgcgcggaca ccgactggcc gtggtggagt ccggccgggt
     1321 cctggtgtgg cgccgagagg gcgagcagct cgccggagtg atcccggccg agcggccgcg
     1381 atgggccgca ctgggccccg gcgatgaggt tctggtggcc tgtcagggca gtacggatct
     1441 gcggcggttc gactcgaccg gcggcttccg cggggtgctg cgcaccggcg tgcccggcga
     1501 gatcatcggc ctgcgcaccg gaccggagcg gaccgtgtgg ctgctcaccg acgacggcgg
     1561 gcggctcggc gtccaccggg gcggtcacgg ccggcccttc cgccccgtca ccgcggacga
     1621 actggccgcc gcactgcccc cgtccacgct cacctcggcg gacggaaacg ggttctgcct
     1681 gggcgagaag ggcccggagg gccccgagac cagctgcttc acctggcagg gccggccccg
     1741 ggaccccgcg ccaccggcca ccgacgcgta tgagaccggc gggtcgtacc tcaccgccct
     1801 gatcgacagc ggcatctcgc ggtgccgctg gcaccgcgtg cgcgtggacg ccgatgtgcc
     1861 cgcagggacg gcggtcgccg ccgagatcgt ggtgagcgag gacgggcggt acgacgagag
     1921 cgactggcag ctgccggctc cgggagccgc ggacttcctt gtcgaccagc cacccggccg
     1981 cttcatccgg ctgcggctgc ggctgtcggg cgacggcggc tcgactccgg tcgtacgccg
     2041 gatccggctg gacttccccc gggtcaccag cgccgacctg ctgccgcccg ccttccgcga
     2101 ggaccccgcg gccgatgact tcaccgagcg gttcctgtcg ctgttcgacg ccacgctcgc
     2161 ccagctcgac cgggtcatcg agcggtatcc ctcgctcctc gacccggccg gtgtcccgga
     2221 ccgggcgctg ccatggctgg ccggtctgct gggcctgtcg ttcgaggcgg gctgggacgc
     2281 ccgcacccgg cgcgcgctgc tggccgccgc cccggagctc taccggcggc gcggcacacc
     2341 gtgggcgctg cgcgaggcgg tgcgcatcgt gttcggggtg accccggtcg tggacgagtt
     2401 ggcggcggac cgccgctggg cgtggctgcg ccaggccgcc ggagcccttg gagcggaacg
     2461 gcaacaggga ggagaagggg aacagggaca ggagccgggg ccggggcggg ggcgggagac
     2521 cggaccgggc caagggctcg gcgccgtacg gctgttcggc cggtcggcga gccgcttccg
     2581 ggtcggcggc accgcgctgg gcgcggcgcc actgcgcgcg ttcggcacgc cggacagcga
     2641 cccgttcacc gcgcacgcac accggttccg gctgctgctg cccgccggat cggcggacga
     2701 gaccgcgctg cgacggctgg tggagcggca ggcgcccgcg cacacggtgg ggtcggtacg
     2761 caccggcggc gcggggttcg tggtcggttc gcggtccacg gtcggcgtgg acaccgcgtt
     2821 cgttccgctg ccggtgcccg tactgggcgg tgcgcacccc gtgcggctgg gccgcgacgg
     2881 ggtgctgagg ccgggaccga gagggttgcg ccgaggggtg ggcgtgggag tcgtctccgc
     2941 cgtcggcatg catacacaag tgtcgtgaga ggacggggcg atgaccggga caggaccatc
     3001 gaggaccgag gagttcgacg cgccaccgct gcgccggctg cggtacttcc acggccagat
     3061 gctgggcgca cgggacttcc agcgagaaca ggagtaccac cgcgagaagt tgagactgcg
     3121 catgcgctgt ctgctcggct acggcgtggt gtgcggcctg catgtggaac cggtgagacg
     3181 ggacgaggac gactgtccgc cggccgacgc cgtcgaaggg tccgcgcggc ccggggagag
     3241 cgcggaggag ggcggtaccg agccggagcg cacccggcgc ggggccaagg tgcggatcac
     3301 tcccgggctc ggcgtggact gcgagggcaa cgaggtcgtg gtgcggggcg gctgcgagat
     3361 cgacctgtgg aaggcgctgc cccggcacga acgggacacc gacaccgtct gggtcggcgt
     3421 cgagtacgcc gagcggcccg tcgagcccac ccgcgccgtc tacaacgacg gctgcgcgga
     3481 cacctccgac tgtgagttcg gctggaccga ggagtgctac acggtccggg tcaccggctg
     3541 cgaaccgccc gaggacgagc gctgtgacac ctgctgctcc ccttgcgagc acacggtgct
     3601 ctggctggcc aggatcgacc gcgtggactg gtacgagccg gtgcgccgcg atcggatcca
     3661 tatgaacgta cgccgtccgt tcggccgcca tctgcccacg gtgatcaccg gtatcaactg
     3721 gatccacgga cacacctaca ccatcgacga ggccaaggac ctcctcggca ccctggacga
     3781 ggacggcggg ctcgtggtgc ggttctccgc cgacgtacgc tccgacacgc tgcggcccgg
     3841 tgtagtggag atccaggtga tcgagggcgg cagtggccgc aacgcctcca cctggtacat
     3901 gggcggcgcg ttcgccgaac cggaccccga atccgaggat ggccacgagt tcacgcggcg
     3961 gttccgctac cgccagacca cccgcgagac gcttcaggac ggcgaccgcg tactgatcac
     4021 cgtccgtgcc gcgttcctcc tcgaccgctg ctgccgcccg gtcgacggca cccacgtggg
     4081 cgggcgcgta ccgctcatcc acaccggtgc gacggtgtcg gccgagcacg gcgaggagtg
     4141 ctgcgacctc ccgccctcgg gcatcgggcc ctggacgtcc ggcaccggag cgggcgggga
     4201 cgtcttcgag agctggttct tcgtgaagga gcgctgatca tgcgaaccga ctgcggatgc
     4261 ggctgcggtg gcgacgccac ccggacctcc gccttcgtgc gtccccgctt cttcgcaggg
     4321 cagctgctga ccgaggacga tctcagtctg ctggtcgagt acacgacggc gaaggccaga
     4381 ctgcacaacc gctccctcta cgggcccggc gtcatctgcg gcctcggcgt cacctgcgac
     4441 ccgtgcggcg gcggaaccgt ggcggtccac cccggacacg cgctggactg cgccgggaac
     4501 gacatcgtgg tgccctgcac cgagcgggtc gacgtaccgg cactggtgcg ggagcggcgc
     4561 atcagcgccc tcggcgtgga ctgcggcgaa agccgctgcg acgacgacgg cgacagcggg
     4621 cggcgctacg ggctctatgc gcgctaccgg gagctccccg tcgaaccggt ggcgccgtac
     4681 gccaccgagg agccctgccc ctcaccggga tgtgtgccct ccaggatcca ggagggcttc
     4741 caattcgtcg tcaagtgcga tgacttcgag gaccaccgcc acaaccccgg cacccggctc
     4801 ctgacaaccc tcggcgacct cacacgcgcc gaccgggccc gcacccgcga ccggcggctc
     4861 gggttctaca ccgacgccct gaccgtcgcc tcgctcggca cgggccgggc cttccgcttc
     4921 gacgccgccg acgcgcggcg gtacgccacc gccctcgcct ggctgcgcgc gaacgcgggc
     4981 ggggagggcc cgcccgcccc gccgacggtc cgtgagatga ccgagaacgt ccgcgcgctg
     5041 gccgccgcca tcgcccggta cgacacctac gacccggccg ggcagaccca gctcgggaag
     5101 gactaccccg acctcgccac cgtgcgggac gcccgcggtg tcctgggcac cgcgtgcgcg
     5161 cggctcggcg gcgccgacat ggaagcggcg tggccggacc cgctgcgccg tggcatcgcc
     5221 cacgccgtcg tcaccgagac cgcggcccgc gtcgtaccgg agcggggcga cccggacgca
     5281 ccgctggaag tgcgcatgct ggcccagggc acaccgctcg gacacgcgct gcgggtggag
     5341 ttccgcgcgg acctcggtct gatccgggaa tggctgctgt gccggctgga ccaggccacc
     5401 gacctcgccg actgcgcgct gcgccaggac atcgccgccg tcgacgtacc gccgccgctg
     5461 cccgcaccgc cgccggacag caccgagaag gcgaccgtcg ccgaggtgca gcagatcgcg
     5521 gaggccgcgg cggcactggg cggcgcggtg cgccggttcc tgaccgacgc ggcgtgcgcc
     5581 accctcaatc cgccgtgcgg cgacagcgct gacaccgacg tcctgctcgc acacctggag
     5641 ctggacggct gcgatgtcgt ccgggtctgc tcggccaccc gggagcaggt gctgccgggc
     5701 ggatcggcgt acggcgagtg gctgcccaag ctctaccggc tgcgggaact cgccgagcgc
     5761 gtgtgctgtc agccggtgcc gcgccaccag aagccgacgc tcccttccga gggcccggtg
     5821 gcccgcccgt acgcggacga cctgctcggc gactggccgc gcaccgggga cctggaggag
     5881 atgctgtccc tgctgctgac ccgcgcaccc ggcgagacac cgcccaaggc actgcacgaa
     5941 caggtctaca cgacccccag cgaagtcacc gacagcatgc aggagctcgc ccggctcagg
     6001 acccaggtcg ccgatctcac cgccgcggtc gaggggctgc gcgcccaact gggcagcgcc
     6061 cggacgcagg tgacccacct ggaggagcag gtgccggaac ggctcgggtc ccgcctcgcg
     6121 gagctcgaag gcgcaccgga ccgagcggcg ggccagagac cggagcggga ccaggcccag
     6181 ggctccgacc gggcccagga ccagccccag gaccgggccc aggaccagcc ttcggcccag
     6241 gcccagcctt cggaccaggc ccaggctccg gaccccgcgg agcggcagcc cgccaagccc
     6301 ccggccaggc gcagccggtc gccccggacc cggaagcccg gtgagacgcc atgacgggcc
     6361 cgctgcgccc cgccttccac gaaggccagg tgctggccgc cgcggatctg tcggccacgg
     6421 tggagtacgc gcgcggcggg gccgcccggc atgcgcggca tctgcacgag tggggcatcg
     6481 tcgaagggct cggcctcgtg accgagcccc gcaccgaccc gctgacgggc gtccgccatg
     6541 tcgaggtgag cgtctcggcg gggatcgccg tcgacggcac gggccgcgag gtggtcgtca
     6601 ccgagccggt cgtgctgcgc gagagcgact tcgaagaggt caacggcgcc gaccagccca
     6661 cggacgagcc ctacccggtc ttcctcaccg cggccgaccg ggaatcggcc cggacccccg
     6721 ggccggtctc ctgcaccggg agcgccaccg ggacccgggt ggaggagtca taccagatcc
     6781 tcttcgggcg cctcggcgac gagcggctgg ccgccgagca gcggccgccc gcgatcggcg
     6841 ccccacccgc cgatccgccc gcccgctggc tcgtcctgct gggctatgtc cgctgggcgg
     6901 acggccattt cagcggtgtc gagaccatgg cgcggggtgt cgcggcgcgg ttcgccgggg
     6961 tgcgcgcgga caccgtatcg gcccggtcgg gcgcgctgac cctgcggacg ggcccggaga
     7021 cccgggaggg cgaaccggcg ctcgtactgt ccggcgggga cacaccgaac ctggtcttcg
     7081 gcctgtacca gggcggtggc gcggtcagcc cgctgatgac ggtggcggcc aacggcaacc
     7141 tctcgatcga gggcagcttc ggcggccgga tgccggccgg cagcacgctg gtgacctccg
     7201 ggaccgccac cgacggcatg ctgctgccgc tgccgtccgg gatcaccccg gaacaggtgg
     7261 ccgacggccg ggtcgtgctc catgtccatc tgaccccgca tccgccgccg ttggcggaga
     7321 cggcgctgtt cagcgcggtg gagaccacgg tggacggcga caggcgggtc cggtgccggg
     7381 tgcgcgtgta caaccccgcg gtgaactgga aacagcccgt cgaacagccc ggcgcggtcg
     7441 acttcctcgt cctggcgacg gtcgcggcga cgaacggcgg tggctgacga tggctctctc
     7501 cgtggtgtac gccgtggaca ccggccatgt cgtgggcgcg ctggccctga ccggcaccga
     7561 cgccccggcc gatgtggccg cgctcgtcgg acgcgcgctg ccgctgcgcg tctccctcgg
     7621 cgagggccgc acggcgaccc ttccgctgaa cgccagggac ctcgccgtgg cggccgtgga
     7681 cgatgaaccg gccgccctcg ccgatccgtt ggccttcggg gtcgagctga cggccgaggg
     7741 caaacccaaa ccggcgctgg tgcgcctccc gtcgtggacc gaaggcatcg cgctggccac
     7801 ggacgggctg accgtcaccg tgaaggtggc cgtggcccgc accacccccg tggtcgtcct
     7861 ggtctccgac gagcaggaca cgcatgtgct caccggggag atccccgccc agcagaccca
     7921 ggtgaaactg ccggtgaccc tcgtggcgga cagcgtgcac ggtgtgctgg tgctcgtggc
     7981 gggctgggcg ggccgcctgg ggaaggagaa ggcgacatga gcgcgcccac cgcgccgacc
     8041 gccgacggga ccgacggaat cggcgggctc ggcgggctcg gcgacagcgg tgaggccggt
     8101 gagatcacgg tgcaccggtg caccgtgacg gtggtccggt gcggtgggtg gagctggggg
     8161 cccgaaccac gcggcctggt ccgccatgtg gtcgatgccc tgccggagtt gctggcggag
     8221 cacttcgccg agcggcttgc ggccgatggg ccggatatgg agatcaccga ggcgctgacc
     8281 gtcaccgtcc ggccgggccg gaccggccgt tacggctggt ccggaggggc gtccggcggc
     8341 ggaccgcccg tcgaggtcca cttcgcgccg gtggcgatgg tggaggtccc cggcgacgca
     8401 cccgccgacg gcggcgggtc gttcgaggag tccttcgcgg cggcgcctga cccgtggacc
     8461 gcgccgggcg ccgccgcgct cttcgccgaa ctcgccgagc gcggcgaact ggacgcgctg
     8521 ctcgcgctgt tgccggacgt ctcggtgcgg gcgtatctgc tcgcccttct gggcgtggac
     8581 gacacggcgg ccgcccggct gctcgccgaa ctcgtccggc ccgtcctcgc gggctcctcg
     8641 cccgccggcc cgcacggcgg tgccgcccga cccgggcccg tcgagccgct gccagagcct
     8701 ctgcccgagc ggctgcgcgc cgtggtcgcg ggcgccgacg cggccgatct gccacggctc
     8761 ctcgccgact tcctggcctc ggcggaccgt gcggaagccg tacggctggc ccggcccccg
     8821 gccgatccgc acgccccgaa caccgacgag cggcccgggg cggcgggtcg cagcgccggg
     8881 gcgagcgcgg ccgccggggc gcggaccacc ggcgaggtac aggtgtggtc cgccctgccc
     8941 ttcctgctca ccgggccact ggcacgcatc ggctacctcg acgcgatcgg gcccgccctg
     9001 gccggtgtcg aactggccga ggacgcaccg ctgttcgcgg cggccctcgc gtgcaaggtg
     9061 ctgggcgaga ccgcacgggg ctggcgccgc gcagaacgcg acggcgaggc cgcggccgcc
     9121 ttcgccggtc ttccgcctcc cctcgccgag gagcggctgg ccgacttcgc ccgccgggcg
     9181 ggccccgccc ttccggtcct cgacggcgtc ctggccctgg cggtgtgccg gggccacgac
     9241 cccgcggacc cgctgctgct cacgggggcg gacgacgggc tgctcctcat cgacgcccac
     9301 ggcatgttcc cgatcgcctg gaccccggag gccaccgcac tgctgccgta ctggcactcg
     9361 tgcggccgcc cgcccgtgct gctctgcgac gggcccctgc cgcccggcac ccttcgcgaa
     9421 ctggcctccg cgggcgtgcc gttcctcacc gccgtacggc cgctgcgcgg cgaccccgtg
     9481 gcgcggctgc cctggcgtac gcccctgtgg gccgccgagg gcgcggcacc ggacatccgc
     9541 ctcgccgcgg aactgcccgc ccacacccag cggtgtacgg ctctggtcac cgccctggtc
     9601 accgagcgcc gtgcggtgcc gctcgcacgg gacggcgctc tggagcgcac cgtcaccctc
     9661 gccgccgcgc tcggcctggc cacgatcgcc tggacgctct ggcgcgaccg cgagaccccg
     9721 gatccgctgt cggccctggc ccgcttcgcc gacctggcgg ccacggtgcg gtacgagcgc
     9781 gcggccgtcc gggtgcgcgt cccgatggga cggcgccacg cagacctcca gcgcggcggc
     9841 ctgctcgccg acgtgcccga cgtggcctgg ctgggcggcc ggaccctgac cttctcggcc
     9901 gggtgagcca tatgggcgaa cccgcggtgg agcatctgcg gatccggctg gcgggcctgc
     9961 accgcgcgct cagggccgcc gtcgagcggc aggcccgact cgccgcccga ctcaccagac
    10021 cggacctcac cccgtactgc gtgaccgacg aacaggtcga tgtgctgctc ggcgaggtgc
    10081 acgccttcac cgacacgatg gccgagccgt acgcccccgg gcagccggag ccggaagccg
    10141 aacgcgatct gaggcggcgc gcgtccgccg ggggcacggc cctgccgctg gacgcgctcg
    10201 ccgcccggtt cggcctgacc cgcgccgagc aggacgccct gctcctggcc gccgcgcccg
    10261 aactcgaccg cggctatgag cggatctacg cctacatcgt ggacaacctg aaccggcggc
    10321 tgccgagcgt ggaactgctg atcgccgtgg gcgcgaacag cgccgcggcc cgcctcgccc
    10381 tgcgccgctc cctcggcccg gccgccccgc tgcgccggta cgggctgctg cgagaacacg
    10441 gcgaggccgc ggtcgaactc gcccaggagc tcatccccgc ccccggggtg ctggacttcc
    10501 tgctgggctg gggcggcgac gtcggactgc tcggccacga ccccggcgag gtcgccccgc
    10561 ccgagccgcg cgtgctgtcc ccctatctct cctccgctcc gctcacccga ctgggccgcg
    10621 cgctgggcgc gggcgacctc gacctggccg ggctgtgggg ctgcccgccc gacggccagc
    10681 tcgacgccgt acaggcgctg gcccggtccg ccggagcgcc gctgcgcacc ctcaccgccg
    10741 accccgaggc cgatctgcgg acggccgccg tactgggcgc cgtgctgtgg atccccaccg
    10801 acgatctgca cggcgagccg cagcggccca ccgccgacgc ggtgtccgcc gcgctgttgc
    10861 gctcgcgcgt accggtgtgc ctgaccggcc tgaagccgtg gcgcccggcg gggctgctcg
    10921 ccgcccgcgc ctacgccgaa ctcaccgtgc ccgtaccggg gttcaccgac cgccgggcca
    10981 tgtggtcggc cgcgctcccg gacctgaacg gaaccctcct cgaagacctc gccgtccgct
    11041 accggatgag cggcggcgaa ctgcgcgccg tcgcagcggt cgcggacgcc ggggcacgcc
    11101 tggccggcaa cgggcacccg gagccggtcg ccgcccatgt cgagcccgcc atcgccaccg
    11161 tcacccgcgg ccgcggcggc ggcgccgtcc actcgatcac accccggcgc accgtggcgg
    11221 acctggtcct gcccgatgtc cagttccgcc agatcctgga gatcgcgtcg gccttccgcg
    11281 cctggccccg gatcgccgag agctggggct tcgcccgccg gtccgggcac ggcggggtca
    11341 aggcgctctt caccggggag cccggcaccg gcaagaccat gtccgccgag atcgtcaccg
    11401 gcatgctcgg cctggaactg ctcaaggtgg acctcgccca ggtcgtctcc aaatgggtgg
    11461 gcgagacgga gaagaacatg gagaccgcgt tccggcaggc cgaggagagc cacgccgtac
    11521 tgctcttcga cgaggcggac gccctcttcg gcaagcgcgg cgaggtcaag cacggcaccg
    11581 accgctacgc caacctggag gtcggctacc tgctgcaacg cctggaggcc agcgacggcc
    11641 tggtcatcct gaccagcaat ctgaaggaca acatcgaccc ggccttcacc cggcgcttcc
    11701 acttcgtcgt ccacttcccc cgcccggccg ccgccgaacg ccgccggctg tggcgcctcg
    11761 cctttcccga ggaggccccc ctcgcccccg atgtggacgt ggacgccctg gcccgcctgg
    11821 acatgacggg cgccgccatc gccgcggcgg cccgcaccgc ggcactggcg gcggcggacg
    11881 ggggcggcga tacgattgcc atgcgccatg tcgtacgggg tgtggcacgc cagttccagc
    11941 gcgaggcccg cctgctccgc ccggccgaac tgggcccgca cgcccatctg ctcgacaacg
    12001 catcccaggg gtgaagccga tgctgcccac cgaaccgccg ctctccctcc accgcctgct
    12061 ggccccggtc ccaccggccc gcccgcagga aacggcggtg gccacccacc aggtccccgc
    12121 cgcggccccg gcgccgcccg cggcgcagcc gccgaccgca gtcgaacgtc tgctcgccgg
    12181 ccaggaccag ctgggcaacg cggcggtggc gggcgctgcg gcccgtacga gccctgtcgt
    12241 gccccaaccg gcgggcgcgg tggtggtgct gaagccgaag gccgctcagc ccccagcgtc
    12301 cccctgaccc tcggcgaggc gctcggcgac ctgccgctgc aactcctcta cgcgctccag
    12361 agacgcgtac gcccggtcca cctcgtcgtc gtccaccgaa ccggcgcccc agttcgacgg
    12421 ggagcgcagt tccttctcca accggcggac ggacgcggtg tgctcggtgt gcaggacctc
    12481 cagcagggag ccgccacagg ccagggcgtc ctcggcggcg gaggattcga agaggcggaa
    12541 gaccgtcgaa cggcccgcgc gcagctcgcc gagccggtag cagacgatcc ggtcctcccg
    12601 gccgggatcg gcggcgggaa tgcggacgag cggcatcagg tcgaggtccc cggccaggag
    12661 ccgcagttcg gtgtcgatca ggccgtcggg ctcggccgcc gggccgcccc ggtcgggcgg
    12721 tacggccagc tgccagggct ggttggtgaa gagcgccagc agacgcagcc gccacagccc
    12781 cccttccgcg atgatgaaga cctcttgcgg gaacgcgacg ccatagcatt ggtgcagcac
    12841 ctcgtgcggg ccgagcccca tcccgtacag cgctcgcgcc agccgggcca tcgaggcgta
    12901 gtcgtcgcgt gcggcttcgg cgcgcagtcg gtcgacggcg tccgaggtca tcgccggcct
    12961 cctcggcggc ctctgccttc ggacggcttc ttcgtggcgg cgtccaaggc caggctgatg
    13021 ttcttccaga gcttggcgag ctgggaagcg gtcatcgccg agatgatctc ctgggtcgtc
    13081 tcatgcgcct tgtcgacggc ccgctggaac tcggggtcct ctcccaccgc ttgaagcctg
    13141 ttcagggcct cgacatcggc gtcgagccgc tccttgagcg ctctgacggc cgggtttccg
    13201 ccggtcaggc tcgggttgtc ggccatcagc atggcggtgt cctcgacata ggagaagatc
    13261 ttgttctgaa gaaggcgctg ggccgtctcg tccagtcctg gggtggcgcg ggtgaactcc
    13321 ctggccaggg tacgggcgct ggcgttcgac tgcgactgga tgatgagcgc gtacatccgg
    13381 tgcgcggtgc gcagcgtctc ctcgccgccg cgcacgcgca tcttgccctg ggcggcccgg
    13441 cggacggcca gcggagtgac ggtgaggccc cgggcctcgt cgccggggag cgggctcgtg
    13501 ccggtgctgg cgtcgggtgc gtacgccacg gagaagtcgg tgccgaatgc cttcatgagc
    13561 gcgttgcgca tcgcccggcc ctcggcgccg cgtgcaccga agagcaggcc ctggacctcc
    13621 agcagggcga ggccccgggc gtcctggaag atcccgctga cgcggccctc ctgatggtcc
    13681 cacgccttga tgagcaggtt cggctccgtc gggtagagca tctgcggata cttcttggcg
    13741 atgccgaccc gaatggcccg gtccagctcg ttggccagcc gcgtcagctg tttcgcgcgg
    13801 cggtcggcct tcctgcccca gtcgaagtcg tcgaagtggt agccgccgat cgtgagcagc
    13861 ggatgaaccc ccatctcggt gagcaccttc tcatacgctc tgaggacacc cacgccgctg
    13921 atggcggcga cgccggtgtc ggcgtcctgg ctcacgatgt ggacctgctg gttcacgtcc
    13981 ttgaggatgt tcaccgccga cttggtgtac tccgagcgga tcacctcgtc gcggaagatg
    14041 ccgtagggaa gcgcgccctt gtcgcgcaga cctttctcgt tggcctcggc ccgccgcttg
    14101 ttggaggctt cgagctgctg gtaggccgcg cgtacctcct cgatgccgac cttgcgattg
    14161 cgcttgccct tgacccatct gggggtccag acgaagccga acaccgccat caggagctcg
    14221 ggcttgcggc cgacgctgtt gatggcgccc ccgatggcgt cgccctcctg cggattgagc
    14281 cgctcgaagg agttgatgcc gatgacaacg gcggttcgcg ccgccgccat gtcctgggcg
    14341 tgcagggccc ccgtgccctg ccacgccttg tccaggtagc gggtcgcgac cgtggggttc
    14401 ttcgtgatct cgccggggat ggcggccatg ttgacgacga agccgatcca gcggtcgttc
    14461 ccctcgatgg gctggtcgat cggctggagc tgcacgaccg cgtgcgggtg gcgcttgatg
    14521 gggaacttcc cctgggcccg gtcgatccgg tacgggaaga gctccttgta cgaggtgctc
    14581 ttggaggggt tgatggccac catcacggcg taggtgtcgg accccttctt cttcagctcg
    14641 atccgggtca ggcggtggcg tctcttgatg gccgggagcc cttcccgaat cgactcctcc
    14701 gtggctgctt ccgcgttgag caggcgcgtc gcctcacgta aggccgcgtc cagggcgcgc
    14761 tggatgtcct tccaggaccg cttgtccggg cgcttcttct tcgggccgcc gctgcgtttg
    14821 ggcccgcgcc ggtcggggcg tcgccgctgg tccggacgcc gccgtcggcg cgggccgccc
    14881 ggccgcctcc ggtccgggcg gcgcttcggc ttcggtttcg tcttgtcgga cttcggcttg
    14941 atcctggacc atagcttctt caccaggccc acgatcttgt cgatcaccca gtccaccgcc
    15001 cggttcaccg gtttggccat cgcctggacg atgcccttga cccgggaggc gatgccgccg
    15061 actcccagga tcgcggcgag gacgccgagc aggacgggga tggagcgggc cagggcctgt
    15121 tcgatcaggc ccggaacgcc gccgctgccg cctcccgcga tcgcgatgac cgcgtcgagc
    15181 acggcgttca cgaactcgac gatctggcgg gcccgagtga cgatgaagcg cacgatgtcg
    15241 atgatcagct tcaccgcgcg gacgaacgcc gacgcggggt tgagcagcga gatcacccac
    15301 atgatcccgg cgacgacgat cgtcggcgtg acgtaggcga tgaccttgtc cagcaggtcc
    15361 ttgcgcaggt cgcccacgcg cgtcttgagg tcgtcccaca tccccgcgac gccccgtttg
    15421 cggacctccg cgaccagcgg caccgccgtc tcggccgccg agaccgccgg ttccatcttc
    15481 ggtaccttgc ggacgatccg ggcgcggatc gactgccagg tcagcccgag cagagaggcg
    15541 agcatccgca gaacgccctg ggtgtcgaac ctcgacggca gtgcgacgcc cgcctcggcc
    15601 gtcttgccca gcagccagga caggatgccc tgctggaggt ggcggccgat gttccgcagg
    15661 aactgccgca gaccggcgcc gacggccgag accaggttgc gcaggaagcc gatcgggtcc
    15721 ttgaggatca gcatgaccgc cgacgcggcc ttggcgagaa ccgacagcag cagccgcttc
    15781 agctccagga tggtgttgat cacggccttg accgcgtcca cggccttggc caccaggccc
    15841 ttgttcttct ccttctccgc cgcgatctcg tcgtccacgg acctcagcgc gtcggtgtac
    15901 ttggtggcca gcgtgtcgac gagctgagtg cccttgtcgt ccacggactg cgtgagttca
    15961 tcgaacctgt cggtgaactc ggcggccgcc tgctgcccga tggaccgcag atcggccggg
    16021 agcccgcgca ccgcctcccg caactcggtc cggccctggg cgatacggcg cttggcccgg
    16081 ttcagctccg cgccgatggt gtcggcgacg tccgagatca cctgacgcat ccgccggacg
    16141 tagctgtcgc gggcctcctc gaagatcttg tccgcttcgg cgggcagccc ggcgaacttg
    16201 tcccgcaccc agcgcagttt gcccgtcaca cccgagtacc ggcggtcctt gtactcgtcc
    16261 atcttccgct ggtgctcggc ggtgaacgcg tcccgcgccg ccttctcacc cctgccgaac
    16321 tgatcgtcga ccagcttgtc gaggccgtcg agaatggcct cgacgtcctt cttcatcgtg
    16381 tcgaacaccc cttgcaggag cgtcgtcacc tgggcccgct tgtcctcgtc ccggcccttg
    16441 gcgccggtct tgcccgcacc gacccgctgc ccggtccgca cccgctgggc gcccatcgcc
    16501 cccatggacg ccgcgccgag ccgtcgcgcc cgcgcggtgg ccgcgttcag ctccttcttc
    16561 tcatgtccgc gcatccggcc gggggccacc gcggagtggc gctcggcggc cttcttctcg
    16621 ttcagcgcgc tcttgaaggc gggctcgttg gacttcttca gctggccctc ggtgacctgc
    16681 gcgtccgtca tccgccggtt gagcttgtcg gggcccgcgg acagatcggt ggcggacggc
    16741 ggcagcttgt ccggtacggc gttcgccggg tcgggcgtgc ccggcgtccc agggggccgg
    16801 tccggggcca gcggcaccac cttcttgggg acggccgccg aggtgtccgg cggggcggcg
    16861 gtcgtggtgg cgatctgctg ggcggagtcc gacgtgccct cgccgacctt gccgtgcact
    16921 tccgcgcgta cctcatcggc cttgccggag tcggcgaact tgtccgcctc gtccaggttc
    16981 ttcggtgcct tctcggcgat cgccttctcg accgccctga tgaacgcgtc cttgtcgaag
    17041 tccttcggct tggcctcgtt catcttctcg gcgttggcgg tcttgccctg cgcctcctcg
    17101 tcgtccttgg gcggccgggc ggcgtcctgc gcggccccgg cctccgccct cgggggcgga
    17161 tgcgagctcg cgaccgctcg cttcttgctc cgtacgtcct tcttcagcgt cgtgaatttc
    17221 ggatccgcgt ccgggccggg ccgggccttg gcctccggcg cggcatccgg ggcgggccgg
    17281 gactcggcat ccggagtggc gtccggggcg ggccgggact cggcctctgg cgtggcgttc
    17341 ggggcggcct ccggggcggt ggccgcgggc cccgtctctg ccctgtccac cggtgccggc
    17401 tcgggttcgg ccgtaggcgg tcgccggggg ccgggctcgg tgcggcgggc cgccgcgacc
    17461 gcgccgttgc cgaccgtgtc ctgcccggca ggcggcggcc gggtgggcga aggcggtagc
    17521 acggcaggtc cgcgcccgcc ggacagggcg gccgtcaccg ccgcgttgga cggagggaac
    17581 tggtgccgtg cgaggtcgcg cggctctggc tgatcttgtg tgccgcgtac ctctggccga
    17641 ttctgtgtgg gggcgggtac tgtcttcgac accctgggcc gcagcgcgag agccttcggc
    17701 ggtggcatcg gacggaaccc ctcccacgca tgtcggtgcc gacaggaacg tggcgtcccg
    17761 ctgacacttc ccgacgaagg gtggcaccac gggcgtgacg aggccgtcac ccccgtgttt
    17821 cccctacgtc tccatggagt tggggagccc gcggcccgtg ccggagcggc ctcgtgccag
    17881 acatgatggc caacatgtgt ggttggagag gacgcaccgg gggaagaggg gatgaagagt
    17941 ggtgaggccg cgacgctcgg acgtcgcgcc cggcgcggtg ggttcacccg cgcggatgag
    18001 gtcaacggct ttcgcccttg tctaaggaaa ttcgcagagg ttgcccatgg gggccttttg
    18061 gcgcgcttta gggtcgacgg cgaagctagc atcgacatcg agccagccgg tgtagccgcc
    18121 gacgacctcg atgcatgggt taaaaaatcg atggaggagt cttggtcgac gccccgcacc
    18181 ccgctgtgtc actgcccacc aagcggagct gccccttcga tcctcccgat ggctacaccc
    18241 ccctgcgcga gcaggagagg attacccgca tgagttatcc gggcggcacg cccgggtggc
    18301 tcatcacccg tcacgccgaa gccaaggaac tgctcactca taagagcttc agcgcccgcc
    18361 aggaagggat aatctctccc gtccccacgg agctggcgta cgatggcccg gccgatccgg
    18421 gcgcctttgc gaagacggac gacccggtcc atagtaagta tcgcaagctc atcacaggct
    18481 ttttcacggt ccgtcgcaca cgtcagctcg cccccatgat cgagcgaatc gtgcatgaac
    18541 aactcgacga cctggaaaag gccgggccgg gtgccgatct ggtcgatgtc ttcaccgaat
    18601 ccgttccctc ccgggtgatg tgcgagatga tcggcgtccc cgaatccgag cggaagagcc
    18661 tccagcggca tgtggagacc ctcggacggc tctcctccac cgtccccgag gcgctggccg
    18721 ccgtgtccgg aatgagtgga ttcctggccc gcttcgtgcc gaccaggatg gacgaccccc
    18781 gggacgacat cctcggggac ctcatccgtg gcgggcagct caccgagcaa gaactcatgg
    18841 gcatgaccgc cacgctgatc accggggcca tggacaccac gggcaacatg ctcgccatgg
    18901 gcatcttcac cctgctcgag caccccgacc agctggccaa gctccgtgag gacccggagc
    18961 tcatgggggc cgcggtcgag gagctcctcc gcttcctcac catctcccac ctcggggcca
    19021 gccggtgggc gctcgaagat gtcgagttcg ccggacagac catcaagaag ggcgaggtgg
    19081 tcaccgtcgc cctccccgcc gtcaaccgcg accccgagcg ctacgacaac cccgaccagc
    19141 tcgacatcgg ccgtacggac catgggcacc tggcgctcgg ccacggtgtt caccagtgtc
    19201 tcggccagca cctcgcccgc acgatcctgc gcgtcggcta cgaggccctc ttcgaccggt
    19261 tccccacgct ccaactggcc gtgccgtccg aagagatcca gatgcgcgac gacttcgtgc
    19321 actacggccc caggtcgctt cccgtcacct gggacgactg atcgagacgc cgaacggcgc
    19381 cgaatgtggc ggacggtgtg gagttctcgc accgtccgtc acgcgagagg gcccgcggaa
    19441 cgtcgaggtg ccggcccgag tcacccccgg atccctgggc cggtcaactc cgttgacggc
    19501 ccgctcatcc cgaatgacaa ggtaggactg agacccgatg aggatcaccg ccgaccgtga
    19561 ggcgtgttgt gcggcgggtc agtgcgcgct catcgcgcct gacctgttcg accagagcga
    19621 cgatgacggc accgtcgttc tgctcgacgc acgacccgac gccggacggc tggacgccct
    19681 gcgcgaagtc gtatcccgtt gccccaccgg tgcgatccgc atcgaagaag accctggcgc
    19741 gtgaaaacgg cgtcaaaaac ggagcgcgaa tagcggcgga gaacccacag tggcaaacgc
    19801 cacacgcgcc ggtgaatcgc tggtgaaacc gaatcccggg aacgctgccg ggagcgtcga
    19861 ccgagcctgc gtgggtttct agggtttccc ttacgggtct agggctagtg tggccggtgt
    19921 ccgtctggca atgcgtgttt cataactttt agggccgttg agctctccca gcgaacgacg
    19981 cgttaagtgt ggagtttctg atgcctgctg catccaacca gaacaaagcc gttgaagcac
    20041 tgcgcaagtc gttcaaggaa atcgagcggc tcaggcgtca gaaccgccag ttgatcagtt
    20101 cggcgaccga gcccattgcc atcatcggta tggcctgccg atttccgggt ggagtgaatt
    20161 ccccggaggc cctgtggcag ctggtcgccg acggagcgga cggcatctcg cccttcccca
    20221 caaaccgcgg ctgggacgtg gaagggatct acaatccgga cccggaccat ccgggtacca
    20281 gttacgtacg cgaaggcgga ttcctccacg acgccgacca attcgactcc gcgtttttcg
    20341 gcatctcgcc ccgtgaggcc cttgccatgg acccccagca gcggctgctg ctggagacct
    20401 cgtgggaggt gctggagcgg gcgggcatcg accccgcgtc cctgcgcggc agccagacgg
    20461 gcgtcttcac cggcgccatg cacaccacct acgcgtccga ggccgcacag atcccggacg
    20521 agatcgagcc ctacctccac aacggcgcca ccaccagcat cgcctccggc cgggtctcct
    20581 acaccttcgg cttcgaaggc cccgcgctga ccgtggacac cgcctgctca tcggcgctgg
    20641 tcgccctgca cctggccaca caggcgctgc gtcagggcga gtgctccatg gcgctggtcg
    20701 gcggtgcgac cgtcatggtg agccccaagg gcttcgtcac cttcagccga cagcgcggac
    20761 tggccgtcga cggccggtgc aaggcgttcg cggactcggc ggacggcacc acatggtccg
    20821 agggcatcgg tgtgctgctg gtggagcggc tgtccgacgc gcggcgcaac ggtcaccaga
    20881 tcctcgcggt ggtgcgcggc tccgccgtga accaggatgg cgcgagcaac ggactgacgg
    20941 cccccaacgg cccgtcacag cgccgcgtga tccggcaggc cctcgagaac tgcgagctga
    21001 ccaccagcca gatcgacgcg gtcgaggcgc acggtacggg tacgacgctg ggcgacccga
    21061 tcgaggcaca ggcgctgctg gccacgtacg ggcaggaccg gccggaggga cggccgctgt
    21121 ggctgggctc gctgaagtcg aacctcggcc acacacaggc cgccgccggt gtggccggtg
    21181 tcatcaagat ggtgatggcg atgcggcacg gcgtactgcc gaagacgctg cacgtcgacg
    21241 ccccgtcgag ccacgtggac tggtccgagg gccaggtcga gctgctggcc gaggcgaggc
    21301 cgtggccgga gacgggtgag ccgcgcaggg ccggtgtgtc ctcgttcggt gtgagcggca
    21361 cgaacgcgca tgtgatcctg gagcaggccc cggaggtcga ggccgacacc gaggccgagg
    21421 agcccgccgg cggtggtgtc gcgggccccg tggcatgggc cgtttcgggc aagagcgacg
    21481 ccgcgctgcg ggcccaggcc gagcggctgc gggagtacgt ggcggagcgt tcggagctga
    21541 gcgccgccga tgtggctctg tcgctggcga cgaccagggc cgcgttcgag cagcgcgccg
    21601 tggtgatcgg gaccagccgt caggagctca tcgagcgcct ggaggcggtg gccgagggcg
    21661 ccgagctccc cggtgtggtc cacggaagtg acgccgaaac acctggtcgt tcggtgtttg
    21721 tgttcccggg gcagggggcg cagtgggtgg gtatggcggt ggggttgttg gagtcctcgc
    21781 cggtgttcgc ggaggcgatc ggcgagtgtg aggcggcgct gtcggcgtat gtggactggt
    21841 cgttgacggg tgtgttgcgt ggtgttgagg gtgcgcctgg ttttgatcgg gtggatgtgg
    21901 tgcagccggt gttgtttgcg gtgatggtgt cgttggcgcg gttgtggcgt tcggtgggtg
    21961 tggagccgga tgcggtgatg ggtcatagtc agggtgagat tgctgcggcg tgtgtggcgg
    22021 gtgggttgtc gctggaggat gccgcgaagg tggtggcgtt gcggtcgcag gcgatcgcgg
    22081 tggggcttgc tggtcgtggt ggcatggtgt cggtcgggtt gtccgcggag caggcggagg
    22141 agcgtatcgc ccggtggggt ggggcgattt cggtggcggc ggtcaatggt ccgggttcgg
    22201 tcgtggtggc cggtgacccg gacgcgctgg atgagatggt tgcggagctg gagggtgagg
    22261 aggtgcgggt ccgtcgggtt ccggtggact atgcctcgca ttccgcgcat gtggagggga
    22321 ttcgtgagga gctgctgagg gttctggcgg accttcagcc gcggtcctcg gaggtgccgt
    22381 tctactcgac ggtgaccggt gagctggtgg acacggctca gctggacgcc gagtactggt
    22441 accggaacct gcggcagacg gttgagctgg agtccacgac tcgcacgctg ctcgacgcgg
    22501 gccacaccgt gttcatcgag gtcagcccgc atccggtgct gacccttccg gtgcagcaga
    22561 cagttgaggc cgctgagtcg cgggccgtgg tcgtggggac actacggcgc gatgagggcg
    22621 gggccgagcg gttcctgacc tccgccgctg agcttcacgt cagcggggcg cgcgttgact
    22681 ggcaaaaggt gttcgccgga cacggcgccc accgcgttga attgccgacc tacgccttcc
    22741 agcacgagcg cttctggctt gacgctcccg ccggtgtggg tgatgtgggt tcggtggggt
    22801 tgggttcgct ggggcatccg ttgctgggtg cggtggtgtc gttggcgagt ggtggcgggg
    22861 tgctgctgag tgggcggttg tcgttggcca cgcatgagtg gctggcggat cacgccgtac
    22921 acggggtgat gctgctgccg gggacggcgt tcgtcgagct ggtggtacgg gcgggcgatc
    22981 aggtcggctg cggccgggtc gaggaactgg tcatcgaagc gccgctgatc gtgcccgaga
    23041 agggtggcgt acacctccag gttgaggtgg gggaggccga cgcttccggc ttccgtgagg
    23101 tgagcgtgta ctcgcgggag gaggcggacg gcgatggcgc ggcatgggtg cggcatgccc
    23161 atggtgtgct cggttcggcc gtgcccagct ccgagacaca gtacgacttt ggtgtgtggc
    23221 ctccggtggg gctgagttgg ttgatgtgtc gggtgagtat gtgcgggctg cggagaacgg
    23281 gttggagtat gggcctgttt ttcaggggtt gaggcgtgcg tggcggcgtg atggtgaggt
    23341 gtttgctgag gttgggcttc cggaggggga gcgggagcgg gcggggcagt ttggtttgca
    23401 tccggcgttg ttcgatgcgg cgttgcatgc gttgggtgtg agtggggctc ttgcgg
//
