LOCUS       NZ_CP019458            26454 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 chromosome, complete
            genome.
ACCESSION   NZ_CP019458
VERSION     NZ_CP019458.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8656489
            Orig. end                         :: 8682943
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019458.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26454
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="39"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26454
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26454
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16454](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16454
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    436..450
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.39"
                     /tool="antismash"
     gene            1340..2092
                     /locus_tag="BV401_RS35575"
                     /old_locus_tag="BV401_35645"
     CDS             1340..2092
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="BV401_RS35575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35645"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_069872403.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 9.7e-10, bitscore:
                     37.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGKEDETTVLDLTLG
                     NFAEIGLTEVAIVVGYRKEAVYERKEALERKYGVKLTLIDNDKAEEWNNAYSLWCARDA
                     IQHSVILANGDTVHPVSVEKTLLAARGNGQKIILALDTVKQLADEEMKVVADPDKGVQK
                     ITKLMDPAEATGEYIGVTLIEGEAAADLADALKTTFERDPDLYYEDGYQELVNRGFKVD
                     VAPIGDVKWVEIDNHDDLAKGREIACLY"
     gene            2080..3153
                     /locus_tag="BV401_RS35580"
                     /old_locus_tag="BV401_35650"
     CDS             2080..3153
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056049.1"
                     /locus_tag="BV401_RS35580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35650"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_069872399.1"
                     /sec_met_domain="Fe-ADH (E-value: 6.3e-23, bitscore: 80.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPLVVDIRAGALDDLAGVLADQRISASGKLAIAISG
                     GSGAVLRERLAPALPGASWYEVGGGTLDDAIKLADRMKSGHYDAVVGLGGGKIIDCAKF
                     AAARIGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRF
                     VRSGIGDALSNVSAVADWELSHRETGEQIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLFPKRAASHGEQCGLAAAFAMRLRG
                     AHEESEHMAEVLHRHGLPVLPEEIGFTVDEFVQVVEFAPKTRPGRYTILEHLDLSTDAI
                     RDAYADYAKAVSQTISG"
     gene            3119..3910
                     /locus_tag="BV401_RS35585"
                     /old_locus_tag="BV401_35655"
     CDS             3119..3910
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="BV401_RS35585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35655"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_079259576.1"
                     /transl_table=11
                     /translation="MPKQSVKPSVAELRPVVHPEGVKDRRSGEHWAGRLYMREISLRCD
                     RYLVNTRVTPNQLTYLMTVFGVLAAPALLVPGIAGAVLGVLMVQLYLLLDCVDGEIARW
                     KKQFSLGGVYLDRVGAYLCDAAVLVGFGLRAADLWGSGRIDWLWAFLGTLAALGAILIK
                     AETDLVGVARHQGGLPPVKEAASEPRSSGVALARRAAAALKFHRLVLGIEASLLILVLA
                     VVDQVRGDLFFTRLGVAVLAGIALLQTLLHLVSILASSRLK"
     gene            3922..4794
                     /locus_tag="BV401_RS35590"
                     /old_locus_tag="BV401_35660"
     CDS             3922..4794
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="BV401_RS35590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35660"
                     /product="glycosyltransferase"
                     /protein_id="WP_069872392.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.1e-09,
                     bitscore: 35.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVVLTMGNRPEELRALLDSVAKQDGDPVEAVVVGNGSPLPP
                     LPEGVRTVELPENVGIPAGRNVGIEAFGPGGSDVDVLLFLDDDGLLPGTDTAELCRAAF
                     AADPGLGIISFRIADPDTGVTQRRHVPRLRASDPLRSSRVTTFLGGANAVRTAVFQQVG
                     GLPDDFFYAHEETDLAWRALDAGWMIDYRSDMVLHHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPALLVPVYLGVWLLLTLARRPSKTALRAWFGGFREGWKTPCGPRRPMKWRTVWRL
                     TRLGRPPVI"
     misc_feature    4862..4880
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            4874..5809
                     /locus_tag="BV401_RS35595"
                     /old_locus_tag="BV401_35665"
     CDS             4874..5809
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972239.1"
                     /locus_tag="BV401_RS35595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35665"
                     /product="ABC transporter permease"
                     /protein_id="WP_079153686.1"
                     /transl_table=11
                     /translation="MSETTHDGAVAVSGPPSADDGLSPAELAQKYGLSVSGARVGLREY
                     INQMWGRRHFIVAFSSAKLTAQYSQAKLGQVWQVATPLLNAAVYFFIFGLLLKSSRGMP
                     NDMYIPFLVTGVFVFTFTQASAMAGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLVVVLLGFGHYPAFSWLLILPTLALQFVFNTGLSLIMARLGAKTPDLAQLLPFI
                     LRTWMYASGVMFPLARTLEHAGASKWISDAMLGNPAAVYMDLMRYALIDDYTAANLPPH
                     VWALALGWAVLFGAGGFVYFWKAEEQYGRG"
     gene            5802..6653
                     /locus_tag="BV401_RS35600"
                     /old_locus_tag="BV401_35670"
     CDS             5802..6653
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056053.1"
                     /locus_tag="BV401_RS35600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35670"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_069872388.1"
                     /transl_table=11
                     /translation="MAEQTLDKGAKAAQAEQAGKAEQAAQAASARSRVPTVVADDVHIV
                     YRVNGGPKGKGSATAALSRILRRKGAPGMREVHAVRGVTFVAYKGESIGLIGSNGSGKS
                     TLLKAVAGLLPTERGKVYTDGQPSLLGVNAALMNDLTGERNVILGGLAMGMSREQIRDR
                     YQDIVDFSGINEKGDFITLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQ
                     KRSEARIRELRQEAGTVFLVSHNNKSIRDTCDRVLWLEKGELLMDGPTDEVIKAYEKET
                     GK"
     gene            <6858..7622
                     /locus_tag="BV401_RS35605"
                     /old_locus_tag="BV401_35675"
                     /pseudo=""
     CDS             <6858..7622
                     /NRPS_PKS="Domain: PKS_KR (1-107). E-value: 3.4e-07. Score:
                     22.3. Matches aSDomain:
                     nrpspksdomains_BV401_RS35605_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="BV401_RS35605"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35675"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TDEESMATAVAKAEAEHGAVGALVNSAGYAMSGCIEEASMAEVRE
                     QFETNVYGLVRLSQLVLPGMRAHGGGTIVNIPSVFGRYAVPGSGFYNATKHAVEALSDS
                     LRNEVADFGVRVVLVEPGPVRTTRFGATYVANLRPVSRTYETFRRESAEYFEAIYTGSR
                     RTLAGSFAIQPDDVARRVARVVAKGVRGGRARARYPVGQLPPTRRAIKERPRMAYLPFG
                     SGPVTARERGTAALRPSRRTAPAESAACPHRP"
     aSDomain        6864..7181
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS35605_PKS_KR.1"
                     /evalue="3.40E-07"
                     /label="BV401_RS35605_PKS_KR.1"
                     /locus_tag="BV401_RS35605"
                     /protein_end="107"
                     /protein_start="1"
                     /score="22.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="DEESMATAVAKAEAEHGAVGALVNSAGYAMSGCIEEASMAEVREQ
                     FETNVYGLVRLSQLVLPGMRAHGGGTIVNIPSVFGRYAVPGSGFYNATKHAVEALSDSL
                     RN"
     misc_feature    7686..7703
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.78"
                     /tool="antismash"
     misc_feature    complement(7688..7703)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.89"
                     /tool="antismash"
     misc_feature    7762..7778
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    8592..8607
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.74"
                     /tool="antismash"
     gene            8820..9560
                     /locus_tag="BV401_RS35610"
                     /old_locus_tag="BV401_35680"
     CDS             8820..9560
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056063.1"
                     /locus_tag="BV401_RS35610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35680"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_069872380.1"
                     /transl_table=11
                     /translation="MSPGEAHVAPYSRRERLRIATIREIKDVARTLLVQEGPENVTIRA
                     IAREMGMTAPAVYRYFSSRDALILQLRVDIFEEMARFMRGVLGQHPEEEPGRRWISGAR
                     ALRVWAIKHPHEFGLILGPWAPGLGREETKPERHMSWVFGSVFSDLVADLWRVRGFPAP
                     EVEELDPGLARTLTVLSEDQDVDMPPGAIAVMLRCWVRLYGVISMEALGHMSFALSEGQ
                     HFFEFELRDLCRVLDISEFYEEVV"
     gene            10001..10864
                     /gene="hpnC"
                     /locus_tag="BV401_RS35615"
                     /old_locus_tag="BV401_35685"
     CDS             10001..10864
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088373.1"
                     /locus_tag="BV401_RS35615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35685"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_069872377.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.7e-40,
                     bitscore: 136.3, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 6.6e-39, bitscore:
                     132.7, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDKAAHENFPVAPFFLPRAWRTDLMAVYGYARLVDDIGDGDLAP
                     GGADAELLGLDRDRADDALAMLDAFEADLHRVFRPAGEPRHPLLRALRPTVHRHGLTPE
                     PFLGLIEANRQDQSVRRYATYQDLLGYCELSANPVGRLVLGITGTTSPERIRHSDAICT
                     ALQIIEHVQDVAEDLRRDRIYLPAEDMKRFGVTEADLAAPRGGVRLRALVAKEAERAAA
                     LLNEGTPLVGSVHGRLKVLLAGFVAGGRAALRAVAAAGHDVLPGPPRPTKLSLLREVGA
                     TLRREG"
     gene            10873..11823
                     /gene="hpnD"
                     /locus_tag="BV401_RS35620"
                     /old_locus_tag="BV401_35690"
     CDS             10873..11823
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056065.1"
                     /locus_tag="BV401_RS35620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35690"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_069872613.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.1e-57, bitscore:
                     193.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.5e-68,
                     bitscore: 229.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGSPHASAPVLAAYRYCEAVTGHQARNFAYGIRLLPTEKRHAMS
                     ALYAFSRRVDDIGDGPLDPEEKRTRLADTRALLDRMRSGGIEEDDTDPVAVAVSHAAHR
                     FPIPLDALDELIDGVLMDVAGQTYETWDDLKVYCRCVAGAIGRLSLGVFGTAPGTGHSE
                     DELERAPYYADTLGLALQLTNILRDVREDAATGRTYLPADDLAKFGCATAFRSSTAPPD
                     ADFTGLVHFEVRRARALFAEGFRLLPLLDRRSGACVSAMAGIYRRLLDRIAKDPAAVLR
                     GRVSLPGHEKAYVAVRGLAGLDARAVERRGTGRAV"
     gene            11820..13304
                     /gene="hpnE"
                     /locus_tag="BV401_RS35625"
                     /old_locus_tag="BV401_35695"
     CDS             11820..13304
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056066.1"
                     /locus_tag="BV401_RS35625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35695"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_231981215.1"
                     /transl_table=11
                     /translation="MTHSALDPAPPAGPRPRGRAALVIGGGLAGTAAALALADAGLRVT
                     LIEGRPRLGGLAFSFHRSSPAGVLSVDNGQHVYLRCCDAYQWFLERVGAARLAPLQGRL
                     DVPVLDARGRSGRRLGRLRRTALPVPLHLSASLATYPHLSLAERAQVGRAALALGRLDP
                     RDPELDGVDFAGWLRRHGQSPRAVEALWDLVGVATLNATASNASLGLAAMVFKTGLLSR
                     PGAADIGWARAPLGELHHTHARRALDAAGVTTELRTRVTGVTRTPEGRWSAATAGRPAD
                     GSPVEADVLVLAVPQREAHALLPDGALKDPGRLLRIGSAPILNLHVIYDRTVLRRPFFA
                     AIGSPVQWVFDRTDASGLRDAPGAGDSQYLAVSQSAAYDDIDRPVAELRARYLPELERL
                     LPVARGARVRDFFVTRERTATFAPVPGVGLLRPSAPTDAPGLYLAGAWTATGWPATMEG
                     AVRSGLSAARTALTDLGRPHVNPLPALGGGTPKEVA"
     gene            13301..14398
                     /locus_tag="BV401_RS35630"
                     /old_locus_tag="BV401_35700"
     CDS             13301..14398
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713873.1"
                     /locus_tag="BV401_RS35630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35700"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_069872375.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.7e-58, bitscore:
                     194.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTTKNRGETVTSATPAADTAGVMPLLERGRTLATPVLRAAVHR
                     LAPPMNTVAAYHFGWIDAEGNPAEGDGGKAVRPALALLSAEAAGAAPEAGVPGAVAVEL
                     VHNFSLLHDDLMDGDEQRRHRNTVWKEHGPAQAILVGDALFALANEILLEIGTVEAGRA
                     TRRLTAATRKLIDGQAQDISFEHRERVTVEECLEMEGNKTGALLACAASIGAVLGGADD
                     RTADILERYGHHLGLAFQAVDDLLGIWGNPEATGKRTWSDLRQRKKSLPVVAALAAGGP
                     DSERLAQILAADARKPEEEFADFSEEEFAVRAALIEQAGGRDWTSQEARRQHATAMEAL
                     GSVDMPAEIRARFVALADFVVVRKR"
     gene            14508..16454
                     /gene="shc"
                     /locus_tag="BV401_RS35635"
                     /old_locus_tag="BV401_35705"
     CDS             14508..16454
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175184.1"
                     /locus_tag="BV401_RS35635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35705"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_069872373.1"
                     /sec_met_domain="T2TS (E-value: 7.7e-153, bitscore: 508.8,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATPTVQPSESSESKTLSVAREATARAVEHLLSRQDERGWWKGD
                     LETNVTMDAEDLMLRQFLGIQDPDTLDAAARYLRSQQAPDGTWATFHGGPPELSTTIEA
                     YVALRLAGDEPDAPHMTAASAWVRSRGGVAASRVFTRIWLALFGWWRWEDLPELPPEII
                     YFPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPRKPNPPLPQAPI
                     ATWDGVFQRLDRALHAYHKVALRPLRRSALRSCARWIVERQENDGCWGGIQPPAVYSVI
                     ALHLLGYDLDHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGLAP
                     DHPALVKAADWMMAEQIDRPGDWSVRRPGLPSGGWAFEFHNDNYPDIDDTAEVILALRR
                     VDHPEPARIEAAVRRAMRWTLGMQSKNGAWGAFDVDNTSPLPNKLPFCDFGEVVDPPSA
                     DVTAHVVEMLAHEGRTYDARTRRGISWLLSEQEPSGAWFGRWGTNYVYGTGSVVPALIS
                     AGVPASHPAVRRAVRWLESVQNEDGGWGEDQRSYLDAEWMGRGASTASQTAWALLALLA
                     AGERGGAAVERGVTWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRF
                     VHGEPTGARPRSS"
     gene            16454..17170
                     /locus_tag="BV401_RS35640"
                     /old_locus_tag="BV401_35710"
     CDS             16454..17170
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056069.1"
                     /locus_tag="BV401_RS35640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35710"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_079259577.1"
                     /transl_table=11
                     /translation="MSADPAPEAGGAPLLIACALGIEWFALRGAGPGAAGEVTVLRTGM
                     GPQSAERAVTRALTAGSGEWRTAVIATGFCAGLAPGMHPGDLVVADETRDPAGRTVCTG
                     TRILADALSRPLPGGPRRAVHIGPVVGSDHVVRGAERTALHRTGAIAVDMESAATLRTA
                     VGHGVRPVAAVRVVVDAPEHELVRIGTLRGGISAFRVLRTVLPAFFHWHRSSLLPGGEL
                     DGHASPPDHPGRDVSL"
     gene            17121..18146
                     /gene="hpnH"
                     /locus_tag="BV401_RS35645"
                     /old_locus_tag="BV401_35715"
     CDS             17121..18146
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384766.1"
                     /locus_tag="BV401_RS35645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35715"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_069872368.1"
                     /sec_met_domain="PF04055 (E-value: 9.6e-17, bitscore: 60.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.7e-08, bitscore: 32.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIRVATYLFEQKMIKRRDKFPLIVELEPLFACNLKCEG
                     CGKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIARQLVERKKYV
                     FLCTNAMLLRKKMHLFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRG
                     FRVTTNSTFFNTDTPQTIVDVLDFLNDELEVDEMMISPAYAYEKAPDQEHFLGVEQTRE
                     LFRKAFAGGNRRRWRLNHSPLFLDFLEGKTDFPCTAWGIPNYSLFGWQRPCYLMSDGYV
                     PTYRQLVEETDWDKYGRGKDPRCDNCMAHCGYEPTAVLATMGSLKESLRAARETAAGSK
                     R"
     gene            18151..19317
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="BV401_RS35650"
                     /old_locus_tag="BV401_35720"
     CDS             18151..19317
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534474.1"
                     /locus_tag="BV401_RS35650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35720"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_079259578.1"
                     /transl_table=11
                     /translation="MSSAEPIALGLPAMPDRPLAPRRVSRRIQVGSVAVGGDAPVSVQS
                     MTTTVTADVGATLQQIAELTASGCQIVRVACPSQDDADALPVIAKKSQIPVIADIHFQP
                     KYVFAAIDAGCAAVRVNPGNIRQFDDKVREIARAASDAGVPIRIGVNAGSLDRRLLEKY
                     GKATPEALVESALWECSLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAQCDYPLHLGVT
                     EAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEVKVGMQILESLNLRQRRLEI
                     VSCPSCGRAQVDVYKLADQVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGK
                     GQIFVKGEVIKTVPESKIVETLIDEAMNIARRMEDEGVPSGTPDVTVG"
     gene            19341..21293
                     /gene="dxs"
                     /locus_tag="BV401_RS35655"
                     /old_locus_tag="BV401_35725"
     CDS             19341..21293
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056072.1"
                     /locus_tag="BV401_RS35655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35725"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_079259579.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 4.7e-110,
                     bitscore: 366.0, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFLENIRGPHDLTALTGEELEALAQEIREFLIKAVARTGGHLGP
                     NLGVVELSIALHRVFDSPADRILWDTGHQSYVHKLLTGRQDFSKLRHKGGLSGYPSRAE
                     SEHDIIENSHASTVLGWADGLAKANEVRGGTDHVVAVIGDGALTGGMAWEALNNIAAAR
                     DRPLVIVVNDNERSYSPTIGGLANHLATLRTTDGYERFLAWGKEVLQRTPVVGQPLYGS
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDTEAVESALRRAKRFHGPVLVHCLTEK
                     GRGYRPALEDEADRFHTVAAMDPLTCAPLTPSGGRSWTSVFGEEMVRIGAERPDVVALT
                     AAMLHPVGLAGFAEAYPERVWDVGIAEQHAAVSAAGLATGGLHPVLAVYATFLGRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGTDGPSHNGMWDMSVLQVVPGLRIAAPRDADQLRAQL
                     REAIDVADAPTVIRFPKESVGEPIPAIDRVGGMDVLRRGEDVLLVAAGVMADVALRAAE
                     LLAGRGIGCTVVDPRWVKPVDPELPGLAARHRLVAVVEDNVRTGGVGAAVAQTLCDAEV
                     DLPVRTFGIPETFLAHAKRGEVLADIGLTPAEIAGRIGAALTRIDASRPERAGATAGAR
                     TAAGGRTAAAKESQA"
     gene            21290..22696
                     /locus_tag="BV401_RS35660"
                     /old_locus_tag="BV401_35730"
     CDS             21290..22696
                     /NRPS_PKS="Domain: Aminotran_3 (48-370). E-value: 8.5e-89.
                     Score: 289.8. Matches aSDomain:
                     nrpspksdomains_BV401_RS35660_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056073.1"
                     /locus_tag="BV401_RS35660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35730"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_069869652.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.3e-86, bitscore:
                     287.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAEQQRRSGFDLGKLLAERASERYDLHTRHLNHQLPRMLHTIG
                     FDKVYERAEGAYFWDDEGQDYLDMLAGFGVMGLGRHHPVVRKALHDVLDADLADLTRFD
                     CQPLPGLLAERLLAHAPHLDRVFFGNSGTEAVETALKFARFVTGKPRVLYCAHAFHGLT
                     TGSLSVNGEDGFRKGFAPLLPDTAIEMGDLDALERELARGDVAGFVVEPIQGKGVHETP
                     PGFLRAAQELLHRHKALLIVDEVQTGLGRTGDFFAYQHEDGVEPDLVCVAKALSGGYVP
                     VGATLGKDWIFRRVYSSMDRVLVHSASFGSNAQAMAAGLAVLAVMEDEEVVANARRTGE
                     LLRDRLAALVDRYELLHDVRGRGLMIGIEFGRPSSLGLRSRWAMLQTARKGLFAQMVVV
                     PLLRRHRILTQVSGDHLEVIKLIPPLIIGEREVDRFVEAFTAVMDDAHEGGGLMWEFGR
                     TLVKQAVANR"
     aSDomain        21434..22399
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS35660_Aminotran_3.1"
                     /evalue="8.50E-89"
                     /label="BV401_RS35660_Aminotran_3.1"
                     /locus_tag="BV401_RS35660"
                     /protein_end="370"
                     /protein_start="48"
                     /score="289.8"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDDEGQDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DADLADLTRFDCQPLPGLLAERLLAHAPHLDRVFFGNSGTEAVETALKFARFVTGKPRV
                     LYCAHAFHGLTTGSLSVNGEDGFRKGFAPLLPDTAIEMGDLDALERELARGDVAGFVVE
                     PIQGKGVHETPPGFLRAAQELLHRHKALLIVDEVQTGLGRTGDFFAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFRRVYSSMDRVLVHSASFGSNAQAMAAGLAVLAVMEDE
                     EVVANARRTGELLRDRLAALVDRYELLHDVRGRGLMIGIEF"
     gene            22713..23906
                     /locus_tag="BV401_RS35665"
                     /old_locus_tag="BV401_35735"
     CDS             22713..23906
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056074.1"
                     /locus_tag="BV401_RS35665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35735"
                     /product="serpin family protein"
                     /protein_id="WP_079259580.1"
                     /transl_table=11
                     /translation="MIDATAVRAVNAMTARWARAAVADEGTVLAAAGVWPLLALLAGGA
                     GGPVRQELEGALGVGADAATALGGEVLGALDGMAGVEAATGLWTRRDLPIRSGWEAALP
                     PGVRATLTGDGERDRKELDAWASRRTRGAITEMPVPLTPATLLVLAGALTVRTDWVQPF
                     RPGPLVPRSGPWRDRSLAGLTRFTEDLDGALRVVPDTPAGPLTLSGVAGGNGLDVRLVL
                     GAEGVPGGEVLEAGIGAVAGRYEGRPGSALPPGEAGPGVRVMEVPSRDPTPRMALTTPR
                     FTVRARHDLLRRAGLFGLRTAQDASRGHFPGISPAALALSSGEQSITASFSAEGFWAAA
                     VTAFSLAPGSAPPRRTAKLISVRYERPFGFLAVHRASGLVLTAGWVTEPEAGPATMW"
     gene            complement(23965..24789)
                     /locus_tag="BV401_RS35670"
                     /old_locus_tag="BV401_35740"
     CDS             complement(23965..24789)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056075.1"
                     /locus_tag="BV401_RS35670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35740"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_069869654.1"
                     /transl_table=11
                     /translation="MPQQSQSPQVPQAETPLVGVRNFRDLGGLPAADGRRVRPGVLFRS
                     GHLAHATEADTAFLDALGLHTIFDFRNAADIKLEGPDVTLRGVRNVNLPLSDPADGAGF
                     WTMVREGDLKTLRELLSEGRAEKRMIGSYRSIITTRLVEHGRILSDMAEDSSPVLMHCS
                     AGKDRAGLSIAVTLLALGVDQETIEADYLESAAAHRRYKIWRKGDPSDSSDPMSPEVMA
                     LLLPLFDARAEYLAAAFATIEETWGGTERYLAEGLGLDPERRERLRERLLTG"
     misc_feature    complement(24928..24942)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.5"
                     /tool="antismash"
     gene            25109..25906
                     /locus_tag="BV401_RS35675"
                     /old_locus_tag="BV401_35745"
     CDS             25109..25906
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713864.1"
                     /locus_tag="BV401_RS35675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35745"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_079259581.1"
                     /transl_table=11
                     /translation="MADDKERFSNGSIGSYAAVGDSFTEGVGDPGPDGVFVGWADRLAV
                     LLSDQRPQDDFRYANLAVRGRLLDQIVAEQVRRAIELGPDLVTFCAGGNDILRPGSDPD
                     DVAERYEAAVADLRAQVGTVLLCTGFDTRGVPVLRHLRGKIATYTAHVRAIADRHGCPV
                     LDLWSLRSVQDRRAWDADRLHLSPDGHTRVALRAGQVLGLDVPADPDQPWPPEGQRTAA
                     EVRRDNIHWAREYLVPWIGRRLRGESSGDHVEPKRPNLLPLRH"
     gene            complement(26041..26421)
                     /locus_tag="BV401_RS35680"
                     /old_locus_tag="BV401_35750"
     CDS             complement(26041..26421)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561024.1"
                     /locus_tag="BV401_RS35680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_35750"
                     /product="ATP-binding protein"
                     /protein_id="WP_069869858.1"
                     /transl_table=11
                     /translation="MFRLPALSTSVGEARRHVVRRLRSWGIDQDTLDSAELIVSELFTN
                     AVRHTSSEEVRCSLQLIGTRLRLEVADQGCARTVPEARSVSADQEGGRGLMLVEALSEA
                     WGVRPNQGGAGRAVWAYLAVSV"
ORIGIN
        1 acgacgagcg ggtgcggctg cggtccgcgg tgaagtcgcg ggacggcttc ttcacgacct
       61 tctgtatcag cccgtactcc cgctatatcg cccgctggtg cgcccggcgc gggctgaccc
      121 ccaaccaggt caccaccgct tccctgctca ccgcgctcat cgcggcggcg tgcgccgcca
      181 ccggcacccg gcccgggttc gtctcggccg gtgtgctgct gatcgcctcg ttcgtgctcg
      241 actgcaccga cggacagctg gcccgctact cgctccagta ctccacgctc ggcgcctggc
      301 tggacgccac gttcgaccgg gccaaggagt acgcctacta cgcgggcctc gccctcggcg
      361 ccgcccgcgc cgacggcgat gacgtctggg cgctggcgct gggcgcgatg gtgctccaga
      421 cctgccgcca tgtcgtggac ttcgccttca acgaggccaa ccacgacgcc accggcaaca
      481 ccagccccac cgccgccctc tccggccgcc tggacagcgt cggctggacg gtctgggtgc
      541 gccgcatgat cgtgctgccg atcggtgagc gctgggcgat gatcgccgtg ctgacggcgt
      601 tcaccactcc ccgtatcacc ttctatgtgc tgctcgtcgg ctgtgcgctg gccgcctgct
      661 acaccaccgc cggccgggtg ctgcgctcgc tgacccgccg ggccgagcgc accgaccggg
      721 ccgcccacgc cctcgccgag ctcgcggaca ccggtccgct ggccgagctg gtggccaagg
      781 ccgccccccg cgggccgagt tcgtacctcg ccccgctctc cgccgccctc ggcgccgccg
      841 cagtcctggc cggcaccgcg gccgccggtt tcggctcctg ggcgccggtc ggatgcgcgg
      901 tgctctacgc ggtcctcgcg ggcgtcgccg tcgccgcgcc gctcaagggc ccgctcgact
      961 ggctggtgcc gccgctcttc cgcgccgccg aatacggcgt catcctcatc cttgcggctt
     1021 gctcggaggt gaacggcgcc ttgccggcgg ctttcgggct gattgcggcc gtcgcctacc
     1081 atcactacga caccgtgtac cgcatccggg gcggcacggg ggcgcctccg cacctgctgg
     1141 tgcgggcgat cggcgggcac gaggggcgga cggtggcggt cacggccgcc gctgccctgc
     1201 tgcaccaccg gaaccaaggt ttcaccatcg cgttgaccgc tttggcggcg gctctcgcgc
     1261 tggcggtgct caccgagagc atccgcttct gggtgtcctc aggagcaccc gccgtacacg
     1321 acgaaacagg agaacccgca tgatcggcct cgtgctcgcg gccggcgccg gacggcgcct
     1381 gcgcccctac accgacacgc ttcccaaggc gctggtgccg gtgggacccg aggggaagga
     1441 agacgagacg accgtcctcg acctgaccct cggcaacttc gcggagatcg gtctgaccga
     1501 ggtcgccatc gtcgtcggtt accgcaagga ggccgtgtac gagcgcaagg aggccctgga
     1561 gcggaagtac ggcgtgaagc tcacgctgat cgacaacgac aaggccgagg agtggaacaa
     1621 cgcctactcc ctgtggtgcg cccgtgacgc gatccagcac tccgtgatcc tcgccaacgg
     1681 cgacaccgtg cacccggtct cggtcgagaa gaccctgctg gccgcgcgcg gcaacgggca
     1741 gaagatcatc ctcgccctgg acaccgtcaa gcagctcgcc gacgaggaga tgaaggtcgt
     1801 cgccgacccc gacaagggcg tccagaagat caccaagctg atggacccgg ccgaggcgac
     1861 cggtgagtac atcggcgtca ccctcatcga gggcgaggcc gccgccgacc tcgcggacgc
     1921 gctgaagacc accttcgagc gcgacccgga cctctactac gaggacggct accaggagct
     1981 ggtcaaccgg ggcttcaagg tggacgtggc gccgatcggc gacgtcaagt gggtcgagat
     2041 cgacaaccac gacgatctgg cgaagggccg tgaaatcgcg tgcctgtact gacgaggctc
     2101 atcccctcgc cgctcgtcgt cgacatccgc gcgggcgccc tggacgatct cgcgggggtc
     2161 ctcgccgacc agcggatctc cgcctccggc aagctggcga tcgccatcag cggcggctcc
     2221 ggcgccgtgc tgcgcgagcg gctggcgccc gcgctgccgg gcgcgagctg gtacgaggtc
     2281 ggcggcggca ccctggacga cgcgatcaag ctcgccgacc gcatgaagtc ggggcactac
     2341 gacgcggtcg tggggctggg cggcggaaag atcatcgact gtgcgaagtt cgccgcggcg
     2401 cgcatcggcc ttccgctggt cgccgtcgcc accaacctct cgcacgacgg tctgtgctcc
     2461 ccggtcgcga ccctcgacaa cgacgcgggc cgcggctcgt acggggtgcc caacccgatc
     2521 gccgtggtca tcgacctcga tgtgatccgg gaggcgccgg tccgcttcgt ccgctccggt
     2581 atcggcgacg cgctgtccaa cgtctccgcg gtcgccgact gggagctgtc ccaccgcgag
     2641 accggtgaac agatcgacgg gctcgcggcc gcgatggcgc gccaggccgg cgaggccgtg
     2701 ctgcgccacc ccggcggggt cggcgacgac ggcttcctcc aggtgctggc cgagggactg
     2761 gtgctcaccg gcatctccat gtcggtcgcg ggggactccc gcccggcctc cggtgcctgc
     2821 cacgagatca accacgcctt cgatctcctc ttccccaagc gcgccgccag ccacggcgag
     2881 cagtgcggcc tggccgccgc cttcgcgatg cgtctgcgcg gggcgcacga ggagtcggag
     2941 catatggccg aggtgctgca ccggcacggt ctgccggtgc tgcccgagga gatcggcttc
     3001 accgtggacg agttcgtcca ggtcgtggag ttcgctccga agacgcgccc cggccgctac
     3061 acgatcctcg agcacctcga cctgtccacc gacgcgatca gggacgcata cgccgactat
     3121 gccaaagcag tcagtcaaac catcagtggc tgaactccgc ccggtcgtcc accccgaagg
     3181 ggtgaaggac cggcggagcg gtgaacactg ggccgggcgc ctgtacatgc gggagatctc
     3241 gctgcgctgc gaccggtacc tggtgaacac gcgggtcaca cccaaccagc tgacgtatct
     3301 gatgaccgtc ttcggcgtcc tcgccgcccc ggccctgctg gtgccgggga tcgcgggcgc
     3361 cgtgctcggg gtgctgatgg tccagctcta cctgctgctg gactgcgtgg acggcgagat
     3421 agcccggtgg aagaagcagt tctcgctggg cggtgtgtat ctggaccggg tcggcgccta
     3481 cctgtgcgac gccgcggtgc tcgtcggctt cgggctgcgc gccgccgatc tgtggggctc
     3541 cgggcggatc gactggctgt gggcgttcct cggcaccctc gccgcgctcg gcgccatcct
     3601 gatcaaggcc gagaccgacc tcgtcggggt cgcccggcac cagggcggtc tgccaccggt
     3661 caaggaggcg gcctccgagc cgcgctcctc cggtgtggcg ctggcccgca gggcggccgc
     3721 ggcgctgaag ttccaccggc tggtcctcgg gatcgaggca tcgctgctca tcctcgtgct
     3781 ggcggtcgtg gaccaggtgc gcggcgacct gttcttcacc cggctgggcg tggccgtact
     3841 ggccggtatc gccctgctgc aaaccctgct tcacctcgtg tccatcctcg cgtcgagcag
     3901 gctcaagtga gcatgaacac aatgaaggtc ggagcggtcg tcctgacgat gggcaaccgt
     3961 cccgaggagc tgcgcgcact cctggactcg gtcgccaagc aggacggcga cccggtcgag
     4021 gcggtcgtcg tgggcaacgg ctcgccgctg ccaccgctcc ccgagggcgt ccggaccgtc
     4081 gagctgccgg agaacgtggg cattcccgcg gggcgcaatg tcggcatcga ggcgttcggg
     4141 cccggcgggt cggacgtcga tgtgctgctc ttcctcgacg acgacgggct gctgccgggc
     4201 accgacacgg ccgagctgtg ccgtgcggcg ttcgccgccg atccggggct gggcatcatc
     4261 tcgttccgca tcgccgaccc cgacaccggt gtcacccagc gtcgccatgt gccccggctg
     4321 cgcgcctccg acccgctgcg gtcctcccgg gtgaccacct tcctcggcgg tgccaacgcg
     4381 gtccgtaccg cggtgttcca gcaggtcggg gggttgccgg acgacttctt ctacgcccat
     4441 gaggagaccg acctggcctg gcgggcgctg gatgccggat ggatgatcga ttaccggtcg
     4501 gacatggtgc tgcaccatcc gaccaccgcg ccgagcaggc acgcggtcta ccaccggatg
     4561 gtggcccgca accgggtctg gctggcccgg cgtaaccttc ctgcgctgct cgtgcccgtc
     4621 tatctgggcg tctggctgct gctcacactg gccaggcgtc cctcgaaaac cgcacttcgg
     4681 gcctggttcg gagggttcag agaaggctgg aagacaccgt gtggtccacg tcggcccatg
     4741 aagtggcgta cggtatggcg cctgacccga ctgggccgac ctcctgtcat ctgacaagct
     4801 cgtaacgaag agcatcgggc gcgacccggg gcgcggcccc gctcagcgca ccctgaagac
     4861 gaaagtgtca actgtgagcg agactacgca cgacggtgcg gtagccgtga gtggcccgcc
     4921 atcagccgac gacggcctgt ccccggccga gctggcgcag aagtacgggc tgtcggtcag
     4981 tggcgcccgg gtgggccttc gcgagtacat caatcagatg tggggccggc ggcacttcat
     5041 cgtggccttc tcgtcggcca agctcactgc ccagtacagc caggccaagc tgggtcaggt
     5101 gtggcaggtg gcgacgccgc tgctcaacgc ggcggtgtac ttcttcatct tcggcctgct
     5161 gctcaagagc agccgcggta tgccgaacga catgtacatc ccgttcctgg tgacgggggt
     5221 gttcgtcttc accttcaccc aggcgtccgc catggcgggc gtacgggcga tctccgggaa
     5281 cctcgggctg gtgcgggccc tgcacttccc ccgcgcctcg ctccccatct cgttctcgct
     5341 ccagcagctc cagcagctgc tgttctcgat gatcgtgctg gtcgtcgtgt tgctgggatt
     5401 cggtcactac ccggccttct cctggctgct gatccttccc acgctggcgc tccagttcgt
     5461 cttcaacacc gggctttcgc tgatcatggc tcggctgggg gccaagaccc cggacctcgc
     5521 ccagctgctg cccttcatcc tccgtacctg gatgtacgcg tccggtgtga tgttcccgct
     5581 ggcccgtacg ctggagcacg ccggggcgag caagtggatc tcggacgcca tgctggggaa
     5641 cccggccgcc gtgtacatgg acctgatgcg gtacgcgctg atcgacgact acaccgcggc
     5701 caacctgccg ccgcatgtct gggcgctggc cctgggctgg gcggttctct tcggcgccgg
     5761 tggctttgtg tacttctgga aggcagagga gcagtacggc cgtggctgag cagactctcg
     5821 acaagggtgc caaggccgct caggcggagc aggccggcaa ggccgagcag gccgcccagg
     5881 cggcttccgc acggtcgcgg gtgcccaccg tcgtcgcgga cgacgtccac atcgtctacc
     5941 gcgtcaacgg cggccccaag gggaagggca gcgccaccgc cgccctcagc cgcatcctgc
     6001 gccgcaaggg cgccccgggg atgcgcgagg tgcacgccgt gcgcggggtc accttcgtgg
     6061 cgtacaaggg cgagtcgatc ggtctgatcg ggtcgaacgg ctccggtaag tccacgctac
     6121 tcaaggccgt cgcggggctg ctgcccaccg agcgcggcaa ggtctacacc gacggccagc
     6181 cgtcgctgct cggggtgaac gcggcgctga tgaacgacct caccggtgag cggaacgtga
     6241 ttctcggcgg tctggccatg gggatgtccc gtgagcagat ccgggatcgc taccaggaca
     6301 tcgtggactt ctcgggcatc aacgagaagg gtgacttcat caccctgccg atgcggacct
     6361 actcctccgg tatggcggcc cggctgcgct tctccatcgc cgcggccaag gaccacgatg
     6421 tgctgatgat cgacgaggcg ctggccaccg gtgacaggaa gttccagaag cgctccgagg
     6481 cccgcatccg cgagctccgc caggaagccg gcacggtctt cctcgtcagc cacaacaaca
     6541 agtccatccg ggacacttgc gaccgggtgc tgtggctgga gaagggcgag ctgctgatgg
     6601 acggcccgac cgacgaggtc atcaaggcgt acgagaagga gaccggcaag tagccgtttc
     6661 gccaacaccg gtctcataga cgacagggcc ccgccggaca acccggcggg gcttcgtcgt
     6721 ccaccgcgag ggccggaggc tgtgccggct gggctcggcg gccccgcagc tcggcctcaa
     6781 ggcagctggc ccactcgccc gcgccggagg ccgcccacgc cctgaggatg ccgatggggt
     6841 gatcttcgct cgacgtcacc gacgaggagt ccatggccac cgcggtcgcc aaggccgagg
     6901 cggaacacgg cgcggtcggg gcgctggtca acagcgcggg ctacgccatg tcgggctgta
     6961 tcgaggaagc ctccatggcc gaggtgcgcg agcagttcga gaccaatgtg tacgggctgg
     7021 tccggctcag ccaactggtg ctgcccggga tgcgcgccca cggcggcggc accatcgtca
     7081 acatcccctc cgtcttcggc cgttacgccg tccccggctc gggcttctac aacgccacca
     7141 agcacgccgt ggaggcgctc agtgactcgc tgcgcaacga ggtggccgac ttcggcgtgc
     7201 gggtcgtcct ggtcgagcca ggaccggtgc gcaccacccg tttcggcgcc acctacgtgg
     7261 ccaatctgcg gccggtgagc cggacgtacg agaccttccg ccgggagagc gccgagtact
     7321 tcgaggcgat ctacaccggc agccgccgca ccctggcggg cagcttcgcc atccagcccg
     7381 acgatgtggc ccggagggtg gcgagggtgg tggccaaggg cgtccgcggc ggcagggcgc
     7441 gcgcccgcta ccccgtcggt caattgccgc ccacccggcg ggccatcaag gagcggccgc
     7501 ggatggcgta tctcccgttc ggctcggggc cggtgaccgc gcgtgagcgc ggcaccgccg
     7561 cgctccggcc gtcccggcgc accgcccccg ccgaatccgc cgcctgcccc caccgacctt
     7621 gaggccccgc cgtcacccgt cggcgagcgc cgcgcgtccg tagtctgtcg cgcgggcggt
     7681 acggctggta aaaataccgt aaacgccgtt cggggagggc gcgttggcgg atgcgcacaa
     7741 ggtgatgatc acgggcgtgg gcgcactctt ccgccgcgct ccgacagcgg aagcggaatc
     7801 ggagttcccg gccgagtgag ataccgccgg cttccttgat ttcatgcgtt cgctccggcc
     7861 cgggatagcg cggcgggaac ggttgcggat tgaactgctg accgaataga aaccgaacag
     7921 atgtggtaat gggcgcggcc gtcgccgggg ttggggagcc gcggcgggca ggtgttgtcg
     7981 acgggccctg acgcttttcg gggaaagcgt tcctcgccgt gatccggacg ggaatgcgga
     8041 cggtgtacgg gagctctcga agggcgcggc ccgtgggaac cgcccggccc ggtcttctcg
     8101 cgggcgccct gccggtccac cgcgaaagtc cgcaggccgg gtgccggata tgggagacaa
     8161 gggcgatatc gctcatcggt atccgccctt gcatccgccg cttcctattc ggatgggccg
     8221 ggcggtgtga gcggagatcg ccccgggcga accgcgcgga aacgctcccg cgtcgcggcg
     8281 gcatcctccg gctgagccgc ggaaacctcc ggtggccgaa cgccacggcg ccgtcggccg
     8341 caatgccatg acccgttttc cgtgggcgct cgaggcccct gcctgcgggt cgaagtggaa
     8401 agccagtgtc ccgaccggtc ggtttccttt ccgccccgcc caagtggcgg gaacgggacc
     8461 tttccgcacc tccgacgagg cgcacaagaa gtcgatctca cctccgctac gcctgtttac
     8521 cgcagagcgg taccacgtat ggcggtcagc ggttccccgg ccgcttaccg gatcactcgc
     8581 gcgcattcct cccgaatgaa tgtccgacgt atgcaggcac gctcccgcgc gccctccggt
     8641 gacccggacg gtggtcgctg agccatccgg cggggcatcc cgacggatct gtggcagggt
     8701 cggggagcta gcagttgaac cagaggctct gtcaccgccg ctgttcacta aacggaggcg
     8761 ctgtatcgtg tgcgtgtacg ccgggttgtc gagcggcgca gcatcaggga gggggacgcg
     8821 tgtcgccagg ggaagcgcac gtcgcaccgt actcacggcg cgagcggctg cgcatcgcga
     8881 ccatccgtga aatcaaggac gtcgcccgga cgctcctggt tcaggagggc ccggaaaatg
     8941 tgaccatccg ggccatcgcg cgtgagatgg gcatgaccgc gcccgccgtc taccgctact
     9001 tcagcagccg ggacgcgctg atcctccagc tgcgtgtgga catcttcgag gagatggccc
     9061 gtttcatgcg cggggtcctc ggccagcatc ccgaggagga gccgggccgc cggtggatca
     9121 gcggtgcccg ggcgctgcgg gtctgggcga tcaagcaccc ccatgagttc gggctgatcc
     9181 tcggcccgtg ggccccgggg ctcggccgtg aggagaccaa gccggagcgc catatgagct
     9241 gggtcttcgg ctcggtcttc tccgatctgg tcgccgatct gtggcgggtg cggggcttcc
     9301 ccgccccgga ggtcgaggag ctcgaccccg ggctcgcgcg cacgctcacc gtgctcagcg
     9361 aggaccagga cgtcgacatg cccccgggag ccatcgccgt gatgctccgc tgctgggtgc
     9421 ggctgtacgg ggtgatctcc atggaggcgc tgggccatat gtccttcgcg ctctccgagg
     9481 gccagcactt cttcgagttc gagctgcgcg atctgtgccg ggtgctggat atctccgagt
     9541 tctacgaaga ggtcgtctga gatcacccga aagccccccg gagaccggtc cgggggcgtt
     9601 cgccggtcac ccgcccggcg ccacttcgga ggtcacatcg gggtatcgcc ccgtacacct
     9661 gtacaccgag aggcgtaagc tgtgccagtg cctgtccgga tcatgccgga gccgggccct
     9721 tgtcccctgt tcgggggctc ggggccggag tccgttgaca agacggagcg gcgtgtccgg
     9781 atcgtgccga ccctggtaac cggtgtagaa cgggggatgt gacggcattg gccacacggc
     9841 ccatctccag cgctcccgcg gggcccggtc gccgggaccc aggtggcgtc ctgggtctcg
     9901 cccgtacgcc tggctgtcca cggtgagcgt ggaggacgag cgcagcgggt cctataccac
     9961 gtcgagcagc cggagcggcg ggcaggaagc cgcccgtgcc gtgctcgaca aggccgccca
    10021 cgagaacttt cccgtggctc ccttcttcct cccccgtgcc tggcgcaccg atctgatggc
    10081 cgtttacggc tacgcccggc tggtcgacga catcggcgac ggcgatctgg cccccggcgg
    10141 cgccgacgcc gaactgctcg gtctcgaccg cgaccgggcg gacgacgcgc tcgcgatgct
    10201 ggacgcgttc gaggccgacc tccaccgggt cttccggccc gccggggagc cgcgccatcc
    10261 gctgctgcgg gcgctgcgcc ccaccgtcca ccgccatggg ctcacccccg agcccttcct
    10321 cggcctgatc gaggccaacc gccaggacca gagcgtccgg cggtacgcca cctaccagga
    10381 tctcctcggc tactgcgagc tgtccgccaa cccggtcggg cggctcgtcc tcggcatcac
    10441 cggcaccacc agccccgagc ggatccgcca ctcggacgcc atctgcaccg cccttcagat
    10501 catcgagcat gtgcaggacg tggccgagga cctccgcagg gaccgcatct acctgcccgc
    10561 cgaggacatg aaacgcttcg gcgtgaccga ggccgacctc gccgccccca ggggcggcgt
    10621 acggttgcgc gccctggtcg cgaaggaggc ggaacgcgcc gcggccctgc tgaatgaagg
    10681 cacccccctg gtgggtagcg tccacggcag gctcaaggtg ctgctcgccg gattcgtggc
    10741 cggggggcgg gccgccttgc gggcggtcgc ggccgcggga catgacgtac tccctggacc
    10801 gcccaggccc accaagctca gcctgctgcg cgaggtgggg gcgacactgc gaagagaggg
    10861 gtgagccgga ccgtgaaggg atctccgcac gcgtccgcgc cagtactcgc ggcgtaccgc
    10921 tactgcgagg ccgtgaccgg ccaccaggcc cgcaacttcg cctacggcat caggctgttg
    10981 ccgacggaga agcgccatgc gatgtcggcc ctgtacgcct tctcccgccg ggtcgacgac
    11041 atcggggacg gccccctcga cccggaggaa aagcgcaccc ggctggcgga cacccgtgcc
    11101 ctgctggacc ggatgcggag cggcgggatc gaggaggacg acaccgaccc ggtcgccgtc
    11161 gccgtctccc atgccgcgca ccgcttcccg atcccgctgg acgcgttgga cgagctgatc
    11221 gacggcgtgc tgatggacgt ggccgggcag acctacgaga cctgggacga cctcaaggtc
    11281 tactgccgct gtgtggcggg cgccatcgga cggctgtcgc tcggcgtctt cggcaccgcc
    11341 cccggcaccg gccacagcga ggacgagctc gagcgcgccc cgtactacgc cgacaccctc
    11401 gggctcgccc ttcagctgac caacatcctc cgggacgtcc gcgaggacgc cgccaccggg
    11461 cgcacctatc tgcccgccga cgacctggcc aaattcggct gcgccaccgc gttccgcagc
    11521 tccaccgcac cgcccgacgc cgatttcacc ggtctggtcc acttcgaggt gcgccgggcc
    11581 agggccctgt tcgccgaggg cttccggctg ctgccgctgc tggaccggcg cagcggggcg
    11641 tgtgtgtccg ccatggcggg catctaccgc agactcctgg accggatcgc caaggacccc
    11701 gcggccgtcc tgcgcggccg cgtctcgctg cccggacatg agaaggcgta tgtggcggtg
    11761 cgcgggctgg ccggtctcga cgcccgcgcc gtcgagcgcc gcggcaccgg gagggcggtg
    11821 tgacccactc ggccctggac cccgccccgc ccgccgggcc acgcccccgc gggcgcgccg
    11881 cgctggtgat cggcggcggg ctcgccggta cggcggcggc gctcgcgctg gccgacgccg
    11941 ggctccgggt caccctgatc gaggggcgcc cccggctggg gggcctcgcc ttctccttcc
    12001 accgctcctc cccggcgggc gtgctgagcg tcgacaacgg ccagcatgtg tacctgcgct
    12061 gctgcgacgc ctaccagtgg ttcctggagc gggtcggcgc cgcccgactc gccccgctcc
    12121 agggccggtt ggacgtcccc gtcctggacg cccgggggcg gagcgggcgg cggctcggcc
    12181 ggctgcgccg caccgccctg ccggtgccgc tccatctgtc cgcgagcctg gccacctacc
    12241 cccatctctc cctcgccgag cgcgcccagg tgggccgcgc cgcgctcgcc ctggggcggc
    12301 tcgacccccg cgacccggag ctggacgggg tggacttcgc cggctggctg cgccgccacg
    12361 gccagtcgcc gcgcgccgtc gaggcgctgt gggacctggt cggcgtggcc acgctcaacg
    12421 ccaccgcttc caacgcctcg ctcggcctgg ccgcgatggt cttcaagacc gggctgctct
    12481 cccggcccgg cgccgccgac atcggctggg cccgcgcccc gctcggcgag ctgcaccaca
    12541 cccacgcccg ccgcgccctg gacgcggcgg gcgtgacgac cgagctgcgc acccgggtga
    12601 ccggcgtcac ccgcaccccc gagggccgct ggagcgccgc caccgccggg cggccggcgg
    12661 acggctcgcc ggtcgaggcg gacgttctcg tgctggccgt accgcagcgc gaggcgcacg
    12721 ccctgctgcc cgacggcgcc ctgaaggacc ccggccggct gctgcgcatc ggctccgcgc
    12781 ccatcctcaa tctgcatgtg atctacgacc gcacggtgct gcgccgtccg ttcttcgccg
    12841 cgatcggctc ccccgtccag tgggtcttcg accgtacgga cgcctcgggg ctgagggacg
    12901 cgcccggggc cggggacagc cagtacctgg cggtgtcgca gtccgccgcg tacgacgaca
    12961 tcgaccgccc ggtggccgag ctgcgcgccc gctatctgcc cgagctggag cggctgcttc
    13021 cggtcgcccg cggtgcccgg gtgcgggact tcttcgtcac ccgggagcgc accgccacct
    13081 tcgcgcccgt ccccggcgtc ggcctcctgc ggccctccgc cccgaccgac gcgcccggcc
    13141 tctacctggc cggtgcgtgg accgccaccg gctggcccgc gaccatggag ggcgccgtgc
    13201 gcagcggtct ttccgcagcc cgcaccgccc tcaccgacct cggccgccca catgtgaacc
    13261 ctctccccgc cctcggcggg gggacgccca aggaggtggc atgagcacca ccaccaaaaa
    13321 cagaggagag accgtgacct cggcgacccc agctgccgac accgcaggcg tcatgccgct
    13381 gctggagcgc ggccgcacgc tcgccacgcc ggtgctgcgc gccgccgtgc accggttggc
    13441 tccgcccatg aacaccgtcg ccgcttacca cttcggctgg atcgacgccg agggcaaccc
    13501 ggcggagggc gacggcggca aggccgtgcg ccccgcgctc gccctgctgt ccgccgaggc
    13561 ggcgggcgcc gcccccgagg ccggggtgcc cggcgcggtc gcggtcgagc tggtgcacaa
    13621 cttctcgctg ctccatgacg acctgatgga cggggacgag cagcgccgcc accgcaacac
    13681 ggtgtggaag gagcacggcc cggcccaggc catcctggtc ggtgacgccc tgttcgccct
    13741 ggccaacgag atactgctgg agatcggcac cgtggaggcc ggacgggcca cccgccggct
    13801 caccgcggcg acccggaaac tgatcgacgg ccaggcccag gacatctcct tcgaacaccg
    13861 cgagcgcgtc accgtcgagg agtgcctgga gatggagggc aacaagaccg gtgccctgct
    13921 cgcctgcgcg gcctccatcg gcgccgtgct cggcggcgcc gacgaccgca ccgccgacat
    13981 cctggagcgc tacggccacc acctgggcct cgccttccag gccgtcgacg acctgctcgg
    14041 catctggggc aacccggagg ccaccggcaa gcggacctgg agcgatctgc gccagcgcaa
    14101 gaagtccctg ccggtggtcg ccgcgctcgc cgcaggcggc cccgactccg agcgcctggc
    14161 ccagatcctc gcggccgacg cgcgcaagcc ggaggaggag ttcgcggact tctcggagga
    14221 agaattcgcc gtccgcgccg cgttgatcga acaagcgggt ggccgggact ggacctctca
    14281 ggaggcccgc agacagcatg cgaccgccat ggaggcgctg ggctcggtgg acatgcccgc
    14341 cgagatccgg gcccggttcg tggcgctcgc cgacttcgtc gtcgtacgaa agagatgatc
    14401 gccatggacc gctagttcgc gttcgcagtc gccggccggc acccagccgg ggtgtcggcc
    14461 gacggaagcc ccaaagacgg cagatgaaca cactgcgagg ggaagccatg acagcgacac
    14521 cgaccgtcca accctccgag tcatccgagt ccaagacctt gagcgtcgcc cgcgaggcga
    14581 cggcccgcgc ggtggagcac ctgctgtccc gccaggacga gcgcggctgg tggaagggcg
    14641 acctggagac caacgtcacc atggacgccg aggatctgat gctccggcag ttcctcggca
    14701 tccaggaccc cgacaccctc gacgccgccg cccgctatct gcgctcccag caggcccccg
    14761 acggcacctg ggccaccttc cacggcggcc cgcccgagct ctccaccacc atcgaggcgt
    14821 atgtcgccct gcggctggcc ggcgacgagc ccgacgcgcc ccatatgacc gccgcctccg
    14881 cctgggtgcg ctcccggggc ggcgtcgcgg ccagcagggt gttcacccgg atctggctgg
    14941 ccctcttcgg ctggtggcgc tgggaggacc tgcccgagct gccaccggag atcatctact
    15001 tcccgaagtg gtttccgctc aacatctacg acttcggctg ctgggcccgg cagaccatcg
    15061 tgcccctcac cgtcgtctcg gccaaacgcc ccgtgcgccc ggcccccttc cccctcgacg
    15121 agctccacac cgacccccgc aagcccaatc cgccgcttcc gcaggccccc atcgccacct
    15181 gggacggcgt cttccagcgg ctggaccggg cgctgcacgc ctaccacaag gtcgccctcc
    15241 gcccgctgcg ccggtccgcg ctgcgctcct gcgcccgctg gatcgtggag cggcaggaga
    15301 acgacggctg ctggggcggt atccagccac ccgccgtcta ctccgtcatc gccctccatc
    15361 tgctcggcta cgacctcgac caccccgtga tgcgcgccgg tctggagtcg ctcgaccggt
    15421 tcgcggtgtg gcgcgaggac ggcagccgga tgatcgaagc ctgtcagtcc ccggtctggg
    15481 acacctgtct ggccgccatc gcgctcgccg acgccggact cgccccggac catccggcgc
    15541 tggtcaaggc cgccgactgg atgatggccg agcagatcga ccggcccggc gactggtcgg
    15601 tccggcggcc gggactgccc tccggcggct gggcgttcga attccacaac gacaactacc
    15661 ccgatatcga cgacaccgcc gaggtcatcc tggcgctgcg ccgggtcgac caccccgagc
    15721 ccgcgcggat cgaggcggcc gtgcggcgcg ccatgcgctg gaccctgggc atgcagtcca
    15781 agaacggggc gtggggcgcg ttcgacgtcg acaacaccag cccgctgccc aacaagctgc
    15841 cgttctgcga cttcggcgag gtcgtggacc cgccgtcggc cgatgtcacc gcgcatgtcg
    15901 tggagatgct cgcacacgag ggcaggacgt acgacgcccg cacccggcgc ggtatctcct
    15961 ggctgctgtc cgagcaggag ccgagcggcg cctggttcgg ccgctggggc accaactacg
    16021 tctacggcac cggctcggtc gtccccgcgc tgatctccgc gggcgtcccc gcctcccatc
    16081 cggcggtccg ccgggccgtc cgctggctgg agagcgtcca gaacgaggac ggcggctggg
    16141 gcgaggacca gcgctcctac ctcgacgccg agtggatggg ccggggcgcc tccaccgcct
    16201 cccagaccgc gtgggcgctg ctcgcgctgc tcgcggcggg ggagcggggc ggcgcggccg
    16261 tcgagcgcgg ggtcacctgg ctcgccgaga cccagcggga ggacggctcc tgggacgagc
    16321 cgtacttcac cggcaccggt ttcccctggg acttctccat caactaccac ctgtaccgtc
    16381 aggtcttccc ggtcacggca ctcggccggt ttgtccacgg cgagcccacc ggggcgcgac
    16441 cgcggagcag ttgatgtccg ccgatccggc cccggaggcc ggtggtgcgc cgctgctgat
    16501 cgcctgcgcg ctcggcatcg agtggttcgc cctgcgcggc gccggccccg gcgccgccgg
    16561 ggaggtgacc gtgctgcgca ccggtatggg gccgcagtcg gccgagcgcg ccgtgacccg
    16621 ggcgctgacc gccgggtccg gggagtggcg caccgccgtc atcgccaccg gcttctgcgc
    16681 cgggctggcc cccgggatgc acccggggga cctcgtcgtc gccgacgaga cccgcgatcc
    16741 ggcgggccgc accgtgtgca ccggcacccg gatcctcgcc gacgccctgt cacggccgct
    16801 tccgggcggc ccccgccgtg ccgtgcacat cggcccggtc gtgggctccg accatgtggt
    16861 gcgcggtgcg gagcggaccg cgctgcaccg caccggagcc atcgcggtgg acatggagtc
    16921 cgccgcgacc ctgcgcaccg ccgtcggcca cggcgtccgt ccggttgcgg ccgtccgggt
    16981 ggtcgtggac gctcctgaac atgaactcgt ccgaattggc accctgcgcg gtggaatatc
    17041 ggctttccgg gttctacgaa ccgttcttcc cgctttcttt cactggcacc gttcttcgct
    17101 gctcccagga ggtgagctag atggccatgc ctctccgcca gaccatccgg gtcgcgacgt
    17161 atctctttga acagaagatg atcaagcggc gggacaagtt cccgctgatc gtcgagctcg
    17221 agccgctctt cgcgtgcaat ctcaaatgcg agggctgcgg aaagatccag catccggccg
    17281 gggtcctcaa gcagcgcatg ccggtcgccc aggcggtggg cgcggtgctg gagtcgggtg
    17341 ccccgatggt gtccatcgcg ggcggtgaac ccctgatgca tccgcagatc gacgagatcg
    17401 cacggcagct ggtggagcgg aagaagtatg tcttcctctg caccaacgcg atgctgttgc
    17461 ggaagaagat gcatctgttc accccctccc cgtacttcgc cttcgcggtg cacatcgacg
    17521 ggctgcggga gcggcatgac gaatcggtcg cgaaggaggg ggtgttcgac gaggcggtgg
    17581 aggccatcaa ggaggccaag cggcgcggct tccgggtcac caccaattcc accttcttca
    17641 ataccgacac cccccagacc atcgtggacg tcctcgactt cctcaatgac gagctcgagg
    17701 tggacgagat gatgatctcg cccgcctacg cctatgagaa ggcgcccgac caggagcact
    17761 tcctgggcgt ggagcagacc cgcgagctgt tccggaaggc gttcgccgga ggcaaccgcc
    17821 gccgatggcg gctcaaccac agcccgctct tcctcgactt cctcgaaggc aagacggact
    17881 tcccgtgcac cgcctggggc atccccaact actccctctt cggctggcag cgaccctgct
    17941 acctgatgag cgacggctat gtcccgacct accgccagct ggtcgaggag accgactggg
    18001 acaagtacgg ccgcggcaag gacccgcgct gcgacaactg catggcccac tgcggctatg
    18061 agcccaccgc ggtcctggcg accatgggct ccctcaagga gtcgctgcgc gccgcccgtg
    18121 aaaccgccgc cggaagcaaa aggtgactcg atgagttcag cggaaccaat cgcactcggc
    18181 ctgcccgcca tgccggacag gccgctcgcg ccgcgccggg tctcgcgccg gatccaggtg
    18241 gggtcggtgg ccgtgggtgg cgacgctccg gtctcggtgc agtcgatgac gacgacggtg
    18301 acggcggatg tcggtgcgac gttgcagcag atcgcggagt tgacggcgtc ggggtgtcag
    18361 attgtgcggg tggcgtgtcc ttcgcaggat gatgcggatg cgttgccggt gatcgcgaag
    18421 aagtcgcaga ttccggtcat tgccgacatt cattttcagc cgaagtatgt gtttgcggcg
    18481 attgatgccg ggtgtgcggc ggtgcgggtg aatccgggga acatccggca gttcgatgac
    18541 aaggtgaggg agatcgcgcg ggcggcgtcg gatgcgggtg tgccgattcg tatcggggtg
    18601 aacgcggggt cgttggacag gcggttgctg gagaagtatg ggaaggcgac tccggaggcg
    18661 ttggtggagt cggcgttgtg ggagtgctcg ctgttcgagg agcatgggtt ccgggatatc
    18721 aagatctcgg tgaagcacaa cgatccggtg gtgatggtca atgcgtaccg tcagttggcg
    18781 gcgcagtgtg attacccgtt gcatctgggt gtgacggagg cgggtccggc gttccagggg
    18841 acgatcaagt cggcggtggc gttcggtgcg ctgctgagtg aggggatcgg ggacacgatc
    18901 cgggtgtcgt tgtcggcgcc tcctgcggag gaggtgaagg tcgggatgca gattctggag
    18961 tcgttgaatc tgcggcagcg gcggttggag attgtttcgt gtccgtcgtg tgggcgggcg
    19021 caggtggatg tgtacaagct ggcggatcag gtgacggcgg gtctggaggg gatggaggtt
    19081 ccgctgcggg tggcggtcat ggggtgtgtg gtgaacggtc ccggtgaggc gcgtgaggct
    19141 gatctgggcg tcgcttccgg gaatggcaag gggcagatct tcgtcaaggg cgaggtcatc
    19201 aagaccgtgc cggagtcgaa gatcgtggag accctgatcg acgaggccat gaacatcgcg
    19261 cggcgcatgg aggacgaggg ggtcccgtcg ggtaccccgg acgtcaccgt gggctgatac
    19321 accgaggagg ggaaccgacc atgccgtttc tggagaacat ccggggcccg cacgacctca
    19381 cggcgctcac cggtgaggaa ctggaggcgc tcgcccagga gatcagggag ttcctgatca
    19441 aggcggtggc caggaccggg ggccatctgg gaccgaacct cggcgttgtc gagctgtcca
    19501 tagccctgca ccgcgtcttc gactcgcccg ccgaccgcat cctgtgggac accgggcacc
    19561 agtcctacgt ccacaagctg ctcaccggcc gtcaggactt ctccaagctc cgccacaagg
    19621 gcgggctgtc cggctatccg tcacgggccg aatccgagca cgacatcatc gagaacagcc
    19681 atgcctccac cgtgctgggc tgggccgacg gcctcgccaa ggccaacgag gtgcgcggtg
    19741 gcacggacca tgtggtcgcc gtcatcgggg acggggcgct gaccggcggg atggcctggg
    19801 aggcgctcaa caacatcgcc gccgcccggg accgccccct cgtcatcgtc gtcaacgaca
    19861 acgagcgctc ctactcgccg accatcggcg gactcgccaa ccacctcgcc accctccgca
    19921 ccaccgacgg ctatgagcgc ttcctggcct ggggcaagga ggtgctccag cgcacccccg
    19981 tggtcggcca gccgctgtac ggatcgctgc acggcgccaa gaaggggttc aaggacgcct
    20041 tcgcgccgca gggcatgttc gaggacctcg ggctgaagta cgtcggcccc atcgacggcc
    20101 atgacaccga ggcggtcgag tcggcgctgc gccgcgccaa gcggttccac ggcccggtcc
    20161 tcgtccactg cctcaccgag aagggccggg gctaccggcc cgcgctggag gacgaggcgg
    20221 atcgtttcca caccgtcgcc gcgatggacc cgctcacctg cgcgccgctg accccctccg
    20281 gcggccgctc gtggacctcg gttttcggcg aggagatggt gcggatcggc gccgagcggc
    20341 ccgatgtggt cgccctcacc gccgccatgc tgcaccccgt gggcctcgcc ggcttcgccg
    20401 aggcgtaccc ggagcgggtg tgggacgtgg gcatcgcgga gcagcacgcg gcggtctcgg
    20461 cggccgggct cgccaccggc ggactccacc cggtcctcgc cgtctacgcc accttcctgg
    20521 gccgcgcctt cgaccagctg ctcatggatg tcgccctgca cagatgcggg gtgaccttcg
    20581 tgctggaccg ggccggtgtc accggcaccg acgggcccag ccacaacggc atgtgggaca
    20641 tgtccgtcct ccaggtggtg ccggggctgc ggatcgccgc cccgcgcgac gccgaccagc
    20701 tccgcgccca gctgcgggag gcgatcgacg tggccgacgc gccgaccgtc atccgcttcc
    20761 ccaaggagtc ggtgggggag ccgattccgg cgatcgaccg cgtcggcggg atggatgtgc
    20821 tgcgccgggg cgaggacgtc ctcctcgtcg cggccggggt gatggccgac gtcgcgctgc
    20881 gcgccgccga gctgctggcc gggcgcggca tcggctgtac ggtggtcgat ccgcgctggg
    20941 tcaagcccgt cgaccccgag ctgcccggac tcgccgcgcg ccaccggctg gtggcggtcg
    21001 tcgaggacaa tgtgcgcacc ggcggggtgg gcgcggcggt cgcccagacc ctgtgcgacg
    21061 ccgaggtcga cctgccggtg cggacgttcg gcatccccga gacgttcctg gcccatgcca
    21121 agcgcggtga ggtgctcgcc gacatcgggc tcacccccgc cgagatcgcg ggccggatcg
    21181 gggcggccct gacccgtatc gacgcgtccc gcccggagcg ggcgggcgcc actgccgggg
    21241 cccgtaccgc cgccgggggc cgtaccgcag ccgccaagga gagccaggca tgacagcagc
    21301 cgagcagcag cggcgttcgg gcttcgatct gggcaagctc ctggccgagc gggcgtcgga
    21361 gcggtacgac ctgcacaccc ggcacctcaa ccaccagctg ccccggatgc tgcacaccat
    21421 cggcttcgac aaggtctacg aacgagccga gggcgcgtac ttctgggacg acgagggcca
    21481 ggactacctc gatatgctcg ccggcttcgg ggtgatgggc ctgggccgcc accaccccgt
    21541 ggtccgcaag gcgctgcacg acgtcctgga cgccgacctg gccgatctga cccgtttcga
    21601 ctgccagccg ctgcccggtc tgctggccga gcggctgctg gcccacgccc cccatctgga
    21661 ccgggtcttc ttcggcaaca gcggcaccga ggccgtcgag accgccctga agttcgcccg
    21721 ctttgtgacc ggcaagccgc gcgtcctgta ctgcgcccac gccttccacg ggctgaccac
    21781 cggctcgctg tcggtcaacg gcgaggacgg cttccgcaag gggttcgccc cgctgctccc
    21841 cgacaccgcg atcgagatgg gcgacctcga cgcgctggag cgggagctgg cgcgcgggga
    21901 cgtggcgggg ttcgtggtgg agcccatcca gggcaagggg gtgcacgaga ccccgcccgg
    21961 cttcctgcgc gccgcgcagg agctgctcca ccgccacaag gccctgctca tcgtggacga
    22021 ggtgcagacc ggcctcggcc gcaccgggga cttcttcgcc taccagcacg aggacggtgt
    22081 cgaaccggat ctggtgtgcg tggccaaggc actctccggg ggctatgtgc cggtcggcgc
    22141 gaccctcggc aaggactgga tcttcagacg ggtctactcc tcgatggacc gggtgctggt
    22201 ccactccgcc agcttcggct ccaatgccca ggccatggcg gccgggctcg cggtcctcgc
    22261 cgtcatggag gacgaggagg tggtggccaa cgcccgccgc accggtgagc tgctgcgcga
    22321 ccgcctcgcc gcgctcgtgg accgctacga gctgctgcac gacgtccgcg gccgggggct
    22381 gatgatcggc atcgagttcg gccgacccag ctcactgggg ctgcgcagcc ggtgggcgat
    22441 gctccagacc gcgcgcaagg ggctgttcgc acagatggtc gtcgtaccgc tgctgcgccg
    22501 ccatcgcatc ctcacccagg tctccggcga ccatctggag gtcattaagc tgattccgcc
    22561 gctgatcatc ggcgagcggg aagtggaccg tttcgtcgag gcgttcacag cggtcatgga
    22621 cgacgcgcat gagggcggcg gcctgatgtg ggagttcggc cgcactctcg tcaaacaggc
    22681 ggtggccaac cgctgaccgt tgggggaccg gcatgatcga cgcgaccgcc gtacgggccg
    22741 tcaacgcgat gacggcgagg tgggcgcggg cggccgtggc ggacgagggc acggtcctcg
    22801 ccgccgccgg ggtctggccg ctgctggccc tgctcgcggg cggtgccggc ggccccgtcc
    22861 gccaggagct ggagggcgcg ctgggcgtcg gcgcggacgc ggcgacggcg ctcggcggag
    22921 aggtgctcgg ggcgctggac ggcatggccg gcgtcgaggc ggccaccggg ctgtggaccc
    22981 gtcgggacct gccgatccgg tccgggtggg aggccgcgct gccgccgggc gtacgcgcca
    23041 cgctgaccgg ggacggtgag cgcgaccgca aggagctgga cgcctgggcg tcccggcgca
    23101 cccggggcgc gatcaccgag atgccggtgc cgctcacccc cgccaccctg ctggtgctgg
    23161 ctggagcgct cacggtgcgg accgactggg tacagccgtt ccggccgggc ccgctggtgc
    23221 cgaggagcgg accgtggcgg gaccggtcgc tggccgggct cacccggttc acggaggacc
    23281 tcgacggggc gctgcgggtc gtccccgaca ccccggccgg cccgctcacc ctctccgggg
    23341 tcgcgggcgg caacgggctg gatgtgcgtc tggtcctcgg cgccgagggc gttcccggcg
    23401 gcgaggtgct ggaggccggg atcggcgcgg tggccgggcg gtacgagggg cggcccggct
    23461 cggcgctgcc gcccggtgag gcggggcccg gggtccgggt catggaggtc ccgagccggg
    23521 accccacgcc ccggatggcg ctcaccactc cgcggttcac cgtgcgggcg cggcacgatc
    23581 tgctgcgcag ggccgggctg ttcgggctgc gcaccgccca ggacgcctcg cgcggccact
    23641 ttccggggat cagccccgcc gcgctggcgc tgtcctccgg agagcagtcc atcaccgcct
    23701 cgttcagcgc ggagggcttc tgggcggcgg cggtgaccgc gttctccctg gcccccggct
    23761 cggcgccgcc gcggcgcacg gcgaagctga tcagtgtgcg gtacgagcgg ccgttcggct
    23821 tccttgccgt gcaccgcgcc agcggtctgg tgctgacggc ggggtgggtc accgagcccg
    23881 aggccgggcc cgccaccatg tggtgagccc gtagggctcc agggccctac gggctcacgg
    23941 gctcacctgc tcatgggcgc gccgtcagcc ggtgagcagc cgctcccgca gccgctcgcg
    24001 ccgctcgggg tcgaggccga gcccctcggc gagatagcgc tcggtgccgc cccaggtctc
    24061 ctcgatggtc gcgaaggccg ccgccagata ttccgcgcgg gcgtcgaaga gcggcagcag
    24121 cagcgccatg acctcggggg acatggggtc ggagctgtcc gaaggatcgc ccttgcgcca
    24181 gatcttgtag cggcggtggg cggcggccga ttcgaggtag tcggcctcga tggtctcctg
    24241 gtcgactccg agggccagca gggtcaccgc gatggacagc ccggcccggt cctttccggc
    24301 cgaacagtgc atcagcaccg gtgagctgtc ctccgccata tcgctgagga tccggccgtg
    24361 ctcgaccagc cgggtggtga tgatggagcg ataggagccg atcatgcgct tctcggcccg
    24421 gccctcggag agcagctcgc gcagggtctt cagatcgccc tcgcgcacca tcgtccagaa
    24481 cccggcgccg tcggccgggt cggacagcgg cagattgacg ttccggaccc cgcggagcgt
    24541 gacgtccggg ccctccagct tgatgtcggc ggcattgcgg aagtcgaaga tggtgtgcag
    24601 tccgagcgcg tcgaggaagg ccgtgtccgc ctccgtggca tgggcgagat ggccgctgcg
    24661 gaacagcaca cccgggcgta cgcggcggcc gtcggcagcc ggcagtccac cgagatcacg
    24721 gaagttgcgt acccccacca ggggtgtttc ggcctggggg acctgcggcg actgtgactg
    24781 ctgcggcacg ggctctcctt cacgatcggc cgccgacgcg gctcgtcgac aggcggctga
    24841 agctgaccct acgacatggg tgcaacaggc aatcggcctc gcgggaacgc gggcatcggg
    24901 tggccttccg gccctgctcg ggggtggtgg ccggatcgat ccgggcatgc cggcccgacc
    24961 gaccggcggt ggacctccgg tgacctcggc gccgccgcgc tctgcctatt ccgcctttgc
    25021 cgaaactgac caggtgggat agatcacccc acgtcaagcc ctggttacgg tggcgtaagt
    25081 cacgccatcg ggtgaatgat gtcccgacgt ggcagacgat aaggagagat tcagcaacgg
    25141 ttccatcggg tcgtacgcag ccgtcggcga cagcttcacc gagggcgtcg gcgaccccgg
    25201 tcctgatggg gtgttcgtcg gctgggccga ccggctcgcg gtcctgctgt ccgaccaacg
    25261 accccaagac gatttccgct acgccaatct ggccgtacgc ggtcgactcc ttgaccagat
    25321 tgtggctgag caggtgcggc gcgccattga actcggcccg gatctggtca ccttctgtgc
    25381 gggcggcaat gacatcctgc ggcccggcag tgaccccgac gatgtcgccg agcgctatga
    25441 ggcggccgtc gccgacctcc gggcgcaggt gggcacggtg ctgctgtgca cgggcttcga
    25501 caccagaggg gtgccggtgc tgcgccatct acggggcaag atcgccacgt atacggcgca
    25561 tgtgcgggcg atcgccgacc gccatggctg cccggtgctc gacctgtggt cgctgcgctc
    25621 ggtgcaggac cgccgggcct gggacgccga ccggctgcat ctgtcgccgg acggtcacac
    25681 ccgggtcgcg ctgagggccg gtcaggtgct ggggctcgac gtccccgccg accccgatca
    25741 gccctggccc ccggagggcc agcgcaccgc ggccgaggtg cgccgggaca atatccactg
    25801 ggcgcgcgaa tatctggtgc cctggatcgg ccgacgactg cgcggagagt cgtcgggtga
    25861 ccatgtggag cccaagcggc ccaatctgct gccgctgcgg cactgaacgt tccgtgaccc
    25921 gaagcggtcc cggaggaata ggggcagacc cccgttggcg ccccgcggtc gaccacctgg
    25981 tgcgctgtcg ctgcccctat tccctcggca ccgctcgtac gtcgcgtcgt cgccgtgccg
    26041 ctagaccgag accgccagat acgcccagac cgcgcggccg gcgcccccct ggttcggcct
    26101 gaccccccat gcctcggaga gggcctccac cagcatcagc ccacggccgc cctcctggtc
    26161 cgcgctcacc gagcgggcct ccggcaccgt acgcgcgcac ccctggtcgg ccacttcgag
    26221 ccgcagccgg gtgcctatga gctggagcga gcagcgaacc tcctcgctgg aggtgtggcg
    26281 caccgcgttg gtgaacagct cggagacgat caactcggcg ctgtccaggg tgtcctggtc
    26341 gatgccccat gagcgcagcc gccggacgac atgccttctc gcctcgccga cggacgtgct
    26401 cagcgccgga agacgaaaca cgtcgtggcg gggcggagcg accacgatgc cgcc
//
