LOCUS       NZ_CP019458            29384 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 chromosome, complete
            genome.
ACCESSION   NZ_CP019458
VERSION     NZ_CP019458.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6966295
            Orig. end                         :: 6995679
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019458.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29384
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="31"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..29384
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29384
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:19384]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19384
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            835..1272
                     /locus_tag="BV401_RS28585"
                     /old_locus_tag="BV401_28650"
     CDS             835..1272
                     /EC_number="2.1.1.-"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639922.1"
                     /locus_tag="BV401_RS28585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28650"
                     /product="HIT family protein"
                     /protein_id="WP_079258845.1"
                     /transl_table=11
                     /translation="MTTVFSRIIAGELPGHFVWQDPEIVAFLSIAPLRPGHTLVVPRRE
                     VDRWTDVDGALLARCFEVAQAVGQGVRRAWDAPRAGLVIAGFEVPHLHIHVAPVWDMSD
                     FDFSKAKQEEDQSALAEAAAKLRAALLELGYEQARDFGPGV"
     misc_feature    840..858
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            1343..2104
                     /locus_tag="BV401_RS28590"
                     /old_locus_tag="BV401_28655"
     CDS             1343..2104
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714938.1"
                     /locus_tag="BV401_RS28590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28655"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_079258846.1"
                     /transl_table=11
                     /translation="MSWSTREIAELAGTSLRAVRHYHEVGLLEEPERRVNGYKQYGVPH
                     LVRLLRIKRLVDLGFSLNQIAETVDEGEHPGRALRTLDAELAATVERLQRARLELTTLI
                     EQRAPADLPAELTPGEATVLSKTDRSLLLVMARLMNGEQLQTYGALVRNLPAHPVNQEF
                     DELSADAGEHIRQDLVERMVPYLRWLRQDHPDLPDLYTAVSKGKKIIRETMETVLHELY
                     NPAQLDVLHRAHVIVDGSTQPRPGRNATELR"
     gene            complement(2088..2570)
                     /locus_tag="BV401_RS43180"
     CDS             complement(2088..2570)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS43180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158525929.1"
                     /transl_table=11
                     /translation="MGDLIGMGQPAMSRSIVPSFQFCNTNYRGRTPPTRTTARTNSTVS
                     AGPGRSRYHEKRYGRSSGAYPGLHVSGGHAPHDDKRTEIDRCVEQRHCFRVLRSVGEHA
                     ARRDSGPQLGQQGSADCVAGICMGMGLHGHSGVSLTGAAVDGDGMERETGAVNEVR"
     gene            2726..3094
                     /locus_tag="BV401_RS42460"
                     /old_locus_tag="BV401_28665"
     CDS             2726..3094
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="BV401_RS42460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28665"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_202819342.1"
                     /transl_table=11
                     /translation="MPITIRPDDNLRLVRVMCNNCGRINQSAIASPPYIPSETAEDRHE
                     RLIALLATGHTDASAARQLGVSRRTVTYMLRSMMDGLGINNRFQLGIAVGAHSRACAAC
                     PAPREPAMTNAAHNDGRY"
     misc_feature    complement(2765..2781)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     misc_feature    2969..2971
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3185..3199)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    complement(3186..3198)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            3211..4131
                     /locus_tag="BV401_RS28605"
                     /old_locus_tag="BV401_28670"
     CDS             3211..4131
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="BV401_RS28605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28670"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_079258847.1"
                     /transl_table=11
                     /translation="MSGERTITSRNFDVNQLRTLNTIVETGSFRRAADALALTQPAVSY
                     HIRRLEAVLHGPVFVRTRGRLELSDAGEELLFYARKILTVNDEAMARLTGPKDGLRLTI
                     GVSEQLEDLLEDLLVGLTRALPRVTLTARIGASEHLTTRTAEQEAGAAVVIGRARGERS
                     RSLGCLQLAWYAQDTASLAAGRSIPMVLPAEPCNTRTHIISALDAQGVSWHVAYEGPDL
                     AGLRAATRAGLGVIGLLADCGEKWNLTPVPGGTLPFHPGFVPVSFVHAPGTPADVVEAA
                     FSVAQAALRQVPLAEEPGRITGSAA"
     misc_feature    3237..3254
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.98"
                     /tool="antismash"
     gene            complement(4249..4935)
                     /locus_tag="BV401_RS28610"
                     /old_locus_tag="BV401_28675"
     CDS             complement(4249..4935)
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058851.1"
                     /locus_tag="BV401_RS28610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28675"
                     /product="M24 family metallopeptidase"
                     /protein_id="WP_079258848.1"
                     /transl_table=11
                     /translation="MDEEQRAALLLEAQDKAEELFDELERRQLIVAGKRERELSDEIRD
                     LAHEMFGIERFWHKRIVRAGPNTLHPYRANPPDRVIAADDVLFCDFGPLLEQWEADVGR
                     TFVLGDDPVKHRLRDDVSVVFDAGRRYFHEHPDITGAQLFAEVRRLAAGAGWEIGATHA
                     GHLVGEFPHERINGDDIEYYITTGSDEPMRRPDRAGRLCHWILEIHLVDRARGFGGFHE
                     QLLDLG"
     gene            complement(4941..7082)
                     /locus_tag="BV401_RS28615"
                     /old_locus_tag="BV401_28680"
     CDS             complement(4941..7082)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019044745.1"
                     /locus_tag="BV401_RS28615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28680"
                     /product="molybdopterin oxidoreductase family protein"
                     /protein_id="WP_237287885.1"
                     /transl_table=11
                     /translation="MNLDTGDAARGALAVSAPAVSVPAGRALKILPGGCPLDCPDACSW
                     QVEVEDGVAVRLRGTPDHPYTRGTLCVKVNQYLEHTRAPDRLTHPLRRTGRKGEGRFER
                     IGWDEALDEIAGRLTDVIDHYGGQAIWPYQGTGNLGYLQGLQGRAGSRLWNTLGASRHD
                     MTICSVAGLVGTGYTLGTSRGIDPEDLRHSRLILLWGCNTLTTSHHLWKVLSQAQRAGA
                     YVVAIDPVLTKTARLADEHVPLNPGTDAALALGLLNVVVSLGAEDRAYLAEHTEGWPEF
                     RARIEQFTPERTAEICGLPVETVERLGRRLAVTRPTGMKAAQGIQRHAGGGMALRTLAA
                     LPGVTGDWKLPGGGLAYSTDGYFGGDREALFRDDLLSEPVRSLSMTRLGEALTTVDDPP
                     VKALFVYGANPATAVGGQGQIHQGLLRADLFTVVMDHFRTDTVDYADLVLPATMQTEHT
                     DLLDGYGHMYITWNEPAVAPPGECLSTTETFRRLAARLGLKDPSLFDSDEDLARQLLSG
                     GHPSLDGVDLDRLRREGYVRLNYPSPLVPFADGFPTPSGKLEFVSATAAADGYDPLTGY
                     TPPKEAADPELARRLPLVLISSASHFFLNTTFGNKESLVRRAGAPFVELHPDDAAARGL
                     TEGQQVRIFNDRGAFTAQLRVSDAVRPGVARTAKGWWSKLTGHAAGVNATVAERDSDMG
                     GGAVYHDNRVEVSAAERQG"
     gene            complement(7079..7957)
                     /gene="dapF"
                     /locus_tag="BV401_RS28620"
                     /old_locus_tag="BV401_28685"
     CDS             complement(7079..7957)
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapF"
                     /inference="COORDINATES: protein motif:HMM:TIGR00652.1"
                     /locus_tag="BV401_RS28620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28685"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_158525930.1"
                     /transl_table=11
                     /translation="MTTLLKYHTLGNDYLVADPELGAPSPGATATRVLCDRRTGIGADG
                     VLYGPLPATRPTAGPADTFDVRVFNADGSECARNANGLRLFARYLREHGRTTQDEITLR
                     TPGGAVNVRLGRPVTAPGTIDLGSWTHHSPALADGEELVGASLRLGPDTGLHVTAVHNG
                     VPHLVSLVDDATPELAARIGPEIVAYPGFTERPNAELLTVEDRRTLRLQIWERGVGYAP
                     ASGSGACAAACAAYRLGLTDPSVTVVMPGGTVAVEITRDERVLLSGSSSYVGQIALAEE
                     FVPHLRAELPR"
     gene            complement(7957..8643)
                     /locus_tag="BV401_RS28625"
                     /old_locus_tag="BV401_28690"
     CDS             complement(7957..8643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933747.1"
                     /locus_tag="BV401_RS28625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28690"
                     /product="2OG-Fe dioxygenase family protein"
                     /protein_id="WP_079258850.1"
                     /transl_table=11
                     /translation="MTLNAQHFKIFDLPKTGDDILKSFDDLAFDEYIGNGNRWRRFSQY
                     RLEHRDGAWDFERLPHRPYVTYSKFNPIAGGIRRHYQPIQIDLVEHIREACAQIPLPEN
                     DIWQINVHQYRVIANKELQGVVVPEGVHQDGHEFVVISVYNRVGVTGAELTLRGAEDKE
                     TPIFTATLPAGQAIAFDDRALWHYVTDIVPVEEEGHRDITVVSFSRWSERWYGDTFEEE
                     AIGEGR"
     gene            complement(8679..9731)
                     /locus_tag="BV401_RS28630"
                     /old_locus_tag="BV401_28695"
     CDS             complement(8679..9731)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025871.4"
                     /locus_tag="BV401_RS28630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28695"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_158525931.1"
                     /transl_table=11
                     /translation="MPAPQQNHFPLLAGFTAALTSSAYAKWQQLVDDYAHRAELAGECR
                     RLADLAFTGRDAAARAHLHEVLAVVYAHEFSQSAARNPDQDSQPVLCDVTSILENAMLE
                     HEFGQIPEELLSGYPTGGKEYVRWLKALIQDHPASTHPMYAEHLPTVATAEDIRFLLAQ
                     ETSLDPRFDDILAVMQLGATGAEKMEIAANYWDEMGNGEFADVHTTLFSQCLTSIGVDQ
                     DYVEQNLLPIAKECGNISAGLALSRRHYLRAIGYYGVTEFLAPRRFRQLVTAWDRLGLP
                     PEGKIYHDIHINIDAHHAAGWYKNVIGPVVERDPAAGREVALGTFVRLNTSAQYLDRVL
                     EVCLKQPQPA"
     misc_feature    complement(9906..9919)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.39"
                     /tool="antismash"
     gene            complement(10001..11692)
                     /locus_tag="BV401_RS28635"
                     /old_locus_tag="BV401_28700"
     CDS             complement(10001..11692)
                     /EC_number="2.3.3.13"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980755.1"
                     /locus_tag="BV401_RS28635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28700"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_079258852.1"
                     /sec_met_domain="HMGL-like (E-value: 9.6e-73, bitscore:
                     243.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEFATRPVWNEQRPSPMPVHRYRSYAEEVEPVLLPDRTWPDRT
                     ITRAPLWCSVDLRDGNQALAVPMSPARKHQFFQLLVGMGYKEIEVGFPAASATDLAFVR
                     EIIESDTVPDDVRLQVLSPCRPELIDRTVEAVAGARKVTLHIYNPTSELQRRVVFRQER
                     TQIRELAVASARRLAEAAESLTGADVRLQYSPESFTGTELGFAAEVCNAVLDVWQPTPQ
                     RPAAICLPATVEMTTPNTYADSIEWMSRNLERRDSVLLSLHPHNDRGTAVAAAELGLAA
                     GADRIEGCLFGNGERTGNVCLVTLGMNMFSRGVDPEIDFSDLGEVRRVVEECTELPVHE
                     RHPWGGELVFTAFSGGHQDAISKGISALADESHSSGSDLRDEHWQVPYLPIDPSDVGRE
                     YEPVVRVNSQSGKGGVAFVLNDSYGLRLPQQLRADFAVLVQQVTDREGGELSPKRLREL
                     FHTAYTSPPGVLRLLDRTPSSVTVCLDGIDKEIPLNGPASLPAFADALTQLGLDLTLTS
                     ATAHELPEGGAIAYLSSGASWAVGTGEDTVSAELDAAVGIINRTHH"
     misc_feature    11702..11718
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     misc_feature    11743..11757
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.95"
                     /tool="antismash"
     gene            11889..12575
                     /locus_tag="BV401_RS28640"
                     /old_locus_tag="BV401_28705"
     CDS             11889..12575
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-147). E-value: 4.8e-09. Score:
                     26.7. Matches aSDomain: nrpspksdomains_BV401_RS28640_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.4"
                     /locus_tag="BV401_RS28640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28705"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_079258853.1"
                     /transl_table=11
                     /translation="MAPTFEIKGNDLWDPTTFDALRRQLIPSFDLIYEAAVRTVAATVP
                     AAPRVLDLGAGTGLLSAAILRDLPEANVVLVDRSELMLTQARGRFASQERVTVQTGDLT
                     DPLPEGQFDAVVSGLAIHHLSHTDKRDLFRRIREALRPGGVFVNVEQVQGPLPHLESLY
                     DSQHELHVVREQAPPEEWAAGRERMKFDVCTDLETQLQWLRDAGFRSVDCLAKDFRFAT
                     YAGWVS"
     aSDomain        12033..12329
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS28640_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.80E-09"
                     /label="BV401_RS28640_oMT.1"
                     /locus_tag="BV401_RS28640"
                     /protein_end="147"
                     /protein_start="48"
                     /score="26.7"
                     /tool="antismash"
                     /translation="RVLDLGAGTGLLSAAILRDLPEANVVLVDRSELMLTQARGRFASQ
                     ERVTVQTGDLTDPLPEGQFDAVVSGLAIHHLSHTDKRDLFRRIREALRPGGVFV"
     gene            12575..14071
                     /locus_tag="BV401_RS28645"
                     /old_locus_tag="BV401_28710"
     CDS             12575..14071
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (8-396). E-value: 1.6e-52.
                     Score: 170.4. Matches aSDomain:
                     nrpspksdomains_BV401_RS28645_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="BV401_RS28645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28710"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_079258854.1"
                     /sec_met_domain="AMP-binding (E-value: 3.6e-40, bitscore:
                     136.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALYQAVREVARRRPDAIAVETTAGERTSYAELLAAADRVAAGL
                     RAHGVAEGRVVVCSGLANDASYMAFLLGVCVAGAAYVPLLADFDAAAVARAVRLTRPVL
                     WVGPENHHRAGVTVPRVELAELSAPGAPATPGIADADVAPPDRAFAPGTFRMLWTSGST
                     KAPKLVTWRQEPFVRERRRWIASIEATEHDAFFCQHTLDVAHATDLHAFAALLAGARLV
                     LADPGAEPATLLAQLAASGATYTSMLPNHYEDLIAAAGQRPGTDLSRLRRPMCGGAYAG
                     PALIASAAEVLGIHIRHIYGSTEFGLALGNMADEVQTLGGMHEVAGVRARLEPLAGYDW
                     DDLGTLVLTSDCTSDGYVDDDEANAATFRGSDFWTGDVAQRLDGGGFRLLGRVTDLLLA
                     TDGPLAAPFLDELIARDCPVAESVSLTADTDSLTNRVLVVLRAAPGTSDDDAVGAVDKL
                     LASHGLTGPVLAFERIPRTVVGKADRALLRSRYLAASSSS"
     aSDomain        12599..13762
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS28645_AMP-binding.1"
                     /evalue="1.60E-52"
                     /label="BV401_RS28645_AMP-binding.1"
                     /locus_tag="BV401_RS28645"
                     /protein_end="396"
                     /protein_start="8"
                     /score="170.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="REVARRRPDAIAVETTAGERTSYAELLAAADRVAAGLRAHGVAEG
                     RVVVCSGLANDASYMAFLLGVCVAGAAYVPLLADFDAAAVARAVRLTRPVLWVGPENHH
                     RAGVTVPRVELAELSAPGAPATPGIADADVAPPDRAFAPGTFRMLWTSGSTKAPKLVTW
                     RQEPFVRERRRWIASIEATEHDAFFCQHTLDVAHATDLHAFAALLAGARLVLADPGAEP
                     ATLLAQLAASGATYTSMLPNHYEDLIAAAGQRPGTDLSRLRRPMCGGAYAGPALIASAA
                     EVLGIHIRHIYGSTEFGLALGNMADEVQTLGGMHEVAGVRARLEPLAGYDWDDLGTLVL
                     TSDCTSDGYVDDDEANAATFRGSDFWTGDVAQRLDGGGFRLLGRVTDL"
     gene            14110..15501
                     /gene="leuC"
                     /locus_tag="BV401_RS28650"
                     /old_locus_tag="BV401_28715"
     CDS             14110..15501
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961985.1"
                     /locus_tag="BV401_RS28650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28715"
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="WP_079258855.1"
                     /transl_table=11
                     /translation="MTRKTLVDKIWDLHVVEPGASDLLYIDLHLLHEVSSPQAFAGLRE
                     AGRTVRRPALAVATTDHDVPTDGRELSPDAGAAKQVRVLADNCRDNEIELHPVGSPGQG
                     IVHVIGPQMGLTRPGTTIVCGDSHTATHGAFGAIAFGIGTSEIEHVLATQTLRARRPES
                     MAVTVTGDLLPGATAKDLALGILAAGGTDAGTGTLIEFRGPAVRALSMEGRMTLCNMAV
                     EMGARSGLVAPDETTFAYLKDRPRAPRGDLWDQAIAEWRTLRSGPDAVFARELVVDAGS
                     IVPRVTWGTNPGQSVPVDGAVPHPADSADPGERAAAERALTYMGLRPGTPMRDVGIDVV
                     FIGSCTNSRIEDLRAAADVLRGRRVADGVRGLVVPGSMLVRDQAEREGLDRVFTAAGFE
                     WRMPGCSMCVGINGDTVAPGQRCASTSNRNFEGRQGVGARTHLVSPATAAATAVAGRFA
                     TPADL"
     gene            15512..16108
                     /gene="leuD"
                     /locus_tag="BV401_RS28655"
                     /old_locus_tag="BV401_28720"
     CDS             15512..16108
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435482.1"
                     /locus_tag="BV401_RS28655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28720"
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="WP_079258856.1"
                     /transl_table=11
                     /translation="MEPLVRVTGRGVPLDRPNVDTDQIIPAAWLKNTTRTGYADGLFEQ
                     WRLDPDFVLNRPERVGASVLVSGPNFGCGSSREHAPWALHEWGFRAVIAPGFADIFRNN
                     MPNAGLVPVWCEPDVVAALMAATTTCATAEICVDVAARIVTCEAAGVGAAPFRLDDDAR
                     DRLVAGLTQLEVTLRAADRIAAFERARAPWLHISA"
     misc_feature    complement(15513..15527)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.13"
                     /tool="antismash"
     gene            <16220..16450
                     /locus_tag="BV401_RS28660"
                     /old_locus_tag="BV401_28725"
                     /pseudo=""
     CDS             <16220..16450
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_053126455.1"
                     /locus_tag="BV401_RS28660"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28725"
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="PGGGNRQLKRAMFPSALAALHEPASHTYYDRCRARGKTHAQSLLR
                     PVRHRIGVPLAMLRDGTFYEPRNSRTARRRT"
     gene            complement(16660..>16865)
                     /locus_tag="BV401_RS28665"
                     /old_locus_tag="BV401_28730"
                     /pseudo=""
     CDS             complement(16660..>16865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104787.1"
                     /locus_tag="BV401_RS28665"
                     /note="catalyzes the formation of phenylpyruvate from
                     prephenate in phenylalanine biosynthesis; frameshifted;
                     incomplete; partial in the middle of a contig; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28730"
                     /product="prephenate dehydratase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GFAAGGVNLTKIESYRCAQVSTPSASISRSRGTPMTPASTWPCTG
                     CGSSPRRCAS"
     gene            <16925..>17110
                     /locus_tag="BV401_RS28670"
                     /old_locus_tag="BV401_28735"
                     /pseudo=""
     CDS             16925..>17110
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134987.1"
                     /locus_tag="BV401_RS28670"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="BV401_28735"
                     /product="glycerol-3-phosphate acyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRTTEIIREMTGAPGERVAVLSGPNLAREIMAEQPAAATIACPD
                     EEAARRFQTACHTPYFR"
     gene            17121..>17881
                     /locus_tag="BV401_RS28675"
                     /pseudo=""
     CDS             17121..>17881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676472.1"
                     /locus_tag="BV401_RS28675"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKPGGLDPPVRVGDNGRTVVSQAGAVLLWRQSARAAWMLRCRRR
                     WRRGARRGGARPRQDPAGPCAGDHPGRGLPGRCRDTEGRTSPLRAGGLRPDRLPPHRRA
                     RRSGLPGTGRHPHRTGRSPRTHLAADRDRRPARRRAGDRGHRRRAGTGPLRQGGRHTDL
                     EEDLWASSAHGLRRPRARRHLRAGRGAAAARQGGPPALPTCLSTTPRRTRSGWRSSRSP
                     STCWPGCRCWP"
     misc_feature    17721..17723
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18215..19384)
                     /locus_tag="BV401_RS28680"
                     /old_locus_tag="BV401_28750"
     CDS             complement(18215..19384)
                     /NRPS_PKS="Domain: AMP-binding (50-215). E-value: 3.4e-13.
                     Score: 40.8. Matches aSDomain:
                     nrpspksdomains_BV401_RS28680_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="BV401_RS28680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28750"
                     /product="AMP-binding protein"
                     /protein_id="WP_079258857.1"
                     /sec_met_domain="AMP-binding (E-value: 6.4e-10, bitscore:
                     37.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGSIDPETLLAHARTIAASGGKPVPDGAKVLSDLEICGPAEITA
                     ITRAAAERDGSVLVSSGGTTGTPKLTYLPHHMAFDRLLSVWRPLGVGDVVLNLYDAGRM
                     WGTHYFVQKIAECTESTVIPSGPMTTEELELRLPMLREVGVSALASVPSVLADFAETVL
                     KTGVKPPVKTIIWMGEAWTDAKRELVRQAFPDVQLWGIYGSVETWAMGSNRPGCDETTL
                     HLLEDQIFELEDAGALLTRAGDGWTVPVVRYRLGDRIEAAECRCGRGDAFRVLGRADDG
                     FGLLGNFVNIADIVDRARQCPDVVDAQIVLVRDTDLADSARSMTVEYTGTAAPETVRNW
                     LTGGHVRLGTVDSQHPEAISACRVERLRRITRTNKTPAAVWQDALGSSA"
     aSDomain        complement(18740..19234)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS28680_AMP-binding.1"
                     /evalue="3.40E-13"
                     /label="BV401_RS28680_AMP-binding.1"
                     /locus_tag="BV401_RS28680"
                     /protein_end="215"
                     /protein_start="50"
                     /score="40.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AERDGSVLVSSGGTTGTPKLTYLPHHMAFDRLLSVWRPLGVGDVV
                     LNLYDAGRMWGTHYFVQKIAECTESTVIPSGPMTTEELELRLPMLREVGVSALASVPSV
                     LADFAETVLKTGVKPPVKTIIWMGEAWTDAKRELVRQAFPDVQLWGIYGSVETWAMGSN
                     RP"
     misc_feature    complement(19379..19394)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.33"
                     /tool="antismash"
     misc_feature    19454..19468
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.44"
                     /tool="antismash"
     misc_feature    complement(19526..19539)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.7"
                     /tool="antismash"
     misc_feature    19527..19540
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.03"
                     /tool="antismash"
     misc_feature    complement(19527..19542)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.01"
                     /tool="antismash"
     misc_feature    19532..19541
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.75"
                     /tool="antismash"
     gene            19610..20872
                     /locus_tag="BV401_RS28685"
                     /old_locus_tag="BV401_28755"
     CDS             19610..20872
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024925.4"
                     /locus_tag="BV401_RS28685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28755"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_079258858.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2e-06, bitscore:
                     26.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKTVVLVGVPWNVHELDDAVRDAATLGASLLLVDTPESLAQIG
                     EQTAVETRSVKALDPLLIADCVRDAEPATVLAITEFCMELAAAVRERLGIAGTPPTVEA
                     RVLDKAATREVLREHGLTQVGFHRTSLLSTDDLLGGLEPPVVVKPRAFSGSHGVTFVTD
                     RSELARVFEPYDLAEANHVDRDTRVAHLTGDHRTHEVIVEEYVPGPEISAEGLVVDGRL
                     TLFTLTDKVNTGMPHFEEIGHVVPSRYTEERKAQVEEYLQAVVSALGFVTSPMHAEIKL
                     LDDRIELVEIHTRYPGDRVVELLESAYEIRPYEAYFDAMVNGRAPVPPRPTGVYHGVGF
                     FNCSTTAPFTWPSYAFPHPEAVVSVDLDRRRAPRVFAYEGLRIRYWRAGHVLFASEDHA
                     SVHANIGFLFDNTPRQGGSGS"
     gene            complement(20984..21223)
                     /locus_tag="BV401_RS45030"
     CDS             complement(20984..21223)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS45030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237287888.1"
                     /transl_table=11
                     /translation="MRFWLSNLPDDAPLRTLVRPATLRRRIEHDCREMKQVGPAHFEGH
                     TWNGWHHHVTLVSAAHAFCTLQRMVRTPKETAPV"
     gene            complement(21427..21975)
                     /locus_tag="BV401_RS45035"
     CDS             complement(21427..21975)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.4"
                     /locus_tag="BV401_RS45035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_250644891.1"
                     /transl_table=11
                     /translation="MVPAINPTALIIDDTGLLKDGDASVCVSRQYTGTAGKVTNCQAGV
                     SLHLASDTASAAIDWRLFLPRSWDPASPQADLAKVARRERCGIPPDVGHVEKWQLALDM
                     TDESRFWSVDAPLVVADGGYGDTAAFRLGLEERGLHYVVGTSTTVTAHTHDATPCPSSH
                     SGRGRPPQPAYPQAPRSFK"
     misc_feature    complement(22221..22236)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            complement(22436..23842)
                     /locus_tag="BV401_RS28695"
                     /old_locus_tag="BV401_28765"
     CDS             complement(22436..23842)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00711.1"
                     /locus_tag="BV401_RS28695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28765"
                     /product="MFS transporter"
                     /protein_id="WP_079258859.1"
                     /transl_table=11
                     /translation="MTRLRANPWATLVVLSLGYFMTLLDSTIVTIAIPSIIDSMHATLP
                     QVLWALNSYIIAITVLLITAGRLGDRYGPRQVFVAGVLLFTVASLLCGLATVPGVLVAA
                     RVLQGAGAALLMPQSVTLIVASFPRERRGTALGVWGAIGGVASVLGPSLGGLLINLAGW
                     RWIFLINLPIGVLVVAAGLTVVPDLRTDRRHSLDLPGVVIASLALACFAYAVTNGADHH
                     WGPLIWALLAAAALFGVGFTARQRQRQNDDPLVPFALLRIRGYTVTLGIAAAITGATFG
                     ITVVAALYFQSVVGLSAFRAGVVLAPASAMSVLVALVAGRLADRVEGRFILLTGMVVQG
                     AGILWTALLMTGSAHGEDFLAPMTVIGMGNGCSIAPRTTVAMRDVPQELTGAASGILET
                     MRQVGAMVFTAGVVALAQGLESVAGGSSTAMRAATFLPVAALALGALACLALPRERPDP
                     AVHTRPLPSE"
     gene            complement(23839..24636)
                     /locus_tag="BV401_RS28700"
                     /old_locus_tag="BV401_28770"
     CDS             complement(23839..24636)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (10-248). E-value:
                     1.9e-33. Score: 108.0. Matches aSDomain:
                     nrpspksdomains_BV401_RS28700_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="BV401_RS28700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28770"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_237288324.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-26, bitscore: 92.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.7e-20, bitscore:
                     71.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHVRRPGAGPIVLFVPGLGMTSQSFAHTTAGLGPGYDVVTVDLR
                     GHGSSPTPPPGWTLDDAAADLAQVIDRLDLHDVTLVGWSLGATVTYNYLERYGTDRVSR
                     LVSVEMSPYLLREEGWEHAAFGGLDAFGALHATQQQWADPDRYLTALVENCFAAGADPE
                     PALTQLLLADSLKTSRLALLALWSGVLTQDWRERIGALTLPTLLVHGAKSRIFPTEVGK
                     WLLGALPDARLEMFSESGHALFLEEPGRFVRVLRDFVDGTAGA"
     aSDomain        complement(23893..24606)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS28700_Abhydrolase_1.1"
                     /evalue="1.90E-33"
                     /label="BV401_RS28700_Abhydrolase_1.1"
                     /locus_tag="BV401_RS28700"
                     /protein_end="248"
                     /protein_start="10"
                     /score="108.0"
                     /tool="antismash"
                     /translation="PIVLFVPGLGMTSQSFAHTTAGLGPGYDVVTVDLRGHGSSPTPPP
                     GWTLDDAAADLAQVIDRLDLHDVTLVGWSLGATVTYNYLERYGTDRVSRLVSVEMSPYL
                     LREEGWEHAAFGGLDAFGALHATQQQWADPDRYLTALVENCFAAGADPEPALTQLLLAD
                     SLKTSRLALLALWSGVLTQDWRERIGALTLPTLLVHGAKSRIFPTEVGKWLLGALPDAR
                     LEMFSESGHALFLEEP"
     CDS_motif       complement(24364..24405)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS28700_0001"
                     /evalue="2.40E-04"
                     /label="NRPS-te1"
                     /locus_tag="BV401_RS28700"
                     /protein_end="91"
                     /protein_start="77"
                     /score="13.7"
                     /tool="antismash"
                     /translation="VTLVGWSLGATVTY"
     misc_feature    complement(24684..24693)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    24767..24781
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.79"
                     /tool="antismash"
     gene            25212..25751
                     /locus_tag="BV401_RS28705"
                     /old_locus_tag="BV401_28775"
     CDS             25212..25751
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677105.1"
                     /locus_tag="BV401_RS28705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28775"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_079258861.1"
                     /transl_table=11
                     /translation="MRYPQGGGLTTERRVFREHIRMRAAELFALGHDNATIAKQLRVSV
                     RSVQRWHRAWEHGGTTALESKGPASHPKLSEALFEVLEQELAKGPVAHGWPDQTWTLAR
                     IKTLIGRRFHKSMTLSAIAQMLHRHGFSHQVPARRATERGEEAVTGWVKETGPQAETPW
                     RRSGPGCASRTKPASR"
     misc_feature    25290..25292
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            25804..26295
                     /locus_tag="BV401_RS28710"
                     /old_locus_tag="BV401_28780"
     CDS             25804..26295
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669009.1"
                     /locus_tag="BV401_RS28710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28780"
                     /product="transposase"
                     /protein_id="WP_237287889.1"
                     /transl_table=11
                     /translation="MRGRSQRRFSIAALTCYKQGERSRLIYRPKRHADHKRGGRRSFTW
                     TDYRDLLIAAHQQLGAPIVLVWDNLNVHRDRRLRKFIDTHDWITCYFLPSYAPDLNPVE
                     GVWSLLRRSSQVNTAFTDPDHLMCALRHGLRQIQYRSDLVDGCLAGTGLTLTTSRQQGQ
                     "
     gene            26478..26603
                     /locus_tag="BV401_RS45570"
     CDS             26478..26603
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS45570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_257788926.1"
                     /transl_table=11
                     /translation="MTYDAKMQCEAEELPYAQQNGYDEVWCDGPGGRAEYTVWVR"
     gene            complement(26934..27557)
                     /locus_tag="BV401_RS28720"
                     /old_locus_tag="BV401_28790"
     CDS             complement(26934..27557)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356868.1"
                     /locus_tag="BV401_RS28720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28790"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_079260645.1"
                     /transl_table=11
                     /translation="MSDQRRHRLRLDVSREASRLFWAQGVDATSGDQIAEAVGLSTRTI
                     WRHFRSKESCAEPIVMRGVEWEMSTLRSWPPQLSLEVHFAAESSKFGREASDVERMDTE
                     LAIKMIRLADTEPAIRTAWLMACDQVEREMAEIIAERLGLPAEDLDVRLHAAAASAALR
                     VLNEHIGAAILEGTDPRDFADAPARIARAVRTATGGAVGDPVTT"
     misc_feature    complement(27648..27663)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.16"
                     /tool="antismash"
     gene            <28133..28285
                     /locus_tag="BV401_RS41855"
                     /old_locus_tag="BV401_28795"
                     /pseudo=""
     CDS             <28133..28285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612292.1"
                     /locus_tag="BV401_RS41855"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_28795"
                     /product="IS982 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GQLDLEQHGERTFEGVAVRVAQRILAMAAAIWRNHRTGAPSTRSL
                     AAFDH"
     misc_feature    complement(28158..28173)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.43"
                     /tool="antismash"
     misc_feature    complement(28346..28359)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.08"
                     /tool="antismash"
ORIGIN
        1 cgcaccggag gacccgtacc gggtggctcc ggcggagcgt ccgtacgccg acgccgtcgt
       61 cgacggcccg cgcccgctgc ggatcgggct gaccacggtg tcctcgctcg gcggaccggt
      121 tgatccgcag gccgccaccg cggttcggga cgcggcggag ctgctcaccg cactcggaca
      181 cgtcgtggag gagtccgccc cggccatcga cgggcagcgc ctggcgaccg acttcctcac
      241 gacctggtac gcgatggtcg ccgccgaggt cgccgccgca cgggagttca ccggctgtgc
      301 cgaggacgac ttcgagatcg agacccggat catggctgcg atcggccgga gccttccggc
      361 gccgagatat ctggccacgc agtcccgctg gcatcagcac acccgggcgc tggccgcgtt
      421 ccacgagcgc tacgacatgc tgctcacccc gaccacggcc cggccggcgt ggctcatcgg
      481 cgagttcgat ctcgccttgc cggtccggct cgccgcacgg gggctgctgg ctgcccggat
      541 cggcggtgtg ctgggccgga tgaacctcgt cgagaaactg gccgtcgcca accttgagcc
      601 agcgcccttc acccagctgg cgaacgtgac cgggcgcccg gcgtcgtcgg tgccgctgta
      661 ccggacgtcg agtgggttgc cgctcggcgt ccagttcgtc gggcgcccgg gttcggagcc
      721 cgagctgctg gcactggccg cgcagctgga gcgagcgcgg ccgtgggcgc acctctggcc
      781 gtcgttgccc gatacgccct ccacggcctg acacctttga ggacaattac acgtatgact
      841 actgtattct cacgcattat cgctggcgag ctgcccggtc acttcgtctg gcaggatccg
      901 gaaatcgtcg cttttctgtc catcgctccg ttgcggcctg gccacaccct cgtggtgccg
      961 cgacgtgagg tcgaccggtg gacggacgtc gacggggccc tcctggcgcg ttgcttcgag
     1021 gtagcccagg ccgtggggca aggggtgcgg cgggcttggg acgctccgcg cgccggcctc
     1081 gtcatcgcag gcttcgaggt accgcatctg catatacatg tcgcgcctgt ctgggacatg
     1141 tccgactttg atttcagcaa agccaagcag gaggaggatc agtcggcttt ggctgaagca
     1201 gcagcaaagc tccgtgccgc cctgctggaa ctcggttatg aacaggcacg ggactttggc
     1261 cccggggtgt gaacgatgcc gaccgtgagg gccagacgaa ggtcttgact gtgccgtagc
     1321 ggcacagtgt tggctgagaa ccatgagctg gagtactcgg gagatcgccg agcttgccgg
     1381 caccagcctc cgggcggtgc ggcactacca cgaggttggg ctgctggagg agcccgagcg
     1441 ccgtgtcaac ggctacaagc agtacggcgt gccgcacctg gtccgcctgc tgcggatcaa
     1501 gcggcttgtc gatctagggt tctcgctgaa ccagatcgcg gagacggtgg acgagggcga
     1561 gcaccccggg cgggccctgc gcacgctcga cgcggagctg gccgcgaccg tcgagcggct
     1621 gcagcgggcc cggctcgaac tcacgacact catcgagcag cgcgccccgg ccgacctgcc
     1681 tgcggaactc acacccggcg aagcaacggt gctgtccaaa accgaccgct cgctccttct
     1741 ggtcatggcc cggttgatga acggggagca actgcagacc tacggtgcgc tggtgcgcaa
     1801 tctgcctgct cacccggtca atcaggagtt cgatgaactg tccgctgacg caggcgagca
     1861 catccgccaa gacctcgttg agcggatggt gccctacctg cgctggctgc ggcaggacca
     1921 tccggacctg cccgacctgt acacggccgt ctcgaagggg aagaaaatca ttcgagagac
     1981 catggagacg gtcctgcatg agctgtacaa cccggcgcag ctcgatgtct tgcaccgggc
     2041 ccacgtgata gtggacgggt ccacccagcc ccgaccgggg cggaacgcta ccgaacttcg
     2101 ttgaccgcgc cggtctcccg ctccatgccg tcgccgtcga cggccgcacc cgtgagcgac
     2161 acgccggagt gaccatgcag tcccatgccc atgcagatgc ccgctacgca gtcagcactg
     2221 ccttgctggc cgagctgcgg tccagaatcc ctgcgggccg cgtgctcacc aacggaccgg
     2281 agtacgcgaa agcagtggcg ttgttcaacg cagcggtcga tttccgtcct cttgtcgtcg
     2341 tgcggtgcgt gaccaccact gacgtgcagg ccggggtacg cgccgctcga tcgaccgtag
     2401 cgcttttcgt ggtaccggga ccggcccgga ccggcggaaa ctgtggaatt cgtcctcgcg
     2461 gtcgtgcggg taggcggtgt ccggccacgg tagttggtgt tgcagaactg gaaggacgga
     2521 acgatcgacc tcgacatggc cggctggccc attccgatca gatcacccac cgcagcctcg
     2581 ttcgaaatcg ccgcgccaga agacacctct cgacatcgtt gtccgcttct cgggacgccg
     2641 agaaagtggt cgccgtcgag gcgggcgagg ccatcacccc cggttcccct ccgtgctgag
     2701 gaagttcccc gatggacagg gcctggtgcc aatcaccatt cgaccagatg acaatctcag
     2761 gttggttcga gtcatgtgca acaactgtgg ccgtataaat caaagtgcca tcgcatcacc
     2821 cccgtacatt ccgagtgaga cggccgagga ccgccacgaa agactgatcg ccctgctggc
     2881 cacgggtcat accgacgcca gcgcggcccg gcaactcggc gtcagccgcc gcaccgtgac
     2941 ctacatgctc cgctccatga tggacggatt aggcatcaac aaccgcttcc agctcggcat
     3001 cgccgtcggc gcccacagtc gcgcctgcgc cgcctgtccg gcgccccgcg aacctgccat
     3061 gacgaacgcc gcacacaacg acggccgtta ctgaggactc gctcgaagag cgtcccgtcc
     3121 gtggatgtgc gcgaacccct ttttcgtgag actcagttcg gatatcgggg gatgttcgag
     3181 gcggtttgcc gaatgcgaaa gtgaagtccc atgagtggag aacgaaccat cacgtctcgt
     3241 aatttcgatg taaatcagtt gcgcacgctg aacacgatcg tggaaaccgg gagtttccgg
     3301 cgggcagcgg atgcgctcgc actgacccag cctgcggtaa gctatcacat tcgccgactc
     3361 gaggcggttc tgcacggccc ggtgttcgtt agaaccaggg gccggctgga actcagcgat
     3421 gccggtgagg aattgctttt ctacgcacgc aagattctca ccgtcaatga cgaggcgatg
     3481 gcccggctga cggggccgaa ggacgggctc cggctcacca taggtgtttc ggaacagctg
     3541 gaggacctcc tggaggatct gctcgtcggc ctcacccgtg cgctgccccg agtcacgctg
     3601 accgcgcgga tcggggcgag tgagcacctc accacgcgaa cagccgagca ggaggccggc
     3661 gccgccgtcg tcatcggccg tgcccgcggc gagcgcagcc gctcgctcgg ctgcttgcag
     3721 ttggcctggt acgcacagga caccgcgagc cttgccgccg gacgctccat tcccatggtg
     3781 ctgcccgccg agccgtgcaa cacgcgcacc cacatcatca gcgccctcga cgctcaggga
     3841 gtctcctggc acgtcgccta cgagggcccc gacctggccg ggctgcgcgc ggccactcgg
     3901 gcggggctcg gcgtcatcgg acttctcgcc gactgcggcg agaagtggaa cctgacgccg
     3961 gtccccggcg gcacgctgcc cttccatccc gggttcgtgc ccgtctcctt cgtccacgcg
     4021 ccgggcacgc cggctgacgt ggtcgaggcg gcgttctccg tggcccaggc ggcgctccgg
     4081 caggtgccgt tggccgagga gcccggacgg atcaccggga gcgccgcctg acgggcccac
     4141 cccgacgtcc ctgtctccgg ccgccgtgct ccccgtggcg ggccggagac agggacgacg
     4201 gccgcggggt ccgcggggcc gggccggcct cacgcgcggc ggatgccgtc agccgaggtc
     4261 cagcagctgc tcgtggaagc cgccgaaacc ccgggcccgg tcgaccaggt ggatctccag
     4321 gatccagtgg cagaggcggc cggcccggtc cgggcggcgc atcggctcgt cgctgccggt
     4381 ggtgatgtag tactcgatgt cgtcgccgtt gatgcgttcg tgcgggaact cccccaccag
     4441 atgaccggcg tgggtggcgc cgatctccca gcccgcaccg gcggccagcc gccggacctc
     4501 ggcgaacagc tgcgcgccgg tgatgtccgg atgttcgtgg aagtagcggc gccccgcgtc
     4561 gaagacgacc gacacgtcgt cgcgcagccg atgcttgacc gggtcgtcac cgagcacgaa
     4621 ggtgcggccc acgtcggcct cccactgttc gaggaggggc ccgaagtcgc agaagaggac
     4681 gtcgtcggcg gcgatcacgc ggtccggcgg gttcgcgcgg taggggtgta gggtgttggg
     4741 gcctgcgcgc acgatccgtt tgtgccagaa gcgctcgatg ccgaacatct cgtgcgccag
     4801 gtccctgatc tcgtcgctga gttcgcgttc ccgtttcccg gcgacgatca gctgccgccg
     4861 ctcgagctcg tcgaacagtt cctccgcctt gtcctgcgct tccagcagaa gcgccgcgcg
     4921 ttgttcctcg tccatgcctc tcatccctgc cgctccgccg cggacacctc gacccggttg
     4981 tcgtggtaga cggcgccgcc gcccatgtcc gagtcccgtt cggccacggt ggcgttgacc
     5041 cccgccgcgt gcccggtgag cttcgaccac cagcccttgg cggtgcgggc caccccgggc
     5101 cgcaccgcgt cgctcacccg gagctgcgcg gtgaaggcgc cgcggtcgtt gaagattcgc
     5161 acctgctgtc cctcggtcag tccccgggcc gccgcgtcgt cgggatgcag ctccacgaag
     5221 ggcgccccgg cccggcgaac gagggactcc ttgttgccga acgtcgtgtt gaggaagaag
     5281 tgggaggccg aagagatgag aaccagcggc agccgacggg ccagctccgg gtccgcggcc
     5341 tccttggggg gcgtgtaacc ggtcagcggg tcgtagccgt cggccgccgc cgtcgccgac
     5401 acgaactcca gcttccccga cggcgtgggg aaaccgtccg cgaacgggac aagcgggctg
     5461 gggtagttga gccggacgta gccttcccgg cgcagccggt ccaggtcgac gccgtccagt
     5521 gacgggtggc cgccggacag cagttgcctg gcgaggtcct cgtcggagtc gaagaggctc
     5581 gggtccttca ggccgagccg tgcggcgagc cggcggaacg tctccgtggt cgacaggcac
     5641 tcgccgggcg gggcgaccgc gggctcgttc caggtgatgt acatgtgtcc gtacccgtcg
     5701 agcagatcgg tgtgctcggt ctgcatcgtg gccgggagca cgaggtcggc gtaatccacg
     5761 gtgtcggtgc ggaagtggtc catgaccacg gtgaacaggt cggcgcgcaa caggccctgg
     5821 tgtatctggc cctggccgcc caccgccgtg gcggggttgg cgccgtagac gaacagcgcc
     5881 ttgaccggcg ggtcgtcgac ggtggtcagg gcctcgccga ggcgggtcat ggagaggctg
     5941 cggaccggtt cggacagcag gtcgtcgcgg aagagggcct cgcggtcgcc gccgaagtag
     6001 ccgtccgtcg agtaggccag tccgccgccc gggagcttcc agtcccccgt caccccgggc
     6061 agggcggcca gtgtgcgcag ggccatgccg cccccggcgt gccgctggat gccctgtgcc
     6121 gccttcatcc cggtgggccg ggtgacggcc aggcgccgtc cgagccgctc gaccgtctcc
     6181 accggcagtc cgcagatctc cgccgtacgc tccggcgtga actgttcgat gcgggcgcgg
     6241 aactcgggcc agccctcggt gtgctccgcc aggtacgcgc ggtcctcggc accgagcgag
     6301 accaccacgt tgagcagtcc aagggctagc gcggcgtcgg tgccggggtt gagcggcacg
     6361 tgttcgtcgg cgagccgtgc cgtcttggtg aggaccgggt cgatggccac gacgtacgcc
     6421 ccggcgcgct gggcctgtga cagcaccttc cacaggtggt ggctcgtggt gagcgtgttg
     6481 cagccccaca gcaggatcag ccgtgagtgg cgcaggtcct cggggtcgat gccccggctg
     6541 gtgccgaggg tgtatccggt gccgaccagg ccggcgaccg agcaaatcgt catgtcgtgg
     6601 cgggaggcgc ccagggtgtt ccacagccgg ctgccggcgc ggccctggag gccctgcaga
     6661 tagcccaggt tgccggttcc ctggtagggc cagatcgcct ggccgccgta gtggtcgata
     6721 acgtccgtga ggcggccggc gatctcgtcg agcgcctcgt cccagccgat tcgttcgaac
     6781 cggccctcgc ccttgcggcc ggtccggcgc agcggatggg tgaggcggtc gggggcgcgg
     6841 gtgtgttcca ggtactggtt caccttcaca cagagggtcc cgcgggtgta ggggtggtcc
     6901 ggcgttccgc gcagccgtac cgcgacgccg tcctcgacct cgacctgcca ggagcaggcg
     6961 tccgggcagt ccagcgggca gcctccgggg aggatcttca gggcgcgtcc ggccgggacg
     7021 gagacggccg gtgcggagac agccagtgcc ccccgggcgg cgtcccccgt gtcgaggttc
     7081 accggggcag ctccgcccgc aggtgcggca cgaactcttc ggccagggcg atctgtccga
     7141 cgtacgagct ggatccggag agcagcaccc gctcgtcccg cgtgatctcc acggcgacgg
     7201 tgccgccggg catgacgacg gtcaccgagg gatcggtgag gcccagccgg tacgcggcgc
     7261 aggcggcggc gcatgctccg ctgccggagg ccggggcgta gccgacgccc cgctcccaga
     7321 tctgcaggcg cagggtgcgt cggtcctcga cggtgagcaa ctcggcgttg gggcgctccg
     7381 tgaagccggg gtacgcgacg atctccgggc cgatccgggc ggccagctcg ggggtcgcgt
     7441 cgtcgaccag cgagaccagg tggggcacgc cgttgtgcac cgccgtcacg tgcagcccgg
     7501 tgtccggccc gagccgcagg gaggcgccga ccagttcctc gccgtcggcg agcgcgggac
     7561 tgtggtgggt ccaggagccc aggtcgatgg tgccgggggc ggtgacgggg cggccgagcc
     7621 gcacgttcac ggcgccgccc ggggtacgca gggtgatctc gtcctgggtg gtgcggccgt
     7681 gctcgcgcag gtaccgggcg aaaaggcgca ggccgttcgc gttgcgcgcg cactcggaac
     7741 cgtcggcgtt gaagacccgc acgtcgaagg tgtctgccgg cccggccgtc ggtcgcgtgg
     7801 cggggagcgg gccgtagagg accccgtcgg cgccgatgcc ggtgcgccgg tcgcacagga
     7861 cccgggtggc cgtggcgccc ggcgagggcg cgccgagttc cgggtcggcg acaaggtagt
     7921 cgttgccgag ggtgtggtac ttgaggaggg tggtcatcaa cgtccctcgc cgatggcttc
     7981 ttcctcgaag gtgtcgccgt accagcgctc gctccatcgc gagaacgaca ccaccgtgat
     8041 gtcgcggtgg ccttcctcct cgaccggcac gatgtcggtc acgtagtgcc acagcgcgcg
     8101 gtcgtcgaac gcgatagcct gtccggccgg cagcgtcgcg gtgaagatgg gggtctcctt
     8161 gtcctccgca ccgcgcagag tcagttcggc accggtgacg ccgacgcggt tgtagacgga
     8221 gatcaccacg aattcgtggc cgtcctggtg cacgccctcc gggacgacga cgccctgcag
     8281 ctccttgttg gcaatgaccc ggtactggtg gacgttgatc tgccagatgt cgttctcggg
     8341 cagcgggatc tgggcacagg cctcgcggat gtgctcgacc aggtcgatct ggatgggctg
     8401 gtagtgccgc cggatgccgc ccgcgatcgg gttgaacttg gagtaggtga cgtacgggcg
     8461 gtgcggcagc cgctcgaagt cccaggcccc gtcgcggtgt tcgagccggt actgggagaa
     8521 gcggcgccag cggttgccgt tgccgatgta ctcgtcgaag gcaaggtcgt cgaagctctt
     8581 gaggatgtcg tcccctgtct tggggaggtc gaagatcttg aagtgctgcg cgttgagagt
     8641 cacggtcgat gcctttcgcg gcggcggggc gacggggttc aggcgggctg gggctgcttc
     8701 aggcacacct cgaggacccg gtcgaggtac tgggcggagg tgttgagccg cacaaaggtg
     8761 ccgagggcga cctcgcggcc agcggcggga tcgcgctcga cgaccggccc gatgacgttc
     8821 ttgtaccagc cggccgcgtg gtgggcgtcg atgttgatgt ggatgtcgtg gtagatcttg
     8881 ccctccggcg ggagcccgag gcggtcccac gcggtgacca gctggcggaa gcggcggggg
     8941 gcgaggaact cggtgacgcc gtagtagccg atggcgcgca ggtagtggcg gcggctgagc
     9001 gcgaggccgg ccgagatgtt gccgcactcc ttggcgatgg gcagcaggtt ctgctcgacg
     9061 tagtcctggt cgacgccgat cgaggtgagg cactgggaga agagcgtcgt gtggacgtcg
     9121 gcgaactcgc cgttgcccat ctcgtcccag tagttggccg cgatctccat cttctcggcg
     9181 ccggtggcgc ccagctgcat gacggcgagg atgtcgtcga agcgcgggtc cagcgaggtc
     9241 tcctgggcga gcaggaagcg tatgtcctcg gcggtcgcca cggtcggcag gtgctcggcg
     9301 tacatcgggt gggtgctcgc cgggtggtcc tggatgaggg ccttcagcca gcgcacgtac
     9361 tccttcccgc cggtggggta gccgctcagc agctcctccg ggatctgccc gaactcgtgc
     9421 tccagcatgg cgttctcgag gatgctggtc acgtcgcaca ggaccggctg ggagtcctgg
     9481 tccgggttgc gggccgcgga ctggctgaac tcgtgggcgt agacgaccgc gagcacctcg
     9541 tgcaggtgtg cgcgcgctgc ggcgtcgcgg ccggtgaagg ccaggtccgc aaggcgtcgg
     9601 cactccccgg ccagttcggc gcggtgggcg tagtcgtcga cgagctgctg ccacttcgcg
     9661 taggccgacg aggtgagcgc cgccgtgaag ccggcgagga gcgggaagtg gttctgctgc
     9721 ggagcaggca tgccgggatc cctctcggtt gtcattcttt cggtccgctg acagggctcc
     9781 agatatcccc gttagcgaaa cgccgaacag atttcggctt cgattgatgc aagcctactc
     9841 agaggcgccg cacacggtcc aagtccaatt gtttatcgcg ctcatcagca gattttttca
     9901 gcgggctatc aagcgtttcc gagcctcgga aaagggaatg cggaagcgtc ggcggggcca
     9961 ccgtcggccg gtggttccgc cggcgctcgg ccggtgtgtg tcagtgatgc gtccggttga
    10021 tgatgccgac ggccgcgtcg agttccgcgg acacggtgtc ctcacccgtg ccgacggccc
    10081 agctcgcgcc gctactcaag taggcgatcg cgccgccctc cggcagttcg tgcgccgtgg
    10141 ccgaggtgag ggtcaggtcc agcccgagct gggtgagcgc gtcggcgaac gcgggcagcg
    10201 aagcgggtcc gttcagcggt atctccttgt cgatgccgtc caggcagacc gtcaccgagg
    10261 acggcgtacg gtccagcagc cgcagcacgc cgggcgggga ggtgtacgcg gtgtggaaga
    10321 gctcgcgcag ccgcttgggg ctgagttcgc cgccttcgcg gtccgtcacc tgctggacca
    10381 gtacggcgaa gtccgcgcgg agctgctggg gcaggcgcag tccgtaggag tcgttgagca
    10441 cgaacgccac tccgcccttg ccggactggg agttcacccg gacgaccggt tcgtactcgc
    10501 ggccgacgtc gcttgggtcg atcggcaggt agggcacctg ccagtgttcg tcgcgcaggt
    10561 cggagccgct ggagtgggac tcgtcggcga gtgccgagat ccccttgctg atggcgtcct
    10621 ggtggccgcc ggagaaggcg gtgaagacga gttcgccgcc ccacgggtgg cgttcgtgca
    10681 cgggcagttc ggtgcactcc tccaccaccc ggcggacctc gcccaggtcg gagaagtcga
    10741 tctcggggtc gacgccgcgg ctgaacatgt tcatgccgag cgtgaccagg cagacgttcc
    10801 cggtccgttc gccgttgccg aacaggcagc cctcgatgcg gtccgcgccg gcggccaaac
    10861 cgagttcggc ggcggcgacg gcggtgccgc ggtcgttgtg cgggtgcagc gagaggagga
    10921 ccgagtcacg ccgctccagg ttgcggctca tccactcgat cgagtctgcg taggtgttcg
    10981 gggtggtcat ctccacggtg gccggcaggc atatcgccgc cgggcgctgc ggggtgggct
    11041 gccagacgtc gaggaccgcg ttgcagacct cggcggcgaa gcccagctcg gtaccggtga
    11101 acgactccgg cgagtactgc agccgtacgt cggcgccggt gagcgactcg gccgcctccg
    11161 cgagccggcg ggccgacgcg acggccagct cgcggatctg cgtccgctcc tggcggaaga
    11221 ccacgcggcg ctgcagctcg gaggtcgggt tgtagatgtg cagggtcacc ttgcgggccc
    11281 cggcgacggc ctcgaccgtg cggtcgatga gttccggacg gcacggggag aggacctgga
    11341 ggcggacgtc gtccgggacg gtgtcactct cgatgatctc ccggacgaag gcgaggtccg
    11401 tcgcgctggc cgcggggaac ccgacctcga tctccttgta gcccatgccc acgagaagct
    11461 ggaagaactg gtgcttgcgg gccggggaca tcggcacggc gagggcctgg tttccgtcgc
    11521 gcagatcgac cgagcaccac agcggggcac gggtgatcgt ccggtccggc caggtccggt
    11581 ccggcagcag aactggttcg acctcctcgg cgtacgagcg gtagcggtgg accggcatgg
    11641 ggctcgggcg ctgctcgttc cagaccgggc gggtcgcgaa ttcgttcgtc atgggcactc
    11701 ctcgcgcatg aattgcaaaa tatgctagcc agcgaaagag aggccttcca gaaaattgcg
    11761 cagaagcgaa gtcggggaat aggaagcgcc attgcgcatt gccgcaacgg cattgacacc
    11821 ccttctttgg cgtcgcaata ctcaccaccg ttccgcagca gcggcatgat gacgaacgga
    11881 gagaagacgt ggcgccaacg tttgagatca aggggaacga cctctgggac ccgaccacgt
    11941 tcgacgcgct gcgccgccag ctgatcccgt cgttcgatct gatctacgag gccgcggtgc
    12001 gcacggtcgc ggcgaccgta ccagccgcgc cgcgcgtcct ggacctcggc gccggcaccg
    12061 gtctgctgag cgcggcgatc ctgcgtgacc tgcccgaggc gaacgtggtc ctcgtcgacc
    12121 gttcggagct gatgctgacg caggcacgcg gccggttcgc cagtcaggag cgggtcacgg
    12181 tgcagaccgg cgatctcacc gacccgcttc cggaggggca gttcgacgcg gtcgtctccg
    12241 gtctggccat ccaccacctg agccacaccg acaagcgcga cctgtttcgg cgcatccgcg
    12301 aggcgctgcg ccccggcggc gtcttcgtca acgtcgaaca ggtccagggc ccgctgccgc
    12361 atctggagtc cctctacgac agccagcacg agctgcacgt ggtgcgcgag caggctccgc
    12421 cggaggaatg ggcggccggc cgcgagcgga tgaaattcga cgtctgcacc gacctggaga
    12481 cccagttgca gtggctgcgt gacgccgggt tccgcagcgt cgactgcctc gccaaggact
    12541 tccgcttcgc cacctatgcg ggctgggtct cctgatgaca gcgctgtacc aggcggttcg
    12601 cgaggtcgcg cgacgtcggc cggacgcgat cgcggtcgag accacggccg gcgagcgcac
    12661 ctcgtatgct gagctgctcg cggcggccga ccgggtcgcg gcgggcctgc gcgcccacgg
    12721 cgtcgccgag ggacgcgtgg tcgtctgctc gggactggcc aacgacgcct cctacatggc
    12781 cttcctgctg ggagtatgcg tggccggtgc cgcctatgtg ccgctgctcg ccgacttcga
    12841 cgccgccgcc gtcgcgcgtg ccgtgcgttt gacccggccg gtgctctggg tcggccccga
    12901 gaaccaccac cgcgcgggcg tcaccgtgcc gcgcgtcgaa ctggccgagt tgtcggcccc
    12961 cggcgccccc gccacccctg gcatcgcgga cgccgacgtc gccccgcccg atcgcgcgtt
    13021 cgccccgggg accttccgga tgctgtggac gtccggctcc acgaaggcgc ccaagctcgt
    13081 cacctggcgc caggagccgt tcgtgcgtga gcgccggcgc tggatcgcct ccatcgaggc
    13141 gaccgagcac gacgcgttct tctgtcagca caccctcgac gtggcgcacg cgaccgactt
    13201 gcacgccttc gcggcgctgc tcgccggggc ccgtctggtc ctcgccgacc cgggcgcgga
    13261 accggcgacg ctgctggcgc agctggccgc gagcggtgcc acgtacacca gcatgctgcc
    13321 caaccactac gaggacctga tcgcggccgc cggacagcgg cccggaaccg atctgtcccg
    13381 gctgcgccgg ccgatgtgcg gcggcgcgta cgccggcccg gcactgatcg cgagcgccgc
    13441 cgaggtgctc ggcatccaca tccgccacat ctacggctcg accgagttcg gcctcgccct
    13501 cggcaacatg gcggacgagg tgcagaccct cggcggtatg cacgaggtcg cgggggtacg
    13561 cgcccggctg gagccgctcg ccggatacga ctgggacgac ctcggcaccc tggtgctcac
    13621 ctccgactgc acgagcgacg gctacgtgga cgacgacgag gccaacgcgg ccaccttccg
    13681 cggctccgat ttctggaccg gtgacgtcgc ccagcgtctg gacggcggcg gcttccgtct
    13741 cctcgggcgg gttaccgacc tgctgctggc gacggacggt ccgctggccg ctcccttcct
    13801 cgacgaactc atcgcccggg actgcccggt cgccgagtcc gtgagtctca ccgccgacac
    13861 ggacagcctc accaaccgtg tgctcgtggt gctgcgcgcg gcaccgggaa cctccgatga
    13921 cgacgccgtc ggcgccgtcg acaagctcct cgcgtcgcac gggctgaccg gcccggtcct
    13981 ggcgttcgag cggatcccgc gcacggttgt cggcaaggcc gaccgcgcgc tgctgcgcag
    14041 ccgctacctc gcggcatcga gttcctcctg acgcgccacc ttcggcgaca tgctctgaaa
    14101 gggcgagtca tgacccggaa gaccctggta gacaagatct gggacctgca cgtcgtggag
    14161 cccggggcat ccgacctcct ctacatcgac ctgcacctgc tgcacgaggt cagttcgccc
    14221 caggcgttcg ccgggctgcg cgaggccggc cgtacggtgc gccgtcccgc gctcgcggtc
    14281 gccaccaccg accacgacgt gccgaccgac gggcgtgagc tgtcgccgga cgcgggcgcc
    14341 gccaagcagg tgcgggtgct cgccgacaac tgccgggaca acgagatcga gttgcacccg
    14401 gtcggcagtc cggggcaggg catcgtgcat gtgatcggcc cgcagatggg actcacccgg
    14461 cccggtacga ccatcgtctg cggcgacagc cacaccgcga cccacggcgc gttcggtgcc
    14521 atcgcgttcg gcatcggcac cagcgagatc gagcacgtcc tcgccacgca gaccctgcgg
    14581 gcacgccggc cggagtccat ggcggtgacg gtcaccggtg acctcctgcc cggcgccacc
    14641 gccaaggacc tcgcgctcgg catcctcgcg gccggcggca cggacgcggg caccggaacg
    14701 ctcatcgagt tccgcggccc ggctgtgcgc gcgctgtcca tggaaggacg gatgacgctg
    14761 tgcaacatgg ccgtcgagat gggcgcgcgc agtggtctgg tagcccccga cgagacgacg
    14821 ttcgcgtatc tgaaggaccg cccccgtgcc ccgcgtggtg atctgtggga ccaagcgatt
    14881 gccgaatggc ggacgttgcg cagcggcccg gacgccgtgt tcgcccgtga actggtcgtc
    14941 gacgcgggct cgatcgtgcc acgggtgacc tggggcacca accccgggca gagcgtgccg
    15001 gtcgacggtg cggtccccca ccccgccgac agcgcggacc ccggcgagcg ggccgccgcg
    15061 gagcgcgccc tgacctacat gggcctgcgt cccggcaccc cgatgcgcga cgtcggcatc
    15121 gacgtggtct tcatcggctc ctgcaccaac agccggatcg aggacctgcg cgccgccgcc
    15181 gatgtgctgc gcgggcggcg ggtggccgac ggtgtccgcg gtctggtcgt ccccggctcg
    15241 atgctggtgc gggaccaggc cgaacgggag ggtctcgacc gggtcttcac cgccgcgggg
    15301 ttcgagtggc ggatgccggg ctgctcgatg tgcgtcggca tcaacggtga cacggtcgca
    15361 ccggggcagc gctgtgcctc gacctccaac cgcaacttcg aaggccggca gggtgtcggg
    15421 gcccggacgc acctcgtctc gcccgccacg gccgccgcca ccgccgtcgc cgggcgtttc
    15481 gccacgccgg ccgacctgta gggagaagcg catggaaccg ctcgtccgcg tcaccggccg
    15541 cggggtgcct ctggaccggc ccaatgtcga caccgaccag atcatcccgg ccgcctggct
    15601 gaagaacacc acccgcaccg gttacgccga cggcctgttc gagcagtggc gcctcgaccc
    15661 ggacttcgtc ctcaaccggc ccgagcgcgt cggtgcctcg gtcctggtca gcgggcccaa
    15721 tttcggctgc ggttcgtcgc gtgagcacgc gccgtgggca ctgcacgagt ggggcttccg
    15781 ggcggtgatc gcgccgggat tcgcggacat cttccgcaac aacatgccga acgccggcct
    15841 ggtgcccgtg tggtgcgagc cggacgtggt ggccgccctg atggcggcca ccaccacctg
    15901 cgccaccgcc gagatctgtg tcgacgtggc cgcgcgcatc gtcacctgcg aggccgcggg
    15961 cgtcggggcg gcgccgttcc ggctcgacga cgacgcccgt gaccggctcg tcgccggact
    16021 gacccagctg gaggtgacgc tgcgcgccgc cgaccggatc gcggcgttcg agcgggcccg
    16081 cgcgccctgg ctgcacatct ccgcctgagg ctggcgccgc ggcgcacgag acggaagggg
    16141 gtatgtgtcc cggggcggag gccctggaca cataccccct tccgtgcgtc ccgggcggcc
    16201 tgcgggtgcg ggacgcgtcc ccggaggcgg gaaccggcag ctcaaacgcg cgatgttccc
    16261 ctccgctctc gcggccctgc acgagcccgc ctcccacacc tactacgacc gctgccgagc
    16321 acgcggcaaa acccacgccc agtccctcct ccgccccgtc cgccaccgca tcggcgtccc
    16381 gctcgccatg ctccgcgacg gcaccttcta cgagccgagg aactcccgaa ccgctcgacg
    16441 aaggacatag aggcccccca cgtccactgg ccgtccggtt tcgcgcccgg tcggactcac
    16501 ggcttctgcc aggcgcagac ggccgcccgg tgcaggcggc ggacatcgtt gtagacactc
    16561 tgctgcatgg accgggagcg gcctgacacc ccgatgggcc agcaggccct cgcggtccgc
    16621 cgctcgtctc cttccagggt ctggtgtgcg ggcgggcggt cagttcttct gccggtgcgg
    16681 atgcgcggga tacaccccta ggatgcgcac ctccgaggag aagaaccgca acccgtgcat
    16741 ggccaggtcg acgcgggggt catcggggtg cccctcgatc tcgatataga agcggacggc
    16801 gttgagacct gcgcacaccg gtagctctcg atcttcgtga ggttcacccc gccggcggcg
    16861 aacccgcggg ggcggccgag tccggcccgg ggaacgcgga tcttgtccat gaccggcgca
    16921 caccgggctg cggaccactg agatcatccg cgagatgacc ggcgcacccg gcgagcgggt
    16981 cgcggtcctg tccggcccga acctggcccg cgagatcatg gccgaacagc cggccgccgc
    17041 taccatcgcc tgcccggacg aggaagccgc ccgccgcttt cagacggcct gtcacacccc
    17101 gtacttccgg cactcccagg gtgaagaagc ctggcggatt ggacccgcct gtccgagtcg
    17161 gggacaacgg ccgcacggtg gtctcgcagg ccggagcggt cctgctgtgg agacagtccg
    17221 caagagcggc gtggatgctg cgttgtcggc ggcgctggcg ccgtggtgca aggcgcggcg
    17281 gtgcacgacc caggcaagat cctgctggac cttgcgctgg cgaccaccct gggcggggac
    17341 tgcctggccg atgtcgcgat actgagggcc gaaccagccc tcttcgggcc ggtggcctgc
    17401 ggcccgaccg tctcccgcct catcgacgcg ctcgccgcag cgggctcccg ggcactggcc
    17461 gccatccgca ccgcacgggc cgaagtccgc gaacacatct ggcagctgac cgggaccggc
    17521 gccccgcacg ccgacgggca ggtgatcgtg gacatcgacg gcgtgctggt actggcccac
    17581 tccggcaagg aggacgccac acggacctgg aagaagacct atgggcgtca tccgctcatg
    17641 gccttcgtcg accacgggcg cggcggcacc tgagagccgg tcgcggggct gcggcggcca
    17701 ggcagggcgg gccaccggcc ttaccaacct gcctctccac gacaccgcgc agaaccagat
    17761 ctggctggag atcctccaga tcgccctcga cctgctggcc tggatgccga tgctggccct
    17821 gatcggcccc gccgggctgt gggaacccaa gcgcctgagg ctgcggctgt tctccgccgc
    17881 cgtggcctgt gagggcctgc ggacatcgcc ttcgccgacc gtcacgcggc aacttccgca
    17941 actgggcccg gctcaccgcc cacacgatga ccgcgcttga acgaacaggg cgagaccatc
    18001 cggaccgggc atccggttgg tcgacggcgt cctccacctc cgacagcgac aactctccgg
    18061 tcaggaccca gctcggttcc tgaggtcccg gggttccgtc cgtctacccg tccgcgcgcc
    18121 ctcgccgcct gccaggcacg aaccgtcctc gtcgccgcgg gcctcccctc cacggcgcta
    18181 cggtcagacc gtccgccgcg ccccgcgggg cgtgttacgc gctgctgccc agcgcgtcct
    18241 gccagactgc ggccggcgtc ttgttggtcc gcgtgatgcg gcgcagccgc tcgacccggc
    18301 aggcggagat cgcctcgggg tgctggctgt cgacggtgcc gagtcgcaca tggccacccg
    18361 tcagccagtt ccggacggtc tccggggcag ccgtgccggt gtactcgacg gtcatcgacc
    18421 gcgcggagtc cgccaagtcg gtgtcgcgga ccagcacgat ctgggcgtcc acgacgtccg
    18481 ggcattgccg ggcacggtcg acgatgtccg cgatgttgac gaagttgccg agcagaccga
    18541 aaccgtcgtc ggcgcgtccc agcacacgaa aggcgtcgcc gcgtccgcaa cggcactccg
    18601 ccgcctcgat gcggtcgccg agacggtagc ggacgacggg gacggtccat ccgtcaccgg
    18661 cccgggtcag cagggcgccc gcgtcctcca gctcgaagat ctggtcctcg agcagatgca
    18721 gcgtggtctc gtcgcacccc ggccggttgg agcccatcgc ccaggtctcg accgagccgt
    18781 agatgcccca cagctgcacg tcggggaagg cctgccggac cagctcccgc ttggcatccg
    18841 tccatgcctc gcccatccag atgatggtct tgacgggcgg cttcaccccg gtcttgagca
    18901 cggtctcggc gaagtcggcg agcacggagg gaacgctggc cagcgcgctg acgccgacct
    18961 cgcgaagcat gggcagccgg agttcgagct cctcggtcgt catcggcccc gaggggatca
    19021 ccgtggattc ggtgcactcg gcgatcttct ggacgaagta gtgggtgccc cacatgcggc
    19081 cggcgtcgta gaggttgagc acgacgtcgc cgacgcccag cgggcgccag acggacagga
    19141 gccggtcgaa ggccatgtgg tggggcaggt aggtcagttt cggggtgccg gtggtgccac
    19201 cgctggagac gagcacgctg ccgtcccgct cggccgccgc cctggttatc gcggtgatct
    19261 cggcggggcc acagatctcc aggtcggaaa gcactttcgc accgtcgggg accggcttgc
    19321 caccggacgc ggcgatcgtc cgggcgtgag cgagcaaggt ctccgggtcg atggatccga
    19381 tcatgattct cctggcacat cgatgaaggg acacggccac gtgcgaaagg gactgccgaa
    19441 atggtgtgtc gattgtttcg agataattca cacgccgtgt gacatcaggt caaatggatc
    19501 ctaggcagcc cgcctcgagt cggtccaata atgatttttg atcaaccgat aacaagtact
    19561 gaaaggcttc ggcattgtcg gcgcactact ccgcggggaa aatagcggga tgaatactaa
    19621 gaccgtcgtg ctcgtgggag tcccgtggaa cgtccatgaa ctggacgacg cggtccgtga
    19681 cgcggccacg ctcggcgcct cgctcctcct cgtcgacact cccgagtccc tcgctcagat
    19741 cggcgaacag accgccgtcg agacccgcag cgtcaaggcg ctcgacccgt tgctcatcgc
    19801 cgactgcgtg cgcgacgccg aaccggccac cgtcctcgcc atcaccgagt tctgcatgga
    19861 gctggcggcg gccgtgcgcg agcggctcgg catcgccggg acgccgccca ccgtcgaggc
    19921 ccgggtcctg gacaaggcgg cgacccgcga agtgctgcgc gagcacgggc tcacccaggt
    19981 gggcttccac cggacttcgc tactctccac cgacgacctg ctcggcggtc tggagccgcc
    20041 ggtggtggtc aagccacgcg cgttcagcgg cagtcacggc gtcacgttcg tcaccgaccg
    20101 ttccgaactg gcgcgggtct tcgagccgta cgacctggcg gaggccaacc acgtcgaccg
    20161 tgacacccgg gtggcccatc tcaccgggga ccaccgcacg cacgaggtga tcgtcgagga
    20221 gtacgtgcca gggcccgaga tcagtgcgga gggactcgtc gtcgacggcc ggctcacgct
    20281 gttcaccctg accgacaagg tcaacaccgg aatgccgcac ttcgaggaaa tcggccacgt
    20341 ggtgcccagc aggtacacgg aggagcggaa ggcgcaggtc gaggagtacc tgcaggccgt
    20401 cgtgtccgcg ctgggtttcg tcacttcgcc gatgcacgcc gagatcaagc tgctcgacga
    20461 ccggatcgag ctggttgaga tccacacccg ctatcccggc gaccgcgtgg tcgaactgct
    20521 ggagtcggct tacgagatac ggccgtacga ggcctacttc gacgccatgg tcaacggccg
    20581 cgctccggtg ccgccccggc cgaccggtgt ttaccacggc gtcggcttct tcaactgctc
    20641 gacgaccgcc cccttcacct ggccgtccta cgccttcccg caccccgagg ccgtcgtctc
    20701 ggtcgacctc gaccgccgca gggctccgag ggtcttcgcg tacgagggcc tgcgcatcag
    20761 gtactggcgg gcgggccacg tcctgttcgc gtcggaggac cacgcctccg tccacgcgaa
    20821 catcggcttc ctgttcgaca acacaccccg acagggcggt tccgggagct agtagggcct
    20881 ggtcaggttg gggtcgccgt gggtatgcca cggtgacagg tggggcaggc gccggtccag
    20941 atcgcgagga gtaactgcat tgcgcggacg acctggaaga ggctcagacc ggcgccgtct
    21001 cttttggggt ccggaccatg cgttggagcg tgcagaaggc gtgggcggcg gagacgaggg
    21061 tgacatggtg gtgccagccg ttccaggtgt ggccctcgaa gtgggccggg cccacctgtt
    21121 tcatctcgcg gcagtcgtgc tcgatgcgcc ggcgaagcgt ggccggccgc accagcgtgc
    21181 ggagcggagc gtcgtcgggc aggttggaga gccagaaccg caccggcctc cggtgcggtg
    21241 gcgggccact ccgccagcag ccagctccgc tccctcgacg gcctggattt cacgtccggc
    21301 gggcgggata cgcagcgcca cgaaccgcga atacatgcgt tggaacccgc tgtggccgct
    21361 gcctgggcgg gagccctccc gccactgcac ggaccgggcc gcccgcttcc ccgtagcgat
    21421 gaccagctat ttaaagctcc tcggcgcctg ggggtaggcc ggctggggcg gacgtccgcg
    21481 gccgctgtgg gacgacgggc acggcgttgc gtcatgcgtg tgggccgtga cggtggtcga
    21541 agtgcccacc acgtagtgca gcccacgctc ctcgaggccg agccggaagg ccgcggtgtc
    21601 tccgtagccg ccgtcggcca cgaccaaagg agcatcgacg ctccaaaacc tgctctcgtc
    21661 ggtcatgtcc agggccagtt gccacttctc gacatgaccc acgtccggcg ggatgccgca
    21721 ccgctcacgg cgggccacct tcgcgagatc ggcctgcggc gaggcgggat cccagctcct
    21781 gggcaggaac aggcgccagt cgatcgccgc cgaggcggtg tccgaggcca gatgcaagga
    21841 cacgcccgcc tggcagttgg tgaccttgcc agcggtgccg gtgtactgcc gcgacacaca
    21901 caccgaggca tcaccgtctt tgaggaggcc ggtgtcatca atgatcagcg cggtcgggtt
    21961 gatcgccggg accattcttc acgcgaggcg ggcccgcaca tgcgccggat cccacgggct
    22021 ggtggtgatg aagtgggcca gagcctgccg gttcacccag ccgggcggcc atcggctcca
    22081 ccgatttgcg ctgcccgtcc agcagcagac cccgcagata caccccgcac caccgacgct
    22141 gatccgcccg cccgaacgac tcgaacacat ccgccgcgaa gtcctccaga cggcaccgga
    22201 cttcatccaa ctcctcaggt gtcacaaacc agtcaacgat accgcccgtc aaccaggcac
    22261 gccgccgaca aatgaacctg accaggcact actggccagc cactcccgtc ggaagccccg
    22321 gacggtgacc gtacgctcga cgcgcgcggt caccgtccgg ttcgtccccc gtcacacccc
    22381 gtcgccgatc ggtcacctct cgacggccgt tcgctcgccg ttggtccact tcccgtcact
    22441 ccgacggcag cggccgggtg tgcacggcgg gatcgggcct ctcgcggggc agtgccaggc
    22501 aggcgagggc gcccagggcg agggccgcga ccggcaggaa cgtggcggcg cgcatcgccg
    22561 tgctgctgcc gcccgccacc gattccaggc cctgtgccag cgccacgacg cccgcggtga
    22621 agaccatcgc gccgacctgg cgcatcgtct ccaggatccc ggaggcggca cccgtcagtt
    22681 cctgggggac gtcgcgcatc gcgaccgtcg tcctcggcgc gatcgagcag ccgttgccca
    22741 tgccgatgac cgtcatgggg gccaggaagt cctcaccgtg cgccgagccg gtcatcagca
    22801 gcgcggtcca caggatgccc gctccctgga cgaccatgcc ggtcagcagg atgaagcggc
    22861 cctcgacccg gtcggccagg cggccggcga cgagcgcgac cagcacggac atggccgacg
    22921 ccggcgccag gacgacgccc gcccggaagg cgctgaggcc gactacggac tggaagtaca
    22981 gcgcggccac cacggtgata ccgaaggtgg caccggtgat cgcggcggcg atcccgagtg
    23041 tcacggtgta gccgcggatc cgcaggaggg cgaaggggac cagcggatcg tcgttctggc
    23101 gctgccgctg acgggccgtg aagccgacgc cgaagagcgc ggccgccgcc agcagcgccc
    23161 agatgagggg gccccagtgg tgatcggcgc cgttggtcac ggcgtaggcg aagcaggcga
    23221 gggccagcga ggcgatgacg acaccgggca ggtcgaggga gtgccggcgg tccgtccgca
    23281 ggtccgggac gaccgtcagg cccgccgcca cgacgagcac gccgatcggc aggttgatga
    23341 ggaagatcca ccgccagccg gccaggttga tcaacaggcc gccgagggag gggccgagca
    23401 ccgaggccac cccgccgatc gcgccccaca ccccgagtgc cgtaccgcgc cgttcgcgcg
    23461 ggaacgaggc cacgatcagg gtgacgctct ggggcatgag cagcgcggca cccgcgccct
    23521 gcagcacacg tgccgccacc aggacgccgg ggaccgtcgc gagcccgcac agcaggctcg
    23581 cgacggtgaa cagcagcacg cccgccacga acacctgccg cgggccgtac cggtcgccca
    23641 gacggcccgc agtgatcagc aggacggtga tggcgatgat gtagctgttc agcgcccaca
    23701 gcacctgcgg cagggtggcg tgcatcgagt cgatgatgct ggggatcgcg atggtgacga
    23761 tcgtcgagtc cagcagggtc atgaagtacc ccagggacag cacgaccagt gtcgcccagg
    23821 ggttggcgcg cagccgggtc acgcgcccgc cgtcccgtcc acgaagtcac ggagcacgcg
    23881 gacgaaccgg ccgggctcct ccaggaagag ggcgtggccg ctttcggaga acatctcgag
    23941 ccgggcgtcg ggaagcgcgc ccagcagcca cttgccgacc tcggtgggaa agatccggga
    24001 cttcgcgccg tgcacgagca gcgtcggcag cgtcagcgcg cctatccgct cgcgccagtc
    24061 ctgggtgagg acgccgctcc acagggccag cagcgcaagc cgtgaggtct tcagcgagtc
    24121 ggccaacagg agctgcgtca gggctggttc ggggtccgct ccggcagcga agcagttctc
    24181 gacgagggcg gtgaggtatc tgtccgggtc ggcccactgc tgctgggtgg cgtgcagcgc
    24241 gccgaaggcg tccagaccgc cgaacgccgc gtgctcccag ccctcctcgc gcagcaggta
    24301 cggggacatc tccacggaga ccagccggga aacccgatcg gtgccgtacc gctcgaggta
    24361 gttgtaggtg acggtcgcgc cgagcgacca gccgacgagc gtgacgtcgt gtaggtcgag
    24421 tcggtcgatg acctgcgcca ggtcggcggc cgcgtcgtca agcgtccagc cgggcggcgg
    24481 cgtggggctg gagccgtgtc cgcgcaggtc cacggtgacg acgtcgtagc cggggccgag
    24541 gcccgccgtc gtgtgcgcga aggactgcga ggtcatcccc aggcccggaa cgaacagcac
    24601 gatcggcccg gcaccggggc gccggacatg atgcatcact tcgagcacgg tgagagctcc
    24661 aatcaatttc cgggatgcgg tgatcaaaat ataggaccag cccatgaaac ccggcaccga
    24721 actgtgatca aattttccta tgaccgcccg tcccgcaatc gcacgcatta ccagcgtcga
    24781 tagacgggct ttatagggcc aggtcaaccg gcatcggaac ctgaccgaga tcccgagatc
    24841 cggataggtt ctgccgcaaa tattattgac tgcgcattac cggccgagtc gacttccggg
    24901 cgacaaatta cgcggggacg gcatcgggtt acgcatggac ggcaccgggt cgcggacgga
    24961 ggccatcggg ggcccttcgg acgcgtcggg gacgtccggg cagaccaggc gcgtcggagg
    25021 acgagccgag aggtgtcggg gacacgcccg ggggactgga gacgtactcc ggtcgcgtcg
    25081 gcgagcgtcg gacgggcgga cgagtccgcc gcaaccgcag gggggcaagg tcaggaccgg
    25141 gaagttactg accttgctgg cgtgatgtcg cgggggctga caagcagtgg gattcgcagt
    25201 agtccggttg catgaggtat ccgcaagggg gcgggctgac cacggagcga cgggtgtttc
    25261 gcgagcacat ccggatgcgg gcggccgagt tattcgccct gggacacgac aacgccacca
    25321 tcgccaaaca gttgcgcgtc agcgtgcggt cggtgcagcg gtggcaccgg gcatgggagc
    25381 acggtggaac cacagccctg gagtcgaagg ggccggcgtc ccatcccaag ctgagtgagg
    25441 cgctgttcga ggtgctcgag caggagctgg ccaaggggcc ggtagcgcac ggctggccgg
    25501 accagacctg gacgctggcg cggatcaaga cgctgatcgg gcgccggttc cacaagagca
    25561 tgacgctgtc ggccatcgcg cagatgctgc accggcacgg cttcagccac caggtccccg
    25621 cccgccgcgc gaccgagcgc ggcgaggaag ccgtcaccgg gtgggtgaag gagacagggc
    25681 cccaggcgga aacgccgtgg cggcgctcgg ggcctggctg tgcttcgagg acgaagccgg
    25741 cttctcgatg acgcgcccac cgcacggacc tgggcccggc gcggacacac acccgtcatc
    25801 cgggtgcggg gacgctccca gcgccgcttc tccatcgccg ctctgacctg ctacaagcag
    25861 ggtgaacgct cacgcctgat ctaccggccc aaacggcacg ccgatcacaa gcggggcggc
    25921 agacgcagtt tcacctggac cgactaccgc gacctgctca tcgccgccca ccagcaactc
    25981 ggcgcaccaa tcgtccttgt gtgggacaac ctgaacgtgc acagagaccg ccggctgagg
    26041 aagttcatcg acacccatga ctggatcacc tgctacttcc tgccgtccta tgcgccggac
    26101 ctcaaccccg tcgagggcgt ctggtcactg ctgcggcgca gcagccaggt caacaccgcc
    26161 ttcacggacc ccgaccacct catgtgtgca cttcggcatg gtctccgcca gatccagtac
    26221 cgcagcgacc tcgtcgatgg atgtctcgct ggaaccggcc tcaccttgac gacatcacgc
    26281 cagcaaggtc agtagcggct gtcgatcagc gcccaccgcg tcggacaggt ccgtcgcgta
    26341 ggagcttgcg ccttcttgca gcctgtggaa tcaccgtcgg cctcgccgcc ggagccgcag
    26401 tgatagcagt cccgctggcc gccaccagtg ctgtcgccgt ccccccgccc ggcagcggct
    26461 ggcacgtggc tggcggtatg acgtatgacg cgaagatgca gtgcgaggct gaggaactgc
    26521 cgtacgccca gcagaacggg tatgacgagg tgtggtgcga cggtccgggt ggtcgcgccg
    26581 agtacaccgt ctgggtgcgc tgaccacttc ccgaggcgca gaacggtcgg ccgccctggc
    26641 gcgctgcgcc ggggcggccc ggctccccga tgtctcacca accgccccgg tccatctact
    26701 gccgcttggg tcgcaggccc gtgggtggga ggtcccccgg cccgcgagca gcgccgatcc
    26761 tcgtcaccga gcgggaccag caccacgagc cggtctcgcc ggccctccct ggggaccggc
    26821 gagaccggct cgcgtctgga gtcaccggac agggcgtggc gccgtcgtca gggctcctgc
    26881 tgccggcgcg ggtatcccga cccgtcgtac cgtccgcggc gtgttgtggt cgctcaggtg
    26941 gtgacgggat ctcccacggc tccgccggtg gccgtgcgta ccgctcgtgc gatccgggca
    27001 ggcgcgtcgg cgaagtcccg gggatcggtg ccctccagga tggcggcgcc gatgtgctcg
    27061 ttgaggaccc gcagcgcggc cgaggccgca gcggcgtgca ggcgtacgtc gaggtcctcg
    27121 gccggaagtc cgagtcgctc cgcgatgatc tcggccatct cgcgctctac ttggtcgcat
    27181 gccatcagcc aggccgtacg gatggccggc tccgtgtcgg ccagccggat catcttgatc
    27241 gcgagctcgg tgtccatccg ctccacgtca ctggcctcac gaccgaactt gctgctctcc
    27301 gcggcgaagt gcacttccag cgagagctgc ggaggccagc tgcgcagcgt ggacatctcc
    27361 cactccacgc cccgcatcac gatgggctcg gcgcagctct ccttgctgcg gaagtggcgc
    27421 cagatggtgc gcgtcgacag gcccacggcc tcggcgatct ggtctccgct ggtcgcgtcg
    27481 acgccctgcg cccagaagag ccgggacgct tcccgtgaga catccagacg caggcggtgg
    27541 cgccgctgat cactcatgcc gccacgtccc ctggtcggtg ccgtaccggc catcccttta
    27601 ctccttgctc ccgactgcaa gtgaaaggat ggcatttagt gacgccaatg accagccagt
    27661 gaatacgacg gagctggtcc tcacgacggg tcttgctcga cggctccggt gtccatggca
    27721 agggggcggg gtccacacca cgggggccgc gaagctacgg gccggcctgc cgtccgaccg
    27781 gcccgtcgcc gggaagcccg cgggtgggta gtacggggcc gaccacgacg tgggcgtcac
    27841 ctggccccgg ggcgctctcc ctcgtcggca tggccgtacg gacgaccaag gccccggggc
    27901 gctccctcat cgtcggccgt cctgacgacc gagagtgaac cctggacgga tgagtccgat
    27961 gcgcggcaac ctcgacgcgt tcgtggagcg ggtcttccac tgggaccgac aggggctcca
    28021 cggccatcgt cgccgagccc ctgtccactc ctcgaaccac cgtcaggaag gcgatacggc
    28081 agctcgcaac ggacacggac ttctgtaccc gcttcttctg ggggctgcgc ctgggcagtt
    28141 ggacctggag cagcacggcg aacggacctt cgagggcgtc gccgtccgtg tcgcccagcg
    28201 catcctcgcc atggccgccg ctatctggcg taaccacagg accggcgccc cgagcacgcg
    28261 gtcgctggcc gcattcgatc actgaatacg gacttatccg tctgggcccg gcgaagatcc
    28321 gctgatcgcc cgcccagcca gtcgatcacg aagggtgccc gggacgatcc accgtcccgg
    28381 ccaccctgct gttccggcct cgttcgttac ggccgccgcc cggaccggac ggaaccgacc
    28441 cctggccggg gggctcctcc accgcccctg gtcgacccct cggcgacgtc ggcacggggc
    28501 gtgtcggcgg gggccgggag ggcgcggccg ccggtggcga tggcgctctc ctcggcgagt
    28561 cgctccgtgc tggtggtcgt cttgagcggc ttctcctcga tgaacaggac gacgatcagc
    28621 gccagcaggg cgaacggggt ggcccagagg aagagttcgg cggtggcggt gccgtaggcg
    28681 ttctccacga gcgcacgcaa gggggcgggc agggtcgtcg gttcggggac accgtgcccg
    28741 gctccgcctc ccggcgtgtc acctcccgcc gcgccgccgg cggacagctc ggtggcgacg
    28801 cggtgggcga ggaccgcccc gaggacgctg gtgcccacgg tcccgcccat gctgcgcgag
    28861 aaggacagga cggaggtggc gctgcccaga gtgttggcgg gcacgtcgtt ctgcgcggcg
    28921 agggccaggt tctgcatcag catgccgacg ccggtcccca ggacggccat gtagacgctc
    28981 agcagaacga agggcgtgtg ggatccgatg gtggacagca gggcgaggcc ggcggtcatg
    29041 aggacggtgc ctgccacgag gtaccgcttc cacctgccgg tcgcgctgat ccggtgtccg
    29101 gcgaacgtgg aggcggtgag cgatcccagg atcagcggca ggctcatcag accggcggtc
    29161 gtgggcgact ttcccatggc cacctggaag aactgcgaga ggaagacggt gccgccgaag
    29221 aggccgacac cggccagcag ggaggccagg ctggtcagcg ccacggtgcg gatgcggaag
    29281 atgctcagcg ggatgatcgg ctcggcggcc cgggactcga cccggacggc cgccgccagc
    29341 agcagcgtgc cgccaccgac cagggcggcc gtctgccagg agaa
//
