LOCUS       NZ_CP019458            29803 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 chromosome, complete
            genome.
ACCESSION   NZ_CP019458
VERSION     NZ_CP019458.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6619584
            Orig. end                         :: 6649387
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019458.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29803
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="30"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29803
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29803
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15803](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15803)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            1070..1660
                     /locus_tag="BV401_RS27000"
                     /old_locus_tag="BV401_27045"
     CDS             1070..1660
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060847.1"
                     /locus_tag="BV401_RS27000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27045"
                     /product="hypothetical protein"
                     /protein_id="WP_079258670.1"
                     /transl_table=11
                     /translation="MSTETLLWTPPNTEDVEALPVGRWWDAVRAAPTVGERALGLLGDE
                     TGAVIQDKHGPLYWLIAVGSATSWHLRQVRVLTELTDASTYLGVPPAAWTKGPRTHWRV
                     PLSADHYLTDARRLWEALAEADRAEYGRMPEGRQLCHRCHLPTDEPIPVEAEDTRGAVG
                     KATYACPAHALHPKPQHPRTPTNAAAAEHEGRR"
     misc_feature    1124..1126
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1657..2085
                     /locus_tag="BV401_RS44975"
     CDS             1657..2085
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061330.1"
                     /locus_tag="BV401_RS44975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_237287832.1"
                     /transl_table=11
                     /translation="MKKSHEADIARPGPAGINPDTLTYQQLQGWNCALCGRPLGADRPL
                     GAERPLGVDRPLGTDRPLGTVTIERDATRTTYEVRACAPSCAETSTGPAAETEWREAIE
                     HAAGCPACRTPGAGCETGERLLHTYEEAARQARSGEGI"
     misc_feature    1756..1758
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2224..3132)
                     /locus_tag="BV401_RS27010"
                     /old_locus_tag="BV401_27055"
     CDS             complement(2224..3132)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012517.4"
                     /locus_tag="BV401_RS27010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27055"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_079258671.1"
                     /transl_table=11
                     /translation="MEIGVGLPGHVTGLEERTLVTWARRAEERGFASLTASDRLAWSTP
                     EPLITLAAAAGATERIRLVTSVLLAPLHTNPALFAKAAATLDRIAGAGRLHLGLAPGAR
                     EDDYQASHLDFSTRGRALDTLVERVTAIWRGEEEVGPAPATPAGPPLWFGGTSQATLRR
                     ITSHGTGWIAGTGGDIDEFTTFATRLHSHWKEAGRQGRPRTRATAMFALGGHAHQSLTR
                     AVNDYYAFAGPDYVRTVIDTAATTADMIHTTVTTHETAGLDELVFVGNHTDPKQIDLLA
                     DILGDKLTSPNSTTRAPDRSH"
     gene            complement(3274..4011)
                     /locus_tag="BV401_RS27015"
                     /old_locus_tag="BV401_27060"
     CDS             complement(3274..4011)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 2.3e-13. Score:
                     42.4. Matches aSDomain:
                     nrpspksdomains_BV401_RS27015_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="BV401_RS27015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27060"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_069864923.1"
                     /sec_met_domain="adh_short (E-value: 1.7e-35, bitscore:
                     121.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISGAVVLVTGASSGIGGATARAASRAGARVVLLARREERIRQL
                     AGELGESVALAVPCDVTDRVQVTAAVEAAIEKFGRIDILVNNAGQGLQATVDAIDPEDF
                     RAVLELNLLAPLTTTQAVLPQMRKQGAGAIVNVGSGIIWSSLPGSGAYSASKAALAKLS
                     AIARAELADDNITVSMMFPSITETEFVRTVRGDVAGALKMEDSSGLAPQSPEGAADTIL
                     DLIRSGAEQADLVPEEYGGTLKN"
     aSDomain        complement(3505..3993)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS27015_PKS_KR.1"
                     /evalue="2.30E-13"
                     /label="BV401_RS27015_PKS_KR.1"
                     /locus_tag="BV401_RS27015"
                     /protein_end="169"
                     /protein_start="6"
                     /score="42.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGGATARAASRAGARVVLLARREERIRQLAGELGE
                     SVALAVPCDVTDRVQVTAAVEAAIEKFGRIDILVNNAGQGLQATVDAIDPEDFRAVLEL
                     NLLAPLTTTQAVLPQMRKQGAGAIVNVGSGIIWSSLPGSGAYSASKAALAKLSAIARAE
                     "
     CDS_motif       complement(3850..3993)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS27015_0001"
                     /evalue="4.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="BV401_RS27015"
                     /protein_end="54"
                     /protein_start="6"
                     /score="13.1"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGGATARAASRAGARVVLLARREERIRQLAGELGE
                     SVA"
     misc_feature    complement(4101..4114)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            4139..4642
                     /locus_tag="BV401_RS27020"
                     /old_locus_tag="BV401_27065"
     CDS             4139..4642
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="BV401_RS27020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27065"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_079258672.1"
                     /transl_table=11
                     /translation="MSDVNAASLHELADLVFAVGRQLRPPADPAFEPCTPIEISVMRFI
                     HHHPGTSARAASEATLLPSSNFSRVLRGLEKRGLVERVVDDRNARGVRLYPTDKAHRNH
                     QILRDNWDRTLRGIIDDPATIEIVNATLRRIEDELIARRSGTDSDRDQTDQPRAFARPA
                     DWRS"
     gene            complement(4864..5427)
                     /locus_tag="BV401_RS27025"
                     /old_locus_tag="BV401_27070"
     CDS             complement(4864..5427)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS27025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BV401_27070"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_141729442.1"
                     /transl_table=11
                     /translation="MPSIKPSELTAEQRSLDAHVRQLMAGLPAPFTSTDPDGALIGPFP
                     VMLRFPGLARPLLEWFTAGTGASVLPARVREVAILTTGSRYAAAYELYSHSRVALDVGL
                     PEDIIEGLVAGQRPAGMTAEETVAHDVAARLHSGAPLPGALYRAVVRAFGDSGTAELVF
                     LVAQYAAISAILNAYDVPLPPDGD"
     gene            complement(5440..6651)
                     /locus_tag="BV401_RS27030"
                     /old_locus_tag="BV401_27075"
     CDS             complement(5440..6651)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058798.1"
                     /locus_tag="BV401_RS27030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27075"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_079258673.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.8e-43, bitscore:
                     145.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIRTVFKNGTVFDGTAAGTADLVIEGRHVVDVGTDLDGDHVVDC
                     AGKSVLPGLFDCHVHVMTRDFNLGRAEQQAFSLQYYEAKRNLSLLLDQGITSARDAAGA
                     DLGVKQAIAQELIEGPRLQIAISMLSQTGGHGDVHLPSGGHRSIPMMTAHPGRPNPIVD
                     GPDGVRRGVREVLRAGADAVKIATTGGVMSPGDNPRHAQFRADELAVIVAEAAAADTYV
                     FAHAQGTEGIKAALRAGVRSIEHGYYLDDEAVDLMLERGAWLVPTLSATRAIIDAADSG
                     IPIPEENANLAREAVEAHQASFALAVQAGVKIAMGTDSPPYWSPTASNLRELALMVNSS
                     SMSALDAWRATTSSPAELLRFDTAGRLAAGKLADVVVIAGSLSDLDDLRGRVRQVWLDG
                     TQVR"
     misc_feature    6644..6662
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.89"
                     /tool="antismash"
     gene            complement(6663..7112)
                     /locus_tag="BV401_RS27035"
                     /old_locus_tag="BV401_27080"
     CDS             complement(6663..7112)
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015286.4"
                     /locus_tag="BV401_RS27035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27080"
                     /product="serine dehydratase beta chain"
                     /protein_id="WP_079153031.1"
                     /transl_table=11
                     /translation="MTTSTAAVSVFDLFTIGIGPSSSHTVGPMKAAAAFAEDLRRAGTT
                     DSVESVRVEIFGSLAATGHGHGAFTAVLLGSDGAQSARIDSGEVERRPADITASGTVSR
                     GAGQRIPCRIEDLVLRPLTVRPRHTNALTLTAYGHAGVACAVEHS"
     misc_feature    complement(7115..7134)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 25.23"
                     /tool="antismash"
     gene            complement(7164..8219)
                     /locus_tag="BV401_RS27040"
                     /old_locus_tag="BV401_27085"
     CDS             complement(7164..8219)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024796.4"
                     /locus_tag="BV401_RS27040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27085"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_069864915.1"
                     /transl_table=11
                     /translation="MSHLDESRQDYDLDELDRRLIHALQINPRARWAALAPIIGVDAVT
                     LARRWERIVEAGIAWVSGHPGPELRGPSAILEIEAHPAATLGLAQEISADSEAFTVDLT
                     AGGREMLVLVATSSMDALTEYLMMRIPKLDGIRATRAHLFTSPFVHGGQWRLRSLSAEE
                     IAAVERSIEVSRSPRGRVDSQLEDQLLRLLGADGRATVAYLARTVGVGQRRVRDAVAAM
                     TAQGRLDTRLDMAKAQSGRPVHAWYFLRVPAALVQRVGSVLTRISEIRLAVSTVGQYNL
                     ILAVWLPTLAGVQRLEAVLEEKLPGVSIADRCVVLRTVKKEGHRLNAHGHATGEFSPLL
                     TNMPQPSPSFE"
     misc_feature    8200..8220
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            8554..9399
                     /locus_tag="BV401_RS27045"
                     /old_locus_tag="BV401_27090"
     CDS             8554..9399
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (29-243). E-value: 1.1e-25. Score:
                     82.3. Matches aSDomain: nrpspksdomains_BV401_RS27045_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012596.4"
                     /locus_tag="BV401_RS27045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27090"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_069864913.1"
                     /transl_table=11
                     /translation="MSDPRWEGHVPPTAFEEYSEKYAGFFKMRRENGIIELRLHTDGGP
                     YIHNWAAHNAWNRVWQDVGNDPDNHVLILTGTGETWFRGDPEETWPRPIVDEEPDYIFQ
                     QTIDAWKLIENFVNNLDIPTIAAVNGPGIHTEFALLCDVTLAAEDADFMDPHFMAGTAP
                     GDGLSLALQHLMGTKRAAYDIYSGRSIPARKALDYGLVSDVLPREELLPKAWAIAGEIM
                     KRPRFARWATHNIVSRPWRKLVAEDFGFHFSQQMLATVAAKRQVPDPDLVTEARSRKVW
                     "
     aSDomain        8641..9282
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS27045_ECH.1"
                     /evalue="1.10E-25"
                     /label="BV401_RS27045_ECH.1"
                     /locus_tag="BV401_RS27045"
                     /protein_end="243"
                     /protein_start="29"
                     /score="82.3"
                     /tool="antismash"
                     /translation="RENGIIELRLHTDGGPYIHNWAAHNAWNRVWQDVGNDPDNHVLIL
                     TGTGETWFRGDPEETWPRPIVDEEPDYIFQQTIDAWKLIENFVNNLDIPTIAAVNGPGI
                     HTEFALLCDVTLAAEDADFMDPHFMAGTAPGDGLSLALQHLMGTKRAAYDIYSGRSIPA
                     RKALDYGLVSDVLPREELLPKAWAIAGEIMKRPRFARWATHNIVSRPWRKL"
     gene            complement(9458..9871)
                     /locus_tag="BV401_RS44980"
     CDS             complement(9458..9871)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019121.4"
                     /locus_tag="BV401_RS44980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_237287833.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 8.2e-07,
                     bitscore: 27.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIIDLILTDDGKPYVLEVNGTPGMSRDSNFAVGATMAGLTHTDV
                     VLAMLHEALARPPRVCATAKSAAAPAIRSSSSVRSCAADALARASSSRASWAFRVVTAS
                     SRRANSRPALIDSLFTGARLKPTRHPTTPRGDQ"
     gene            9861..10127
                     /locus_tag="BV401_RS43995"
     CDS             9861..10127
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS43995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_193524995.1"
                     /transl_table=11
                     /translation="MITITADTYTTRPPEADLAIAEAAARLVPRVRAASDDTVSGVEPE
                     SDGTERSGPEVVPDDADPLGELFGRSTPRALTQTAPNAESEAE"
     misc_feature    10059..10061
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            complement(10172..10247)
                     /anticodon=(pos:complement(6629796..6629798),aa:Arg,
                     seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="BV401_RS27055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="BV401_27105"
                     /product="tRNA-Arg"
     gene            complement(10172..10247)
                     /locus_tag="BV401_RS27055"
                     /old_locus_tag="BV401_27105"
     gene            complement(10511..11149)
                     /locus_tag="BV401_RS27060"
                     /old_locus_tag="BV401_27110"
     CDS             complement(10511..11149)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562242.1"
                     /locus_tag="BV401_RS27060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27110"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_237287834.1"
                     /transl_table=11
                     /translation="MNMNAEHDSPATVETRLTHEAHRLATSLLVDASPRPSVPHQALAR
                     LRDFLVVNLRHHHDAQDEWLWPHIAAAAPEAKPALDDLTEEHKHLDITLTRLADIDLDS
                     QNHRQVLHEAAVAVRDSVHDHLTHEEPVLFPALREHITPWQWKKLSRRVIATTPPAAGH
                     LMIGLLDEVATPAELRSILANMPPPVKARLPAIRTQAATDLQALRTNSP"
     misc_feature    complement(11136..11147)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            complement(11278..11892)
                     /locus_tag="BV401_RS27065"
                     /old_locus_tag="BV401_27115"
     CDS             complement(11278..11892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061141.1"
                     /locus_tag="BV401_RS27065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27115"
                     /product="ABC transporter permease"
                     /protein_id="WP_079258675.1"
                     /transl_table=11
                     /translation="MPLATAVAQATVPATTTAVTRSPGDVDNSAVYVSFGLAYLFGHGS
                     AALSKGTSPLLDLPGWLPMALLGAGLAVGTVQATLAALRAQRGATGPDVLSGKLLGASW
                     IAGFTALFLAITGLASAVDTPDLQDMLWPTGSGIVVGLLYLAEGAVRRNLLHYTLGVWL
                     ALTSAAALFLGTPGLYWVLTIAGGGAYAIATVLERRRHATR"
     gene            complement(12041..13087)
                     /locus_tag="BV401_RS27070"
                     /old_locus_tag="BV401_27120"
     CDS             complement(12041..13087)
                     /NRPS_PKS="Domain: PKS_ER (25-344). E-value: 6.7e-40.
                     Score: 129.1. Matches aSDomain:
                     nrpspksdomains_BV401_RS27070_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044517.1"
                     /locus_tag="BV401_RS27070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27120"
                     /product="medium chain dehydrogenase/reductase family
                     protein"
                     /protein_id="WP_079258676.1"
                     /sec_met_domain="ADH_N (E-value: 2.3e-07, bitscore: 29.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.2e-21, bitscore:
                     73.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSVTTLVTEIVLPGRVEPSGLETRTRDLPAPGAGQVLLRMDAT
                     GVCFAEQQMRLGKYYNQPPFPFVPGYDVVGTITATGPDVDAGMTGRRFAAVTKVGAWAS
                     HLLIDAADLMPVPDDDMDAATVETVVVNGITAWQMLHRTAKVRSGGTIVVLGANGGVGS
                     ILVQLARHAGITVIGTASARHHDSVRELGATPVDYRDPEMYDRIREIAPDGVDAVFDHV
                     GGPAVAESWRLLRRGGTLVSYGTAATKNEEGSSQLPVLKLFGQLAAWNSLPNGKSAHFY
                     NFWAGRRCRTQWQRRLTEDLTQVLRLVADGVLTPRIAAEIPLSDTASALELAESRTVLG
                     KVVIIPDA"
     aSDomain        complement(12056..13012)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS27070_PKS_ER.1"
                     /evalue="6.70E-40"
                     /label="BV401_RS27070_PKS_ER.1"
                     /locus_tag="BV401_RS27070"
                     /protein_end="344"
                     /protein_start="25"
                     /score="129.1"
                     /tool="antismash"
                     /translation="RTRDLPAPGAGQVLLRMDATGVCFAEQQMRLGKYYNQPPFPFVPG
                     YDVVGTITATGPDVDAGMTGRRFAAVTKVGAWASHLLIDAADLMPVPDDDMDAATVETV
                     VVNGITAWQMLHRTAKVRSGGTIVVLGANGGVGSILVQLARHAGITVIGTASARHHDSV
                     RELGATPVDYRDPEMYDRIREIAPDGVDAVFDHVGGPAVAESWRLLRRGGTLVSYGTAA
                     TKNEEGSSQLPVLKLFGQLAAWNSLPNGKSAHFYNFWAGRRCRTQWQRRLTEDLTQVLR
                     LVADGVLTPRIAAEIPLSDTASALELAESRTVLGKVVI"
     gene            complement(13318..13977)
                     /locus_tag="BV401_RS27075"
                     /old_locus_tag="BV401_27125"
     CDS             complement(13318..13977)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061139.1"
                     /locus_tag="BV401_RS27075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27125"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_079258677.1"
                     /transl_table=11
                     /translation="MKESSAADPAAPKRARVRNRRGEGGRLREDIISAAAELLDETGDE
                     RAITLRSVARKVGIAAPSIYPHFPDQPSIMLAVVQREFAELATHLHSEVRAAGDDPREG
                     LYALCRAYLAYAKNHPERYRTMFGGLWMPTLGDNSLTEEDLTSLGSTAIQVLVDALAKC
                     AAAGQSAVTDPPQDAITLWLGLHGLAHQRAVSRTFPWPEESITEAMITRLACLKET"
     gene            complement(14001..15803)
                     /locus_tag="BV401_RS27080"
                     /old_locus_tag="BV401_27130"
     CDS             complement(14001..15803)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009715603.1"
                     /locus_tag="BV401_RS27080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27130"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_079258678.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.8e-78, bitscore:
                     261.7, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPRDAVAHLTPELWDRAGRLLIRKALAEFTHERLLAPEPGPAGR
                     YAVTSDDEAVTYRFAARVLSLDHWLVEADSITRHDRTGAELPLDALDFFIELRGRLGLS
                     ADVLPVYLEEISSTLSGTAFKLAAEPVGAAQLAKSGFQEIETGMTEGHPCFVANNGRLG
                     FGIHEYLSYAPETASPVQLIWLAARRDRSTFTASADIDYDTLIHSELSEPTRARFARTL
                     NDLGLDPADYHLLPVHPWQWWNKLSISFAAEVARQHLVCLGPGDDEYLAQQSIRTFFNT
                     TDPSKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLAALISADEIFRAARFSIIRER
                     AAIGYHHRQYEAATAKGSPYRKMLAALWRESPVPSLEPGQRLATMASLLHTDPDGVSFV
                     SALVEESGLTPATWLRRYLDAYLTPVLHSFYAYDLVFMPHGENVILVIEDGAVQRVIFK
                     DIAEEIAVMDPTAVLPPTVERIRVDVPEDKKLLSIFTDVFDCFLRFLNGILVSEGLLEE
                     DTFWRTVADCVLDYQRAVPHLSDKFAQYDMFAEDFALSCLNRLQLRDNREMVDLQDPAG
                     ALQLIGTLKNPIAEFGAENKGSRH"
     gene            complement(15800..16399)
                     /locus_tag="BV401_RS27085"
                     /old_locus_tag="BV401_27135"
     CDS             complement(15800..16399)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054339.1"
                     /locus_tag="BV401_RS27085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27135"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_079258679.1"
                     /transl_table=11
                     /translation="MTPSPVFEHTDARLGTFALRALDPAADAALLYGWVTHPKASFWMM
                     QGADEAEVAAEYRRIHEHPHHEAFIGLHEGRPAFLAERYDPAVVELAGLYPARPGDVGM
                     HFLCAPTDTPVHGFTLAVLTTVMEFCFADPAVRRVVVEPDVCNAGVHALNAAVGFEIVE
                     QIVKPEKDAYLSICTRERFRAARTALAARAAQGVTR"
     gene            complement(16396..17703)
                     /locus_tag="BV401_RS27090"
                     /old_locus_tag="BV401_27140"
     CDS             complement(16396..17703)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009715601.1"
                     /locus_tag="BV401_RS27090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27140"
                     /product="SidA/IucD/PvdA family monooxygenase"
                     /protein_id="WP_237287836.1"
                     /transl_table=11
                     /translation="MPTPHTFDFIAVGLGPYNLGLACLTEPIDELDGLFLERKPDFDWH
                     PGMLLDGVTLQTPFLADLVTLADPTSPYSFLSYLKESGRLYSFYIREIFYPLRAEYSDY
                     CRWAAAKLPSIRFGHEVTSVEYDEADGVYTVRALRRATGETTTHRARRLVLGTGTPPYL
                     PEVCHGLGGDLLHNTDYLANKRALRSKESITIVGSGQSAAEIYQDLLADVDSCGYRLNW
                     VTRSPRFFPLEYTKLTLEMTSPEYVDYFHALPEDTRYRLEGEQKGLFKGIDAELINGIF
                     DLLYQKSVSGPVPTRLLTNTALTDAAYDEPSGTYTLGLRHEEQKRDFSLTTHGLILATG
                     YRYQVPAFLDPVRDRIRWDRHGRFDVARNYSVDTTGRGIFLQNGATHAHSLTSPDLGMG
                     PYRNSWIIRELLGREHYPVEKSIAFQEFGAPEGAVS"
     gene            complement(17730..19328)
                     /locus_tag="BV401_RS27095"
                     /old_locus_tag="BV401_27145"
     CDS             complement(17730..19328)
                     /NRPS_PKS="Domain: Aminotran_5 (168-301). E-value: 1.3e-07.
                     Score: 22.8. Matches aSDomain:
                     nrpspksdomains_BV401_RS27095_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054341.1"
                     /locus_tag="BV401_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27145"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_079258681.1"
                     /transl_table=11
                     /translation="MSFLAQTAEDPSPEPIPGAADGRTHLFNGRTAERYRRSVTDGVGL
                     VASTVARAERPFTGITPAELAPEISGIDLERPLGDPDAALDELECVYLKDAVYFHHPRY
                     LAHLNCPVVIPALLGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTAERIGLGQAADGI
                     FTSGGTQSNLQAMLLARDEACTLVEKEAAAAGGTIAKSAILPRLRILTSQVSHFSIQKA
                     AAILGLGYEAVIPVPCDQDRRMRTVALAHELDRCRREGLIVMAVVATAGTTDFGSIDPL
                     PEIAELCARHGSWLHVDAAYGCGLLVSPTRRHLLDGIERADSVTVDYHKSFFQPVSSSA
                     VLVRDRATLSHATYHADYLNPERSARKLIPNQVDKSIQTTRRFDALKLWLTLRIMGADA
                     VGALFDEVVERAAEAWALLDTDPRYEVVTEPQLSTLVFRYVPPSDGPCDGPCDPDLVDR
                     ANLHAREALAASGAAVVAGTVVDGRHHLKFTLLNPETSLSDIAFVLDLLAEHAGQYLAL
                     HIEPELSGPRRSRAS"
     aSDomain        complement(18426..18824)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS27095_Aminotran_5.1"
                     /evalue="1.30E-07"
                     /label="BV401_RS27095_Aminotran_5.1"
                     /locus_tag="BV401_RS27095"
                     /protein_end="301"
                     /protein_start="168"
                     /score="22.8"
                     /tool="antismash"
                     /translation="TQSNLQAMLLARDEACTLVEKEAAAAGGTIAKSAILPRLRILTSQ
                     VSHFSIQKAAAILGLGYEAVIPVPCDQDRRMRTVALAHELDRCRREGLIVMAVVATAGT
                     TDFGSIDPLPEIAELCARHGSWLHVDAAY"
     gene            complement(19743..20642)
                     /locus_tag="BV401_RS27100"
                     /old_locus_tag="BV401_27150"
     CDS             complement(19743..20642)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009715599.1"
                     /locus_tag="BV401_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27150"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_079258682.1"
                     /transl_table=11
                     /translation="MTTAATPTAATPTATTTAPFRFFDARVVRTRALGPSMARITFGGS
                     CLKDFISGGRDQRFKLFLPHPGQTAPVVPVEAGEGWFATWRAMDPAERGIMRSYTVRGQ
                     RRDPHEVDVDFALHHDGGPAARWAARAEAGDRVTLLGPAVEDNGGVDFRPPSGTDWVLI
                     AGDETALPAIAGILEWLPADLPTKVWLEVQHAEDIQELRTEAKAEITWLVRDGVAPGTP
                     RSAPLLDTVGAAELPSGTPYAWIAGEAGTVKALRRHLVRERGFDRKAVIFTGYWRLGAC
                     EEQLVEEAVSGTGPAADD"
     gene            complement(20705..21730)
                     /locus_tag="BV401_RS27105"
                     /old_locus_tag="BV401_27155"
     CDS             complement(20705..21730)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054343.1"
                     /locus_tag="BV401_RS27105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27155"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_079258683.1"
                     /transl_table=11
                     /translation="MRQARALPLSRRGLLAAGGAVGLGALVTACGDNGGSGSGGDDGGG
                     SWSFTDDRKTKISLDSRPQHIVAYIGAAAALYDFGIDKQITGVFGPTTLKNGKPDVQAG
                     DFPVGQATSLGNTWGQFNVEKYASLGPDLLITNMYDPGALFYVPDDSKKKILQLAPSAA
                     ITTGRISMLEPIKRYAALAEALGADLKAKKVTDAKARFEKAAETLRKTVKSHKIKVMAC
                     SASADLFYVSNPKISADLIYFSELGVDFVVPEKTDKGGYFESLSWENADKYDADVLFLD
                     NRTATLQPSALTAKPTWSKLAAVKAGQITPWSSEPRFSYAGAAPLVESLTKAIQDAKKV
                     G"
     misc_feature    complement(21792..21810)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 29.02"
                     /tool="antismash"
     gene            complement(22001..22264)
                     /locus_tag="BV401_RS42445"
                     /old_locus_tag="BV401_27160"
     CDS             complement(22001..22264)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS42445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BV401_27160"
                     /product="hypothetical protein"
                     /protein_id="WP_079258684.1"
                     /transl_table=11
                     /translation="MSGAPTAEVYRIDWLPGTDVLHGVCHCGAERTAEDPVELWEWMLG
                     HPNGHRAGGSRPGTEHDPADHRPADRRPADHRPAGHRKETTS"
     gene            complement(22261..23322)
                     /locus_tag="BV401_RS27115"
                     /old_locus_tag="BV401_27165"
     CDS             complement(22261..23322)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054346.1"
                     /locus_tag="BV401_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27165"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_079260618.1"
                     /transl_table=11
                     /translation="MTAFARNQWYVAAYGREIGRELLGRTILDEPIAFYRAESDDTVIA
                     LANRCVHRRYPLTAGRLDGDTVVCGYHGFTYDTGGACVFVPGQKRVPRTARVRSYPVVE
                     QDSLVWVWIGDPALADPGAVPRAPWLADPGWTTVGGMEPIDSDYGLLVDNLLDLSHETY
                     LHSGYIGTPEVAETPITTEVDEGAGVVRVSRHMDDAECPPFYARSTGIEGRITRWQDIE
                     YHAPCLYLLHSRIAPVGVLPEPDGSDPDAFHVEITYAITPSTDRHVYDFWAVSRDFAQD
                     DEEVSTFLHDLNRTVVLQDVGALNLLQQALDTEREGYQELSINIDTGGLAARRILARLA
                     AEGERAAAVVASP"
     misc_feature    23335..23350
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            complement(23439..23717)
                     /locus_tag="BV401_RS27120"
                     /old_locus_tag="BV401_27170"
     CDS             complement(23439..23717)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048469.1"
                     /locus_tag="BV401_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27170"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_079258685.1"
                     /transl_table=11
                     /translation="MALTAPSRTAPLRARGDADGMAVASFVLGLIGLLLFNAVFGPCAI
                     VLGTLALARETRRRGRALLGIALGIADVVLLIVLLTLNHSVFWQFGG"
     gene            complement(23723..23878)
                     /locus_tag="BV401_RS43600"
     CDS             complement(23723..23878)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179033.1"
                     /locus_tag="BV401_RS43600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_014054348.1"
                     /transl_table=11
                     /translation="MLFIVAALALMGVLLGAAAHTPLPLFLAAAGAIGAWLLIFFIRER
                     TGHKGS"
     misc_feature    complement(23864..23879)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.8"
                     /tool="antismash"
     misc_feature    complement(24058..24072)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.79"
                     /tool="antismash"
     gene            24073..24807
                     /locus_tag="BV401_RS27125"
                     /old_locus_tag="BV401_27175"
     CDS             24073..24807
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179034.1"
                     /locus_tag="BV401_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27175"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_079258686.1"
                     /transl_table=11
                     /translation="MSHRCGVRQAQKEKTRRALLDAALRLLEDQSLSSLGLREVTRAVG
                     VAPAAFYRHFRDLSDLGVALVEESLGSLHHMIGAILAGQDGDAERIDATVAAVADHVRR
                     YPAHIRFIARERHGGVRAVREAIAAELDRFADEVATDFCPRLSAEDWPPEDVRMLAELY
                     VDHMVMTATAFLEAQAEHPGAAGASGAADVEGAVGPAGAVGAAGAEDAAGAAGAEDERR
                     VAATARKQLLLISLGRHHWRDG"
     gene            complement(24773..26104)
                     /locus_tag="BV401_RS27130"
                     /old_locus_tag="BV401_27180"
     CDS             complement(24773..26104)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054350.1"
                     /locus_tag="BV401_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27180"
                     /product="M6 family metalloprotease domain-containing
                     protein"
                     /protein_id="WP_079258687.1"
                     /transl_table=11
                     /translation="MEQTHGTTRPRIRIRRPRRGSAFATAAVLTVAVVSPGAAARPEPP
                     APPELAPAPSARPAFGSLAPCALASGPGLQMSEGLPTSRGYSHSTGTVHALNLMIDFPD
                     VRGQGTARERFEEFFPQTTRWFTQSSYGRLDYRPEMPITHWLRMPRSFRAYGIKRGSPF
                     DPGYRKLVADIAKAADPKVDFRRYDLVNVLVTPNAGPPAAHAVLSVTYADNQQAPTADG
                     VPLANVSFVYSRQDDGSGSLRRTGFRVLPHENGHVFGLPDLYTRLGGDKAGHWDVMSED
                     WGAGNDLLAWHKWKLGWLDPRQIACAARSGVVAHTLSPLSRPEGTKLVFVPVSPSTGYA
                     IEARANGGNDEAICKPGVLISWVDTGVDSGGGPITIVDSTPHGRGCTRERNVHPGLSDA
                     AYGPGESFSTQANGTRIRVRVTGRDADGDYGVEISRRASGGARG"
     misc_feature    complement(26205..26220)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    26403..26423
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.04"
                     /tool="antismash"
     gene            26405..27055
                     /locus_tag="BV401_RS27135"
                     /old_locus_tag="BV401_27185"
     CDS             26405..27055
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054351.1"
                     /locus_tag="BV401_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27185"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_069864860.1"
                     /transl_table=11
                     /translation="MAADTMTAKSAQPRLRADALRNRERIVVAAREVIVESGAHIPLDE
                     IARRAGVGNATIYRHFTDRRELIHHVALSVMSHVADQAETAMAEEVDAFSALRRFVHAA
                     ADERIGALCLLLSDGLDKEHPDLIATRDRLSEGVEALMGAAKADGQLRTDIGVGDLMVA
                     LNQLTRPLPGSFCVDFDAFVHRHLQLFLDGLRAPARSELPGKSVTLEDLQHRP"
     gene            27238..28746
                     /locus_tag="BV401_RS27140"
                     /old_locus_tag="BV401_27190"
     CDS             27238..28746
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054352.1"
                     /locus_tag="BV401_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27190"
                     /product="MFS transporter"
                     /protein_id="WP_069864858.1"
                     /transl_table=11
                     /translation="MPETAQYVDPRRWKALIFIALAQLMVVLDATIVNIALPSAQADLG
                     ISDGNRQWVITAYALAFGGLLLFGGRIADLWGRKQTFIVGLLGFAAASAIGGAALNTGM
                     LLGARALQGVFGALLAPSALSLLAVMFTDPKERAKAFGVFGAIAGGGGAVGLILGGVLT
                     EYMDWRWTFFVNIPFAIIAVVGAVAVIREPVESRNSSRLDIPGVILATTGLVALVYGFT
                     RAESDGWTAGLTVGLFIAAAVLLLAFVIVESRVKAPLLPLRVVADRNRGGVYASLALAI
                     IGMFGLFLFLTYYMQIVKGYSPVKTGFAFLPMVAGMITGSTQIGARLMTRVPARRLMGP
                     GFLVASVGMLLLTQIDLDTSYPMLILPGFLLLGLGMGTAFMPAMSLATHGVEPRDAGVA
                     SAMVNTSQQVGGAIGTALLNTIAASATTEYAKSHAAGATSRKALELQSMVHGYTSAIWW
                     AVGILVLAAVIAITLVNAGQPENGGAVAGSGDGAAEDAIPVMAH"
     gene            complement(28907..29407)
                     /locus_tag="BV401_RS27145"
                     /old_locus_tag="BV401_27195"
     CDS             complement(28907..29407)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017945679.1"
                     /locus_tag="BV401_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_27195"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_069865586.1"
                     /transl_table=11
                     /translation="MKTLTDTDEPRWLTDDEQRSWQAYIQASMLLEDHLDRQLQRDARM
                     PHVYYGLLVKLSWAPRHRMRMTELAESAKITRSRLSHAIARMEKDGWVRREDCPDDKRG
                     QNAVLTDKGFEVLREAAPGHVSAVRLAVFDRLSPEQVEQFGDICRIIADGLQPEGADLP
                     WLR"
     misc_feature    complement(29433..29450)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.55"
                     /tool="antismash"
ORIGIN
        1 gaaggtgaac acccacggcc acggtggcgg ctgctcgttc tggatggcgt cggtgctgcg
       61 ggccgcttgg tcgagcgcgg cttccgcggc tggacgatcc cccgcggccg cgtgcgcgag
      121 cgcctcgacc gtcccgagcc acgcggtggc gatggccggt ggcgcgtcgc ccagctgacg
      181 atgggcattg cgcacgaggg cgagcccctg gggcgcgttc ccggcgtctg cctcgaatcc
      241 ggccaggctg ccgagctggt aggcgaggag cagtcggtca ccggaggtac gcgcggcctt
      301 gatggacgcg ccgtaccagg tgcgcgccga tccgatgtcg ttcatgtccc aggccagcca
      361 accggccagg gacgccgctt cgctgcccac cgcggccaag cgggctcgct gctcgggcgt
      421 ttcggcgtcg cctgtgatgg tctgggtgag ccgcaagtgg gccaggaccg gctcggaaag
      481 ctgccgggag ggggtgttgc cgtccagccg ccggaaagcc gtggtggcca ctcgcagaga
      541 cgcggcctgg cccgtgtccg cgggcttggg cgtacgggtt gccagggcgg gcgcggcggc
      601 tatcgctgcg gttcccgcga ggaagttgcg ccgatacacg tcgtactgcc cattctcggc
      661 gacatgcgcc gccgcgtggt cggcgaggcc aaccagacgc gggggaatgc gcaggtgcgc
      721 ggcggctctc gccaggatgg tcatgtcgta tgaggctgtg ccgcgtcctt cgagacgaga
      781 gacagcggac tgactgatcc cgcaggcgtc gccaagttgg ttttgggaga caccggcgtc
      841 gcggcgggcc aggctgacga cccgcccgta gtcaccgtga cgggcggcgt cccgaatcgc
      901 ctgcgaagac cagttcatat ccactcccgt tggtacccgg gtctccccgt ttgcctgcca
      961 cgggtatgcg ccggccgcat acccgtatgc gcgtcgcggg tcagcgctgg tcgatacagc
     1021 atgacgcacg gtttcgtctc ctcactaccc gtaatcggga aggggacgca tgagtaccga
     1081 gaccttgctg tggacaccgc cgaacactga ggacgtcgag gcgttaccgg tcggcagatg
     1141 gtgggacgcc gtccgcgcgg ccccgaccgt cggcgaacgc gccctcggtc tgctcggcga
     1201 cgagaccgga gccgtgatcc aggacaagca cggccccctg tactggctca tcgccgtggg
     1261 ctccgctacg agttggcacc tgcggcaggt ccgagtcctc accgagctga ccgacgcgag
     1321 cacctacctc ggcgtcccgc ccgccgcctg gacgaagggc cccaggaccc actggcgcgt
     1381 gccgctctcg gccgaccact acctgaccga tgcccggcgc ctgtgggagg cgctggccga
     1441 ggcggaccgc gccgagtacg ggcgcatgcc ggaaggacgc caactctgcc accgctgcca
     1501 tctgcccacc gacgagccga tcccggtcga ggcggaggac acccgcggcg ccgtcggcaa
     1561 ggccacgtac gcctgccccg cccacgcgct ccacccgaag ccccagcacc cgcggacccc
     1621 caccaacgcg gccgcggccg agcacgaggg gcgccgatga agaagagcca cgaggcggac
     1681 atcgcacgac cggggcccgc cggaatcaac ccggacacgc tgacctacca acagctccag
     1741 ggctggaact gcgccttatg cgggcggccg ctgggcgcgg accgccctct cggcgctgag
     1801 cggcccctcg gcgtggatcg gccgctgggc acggaccgtc cgctgggcac ggtcacgatc
     1861 gagcgagacg cgacgcggac gacctacgag gtgcgcgcct gtgctccctc ctgtgcggag
     1921 acctccaccg gcccggccgc cgagaccgaa tggcgcgagg ccatcgagca cgccgcgggc
     1981 tgcccggcct gccggacgcc cggcgccggg tgcgagaccg gggagcgtct gctgcacacc
     2041 tacgaggagg ccgcgcggca ggccaggtca ggggagggca tatgagacac cgtacggcgg
     2101 ccaaccgccg cacgtgccgg gccgctcgcc ttccgcaccg cccgcatggg cctgatgaat
     2161 cgaccgcata cgttacggca gtggacgatg aagtggttca actcgttcgg cgtcttggtt
     2221 ccttcaatgc gagcggtccg gcgccctggt tgtgctgttc ggggaggtga gcttgtcccc
     2281 gaggatgtcg gcgagcaggt cgatctgttt cgggtcggtg tggttgccca cgaagacgag
     2341 ttcgtcgagt ccggctgttt cgtgggtggt gacggttgtg tggatcatgt cggcggtggt
     2401 ggccgctgtg tcgatgacgg tccggacgta gtcggggccg gcgaaggcgt agtagtcgtt
     2461 gacggcgcgg gtgagggatt ggtgtgcgtg gccgccgagg gcgaacatcg ccgtggccct
     2521 ggtgcgcgga cgtccttgcc tgccggcctc tttccagtgg ctgtggaggc gggtggcgaa
     2581 ggtggtgaac tcgtcgatgt ctccgccggt tccggcgatc catccggtgc cgtgggaggt
     2641 gatacgccgc agcgttgcct gcgatgtgcc gccgaaccac agtggtggcc ctgcgggggt
     2701 ggccggggcc ggacccacct cttcttcacc ccgccagatg gcggtgacgc gttccacgag
     2761 tgtgtccagg gcgcgccctc gggtgctgaa gtccaggtgg cttgcctggt agtcgtcttc
     2821 gcgggctccg ggagcgaggc cgagatggag ccgtccggcg cccgcgatcc ggtccaaggt
     2881 cgccgcggcc ttggcgaaca gtgcggggtt ggtgtgcagc ggggccagca gcacgctggt
     2941 gaccagccgg atgcgttcgg tggccccggc tgccgcggcc agtgtgatca ggggttccgg
     3001 agtggaccag gccaggcggt cgctggcggt cagcgaggcg aatccccgct cctcagcccg
     3061 ccgcgcccat gtcaccagcg tacgttcctc aaggccggtg acatgacccg gcagccctac
     3121 gcctatctcc atgtgccgtg tctcttcctt cggtaacgga ccgggtggtg ggtgtccttc
     3181 cgccgctgcc ggctgtgctt cgtcggcagc ggcggaaggc gttgtccgcc cggcctcgtg
     3241 acgtgcgtcg gggtattttc agttttcggt ggctcagttt ttgagtgtgc cgccgtactc
     3301 ctccgggacg aggtcggcct gctcggcgcc gctcctgatc agatcgagga tggtgtcggc
     3361 ggcgccctcg ggcgactggg gtgccaggcc gctggagtcc tccattttga gcgcgcctgc
     3421 gacgtcgccg cggaccgtcc tgacgaactc ggtctcggtg atcgagggga acatcatcga
     3481 cacggtgatg ttgtcgtcgg cgagctcggc gcgggcgatg gccgagagct tggcgagggc
     3541 ggctttggag gcggagtatg cgccggatcc gggcagcgag gaccagatga tcccggagcc
     3601 cacgttcacg atggcgccgg ctccctgctt gcgcatctgc ggaaggacgg cctgcgtcgt
     3661 ggtcaggggt gcgaggaggt tgagttcgag gacggcccgg aagtcctcgg ggtcgatggc
     3721 gtcgacggtc gcttgtagcc cctggcctgc gttgttcacc aggatgtcga tccgcccgaa
     3781 cttctcgatc gcggcttcta cggccgccgt gacctggacc cggtccgtca catcgcatgg
     3841 cacggccagg gccacggact cgccgagttc ccctgcgagc tgtcggatgc gttcctcgcg
     3901 gcgggcgagg agcaccacgc gcgcaccggc gcgggaggcg gcgcgtgcgg tggcccctcc
     3961 gatgcctgac gacgctccgg tcacgagtac tacggctccg ctgatgtcca taggggattc
     4021 ctcatccatg cgtcggtgga ttgcctgagc agcgccacgg cgttcgaggc gcgggggcgt
     4081 ccgccatcca atactatcgc ttgatagcta tcaagcgata ggaaggtatc ctcatggcat
     4141 gagcgacgtc aacgccgcca gtctccacga gctggccgac ctggtcttcg ccgtggggcg
     4201 gcagcttcgg cccccggcgg accccgcctt cgagccgtgc acgccgatcg agatcagcgt
     4261 catgcggttc atccaccacc accccggcac gtccgcgcga gccgcgtcgg aggcgaccct
     4321 gcttccgtcg agcaacttca gccgggtact gcgcggcctg gagaagaggg ggctcgtgga
     4381 gcgcgtcgtg gacgaccgca acgcccgagg cgtgcgcctg taccccactg acaaggccca
     4441 ccggaatcac cagatcctcc gcgacaactg ggaccggacc ctccggggca tcatcgacga
     4501 ccccgccacc atcgagatcg tcaatgccac gctccggcgt atcgaggatg aactcatagc
     4561 ccggcgcagc gggacggact ccgatcgcga tcaaaccgac cagcctcggg ctttcgcgcg
     4621 cccagcggac tggaggtctt gatgttgtaa gtgatctttg gtcgtaagct cgttgtcgcc
     4681 tgccggtggg agtccggtcc gggtagctgc caggaggccc ggtagtggac tggcggtgtc
     4741 ggggggaagc gcccggggcc gaagcccagt gtcgaaagcc ctgtttcggg gcgggggcgg
     4801 ggagtgccga gcccccgaaa tcagggcgaa ggccatggaa gcggcgaacg tcctgacgca
     4861 gggtcagtcg ccgtcgggcg gcagtggcac gtcgtacgca ttgaggatcg ccgagatggc
     4921 ggcatactgc gcgacgagga agacgagttc agccgtaccg gagtcgccga aggcgcggac
     4981 gacggctcgg taaagcgctc ccggcaaagg cgcgccgctg tgcagccggg cagccacatc
     5041 gtgagcgacc gtttcctcgg cggtcatgcc tgccgggcgc tgccccgcga ccaggccctc
     5101 gatgatgtcc tccggcagac cgacgtcgag cgcgacccgg gagtgcgagt acagctcgta
     5161 ggccgcggca taccgcgacc ccgtggtgag aatcgcaacc tcgcgcaccc gggcgggcag
     5221 gactgaggca ccggtgccgg ccgtgaacca ctccagcagc gggcgggcga gcccgggaaa
     5281 gcggagcatc accgggaacg ggccgatcag cgcgccgtcg ggatcagtcg aggtaaacgg
     5341 cgcgggcaac ccggccatga gctgtcggac gtgagcgtcg agcgagcgct gctcggctgt
     5401 cagttcgctg ggcttgatcg agggcatgcg cacaacgcat caccgtacct gcgtgccgtc
     5461 gagccacacc tgacggaccc ggccgcgaag gtcgtcgaga tcggacagac tgcccgcgat
     5521 gacgaccaca tccgcgagct tgccggctgc caaccttccg gcggtgtcga atcgaaggag
     5581 ttcggccggg ctcgacgtcg tggcgcgcca ggcatccagc gcggacatcg acgaggagtt
     5641 caccatcaga gcgagttctc tgaggttgct cgctgtcggg ctccagtagg gcgggctgtc
     5701 ggtccccatg gcgatcttca ctcccgcctg gacggcgagt gcgaagctcg cctgatgagc
     5761 ttcgacggcc tcacgggcaa ggttggcgtt ctcttccggg atcggtatgc cgctgtcagc
     5821 ggcgtcaatg atggcgcgtg ttgctgacag cgtgggaacg agccaggcgc cacgctcgag
     5881 catgaggtcg actgcttcgt cgtccaggta gtagccgtgt tcgatggaac ggacgccggc
     5941 ccgcaaggct gccttgattc cctcggttcc ctgcgcgtga gcgaatacgt aggtgtcggc
     6001 cgcggcggct tcggcgacga tcaccgctag ctcatcggcg cgaaactggg cgtggcgggg
     6061 attatcgcct ggagacatga ctccgccggt ggtggcgatc ttgactgcgt cggctcccgc
     6121 gcgcaggact tcacgaactc ctcgccgtac tccgtccggg ccgtcgacga tcgggttggg
     6181 ccgtccgggg tgtgccgtca tcatcgggat cgatcgatga cctcccgagg ggagatggac
     6241 atcgccgtgc ccgcccgttt gggacagcat cgagatcgcg atctgaagtc gtggcccctc
     6301 gatgagttcc tgtgcgatcg cttgcttcac ccctaggtct gcgcctgcgg catctcgggc
     6361 agaggtgatg ccttggtcga gcaggagcga caggttgcgc tttgcttcgt aatactgcaa
     6421 ggagaaggct tgttgttcgg cgcgtccgag gttgaagtct cgggtcatca cgtgcacgtg
     6481 gcagtcgaac agcccgggga ggaccgactt tccagcgcag tccacaacgt gatcaccgtc
     6541 cagatcggtc ccgacatcga cgacgtggcg gccttcgatg acgaggtcgg ctgtgcctgc
     6601 tgcggttccg tcgaagacgg tcccattctt gaagactgtg cggattgcca ttgctcctca
     6661 tttcatgaat gttcgactgc gcaggcaacg ccggcatggc cgtatgccgt gagcgtcaac
     6721 gcgttcgtgt ggcgcggccg tacggtcaac ggtcgcagca cgaggtcctc gatccggcag
     6781 gggattcgtt gccctgcgcc gcggctcacc gtgccggatg ccgtgatgtc cgccggtctt
     6841 cgctcaactt cgccggagtc gatcctggct gattgcgcac catccgagcc gagaagcacc
     6901 gcggtgaacg cgccgtgccc gtgtccggtc gcggcgagcg agccaaatat ctccactcgc
     6961 actgattcga cgctgtccgt cgtgcccgct cgtcgtaggt cctccgcaaa ggcggcggct
     7021 gccttcatcg gtccgactgt gtgcgaactt gagggcccaa tcccgatagt gaacaggtcg
     7081 aagacactga cagcagctgt cgaagtggtc atgaagcggg acggtagtcc gcgcgtgcaa
     7141 tgggcccggc ctgttgcagg atttcactcg aaagacgggc ttggctgagg catattggtc
     7201 agcagagggc tgaattcgcc ggtggcgtgc ccatgggcat tgaggcggtg tccttccttc
     7261 ttgaccgtgc gcagcacgac gcaacggtcg gcgatgctga cgccgggaag tttctcctcg
     7321 aggacggcct cgagccgctg cacgccggcc agcgtcggca accacacggc gaggatgagg
     7381 ttgtactgtc cgacagttga aaccgcgagg cggatctcgc tgatacgtgt gagcaccgac
     7441 ccgacgcgct gcacgagcgc ggcagggaca cggaggaagt accacgcatg aaccggccgg
     7501 cctgattgcg cttttgccat atccaggcgg gtgtccaacc gcccttgtgc agtcatggcc
     7561 gcaaccgcat cccgtacccg acgttggccc acgccgacgg tcctcgccag gtaagccact
     7621 gtcgccctgc catccgcacc caggaggcga aggagttggt cctccagctg agagtcgacg
     7681 cggcccctcg gggatcgcga gacctcgatg ctccgctcta ccgcagcgat ctcctcggct
     7741 gacagggagc gaagacgcca ctgacctccg tgcacgaagg gtgacgtgaa caagtgggcc
     7801 cgggtcgccc gaatgccgtc aagtttcggt atccgcatca tcaaatactc cgtgagggca
     7861 tccatgctgg atgtggccac cagcacgagc atctcgcgcc ccccggccgt gaggtccacc
     7921 gtgaacgctt cactgtccgc cgagatctcc tgtgcgagac ccagcgtggc ggcagggtgg
     7981 gcttcgattt ccagtatggc cgacggccct ctcagctccg ggccgggatg tccggacacc
     8041 catgcgatgc cagcctcgac gatgcgttcc cagcgccggg cgagggtgac cgcgtcgacc
     8101 ccgataatcg gcgccagcgc agcccagcgt gctcgcgggt tgatctggag ggcatggatg
     8161 agccgccgat cgagctcatc gaggtcgtag tcctgccgac tctcgtccaa atgactcata
     8221 agacttgact ctatgttacg ggaaaaggtt gatgtttcgg tgggtatgcg gttgttcaag
     8281 tgcggtgtgc cgaagcatcc cgacgtggct ccgtgcggag attccagacg ccgcaactcg
     8341 cgatgccctt tgaggtgcag agtggagctc gtgacgccga ccgaattgcg gcagaagggc
     8401 gcgcctgtct gccgtcaaac ttcatcgcgg tcggcttctg gggatttttc ctgcgttgcc
     8461 ggtcatgccg cttcctcgtg gagtaatgat cttcgcatta gtgcgagagc gtcgctatcc
     8521 cggcgctgac gaaggaggac gaccttggcg accatgtcag acccccggtg ggaaggccac
     8581 gttccaccga ccgcatttga ggagtactca gagaagtacg ccggtttctt caagatgcgc
     8641 agggagaacg ggatcatcga gcttcggctc cacaccgacg gcggtccgta catccacaac
     8701 tgggccgccc acaacgcgtg gaaccgggtg tggcaggacg tgggcaacga ccccgacaac
     8761 catgtcctca tcctgaccgg caccggcgag acctggttcc gaggcgaccc cgaggagacg
     8821 tggccgcggc ccatcgtcga cgaggagccc gactacatct ttcagcagac catcgatgcg
     8881 tggaagctga tcgagaactt cgtcaacaac ctcgacatcc cgacgatcgc ggcggtaaac
     8941 ggtcccggga tccacaccga gttcgcgcta ctctgcgacg tcactttggc cgcggaagac
     9001 gcagacttca tggacccgca cttcatggcg ggcaccgcgc cgggagacgg actctcgctc
     9061 gccctacagc acctgatggg cacgaagcgg gcggcctacg acatctacag tggccgctcc
     9121 atccccgcgc ggaaagcact cgactacggg ctcgtcagcg acgtacttcc gcgtgaggag
     9181 ctcctgccga aggcgtgggc gatcgcaggc gagatcatga agcgcccgcg gttcgctcgc
     9241 tgggcaaccc acaacatcgt gtctcgcccc tggcgcaagc tcgttgccga agacttcggt
     9301 ttccacttct cgcaacagat gcttgccacc gtcgccgcca agcgacaggt tcccgacccc
     9361 gacctggtca ccgaggcgcg ctcacgcaaa gtgtggtgag aacctgaggg acgaagcagg
     9421 ttgtcggccg ccgtcacgga cggcggccga cacctgtcta ctgatctcct cggggtgttg
     9481 tcggatggcg agtcggtttc aggcgagcgc cggtgaacaa gctgtcgatc agagcgggac
     9541 gactgttcgc gcgcctggac gaggccgtca cgacccggaa tgcccagctg gcccgagaac
     9601 tgctggcccg cgccaacgcg tccgccgcgc acgaccgcac cgaggacgag gaccggatcg
     9661 cgggcgccgc cgccgacttc gcggtcgcgc agacccgtgg cgggcgggcc agggcctcgt
     9721 gcagcatcgc caagacgaca tccgtgtgcg tgagcccggc catcgtcgcc cctaccgcga
     9781 agttgctgtc acgggacatg cccggcgtgc cgttgacttc cagcacgtac ggcttgccgt
     9841 catcggtgag gatcaagtcg atgatcacca tcacggccga cacgtatacg acccggcctc
     9901 ccgaggcgga tctggcgatc gccgaggccg ctgcccggct cgtgccgcgt gtacgtgccg
     9961 cctccgacga caccgtttcc ggcgtggagc cggagtcgga cggtacggag aggtctggcc
    10021 cggaggtcgt gccggatgat gctgatccgt tgggagagtt attcgggaga tcaactcccc
    10081 gtgcgctcac gcaaacggcc ccgaacgcgg agtccgaggc cgaataaggc gcctccctgg
    10141 gggagaaatc ccaggtcagc ggcgtaacgc atggtgcccc cggcaggatt cgaacctgcg
    10201 acacccgctt taggagagcg gtgctctatc ccctgagcta cggaggctgg ggactgggtt
    10261 gggagtgtgg tgggaagctc ggcggtgaat ggtgatcatc ggccgggctc cgcacggatc
    10321 cgtccggtcc ctggtggtcg ctggtgtggc ggccagaggt cagcctaccg ggttcgggat
    10381 ccgggtgtgg aaccggttgc cggcgttgtg ctgtcgtggt gggcggcggg cgtctgtatc
    10441 cgggcgcggg cggcgccggg ggccgtgtgc aggtggtgtc gggggtctgt gtgcgggggt
    10501 gccgggtgag tcatgggctg ttggttcgga gggcttgcag gtcggtggcg gcttgggtgc
    10561 ggatggcggg tagccgggcc ttcaccgggg gtggcatgtt cgcgaggatc gagcggagct
    10621 cggccggtgt ggccacctcg tcgaggagtc cgatcatcag gtgtccggcc gccggagggg
    10681 tcgtggcgat gactcgtcgg gagagcttct tccactgcca cggtgtgatg tgctcccgca
    10741 aggcggggaa caggaccggc tcttcgtggg tcaggtggtc atgcacgctg tcgcgtacgg
    10801 ctacggctgc ctcgtgtagc acctggcggt ggttctggct gtcaaggtcg atgtcggcga
    10861 ggcgggtgag tgtgatgtcc aggtgtttgt gttcctcggt caagtcgtcg agtgcgggct
    10921 tcgcctccgg tgccgctgcc gcgatatgcg gccacagcca ttcgtcctgg gcgtcgtggt
    10981 ggtgacgcag gttcaccacg aggaagtccc gcaatcgcgc gagcgcttgg tgaggtacgg
    11041 aggggcgggg gctggcgtcg acgagcaggc tggtggcgag tctgtgtgcc tcgtgggtga
    11101 ggcgcgtttc cacggtggcc ggtgagtcgt gctcggcgtt catgttcatc ggccgggggt
    11161 cagaccgcgc tgctgccggt gtgggaggcc aggccggaca ccagcttcgc gagctcgggg
    11221 tcggcctcgt agtttcgctt gatcatggat tctcctgtgg tgggtgaagg cgagtggtca
    11281 gcgggtggcg tggcggcggc gttcgagcac cgtggcgatg gcgtacgcgc cgccgccggc
    11341 gatggtgagg acccagtaga ggcccggggt gccgaggaag agcgcggcgg cggaggtcag
    11401 ggcgagccag acgccgaggg tgtagtggag caggttgcgg cgtacggcgc cttcggcgag
    11461 gtagagcagg ccgacgacga tgccggagcc ggtgggccag agcatgtctt gcagatcagg
    11521 tgtgtcgacg gcggaggcca ggccggtgat cgcgaggaac agggcggtga agccggcgat
    11581 ccaggacgcg ccgagcagct ttccggacag gacgtccggg ccggtggcgc cgcgctgggc
    11641 gcgtagggcg gcgagcgtcg cctggacggt gccgaccgcc aatccggcgc cgaggagcgc
    11701 catgggcagc cagccgggca ggtcgaggag ggggctggtg cccttggaga gcgcggcgga
    11761 gccgtggccg aagaggtagg cgagcccgaa gctgacgtag accgcgctgt tgtcgacgtc
    11821 gcccggtgag cgcgtcacag cggtggtggt ggcggggacg gtggcctggg cgacggcggt
    11881 ggcgaggggc atgacgggac ctccggagtg atggggtggg tggggtgtgt ggtggtgtgc
    11941 gggatcgttg ggtggtttaa ccgccgtgcg ccgtacgaag gttctggtgg ccgggacgaa
    12001 gcgctgttcg ggcgttcggg acgaagtgcc ccgcgggcct tcacgcgtcc ggaatgatga
    12061 cgaccttgcc caggacggtg cgggactcgg cgagttccag tgccgaggcg gtgtcggaca
    12121 gcgggatctc ggcggcgatc cgcggcgtga ggacgccgtc ggccaccagg cgcagcacct
    12181 gggtgaggtc ctcggtcagc cggcgctgcc actgcgtccg gcagcggcgg cctgcccaga
    12241 agttgtagaa gtgcgcgctc ttgccgttgg gcagcgagtt ccatgcggcg agttgcccga
    12301 agagcttcag cacgggcagt tgtgagctgc cctcttcgtt cttcgtcgcc gcggtgccgt
    12361 acgagacgag ggttccgccc cggcgcagca ggcgccagga ctccgccacc gcggggccgc
    12421 cgacgtggtc gaagaccgcg tccacgccgt ccggcgcgat ctcccggatg cggtcgtaca
    12481 tctccgggtc gcggtagtcg accggggtcg cgcccagttc gcgcacgctg tcgtggtgcc
    12541 gcgcggaagc cgtgccgatc accgtgatcc cggcgtgccg ggccagctgg acgaggatgg
    12601 agccgacgcc gccgttggcg cccagcacca cgatggtccc gcccgagcgc accttggccg
    12661 tccggtgcag catctgccag gcggtgatcc cgttgacgac cacggtctcc acggtggccg
    12721 cgtccatgtc gtcgtccggc accggcatca gatccgcggc gtcgatgagc agatggctgg
    12781 cccaggcgcc gaccttggtg accgcggcga atcggcgtcc ggtcatcccg gcgtccacgt
    12841 ccggtcccgt cgcggtgatg gtgcccacga cgtcgtatcc ggggacgaag gggaagggcg
    12901 gctggttgta gtacttgccg aggcgcatct gctgttcggc gaagcagacc ccggtggcgt
    12961 ccattcgcag aaggacctgg cccgcgccgg gggcggggag gtcgcgggtc cgggtctcca
    13021 ggccactcgg ctcgaccctg ccgggcagga cgatctcggt gacgagggtg gtgaccgacg
    13081 tgctcatgga gggctccttg aagcctcggc tgtgtgctta cgggcgtaag gctacgcagg
    13141 taagtcgaga cgaggcaagg ggctacggca ataaacttat ggctgtaagg ttacgtggcg
    13201 aaaggcgccc ttcgtttcgg cgcggccggg gctgccgtgc cgggacgaag ggcgccttcg
    13261 gtgttcctcg aggccggtcc tggggcgttg tcgcattgcc tcggggcggc gatgtggtca
    13321 ggtctccttg aggcaggcca gtctggtgat catggcctcg gtgatgctct cctccggcca
    13381 ggggaacgtg cggctgacgg cgcgctggtg cgcgaggccg tgcaggccga gccagagcgt
    13441 gatcgcgtcc tgcggtgggt cggtgaccgc ggactggccc gcggcggcgc acttcgcgag
    13501 agcgtcgacg agcacctgga tggccgtcga gccgaggctg gtgaggtcct cctcggtcag
    13561 ggagttgtcg cccagggttg gcatccagag gccgccgaac atcgtgcggt agcgctccgg
    13621 gtggttcttg gcgtaggcga ggtaggcccg gcagagggcg tacagccctt cccgtgggtc
    13681 gtcgccggcc gcccgcacct cggagtgcag atgggttgcc agttcggcga actcccgctg
    13741 tacgacggcc agcatgatgg acggctggtc tgggaagtgc gggtagatcg acggggcggc
    13801 gatgccgacc ttgcgggcga ccgaccgcag ggtgatggcg cgttcgtcgc cggtctcgtc
    13861 gaggagttcc gcggccgcgg agatgatgtc ctcgcgcaga cggccacctt cgcctcgacg
    13921 gttgcgtacg cgtgcccgtt ttggtgcggc cgggtctgcc gcgctgctct ccttcacccc
    13981 gtaacgttac atcgcgaagt ttagtggcgc gatcccttgt tttccgctcc gaactccgcg
    14041 atcgggttct tgagggtgcc gatgagctgg agcgcgcccg cggggtcctg gaggtcgacc
    14101 atctcgcggt tgtcgcggag ctggaggcgg ttgaggcagg agagggcgaa gtcctcggcg
    14161 aacatgtcgt actgggcgaa tttgtccgag aggtggggga cggcccgctg gtagtccagg
    14221 acgcagtcgg cgaccgtccg ccagaaggtg tcctcctcca acaggccctc actgaccagg
    14281 atgccgttga ggaagcgcag gaagcagtcg aagacgtcgg tgaagatcga gagcagcttc
    14341 ttgtcctcgg ggacgtccac gcggatgcgt tccaccgtcg gcgggaggac cgccgtgggg
    14401 tccatgacgg cgatctcctc ggcgatgtcc ttgaagatca cgcgttggac ggcgccgtcc
    14461 tcgatcacca ggatgacgtt ctcgccgtgc ggcatgaaga ccaggtcgta ggcgtagaag
    14521 ctgtgcagca ccggggtgag gtaggcgtcc aggtagcggc gcagccaggt cgcgggggtg
    14581 aggccggatt cctcgacgag ggcgctgacg aaggagacgc cgtcggggtc ggtgtggagg
    14641 agggacgcca tggtggccag gcgctgaccg ggctccaggg acggtacggg gctctcgcgc
    14701 cacagcgcgg cgagcatttt gcggtacggg gagcccttcg cggtggcggc ctcgtactgg
    14761 cggtggtggt agccgatggc ggcccgctcc cggatgatcg agaagcgggc ggcgcggaag
    14821 atctcgtcgg cggagatcag ggcggccagc cagtcgttga tggccggggt cgcctccata
    14881 taggcggcgg acaggccccg catgaagccc atgttgagga ccgacagcgc ggttttcaca
    14941 tagtgcttgg acgggtcggt ggtgttgaag aaggtgcgga tcgactgctg ggcgaggtac
    15001 tcgtcgtcgc cggggccgag gcacaccaga tgctgccggg cgacctcggc ggcgaagctg
    15061 atcgacagct tgttccacca ctgccagggg tgcaccggca gcaggtggta gtcggcgggg
    15121 tccagaccga ggtcgttgag ggtcctggcg aagcgggccc gggtcggctc gctcagttcg
    15181 gagtggatca gggtgtcgta gtcgatgtcc gcggaggcgg tgaaggtgga gcggtcgcgg
    15241 cgggcggcga gccagatcag ctggacgggg ctcgcggtct cgggggcgta cgagaggtat
    15301 tcgtggatgc cgaagccgag gcggccgttg ttggcgacga agcaagggtg gccctcggtc
    15361 atccccgttt cgatctcctg gaagccggat ttggccagct gggcggcgcc caccggctcg
    15421 gcggccagtt tgaaggccgt accggagagg gtggagctga tctcctcgag gtagacgggg
    15481 aggacgtccg cgctcaggcc gagccgtccg cgcagctcga tgaagaagtc cagtgcgtcg
    15541 agggggagtt cggcgccggt ccggtcgtgg cgggtgatgc tgtcggcctc gaccagccag
    15601 tggtccaggg agagcacccg ggcggcgaac cggtaggtca ccgcctcgtc gtcgctggtc
    15661 acggcgtagc ggccggcggg gcccggctcg ggggcgagca ggcgctcatg tgtgaactcg
    15721 gcgagggcct tgcggatgag gaggcggccc gcccggtccc acagttcggg ggtgaggtgg
    15781 gcgacggcgt cgcgggggct catcgggtca ctccttgggc ggcgcgggcg gcgagggcgg
    15841 tgcgggcggc ccggaaccgc tcgcgggtgc agatgctgag gtaggcgtcc ttctcgggtt
    15901 tgacgatctg ctcgacgatc tcgaagccga cggccgcgtt gagcgcgtgc acccccgcat
    15961 tgcacacatc gggctcgacg accacgcgcc gtacggccgg atcggcgaag cagaactcca
    16021 tgacggtggt gagcacggcc agggtgaagc cgtgcaccgg ggtgtcggtc ggcgcgcaga
    16081 ggaagtgcat gccgacgtcg ccgggccggg ccgggtagag accggcgagt tccaccaccg
    16141 ccgggtcgta gcgctcggcg aggaatgccg ggcgtccctc gtgcagaccg atgaacgcct
    16201 cgtggtgcgg atgttcgtgg atcctgcggt actcggcggc gacctccgcc tcgtccgccc
    16261 cctgcatcat ccagaaggac gccttggggt gggtcaccca gccgtacagc agcgcggcgt
    16321 cggccgccgg gtccagggcg cgcagggcga aggtgcccag gcgcgcgtcc gtgtgctcga
    16381 aaaccggcga aggcgtcatg acacggctcc ttccggtgcg ccgaactcct ggaaggcgat
    16441 ggacttctcc accggatagt gctcgcggcc cagcagctca cggatgatcc acgagttgcg
    16501 gtacgggccc atgcccaggt cgggggaggt caggctgtgg gcgtgggtgg cgccgttctg
    16561 gaggaagatg ccgcgtccgg tggtgtcgac gctgtagttg cgggcgacgt cgaagcggcc
    16621 gtggcggtcc cagcggatgc ggtcgcgtac ggggtccagg aaggcgggca cctggtagcg
    16681 gtagccggtg gccaggatga gcccatgggt ggtgagcgag aagtcccgct tctgctcctc
    16741 atggcgcagc ccgagggtgt aggtgccgga cggctcgtcg tacgccgcgt cggtgagcgc
    16801 ggtgttggtc agcagccgcg tgggcaccgg gccgctcacg ctcttctggt acaggaggtc
    16861 gaagatgccg ttgatgagct cggcgtcgat ccccttgaac aggcccttct gctcaccctc
    16921 cagccggtag cgggtgtcct cggggagcgc gtggaagtag tccacgtact cgggcgaggt
    16981 catctccagg gtgagtttgg tgtactccag cgggaagaag cgcggggagc gggtcaccca
    17041 gttcagccgg tagccacagg agtcgacgtc ggcgagcaga tcctggtaga tctcggccgc
    17101 gctctggccg ctgccgacga tggtgatgga ctccttcgat cgcagcgccc gcttgttcgc
    17161 caggtagtcc gtgttgtgca gcagatcgcc gcccaggccg tggcacacct cggggaggta
    17221 cggcggggtg ccggtgccca gcaccagacg gcgggcgcgg tgggtggtgg tctcgccggt
    17281 ggcgcgccgc agcgcgcgca ccgtgtagac cccgtcggcc tcgtcgtact cgacgctcgt
    17341 cacctcgtgg ccgaagcgga tggacggcag cttcgcggcg gcccagcggc agtagtcgct
    17401 gtactcggcg cgcagcggat agaagatctc gcggatgtag aaggagtaca gccgccccga
    17461 ttccttgagg tagctgagga aggagtacgg ggaggtgggg tcggccagcg tcaccaggtc
    17521 ggccaggaac ggggtctgga gggtgacgcc gtccagcagc atgcccggat gccagtcgaa
    17581 gtcgggcttg cgctccagga acagtccgtc gagttcgtcg atcggctcgg tgaggcaggc
    17641 aaggcccagg ttgtaggggc cgagcccgac cgcgatgaag tcaaaggtgt gcggggtggg
    17701 cacgtggatc tccggcggga cgaagggact caactggcgc gcgagcggcg ggggccgctg
    17761 agctcgggct cgatgtggag ggcgaggtac tgaccggcgt gctcggccag gagatcgagg
    17821 acgaacgcga tgtcgctcag cgaggtctcc gggttgagca gggtgaactt gaggtggtgc
    17881 cggccgtcca cgacggttcc ggcgacgacc gccgcgccgg aggcggccag tgcctcgcgg
    17941 gcgtgcagat tggcgcggtc caccaggtcc gggtcgcacg gcccgtcgca cggcccgtcg
    18001 gacggcggta cgtagcggaa gaccagcgtg gacagctggg gctcggtgac gacctcgtag
    18061 cgcggatcgg tgtccagcag ggcccatgcc tcggcggccc gttccaccac ctcgtcgaag
    18121 agcgccccga ccgcgtccgc gcccatgatc cgcagcgtca gccacagctt gagcgcgtcg
    18181 aagcggcggg tggtctggat ggacttgtcg acctggttgg ggatgagctt tcgggcgctg
    18241 cgctcggggt tgaggtagtc ggcgtggtac gtggcgtggc tgagcgtggc gcggtcgcgg
    18301 accagcacgg cgctggagct gaccggctgg aagaaggact tgtggtagtc cacggtgacc
    18361 gagtcggcgc gctcgatgcc gtcgaggagg tggcggcggg tcggggagac cagcagtccg
    18421 cagccgtacg cggcgtccac atgcagccag ctgccgtgcc gggcgcacag ctcggcgatc
    18481 tcgggcagcg ggtcgatgga gccgaagtcg gtggtgcccg cggtggccac gacggccatg
    18541 acgatcaggc cctcgcggcg gcagcggtcc agctcatggg cgagggcgac ggtccgcatc
    18601 cggcggtcct ggtcgcaggg gaccgggatg acggcctcgt agccgagccc caggatggcg
    18661 gcggccttct ggatggagaa gtggctgacc tgggaggtga gaatgcgcag ccgcggcagg
    18721 atcgcggatt tggcgatcgt cccgccggcc gcggcggcct ccttctccac gagcgtgcac
    18781 gcctcgtcgc gggccagcag catcgcctgg aggttggact gggtgccgcc gctggtgaag
    18841 atgccgtccg cggcctggcc gaggccgatg cgctcggcgg tccagtcgat cagccggcgc
    18901 tcgatcaggg tgccgccggc actctggtcc caggtgtcga gggaggagtt gacggcggag
    18961 aggacggcct cgcccagcag tgcggggatc accacggggc agttgaggtg tgcgaggtag
    19021 cgcgggtggt ggaagtagac ggcgtccttg agatagacgc actccagctc atcgagcgcg
    19081 gcgtccgggt cgccgagcgg ccgctccagg tcgattccgg agatctcggg ggcgagttcg
    19141 gcgggggtga taccggtgaa ggggcgctcc gcgcgggcga cggtggaggc caccaggccg
    19201 acgccgtcgg tgacggagcg ccgatagcgt tccgcggtac ggccgttgaa gaggtgggtc
    19261 ctgccatccg ccgccccggg tatcggctcc ggcgacgggt cctcagcggt ctgcgcgagg
    19321 aaactcacgg tctgtccctt ctgggaatga gcatgcgggc gtgcggatgg cgcgggcatg
    19381 cgactggtgg ggagggcgga ccgcggcctg accggcctgg tggacatgcg ggggcgctgg
    19441 acgcggcggc cgggcgcgtg ggggcgcgcc gggcggacgg ccgccggtcg tccggcggtc
    19501 ggtcctcgcg gtcctggagg ggatgcggtt atggggattc gattggaggt tcggctgggg
    19561 atgcggttgt gggatttcgg ttgtgggatg tggccatgag gacgcggccg atggaggcgg
    19621 cggccgatgg aggagtggcc aatggggatc cggctatgag gaggcggccg tgaggacccc
    19681 cgctgtgggg acgcggccat gaggatcccc gccgtgagga ggcggtgtgg cggcggggag
    19741 ggtcagtcgt cggccgcggg gccggtgccc gacacggcct cctcgacgag ttgctcctca
    19801 caggcgccca ggcgccagta gccggtgaaa atcacggcct tgcggtcgaa gccgcgttcg
    19861 cgcaccaggt ggcggcgcag cgccttgacg gttccggcct cgcccgcgat ccaggcgtac
    19921 ggcgtgccgg agggcagctc ggcggcgccc acggtgtcca gcagcggggc ggaacgcggg
    19981 gtgccggggg ccacgccgtc ccggaccagc caggtgatct cggctttcgc ctcggtgcgc
    20041 agctcctgga tgtcctcggc gtgctggacc tcgagccaca ccttggtggg caggtcggcg
    20101 ggcagccatt cgaggatgcc cgcgatggcg ggcagcgcgg tctcgtcgcc ggcgatcagc
    20161 acccagtcgg tgccggacgg cggccggaag tcgacaccgc cgttgtcctc cacggccggg
    20221 cccagcaggg tgacgcggtc gccggcctcg gcacgcgcgg cccagcgggc ggccgggccg
    20281 ccgtcgtggt gcagcgcgaa gtccacgtcg acctcatggg ggtcgcggcg ctgcccgcgc
    20341 accgtgtacg agcgcatgat gccgcgttcg gccgggtcca tcgcccgcca ggtggcgaac
    20401 cagccctccc cggcctcgac cggcaccacc ggggcggtct ggccgggatg cggcaggaac
    20461 agtttgaagc gctggtcgcg gcctccgctg atgaagtcct tcagacagct gccgccgaag
    20521 gtgatccgtg ccatggacgg tcccagcgcg cgggtccgta cgacccgcgc gtcgaagaag
    20581 cggaacggag cggtggtggt ggcggtgggg gtggctgcgg tgggggtggc tgcggtggtc
    20641 atgggaggag ggtcttccct tcgcttgccg tggggagggc cgggccggcc ggtcggccga
    20701 ccgttcagcc gaccttcttc gcgtcctgga tggccttggt gagggactcg acgagcgggg
    20761 cggcgcccgc gtacgagaag cgcggctcac tgctccaggg ggtgatctga ccggccttga
    20821 ccgcggccag cttggaccag gtcggcttgg cggtcagggc gctgggctgg agggtcgcgg
    20881 tgcggttgtc gaggaagagc acatcggcgt cgtacttgtc ggcgttctcc cagctgaggc
    20941 tctcgaagta gccgcccttg tcggtctttt ccgggacgac gaagtcgacg ccgagctcgc
    21001 tgaagtagat caggtcggca ctgatcttcg ggttggagac atagaagaga tcggcgctgg
    21061 cggagcaggc catgaccttg atcttgtgtg acttgaccgt tttgcgcagc gtttcggccg
    21121 ccttctcgaa ccgcgccttg gcgtcggtga ccttcttggc cttcagatcg gcgccgagcg
    21181 cctcggccag cgcggcatag cgcttgatgg gctcgagcat ggagatccgg ccggtggtga
    21241 tggcggcgct gggggccagc tggagaatct tcttcttgct gtcgtccggg acgtagaaga
    21301 gcgcgcccgg gtcgtacatg ttggtgatca gcagatcggg gccgagcgag gcgtacttct
    21361 cgacgttgaa ctgcccccag gtgttgccca gggaggtggc ctggccgacg gggaagtcgc
    21421 ccgcctggac gtccggcttg ccgttcttca gcgtggtcgg gccgaagaca ccggtgatct
    21481 gcttgtcgat gccgaagtcg tagagcgcgg ccgccgcgcc gatgtaggcg acgatgtgct
    21541 ggggtcggct gtcgaggctg atcttcgtct tgcggtcatc ggtgaacgac caggagccgc
    21601 cgccgtcgtc gccaccggag cccgaaccgc cgttgtcgcc acaggcggtg accagggctc
    21661 cgagtccgac ggcgccgccc gcggcgagca gaccgcggcg ggagaggggg agtgctctgg
    21721 cctggcgcat gaaggtgctc tctctcgatg cattacgggg acgtggtcgg gacggcaacc
    21781 cgaggacgta gttaggttag cctaaccaac ctgtttgtcc agtgggcggg gtcgttccga
    21841 acctcacatc gaggggcaca aagggcggtt cagcgcggat tcacaggtcc ggcaccgtgc
    21901 aaccgggcgg agccgccgcg cccggcggat tcgcggagca ccgcgagtcc gccgggaggc
    21961 gtggtcggcg ggatcggggc acggcgagtg ccgccggggt tcacgaagtg gtctccttcc
    22021 ggtggccggc gggacggtgg tcggcagggc ggcgatcggc ggggcggtgg tcggcgggat
    22081 cgtgttcggt gccgggccga ctcccgccgg cccggtgccc gttgggatgg ccgagcatcc
    22141 actcccacag ctcgaccggg tcctcggcgg tgcgctcggc cccgcagtgg cagaccccgt
    22201 gcagcacatc ggtgccgggc agccagtcga tccggtacac ctcggccgtg ggcgcgccgc
    22261 tcatggggag gccaccacgg ccgcggcccg ctctccttcg gcggcgaggc gggcgaggat
    22321 gcggcgcgcg gccagaccgc cggtgtcgat gttgatgctg agctcctgat agccctcgcg
    22381 ctcggtgtcc agggcctgct gaagcaggtt cagcgccccc acgtcctgga gcaccacggt
    22441 ccggttgagg tcgtggagga aggtggacac ctcctcgtcg tcctgtgcga agtcccgtga
    22501 gacggcccag aagtcgtaca catggcggtc ggtggacggg gtgatggcgt aggtgatctc
    22561 cacatggaag gcgtccgggt cggagccgtc cggctccggc agtaccccca ccggggcgat
    22621 cctgctgtgc agcagataca gacacggcgc gtggtactcg atgtcctgcc agcgggtgat
    22681 gcggccctcg atcccggtgg agcgggcgta gaagggcggg cactcggcgt cgtccatatg
    22741 gcggctgacg cgtacgacac ccgcgccctc gtcgacctcc gtggtgatcg gggtctcggc
    22801 gacctcgggg gtgccgatgt agccgctgtg cagataggtc tcgtgggaga ggtccagcag
    22861 attgtccacg agcaggccgt agtcggagtc gatcggctcc atgccgccca ccgtggtcca
    22921 gccagggtcg gccagccagg gagcgcgcgg caccgcgccg ggatcggcga gcgccgggtc
    22981 cccgatccac acccacacca gcgagtcctg ctcgacgacg gggtaggagc ggacccgggc
    23041 ggtgcgcgga acgcgcttct ggcccggtac gaacacacag gcgccgccgg tgtcataggt
    23101 gaagccgtgg tagccgcaga cgacggtgtc gccgtcgaga cggccggcgg tgagcggata
    23161 gcggcggtgc acacagcggt tcgcgagcgc gatgaccgtg tcgtcggact ccgcgcggta
    23221 gaaggcgatg ggctcgtcga ggatggtgcg ccccagcagc tcccggccga tctcgcggcc
    23281 gtaggcggcg acgtaccact ggtttctggc gaaggcggtc atgcgtgcca gcgtggtgac
    23341 gcacatcacg tatgggcaac ggcccttcca ctgagtggaa gagccgcccg ctgagcggaa
    23401 gggccgcgcg ggagggggcc cggtggactg ccggcgggtc agccgccgaa ctgccagaag
    23461 acggagtgat tcagcgtcag caacacgatg agcaggacca catcggcgat gccgagcgcg
    23521 atgccgagca gcgcccggcc cctgcggcgg gtctcccggg cgagtgcgag cgtccccagg
    23581 acgatcgcgc agggcccgaa gaccgcgttg aagagcagca ggccgatcag gccgagcacg
    23641 aaggaggcga cggccatgcc gtcggcgtcc ccgcgggccc ggaggggtgc ggtgcgggac
    23701 ggtgcggtga gtgccatggg tctcagctcc ccttgtgccc ggtgcgttcg cggatgaaga
    23761 agatgagcag ccaggcgccg atggcgcccg cggcggcgag gaacagaggg agcggggtgt
    23821 gcgccgccgc ccccagaaga acccccatca gggcgagtgc cgcgacgatg aagagcattt
    23881 gagcctcttt cgaagtgacg atccggatgc ggttggcgtg cgggtggtgt tgtccggttg
    23941 gaccttgttc gcttgggcgt ggttcgcccg agtgttgttc ggtgaacagt tggaagtaca
    24001 actgttcact gagattcaga gtaccccgcc ggggcctgga aaacttcagc gaacagctgt
    24061 ttactgaatg atatgagtca caggtgcggg gtccggcagg cccagaagga gaagacccgg
    24121 cgcgccctgc tggacgcggc attgcggctg ctggaggacc agagcctgag cagtctgggg
    24181 ctgcgtgagg tcacgcgggc ggtgggcgtg gcgccggccg ccttctaccg gcacttccgg
    24241 gatctgagcg atctcggcgt cgcgctggtc gaggagtccc tgggcagtct gcaccatatg
    24301 atcggcgcga tactcgccgg tcaggacggt gacgcggagc ggatcgacgc caccgtcgcc
    24361 gcggtcgccg accatgtgcg ccgctacccc gcgcatatcc gcttcatcgc gcgtgagcgg
    24421 catggcgggg tgcgtgccgt acgcgaggcc atcgccgccg agctggaccg attcgccgat
    24481 gaggtggcca ccgacttctg cccgcggctc tcggccgagg actggccgcc ggaagacgtc
    24541 cggatgctcg cggagctgta tgtggaccac atggtgatga cggcgacggc gttcctggag
    24601 gcgcaggcgg agcaccccgg ggccgcgggt gcttcgggtg ccgctgatgt cgagggtgcc
    24661 gtgggccccg ctggtgccgt gggcgccgct ggcgccgagg acgccgctgg tgccgcgggc
    24721 gccgaggacg agcgccgggt cgccgccacc gcgcgcaaac aactgctgct gatcagcctc
    24781 gggcgccacc actggcgcga cggctgatct ccacgccgta gtcgccgtcc gcgtcccggc
    24841 cggtgacgcg gacccgtatc cgggtgccgt tcgcctgcgt gctgaagctc tcgccgggcc
    24901 cgtaggccgc gtcgctgagt ccggggtgga cattgcgctc ccgggtgcag ccgcggccgt
    24961 ggggggtgga gtccacgatg gtgatggggc cgccgccgga gtcgacaccg gtgtccaccc
    25021 aggagatcag gacaccgggc ttgcatatgg cctcgtcgtt gccgccgttc gcgcgcgcct
    25081 cgatcgcgta gccggtggac ggcgagacgg ggacgaagac cagcttggtc ccctccgggc
    25141 ggctcagcgg ggacagggtg tgcgcgacga ccccggagcg ggcggcgcag gcgatctgcc
    25201 gtgggtcgag ccaccccagc ttccacttgt gccaggccaa caggtcattg ccggcgcccc
    25261 agtcctcgga catcacatcc cagtggcccg ccttgtcgcc gccgagccgg gtatagaggt
    25321 cgggcagccc gaagacatgg ccgttctcat ggggcaggac gcggaagccg gtgcggcgca
    25381 gcgagccgga gccgtcgtcc tggcggctgt agacgaagga gacattggcc agcggaacgc
    25441 cgtcggcggt cggggcctgc tggttgtctg cgtaggtgac ggacagcacc gcgtgtgcgg
    25501 caggcggccc ggcgttcggg gtgaccagga cgttcaccag gtcgtagcgg cggaagtcga
    25561 ccttggggtc ggcggccttg gcgatatcgg cgacgagttt gcgatagccc ggatcgaagg
    25621 ggctgccgcg cttgatgcca taggcgcgga acgagcgcgg catccgcagc cagtgggtga
    25681 tcggcatctc ggggcggtag tccagccgtc cgtacgagct ctgtgtgaac caccgggtgg
    25741 tctgggggaa gaactcctcg aagcgctcgc gggcggtgcc ctggccgcgg acgtccggga
    25801 agtcgatcat gaggttgagg gcgtgtaccg tgccggtgct gtggctgtag ccgcggctgg
    25861 tgggcaggcc ctcggacatc tggagccccg ggccggaggc gagggcgcag ggtgcgagcg
    25921 agccgaaggc cggccgtgcc gaaggcgccg gggccagctc ggggggtgcg gggggctcgg
    25981 gacgcgcggc cgcccccggt gagaccaccg ccaccgtgag cacggcggcg gtggcgaatg
    26041 cgctgcctct gcggggccgg cgtattcgta tgcgggggcg ggtggtccca tgcgtctgct
    26101 ccattgccga ccacggtgtg acggcgtggg ccggggcgct cgtggggtga cgccgtccgg
    26161 gggaatgacc tgctccgttc gggcggcgag gggtgccggg caggtgtgag gcaggtcacc
    26221 tacggacgca gaaattccgg ggactcattc cccgtttaac ccggtgaacg cataaacggg
    26281 gactgactcc ccggaagagt tgaaactcga acgtcaaggc cgaggccggt gtcacagccg
    26341 agccgccggc cgagccaccg gagaaccgta cgcatggatg ccgtacgcag aagggagtgc
    26401 tgttatggcc gccgacacga tgaccgcgaa gtccgcacag cctcggctgc gcgcggacgc
    26461 cctgcgcaat cgggagcgta ttgtcgtagc cgcccgtgag gtgatcgtcg agagcggggc
    26521 acatatcccc ctcgatgaaa tcgctcgacg ggcgggggtc ggcaatgcca cgatctatcg
    26581 gcacttcacg gaccgccgtg agctgatcca ccatgtggcg ctctcggtga tgtcccacgt
    26641 cgccgatcag gccgaaaccg ccatggccga ggaggtcgac gccttctccg cgctgcggcg
    26701 cttcgtacac gccgcggcgg atgagcgcat cggtgcgctg tgcctgctgc tctccgacgg
    26761 tctcgacaag gagcatcctg acctcattgc cacccgtgac cgtctgtccg aaggcgtcga
    26821 ggccctgatg ggggccgcga aagccgacgg ccagctgcgc accgacatcg gcgtcggtga
    26881 tctgatggtc gcgctcaacc agctcacccg gccgctgcca ggcagcttct gtgtggactt
    26941 cgacgccttt gtgcaccggc atctgcaact gttcctggac ggtttgcggg ccccggcgcg
    27001 ctccgaacta cctggtaagt ccgtgacctt ggaggatctg caacaccggc cgtgaccgtg
    27061 acataaatcg catccggccg atcccgaagc accgcttatt ccacgcgcgt tcacaagtct
    27121 tccgtacgtg cgtcgtcgca tctcgctacc tcttatccaa cggcctgtgc cggtctgacc
    27181 ttgaccggcc ccacacgtcc catttgtcac tctccgcacc gctaggtagg accctccatg
    27241 cctgaaacgg ctcaatacgt ggatccccgg cgctggaaag cgctgatatt catcgccctc
    27301 gcccagctga tggttgtgct cgacgcgacc atcgtgaaca tcgcgctgcc cagcgcccag
    27361 gccgatctcg gcatctccga cggcaaccgg cagtgggtca tcacggccta cgccctcgcc
    27421 ttcggcggac tgctgctgtt cggcggccgg atcgccgacc tgtggggccg taagcagacc
    27481 ttcatcgtcg gcctgctcgg cttcgctgcc gcctcggcca tcggcggtgc cgcgctcaac
    27541 accggcatgc tgctgggcgc gcgggcgctc cagggtgtgt tcggcgcact gctcgccccc
    27601 tccgcgctct cgctgctcgc cgtgatgttc accgacccca aggagcgcgc caaggcgttc
    27661 ggtgtcttcg gtgccatcgc gggtggtggc ggcgccgtcg gtctgatcct cggcggtgtc
    27721 ctcaccgagt acatggactg gcgctggacc ttcttcgtga acatcccgtt cgccatcatc
    27781 gccgtggtcg gtgcggtcgc cgtgatccgc gagccggtgg agagccgtaa ctcgtcccgg
    27841 ctggacatcc ccggtgtgat cctggccacc acgggtctgg tcgcactggt ctacggcttc
    27901 acccgcgccg agtccgacgg ctggaccgcg ggcctgaccg tcggtctgtt catcgccgcg
    27961 gccgtgctgc tgctcgcctt cgtgatcgtc gagtcgcggg tgaaggcgcc gctgctgccg
    28021 ctgcgcgtgg tcgccgaccg caaccgcggt ggtgtctacg cctcgctggc actcgccatc
    28081 atcggcatgt tcggactgtt cctcttcctc acctactaca tgcagatcgt caaggggtac
    28141 agcccggtca agaccggctt cgccttcctg ccgatggtcg cgggcatgat caccggctcg
    28201 acgcagatcg gcgcccggct gatgacccgg gtcccggcgc ggcggctgat ggggccgggc
    28261 ttcctggtcg cctcggtcgg catgctgctg ctgacccaga tcgacctgga cacctcgtac
    28321 ccgatgctga tcctgcccgg gttcctgctg ctcggcctcg gcatgggcac cgccttcatg
    28381 ccggcgatga gcctggccac gcatggtgtc gagccgcgtg acgcgggtgt cgcctcggcg
    28441 atggtcaaca cctcgcagca ggtgggcggc gccatcggca ccgcgctcct gaacacgatc
    28501 gcggcgagcg ccaccaccga gtacgcgaag tcgcatgcgg ccggggccac ttcccgcaag
    28561 gcgctggagc tccagtcgat ggtccacggc tacacctccg ctatctggtg ggcggtcggc
    28621 atcctggtgc tggccgcggt gatcgccatc acgctggtca acgccggcca gccggagaac
    28681 ggcggcgcgg tcgcgggctc cggggacggg gcggcggagg acgccatccc ggtgatggcg
    28741 cactgatgcc gatgcgctga ggtgctgatg cgctgaggtg ctgaggtatt cgccggtctg
    28801 tccgtacggc ggcgaaggcc ccgctccctg gaatccaccg gggagcgggg ccttcgtgtg
    28861 ccgtctcggg gtgtcggtgt cggtgtctcg gcgtggtctc agggtgtcag cgcagccagg
    28921 ggaggtcggc gccctccggc tggaggccgt ccgcgatgat ccggcagatg tcgccgaact
    28981 gctcgacctg ctcgggggag agccggtcga agacggccag ccgtacggcg gagacatggc
    29041 cgggggcggc ctcccgcagc acctcgaatc ccttgtcggt gaggaccgcg ttctgccctc
    29101 gcttgtcgtc ggggcagtcc tcgcgccgta cccagccgtc cttctccata cgcgcgatgg
    29161 catgggacag ccgggagcga gtgatcttgg cggactcggc cagttcggtc atccgcatcc
    29221 ggtggcgagg cgcccaggag agcttcacca gcaggccgta gtagacatgg ggcatgcgcg
    29281 cgtcgcgctg gagctggcgg tcgaggtggt cctccagaag catgctcgcc tggatatacg
    29341 cctgccagct gcgctgttcg tcgtcggtga gccaacgcgg ttcgtcggta tccgtgaggg
    29401 ttttcatggc gtcgtccacg cgtccattct agataacact ctttgaacat taaataagtg
    29461 tgcggtacag tgaggactgc atgcttgaga cttcaagcat cttgtcgaat ccagctctgt
    29521 cgaccgccga ggagtcatca tgtccgcgct cgacgggcgc atgcccgccc tttacctcag
    29581 ccatggtgct ccgccgctcg ccgacgatcc ggtctggccc ggacagctcg ccgcctgggc
    29641 cgaggggctg ccccggccca atgccattct catgatctcc gcccactggg aagaggcgcc
    29701 cctggccatc ggggccactc agcaagtgcc gctggtctat gacttctggg gttttcccca
    29761 gcactactac caggtgcggt atgacgcgcc gggcgccccc gag
//
