LOCUS       NZ_CP019458            29060 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces autolyticus strain CGMCC0516 chromosome, complete
            genome.
ACCESSION   NZ_CP019458
VERSION     NZ_CP019458.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces autolyticus
  ORGANISM  Streptomyces autolyticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M., Ren,Z., Dong,Y. and Lu,T.
  TITLE     The complete genome sequence of Streptomyces autolyticus CGMCC 0516,
            the producer of geldanamycin, autolytimycin, reblastatin and
            elaiophylin
  JOURNAL   J Biotechnol 252, 27-31 (2017)
   PUBMED   28472671
REFERENCE   2  (bases 1 to 10029028)
  AUTHORS   Yin,M., Jiang,M. and Lu,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2017) Yunnan University, Yunnan University, 2#
            Cuihu Beilu, Kunming, Yunnan 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 279x
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:05:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,227
            CDSs (total)                      :: 8,141
            Genes (coding)                    :: 7,920
            CDSs (with protein)               :: 7,920
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 74 of 221
            Pseudo Genes (incomplete)         :: 182 of 221
            Pseudo Genes (internal stop)      :: 9 of 221
            Pseudo Genes (multiple problems)  :: 42 of 221
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:31:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 104298
            Orig. end                         :: 133358
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019458.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29060
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..29060
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29060
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:19060]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19060
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            434..1159
                     /locus_tag="BV401_RS00550"
                     /old_locus_tag="BV401_00530"
     CDS             434..1159
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016173.4"
                     /locus_tag="BV401_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00530"
                     /product="Dyp-type peroxidase domain-containing protein"
                     /protein_id="WP_079255646.1"
                     /transl_table=11
                     /translation="MNVQKHTRRRFLTSSAAVTLGAAAVGTAAGTQLPHKGTASAAPSP
                     THHTPSSIPFFGVHQPGIADPTPTNAVFLAFDLKDSTVKSDLADVMRAWTGLAAALMRG
                     DTSADTSLVSTGSTPGKFTMTVGLGGAALDQLDIKRTPALVDLPLFPGDELEVAASHGA
                     VFVQLCSDDAIYLGGAVRAVRAAAKRVLRPRWQMNGFRGAAASTASSNGRNLMGQIDGT
                     NNIAVSRASTGGPVWVDAV"
     misc_feature    477..489
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     misc_feature    1313..1322
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            1633..2085
                     /locus_tag="BV401_RS00560"
                     /old_locus_tag="BV401_00540"
     CDS             1633..2085
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015596.4"
                     /locus_tag="BV401_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00540"
                     /product="hypothetical protein"
                     /protein_id="WP_158525825.1"
                     /transl_table=11
                     /translation="MFSVVIAIGIAATLAGCTAGGSAKVGARTSAIAVLDSKDLGDILV
                     DGKGNVLYAFKPDNASTVSCTFGCATVWPPLSVADNASTAAGDGADVALLSKLPDHAGG
                     HVVTYNGWPLYRYAADKAPGQHRGQDVFLNGGYWYVMKPDGKPLMP"
     misc_feature    complement(1643..1656)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.15"
                     /tool="antismash"
     gene            complement(2454..3146)
                     /locus_tag="BV401_RS00570"
                     /old_locus_tag="BV401_00550"
     CDS             complement(2454..3146)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (4-162). E-value: 9.4e-10. Score:
                     30.6. Matches aSDomain:
                     nrpspksdomains_BV401_RS00570_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059365.1"
                     /locus_tag="BV401_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00550"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_079255649.1"
                     /transl_table=11
                     /translation="MTGKTVLITGATSGIGAHTARLLLDRGHRVAVTGRNESKLKTFLD
                     EAGHPDRLLGLVADAADWQATESVVTRTVEHFGALDAAVANAGFMSGDSIGAGKPTSWA
                     PMVLTNVLGPALLAHATLPHLEATGGRLVLIGSVAGLKNSPANLYSATKWATTGLAENL
                     RLHATTRGIGVTLVNPGMIDTPFWQGASVPPFALPPQPIAEAICFALDQPAGVDLNTLT
                     IRPMGQPV"
     aSDomain        complement(2661..3134)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS00570_PKS_KR.1"
                     /evalue="9.40E-10"
                     /label="BV401_RS00570_PKS_KR.1"
                     /locus_tag="BV401_RS00570"
                     /protein_end="162"
                     /protein_start="4"
                     /score="30.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVLITGATSGIGAHTARLLLDRGHRVAVTGRNESKLKTFLDEAGH
                     PDRLLGLVADAADWQATESVVTRTVEHFGALDAAVANAGFMSGDSIGAGKPTSWAPMVL
                     TNVLGPALLAHATLPHLEATGGRLVLIGSVAGLKNSPANLYSATKWATTGLAEN"
     CDS_motif       complement(3039..3134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS00570_0001"
                     /evalue="3.20E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="BV401_RS00570"
                     /protein_end="36"
                     /protein_start="4"
                     /score="26.2"
                     /tool="antismash"
                     /translation="TVLITGATSGIGAHTARLLLDRGHRVAVTGRN"
     gene            3321..4250
                     /locus_tag="BV401_RS00575"
                     /old_locus_tag="BV401_00555"
     CDS             3321..4250
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191795.1"
                     /locus_tag="BV401_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00555"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_079255650.1"
                     /transl_table=11
                     /translation="MEPPSENRTGDPTENRSEIRDFLISRRAKLAPERVGLPTSRRRRV
                     PGLRREEVAALAGVSTEWYTRLEKGHISGVSEDVLEAVAQALLLSEDERTYLLELARAA
                     RPTRRRSHRRKDVKIPSPVQWMVDSMTMAPAFVRDGRLDIVAGNALCRTLYSPMFDSDT
                     TGDRGCANFPRYFFLDPGSRDFFVDWEEGARATVAVLRAEAGREPHDRALRELVGELST
                     LSPDFRTMWASHDVRIRHEGIKRLNHPEVGRLEMTFRSLDLPLPQRAVHDLIIYTAEPG
                     TPSEDRLKLLASWTASQTSATEPIRPSR"
     gene            complement(4525..4908)
                     /locus_tag="BV401_RS00580"
                     /old_locus_tag="BV401_00560"
     CDS             complement(4525..4908)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665611.1"
                     /locus_tag="BV401_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00560"
                     /product="hypothetical protein"
                     /protein_id="WP_193524933.1"
                     /transl_table=11
                     /translation="MSTAIHVILDSSAMVAAGRGNALASRLIHRAHAESGWLLHATTCA
                     LIEADRERRGTAEHIAALPGLTFLDLDLPAALVVAHGHDDWAVAHTLYAAQPSSDRPEG
                     AVIATTAASLWEPHPVRTLDLNP"
     gene            complement(4905..5162)
                     /locus_tag="BV401_RS00585"
                     /old_locus_tag="BV401_00565"
     CDS             complement(4905..5162)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981677.1"
                     /locus_tag="BV401_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00565"
                     /product="hypothetical protein"
                     /protein_id="WP_069870915.1"
                     /transl_table=11
                     /translation="MSDANIRIPEEARDRLAEVAAAEGLSLRAYLAHLAETVLTPTERA
                     ERAERARAVLKEWNGYDPDPAQQAELDAELDRRLGQADAA"
     misc_feature    complement(5269..5283)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.7"
                     /tool="antismash"
     gene            5538..6235
                     /locus_tag="BV401_RS00590"
                     /old_locus_tag="BV401_00570"
                     /pseudo=""
     CDS             5538..6235
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131513.1"
                     /locus_tag="BV401_RS00590"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00570"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRGDLTDEQCAALEPLLPKGARVGRPPVWPRRRLIDGIDSTVCR
                     AHQHAAGARKQGDLQKEPPGGIFTEPRDHGLGRSRGGFTTKLHLAVEQGQMPMSIVITA
                     GQRGDSPQFEPVLNQVRVAHLGPGRPRTRPDRVRADKAYASRKNRAYLRRRGIRCTIPD
                     KADQIRNRKKLGSRGGRLPRFDAEDYTARHAVECGIDRLKRHRAVATRYDSLRSATRPL
                     SS"
     gene            complement(6386..7414)
                     /locus_tag="BV401_RS00595"
                     /old_locus_tag="BV401_00575"
     CDS             complement(6386..7414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026882.1"
                     /locus_tag="BV401_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00575"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_079255651.1"
                     /transl_table=11
                     /translation="MFRHLAVAVMALAVVTATPAAATPGLVPAANREIVFTADGTTGYG
                     TLHVPEHRAGQRLRAALLLPGSGPTDRDGNQPPGSAPDTLAQLADGLDRDGIATLRFDK
                     YGTGRTGLGAYRDHPEELDYPAFVRQARAAYESLRDQPETNPHALLIVGHSEGAMTGLL
                     LGGTVRPRPAGLALLQPQAIRMLDLVALQLKAQVAEATRQGQFTPEQQRTVNAAIDAAV
                     TSLRKHRPVDTTDLPAAIAQLFEAFQGPNARFVLSDDVVYPPDTAAALRPGTKVLLTCG
                     TNDAQVPCVTTNALTAALHHAHAGGPVRVTLPKVDHLLHDADHPNTLAPPVLDTLRRFA
                     RH"
     gene            complement(7419..7778)
                     /locus_tag="BV401_RS00600"
                     /old_locus_tag="BV401_00580"
     CDS             complement(7419..7778)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007497026.1"
                     /locus_tag="BV401_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00580"
                     /product="hypothetical protein"
                     /protein_id="WP_079255652.1"
                     /transl_table=11
                     /translation="MALIRIDGDDLVVVIEGLDKLWSFKGSLTIPLANVRGATADPGIA
                     AEPKGIRAPGSRVPGVITAGTFHQDGEKVFWDVRDPSKAVVVELADERYARLVLQVDDP
                     RATVALVENAMSEGR"
     misc_feature    7773..7783
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(7793..8293)
                     /locus_tag="BV401_RS00605"
                     /old_locus_tag="BV401_00585"
     CDS             complement(7793..8293)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354065.1"
                     /locus_tag="BV401_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00585"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_079255653.1"
                     /transl_table=11
                     /translation="MGRPRAFDEDEAVRAAVGLFGGRAYDGVSVDDLVTHLGVHRNSLY
                     KTFGSKRGLYLIALRRHLTDDVRPLLDALAGESDAAAALRLVTSADLGLLLLAAIERAP
                     VDEEVASEVAAALTAIDQVIADALGVPADMATALTAAALGILLRGNPDNAVNALTERLI
                     PLT"
     misc_feature    8330..8343
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            complement(8463..8672)
                     /locus_tag="BV401_RS42645"
     CDS             complement(8463..8672)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS42645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_148666216.1"
                     /transl_table=11
                     /translation="MNSLRASNIPLVGSRIAALRALVSEIPPAIAAQAIGYTAQCAERH
                     AQVSGTTWTNYVPNRRRPNQLTTS"
     gene            8772..9101
                     /locus_tag="BV401_RS00610"
                     /old_locus_tag="BV401_00590"
     CDS             8772..9101
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS00610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BV401_00590"
                     /product="hypothetical protein"
                     /protein_id="WP_079255654.1"
                     /transl_table=11
                     /translation="MFSQDLPERLWNGDRAVFAEGDLYLGSVEVEIVHGQGGNAGEALG
                     EEHEQDGGCTVSQKTAALRIEKLVQKLEPIALGEGLVGLLVRMSQPQMRSGPSRARCWI
                     RDVLF"
     misc_feature    complement(8821..8836)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.03"
                     /tool="antismash"
     gene            9134..9910
                     /locus_tag="BV401_RS00615"
                     /old_locus_tag="BV401_00595"
     CDS             9134..9910
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379294.1"
                     /locus_tag="BV401_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00595"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_079255655.1"
                     /transl_table=11
                     /translation="MTEVAQQAVFWTDDSPVCEPMGHGEDIAAHFHDYGQLRYAASGAL
                     VTTTKVGTWVAPANRITWVPPFYVHSSRSYGETDVRVLPVPEALSEELPPEPSVFVASA
                     LLREAYLAMSSEHEPAASERGRLLLAVIGAELIRAPQEPLRLPEPSDPRLKAVTDLLHA
                     DPAISATLAELGRRTGSSERTLSRLFGSELSMSFHQWRTLLRIQRALLGLSEGTSVTET
                     AMRLGWANPGSFINAFTELVGQTPGRYRSTAGAAHS"
     gene            10001..11596
                     /locus_tag="BV401_RS00620"
                     /old_locus_tag="BV401_00600"
     CDS             10001..11596
                     /NRPS_PKS="Domain: AMP-binding (34-428). E-value: 1.7e-82.
                     Score: 269.1. Matches aSDomain:
                     nrpspksdomains_BV401_RS00620_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="BV401_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00600"
                     /product="AMP-binding protein"
                     /protein_id="WP_079255656.1"
                     /sec_met_domain="AMP-binding (E-value: 9.2e-84, bitscore:
                     280.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHHLPGHGTAASAAATTASSGVTLGDLIIQVLSRHSSSEAFVAG
                     DRRLTYAHVRDLLSQYVAALAHRGVGLGVGVTMLSPNMPESWIVQAATYLLGGRFTGLL
                     PLASVTDHITVCEDAEATVLVVTAPLEEHGRQVLAEVDSLRHLMVIPAAGGPPEGEPPA
                     VRSLDRGPATEMDVAWLQYTGGTTGRPKGVMQPHRSMVQMVYAYLADFEQPHLPRYLAA
                     APLTHAAGLAVIPALLRGGTVVIEQGFEPSRFLAVIEAERINCVSGLPTMIYTLLDQER
                     PETRDLSSLEVIWYATGPMSPVRLAEARERIGPVFSQIYGQTESAGIGTVLTKAAHETA
                     SLERLASCGRPVVGNRIRLIDDDGHDVPLGEVGEIAMQSRGVMHGYKNLPDETEAALKG
                     GWLHTGDLARQDAEGLIYIVDRKKDMIISGGFNIYASEVEAVLTAHPSVGSAAVIGVPD
                     SRWGEIVTAFVVPRPGQQVDIPALQSYVKQVKGSMYAPKKVVVVDSLPATPVGKIDKKR
                     LRAPFWADSTRNIH"
     aSDomain        10103..11284
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS00620_AMP-binding.1"
                     /evalue="1.70E-82"
                     /label="BV401_RS00620_AMP-binding.1"
                     /locus_tag="BV401_RS00620"
                     /protein_end="428"
                     /protein_start="34"
                     /score="269.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RHSSSEAFVAGDRRLTYAHVRDLLSQYVAALAHRGVGLGVGVTML
                     SPNMPESWIVQAATYLLGGRFTGLLPLASVTDHITVCEDAEATVLVVTAPLEEHGRQVL
                     AEVDSLRHLMVIPAAGGPPEGEPPAVRSLDRGPATEMDVAWLQYTGGTTGRPKGVMQPH
                     RSMVQMVYAYLADFEQPHLPRYLAAAPLTHAAGLAVIPALLRGGTVVIEQGFEPSRFLA
                     VIEAERINCVSGLPTMIYTLLDQERPETRDLSSLEVIWYATGPMSPVRLAEARERIGPV
                     FSQIYGQTESAGIGTVLTKAAHETASLERLASCGRPVVGNRIRLIDDDGHDVPLGEVGE
                     IAMQSRGVMHGYKNLPDETEAALKGGWLHTGDLARQDAEGLIYIVDRKKDMIIS"
     CDS_motif       10532..10591
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS00620_0001"
                     /evalue="3.10E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="BV401_RS00620"
                     /protein_end="197"
                     /protein_start="177"
                     /score="19.8"
                     /tool="antismash"
                     /translation="AWLQYTGGTTGRPKGVMQPH"
     CDS_motif       11102..11188
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS00620_0002"
                     /evalue="1.10E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="BV401_RS00620"
                     /protein_end="396"
                     /protein_start="367"
                     /score="21.0"
                     /tool="antismash"
                     /translation="PLGEVGEIAMQSRGVMHGYKNLPDETEAA"
     CDS_motif       11453..11503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS00620_0003"
                     /evalue="1.80E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="BV401_RS00620"
                     /protein_end="501"
                     /protein_start="484"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="YVKQVKGSMYAPKKVVV"
     gene            11642..12526
                     /locus_tag="BV401_RS00625"
                     /old_locus_tag="BV401_00605"
     CDS             11642..12526
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.4"
                     /locus_tag="BV401_RS00625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00605"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_148666217.1"
                     /transl_table=11
                     /translation="MNVPPARLIDFHSHWGTERGWKGSPYETAEDREALRGYFKWGMSF
                     VSDEEQAVQFRRANVKAMLDFAFTHTMDAGALRDQHDYAFDYARKHPDVVLGNWIGIDP
                     TQPAHVKELERCLSEGTGLVGLTVHSFTPAGTPDQPEWETCLNMCIEANRPILVHVGMS
                     ATGAGTRGGMGITLEGCHPRYVDRVAAKHPDLNVIAARVAWPWQSEMIAVALHKANVWM
                     ELHGWSPRYFPDELKREIGKRLRKKVFFGADYPMLTHERLVEEWREEGFSSGVLDDVFS
                     GNAETFLTSIGVQ"
     gene            12526..13326
                     /locus_tag="BV401_RS00630"
                     /old_locus_tag="BV401_00610"
     CDS             12526..13326
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="BV401_RS00630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00610"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_079255658.1"
                     /transl_table=11
                     /translation="MDVGLTGKVAIVGGGSEGLGYAIADRLLKEGANVTLFARRAEKVT
                     AAAQQLAGTYGEEKVLGLTADCSADTDIERVTASTLERFGPAVHVLVTNDGGPPIRRIS
                     ELTDEVWLKAFERHFFYVVRSVRATLPHMTAEGGSILNVVSGVVERPAVGMAASVGVWS
                     AVIGYAKTLALEVARQNINVNTLLSGFFDTALLGGMLERQPQLSKAGLGNGVPMGRIGE
                     PREFADLVGALVSPNLRFVTGAVIPVDGGAGIGMGASFDSPTSK"
     gene            13349..14380
                     /locus_tag="BV401_RS00635"
                     /old_locus_tag="BV401_00615"
     CDS             13349..14380
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131971.1"
                     /locus_tag="BV401_RS00635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00615"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_079255659.1"
                     /transl_table=11
                     /translation="MKISTMLPYGTDPREAADHIIRLEAAGLDTVWVAEGYGYDSPTLM
                     GYLAARTSSVEIGAAILNVYSRTPTMLASTAAGLDSVSGGRAIIGLGASNPKIIEGWHG
                     MPFVQSTGRTKETVEIIRAALRREAVDYSGRSFEIPLPPGQGTGLGEPLKIMTKPLRPS
                     VPLYTAALGPKSVEGAAEYADGWLPFLYSPEGAAGVWGDALAAGTAKRSENLMPLEVVA
                     GGIVAIGEDVKEILGLARPILALYIGGMGARGKNFFNDLVRRYGYEAEAEEIQDLYLDG
                     KKKEAEAKVPFQLLEQVNLVGPASYVRERIEAFRESGVTNLQVTPTGDDPAGLVRQLKE
                     WVA"
     misc_feature    complement(14498..14513)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.43"
                     /tool="antismash"
     misc_feature    14701..14721
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.97"
                     /tool="antismash"
     gene            <14837..>14980
                     /locus_tag="BV401_RS41650"
                     /old_locus_tag="BV401_00620"
                     /pseudo=""
     CDS             14837..>14980
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008745676.1"
                     /locus_tag="BV401_RS41650"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="BV401_00620"
                     /product="IS1380 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTVHDPGKILLDVALAVALGGDCLADVGMSRAEPAVFGPVASDPT
                     VSR"
     gene            complement(15109..15510)
                     /locus_tag="BV401_RS00640"
                     /old_locus_tag="BV401_00625"
     CDS             complement(15109..15510)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="BV401_RS00640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00625"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_217490030.1"
                     /transl_table=11
                     /translation="MPSASAVIASPHSSTRPWFRGRRRCEPGRQIRENYAEPLSIEELA
                     KAAQMSRSSFHEHFKSVTAMSPLQYQKQLRLHAARRLILDGHADATTASRHVGYDSASQ
                     FSREYKRLFGAPPMRDIARIRATPSAVVA"
     gene            15488..16225
                     /locus_tag="BV401_RS00645"
                     /old_locus_tag="BV401_00630"
     CDS             15488..16225
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059370.1"
                     /locus_tag="BV401_RS00645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00630"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_079255660.1"
                     /transl_table=11
                     /translation="MTAEADGKVIALFGAGPGLGAAVAHRFGREGYRVALVARRGETLR
                     VLAEELAGEGVEAVPFPADLSRSEAIPDLVADITARLGPIGAVYYAPITGESPFLPATE
                     VTPQILAGYVDLYLYSPIAVVNAVLAGMLGRGDGAILVGHGGSAAHPAPFRSGIGPIMS
                     ATRNYLYSLHGELAGKGVYVGTVTISAVILGSTGAAAVDTELITQLGLPTAEPSDLADL
                     LWNMADARDRVEVAWPAPPESQS"
     gene            complement(16552..16815)
                     /locus_tag="BV401_RS43030"
     CDS             complement(16552..16815)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS43030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_141765357.1"
                     /transl_table=11
                     /translation="MVEIGEFDRPGAREERHFVTHLGSAEILVGGGDHHETGAGGQCRS
                     LASVVANLEQRAGISPVGAGAVYVTDVVSPSIRDTGPASHIS"
     gene            17184..18785
                     /locus_tag="BV401_RS00655"
                     /old_locus_tag="BV401_00640"
     CDS             17184..18785
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084802.1"
                     /locus_tag="BV401_RS00655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00640"
                     /product="GMC family oxidoreductase N-terminal
                     domain-containing protein"
                     /protein_id="WP_079255661.1"
                     /transl_table=11
                     /translation="MPSSESFDYVIVGAGSAGCVLAARLTEDPAARVLLLEAGAEDTDQ
                     NIKAPAALGLLFHSGVDWDYQTVEQEAAGRAFYWPRGKTLGGSSSTNVMLYARGQRDDY
                     NSWRDEYGATGWGFDDVQPYFVRAERNKRHGPPSHGTEGPLHVEDRPYTHELSRAWVDA
                     ALAWGLPPVEDIAGASPQGAGLTQVTCRDGRRWSTADAYLRPALDRENLTVRTGALATR
                     VIMEGSKATGVAYLRDGTEHVARAGGEVVLSGGVVNSPQLLMLSGIGPSDVLREHGIDA
                     AVVLPGVGRNLHDHVLTPVVWETRDSSDIIVDLLTPENLQQWAETGGGPFASNYAEAMA
                     YLSVTPGVSRPDMQLTGGPTAFILSGQEMPGRPVFTMNATQLRPRSRGHLTLASTDPRD
                     HPLIDPRYFTDPEDEATLIRGVRAVIEIGDQEPLAAFLDRPYLPAGTDLRALDDATLSD
                     HIRTWSGTAYHPVGTCAMGTGEAAVVDPELRVHGTAGLRVVDASVMPTVASGNINAPTV
                     MIAEKTADLIRGVPAA"
     gene            complement(<18858..>19060)
                     /locus_tag="BV401_RS41190"
                     /old_locus_tag="BV401_00645"
                     /pseudo=""
     CDS             complement(<18858..19060)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008412605.1"
                     /locus_tag="BV401_RS41190"
                     /note="catalyzes the formation of pyruvate and acetaldehyde
                     from 4-hydroxy-2-ketovaleric acid; involved in the
                     degradation of phenylpropionate; frameshifted; incomplete;
                     partial in the middle of a contig; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00645"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /pseudo=""
                     /sec_met_domain="HMGL-like (E-value: 2.9e-16, bitscore:
                     58.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRERFRAYRDVLDPATEFGIHAHQNLSLAVANSVVAVEEGVTRV
                     DASLPGHGAGAGNRPSNRSSPW"
     gene            complement(19146..19904)
                     /locus_tag="BV401_RS00665"
                     /old_locus_tag="BV401_00650"
     CDS             complement(19146..19904)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656166.1"
                     /locus_tag="BV401_RS00665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00650"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_079255663.1"
                     /transl_table=11
                     /translation="MRSTERDDGHNSVLGRAVALLSAFHQDDEYVSLSELARRAGLPKP
                     TAHRLSGQLIDLGMLETGSHGLRLGLRVFELGQLVPRQRGLRDAARPHLENLYRTFGET
                     VHLAVLQGADVVYLDKLTSRITPVAPSRIGGRMPAHATALGKALLAHADPQVRDAVLAS
                     PLERRTPRTIVMRGLLARELGRVRTEGIAREYEESAPGLVCVAHPVRDDSGRVIAAVSV
                     SGRINRLRVDRVAPALRTAALTLARRYRSH"
     gene            20093..20524
                     /locus_tag="BV401_RS00670"
                     /old_locus_tag="BV401_00655"
     CDS             20093..20524
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025939.4"
                     /locus_tag="BV401_RS00670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00655"
                     /product="RidA family protein"
                     /protein_id="WP_069870945.1"
                     /transl_table=11
                     /translation="MSDLTLLEHPTAGSYAPLIITGNLAFVSGHIGWRDDKASVVGVVG
                     RDLSVEQGKVAARDAALAALGTLDREVGLDRVASVVRLFGMVRADPEFAQHPAVIDGAS
                     HVLLDLLGDRGRHSRSAVGMTSLPFGAAVELELVVCLDQ"
     gene            20550..21695
                     /locus_tag="BV401_RS00675"
                     /old_locus_tag="BV401_00660"
     CDS             20550..21695
                     /NRPS_PKS="Domain: Aminotran_5 (76-220). E-value: 6.1e-09.
                     Score: 27.2. Matches aSDomain:
                     nrpspksdomains_BV401_RS00675_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013237.4"
                     /locus_tag="BV401_RS00675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00660"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_079260217.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.2e-06, bitscore:
                     24.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 4.5e-06, bitscore:
                     24.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHAPQPVPPQNRPVTPALFQTAAWQFSDLGQMDGIFSGQIAGAQ
                     YGTVGMPNNLALEAALGRLEGAEASVVANGGMAAIAGTLLTLLGPGKRVIVGREGFSWT
                     LGLLRDLEQWGLEHTAIDLTDLDAVEAALRDETHLVFAETVSNPRLRVPDLSALSTLTH
                     AAGALLAVDNTFATPFHCTPLALGADLVIESATKFLGGHSDAVLGAVSGKTNLIEPIRR
                     RMVRLGSIAAPMDSWLIQRGLMTFVVRMERASRTAAAIAEWLAAHPAVGRVFYPGLTSH
                     PDQEVAAKVLDRGFGAMVTFELAPDFERVNEFTRRLHDITLVHSLGGTQTSLSHPASSS
                     HRLLSAEELSQVGLHPGVLRMSVGLEEPDDLIAELATALGG"
     aSDomain        20778..21209
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS00675_Aminotran_5.1"
                     /evalue="6.10E-09"
                     /label="BV401_RS00675_Aminotran_5.1"
                     /locus_tag="BV401_RS00675"
                     /protein_end="220"
                     /protein_start="76"
                     /score="27.2"
                     /tool="antismash"
                     /translation="MAAIAGTLLTLLGPGKRVIVGREGFSWTLGLLRDLEQWGLEHTAI
                     DLTDLDAVEAALRDETHLVFAETVSNPRLRVPDLSALSTLTHAAGALLAVDNTFATPFH
                     CTPLALGADLVIESATKFLGGHSDAVLGAVSGKTNLIEPI"
     gene            complement(21762..23003)
                     /locus_tag="BV401_RS00680"
                     /old_locus_tag="BV401_00665"
     CDS             complement(21762..23003)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /locus_tag="BV401_RS00680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00665"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_148666218.1"
                     /transl_table=11
                     /translation="MTSTQRSERETLRSEPEALRSGGDTLRPEAEALRSEGGTPPRPEG
                     EAKTSSRPPAGTAARGHKTRRLADELRRGIAELRWPSGKLPTEQELAQDQQVSLNTVRR
                     AVDLLVQEGLVYRKQGSGTYVSSPQASETGYAVGVVVSSLTYYYPRVIAGIERELAQHG
                     SRMLLRCTDWDPAMERGAVNELIRAGSTGLILVPALSHDRADLWPSDPDELSVPTVLVE
                     RGLTLPTTLHEFVCTHHAAGTLSALRYLLSLGHTRIGYMERSSPHTAPQIRSGLSTALD
                     RAGLGPDPVITASLPRWTARDADRFLDRVVDHGITGVLCFADREASLLVSAARRRHLGV
                     PDDLSVISYDDEVADLCEVPLTAVSPPKAEIGRRAARVLAARIADPDAPRRQEALVPRL
                     VIRDSTGPAPAGAR"
     misc_feature    complement(23052..23065)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            23160..24569
                     /locus_tag="BV401_RS00685"
                     /old_locus_tag="BV401_00670"
     CDS             23160..24569
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041518.1"
                     /locus_tag="BV401_RS00685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00670"
                     /product="choice-of-anchor Q domain-containing protein"
                     /protein_id="WP_079255665.1"
                     /transl_table=11
                     /translation="MSVSASLGRRSRLTAVFVCVLLLLGFLADRTAFGAGTPPGAAAAA
                     SYYVDPVNGSPANPGTSAQPWKSFQDIFAQGRTYGSGDVVYLRSGNYGAAVVNGGVSSG
                     NRTIKAAPGAVPRMKTLRFAAGATHWTVDGVLVSPQEADGTYTTGNLVQFDSGATNDIL
                     QNSQVRAASDAAADTWYNNDWVNRSGTGIVVIGSNNQVLNNQIRNVRNGVMLERTSTAG
                     AGATGGVVRGNSVNHFWEDAYRCKVSGCLVEYNSAVNSYAVVPPGTEADPPHRDMFQSY
                     RGDGSFTPVTNVVLRGNVFISRMGTRYSKIPFQYNGKYTIQGLGAFDGPYSNWTIENNV
                     VQVEVGLAMGLYGMNNSRIVNNTVVPRYPAADSEIRLTNQKDGTPPTGDIVRNNLAHTF
                     NTAAAADAQHSNNITVGTSYSTYFVNYQSGDLHLKAGNPAIGAATNRDAPTIDADRKAR
                     SAPYDVGAYEF"
     gene            complement(24748..24882)
                     /locus_tag="BV401_RS45470"
     CDS             complement(24748..24882)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS45470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_257788904.1"
                     /transl_table=11
                     /translation="MVHELTHQFFVSGRDLTSYIKSWIYGRTTPPTPGHQDWKPGKPS"
     gene            complement(24921..25940)
                     /locus_tag="BV401_RS00690"
                     /old_locus_tag="BV401_00675"
     CDS             complement(24921..25940)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="BV401_RS00690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00675"
                     /product="DMT family transporter"
                     /protein_id="WP_079255666.1"
                     /transl_table=11
                     /translation="MHSRAQRSLHTVCACPIRAPLRPRGVLMSRRGLLLFMITSVLWGV
                     PYLLISVALEGMGPASVVAGRVALGALVLLPVAWRRGLPRLLRERWRPLLLLAVMEVAL
                     PFTLIAVGERTVPSGLAGVLIATEPLFILALGLFWGKRERLARGAWAGVALGFLGVVVL
                     LGVAVAGAGALLVLAAAACYAVGAVLLHRLFPDVPPLTVSAGMLTLAAGPLLAAAAIAE
                     PAPQVTTRVLLAVLGLGVACTAGGFTAFFALIATEGPARAAFITYVAPVVAVASGVLLL
                     SEPVTTRTITGTVLILAGAALAARRRSSDTPSADSAAARPSRTGTIPAAENEQAGGAR"
     gene            26002..26460
                     /locus_tag="BV401_RS00695"
                     /old_locus_tag="BV401_00680"
     CDS             26002..26460
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013224.4"
                     /locus_tag="BV401_RS00695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00680"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_079255667.1"
                     /transl_table=11
                     /translation="MATLDSTDWQLLGLLQEDARLGFRELARRVGLSPPAVAARVRRLE
                     SLQVITGYGARVDPAKAGWPVQAFVVLSTTGVRQSHQTAHIAQAAPHILEDHRVTGTDD
                     HILRVVAHEIGALEPLIDQLNELGKPATSFVLSSPKAWAPVPPPTTSD"
     gene            complement(26624..27130)
                     /locus_tag="BV401_RS43280"
     CDS             complement(26624..27130)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BV401_RS43280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162496075.1"
                     /transl_table=11
                     /translation="MAIPPTASELTFTGEPLGTTCRYGEESVVFNDRRLRRVKADATGL
                     HTFDEIPQRLLKIPQQREQRLSITPQQRQAAAALYGCPVWRIGPCAGYSTPIHRYACPR
                     RASRRPSCTDATGHLRIVEDELIARTLARRQSEPCLSSGNSVITSSKTTARCSSVRDVP
                     RTYRV"
     gene            complement(<27212..>27324)
                     /locus_tag="BV401_RS44315"
                     /pseudo=""
     CDS             complement(<27212..27324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018106289.1"
                     /locus_tag="BV401_RS44315"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="DUF6009 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MASGTFRRAPSGSCPTAVTTTPTVRTPRVHPPKPSTP"
     gene            27801..28547
                     /locus_tag="BV401_RS00705"
                     /old_locus_tag="BV401_00685"
     CDS             27801..28547
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (2-86). E-value: 1.5e-06. Score:
                     20.1. Matches aSDomain:
                     nrpspksdomains_BV401_RS00705_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="BV401_RS00705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BV401_00685"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_079255668.1"
                     /transl_table=11
                     /translation="MTTALITGGSSGIGEGFARRLASEGHDLVLVARNKERLDAAAAHL
                     RDRYGVHVDTIEADLTTMDGCSQVEDRLRNSAVDILVNNAGFGLPAPYPRSAIADEERM
                     IDILIRTPLRLTYAAIPGMTERGRGAIFNIASVAGLLPTGTYGAAKAWLIRFSESLRHD
                     LKGHGVRVLAVAPGFTRTPGAAGIPVPHWLWLEVDQVVDQAMKDLKRGRPVSIAGWHFK
                     MYDQAVRHLPRRIVATMARSRKRLRG"
     aSDomain        27807..28058
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BV401_RS00705_PKS_KR.1"
                     /evalue="1.50E-06"
                     /label="BV401_RS00705_PKS_KR.1"
                     /locus_tag="BV401_RS00705"
                     /protein_end="86"
                     /protein_start="2"
                     /score="20.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALITGGSSGIGEGFARRLASEGHDLVLVARNKERLDAAAAHLRD
                     RYGVHVDTIEADLTTMDGCSQVEDRLRNSAVDILVNNAG"
     CDS_motif       27813..27902
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BV401_RS00705_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BV401_RS00705"
                     /protein_end="34"
                     /protein_start="4"
                     /score="17.9"
                     /tool="antismash"
                     /translation="LITGGSSGIGEGFARRLASEGHDLVLVARN"
ORIGIN
        1 taccattgcg tcagcgtccc catgctcggc gcaatccacg gaatcgagca cgttgccaag
       61 agagtgattg catatgccgt cgcgactgcc atgacctcca ttctcctcat tcctgttgca
      121 ggaatgagtt ggacctatgc aatggtggct gtagtcggtg gagcgtggtt cgtaggggaa
      181 gctcttcgac tccaaaccac tgcccgtcga gcggaagccg ccgcgcgacc aatgcggatg
      241 tttgtgatat cgaatgcgta tcttgcattg ttgttcggcg cagtggccat cgatacactc
      301 gtgaaatact gactcagctg aaaactctgt cgcaccgacc tcccgcgcct gctcctaaca
      361 ttcagcgcgc attgtttact gccacgatct caagcgcatc gttcacccac acggaaactg
      421 gaatagctga ctaatgaacg tgcaaaaaca cacccgccgg aggttcctga ccagcagtgc
      481 tgctgtcacg ctgggcgcgg cagcagtagg aactgccgcc ggaacgcagc tcccacacaa
      541 aggaacggcc agcgcggcgc cctcgccgac acaccatacg ccctcctcta tcccgttctt
      601 tggcgtccac cagccgggca tcgccgatcc gaccccaacc aacgcggttt ttctcgcctt
      661 cgatctcaaa gactcgacag taaaatctga cctggcggac gtcatgcgag cgtggacggg
      721 tcttgcggcg gctctgatga ggggagacac ctctgccgat acatcactgg tgtccaccgg
      781 ctcaacgcca ggaaagttca ccatgaccgt ggggctcgga ggcgccgctc tcgaccaact
      841 tgacataaag cgcacgcctg cactcgtcga cctgccgttg ttccccgggg atgaactcga
      901 agtcgcagcc tcacatggcg cggtcttcgt gcagctttgc tccgatgacg ccatatacct
      961 tgggggcgcc gtacgtgccg ttcgcgcggc tgcgaagcgg gtcctgcggc cccgctggca
     1021 gatgaatggc ttccgcggtg ctgccgcctc gaccgctagc agcaatggcc gcaatctcat
     1081 gggccagatc gacggcacca ataacatcgc cgtcagccgt gcatccacag gtgggccggt
     1141 ctgggtcgac gcagtttagc taaggatccg tccggggcac tgatcatccc ggacgacgcc
     1201 catatccgcc ttgccgcgcc ccgccgaggc cctggcgaag agatgctccg tcggtcctat
     1261 tcctactcga tcggacaggc aagtggcgcc gcaggcgatg aagacgctgg cctgattttt
     1321 gtctcctacc aggccgatcc gactaccagt tttataccgg tacagcagcg actggccaaa
     1381 tcagatgccc tcgcacactt cacgctggct acgtccagcg ccctgttcgc gatcctgccc
     1441 ggggtcgttg ggagacatga ttggtatggg cgatcgctcc tgagctaatc gcgaaaatgg
     1501 tttgccgatt aggcgttgac atatccgact tcgtcagttg atggacgccg cgagtctccg
     1561 ctgcgcatat tcgccactcg cctcaatgag gtttacagaa aggttgcagg tgtgtcgacg
     1621 tctacacgtc gcttgttctc ggttgtaata gctataggca tcgccgccac actcgccggc
     1681 tgcacagccg gcggctcagc aaaggttggt gctcgaacat cggccatagc agtactggac
     1741 tccaaagatc ttggcgacat actcgtcgat ggcaagggca acgttctcta tgcctttaag
     1801 ccggacaacg cctcgacggt tagctgcaca ttcggctgtg cgacggtctg gcccccactc
     1861 tcggtcgccg ataatgcgtc caccgcagct ggtgacggag ctgacgtagc cctattgagc
     1921 aagctacccg accacgctgg cggtcacgtc gtcacttata acggttggcc gctctaccga
     1981 tacgccgccg ataaggcacc tggtcaacat cgcggacagg acgtcttcct gaatggcggc
     2041 tactggtacg tcatgaaacc tgacggtaaa cctcttatgc catgaagcgc gaagtcggtg
     2101 agaggcgaac aagcagccga actgtcagag ggcggttact gtaatcgtcg ggcgcgcaaa
     2161 gcagccggcg gccgcttcgg taaggatgcc gagtttgacc aggcgcttca gcttggcccg
     2221 ggtgccttcg atgttcttcg gcaacggttc ggggctccgc ctggcagacg tccttggccc
     2281 gcaggggtct ggtcgactcg ttgaaggcgg caaggatgcg cgggtagttc gggcggggat
     2341 gcggggagtc ggcgggcgag gccggtgaca gtcttgcggg tgcccaactg acctacccgt
     2401 caggcaggtt ggaaaaggct cagtgagcgg cgtggtgtgg aaaccgagcg tggtcagacg
     2461 ggctggccca tgggccggat ggtcagggtg ttgaggtcga cgcctgccgg ttggtccagg
     2521 gcgaagcaga tggcctcggc gatgggctgg ggaggcaggg cgaagggggg aacgctggcg
     2581 ccttgccaga agggtgtgtc gatcatgccg gggttgacaa gagtgacacc gatgccgcgg
     2641 gtcgtggcgt gcagtcgcag gttctcggcg agtccggtgg tagcccactt ggtggccgag
     2701 tagagattgg caggagagtt cttcagcccg gcgacgctgc cgatgagcac cagccgtccg
     2761 ccagtggcct cgagatgggg cagggtggca tgagccagca gggcggggcc gaggacgttg
     2821 gtgagaacca tcggcgccca cgacgtcggt ttaccggccc cgatggagtc accggacatg
     2881 aatccggcgt tggccaccgc cgcgtcaagg gcaccgaaat gctccacggt gcgggtcacg
     2941 accgactcgg tggcctgcca gtccgccgcg tcagcgacca gacccagcag ccggtcgggg
     3001 tggccggcct cgtcgaggaa agtcttcagt ttgctctcgt tgcggccggt gaccgccaca
     3061 cggtggccgc ggtcgaggag caaccgcgcg gtgtgggcgc cgataccgct ggtcgcgccg
     3121 gtgatcagta cggtcttgcc agtcatggtc atgctcctga ggtgtggatg ggctacggcg
     3181 gacggcggcc cgcgatgaag aagtgccgtt cgaatccgcc gaccccagac aaccggcgcc
     3241 gtcagagacg ggcaaggtcg cgtttatggg gggtataaac acaacctctc tatcggcagg
     3301 gccatgggta agctggacga atggaacctc cgtccgaaaa ccgcaccggt gatcccaccg
     3361 aaaaccgctc ggagatccgc gacttcctca tcagtcgacg cgccaagctc gccccggagc
     3421 gggtcggact gcccaccagc cgacgccgcc gggttccggg actacgacgc gaggaggtcg
     3481 cggccctcgc cggcgtgagc accgagtggt acacacggct ggagaagggc cacatcagcg
     3541 gcgtctccga ggacgtgctg gaagcagtcg cgcaggcatt gctcctcagt gaggacgagc
     3601 gcacctacct tctcgaactg gccagagcgg ctcgccccac ccgccgcagg tcgcaccgcc
     3661 gcaaggacgt caagatcccg tctcccgtcc aatggatggt ggactccatg accatggccc
     3721 ccgccttcgt acgcgacggc cgtttggaca tcgtcgccgg caacgcgctg tgcaggaccc
     3781 tgtactcacc gatgttcgac agcgacacca ccggcgaccg cggctgcgcc aatttccccc
     3841 gttacttctt cctcgacccc ggctcccgcg acttcttcgt cgactgggag gaaggcgcga
     3901 gggccacggt cgcagtgctc cgcgccgaag ccggacgtga accccacgac cgggccctgc
     3961 gtgagcttgt cggcgaactg tccacgctca gccccgactt ccgcaccatg tgggccagtc
     4021 acgacgtccg aatccgtcac gaaggcatca agcggctgaa ccatcccgaa gtcggccgtc
     4081 tggagatgac cttccgctcc ctggacctgc ccctgcctca acgggccgta cacgacctga
     4141 tcatctacac ggccgagccg ggcaccccct cggaggaccg cctcaaactc ctcgccagtt
     4201 ggacagcatc gcagacctca gccacggaac cgatccgccc gtcccgctga cctcacgcgt
     4261 tcatgaggtg gcgtccaggg gttgagcctt ttccaacctg cctgagccgt gcctcgcgga
     4321 atgctcgccc gagcccatcg ccatcgcggc ccgccgaccg ctcgctccac cccgccccgc
     4381 tccgccccaa cgcagtggcc gaggatgcag gggtggttga aaggcaacgg tcagagggca
     4441 gcctccgtca ggaccatgcc ccgccggatc ccccgttacg gagtggaacg gtacggcgcc
     4501 gcacgatttg ctcgagcgtg cgggctacgg gttgaggtcg agggtgcgga ccggatgagg
     4561 ttcccacaag gacgctgctg tggtggcaat gacagctccc tccgggcggt ctgagctggg
     4621 ctgggccgcg tacagcgtgt gtgccacggc ccagtcgtcg tgcccgtgtg ccaccacgag
     4681 ggcggcgggt agatcgaggt ccaagaaagt aagaccaggc agagcggcaa tatgctcagc
     4741 tgttcccctc ctttcccggt ccgcttcgat caaggcgcag gtcgtggcgt ggagaagcca
     4801 gcccgactcg gcatgggcgc ggtgaatcag ccgggacgcc agggcgttgc cgcggccggc
     4861 agccaccatg gcggagctgt cgaggatcac gtgaatggca gtgctcacgc agcgtccgcc
     4921 tgtcccaggc gtcggtccaa ctctgcgtcg agttccgcct gctgagcagg atcggggtcg
     4981 taaccgttcc attccttgag cactgcccgc gcccgctcgg cccgctcggc ccgctcagtg
     5041 ggggtcagga cggtttcggc gagatgtgcg aggtaggcac gcagggacag gccctcggca
     5101 gcagcgacct cagcaaggcg gtcacgtgcc tcctcaggga tccggatatt ggcatcagac
     5161 atacagacac tccttccagc caccaccagg gtacgggtac gcacccgtac ccgcaatgtc
     5221 tcgcctacga gggacggagc tcccgcgtct gatggccatc ccccgaagcg gaacagatcg
     5281 accacaggtc ccacacctgc gcgcgccatt tccacccagt ggtcagcctc cgcgaacgtc
     5341 ccgggacagc ctgatgggtg gcaacccccc ggacaccaac gagtgacggt cacgcgctgc
     5401 atctcgacct gtatccgtca ggtttgagtc gagtgcgaca gttacagggc ttcggacggt
     5461 ggttcctctc gtacaccttc tcctcgctgc caggccgtgt atcgaaagtg aatcttgggc
     5521 tgtgaatgat cacgttcatg ggtcggggag atctcacgga cgagcagtgc gcggcgctag
     5581 agccgttgtt gccgaagggt gccagggtgg ggcggccccc cgtctggccc cggcgtcggc
     5641 tgatcgacgg catcgactcc acggtctgcc gcgcccacca acatgcggcc ggagcccgca
     5701 agcaaggcga cctacagaag gaaccaccgg gcggcatctt caccgagccc cgcgatcacg
     5761 ggctaggaag gtcacgcggc gggttcacca ccaagctgca cctggctgtc gagcagggtc
     5821 agatgcctat gtccatcgtg attacagccg gacagcgcgg cgactcccct cagttcgagc
     5881 ccgttttgaa ccaggtccgt gtcgcccacc tgggaccggg gcgtccgcgg acccggcccg
     5941 accgggtccg cgccgacaag gcgtatgcgt cccgaaagaa ccgcgcctac ctgcgccgac
     6001 gcggcatccg ctgcaccatc ccggacaagg ccgaccagat ccgcaaccgc aagaagctcg
     6061 gctcacgtgg tggccgactg cccaggttcg acgccgagga ctacacggct cggcatgccg
     6121 tcgagtgcgg cattgaccgc ctcaaaaggc accgtgctgt ggccacgaga tacgacagct
     6181 tgcggtccgc tacgaggcca ctgtcctcgt agcagccatc aacgagtggt tgtgaccagc
     6241 accgtcagga aaggtgggcg gagggccaat ggagtctggg tggttcaggg gttgatggcg
     6301 tgctcggtga actggccaca agagcggaac cccaggcggc ggtaggcggg atggcaccgc
     6361 cactcgggga cgtcctcggg cggcgtcagt gtcgagcgaa ccggcgcagg gtgtcgagta
     6421 cgggcggcgc gagcgtgttc gggtggtcgg cgtcgtgcag cagatggtcc actttcggca
     6481 gcgtcactcg gaccggtcca ccggcatgcg cgtgatgcag ggcggccgtc agggcgttcg
     6541 ttgtgacaca ggggacctgg gcgtcgttcg tgccgcacgt cagcagcacc ttggttcccg
     6601 gccggagtgc ggcggcggtg tccggtgggt agacgacgtc atcgcttagc acgaagcggg
     6661 cgttggggcc ttggaacgcc tcgaagagct gggcgatcgc ggcgggcagg tcggtggtgt
     6721 cgaccggtcg gtgtttgcgc agggaggtga cggcagcgtc gatggccgcg ttgacggtgc
     6781 gttgctgctc cggtgtgaac tggccctgcc tggttgcttc ggcgacctgg gccttgagtt
     6841 ggagcgcgac caggtccagc atgcggatcg cctgcggttg cagaagcgcc aggccggccg
     6901 ggcgcgggcg gacggtgccg cccagcagca gccccgtcat cgcgccctcg ctgtgcccga
     6961 cgatcagcag cgcatgcggg ttggtctccg gctgatcgcg caacgactcg taggcggccc
     7021 gtgcctggcg gacgaatgcc gggtagtcga gttcttccgg gtggtcccgg taggcgccga
     7081 gtccggtgcg gccggtgccg tacttgtcga accgcagcgt ggcgattccg tccctgtcga
     7141 gcccgtccgc caactgtgcc agggtgtccg gtgcggaccc gggcggttga ttgccgtcgc
     7201 ggtcggtggg tccgctgccg ggcagcagca gtgccgcccg cagccgttgc ccggcacgat
     7261 gctcgggaac atgcagggtg ccgtacccgg tcgtaccgtc ggccgtgaag acgatctcgc
     7321 ggttggcggc aggcacgaga ccgggcgtcg ccgcggccgg ggtggcggtg acgacggcca
     7381 gtgccatcac agcgactgcc aagtgtcgaa acattggcct acctcccttc agacatggcg
     7441 ttctcgacca gagcaacagt cgcgcgaggg tcgtcgacct ggagaaccag gcgtgcgtac
     7501 ctctcgtcgg cgagttcgac cacgacagcc ttcgacggat ccctgacgtc ccagaagacc
     7561 ttttcaccat cctgatggaa tgtgcccgcg gtgatcacac cgggtacgcg ggagcccggc
     7621 gcgcggattc ccttgggttc ggcggcgata ccggggtcgg cggtcgcgcc acggacgttg
     7681 gctagcggga tggtcagact gcctttgaag gaccagagct tgtcgagacc ctcgatcacg
     7741 acgacgaggt cgtcgccgtc gatacgtatc agtgccatgt caggttccct tttcaggtga
     7801 gagggatgag gcgttcggtc agcgcgttga cagcgttgtc ggggttgcca cgcaggagga
     7861 tgcccagcgc agcggcggtg agggcggtgg ccatgtcggc gggaacgccg agcgcgtcgg
     7921 cgatcacctg gtcgatggct gtcagtgcgg ctgccacctc ggaggcgacc tcctcgtcga
     7981 ccggtgcgcg ttcgatcgct gcgagtagaa gcaggccaag gtcggccgag gtgacgagtc
     8041 gcagcgcggc cgcggcgtcc gattccccgg ccagggcgtc gagcaaaggg cggacgtcat
     8101 cggtgagatg gcggcgcaga gcgatcaggt agaggccgcg cttgctgccg aacgtcttgt
     8161 acaggctgtt gcggtgcacg ccgaggtggg tgacaaggtc gtcaacggac acaccgtcat
     8221 acgcacgtcc gccgaacaag cccacggcgg cacgcactgc ttcgtcctcg tcgaatgctc
     8281 ttggcctacc catgaccact acagtaggca gttgaggaac gatcagtcaa gaacgatcgt
     8341 tcctcaatcc ccgatcccct tcgaggcccg gtcgtccaga agttgcggga gagtctcgag
     8401 actgctgcgc cgtgtcaagc cgcttcaggg agctactcag aacctactga cggcaacgcg
     8461 tatcacgatg tcgtgagttg gttgggccgt cggcgattgg gaacgtagtt cgtccaggtc
     8521 gtgccggaga cctgagcgtg tcgctcagcg cactgagcgg tgtagccgat ggcctgggcg
     8581 gcgatggcgg gcggtatctc ggagaccaga gccctgagtg cggcgatgcg gctgccgacg
     8641 agcgggatgt tgctggctcg cagggagttc atcaggtagg tcgagtggat gtgctgtccc
     8701 gggcagcggc ccgggaagag ccatggactg ctgcgattgg tggcgatgtt gtagggccct
     8761 atgttctcgg cgtgttttct caggacctgc ccgaaaggct ctggaacggg gaccgggccg
     8821 tgttcgccga aggcgacctg tacctcggtt ccgttgaggt cgagatcgtc catggtcagg
     8881 gcggcaatgc gggtgaggcg ctgggcgaag agcacgagca ggatggcggc tgcacggtct
     8941 cgcagaaaac ggcagcgctt cggatcgaga agctcgtgca gaagctggag ccgatcgctt
     9001 tgggcgaggg cctcgtgggg ctgcttgttc ggatgagcca gccgcagatg cggagtgggc
     9061 cctcgcgggc gcgttgctgg attcgtgatg tcctattctg atcgcccgcc aatgcgggct
     9121 acgctgtctt ctgatgactg aggttgcgca gcaggccgtg ttctggaccg acgactcgcc
     9181 ggtctgcgag cccatggggc acggtgagga catcgccgcg cactttcatg actacggcca
     9241 gttgaggtac gccgcctccg gggcgctcgt cacgacgacc aaggtcggca cctgggtggc
     9301 gccggcgaac cgcatcacgt gggtgccgcc cttctacgtc cacagcagtc gctcctacgg
     9361 cgagaccgat gtccgcgtgc tcccggttcc ggaagcactg tccgaggaac tgccgcccga
     9421 gccgtcggtc ttcgtggcca gcgcgctgct gcgcgaggca tacctggcga tgagcagcga
     9481 gcacgagcct gccgccagtg agcgtggccg tctgctgctc gcggtgatcg gcgcggagct
     9541 gatccgcgcc ccgcaggagc cactacggct gccggagccg agcgatcctc gcctcaaggc
     9601 cgtcaccgac ctgctgcacg ccgacccggc catttccgcg acgctggcgg agctggggcg
     9661 ccgaaccggc tcgagcgaac ggactctcag ccggctgttc ggcagcgaac tgtcgatgag
     9721 cttccaccag tggcgcacgc tgctgcggat tcagcgagcg ctgctcggac tcagtgaagg
     9781 tacttcggtc accgagacgg cgatgcgact gggctgggcg aaccccggca gcttcatcaa
     9841 cgccttcacc gagctcgtcg gtcagacgcc cggtcgttac cgctccacag cgggtgcagc
     9901 tcacagctga gcactgcctc cgcctgcctg gcgggttatc cgaaattccg ggcggaacat
     9961 cggtggcacg cccgcccgct cggcggccac gatttgaggc atgtctcacc accttccggg
    10021 tcacggcact gcggcttcgg cagccgccac gacggcatcc tccggagtca cgctaggtga
    10081 cctgatcatc caggtgctca gtcggcacag ctcgtccgag gccttcgtgg ccggtgatcg
    10141 gcgactgacc tatgcgcacg tcagggacct tctctcgcag tacgtggccg cgctggccca
    10201 tcggggagtg gggctcggcg tgggggtcac aatgctcagt ccgaacatgc ctgaatcgtg
    10261 gatcgtccag gccgcgacgt atctcttggg cggccgcttc acagggctgc tgcccctggc
    10321 ctcggtcacg gaccacatca ccgtctgcga ggacgcagag gccacggtgc tggtggtgac
    10381 cgcgcccctg gaggagcatg gacgccaggt cctcgccgag gtcgactccc tgcgacacct
    10441 gatggtgatc cccgccgccg gtggtccgcc cgagggcgag cccccagcgg ttcgatcgct
    10501 cgaccgtggt ccggcgacgg agatggatgt cgcctggttg cagtacaccg gggggacgac
    10561 cggcagaccc aagggcgtga tgcagcctca tcggtcgatg gtgcagatgg tctatgcgta
    10621 cctggccgac ttcgagcagc cgcacctccc gcggtacctg gcagcggccc cgctcaccca
    10681 cgcggccggg ctggccgtca tcccggcact gctgcgtggc ggcacggtcg tgatcgagca
    10741 gggcttcgaa cccagccggt tcctcgccgt catcgaggcc gagcgcatca actgtgtgag
    10801 cggccttccg acgatgatct acaccttgtt ggatcaggag cgtccggaga ccagagacct
    10861 ctccagcctt gaggtcatct ggtacgccac cggaccgatg tcgccggtgc gcctggcgga
    10921 ggctcgcgag cggatcggtc cggtcttctc ccagatctac ggtcagacgg agtcggccgg
    10981 catcgggacg gtcctgacca aggccgcaca cgagaccgcg agccttgaac gactcgcctc
    11041 ctgcggccgt cccgtggtcg gcaaccgcat caggctcatc gacgacgacg gccacgacgt
    11101 tcctttgggc gaggtgggcg agatcgccat gcagagccgc ggggtgatgc acggctacaa
    11161 gaacctcccc gacgagacag aagcggcact caaggggggc tggctccaca ccggagacct
    11221 cgcccgccag gacgccgagg gcctgatcta catcgtggac cgcaagaagg acatgattat
    11281 ctcgggcggc ttcaacatct acgccagcga ggtcgaggcc gttctgacag cgcacccttc
    11341 ggtgggctca gccgcagtca tcggcgtgcc ggacagccgc tggggcgaga tcgtcaccgc
    11401 gttcgtggtc ccgcgaccgg ggcaacaggt cgacattccc gcgctccagt cgtacgtgaa
    11461 gcaggtcaag ggctcgatgt acgcgcccaa gaaggtcgta gtcgtggact cacttcccgc
    11521 cacgccggtg ggaaagatcg acaagaagcg cctgcgcgcg ccgttctggg ccgactcgac
    11581 ccgcaatatc cactgaccat cccgatgccc ttcccacggc cattcacgaa aggcacgcag
    11641 tgtgaacgta ccgccagccc gactgatcga ctttcactcc cactggggca cagagcgagg
    11701 atggaaggga agcccgtacg agactgccga ggaccgcgag gccctgcggg gctacttcaa
    11761 gtggggcatg agcttcgtca gcgacgagga gcaggccgtc cagtttcgcc gcgccaacgt
    11821 caaggcgatg ctcgacttcg cgttcaccca caccatggac gccggtgcgc tacgcgacca
    11881 gcacgactac gccttcgact atgcgcgcaa gcaccccgac gtcgtactgg gcaactggat
    11941 cggcatcgat cccacgcaac cggctcacgt caaggaactc gaacgctgcc tgagcgaggg
    12001 gacgggactc gtcggactga cggtccactc gttcacgccg gccgggacac ccgaccagcc
    12061 ggaatgggag acctgtctga acatgtgcat cgaggccaac cgtcccatcc tggtccatgt
    12121 cggcatgtcg gccaccgggg ccggcactcg cggaggcatg ggcatcacac tggagggctg
    12181 ccacccccgc tacgtcgacc gcgtcgcggc caagcatccc gatctgaacg tgatcgcggc
    12241 tcgggtggcg tggccctggc agtcggagat gatcgctgtc gcactgcaca aggcgaacgt
    12301 gtggatggag ctccacggtt ggtcgccgcg ctacttcccc gacgagctca agcgcgagat
    12361 cggtaagcgg ctgcgcaaga aggtcttctt cggagccgac tacccgatgc tcacccacga
    12421 gaggctggtc gaggagtggc gcgaggaagg cttctcctcc ggcgtcctcg atgacgtgtt
    12481 ctccggcaac gccgagacct tcctcacctc gatcggagtt cagtgatgga cgtcggactg
    12541 accggcaagg tcgccatcgt cggcggcggc agcgaaggcc tcggatacgc catcgccgat
    12601 cgtcttctga aggaaggcgc caacgtcacg ctcttcgcgc gacgcgcgga gaaggtcaca
    12661 gccgccgcgc aacagcttgc cggtacatac ggcgaggaaa aagtcctcgg gctgaccgcc
    12721 gactgctcgg ccgacaccga catcgagcgc gtcaccgcct cgacccttga gcggttcggt
    12781 ccagccgttc acgttctggt caccaacgac ggcggaccgc cgatccggcg catctccgag
    12841 ctcaccgacg aggtgtggct gaaggcattc gagcgccact tcttctacgt ggtgagatct
    12901 gtgcgggcca ccttgccgca catgaccgcc gaaggcggca gcatcctcaa cgtggtctcc
    12961 ggcgtcgtcg agcgcccggc ggtcggcatg gcggcgtccg tcggcgtgtg gtcggcggtg
    13021 atcggctacg ccaagaccct cgccttggag gtcgccaggc agaacatcaa cgtcaacacc
    13081 ctgctgtccg gattcttcga caccgcccta ctgggcggaa tgctggaacg gcagccacag
    13141 ctgtccaaag ccggcctcgg gaacggggta ccgatgggac gcatcgggga gccccgtgag
    13201 ttcgccgacc tggtcggtgc gctcgtgtca cccaacttgc gattcgtcac cggcgcggtg
    13261 atcccggtcg acggtggcgc cggcatcggc atgggcgcga gcttcgactc gccgacttcc
    13321 aagtgaggca ctgttcatga aacggaccat gaagatctcg acgatgctcc cctacggcac
    13381 cgacccgcgc gaggccgctg accacatcat tcgactcgag gccgccgggc tcgacaccgt
    13441 ctgggtcgcc gaggggtacg gctacgactc gccaaccctg atgggctacc tggcggcccg
    13501 cacctcaagc gtggagatcg gcgcagccat cctcaacgtc tactcccgca ccccgaccat
    13561 gctcgcatcg accgcggccg gcctcgacag cgtgtccggc ggccgtgcca tcatcggcct
    13621 cggcgcctcc aacccgaaga tcatcgaggg gtggcacggc atgcccttcg tacagtcgac
    13681 cggccgtacc aaggagaccg tcgagatcat ccgcgcggcc ctgcggcgcg aggcggtcga
    13741 ctacagcggc cgctccttcg agatcccgct cccgcccggc cagggcaccg gccttggtga
    13801 gccgctgaag atcatgacca agccgctacg tccctcggtt ccgctttaca ccgccgcgct
    13861 gggaccgaaa tcagtcgagg gcgcggcgga gtacgccgac ggctggctgc ctttcctgta
    13921 ctcccccgag ggcgccgccg gggtatgggg cgacgcgctt gccgcgggaa ccgcgaagcg
    13981 ctccgagaac ctcatgcccc tggaggtcgt cgccggtggc atcgtcgcta tcggcgagga
    14041 cgtgaaggag atactcggcc tcgcgcggcc gatactcgcg ctctacatcg gaggcatggg
    14101 cgcccgcggc aagaactttt tcaacgacct cgtccgacgc tacggctacg aagccgaggc
    14161 cgaggagatc caggacctct acctcgacgg caagaagaag gaagccgagg ccaaggtccc
    14221 attccaactt cttgaacagg tcaacctcgt cggcccagcc tcttacgtcc gggagcggat
    14281 cgaagccttc cgcgagtccg gcgtcaccaa tctccaggtg accccgaccg gcgacgaccc
    14341 cgccggactc gtgcgtcaac tcaaggagtg ggtggcctga cttctgcttc tgcccaggca
    14401 acaccccttg cagcgcttga cggttaatga ccccgaggtg gtggactccc cgcctcggga
    14461 tcgctgacgc gactcgcccc gtccagtcct gccgaagtcg agcaaccggt caaggacccg
    14521 gccccagcga cgggccccat cgcgcctacg acgaccggcg gatgcccata cctgtcagtg
    14581 tcaagccacc ctcgccgtgt gcgcctgcgc ccttatgtga tcctcaggcg cgagcaggat
    14641 ggcgaccggc caggtaatca gaccagttct cgccggccaa ggctgcgaag tgttccgctg
    14701 ttctcggctg gatgccgatt aggtcggaga tcagcaccgg tggcaggtcg gctagcctcg
    14761 cactttcacg aggcaggctg tccgcttggt gatcaagaaa gcagaaagtg cctctgacca
    14821 gcaagaatga ggattgcgga cggtccatga tccgggcaag atcctgctgg atgtcgcgct
    14881 cgcggtggcg ctgggcgggg actgcctggc cgatgtgggc atgtcgcggg ccgagccggc
    14941 cgtgttcggg ccggtggcct ccgacccgac ggtttcccgt gcagagggcg tcggcttctt
    15001 cggtgtgacc ttggagagca gcggccccgt ctttttcagc tctgtgccct cgtcccactg
    15061 ctcatcgtta ccagcggggg tacgtatttc gggtgcaggg ccttgctctc atgcgacgac
    15121 tgctgagggg gtggcgcgga tccgtgcgat gtcgcgcata ggcggcgcgc cgaacagtcg
    15181 cttgtactcc cgactgaact gggaagcgct gtcgtatccg acgtgacggc tggccgtggt
    15241 cgcgtcggcg tgtccgtcga ggatgagccg gcgtgccgcg tgcagtcgga gctgtttctg
    15301 gtactgcaac gggctcatgg ctgtcacgga tttgaagtgc tcgtggaagg acgagcggct
    15361 catctgggcc gccttggcga gttcctcgat cgacagcggc tcagcgtagt tctcgcggat
    15421 ctgacggccg ggctcacatc gacgcctacc tcgaaaccaa ggccgtgtgg atgagtgggg
    15481 gctcgcgatg accgcagagg cggacggcaa ggtgatcgcc ctgttcggcg caggtcccgg
    15541 gctgggagcg gctgtggcac accgcttcgg gcgcgagggc tatcgtgtcg cgctcgtcgc
    15601 gcgccgcggc gagacattgc gggtgctggc agaggagttg gccggcgagg gcgtggaggc
    15661 ggttcccttc cccgcggatc tctcccgcag cgaggcgatc ccagatctcg tggccgacat
    15721 caccgcgcgg ctggggccca tcggagctgt gtactacgcg cccatcaccg gtgagtctcc
    15781 cttccttcct gccaccgagg taaccccgca gatcctggcc ggttatgtcg atctgtacct
    15841 gtacagcccc atcgcggtgg tcaatgcggt gctggccggg atgctgggcc gcggagacgg
    15901 ggccatcctg gtcgggcacg gcggcagcgc cgctcatccg gcgccgttcc gcagcggcat
    15961 cgggccgatc atgtccgcta cccggaacta cctgtactcc ctgcacggcg agctggcagg
    16021 gaaaggcgtc tacgtcggaa cggtcaccat cagcgcggtc atcctcggaa gtaccggtgc
    16081 ggcggcggtg gacaccgagt tgatcactca gctcggtctc ccgaccgccg agccctccga
    16141 cctcgccgac ctgttgtgga acatggccga cgcacgggac cgcgtcgagg tggcctggcc
    16201 agcgccaccg gagagccaga gctgaggcag gcggccgtcc ggtgggcgat gaccggctgt
    16261 ggtttccgtg cggaggtagt ggctcaatca gccggccgac gatgtgaccc tggagggagc
    16321 cgccctcaac ggagtcgttc atggtgctga ttacgtgcgg aagctcctgg cgtacgcgcg
    16381 gacgctgtac gagtaccagg acttcgagtt cgtcgggcga cacggtcccg gcccctcgcc
    16441 ttgaccgcca gtggccacgg accaggcaga accggacacc ggcggaggtc gctcgtcacg
    16501 tacaccaaaa agccgctcgt gtggacacga aaaaaggaca ccgggccggc gtcacgagat
    16561 atgtgacgcc ggcccggtat cacggatact cggcgacacc acatctgtga catacacggc
    16621 accggcgccg actgggctga tgccggcccg ctgctcgaga ttcgcgacca cgctggcgag
    16681 actgcgacac tggcctcccg ccccggtctc gtggtgatcg ccaccgccga caagaatctc
    16741 ggcactaccg agatgcgtca cgaaatggcg ctcctcgcgg gcgccagggc ggtcgaactc
    16801 tccgatctcc accactggtg gatggtggag gccccccagc gtgccgcgga gatcctcgaa
    16861 gacttctgga acgatcccgc tctttcctaa cagaaccggg caccccgtcg acaggatcag
    16921 agtctccgtt cacttctcaa cgcagagagc aaatggacgg gcccacgagc tccgggcccc
    16981 gtatgtctgc caaaatagcc aacctcatcg aggatctacc gcaaatccgt catgctcatg
    17041 ttcagcagcg gccagatctg ctgggcgtcg acggacgcct gtcccggtct gacgaggtgc
    17101 tgccccggtg accccggttg ctgaggctgg tggagcgagt gaccatgagg gaaaaccagc
    17161 cgttcccact acgaggggaa ggaatgcctt cgtctgagtc gtttgactac gtcatcgtag
    17221 gggctggtag cgccggatgc gtcctggcgg ctcgactcac cgaggatccc gcggcccggg
    17281 tgctcctgct ggaggccggc gctgaggaca ccgaccagaa catcaaggca ccggcggcgc
    17341 tcgggctgct cttccactcc ggggtcgact gggattacca gacggtcgag caggaggcgg
    17401 ccgggcgggc gttctactgg ccccgcggga agaccctcgg gggctcgtcc tcgaccaacg
    17461 tgatgctcta cgcccgcggc cagcgggacg actacaacag ttggcgggac gagtacggcg
    17521 ccacggggtg gggtttcgat gacgtccagc cgtacttcgt aagggccgag cggaacaagc
    17581 ggcacggccc gccctcccac gggaccgagg gcccgctcca cgtcgaggac cggccctaca
    17641 cccacgagct gtcccgcgcc tgggtggacg ctgccctggc ctgggggctg ccgccggtgg
    17701 aggacatcgc cggcgcctct ccgcagggcg cggggctcac tcaggtgacc tgccgggacg
    17761 gccggcggtg gtccaccgcg gacgcctacc tgcggcccgc gctcgaccgg gagaacctga
    17821 ccgtgcgcac gggggcgttg gcgaccagag tgatcatgga agggagcaag gccaccgggg
    17881 tcgcgtacct tcgcgacggt accgagcacg tggcccgtgc tggcggcgag gtcgtgttga
    17941 gcggcggcgt cgtcaactcg ccgcaactgc tgatgctctc cggcatcggc ccctccgacg
    18001 tgctcaggga gcacggcatc gatgccgcag tggtgctgcc cggggtgggc aggaacctcc
    18061 acgaccacgt cctgaccccg gtcgtgtggg agacccggga cagcagcgac atcatcgtcg
    18121 acctcctgac accggagaac ctccagcagt gggccgagac cggcggcggg ccgttcgcgt
    18181 ccaactacgc agaggcgatg gcctacctgt cggtgacgcc cggtgtgtcc cgccccgaca
    18241 tgcagctgac aggcgggccc accgcgttca tcctgagcgg gcaggagatg cctggccggc
    18301 cggtgttcac gatgaacgcc acgcaactac ggccgcgcag ccgcgggcac ctgaccctcg
    18361 cgtccaccga tccccgcgac catccgctga tcgatccccg atacttcacc gatcccgagg
    18421 acgaggccac gctcatccgc ggcgtgcgcg ccgtcatcga gatcggcgac caggagccgc
    18481 tggcggcgtt cctggaccgc ccctacctgc cggccggcac cgatctgagg gcgctggacg
    18541 acgcgacgct gtccgaccac atccgcacct ggagcggcac cgcctaccac ccggtgggca
    18601 cgtgcgccat gggcaccggc gaggcggccg tggtggatcc ggaacttcgg gtgcacggca
    18661 cggccggcct gcgggtcgtg gacgcctcgg tgatgccgac ggtcgccagc ggcaacatca
    18721 acgcccccac cgtcatgatc gccgagaaga ccgccgatct gatccggggc gttcccgccg
    18781 cctgagccca accgcggcgg gacctcgcgg caccgcgggc ggaacccgca cagcgcccgc
    18841 ggcgggggtt tcactcccgc cacggcgatg aacggttcga ggggcggttc ccggccccgg
    18901 cgccgtggcc cgggagcgag gcgtcgacgc gggtgacgcc ctcctccacg gcgacgacgc
    18961 tgttggcgac cgcgagggag aggttctggt gggcgtggat gccgaactct gtggcggggt
    19021 cgagaacgtc gcggtaggcg cggaaccgct cacggaggcc cgcggcaggc acgcggcatc
    19081 gggcctcgcc acgccggaag aaccgcgtcg caaggacgca gctggccgcc tccggcgcgg
    19141 tggcctcagt ggctgcgata cctgcgcgcc agcgtcaacg ccgccgtgcg cagcgcgggt
    19201 gccacgcggt cgacgcgcag ccggttaatc cggccggaca ccgagacagc ggcgatcacc
    19261 cggccgctgt cgtcccgtac ggggtgcgcc acgcagacga ggccgggcgc cgattcttcg
    19321 tattcacgcg cgattccctc ggtccgtacg cggccgagtt cgcgcgccag gaggccgcgc
    19381 atcacgatgg tgcgtggtgt gcgtcgctca agagggctgg cgagcaccgc gtcacggacc
    19441 tggggatcgg cgtgtgcgag caacgccttg cccagtgcgg tggcgtgggc cggcatccgc
    19501 ccgccgatcc gcgagggtgc caccggtgtg atccggctgg tcagcttgtc caggtacacc
    19561 acgtcagcgc cttggagcac ggcgaggtgg accgtctccc cgaatgttcg gtaaaggttc
    19621 tccaggtggg gccgggccgc atcgcgcagc ccgcgctgcc tgggcaccag ctgcccgagt
    19681 tcgaagacgc gcaaccccag cctgagcccg tggctgccgg tttcgagcat gcccaggtca
    19741 atcagttgcc ccgacagccg gtgcgcggtc ggcttgggca ggcctgctcg acgtgccagt
    19801 tcggacaggg atacatactc gtcatcttga tggaaggcgg acagtagggc gacagcgcgt
    19861 cccagcaccg aattgtgccc gtcgtctcgc tcagtggaac gcataactgg catccttcca
    19921 tcccccggga cgatcgtcga cagcgtgact tccgaggtcc ccgaaatatc ttggtcgggt
    19981 ctgcctgttt tcagcctcga tcagcatgga atgccggtcg gacatactga ccgccgcgac
    20041 ggttttcggt cctggcctgg cacataccaa cgaggaataa aaggagttcg gtgtgagcga
    20101 tctgacgctg ctggaacacc ccactgccgg ttcatacgcc ccgctgatta tcaccggtaa
    20161 cctcgccttc gtctccggcc acatcggatg gcgcgacgac aaggcgtccg tggtgggcgt
    20221 cgtcggccgt gacctgtcgg tggagcaagg caaggtggcg gcacgcgacg cggcactcgc
    20281 ggcgctgggc acgctcgacc gggaggtcgg cctggaccgc gtcgcctccg tggtccgact
    20341 gttcgggatg gttcgtgcgg atcctgaatt cgcgcagcat cccgcggtta tcgacggagc
    20401 gtcccacgtc cttctggacc tgctcggcga ccgcggacgg cactcgcgat cggccgtcgg
    20461 catgacgtcg ttgcccttcg gcgcggccgt cgagttggag ttggtggtgt gccttgacca
    20521 gtgacgtgaa caccggaccg tcccagagcg tgcttcacgc accccagccc gtccccccgc
    20581 agaaccggcc cgtgacaccg gcgctctttc agacggcggc gtggcagttc tccgatctgg
    20641 gtcaaatgga cggcatattc agcggccaga tcgcgggtgc gcaatacggc accgtcggta
    20701 tgccgaacaa tctcgcgctg gaagcggcac tcggccgact ggagggtgcc gaagccagcg
    20761 tggtcgccaa cggcggtatg gctgccattg cggggaccct gctcaccctg ctcggccccg
    20821 gaaagcgggt catcgtcggc agggagggtt tcagttggac acttgggctg ctacgcgatc
    20881 tggagcagtg gggccttgag cacacggcaa tcgacctgac ggacctggat gccgtcgaag
    20941 cggcactgcg tgacgagacg catctcgtgt tcgccgaaac cgtgtcgaac ccccgactgc
    21001 gtgtgcccga cctgagtgct ctgagcacgc tcacgcatgc ggcgggcgcg cttttggccg
    21061 tcgacaacac cttcgccacc ccgttccact gcactccgct cgcgttgggt gccgatctcg
    21121 tcatcgagag tgcgacgaaa ttcctgggcg ggcactcgga tgccgttctg ggcgcggttt
    21181 caggaaaaac gaacctcatt gagcccattc gcaggcgaat ggtgcgtctg ggctcgatcg
    21241 ccgcccccat ggacagttgg ctcatccagc gtggcctcat gacctttgtg gtgcggatgg
    21301 agcgggccag tcgcacggcg gcggccatcg cggagtggct ggccgcgcac cccgccgtcg
    21361 gcagggtctt ctaccccggc ctcaccagtc atcctgatca ggaggtggcc gccaaggtcc
    21421 tcgaccgggg cttcggtgcg atggtcacct tcgagctcgc tcccgacttc gaaagggtga
    21481 acgagttcac tcgcaggctg catgacatca cgctggtcca ctcgctcggg ggcacgcaga
    21541 cctcgctgtc gcacccggcc agctccagcc atcggctgct gtcggcggag gagctgtccc
    21601 aggtggggct ccacccggga gtgctacgca tgtcggtggg actcgaagag cccgatgacc
    21661 tcatcgccga actcgccacg gccctcggcg gctgacggcg gctgacggcg gctgacggcg
    21721 gcatcctccc accgctgtcc ggtcagggcg gccttctgat gtcaccgggc gccggcgggg
    21781 gccggtccgg tggaatcgcg tatcacgagg cggggtacga gggcttcctg ccgtcgcggc
    21841 gcgtcgggat cggcgatgcg ggcggcgagt acgcgcgcgg cgcgtctgcc gatctcggcc
    21901 ttcggagggg agacagcggt cagcggtacc tcgcacaggt cggcgacctc gtcgtcgtag
    21961 ctgatcacgg agaggtcgtc ggggacgccc aggtgtcggc gccgggcggc gctgacgagc
    22021 agggacgcct cgcggtcggc gaagcagagc acacccgtga tgccgtggtc cacgacccgg
    22081 tcgaggaagc ggtccgcgtc gcgagcggtc cagcgcggca gcgaggccgt gatcaccggg
    22141 tccggaccga ggccggctcg atccagagcc gtggacaggc ccgagcggat ctggggggcg
    22201 gtgtgcggac ttgatcgttc catgtagccg atgcgggtgt ggcccaagct cagcagatag
    22261 cgaagagcgg acagggtgcc ggctgcgtgg tgggtgcaga cgaactcgtg cagggtcgtc
    22321 ggcagggtca gtcctcgctc gacgagcacg gtggggacac tgagttcgtc ggggtccgag
    22381 ggccagaggt cggcgcggtc gtggctgagc gcgggcacca ggatcaggcc cgtcgagccc
    22441 gccctgatca gctcgttgac ggcccctcgc tccatggcgg ggtcccagtc ggtgcagcgc
    22501 agcagcatcc gggagccgtg ctgggccagt tcacgctcga tgccggcgat gacgcgcggg
    22561 tagtagtagg tcagcgacga cacgaccacc ccgacggcgt agccggtctc cgacgcctgc
    22621 ggggaggaga cgtaggttcc cgatccttgc ttgcggtaga ccagcccctc ctggacgagg
    22681 aggtcgacgg cccgacgcac ggtgttgagg ctgacctgct ggtcctgtgc cagttcctgc
    22741 tcggtgggca gtttcccact gggccagcgc agttcggcga taccgcggcg cagttcgtcg
    22801 gcgaggcggc gggtcttgtg gccccgtgcc gcggtgcccg cgggagggcg tgaggaggtc
    22861 ttcgcctcac cctcgggccg tggcggcgtc cctccttcgg accgcagtgc ctcggcttcg
    22921 ggcctgagcg tatctcctcc ggaccggagc gcctcgggct cagaccgcag cgtctcgcgt
    22981 tcggaccgtt gcgtcgatgt cacaccgatg accttatcgg ccgtcacaac cggtctccgg
    23041 gcgtgaggtc gatagattca ttccaatgaa tctattgacg caaggaatga cttgggctca
    23101 cactcctcgg caagcgaagc acgacctcca ccacccccac ttcgaaccga ggtcctgtcg
    23161 tgtccgtctc cgcgtccctc ggcagaagaa gccgcctcac cgcggtcttc gtctgcgtcc
    23221 tgcttctcct gggtttcctg gccgatcgca cggctttcgg ggccggcacc ccacccggtg
    23281 cggcggccgc cgctagctac tacgtggatc ccgtcaacgg ctcgcccgcc aatcccggta
    23341 cgtccgccca gccttggaag tccttccagg acatcttcgc ccagggacgg acctacggct
    23401 ccggggacgt cgtctacctg cgcagcggga actacggtgc cgctgtagtc aacgggggtg
    23461 tctcctcggg gaaccggacg atcaaggccg ctcccggggc ggtgccccgt atgaagacac
    23521 tgcgcttcgc agccggggcc acgcactgga cggtggacgg cgtcctggtc tccccgcagg
    23581 aggccgacgg cacgtacacc accggcaacc tcgtgcagtt cgactccggt gcgaccaacg
    23641 acatcctcca gaactcgcag gtgcgcgcgg ccagtgacgc cgcggcggac acctggtaca
    23701 acaacgactg ggtgaaccgc agcggcaccg gcatcgtggt catcggaagc aacaaccagg
    23761 tcctgaacaa tcagatccgc aacgtgcgca acggtgtgat gctggaacgc acgtcgacgg
    23821 cgggcgccgg cgcgaccgga ggagtggtca ggggcaacag cgtgaaccac ttctgggagg
    23881 acgcctaccg ctgcaaggtc agcggctgcc tggtcgagta caactccgcc gtcaacagct
    23941 acgcggtggt gccgcccggc acggaggccg atccgcccca ccgggacatg ttccagagct
    24001 accgcggtga cggcagtttc accccggtga cgaacgtggt gctccgcggc aacgtcttca
    24061 tcagccgcat gggcacgcgc tactccaaga tccccttcca gtacaacggg aaatacacca
    24121 tccagggcct cggcgccttc gacggcccct actccaactg gacgatcgag aacaacgtgg
    24181 tccaggtcga ggtcggtctc gccatgggcc tgtacggcat gaacaacagc aggatcgtca
    24241 acaacacggt ggtgccgcgc tacccggccg ccgacagcga gatccgcctc accaaccaga
    24301 aggacggcac accgccgacc ggcgacatcg tccgcaacaa cctggcacac accttcaaca
    24361 ccgcggccgc cgccgatgcc cagcactcca acaacatcac ggtgggcacc tcctactcga
    24421 cctacttcgt gaactaccag tccggcgacc tgcacctgaa ggcgggcaac cccgcgatcg
    24481 gcgccgccac caacagggac gcgcccacga tcgacgccga caggaaggcc cggtccgcgc
    24541 cgtacgacgt cggggcctac gagttctgac gcctcgttgc cggtcaggcc gaactgttca
    24601 cggtgcacct gctccagtcg ccccgcggcg tcccgagcag gtgcaccgtg aacggcgtcg
    24661 gcgcatgtgc cctgccgtgc gagggacgcc cccacacgca ggatcgccac ctaccggcag
    24721 cggctcatcg tcgccgacct ggtcccgtca gctgggctta cccggcttcc agtcctggtg
    24781 cccgggcgtg ggtggcgtcg tccgtccgta tatccagctc ttgatgtacg aggtgaggtc
    24841 gcggcccgag acgaagaact ggtgtgtcag ctcgtgcacc atgggccgtg ctgtccggcg
    24901 cggcaaggac cggtcacgcc ttaccgcgca ccaccggcct gttcgttctc ggccgctggg
    24961 atggtgccgg tgcgggacgg tcgtgctgcg gcgctgtcgg ctgagggggt gtcgctgctg
    25021 cggcggcggg cggccagtgc ggctccggcc aggatcaaca cggtgccggt gatcgtgcgt
    25081 gtggtgaccg gttcggagag caggagcacg ccggaggcca cggcgacgac cggggcgacg
    25141 taggtgatga acgcggcgcg ggccgggccc tcggtggcga tcagggcgaa gaacgcggtg
    25201 aatccgcccg cggtgcaggc cacgcccaga ccgaggaccg cgagcaggac ccgggtggtg
    25261 acctggggag ccggttccgc gatcgcggcc gccgccagca gcgggccggc agccagcgtc
    25321 agcatgcccg cgctgacggt caggggcggc acgtcgggga agagccggtg caacagcacc
    25381 gcgcccaccg catagcaggc cgcagcggcg agcaccagca gcgcgccagc gcctgcgacg
    25441 gccacgccaa gcaggacgac gacaccgagg aagccgagag ccacaccggc ccacgccccg
    25501 cgcgccagcc gctcgcgctt cccccagaac aggcccaggg ccaggatgaa caacggctcg
    25561 gtggcgatca gcaccccggc gagcccggag ggcacggtgc gctcacccac cgcgatgagc
    25621 gtgaacggca gcgcgacctc catcacggcg agcagcagca gcggacgcca tcgctcacgc
    25681 aacagccggg gcaggccgcg tcgccacgcc accggcaaca gcaccagggc ccccagcgcg
    25741 acacgccccg ccaccacgct cgccggcccc atgccctcca gcgccacgct gatcaggagg
    25801 taaggcactc cccacagtac ggacgtgatc atgaacaaca agaggccacg gcggctcatc
    25861 agtactccac ggggtcgaag gggcgcccgg atcgggcacg cgcagaccgt atgcaaggac
    25921 ctctgagctc tggaatgcat accatgcctc tggagaggca ggaaacttgt caatcgttaa
    25981 gctgtgaggt gtgatcacgg catggcgact ctcgactcca ccgactggca gctgctcggg
    26041 ctgctacagg aagacgcccg gctcggtttc cgggaactcg cacgccgggt agggctcagc
    26101 ccgccggccg tggccgcccg cgtccggcgc ctggaaagtc tccaggtgat caccggctac
    26161 ggagcccgcg tcgacccggc caaggccggt tggcccgtcc aggcattcgt ggtgctgtcc
    26221 accacaggcg tgcgccagtc ccaccagacc gcccacatcg cgcaggccgc gccgcacatc
    26281 ctcgaggacc accgcgtcac cggcaccgac gaccacatcc tgcgcgtggt ggcgcacgag
    26341 atcggggcgc tggagccact gattgaccag ctcaacgagc tcgggaagcc cgcgacgtcc
    26401 ttcgtcctct cctcacccaa ggcgtgggcc cccgtccccc cacccaccac atccgactga
    26461 caccttctcg gcggagcccg gacgcggcca tattccatcc ggcgattcgg agtccgccgc
    26521 ccaccagtca tcaccgatca cctcggctcg gcctgcggaa gcggtctgtt ggcccaacaa
    26581 ccagtcctgg acgccgctga cgaagtacct ggagcgtcgg tgttcataca cggtaggtgc
    26641 gcggcacatc ccggactgac gagcaacgcg ccgttgtctt actggatgtg ataactgagt
    26701 ttccgctgct caggcacggt tccgattgcc gtcgtgcgag cgttcgggcg atcagttcgt
    26761 cctcgacgat gcggaggtgg ccggtggcgt cggtgcaaga tggccgccgc gacgctcgtc
    26821 gtgggcaggc ataccggtgg attggcgtgg agtagccagc acaggggccg atgcgccaga
    26881 ccggacagcc gtacagggcg gccgctgcct gacgttgctg gggtgtgatg ctgaggcgct
    26941 gctcccgctg ttgggggatc ttgaggaggc gctgggggat ttcatcgaag gtgtgcaggc
    27001 cggtggcgtc agccttgacc cgccggaggc ggcggtcgtt gaagaccacg gattcttcgc
    27061 cgtaccggca tgtggtgccg agtggttctc ccgtgaaggt gagttcgctg gcagtcggcg
    27121 ggatggccat ggattctcgg ggccgacgat gtcgagccat ttgtctcggt cctcggcggg
    27181 aacccacatg cgcgagtagc tgttcggatc ggcgggggtc gacggcttcg gcgggtgcac
    27241 tcttggcgta cggaccgtcg gggtcgttgt cacggccgtg gggcaggagc cagaaggcgc
    27301 ccggcggaag gttcccgaag cgcgcagcgc cccaagcgac ccaacgtcag gcattggcgg
    27361 agcggccacg ccgaccaatc ggcgggcccg acgcagccgc gcgagcaggg cccgtgtgcc
    27421 gtctgggtat cggggcgtgt atatgctgcg caggatcgta ggtacggacg ggagcggatg
    27481 cggcacgagc accagccagc acatgccgag gcgcgggggg acagtggcgc gatgtgtcgc
    27541 tttggtccag tcagagtcgg cccgggtcct gctggtgcgc tctggcaggc gcgggcgggc
    27601 aaagctggct ggggacgaga agcaagccga gcccggcggc cttccgggga tcaagaacgg
    27661 aagtacgcaa ctgctgcgcg cgatcgcgcg ggcctgccca ggacggccga tgccctcccg
    27721 ggccagcccg tcacccggca tcagccctgt cccccgtgac gccgtcggcg accgccgggg
    27781 gcagaaagcg caggagaagc atgaccacgg ctctgatcac cggcggtagc tccggtatcg
    27841 gcgaaggctt cgcccgacgg cttgcctccg agggacacga cctggtcctg gtcgcccgca
    27901 acaaggaacg cttggatgcc gcggccgctc atcttcgcga ccgctacggc gtccacgtgg
    27961 acaccatcga ggccgatctc accaccatgg acggctgctc ccaggtcgaa gaccgattgc
    28021 gcaatagcgc ggtggacatc ctggtgaaca acgcgggctt cggtcttccc gcgccgtatc
    28081 cgcgcagcgc gatcgcggat gaggagagga tgatcgacat cctgatccgg accccgttgc
    28141 ggctgaccta tgctgcgatc ccagggatga ccgaacgagg ccggggcgcg atcttcaaca
    28201 tagcgtctgt ggccggcctg ctacctactg gcacgtacgg cgcggccaag gcgtggctga
    28261 tccggttttc cgagtctctc cgccacgacc tcaaggggca cggcgtacgg gtcctcgctg
    28321 tggcgcccgg gttcacccgt accccaggtg cggcaggtat cccggtaccc cactggctct
    28381 ggctggaggt cgatcaagtc gtcgaccagg cgatgaaaga cctgaagcgg ggccggccgg
    28441 tgagcatcgc gggctggcac ttcaaaatgt acgaccaggc ggtccggcac ctgccgcgcc
    28501 ggatcgttgc aaccatggcc cggtcccgta agaggctgcg cggatagggg cggtttcggg
    28561 ggcgtcggct tgggctgttg ttgcagcggt gggtgctcca ggcgcggcgg atgaggctgc
    28621 gtacggtacg ccttcgagtg gcccttgttt ggaggtgctc gctccgcgag tcagcgcacg
    28681 gtcatcgtcc ggtcgtggtc acggcctgtt atggactcgg atgctgctat gaaggcttgt
    28741 aggagaggac ggtcgtctcc tcggcgggtg gccatcaaga tccggctcac ggtaggaggc
    28801 ccgtcgagtt cgagcctgcg ggcgcctgcg gggagcaacg tcgtgacgct gtagggggcg
    28861 atgctgacgc cgaggccggc cgcgacgaac atgatgatgg tgtgccagtt cgagcactcc
    28921 tgcgcgacct ggacgtcgat gccggcgttc cgcaacggct gtgtgttcaa gtcgaacgcg
    28981 tgagttcctg ctgaacgcgg gaacaggatc agcggctcag cggccagcgc ccttgcttcc
    29041 acccggtcac cccttgcggc
//
