LOCUS       NZ_CP015588            20846 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces alfalfae strain ACCC40021 chromosome, complete genome.
ACCESSION   NZ_CP015588
VERSION     NZ_CP015588.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces alfalfae
  ORGANISM  Streptomyces alfalfae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8625867)
  AUTHORS   Gu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2016) Institute of Agricultural Resources and
            Regional Planning, Chinese Agricultural Academy of Sciences, 12
            Zhong Guan Cun South Street, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04; Celera Assembler v. 8.0;
            GapCloser v. 1.12
            Genome Coverage                   :: 310.8
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 02:19:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,535
            CDSs (total)                      :: 7,444
            Genes (coding)                    :: 7,210
            CDSs (with protein)               :: 7,210
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 107 of 234
            Pseudo Genes (incomplete)         :: 177 of 234
            Pseudo Genes (internal stop)      :: 26 of 234
            Pseudo Genes (multiple problems)  :: 73 of 234
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:53:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8070064
            Orig. end                         :: 8090910
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015588.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="33"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20846
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20846
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10846](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10846
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            236..828
                     /locus_tag="A7J05_RS38395"
                     /pseudo=""
     CDS             236..828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548573.1"
                     /locus_tag="A7J05_RS38395"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRGVATGTGDRSRPRAALPALCATHIVSRGIAYCAFPVRNPRITT
                     ATGRPAGATTAAFSLGLAVSARAGIRVRRTLDRRGPRAVMTTGPSSGRSVRSSPWRSWP
                     ARSGATSPSSRPPPSPTAGAPPTMAASPDSSRHRPRPPRPSRRSPASPWPSPSAATAPS
                     SSSSPPSRWPPYSSSPGRFRLTDPADASVLTAAG"
     gene            895..1470
                     /locus_tag="A7J05_RS35365"
                     /old_locus_tag="A7J05_34590"
     CDS             895..1470
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007504155.1"
                     /locus_tag="A7J05_RS35365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34590"
                     /product="ATP-binding protein"
                     /protein_id="WP_076687943.1"
                     /transl_table=11
                     /translation="MIVWLNGTHGAGKTTTGALVRQLIPDSRVFDAEKVGETLMDITPG
                     LPWTGNFQDWPPWRPLVVETARHVLDYTGGTLVIPMTVLVEQYWREISSGLAQHAIPVR
                     HFVLHADQDTLRGRIAGDTVLGPDSPFRLQYLEPYAEAAATWLHAEAEVVDTTHLTPGQ
                     TAQRIAEAVQNRANGPSGGPPDQGVGST"
     gene            1553..2791
                     /locus_tag="A7J05_RS35370"
                     /old_locus_tag="A7J05_34595"
     CDS             1553..2791
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487627.1"
                     /locus_tag="A7J05_RS35370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34595"
                     /product="aromatic acid exporter family protein"
                     /protein_id="WP_076689772.1"
                     /transl_table=11
                     /translation="MPDVSAPVIKLVRRTTEPVAAQTLRSTAAAVISFGVALMVLPPRP
                     APLTAPLTALLVVQVTLYATLTTGIRRVNAVVVGVLIAIGFTTLVGLTWWSLGLTIFTS
                     LIIGRFVRVNEFVPEVAISAMLVLGVSQATSAAWHRVLETLIGAGVGLLFNLLFAPPVW
                     TQSAGASIDGLARAMGRMFRTMGAEIAEGPIPFPRAAARLHEARRLDHDIVEVDASLRQ
                     AEESLRMNPRVREGLLSRVVLRTGLDTLEICAVVLRVLTRSLTDLAKFRRREALFPPDV
                     SAGLHELFEQMAEAIENFARLITSQVTANAEQAEERLTATLAASRITRDRVAEMLLRDV
                     QEYPRQWQLHGALLAEIDRILDELDLDKRTERLMQELDRHSAELSERHPRLAALRRRLR
                     GQSGTERRPVVEA"
     gene            complement(2799..4697)
                     /locus_tag="A7J05_RS35375"
                     /old_locus_tag="A7J05_34600"
     CDS             complement(2799..4697)
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330268.1"
                     /locus_tag="A7J05_RS35375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34600"
                     /product="alkyl sulfatase dimerization domain-containing
                     protein"
                     /protein_id="WP_076687945.1"
                     /transl_table=11
                     /translation="MTHTSQDHDSPADGPDDAEDFADAARGFIARLEPGAVHDATGRLV
                     WDADAYAFLEEDCPPTAHPSLWRQSRLVARQGLFEVVPGVYQVRGLDLSNITFIEGRHG
                     VIVVDPLISTEVAAAALSLYRTHRGERPVTGVVYTHCHVDHFGGVRGIIGPAEAASGRV
                     PVIAPAGFLEHAAGENVMTGPAMGRRSGYMYGAALPKGPAGQIGCGLGQTTSLGGISLI
                     APTLDVTATGQTETVDGVRLVFQLTPGTEAPAEMNFHLPDLRVLCVAENACHTLHNVLT
                     LRGALVRDPSAWARYLTETLALFADDTDVVFASHHWPTWGQDRAVRFLEEQRDAYAYLH
                     DQCVRLINAGRTGAEIAEELRYPPALERAWHVRGYYGSLSHNAKAVYQRYMGWFDGNPA
                     HLWQHPPREGAERYVAFMGGADAVVDKARASFEAGDLRWTAEVLSHVLLARPEHAAARA
                     LQASAFEQLGHGAECGPWRNFYLMGAMELREGVRGTPSRGAPDIIAALTVEQIFRSMAV
                     RINGPRAAAAGRILLRWEITAPEPAPGSPGTAETWTVLLSNGALTPMRGGAPRGEDPDV
                     TLRLPRTVLDAVMSRATTFADAIARGDATVEGDVRTLLTFGSLTDRPDTRFPIVTR"
     gene            complement(4738..5916)
                     /locus_tag="A7J05_RS41530"
                     /old_locus_tag="A7J05_34605"
     CDS             complement(4738..5916)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330269.1"
                     /locus_tag="A7J05_RS41530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34605"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_076687948.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.4e-15, bitscore:
                     55.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2e-18, bitscore:
                     65.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.9e-40, bitscore:
                     135.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFSFRPTYDDPQLAGLVDRLRTYLDGELAGYERERGITHETRLT
                     RADLEPVWRRSRELGFYGIHLPEEYGGQALSNVRLAALKEEISACGRVLGHSVLGDMGG
                     PLRAGDILKYATEHQLTTYLLPLVRGERACCFSLTEADAGSDVRSMTTTATPDGDGYRL
                     TGHKVFSSAGPFADFAIVVARTAGTENSFSAFLVDLDSPGCRVAEGATPMSGEHIESDI
                     ILEDCHVPAANLLGEQGQGLKIALGRVTNNRLLHCPTAIGAARRALHLTRDRALTRKAA
                     GGRLLMEMQSIQHKLADMATELYAARSMTYAALAALDGGSDVRAEAFMCKLFVAESAFR
                     ILDQAVQIHGKDGLTQGNEIEYLFRKMRMFRVLTGTSEIQRNGIAKSLVTLA"
     gene            complement(5954..7609)
                     /locus_tag="A7J05_RS35385"
                     /old_locus_tag="A7J05_34610"
     CDS             complement(5954..7609)
                     /NRPS_PKS="Domain: AMP-binding (7-448). E-value: 3.4e-96.
                     Score: 314.3. Matches aSDomain:
                     nrpspksdomains_A7J05_RS35385_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387884.1"
                     /locus_tag="A7J05_RS35385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34610"
                     /product="AMP-binding protein"
                     /protein_id="WP_076687950.1"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-102, bitscore:
                     340.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLGTYLTRSARHWPAHPALVCGDQTWSYDRLETAANRLASALRR
                     RGLRPGEAVASLAWNRAELVEVEFALYKAGLIRVPVNARLGRAEIEHILRDAPVRVLVF
                     DAAHREDALAAVEAARTDCLPVLLDTLVDEAPAAGGPVKGGAAVEGGVVDTGPADAGPG
                     AGPRPVPYADLLAEGDDGVVAVETAEHDPAVLNFTSGSTGALKAAVQTFGNRLANMRKT
                     LMSEDSRPGPHTRYLACGPITHATGMVLLAGVFGGATTHILPTWSAEAFFDTVERERIT
                     ATFLVPAMLNMVLAHPGAAERDLSSLTSVRVGGAPVSPQRLRDAVALFGPVVAQGYGLA
                     ETTSVVAGLSSADVLRGVTEDEELLRSCGRPAYDSEVRVVDERGGELPPREIGEVIVRG
                     PDCVSEYWHAPDLSAETFRDGWVHTGDLAFMREDGYLFLVDRKKDMIISGGFNIYSTEV
                     ETALYEHPAVQEACVIGVPDEKWGEAVKAVVVTRPGQHVGERELADFCALRLDRFKKPR
                     SVEFVTALPHNRNGKLDRKAVREPYWAGADRRVH"
     aSDomain        complement(6266..7588)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A7J05_RS35385_AMP-binding.1"
                     /evalue="3.40E-96"
                     /label="A7J05_RS35385_AMP-binding.1"
                     /locus_tag="A7J05_RS35385"
                     /protein_end="448"
                     /protein_start="7"
                     /score="314.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TRSARHWPAHPALVCGDQTWSYDRLETAANRLASALRRRGLRPGE
                     AVASLAWNRAELVEVEFALYKAGLIRVPVNARLGRAEIEHILRDAPVRVLVFDAAHRED
                     ALAAVEAARTDCLPVLLDTLVDEAPAAGGPVKGGAAVEGGVVDTGPADAGPGAGPRPVP
                     YADLLAEGDDGVVAVETAEHDPAVLNFTSGSTGALKAAVQTFGNRLANMRKTLMSEDSR
                     PGPHTRYLACGPITHATGMVLLAGVFGGATTHILPTWSAEAFFDTVERERITATFLVPA
                     MLNMVLAHPGAAERDLSSLTSVRVGGAPVSPQRLRDAVALFGPVVAQGYGLAETTSVVA
                     GLSSADVLRGVTEDEELLRSCGRPAYDSEVRVVDERGGELPPREIGEVIVRGPDCVSEY
                     WHAPDLSAETFRDGWVHTGDLAFMREDGYLFLVDRKKDMIIS"
     CDS_motif       complement(6359..6448)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A7J05_RS35385_0001"
                     /evalue="9.00E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="A7J05_RS35385"
                     /protein_end="417"
                     /protein_start="387"
                     /score="14.9"
                     /tool="antismash"
                     /translation="PPREIGEVIVRGPDCVSEYWHAPDLSAETF"
     gene            7742..8338
                     /locus_tag="A7J05_RS35390"
                     /old_locus_tag="A7J05_34615"
     CDS             7742..8338
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387902.1"
                     /locus_tag="A7J05_RS35390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34615"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_076687952.1"
                     /transl_table=11
                     /translation="MAEDRRVRKTRKALRDALVELVIERGFTALSVEDITQRADVGRAT
                     FYSHFRDKDELFARVTADLLAELDDRLRPVVQDSAVGFTGKPILQMLRHARDERDLYRI
                     VLRGEGDGKPLRMFTDACARVAAQEFRGRSERNAVEPRIDPELLARAWVGEQVAVLQWW
                     VEQDAPPMPAEEVVRMLLDLALRGRYWATGFDTPA"
     misc_feature    7760..7776
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     gene            complement(8305..9678)
                     /locus_tag="A7J05_RS35395"
                     /old_locus_tag="A7J05_34620"
     CDS             complement(8305..9678)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038407.1"
                     /locus_tag="A7J05_RS35395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34620"
                     /product="MFS transporter"
                     /protein_id="WP_076687954.1"
                     /transl_table=11
                     /translation="MPRSTEIAPPASPPRPGHVPPRPERRAWLVLVMIVVFMMISYADK
                     AVLGLAAVPLMEELGIGKSTYGLISSSFYLLFSLSGLVVGFSSGRISSRALLLAMAALW
                     AVAQLPVLLVAAVPSLIAGRVLLGMAEGPAASMSMHALYKWFPTGRRGLPSALQIGGAA
                     LGTAVSAPLLTWLIVDHGWRSAFVALTLVSAAWCLVWPFVGQDGPFGEERKPVRGASRP
                     PRAAGPPLRALLTNGTVTGGILSAFGSHWALALSSAWLPVYLQTQMDMTATGASSVVSG
                     VSVVSLALLLSVPAYVDRLKRRGVSSRRADGIPQGMAVLVAGGALALLPFAAGGPVQLL
                     LIAVAFGCHAVALPLHYVTTATVVPDGRRGAVFGVVAASGTLPGLFVPYLTGHLVDGAA
                     TEATGYTAAFLLSAGVMAVCGLLAIATIHPERDARRLNPAGASVPAPRQAGVSKPVAQ"
     misc_feature    9728..9745
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(9776..9787)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.54"
                     /tool="antismash"
     misc_feature    complement(9783..9801)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     misc_feature    9943..9957
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            10001..10846
                     /locus_tag="A7J05_RS35400"
                     /old_locus_tag="A7J05_34625"
     CDS             10001..10846
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="A7J05_RS35400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34625"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_079250269.1"
                     /sec_met_domain="CDPS (E-value: 3.7e-70, bitscore: 234.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVTMAGEVAARASALPFGASSERLVRRGDHALFGVSTGNSYFS
                     CRRLAEAVAWAVERFAVVDVVHADVALQATLEAFGYEPAAARRSATKQLRGVRRRIDGA
                     LKHVGASAERVRSRPLSDFLDQPGYQEVRARARAALRDDLEMRSVRDDTAFRFLAERLR
                     PDGLPAPAQVQAALAYVDAELPFFLDTPRILGVASSVHCYHSVLPLGRLLFGGRPKGPH
                     DAGPHHRQLPGSAARSGGAPAGSATSARAPPAPTRRGRGRVKWTGRRATMRRRARSSPS
                     "
     gene            10843..12081
                     /locus_tag="A7J05_RS35405"
                     /old_locus_tag="A7J05_34630"
     CDS             10843..12081
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377493.1"
                     /locus_tag="A7J05_RS35405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34630"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_076689774.1"
                     /transl_table=11
                     /translation="MTAKRRPRSVTSDRELRLWRVGRALTLAFVAAILVAGGVFYGLVV
                     LLDFQEIDSTTKLDAKTLFDLVKLSFGVVAGAGALVALVVAYRRQRVDEAGAHRDATRL
                     HTERFSQAVDRLGSDSPAVRLGGVHALAGLADDAPDDNLRQTCIDVLCAYLQLPFTPDP
                     GSTEPAHQDEHHRYLALRKVRHTILGLIADHYRRPRGTHRSWQGCDLDLTGVTIDCDMD
                     FSDAVFSGGAVNLGRAVFSGGVVSFTRAKFCGGAVYFGDAEFSGGSVHFSGAVFSGGTV
                     HFGDAVFSGGAVYFSGAVFSGGTVHFGDAAFSGSSVHFSDAVFSGGAVHFGDAVFSAGT
                     VNFRGAIFSGATVNFRDTVFSSGAVYFSGAVFSGGAVYFTRATGPAPNGLATAVGTPAP
                     ATVVLASVWLPGG"
     misc_feature    12193..12207
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            12515..13417
                     /locus_tag="A7J05_RS35410"
                     /old_locus_tag="A7J05_34635"
     CDS             12515..13417
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004939063.1"
                     /locus_tag="A7J05_RS35410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34635"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_237283483.1"
                     /transl_table=11
                     /translation="MSRELGVSEKEIRDCLDKLADLSMLSLPTGDDVLPVPVHPEVGLA
                     AHIHRREAEIEAQQRELAVARAAAADLAAAYAASQAGRGGRLETLSGMAEVRMRLTELS
                     RHAREELLAFMPGGALSQAALDASRPLDEQSLASGVRLRTVYLDSVRNDRATIEYARWL
                     STLGGQVRTSPMLPLRMLVVDRACAVLPLDPEESSLGAVVVRAPGVVAALVALFETLWE
                     QSAPLDGRALAGGDVEAPTPQESALLSLLAQGHTDEVAARKLGLSLRTVRRMMAVLTAR
                     LGARSRFEAGMLAARVGWI"
     gene            13580..13852
                     /locus_tag="A7J05_RS35415"
                     /old_locus_tag="A7J05_34640"
     CDS             13580..13852
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A7J05_RS35415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A7J05_34640"
                     /product="hypothetical protein"
                     /protein_id="WP_123985642.1"
                     /transl_table=11
                     /translation="METARVPGCAVEHVYEAVLPHRSRVGVLFVTAASPEAAGYGVLLA
                     VRGLLRRTEDHDQVLLRAPGPSEPALCHGIVTMPADAPLREMPVG"
     gene            14146..14316
                     /locus_tag="A7J05_RS40075"
     CDS             14146..14316
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A7J05_RS40075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162933607.1"
                     /transl_table=11
                     /translation="MAPRLAVLLTACAAAAATVLPVVSAHEGPAAGQATVTSAAPAPDV
                     ADATPLTWAWD"
     gene            14431..15468
                     /locus_tag="A7J05_RS35420"
                     /old_locus_tag="A7J05_34645"
     CDS             14431..15468
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550853.1"
                     /locus_tag="A7J05_RS35420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34645"
                     /product="asparagine synthetase A"
                     /protein_id="WP_237283484.1"
                     /transl_table=11
                     /translation="MSTYMTQTQPLTAPGTWRTPDEHFEVALTHPWYRLLLRLTDVMQR
                     ATVEFWAGRDVRAAYLPVTTGSISSPMGLGSDSVPVRIDLEGVPTYLADSMQFLLEYSC
                     RMWEKGSYYVMPSFRGEAPDPTHLCQFYHSEAELQGDLDAVMETVEAYVRHLGKAYLDE
                     MGPAIAEVAGDTAHIERLLSLKAFPRVTFSEAVDLLGDTPDLVTEVADGARALTRKAEA
                     ALMDKFGEFVWVTHFDHLSVPFYQAYEPGDTSRARNGDLLFGIGETVGAGERHATAEQV
                     REALAHHEVAEEDYAWYLRMRELRPMQTSGFGLGVERFFLWLLRHDDIRDLQMLQRVNG
                     RQINP"
     gene            15532..17145
                     /locus_tag="A7J05_RS35425"
                     /old_locus_tag="A7J05_34650"
     CDS             15532..17145
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="A7J05_RS35425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34650"
                     /product="radical SAM protein"
                     /protein_id="WP_103557561.1"
                     /sec_met_domain="PF04055 (E-value: 2.7e-20, bitscore: 72.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGLGPTLKNSDYLATTMLDRQSGDANTAAYLKGTDLEDFGLRRL
                     GFRHNGTDYPLLRPRYYNVPHLTTFAVQEILERAGHHVDTYDATNLWTDDLPAPAPQGD
                     YRAALLSTSFIWTDRDLRHAVQWISATYPGIPIVLGGQYSNLKYTSLMRSIPEIDYIVR
                     GDGEEALPGLLTALEKGSDPETVPNLVYRHSRELLGYRMSPFEYLDLDAFPSPSPKGQW
                     RVIPYESMRGCPFSCKFCSFPAASPKWRYKSAQKIADDWRRYADENGASYISAMDSTFT
                     VPPTRLRELMRLLPDVGVGWEGYSRANVLKTPELIAQLAASHCQFLSIGFESMSDSTLR
                     YMNKKVTRKDNLRAFRLLNEGGLGYRCSFMAGYPGERPEDFAETRDFLSEEYAGHFMLS
                     VFSISDETMPLWEDKEALRIEVHDPDDPDYSWSHIGMDVHTARRLNHTTLDRVRQVNDR
                     AVLRLWQADYQHLLMPQLGRWENIAVEKAVERIGMTPRDHSDPAAAVPQIRKQLDVLSR
                     YGVALYPRADVLSDRPLFHT"
     gene            17162..18466
                     /locus_tag="A7J05_RS35430"
                     /old_locus_tag="A7J05_34655"
     CDS             17162..18466
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="A7J05_RS35430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34655"
                     /product="MFS transporter"
                     /protein_id="WP_076687964.1"
                     /transl_table=11
                     /translation="MNSLRTLRQLPPRARRLIVLNAVNAAGSGVVLPLLVIYLHEMRGL
                     SLTAATGAVAATSVGALVGGPLAGWVSDRLGRVPAVWAALVCAALGAVGYALCDTPTTA
                     LAAGFVQGLGVGGAITWNALMADLVPEEHWPVLFSADFAMVNAMMGIGGLLGGLLAGMT
                     DSLAVFQALFLLDAASFLVTGWLVAREVRRRRSVEPPTGETPPEAAAADQPRSSYRAVL
                     GHRWLVALLVVVLVLFTVGYSQLNSGMPAALLADSRLGPTELGVLFAANTAAVVLVQAA
                     LIGRIKQVTAGVALALLAASWAAFWLLIWAVTGLSGGLVALLVGVIAMVVFAVGESLLA
                     ATGPTLVNSWADDSNRGRFNAAYGFVCSLGFTVGPLVSGRLTDDGHTTSMMLGFTAVLA
                     VLALITVRSRFLPRTPLSGLERTGHEDAAEEDARA"
     gene            18519..19778
                     /locus_tag="A7J05_RS35435"
                     /old_locus_tag="A7J05_34660"
     CDS             18519..19778
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014298.4"
                     /locus_tag="A7J05_RS35435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34660"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_076687966.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.6e-07,
                     bitscore: 29.8, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.1e-07, bitscore:
                     29.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRVLVCRWDPYILEALRAEGAEVALLFDTFEAAHFHVDEEVLK
                     TLPYVFRINSFDDMDELGQVATQLKNDGWLPDRVVSLSEFSQYGAGYLAQLLGCAQPTL
                     EMALNTRDKRAMKQAVRAAGVTCTDFVSLRTSEVAASVRRTAEEIGFPAVVKPCAGLGT
                     LGTSWVHSEEELTKLLTDLGADNTEHFLMAERPVSGDEFHVDAIWVDGRSKVLGIMRYL
                     RPRLAIETAGESNGSVLLPREEWAELYADVEEAHRRVNDALGIREGITHLEFFKQPGER
                     EVVFSEIASRFAGGGITATYRALGDDLRIAWIKSVVDPGRPAPYADGEPSRYVGWINLA
                     PSEAGRITAEPTQAEIDAFDYVLETVRPHGVGDDFSDPHPSAWCLHLIYGADSLEQFEE
                     RGRELEKALNSSFRTEPTDA"
     gene            19862..20707
                     /locus_tag="A7J05_RS35440"
                     /old_locus_tag="A7J05_34665"
     CDS             19862..20707
                     /NRPS_PKS="Domain: oMT (54-157). E-value: 1.6e-08. Score:
                     24.9. Matches aSDomain: nrpspksdomains_A7J05_RS35440_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="A7J05_RS35440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_34665"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_062768029.1"
                     /transl_table=11
                     /translation="MTEPTYEKEVRGYFADKAEAYDDVDLQPYWVLSDRLLADALREDV
                     ISALPEDFAFLDAGGGTGRWTSFFAQEAPRSTGVLFDLTREMIKVAEAKAAERGFADRV
                     RFVQGDLADVGETLRGESFDLAFNFHNVLGFVADPEQTIKDVAGLLKPGGLLVSFLPSV
                     WHTAWFNIAVGNIDEAEKALTRRGRFTDTMPDMHLYDVQRIEEMHAAAGLEIDALSGFP
                     NLIYPGYQETQLHGSTEQLVDILAGDDFERVLAMEKRVRKAPGIAGRGNNLFVVARRPA
                     "
     aSDomain        20024..20332
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A7J05_RS35440_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.60E-08"
                     /label="A7J05_RS35440_oMT.1"
                     /locus_tag="A7J05_RS35440"
                     /protein_end="157"
                     /protein_start="54"
                     /score="24.9"
                     /tool="antismash"
                     /translation="FLDAGGGTGRWTSFFAQEAPRSTGVLFDLTREMIKVAEAKAAERG
                     FADRVRFVQGDLADVGETLRGESFDLAFNFHNVLGFVADPEQTIKDVAGLLKPGGLLV"
ORIGIN
        1 ccgccgccat cgccggtgac ctcgacgcgg ccgaccgcgt cgaactcacc ctccccgaga
       61 ccggagtctg cggcggcgcc ggtctcttcg acgcccccga caccgcgcag accgacggct
      121 gctgcgcgcc gacgccgcaa ctcgtccagc tgagcgcccc cgccacggtc ggtgcgactg
      181 ccgaacaggc cccggcgggc ggctgctgcg gctcgtgacc ggcctgggca cccccatgcg
      241 cggcgtcgcg accggaacgg gggaccggtc gcggccccgc gccgccctgc ccgcgctctg
      301 cgccacgcac atcgtgagcc ggggcatcgc ctactgcgcc ttccccgtcc gcaacccgcg
      361 gatcaccacc gcgaccggcc ggcccgccgg ggccaccacc gcggcgttct ccctcggcct
      421 cgccgtctcc gcccgcgccg ggatccgcgt ccggcgcacc ctcgaccggc gcggcccgcg
      481 cgcggtcatg accacgggtc cgtcatcggg gcggtcagtc cgctcgtcac cgtggcggtc
      541 gtggccggca cggtccgggg caacctcacc ctcctccagg ccaccgccat caccgaccgc
      601 tggggcgcca cccactatgg ccgcctctcc ggactcctcg cgacaccgac cacgaccgcc
      661 acggccctcg cgccgttcgc cggcgtcgcc ctggccgtcc ccctcggcgg ctacggcccc
      721 ctcttcgtcc tcctcgccgc cctctcgatg gccgccgtac tcgtcgtccc ctggacggtt
      781 ccggctgacg gacccggccg acgcgtccgt gctcacggca gccggtgatg tcgggagggt
      841 cacccttttc cgctccgccc gtccccgcgg cccgcacgac gtaacgtcga gtgcatgatc
      901 gtatggctca acggcaccca cggcgcgggc aagacgacga ccggcgcgct cgtgcggcag
      961 ctgatcccgg actcacgggt gttcgacgcc gagaaggtcg gcgagacgct catggacatc
     1021 acgccggggc tgccctggac gggcaacttc caggactggc cgccgtggcg gccgctcgtg
     1081 gtcgagaccg cccggcacgt cctcgactac accggcggca cgctggtgat tcccatgacc
     1141 gtcctggtcg agcagtactg gcgcgagatc agctcgggcc tcgcccagca cgccattccg
     1201 gtccggcact tcgtcctcca cgccgaccag gacaccctcc gcgggcgcat cgcgggtgac
     1261 accgtcctcg gccccgactc cccgttccgg ctccagtacc tcgaacccta cgccgaggcg
     1321 gccgccacgt ggctgcacgc cgaggccgag gtcgtcgaca ccacccacct cacacccggc
     1381 cagaccgccc agcggatcgc ggaggccgtg cagaaccgag cgaacggccc ttcggggggc
     1441 ccgccggacc agggcgtcgg cagcacatga gccgagaggg gacgtggcat ggcgcgaggg
     1501 gttccagggg ccgaagtgtg atgaacggtt catgatcggg cacgtgaagg acatgcccga
     1561 cgtatctgcc cccgtgatca aactggtgcg gcggaccacc gaacccgttg cggcgcagac
     1621 gctgcgttcc acggccgccg ccgtcatctc cttcggcgtc gccctgatgg tcctgccccc
     1681 gcgacccgct cccctgacgg ctccgctgac cgcgctcctg gtcgtccagg tcactctgta
     1741 cgcgaccctc accaccggta tccggcgcgt gaacgccgtc gtcgtcggcg tcctcatcgc
     1801 catcggcttc accaccctgg tcggtctgac ctggtggagt ctcggtctga cgatcttcac
     1861 ttcgctgatc atcggccgct tcgtacgggt gaacgaattc gtgcccgagg tggcgatcag
     1921 cgcgatgctg gtcctcggcg tctcccaggc tacgtcggcg gcctggcacc gcgtcctgga
     1981 aacactgatc ggagccgggg tgggcctgct gttcaacctg ctgttcgccc ctccggtgtg
     2041 gacgcagtcg gcgggggcgt ccatcgacgg gctcgcgcgc gcgatgggcc gtatgttccg
     2101 cacgatggga gcggagatcg ccgagggtcc catccccttc ccgcgcgcgg ccgcccgact
     2161 tcacgaggcg cggcgcctcg accacgacat cgtggaggtc gacgcctcgt tgcgccaggc
     2221 ggaggagagc ctccggatga acccgcgcgt acgggaaggg ctgctgtccc gggtggtcct
     2281 ccggacgggc ctcgacaccc tggagatctg cgcggtggtg ctgcgggtgc tgacccggag
     2341 cctgaccgac ctggccaagt tccgcaggcg ggaagcgctc ttcccgccgg acgtgtcggc
     2401 cggcctccat gagctgttcg agcagatggc cgaagccatc gagaatttcg cccggctgat
     2461 caccagccag gtgactgcca acgccgagca ggccgaggag cggctgaccg ccaccctggc
     2521 cgcgagccgg atcacccgcg accgggtcgc cgagatgctt ctgcgcgatg tgcaggagta
     2581 cccccggcag tggcagctgc acggtgcgct gctcgccgag atcgaccgca tcctcgacga
     2641 gctggacctc gacaagcgca ccgagcgcct catgcaggaa ctggaccgcc actcggcgga
     2701 gctcagcgag cgccaccccc ggctcgccgc gctgcgccgc cggctgcgcg ggcagagcgg
     2761 caccgagcgg cggccggtcg tggaggcgtg aaagcgccct accgtgtgac gatcgggaag
     2821 cgggtgtcgg gccggtcggt gagcgaaccg aaggtgagca gggtccgtac gtcgccctcc
     2881 accgtggcgt cgccgcgggc gatcgcgtcg gcgaaggtgg tggccctgct catcacggcg
     2941 tcgaggacgg ttcgcggcag ccgcagcgtc acgtccgggt cctccccgcg cggcgcgccg
     3001 ccgcgcatcg gggtgagcgc gccgttggac aggagaacgg tccaggtctc ggccgtgccg
     3061 gggctccccg gcgccggctc cggtgcggtg atctcccagc gcaggagtat ccggccggcc
     3121 gccgccgctc gcgggccgtt gatccggacg gccatggacc ggaagatctg ctcgaccgtc
     3181 agggccgcga tgatgtcggg tgctccgcgg gagggggtgc cgcgtacgcc ttcacgcagc
     3241 tccatggcgc ccatgaggta gaagttgcgc cacgggccgc actccgcccc gtggcccagc
     3301 tgctcgaagg ccgaggcctg caaagcgcgg gccgccgcgt gctcgggccg ggcgagcagc
     3361 acatggctga ggacctccgc ggtccagcgc aggtcaccgg cttcgaacga ggcgcgggcc
     3421 ttgtcgacca ccgcgtccgc cccgcccatg aacgcgacgt accgctccgc cccctcgcgc
     3481 ggcgggtgct gccacaggtg cgcggggttg ccgtcgaacc agcccatgta ccgctggtag
     3541 accgccttgg cgttgtggct gagcgagccg tagtagccgc ggacgtgcca ggcacgctcc
     3601 agcgcgggcg gatagcgcag ctcctccgcg atctccgcgc ccgtacggcc cgcgttgatc
     3661 agccgtacgc actggtcatg gaggtaggcg taggcgtcgc gctgctcctc caggaaccgc
     3721 acggcccggt cctgccccca ggtgggccag tggtgggagg cgaacaccac gtcggtgtcg
     3781 tcggcgaaca gggcgagcgt ctcggtgaga tagcgggccc aggcgctggg gtcacggacg
     3841 agggctcccc gcagggtcag cacgttgtgc agggtgtggc aggcgttctc cgccacgcac
     3901 aggacgcgca ggtccggcag gtggaagttc atctcggccg gggcttcggt gccgggggtg
     3961 agctggaaga ccagacgcac gccgtcgacg gtctccgtct ggccggtggc ggtgacgtcg
     4021 agggtgggcg cgatcagcga gatgccgccg agcgaggtgg tctgcccgag accgcagccg
     4081 atctgcccgg cgggcccctt gggcagagcg gcgccgtaca tgtatccgga cctgcgcccc
     4141 atggccgggc ccgtcatcac gttctcgccg gcggcgtgct ccaggaatcc ggcgggagcg
     4201 atgaccggca cccggccgga ggcggcttcg gccgggccga tgatgccgcg taccccgccg
     4261 aagtggtcca catggcagtg cgtgtagacg acgcccgtca cggggcgctc accgcggtgg
     4321 gtccggtaca gggagagggc ggcggcggcc acctccgtgc tgatgagggg gtcgacgacg
     4381 atcacgccgt gccggccctc gatgaaggtg atgttggaca ggtccaggcc ccgcacctgg
     4441 tagacacccg gcaccacctc gaacagaccc tgccgggcca ccagcctgct ctgcctccac
     4501 agcgacgggt gcgccgtggg cgggcagtcc tcctcgagga aggcgtaggc gtcggcgtcc
     4561 cagaccagac gtccggtggc gtcgtggacg gcgcccggct ccagccgggc gatgaacccc
     4621 cgggcggcgt ccgcgaagtc ctccgcgtcg tcggggccgt cggcggggga gtcgtggtcc
     4681 tgcgaggtgt gggtcatggt gccgtctcgt ctcggtgcgg ggccggatgc ggcctcatca
     4741 ggcaagcgtc accagcgact tggcgatgcc gttgcgctgg atctcggagg ttccggtcag
     4801 gacacggaac atgcgcatct tgcggaagag gtactcgatc tcgttgccct gggtgagccc
     4861 gtccttgccg tggatctgga cggcctggtc gaggatgcgg aacgccgatt ccgcgacgaa
     4921 cagcttgcac atgaacgctt ccgcgcggac gtccgatccg ccgtccaggg cggcgagagc
     4981 ggcgtaggtc atcgagcggg ccgcgtagag ctccgtcgcc atgtcggcca gcttgtgctg
     5041 gatggactgc atctccatca ggagccggcc gcccgcggcc ttgcgcgtca gggcccggtc
     5101 gcgggtcaga tggagggcgc ggcgggcggc gccgatggcg gtggggcagt ggagcagccg
     5161 gttgttcgtc acccggccca gcgcgatctt caggccctgg ccctgttccc ccaggaggtt
     5221 ggcggccggg acgtggcagt cctccaggat gatgtcgctc tcgatgtgct cgcccgacat
     5281 cggggtggcg ccctccgcca cacggcaacc ggggctgtcc aggtcgacca ggaacgcgga
     5341 gaaggagttc tccgtgcccg ccgtcctcgc caccacgatc gcgaagtcgg cgaagggccc
     5401 cgccgagctg aacaccttgt ggccggtcag ccggtatccg tccccgtccg gtgtggcggt
     5461 ggtggtcatg gaccgcacgt cggagccggc gtcggcctcg gtgagggaga aacaacaggc
     5521 ccgctcaccg cgtacgaggg gcagcagata ggtggtgagc tggtgctccg tggcgtactt
     5581 caggatgtcc ccggcccgca gcggtccgcc catgtcaccg agcaccgagt gcccgaggac
     5641 tcgcccgcag gcgctgatct cctccttgag cgcggcgagc cggacgttgc tgagggcctg
     5701 gcccccgtac tcctcgggga ggtggatgcc gtagaagccc agttcgcgac tgcgccgcca
     5761 gacgggttcg aggtcggcgc gggtgagccg ggtctcatgc gtgatgcccc gttcccgctc
     5821 gtagccggcg agttcaccgt ccaggtaggt gcgcagacgg tcgacgagtc cggcgagctg
     5881 cgggtcgtcg taggtggggc ggaacgagaa ggtcatgtgc ggtctctctt gatgagtctt
     5941 gaggagggtg ttgtcagtgc acgcgtcggt cggcgccggc ccagtagggc tcgcgcacgg
     6001 ccttgcggtc gagcttgccg ttgcggttgt gggggagcgc ggtcacgaac tccaccgacc
     6061 ggggcttctt gaagcggtcg aggcgcaggg cgcagaagtc ggccagttcc cgctcgccga
     6121 cgtgctgtcc cgggcgggtc acgacgacgg ccttgaccgc ctcgccccac ttctcgtcgg
     6181 gcacgccgat cacacaggcc tcctgcacgg cggggtgctc gtacagggcg gtctcgacct
     6241 cggtgctgta gatgttgaag ccgccggaga tgatcatgtc cttcttgcgg tcgacgagga
     6301 acagatagcc gtcctcacgc atgaaggcca ggtcaccggt gtgcacccag ccgtcgcgga
     6361 aggtctccgc cgacagatcg ggagcgtgcc agtactcgct cacgcagtcg ggaccgcgca
     6421 cgatgacctc cccgatctca cgtggcggca gttcgccgcc gcgctcgtcg acgacacgga
     6481 cctcggagtc gtacgcgggg cgcccgcacg accggaggag ttcctcgtcc tcggtcaccc
     6541 ctcgcaggac gtcagcgctg gagagtcccg cgaccacgct ggtggtctcc gcgagaccgt
     6601 agccctgggc caccaccggc ccgaagaggg cgacggcgtc gcgcagccgc tggggcgaca
     6661 ccggggcccc gccgacgcgt acgctcgtga ggctcgacag atcgcgctcc gccgcgcccg
     6721 ggtgggccag caccatgttg agcatggccg gcacgaggaa cgtggcggtg atccgctccc
     6781 gttcgacggt gtcgaagaag gcctccgcgc tccacgtcgg caggatgtgc gtcgtcgcgc
     6841 caccgaacac accggccagc agcaccatgc cggtggcgtg ggtgatgggc ccgcaggcca
     6901 ggtaacgggt gtgagggccg ggccgggaat cctcgctcat cagggtcttg cgcatgttcg
     6961 cgaggcggtt gccgaacgtc tgcaccgccg ctttgagagc gccggtcgaa cccgaggtga
     7021 agttgaggac ggccggatcg tgttcggcgg tctcgacggc gacgacgccg tcatcgccct
     7081 cggccagcag gtcggcgtac ggtaccggcc ggggacctgc gcccggtccc gcgtcggccg
     7141 gtcccgtgtc gaccactccg ccctcgactg ctgctccacc cttgactggt ccacccgcgg
     7201 ccggtgcttc gtcgaccagg gtgtcgagca gtacgggcag gcaatccgta cgggccgcct
     7261 cgacggcggc cagggcgtcc tcccggtgcg ccgcgtcgaa caccaggacg cggacgggtg
     7321 cgtcccggag gatgtgctcg atctccgcgc ggcccagcct ggcgttgacc ggaacccgta
     7381 tcaaccccgc cttgtacagg gcgaattcga cttccacgag ttcggcgcgg ttccacgcga
     7441 gtgacgccac ggcttccccg ggacgcagcc cccgccgccg cagcgcggag gccagccggt
     7501 tggccgcggt ctccagccgg tcgtacgacc aggtctggtc cccgcagacg agcgcggggt
     7561 gcgcgggcca gtggcgggcg ctgcgtgtga ggtacgtgcc gaggttcatc gggcggctcc
     7621 agagcaggct gtaagtttcc ggacagtttg ttcagtaacg gtgggactgt caaggcttcc
     7681 gtacactgag ctgtcgcccc actccagggg ctcgggcacg gcaaggaaat gggggacggc
     7741 gttggccgag gacaggcgcg tccgcaagac acgcaaagcg ctgcgtgacg ctctggtgga
     7801 actcgtgatc gagcgggggt tcaccgccct gagcgtcgag gacatcaccc agcgggccga
     7861 cgtgggccgc gcgaccttct acagccactt ccgcgacaag gacgagctct tcgcccgggt
     7921 gaccgcggac ctcctggccg aactcgacga ccggctccga cccgtggtgc aggacagcgc
     7981 ggtgggcttc accggcaaac ccatcctgca gatgctgcgc cacgcgcggg acgagcgtga
     8041 cctctaccgg atcgtgctgc gcggtgaggg ggacggcaaa ccgctgcgga tgttcacgga
     8101 cgcctgcgcc cgcgtcgccg cgcaggagtt ccgtggccgc tccgagcgca acgcggtcga
     8161 accgaggatc gatcccgagc tgctcgccag ggcctgggtg ggggagcagg tcgcagtcct
     8221 gcagtggtgg gtcgagcagg acgcgccccc catgccggcc gaggaggtcg tgcgcatgct
     8281 gctcgacctc gcgctgcgcg gccgctactg ggccacgggc ttcgacacgc ccgcctgacg
     8341 gggcgccggg acggacgccc cggcgggatt cagcctccgg gcgtcccgct cggggtggat
     8401 ggtggcgatc gccaggagcc cgcacacggc catgacgccc gcggacagca ggaacgccgc
     8461 ggtgtagccg gtcgcctcgg tggccgcgcc gtcgacgagg tgaccggtca ggtacggcac
     8521 gaagaggccc ggcagggttc ccgaagcggc cacgacgccg aagacggcgc cacggcggcc
     8581 gtccggcacg accgtcgccg tcgtgacgta gtgcagcggg agggcgaccg cgtggcagcc
     8641 gaaggccacc gcgatcagca ggagttggac cggccctccc gcggcgaagg gcagcagggc
     8701 cagcgcgccg cccgccacca ggacagccat gccctgcggg atgccgtccg cgcgcctgct
     8761 ggacacgccc cggcgcttga gacggtcgac ataggcgggc acggacagca ggagtgccag
     8821 gctgaccacc gacaccccgc tgacgacgga cgaggcgccg gtcgcggtca tgtccatctg
     8881 cgtctgcagg tagaccggca gccacgcgct ggacagggcc agtgcccagt gggacccgaa
     8941 ggcgctgagg atgccgcccg tcacggtgcc gttcgtcagc agggcccgca gaggcggacc
     9001 cgccgcgcgc ggcggacggc tcgctccccg gaccggcttc cgctcctcgc cgaacggccc
     9061 gtcctgtccc acgaagggcc agaccaggca ccacgcggca ctgacgagtg tgagggccac
     9121 gaaagccgaa cgccagccgt ggtccacgat gagccaggtc agcagcgggg cggagacggc
     9181 ggtcccgagc gccgcgccgc cgatctgcag cgcggacggc aggccccgcc gcccggtcgg
     9241 gaaccacttg tacagcgcgt gcatggacat ggaggccgcg gggccctccg ccatgccgag
     9301 caggacgcgc ccggcgatca gcgagggaac ggcggccacc agcaggaccg ggagctgggc
     9361 gacggcccag agcgcggcca tggcgaggag cagggcgcgg ctggagatcc gtcccgagga
     9421 gaacccgacg accagcccgg acagactgaa caggaggtag aaggagctgg agatcagccc
     9481 gtacgtgctc ttgccgatgc ccagctcctc catcagcggc accgccgcga gaccgagaac
     9541 ggccttgtcg gcgtaactga tcatcatgaa gaccacgatc atgacgagga ccagccatgc
     9601 ccgccgttcg gggcggggtg gcacgtggcc gggtcggggc ggcgatgcgg ggggcgcgat
     9661 ctcggtggag cgtggcacgg gactccttgc ggcgcgtgac gcgtagtcgc gtaactgaac
     9721 aagctgtctg ttaacttgct gttggttcgg caacgtaaac ggctcggcag ggaaggtcaa
     9781 cggtttcgac gccgtcgcaa tgccgccgca acgccgaggc gacgcccggt tccgaagggt
     9841 gtgcggggcc ccgacagtgt cgcgagggcc gatgacggag cgtgaggcgc gcgctgggac
     9901 acagtcctgc tgagaactac tcagtgtcac gccttcaggg actggacaac atgttcgtca
     9961 ctgtacgtgg gtacgttgcc cggcatgcgc gaagagcctg atgcgaagag tcacgatggc
    10021 cggtgaggtc gcggcgaggg cgagcgccct gcccttcggg gcgagcagtg aacgtctcgt
    10081 ccggcgggga gaccacgcgc tgttcggcgt gagcacgggc aacagctact tcagttgccg
    10141 ccggttggcc gaggcggtcg cctgggcggt ggagcgcttc gcggtcgtgg acgtggtgca
    10201 cgccgacgtg gccctgcaag cgacgctcga agccttcggc tacgaaccgg ccgccgcgcg
    10261 cagaagcgcg acgaagcaac tgcgcggcgt gcggcggcga atcgacggcg ccctcaagca
    10321 cgtcggtgcg tcggcggagc gcgtgcggtc caggccgctg tccgacttcc tcgaccagcc
    10381 cggctaccaa gaggtgcggg cgcgggcacg cgcggcactc cgcgacgacc tggagatgcg
    10441 gtcggtcagg gacgacacgg cgttccggtt cctcgccgag cggctgcgcc ccgacggcct
    10501 gcccgctccc gcccaggtgc aggcggcact ggcctacgtg gacgccgagc tgccgttctt
    10561 cctcgacacc ccacggatcc tgggcgtcgc ctcgtccgtc cactgctatc actccgtcct
    10621 cccgctgggc cgcctgttgt tcggcgggcg gccgaaggga ccccatgacg ccggtccaca
    10681 tcaccgtcaa ctcccgggaa gtgccgcccg gtccggcggc gcgcccgcgg gctccgccac
    10741 gagcgcccgc gcacctcctg cgcccacccg acggggccgg gggcgggtca agtggaccgg
    10801 ccggcgtgca accatgcgcc gccgcgcccg gtcctcaccg tcatgacagc caagcgaagg
    10861 ccgcgttccg tcacgagtga tcgggagttg cggctgtggc gggtcggccg ggcgctgacc
    10921 ctcgccttcg tcgccgcgat cctggtcgcg ggcggcgtct tctacggact ggtggtgctg
    10981 ctcgacttcc aagagatcga ctccaccacg aaacttgatg ccaagacgct cttcgacctg
    11041 gtgaaactct ccttcggagt ggtcgcgggg gccggcgcgc tcgtcgccct ggtcgtcgcc
    11101 taccgccgcc agcgcgtcga cgaggcgggc gcgcaccggg acgccacccg gcttcacacc
    11161 gaacgcttct cccaagccgt cgacagactc ggctccgact cgcccgcggt gcggctcggc
    11221 ggagtccacg ccctggccgg gctggccgac gacgcccccg acgacaatct gcgccagacg
    11281 tgcatcgatg tcctgtgcgc ctatctccag ctgcccttca ctcccgaccc cggtagcacc
    11341 gaaccggccc accaggacga acaccaccgc tacctggccc ttcgcaaggt ccggcacacg
    11401 atcctcggcc tcatcgccga ccactaccga cgcccgcggg ggacccaccg ctcctggcag
    11461 ggctgcgacc tcgacctcac cggcgtcacc atcgactgcg acatggactt cagcgacgcc
    11521 gtcttctccg gcggcgccgt gaacctcggc cgggcggtgt tctccggggg cgtggtgtcc
    11581 ttcacccggg cgaagttctg cggcggcgcc gtgtacttcg gcgacgcgga gttctccgga
    11641 ggctcggtcc acttcagcgg ggcggtgttt tccggcggta cggtccactt cggcgacgcg
    11701 gtgttctcgg gtggcgcggt gtatttcagc ggggcggtgt tttccggcgg cacggtccac
    11761 ttcggcgacg cggccttctc cggcagctcg gtccatttca gtgacgcggt gttctccgga
    11821 ggagccgtgc acttcgggga cgcggtgttc tccgccggca cggtgaactt ccgcggagca
    11881 atcttctccg gggccacggt gaacttccgg gacaccgtgt tctccagcgg cgcggtctac
    11941 ttcagcggag cggtgttctc cggaggcgcg gtctatttca ccagggcgac gggcccggcc
    12001 cccaacgggc tcgccaccgc cgtcgggacg cccgctcccg cgacggtcgt ccttgcctcc
    12061 gtctggctcc ccggcggcta gggaggggga cggagggcag tcgttccgtc cgcttcgctc
    12121 cggcgacggc cggtgtcgcg gcccggctcc gccggatcgg cccagagtgg cccggatcgg
    12181 cacggatcgc cctgatcgat tcggccaggt ctcgacagaa gcggtggcac aggcgtatac
    12241 cacctgtcgg gaggaatgcc ttgctccggg ggagtgatca cgccagttca tggcggtgag
    12301 aagcgacccc gggtattttg gccgacatcg gtgtggccga tgcgtgaatc gggggaacat
    12361 gcagacaggt agtaaggtgc gcccacttgc gcccatatcg gaacagctcg cacctgaagg
    12421 ggacagttcg ctcgcgacgt tgatcgggca ggacgacctg tgtgtggccg ttttccgtct
    12481 cgtcgtctca gggccgcagc ggaccgtcga cgacttgtcc cgggaattgg gggtctccga
    12541 aaaggagatc cgcgactgcc tcgacaagct cgcggacctt tccatgctgt cgctgcccac
    12601 gggcgacgac gtgctcccgg tgcccgtgca cccggaggtc gggctcgccg cccatatcca
    12661 ccggcgcgag gccgagatcg aggcgcagca gcgcgagctg gccgtggcgc gcgcggccgc
    12721 ggccgatctg gccgccgcct atgccgcgag ccaggcaggg cgcggcggac gcctggagac
    12781 gctgagcggc atggccgagg tgcggatgcg gctcaccgaa ctcagccggc acgcgcgcga
    12841 ggaactgctc gccttcatgc cgggcggggc cctgagccag gccgcgctgg acgccagccg
    12901 gccactggac gagcagagcc tcgcctccgg cgtgcggctg cggacggtct acctggacag
    12961 tgtccgcaac gaccgcgcca cgatcgagta cgcgcgctgg ctgtccaccc tcggcggaca
    13021 ggtgcggacc agtccgatgc tgccgctgcg gatgctcgtg gtggaccgcg cctgcgctgt
    13081 cctgccgctc gacccggagg agtcctcctt gggcgccgtc gtggtgcggg cgcccggcgt
    13141 ggtggcggcc ctggtggccc tcttcgagac cctgtgggag cagagcgcgc cgctggacgg
    13201 gcgggcgctg gcgggcgggg acgtcgaggc gcccaccccg caggagagcg ccctgctgag
    13261 tctgctcgcg cagggtcaca ccgatgaggt ggcggcgcgg aagctgggcc tgtcgctgcg
    13321 taccgtacgg cggatgatgg cggtcctcac cgcccggctc ggggcccgga gccgcttcga
    13381 ggcggggatg ctcgccgcgc gagtcggctg gatctgagcc cgggcggcgg tcctcttgct
    13441 gccacggcca taagctgtca ccgctggacc gcccggcggc gaggctggac tggaatggtc
    13501 ggtggccgtg tacgccattc atgtagaagt gtcaccgcag tcgtccgcga cggccgcggt
    13561 gagcctgcgt caagtcgccg tggagacggc tcgtgtgccg ggctgcgcgg tggagcacgt
    13621 ctatgaggcc gtgctgcccc accggagccg cgtgggcgtg ctcttcgtga ccgcggcctc
    13681 cccggaggcc gcggggtacg gcgtgctcct ggccgtgcgc ggcctgttgc gccgcacgga
    13741 ggaccacgat caggtgctgc tgcgcgcgcc cggcccgagc gagcccgccc tgtgccacgg
    13801 catcgtcacc atgcccgcgg acgcccctct ccgggagatg cctgtcggtt agacctcgcg
    13861 agtgtgcccc gctccgcggg ccgcaccctg cggtgaagaa ccgctgactg cccgtcgact
    13921 gccctgtggc cgcggcccgt tgccgccgcc cgtggtcggc ggctttcgca tgcccgctca
    13981 cctgccatcc gcaaccgcac cccccacagg gccctttggt gccaacgcac cttgctgcca
    14041 tccgcatccc ttgcccggcg ggtagcgggg ccgaaaactg ttcgcaccga caggaaccgc
    14101 tgtgaccagc aggttctttc gcacgaccgt caggagatga gccacatggc acccagactc
    14161 gccgtcctgc tgaccgcctg cgccgccgct gccgcgacgg tcctccccgt ggtctccgcc
    14221 cacgagggcc cggcggccgg ccaggccacc gtgacctctg cggcaccggc ccccgacgtg
    14281 gccgacgcca cgcccctcac ctgggcctgg gactgaccgg ccccggtgcc gcagcgtgcc
    14341 gcgccgccga atgagcgagg cacagccgcc cggatccccg cggccggccc acatcgcacc
    14401 aaccccgcac cgatggtccg aggaggacac gtgagcacgt acatgaccca gacgcagccg
    14461 cttaccgcac cgggcacgtg gcgcactccc gacgagcact tcgaggtggc cctgacacac
    14521 ccctggtacc ggttgctgct ccggctgacg gacgtcatgc agcgggccac cgtggagttc
    14581 tgggcgggac gtgacgtccg cgccgcctac ctgccggtga ccacggggtc gatctccagc
    14641 cccatgggcc tgggcagcga ctcggtgccg gtgcgcatcg acctggaggg cgtgccgacc
    14701 tacctcgccg actccatgca gttcctgctg gagtacagct gccgcatgtg ggagaagggc
    14761 tcgtactacg tgatgccctc gttccgcggc gaggcgcccg accccaccca cctctgccag
    14821 ttctaccact cggaggccga gctccagggc gacctggacg cggtgatgga gaccgtggag
    14881 gcgtacgtac gccacctcgg gaaggcctac ctggacgaga tgggaccggc catcgccgag
    14941 gtcgcggggg acaccgcgca catcgagcgg ctgctgtccc tgaaggcctt cccccgggtc
    15001 accttcagtg aggcggtcga cctgctcggc gacacccccg acctcgtcac cgaggtggcc
    15061 gacggcgcca gggccctcac ccgcaaggcc gaggccgcgc tgatggacaa gttcggcgag
    15121 ttcgtctggg tgacccactt cgaccacctc tccgtgccct tctaccaggc ctacgagccg
    15181 ggtgacacgt cccgcgcccg caacggcgac ctgctgttcg ggataggcga gacggtcggc
    15241 gccggcgagc ggcacgccac cgccgagcag gtgcgcgagg cgctggccca ccacgaggtc
    15301 gccgaggagg actacgcctg gtacctgcgc atgcgggagc tgcggccgat gcagacctcc
    15361 gggttcggcc tcggcgtcga gcggttcttc ctgtggctgc tcaggcacga cgacatccgg
    15421 gacctccaga tgctccagcg ggtgaacggc cgccagatca acccctgaac ccccgacaag
    15481 tccccgccgc tccgtgccca cccaggagag tgcaccatcg acgtcgtact tgtgtcagga
    15541 ctcgggccga cactgaagaa ctcggactac ctcgccacca ccatgctgga ccgccagagc
    15601 ggcgacgcga acacggcggc ctacctcaag ggcacggacc tggaggactt cgggctgcgg
    15661 cgcctaggct tccggcacaa cggcacggac tacccgctgc tgagaccccg ctactacaac
    15721 gtcccgcacc tcaccacctt cgccgtccag gagatcctgg aacgggccgg ccaccacgtc
    15781 gacacctacg acgccaccaa tctgtggacg gacgacctgc ccgccccggc gccccagggc
    15841 gactaccggg cggcgctgct gtccacgagc ttcatctgga ccgaccgcga cctgcgccac
    15901 gccgtccagt ggatctccgc gacctacccc ggtatcccga tcgtgctcgg cggccagtac
    15961 agcaacctca agtacacctc gctgatgcgg tcgataccgg agatcgacta catcgtgcgc
    16021 ggtgacgggg aggaggccct gccggggctg ctcaccgcac tggagaaggg cagtgacccc
    16081 gagacggtgc cgaacctggt ctaccggcac tcccgggaac tgctcggcta ccggatgagc
    16141 cccttcgagt acctggacct ggacgccttc ccctcgccct cgccgaaagg ccagtggcgc
    16201 gtcattccgt acgagtcgat gcgcggctgc ccgttcagct gcaagttctg ctcgttccct
    16261 gccgcgagcc ccaagtggcg ctacaagtcc gcccagaaga tcgccgacga ctggcggcgc
    16321 tacgcggacg agaacggggc ctcctacatc tcggccatgg acagcacctt caccgtgccg
    16381 ccgacccggc tgcgggagct gatgcggctg ctgcccgacg tcggggtggg ctgggagggc
    16441 tacagccggg ccaacgtcct caagacgccg gaactgatcg ctcaactggc ggcctcccac
    16501 tgccagttcc tgtccatcgg cttcgagtcg atgagtgaca gcacgctgcg gtacatgaac
    16561 aagaaggtca cacggaagga caacctgcgg gccttccggc tgctgaacga gggcgggctc
    16621 ggctaccgct gctcgttcat ggccggctac ccgggggagc ggcccgagga cttcgcggag
    16681 acacgggact tcctctcgga ggagtacgcg gggcacttca tgctcagcgt cttcagcatc
    16741 tccgacgaga cgatgccgct gtgggaggac aaggaggccc tgcgcatcga ggtgcacgac
    16801 cccgacgacc cggactactc gtggtcccac atcggcatgg acgtgcacac cgcccggcgg
    16861 ctcaaccaca ccaccctgga ccgggtccgc caggtcaacg accgggccgt gctgcgcctc
    16921 tggcaggccg actaccagca tctgctgatg ccccagctcg gacgctggga gaacatcgcg
    16981 gtcgagaagg cggtcgagcg catcggcatg acgccgcgcg accacagcga ccccgccgcc
    17041 gcggtcccgc agatccgaaa gcaactggac gtcctgtcgc gctacggggt cgccctgtac
    17101 ccccgcgcgg acgtcctcag tgaccgcccg ctcttccaca cctgacagga ctcgaccccc
    17161 catgaacagt ctgcggacgc tgcggcagct cccgccccgt gccagacgcc tgatcgtgct
    17221 caacgcggtc aacgcggccg gcagcggcgt cgtactgccc ctcctggtca tctacctgca
    17281 cgagatgcgc ggcctctccc tgaccgcggc caccggcgcg gtcgccgcca cctcggtggg
    17341 cgcactggtc ggcggcccgc tcgcggggtg ggtctccgac cgcctcgggc gggtgcccgc
    17401 cgtctgggcc gcgctggtgt gcgccgccct gggagccgtc ggctacgcgc tgtgcgacac
    17461 ccccacgacg gcgctggcgg ccggattcgt gcagggactc ggcgtgggcg gggccatcac
    17521 ctggaacgcg ctcatggccg atctggtgcc cgaggagcac tggcccgtgc tcttctccgc
    17581 cgacttcgcc atggtcaacg cgatgatggg catcggcgga ctgctcggcg gcctcctggc
    17641 gggcatgacg gactcgctcg ccgtcttcca ggcactcttc ctgctcgacg cggcgtcctt
    17701 cctcgtcacc ggctggctgg tcgcccggga ggtccgccgg cgccggtcgg tggagccgcc
    17761 caccggggag accccgccgg aggccgcggc ggccgaccag ccccgcagca gctaccgtgc
    17821 ggtgctgggg caccgctggc tggtcgccct gctggtcgtg gtgctggtcc tgttcaccgt
    17881 cggctactcc cagctcaact ccggcatgcc cgccgccctc ttggccgaca gccgcctcgg
    17941 ccccaccgag ctcggtgtgc tcttcgccgc caacaccgcg gccgtcgtcc tggtccaggc
    18001 ggcactgatc ggccggatca agcaggtcac cgcgggtgtg gccctcgcgc tgctcgccgc
    18061 cagctgggcc gccttctggc tgctgatctg ggcggtcacc ggcctcagcg gcggcctggt
    18121 cgccctgctc gtcggcgtca tcgccatggt cgtcttcgcg gtgggggagt ccctgctggc
    18181 cgcgaccggg cccaccctgg tcaacagctg ggccgacgac tccaaccggg ggcgcttcaa
    18241 cgccgcctac ggcttcgtct gttcactcgg cttcacggtc ggcccgctcg tctcggggcg
    18301 cctgaccgac gacggccaca ccacgtcgat gatgctcggc ttcacggccg tcctcgcggt
    18361 cctggcgctg atcacggtcc gttcccggtt cctgccgagg acacccctgt ccggcctgga
    18421 gaggaccggc cacgaggacg ccgcagagga agacgcccgg gcctgacggc tgtcgcaggc
    18481 cccgtaccac ccgcacccac ccgaaggaga cccctgccat gtccacccgt gttctcgtct
    18541 gccgctggga cccctacatc ctcgaagcgc tgcgcgcgga gggagccgag gtcgccctcc
    18601 tcttcgacac cttcgaggcc gcccacttcc acgtcgacga ggaggtgctg aagaccctgc
    18661 catacgtctt ccgcatcaac agcttcgacg acatggacga actcggccag gtcgccaccc
    18721 agctcaagaa cgacggctgg ctccccgacc gggtggtgag cctctcggag ttcagccagt
    18781 acggcgccgg ctacctcgcc cagctcctcg gctgcgccca gcccaccctg gagatggccc
    18841 tcaacacccg cgacaagcgg gccatgaagc aggcggtgcg cgccgccggg gtcacctgca
    18901 cggacttcgt gtcgctgcgc acctccgagg tggccgcgag cgtgcgccgc accgccgagg
    18961 agatcggctt ccccgcggtg gtcaagccct gcgcgggcct gggcaccctg ggcacgagct
    19021 gggtgcactc agaggaggag ctgaccaagc tcctcaccga cctcggagcc gacaacaccg
    19081 agcacttcct gatggccgaa cggcccgtgt ccggcgacga gttccacgtc gacgcgatct
    19141 gggtggacgg ccgcagcaag gtcctgggca tcatgcgcta cctgcggccg cggctggcca
    19201 tcgagacggc cggcgagagc aacggctccg tgctgctgcc gcgcgaggag tgggccgaac
    19261 tgtacgcgga cgtcgaggag gcccaccgcc gcgtcaacga cgccctcggc atccgcgagg
    19321 gcatcaccca cctggagttc ttcaagcagc cgggggagcg cgaggtggtg ttctccgaga
    19381 tcgcctcccg gttcgcgggc ggcggcatca ccgcgaccta ccgcgcgctc ggcgacgacc
    19441 tgcgcatcgc ctggatcaag tcggtggtcg accccggccg cccggcgccc tacgcggacg
    19501 gcgagcccag ccggtacgtg ggctggatca acctggcgcc gtccgaggcc ggccggatca
    19561 ccgccgagcc cacccaggcc gagatcgacg cgttcgacta cgtcctggag acggtgcgcc
    19621 cgcacggcgt gggcgacgac ttctccgacc cccacccctc cgcgtggtgc ctgcacctca
    19681 tctacggggc cgactccctg gagcagttcg aggagcgtgg ccgggagctg gagaaggccc
    19741 tcaacagcag cttccgcacc gaaccgaccg acgcctgacc acccctccaa cccgcgcacc
    19801 gcttaccact cagccttcac cactcaccgc tttccgaacc gcagacgagg aagagacgaa
    19861 catgactgag cccacgtacg agaaggaagt ccgcggctac ttcgccgaca aggccgaggc
    19921 ctacgacgac gtcgacctcc agccctactg ggtcctctcc gaccgcctgc tcgccgacgc
    19981 cctccgcgag gacgtcatca gcgccctgcc ggaggacttc gccttcctcg acgccggcgg
    20041 cggcaccggc cgctggacct ccttcttcgc ccaggaggcc ccccggagca cgggcgtcct
    20101 cttcgacctc acccgggaaa tgatcaaggt cgcggaggcg aaggccgccg aacgcggctt
    20161 cgccgaccgc gtccgcttcg tccagggcga cctggccgac gtgggggaga cgctgcgcgg
    20221 ggagtccttc gacctggcgt tcaacttcca caacgtcctc ggcttcgtgg cggaccccga
    20281 gcagaccatc aaggacgtcg caggactgct caagcccggc ggcctgctgg tgtcgttcct
    20341 gcccagcgtc tggcacaccg cgtggttcaa catcgccgtc ggcaacatcg acgaggccga
    20401 gaaggcgctg acccgccggg gccggttcac cgacaccatg cccgacatgc acctgtacga
    20461 cgtgcagcgc atcgaggaga tgcacgccgc ggccggactg gagatcgacg cgctctccgg
    20521 cttccccaac ctcatctacc ccggctacca ggagacccag ctccacggct ccaccgaaca
    20581 gctcgtggac atcctggccg gcgacgactt cgagcgcgtc ctcgccatgg agaagcgggt
    20641 ccgcaaggcg cccggcatcg cgggacgcgg caacaacctc ttcgtcgtcg cccgccgccc
    20701 cgcctgaccg cgacagggag cacaccacca tggccgtcga cctgctgtcg gagtccttcg
    20761 cccgggaccc gcacccgcac tacacccacc tgcgcacgac cgaccccgtg tggtgggacg
    20821 aggcgacaca gagctggtac gtcacc
//
