LOCUS       NZ_CP015588            21113 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces alfalfae strain ACCC40021 chromosome, complete genome.
ACCESSION   NZ_CP015588
VERSION     NZ_CP015588.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces alfalfae
  ORGANISM  Streptomyces alfalfae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8625867)
  AUTHORS   Gu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2016) Institute of Agricultural Resources and
            Regional Planning, Chinese Agricultural Academy of Sciences, 12
            Zhong Guan Cun South Street, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04; Celera Assembler v. 8.0;
            GapCloser v. 1.12
            Genome Coverage                   :: 310.8
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 02:19:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,535
            CDSs (total)                      :: 7,444
            Genes (coding)                    :: 7,210
            CDSs (with protein)               :: 7,210
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 107 of 234
            Pseudo Genes (incomplete)         :: 177 of 234
            Pseudo Genes (internal stop)      :: 26 of 234
            Pseudo Genes (multiple problems)  :: 73 of 234
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:53:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3127910
            Orig. end                         :: 3149023
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015588.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21113
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11113](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11113)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            308..2443
                     /locus_tag="A7J05_RS13000"
                     /old_locus_tag="A7J05_12530"
     CDS             308..2443
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644057.1"
                     /locus_tag="A7J05_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12530"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_076684609.1"
                     /transl_table=11
                     /translation="MRRANPRTIVVWSLVALVGATGWSVLALARDEEVSAAWMVAAALG
                     SYAIAYRFYARFVAYRVLKVDRTRATPAERLDNGIDFHPTDRRVLLGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGTIWIIAGVIFAGAVQDMVVLFFSTRRDGKSLGQMAREEIGPFGGA
                     AALLAAFAIMIILLGVLALVIVNALAESPWGTFSIAMTVPIALLMGFYLRVLRPGRVTE
                     VSLIGIALLLLALVAGRWVAESSLADTFTLAPSTLVIWLVAYGFIASILPVWMLLAPRD
                     YLSTFMKIGTILLLALGVVLTLPTLKMDPVTDFASRGDGPVFAGSLFPFVFITIACGAL
                     SGFHALISSGTTPKMIQKETQVRMVGYGSMLMESAVAIMALVAASIIDPGLFFAMNAPA
                     GVVGDTVQEASKAVANFGYSISPADLARAAEQVEEESLLSRTGGAPTLAIGVSEIFSKV
                     TGDSMRAFWYHFAIMFEALFILTALDAGTRVGRFMLQDMLGNVHKPFRNVSWKPGLILT
                     SAAVTGLWGYFLWVGVHEPLGGINQLFPIFGIANQLLAAVALAVCTTLLVKSGRLKWAW
                     ITAVPLAWDATVTLTASWQKVFSSDPRVGFFQQRSDYQDAIEAGMVLPPAKTMDDMHTV
                     VTNSTVDGVISAVLALLIVVVILDAGRVCLRHIRDPHASRLSEAPYVESRLTAPDGLFA
                     TREEKQRASEQEPAARP"
     gene            2440..2640
                     /locus_tag="A7J05_RS13005"
                     /old_locus_tag="A7J05_12535"
     CDS             2440..2640
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644058.1"
                     /locus_tag="A7J05_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12535"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_062782253.1"
                     /transl_table=11
                     /translation="MTAPLLRALRRLRWYVREFTDESAYERYVAHLRKEHPHTAVPDRR
                     AFERMRTERRESDPRQGFRCC"
     gene            2760..3029
                     /locus_tag="A7J05_RS13010"
                     /old_locus_tag="A7J05_12540"
     CDS             2760..3029
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983585.1"
                     /locus_tag="A7J05_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12540"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_076684611.1"
                     /transl_table=11
                     /translation="MSDAPEVNRPVVTPVRVVIAVCLVAPFVAMLWVGSYAKVDPAFIG
                     IPFFYWYQMLWVVISTALTMVAYQLWQRDQRARKAEQVRGGAGR"
     gene            3026..4669
                     /locus_tag="A7J05_RS13015"
                     /old_locus_tag="A7J05_12545"
     CDS             3026..4669
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="A7J05_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12545"
                     /product="sodium:solute symporter"
                     /protein_id="WP_076684613.1"
                     /transl_table=11
                     /translation="MNVLAAGTGGVNGIALAVFIFFFVAVTVMGFLAARWRKAETESLD
                     EWGLGGRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTF
                     LPRLWSVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVM
                     GVGGGPDTNWFIKDLPLLIAFAVLAAYTYSSGLRAPALIAFVKDGLIYLVIAVAIIYIP
                     IKLGGFDEIFQAADAKFSAANDAAGKPVAGLAPGEAGQWTYATLALGSALALFMYPHSI
                     TATLSSKSRDVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVENGQLAIPQLFENMFP
                     DWFTGVAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFLKPDATAEQETKVSKLVSLLV
                     KVGALAFVLTMDKTVAINFQLLGGIWILQTMPALVGGLFTRWFHRWALLAGWAVGMAYG
                     TLAAYGVASPTQKHFGGSSDEIPGIGEIGYIGLTAFVLNVIVTVVLTFVLRAAKAPDGI
                     DETSPEDYTADAGDPGVIEELPPATAGAAH"
     misc_feature    4786..4800
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.51"
                     /tool="antismash"
     regulatory      4815..4951
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    4817..4831
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     gene            5079..7538
                     /locus_tag="A7J05_RS13020"
                     /old_locus_tag="A7J05_12550"
     CDS             5079..7538
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444560.1"
                     /locus_tag="A7J05_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12550"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_076684616.1"
                     /transl_table=11
                     /translation="MTIAPADPVSATKPPNAEGAEGTDGPGAALLRTLTDLTADLPDAD
                     PGRVAAAALRGRSARGAAEIATELRELATEAAAGLISDDPEYSKLAARLLSIGIREEAA
                     TQGVRSFTESIAVGHREGLIADRTAAFVTEHGARLDALVEAALADGADFRFGYFGLRTL
                     HSRYLLRHPITRQVIETPQHFMLRVASGLAEDEGARAVDEVAALYGLMSRLDYLPSSPT
                     LFNSGTRHPQMSSCYLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRVRARGSLIR
                     GTNGHSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDAR
                     RTHNLNLAHWIPDEFMRRVAADQDWSLFSPADVPDLVDLWGEEFDAAYRGAEAAGLAKK
                     TLPARELYGRMMRTLAQTGNGWMTFKDAANRTANQTAEPGHTVHSSNLCTEILEVTDDG
                     ETAVCNLGSVNLGAFVDPAVGDIDWERLDATVRTAVTFLDRVVDINFYPTEQAGRSNAK
                     WRPVGLGAMGLQDVFFQLKLPFDAPEARALSTRIAERIMLAAYEASADLAERPQAPSAG
                     SGAGGTPVGPLPAWEKTRTARGVLHPDHYDVEPAWPERWDALRARIARTGMRNSLLLAI
                     APTATIASIAGVYECIEPQVSNLFKRETLSGEFLQVNAYLVQELKRLGVWDARTREALR
                     EAGGSVQGFGWLPEDVRALYRTAWEIPQRGLIDMAAARTPFLDQAQSLNLFLETPTIGK
                     LSSMYAYAWQQGLKTTYYLRSRPATRIARAAGGPSAAGATPVPRQAADPDAVACSLENP
                     ESCEACQ"
     gene            7538..8560
                     /locus_tag="A7J05_RS13025"
                     /old_locus_tag="A7J05_12555"
     CDS             7538..8560
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966409.1"
                     /locus_tag="A7J05_RS13025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12555"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_062782267.1"
                     /transl_table=11
                     /translation="MSNTTSSEKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEV
                     DLHSDVADLAKLSPGEQHMIGRLVAFFATGDSIVSNNLVLTLYKHINSPEARLYLSRQL
                     FEEAVHVQFYLTLLDTYLPDPDDRAAAFDAVEEIPSIREKAEFCFRWMDSVEKLDRLET
                     RADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSF
                     AFDVVDTVRKEEPELFDDALRTQVTDMLKEAVEAELQFARDLCGDGLPGMNTDSMREYL
                     QCVADQRLERLGFAPVYGSSNPFSFMELQGVQELTNFFERRPSAYQVAVEGSVSFDDEF
                     "
     gene            complement(8628..10004)
                     /locus_tag="A7J05_RS13030"
                     /old_locus_tag="A7J05_12560"
     CDS             complement(8628..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950763.1"
                     /locus_tag="A7J05_RS13030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12560"
                     /product="cytochrome P450"
                     /protein_id="WP_076684618.1"
                     /sec_met_domain="p450 (E-value: 1.6e-69, bitscore: 233.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDSAVPVPTAPGSGPLRTPPLVKGGAPLLGHAWNLVRDPLGFL
                     SALRDHGDLVRIRLGPKTAYVVCDPRLVGAMLKSPEYIVGGPLWDTLEVLLGKGVATSN
                     GRLHRRQRRMMQPAFRPERIADYAKVMEEEARATAARWQPGSTVDVGAEMFRTAVRIVS
                     RSLLEVESIGAKADRIADSLHTVFDGLYRRMVLSVGPLHRVPTPANRRFESALADLHAL
                     VDEIIAERRDAGPGGPDDLLAELLRATDEAGDPLTHQEIHDHVVSLVVAGAENVASTLA
                     WTFHLLTEHRDYERQLIDEVNFVAPDRAITFADLGELRHTRNVVTEAMRIRPAAWIFTR
                     RSTAETELGGYRIPADADIVYSVYAMQRDPRSFERHLEFDPGRWNPERAAEVPEFAMMP
                     FSVGNRKCPGDHFSLAELALILGTVAPKWRLEPVEETDTDTRVGITLHPKKLLMRVEPR
                     "
     gene            complement(10001..11113)
                     /gene="cyc1"
                     /locus_tag="A7J05_RS13035"
                     /old_locus_tag="A7J05_12565"
     CDS             complement(10001..11113)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384601.1"
                     /locus_tag="A7J05_RS13035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12565"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_335755776.1"
                     /sec_met_domain="T1TS (E-value: 2.6e-63, bitscore: 213.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAYSRSTSQTQPRTQTAMVPPALAVPVIERQFPRSLHPYWPKLQ
                     EKSRTWLREMRLMPPDKVERYADSLCYTDLVAGYYIGAPDELLTAIADLSSWFFAWDDR
                     HDRDSVHGRAGQWRRLCRGLHDTLDDPQRHLTHADPLVAGFADCVLRLYSFLGPSWNAR
                     FARHFHPVIDAYDQEFRNRRSRTVPPVDTYIELRRLTFAHWAWIDLLEPTARRELPRHI
                     RKHPAYRRAALATQDFSAWYNDLCSLPKELAGDELHNLGISLIHHEGLTLEEAVREVHR
                     RVVGCVTEFLRAEEEVLVLAGKLADGTRNGEELADALKSCVFNMRNWFSSVYWFHHESG
                     RYRVDSWDDRSMPPYVSEEIMAENELVGEE"
     gene            complement(11414..12064)
                     /gene="def"
                     /locus_tag="A7J05_RS13040"
                     /old_locus_tag="A7J05_12570"
     CDS             complement(11414..12064)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="A7J05_RS13040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12570"
                     /product="peptide deformylase"
                     /protein_id="WP_076684620.1"
                     /transl_table=11
                     /translation="MAQDTDQQASGGVLPVDGEGFVIDTEDCEARETAYRERGTSRPIT
                     VVGNPVLHKECKEVTAFDDDLAKLVDDMFASQRTAQGVGLAANQIGVDLKVFVYDCMDD
                     EGVRHVGVVCNPVLRELPADRRRLDDSGEGCLSVPTAYAPLARPDYAEVSGQDEKGNPI
                     KVRGGGYFARCLQHETDHLYGYLYIDRLSKRERRDALRQMEEGTPRYPVVPND"
     gene            complement(12146..13126)
                     /locus_tag="A7J05_RS13045"
                     /old_locus_tag="A7J05_12575"
     CDS             complement(12146..13126)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="A7J05_RS13045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12575"
                     /product="hypothetical protein"
                     /protein_id="WP_062782280.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRSAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGGVTASGEPTGMDLGSAAVRLSPEGEAEVVWGRRLDPARIELLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTGDGHSYPVFDEIELWAPSPVPTWVVLLEAATEEDRD
                     ALERLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     SPGAVWVPERECGIAAPAALVRGLLDSWVADSPDSRDWRDLEEVC"
     gene            complement(13304..14554)
                     /locus_tag="A7J05_RS13050"
                     /old_locus_tag="A7J05_12580"
     CDS             complement(13304..14554)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644068.1"
                     /locus_tag="A7J05_RS13050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12580"
                     /product="HD domain-containing protein"
                     /protein_id="WP_076688902.1"
                     /transl_table=11
                     /translation="MPAALAQAVAALLALTALAWTLWHGITEGRTALAFGVLIGLGELA
                     RWGSARTREPAPLGAAGALAYALLGENAGHHTHHGAPQVIAVVVAASLVAAVPHVARGK
                     GPSPDQVARRLLSVGFAAVCFQPLYNSGLLAERVGHGPYFALVIVAVLVLTALCDAVLA
                     AAMAHARTRWPFGPLLRDELRALLGIGSAVCATGAVMALAVAVAGLWALPVFSLPLLLT
                     QLSFRRYAAVRATYRQTIASLARATEIAGCTPQGHAHRVARLSKAVGRDLGLFEPDLTV
                     LEHAALMHDIGQLSLVDPVPEGATAGLPEAEQRRIALLGGAVVRQTGVDPAVAVVVERQ
                     ADPYREQPLAARIVRTANAYDEMARGEGPSGALGGPLHALERLRLATGRDHQPEVVESL
                     ARVLARERSGPRGVGRG"
     gene            complement(14644..16032)
                     /locus_tag="A7J05_RS13055"
                     /old_locus_tag="A7J05_12585"
     CDS             complement(14644..16032)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376704.1"
                     /locus_tag="A7J05_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12585"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_076684622.1"
                     /transl_table=11
                     /translation="MRSVPMWARAYILCVTLAGASCAVSALGPHTPWPAVALLAVLYAG
                     CEHEALLDRLAGRTGAAARRRAPRGPGTLFPVLLAGVFLLPPAAAALVAVPGALLARAD
                     RRPRWVRRVWRAAQLALASWTSARLYAALGGPAATAAPDFPYVLGPAGAAVLAFACVLT
                     VLDGGILATAERVPARTAWRGLFARSLAPVAVHGLAGLMMAVLWTSPYGPPAALLVLLP
                     MGVSCWAFAQYHHERAAHQATIRALVQAVDLKDRYTRGHSERVGRASVLIAEELGMDDD
                     RVEVLRFAGILHDVGKLGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIGFLGEAR
                     EAILHHHERIDGTGYPYGLAGRQIPESARVVAVADAFDAMTSTRSYSRARPVAVALEEL
                     DRCAGAHFDPVMVAALTRALDRHGWHPGVTSDLPGRVPDQLGDQRGNVPPELPAPSASG
                     PAAR"
     gene            complement(16229..16537)
                     /gene="rsrA"
                     /locus_tag="A7J05_RS13060"
                     /old_locus_tag="A7J05_12590"
     CDS             complement(16229..16537)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480448.1"
                     /locus_tag="A7J05_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12590"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_076684623.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDCTKFETHFEECSPCL
                     EKYGLEQAVKKLVKRCCGSDDVPVDLRAKVMGRIDLIRSGQTVPDQDVIQDVTASEA"
     gene            complement(16534..17217)
                     /locus_tag="A7J05_RS13065"
                     /old_locus_tag="A7J05_12595"
     CDS             complement(16534..17217)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="A7J05_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12595"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_205576593.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPRENPERSETAAERTARFERDALTFLD
                     QMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKK
                     QREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKKALQAIPEEFRIAV
                     YLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGKSNGT
                     KGSGS"
     gene            complement(17450..18124)
                     /locus_tag="A7J05_RS13070"
                     /old_locus_tag="A7J05_12600"
     CDS             complement(17450..18124)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190545.1"
                     /locus_tag="A7J05_RS13070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12600"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_076684627.1"
                     /transl_table=11
                     /translation="MTHETRSGPGESTGPVETIETDTGTARITWRTAREPRLLLAVSHG
                     AGGGIEARDLKALAAELPAHGVTVALVEQPWRVAGKKLAPAPRTLDAGWRGIWPALAER
                     GLPVISGGRSAGARVACRTAAELGAAAVLALSFPLHPPGKPEKSRADELLGAGVPVLVV
                     QGGNDPFGRPAEFPAGDGYELAEVPYADHGFAVPKRAEIGQDEAVKRVTDAVVRWTGML
                     DA"
     gene            complement(18126..18941)
                     /locus_tag="A7J05_RS13075"
                     /old_locus_tag="A7J05_12605"
     CDS             complement(18126..18941)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="A7J05_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12605"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_062782296.1"
                     /transl_table=11
                     /translation="MCGRYASSRGPEDLAGIFEIEKYEPEEALAPDYNVAPTKEVYAVL
                     DRPLKDADDPAPVRQLRTLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFASRR
                     CVIPADGYYEWVTAPEERQLEVEGKKKRPRKQPYFVTPADGSVFAMAGLFEFWRDKTLP
                     DEHPLAWWVTCTVITTEAETAPLAVAPAQGPRSLADIHPRMPLMLTPDRWDAWLDPSRT
                     DVEDLRPLLEPPPHGLMRAFPVSTAVSNVRNNGPELLKELDGPEEGTLF"
     gene            19040..19774
                     /locus_tag="A7J05_RS13080"
                     /old_locus_tag="A7J05_12610"
     CDS             19040..19774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480455.1"
                     /locus_tag="A7J05_RS13080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_12610"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_076684630.1"
                     /transl_table=11
                     /translation="MDQGLETAADASLTDLWDRILGTQAAPETWLVIATGVVALAVVVP
                     HGVWRLARNAITIAHEGGHGLVALLTGRRLDGIRLHSDTSGLTVSRGRPSGIGMILTAA
                     AGYTAPPLLGLGGAALLGSRRITALLWIATALLVAMLVMIRNAYGVLTVVLTGGAFLLV
                     SWLAGSEVQAAFAYAVVWFLLLGGVRPAFELQSKRRRGGAGDSDADQLSRLTHVPAGLW
                     LFFFHAVSLCSLMGGARWLLAV"
ORIGIN
        1 catcgagacc tcgctcgcca ccccgcgcga ggcgggcctg ctcggcacgg acgtcggcct
       61 gcccatgctg ctgctctccc ggcactccct ggacggcgac ggccggcccg tggagtgggt
      121 gcgctcggtc taccgcggcg accgctacaa gttcgtggcc cgcctgaagc ggccgaccga
      181 ctgagaccgc cgtcccggcc cgccctgacc ctccctcccc tgacgcgact ccgtacgcgg
      241 tctggcgcac ggcactccgc tgccctacct tcctgacgtc atcgcttgat gaacgggagg
      301 cggcccggtg cgcagagcga acccccgaac catcgtcgtc tggagcctcg tcgcgctggt
      361 cggcgccacg ggctggagcg tcctcgcgct ggcacgcgac gaggaggtgt cggccgcgtg
      421 gatggtggcg gcggccctcg gctcgtacgc catcgcctac cgcttctacg cgagattcgt
      481 cgcgtaccgg gtgctgaagg tcgacaggac gcgggcgacg cccgccgagc ggctcgacaa
      541 cggcatcgac ttccacccga ccgaccgccg cgtgctgctc ggccaccact tcgcggcgat
      601 cgcgggcgcg ggaccgctgg tggggccggt gctcgccgcg cagatggggt atctgccggg
      661 caccatctgg atcatcgccg gcgtgatctt cgccggggcc gtgcaggaca tggtcgtgct
      721 gttcttctcc acccggcggg acggcaagtc gctggggcag atggcgcgcg aggagatcgg
      781 gccgttcggc ggggccgccg cgctgctcgc cgccttcgcc atcatgatca ttctgctcgg
      841 cgtgctcgcc ctggtgatcg tcaacgcgct cgccgagtcc ccgtggggca ccttctccat
      901 cgcgatgacc gtgcccatcg ccctgctcat gggcttctac ctgcgggtcc tgcggccggg
      961 gcgggtcacc gaggtctccc tcatcggcat cgcgctgctg ctgctcgcgc tggtcgcggg
     1021 gcgctgggtc gcggagtcct cgctcgccga caccttcacg ctcgcgccct cgacgctggt
     1081 gatctggctg gtcgcgtacg ggttcatcgc ctcgatcctg ccggtgtgga tgctgctcgc
     1141 gccgcgcgac tacctctcga cgttcatgaa gatcggcacc atcctgctgc tcgccctcgg
     1201 ggtggtgctc accctgccga cgctgaagat ggaccccgtg accgacttcg cctcccgcgg
     1261 cgacggaccg gtcttcgcgg gctcgctgtt ccccttcgtc ttcatcacca tcgcgtgcgg
     1321 ggccctctcc ggcttccacg cgctgatctc ctcgggcacg acaccgaaga tgatccagaa
     1381 ggagacgcag gtcaggatgg tcggctacgg ctccatgctg atggagtcgg ccgtcgcgat
     1441 catggcgctc gtcgccgcgt cgatcatcga tcccggcctt ttcttcgcga tgaacgcgcc
     1501 cgcgggcgtc gtcggcgaca ccgtgcagga ggcgtcgaag gccgtcgcga acttcgggta
     1561 ctccatctcc cccgccgacc tcgcgcgcgc cgccgagcag gtggaggagg agtcgctgct
     1621 ctcgcgcacc ggcggcgcgc ccacgctcgc gatcggcgtc tccgagatct tctcgaaggt
     1681 cacgggcgac tcgatgcggg ccttctggta tcacttcgcg atcatgttcg aggcgctctt
     1741 catcctcacc gcgctcgacg cgggcacgcg cgtggggcgc ttcatgctcc aggacatgct
     1801 cggcaacgtc cacaagccct tcaggaacgt gagctggaag ccgggactca tcctgaccag
     1861 cgcggccgtc accggtctgt ggggctactt cctctgggtc ggcgtgcacg aaccgctcgg
     1921 cgggatcaac cagctcttcc cgatcttcgg catcgccaac cagctcctcg cggccgtcgc
     1981 cctcgccgtc tgcaccacgc tgctcgtgaa gtccgggcgc ctgaagtggg cctggatcac
     2041 cgcggtcccg ctcgcctggg acgccacggt gacgctcacc gcgagctggc agaaggtgtt
     2101 ctccagtgat ccccgcgtgg gcttcttcca gcagcgctcc gactaccagg acgccatcga
     2161 ggcgggcatg gtcctgccgc ccgccaagac catggacgac atgcacaccg tcgtcaccaa
     2221 ctccacggtg gacggcgtga tctcggcggt cctcgccctg ctcatcgtcg tcgtgatcct
     2281 ggacgcgggc cgcgtctgcc tgcggcacat ccgcgacccg cacgcctcac ggctgagcga
     2341 ggccccgtac gtggagtccc ggctgaccgc ccccgacggg ctcttcgcca cccgcgagga
     2401 gaagcagcgg gcctcggagc aggaaccggc ggcccgccca tgaccgcccc actgctgcgc
     2461 gccctgcgcc gactgcggtg gtacgtccgc gagttcaccg acgagtcggc ctacgagcgg
     2521 tacgtggcgc acctgcgcaa ggagcatccg cacaccgccg tgcccgaccg ccgggcgttc
     2581 gagcgcatgc ggacggagcg gcgggagtcg gacccgaggc agggcttccg ctgctgctga
     2641 gtagcgcggc gacacttcga gtcccgtccg ttatccggac aggggttcca tagcgcgaga
     2701 ctgtcgctta gatttcccgc acgttaagca tgggataagt gagggaacgg agccgcgata
     2761 tgtcagatgc gcctgaagtg aacagaccgg tggtcacgcc ggtccgcgtg gtcatcgccg
     2821 tctgcctcgt cgcgccgttc gtggcgatgc tctgggtggg ttcctacgcc aaggtggacc
     2881 cggccttcat cggcatcccg ttcttctact ggtaccagat gctgtgggtc gtcatctcca
     2941 cggcgctcac gatggtcgcc taccagctgt ggcagcgtga ccagcgcgcc cgcaaggccg
     3001 agcaggtccg gggaggtgcg ggccgatgaa cgtcctcgca gccggcaccg gcggtgtcaa
     3061 cggcatcgcg ctcgccgtct tcatcttctt cttcgtcgcg gtcacggtca tgggcttcct
     3121 cgcggcccgc tggcgcaagg ccgagaccga gagcctcgac gaatggggcc tgggcggccg
     3181 ctcgttcggc acctgggtca cctggttcct gctcggcggc gacctctaca ccgcgtacac
     3241 cttcgtcgcc gtccccgcgg cgatctacgc ggcgggcgcg gccgggttct tcgcggtgcc
     3301 gtacacgatc ctcgtctacc ccctcatctt caccttcctg ccgcgcctct ggtcggtctc
     3361 gcacaagcac gggtatgtga cgacctcgga cttcgtgcgc ggacgcttcg gctccaaggg
     3421 gctctccctg gcggtcgcgg tcaccggcat cctcgccacc atgccgtaca tcgccctcca
     3481 actcgtcggc atccaggcgg tgctcgacgt catgggcgtc ggcggcggcc ccgacaccaa
     3541 ctggttcatc aaggacctgc cgctcctgat cgccttcgcg gtgctcgcgg cgtacacgta
     3601 ctcctctggt ctgcgcgcgc ccgccctgat cgcgttcgtg aaggacggcc tgatctacct
     3661 ggtcatcgcc gtggcgatca tctacatccc gatcaagctg ggcggcttcg acgagatctt
     3721 ccaggccgcc gacgccaagt tctccgccgc caacgacgcc gcgggcaagc ccgtcgcggg
     3781 tctggctccg ggcgaggcgg ggcagtggac gtacgcgacg ctggccctcg gctccgcgct
     3841 cgcgctcttc atgtacccgc actcgatcac ggcgacgctc tcctccaaga gccgcgacgt
     3901 gatccgccgc aacaccacga tcctgccgct gtattcgctg atgctcggcc tgctcgcgct
     3961 gctcggcttc atggcgatcg cggccggggt caaggtggag aacgggcagc tcgcgatccc
     4021 tcagctgttc gagaacatgt tccccgactg gttcacgggc gtggccttcg ccgcgatcgg
     4081 catcggcgcg ctcgttcccg ccgccatcat gtccatcgcc gccgcgaacc tcttcacgcg
     4141 caacatctac aaggacttcc tcaagccgga cgcgacggcc gagcaggaga ccaaggtctc
     4201 caagctggtc tcgctcctgg tgaaggtcgg cgcgctggcc ttcgtcctca ccatggacaa
     4261 gaccgtcgcg atcaacttcc agctgctggg cggcatctgg atcctgcaga ccatgcccgc
     4321 gctggtcggc ggcctgttca cgcgctggtt ccaccgctgg gcgctgctgg cgggatgggc
     4381 ggtcggcatg gcctacggca ccctggccgc gtacggcgtc gcctcgccca cgcagaagca
     4441 cttcggcggc tcgtccgacg agatccccgg catcggcgag atcggctaca tcggcctcac
     4501 cgcgttcgtc ctgaacgtca tcgtgacggt ggtcctcacc ttcgtcctgc gggccgcgaa
     4561 ggctcccgac ggcatcgacg agacctcgcc cgaggactac accgcggacg cgggagaccc
     4621 cggcgtgatc gaggaactgc ccccggccac cgcgggcgcc gcgcactgac cgcgccaccc
     4681 tcacaggggc cgcacagggc ctcgtccact gccgcgcgaa gggccgccgg gcaaccggcg
     4741 gcccttcgcc gtacccgcgc ccgtccccgc acccctcccc cgtcgacaca agatgtgggt
     4801 ccgcttcccg gacccggcac aagatgtatg ctcgtgctcg ctgtcgccgc aggggaatcc
     4861 ggtgcaagtc cggaactgtc ccgcaacggt ggacgtgtac gcatttggcg tacgcggagt
     4921 ccgaagacct gccggcagcg cacccgtgcc gtccggcccg ggtgccgacc gtccgggcct
     4981 cgtggaatgg gccggtggac gcggtgcacc gccctgcgcg cgtgcccccg tgcgccctcc
     5041 cctcccgcgg cccggagccg agcgagggag agccccacgt gaccatcgcg cctgccgatc
     5101 cggtgtcagc gacgaagccg ccgaacgccg agggtgccga aggaaccgac ggcccgggag
     5161 ccgcactgct gcgcaccctg accgacctca ccgccgacct ccccgacgcc gaccccggcc
     5221 gggtcgccgc cgccgcgctg cggggccgct cagcccgcgg tgccgccgag atcgcgaccg
     5281 agctgcggga gctggcgacc gaggccgccg cggggctcat ctccgacgac ccggagtact
     5341 cgaagctggc ggccaggctg ctctcgatcg gcatccgcga ggaggcggcc acgcagggcg
     5401 tgcgctcctt caccgagtcc atcgcggtgg gccaccgcga gggcctgatc gccgatcgca
     5461 cggccgcgtt cgtgacggag cacggggccc ggctcgacgc gctggtggag gcggctctcg
     5521 cggacggcgc cgacttccgc ttcggctact tcggcctgcg caccctgcac agccgctatc
     5581 tgctgcgcca cccgatcacc cgccaggtca tcgagacccc gcagcacttc atgctgcggg
     5641 tggcgagcgg cctggccgag gacgagggcg cccgcgcggt ggacgaggtc gccgcgctgt
     5701 acggcctgat gagccgcctg gactacctgc cgtcgtcgcc gacgctcttc aactccggca
     5761 cccggcaccc gcagatgtcg tcctgctacc tcctcgactc gcccctggac gagctggact
     5821 cgatctacga ccgctaccac caggtcgcgc gcctctccaa gcacgcgggc ggcatcgggc
     5881 tctcgtattc gcgcgtgcgt gcccgcggtt cgctgatccg gggcacgaac gggcactcca
     5941 acggcatcgt gccgttcctg aagacgctcg acgcctcggt cgccgccgtc aaccagggcg
     6001 gccggcgcaa gggcgccgcc gcggtctacc tggagacctg gcactccgac atcgaggagt
     6061 tcctggagct gcgggacaac accggtgagg acgcgcgccg cacgcacaac ctcaacctcg
     6121 cgcactggat ccccgacgag ttcatgcgcc gggtcgccgc cgaccaggac tggtcgctgt
     6181 tctcccccgc cgacgtgccc gacctcgtcg acctgtgggg cgaggagttc gacgccgcct
     6241 accgcggggc ggaggccgcc gggctcgcga agaagaccct ccccgcccgt gagctgtacg
     6301 gccggatgat gcgcaccctc gcgcagaccg gaaacggctg gatgacgttc aaggacgccg
     6361 ccaaccgcac cgccaaccag acggcggagc ccggccacac cgtgcactcc tcgaacctct
     6421 gcacggagat cctggaggtg acggacgacg gggagacggc cgtctgcaac ctgggctcgg
     6481 tgaacctcgg cgcgttcgtg gacccggccg tcggtgacat cgactgggag cggctcgacg
     6541 cgaccgtccg cacggccgtc accttcctcg accgcgtcgt cgacatcaac ttctacccga
     6601 ccgagcaggc cggccgctcc aacgccaagt ggcgcccggt gggcctcggc gcgatgggcc
     6661 tccaagacgt cttcttccag ctgaagctgc ccttcgacgc ccccgaggcg cgggcccttt
     6721 ccacccgtat cgccgagcgg atcatgctcg ccgcgtacga ggcgtcggcg gacctcgccg
     6781 agcgccccca agcaccttcg gcaggctccg gtgcaggggg gaccccggtc ggcccgctgc
     6841 cggcctggga gaagacccgc accgcgcgcg gcgtcctgca ccccgaccac tacgacgtcg
     6901 agccggcctg gccggagcgg tgggacgcgc tgcgggcccg catcgcgagg accggcatgc
     6961 gcaactccct gctgctcgcc atcgcgccga cggcgaccat cgcctccatc gcgggcgtct
     7021 acgagtgcat cgagccgcag gtctccaacc tcttcaagcg cgagacgctc agcggtgagt
     7081 tcctccaggt caacgcctac ctggtccagg agctcaagcg gctcggcgtc tgggacgcgc
     7141 ggacccgcga ggcgctgcgc gaggccggcg gctcggtgca gggcttcggc tggctccccg
     7201 aggacgtccg cgcgctctac cgcacggcgt gggagatccc gcagcgcggc ctcatcgaca
     7261 tggccgcggc gcgcaccccg ttcctcgacc aggcgcagtc cctgaacctc ttcctggaga
     7321 cgccgaccat cggcaagctc tcctcgatgt acgcctacgc ctggcagcag ggcctgaaga
     7381 ccacgtacta cctgcgctcc cggcccgcca cgcgcatcgc ccgcgcggcc ggcggtccga
     7441 gcgccgccgg cgccaccccc gtcccccggc aggcggccga ccccgacgcc gtcgcctgct
     7501 ccctggaaaa tcccgagtcc tgcgaggcct gccagtgatg agcaacacga ccagctccga
     7561 gaagaacctg ctcgacccgg gcttcgagct gaccctgcgc cccatgcgct acccggactt
     7621 ctacgagcgc taccgggacg cgatcaagaa cacctggacc gtggaggagg tcgacctcca
     7681 ctccgacgtc gccgacctcg cgaagctctc gcccggcgag cagcacatga tcggccgcct
     7741 cgtcgcgttc ttcgcgaccg gtgactcgat cgtctccaac aacctggtgc tcacgctcta
     7801 caagcacatc aactcccccg aggcccggct ctacctgagc cgtcagctgt tcgaggaggc
     7861 cgtgcacgtc cagttctatc tgacgctgct cgacacctat ctgcccgacc cggacgaccg
     7921 ggctgcggcc ttcgacgcgg tggaggagat cccctccatc cgcgagaagg cggagttctg
     7981 cttccggtgg atggactcgg tggagaagct ggaccggctg gagacgcggg cggaccgccg
     8041 gcgcttcctg ctcaacctga tctgcttcgc cgcgtgcatc gagggcctgt tcttctacgg
     8101 ggccttcgcg tacgtgtact ggttccgcag ccgcggtctg ctgcacggcc tcgcgaccgg
     8161 cacgaactgg gtgttccgcg acgagacgat gcacatgagc ttcgcgttcg acgtggtgga
     8221 cacggtccgc aaggaggagc cggagctgtt cgacgacgcg ctccggacgc aggtcacgga
     8281 catgctgaag gaggccgtcg aggccgagct gcagttcgcg cgtgacctgt gcggcgacgg
     8341 tctgcctggc atgaacaccg actcgatgcg cgagtacctc cagtgcgtcg ccgaccagcg
     8401 tctggagcgg ctcggcttcg cacccgtcta cggttcgtcg aacccgttct ccttcatgga
     8461 gctccagggc gtgcaggagc tgaccaactt cttcgagcgg cggccctcgg cataccaggt
     8521 cgcggtggag ggttcggtct ccttcgacga cgagttctga ccccggcgcg gacccggtac
     8581 gggtgtgccc gccccctccc ctggcgggag cgggcacacc cgtcggttca gcggggctcc
     8641 acccgcatga ggagcttctt ggggtgcagg gtgatgccga cgcgggtgtc cgtgtcggtc
     8701 tcctcgaccg gctccaggcg ccacttcggt gccaccgtcc ccaggatgag ggccagttcg
     8761 gccaggctga agtggtctcc gggacactta cggttaccga cgctgaacgg catcatcgcg
     8821 aactccggca cttccgcggc gcgttccgga ttccagcggc ccgggtcgaa ctccaggtgc
     8881 cgctcgaagg aacgcgggtc gcgctgcatc gcgtacacgc tgtagacgat gtccgcgtcg
     8941 gccggaatgc ggtagccacc cagttcggtc tcggccgtgg acctgcgggt gaatatccag
     9001 gccgccggac ggatacgcat ggcctcggtc acgacattgc gggtgtgccg caactcgccg
     9061 agatcggcga aagtgatcgc gcggtccggg gccacgaaat ttacttcgtc aatcaactgc
     9121 ctttcatagt cgcggtgttc ggtcagcaga tggaacgtcc atgccagcgt cgaggcgaca
     9181 ttctccgctc ccgcgaccac cagggacacc acgtggtcat ggatctcctg atgggtgagg
     9241 ggatcacccg cctcgtccgt ggcgcgcagc aattccgcga gcaggtcgtc ggggcccccg
     9301 ggtccggcgt cgcggcgctc ggcgatgatc tcgtcgacga gggcgtgcag atcggcgaga
     9361 gcgctctcga agcgccggtt ggcgggggtc ggcacccggt gcagcggacc gaccgagagc
     9421 accatccggc ggtagagccc gtcgaagacg gtgtgcagcg agtcggcgat gcggtccgcc
     9481 ttggcgccga tcgactccac ctccaggagg gagcgcgaga cgatgcgcac ggccgtgcgg
     9541 aacatctccg cgcccacgtc gaccgtggaa cccggctgcc agcgggcggc cgtggcgcgg
     9601 gcctcctcct ccatcacctt ggcgtagtcg gcgatccgct cgggccggaa cgcgggctgc
     9661 atcatgcggc gctggcgccg gtgcagccgg ccgttgctgg tcgccacgcc cttgccgagg
     9721 agcacttcga gggtgtccca cagcggcccg ccgacgatgt actccgggct cttcagcatg
     9781 gccccgacga gccgcggatc gcagaccaca taggcggtct tcggccccag cctgatccgt
     9841 acgagatccc cgtgatcccg cagcgccgag aggaagccga gcgggtcgcg caccaggttc
     9901 caggcgtgac cgagcagggg cgcgccgccc ttcacgagcg gcggggtgcg cagcggcccg
     9961 gagcccggcg cggtggggac gggtaccgcg gaatcgacgc tcattcctca cctaccagtt
    10021 cgttttccgc catgatttct tcgctcacgt acgggggcat tgacctgtcg tcccagctgt
    10081 ccactcggta gcgcccggat tcgtggtgga accaatagac ggaggagaac cagttccgca
    10141 tattgaagac acaggacttc aatgcgtccg cgagttcttc gccatttcgt gtcccgtccg
    10201 ccagttttcc ggcgagtacg agcacttctt cctcggcccg gagaaattcc gtgacgcagc
    10261 cgacgacccg ccggtggacc tctcgtacgg cctcttcgag cgtcagcccc tcatggtgga
    10321 tgaggctgat cccgagattg tgcagttcgt ctcccgcgag ttctttgggg agcgagcaca
    10381 ggtcgttgta ccaggccgag aaatcctggg tcgcgagtgc cgcccgccgg tacgcgggat
    10441 gcttgcgtat gtggcgcggc agctcccggc gcgcggtcgg ctccaggaga tcgatccacg
    10501 cccagtgcgc gaacgtcagg cgccgcagct cgatgtaggt gtcgaccggg gggacggtgc
    10561 gggacctccg gttcctgaac tcctggtcgt aggcgtcgat caccgggtgg aagtggcggg
    10621 cgaacctggc gttccagctc gggcccagga aggagtacag gcgcaggacg cagtcggcga
    10681 accccgccac gagcgggtcc gcgtgcgtca ggtgccgctg ggggtcgtcg agggtgtcgt
    10741 gcaggccccg gcagaggcgc cgccactggc cggccctgcc gtgcaccgag tcccggtcgt
    10801 gccggtcgtc ccaggcgaag aaccagctgc tgaggtccgc tatcgcggtg agcagctcat
    10861 cgggcgcgcc gatgtagtaa ccggccacca gatcggtgta gcagaggctg tccgcgtacc
    10921 gctcgacctt gtccggcggc atcagacgca tttcgcgcaa ccaggtcctt gacttctcct
    10981 gaagttttgg ccaatacggg tgcagactcc ggggaaattg ccgctcgatc accgggaccg
    11041 ccagcgccgg aggaaccatt gccgtctgtg tgcgtggctg tgtctgtgaa gtgctcctgg
    11101 aatatgcagg cacgaacaaa cccctttcag ccgcctgagc gcgcgcccct ctcgccgtac
    11161 cgggcgcacg ccgtcgtgta tccccgcgct ttccattcag cactacaact gaccgttcag
    11221 ggaacagttt tgcgccattc actcccacgg ggcgccgaga acatcccctt acgtgaccga
    11281 atatggatct tcggcagccc gatccgctcg tacgcatgcg cgacgcacgc caacggcccc
    11341 tggtcggggg gtggttcccg tccaggggcc gctcgtgtca cgcggtgccc acgccgctca
    11401 ggcggcgcgc gcgtcagtcg ttcggcacca cggggtagcg cggggtgccc tcttccatct
    11461 gccggagcgc gtccctgcgc tcgcgcttgg agaggcggtc gatgtacagg tagccgtaca
    11521 ggtggtccgt ctcgtgctgg aggcagcgcg cgaagtagcc gccgccgcgg accttgatcg
    11581 ggttgccctt ctcgtcctgg ccgctcacct cggcgtagtc cgggcgggcc agcggggcgt
    11641 aggcggtcgg cacggagagg cagccctcgc ccgagtcgtc gaggcggcgc cggtcggcgg
    11701 gcagctcgcg caggaccggg ttgcagacca cgccgacgtg gcgcacgccc tcgtcgtcca
    11761 tgcagtcgta cacgaagacc ttcaggtcga cgccgatctg gttggcggcg aggccgacgc
    11821 cctgcgcggt gcgctggctg gcgaacatgt cgtcgaccag cttcgcgagg tcgtcgtcga
    11881 aggccgtgac ctccttgcac tccttgtgca ggaccggatt gccgacgacc gtgatgggcc
    11941 gggacgtgcc gcgctcgcgg taggccgtct cccgcgcctc gcagtcctcc gtgtcgatga
    12001 cgaagccctc gccgtcgacg gggagcaccc cgccggaggc ctgctgatca gtgtcctgcg
    12061 ccatgtccgc cgtacgcctt ccttggaacc ctcaagagtt tgtgccggta cagcctacgg
    12121 cgaacgtcgg gcggtgctcc ccgggtcagc agacctcctc gagatcccgc cagtcgcggg
    12181 agtccgggct gtcggccacc cagctgtcca ggagcccgcg caccagggcg gcgggcgcgg
    12241 cgatgccgca ctcccgctcc ggcacccaga cagcgccggg gctgcggtgg ccgagcggac
    12301 ccgggtggcc gggctcactg tggtcgtgcg ggtccaggtg ctccccgtcg ccctcgtcgc
    12361 tcggcatccg ggactcggag cacatgcggc acagcagccg caccgacgac gaccagtcct
    12421 cggcggcgaa gcccgcgtcg gcggcgagcc gctccagggc gtccctgtcc tcctcggtgg
    12481 cggcctccag gagcaccacc cacgtcggca cgggagaggg ggcccagagc tcgatctcgt
    12541 cgaacacggg gtacgagtgc ccgtcccccg tcgtgcgctc gccgtgcggg acgccgtcgt
    12601 gcagcacgac ctcgccccag cggcgcccgg aggagggcag cgggatggac agcagctcga
    12661 tgcgggccgg gtcgagcctg cggccccaca cgacctccgc ctcgccctcc ggggagagcc
    12721 gcacggccgc gctgcccaga tccatgcccg tgggctcacc ggaggcggtc accccgcccg
    12781 gcacccgcag tccgtacgcc tgccaggcgc ggcgggccag cggccagtcc tgcagggccg
    12841 tcgccgcgat gcccacgttc caccagtcag gggcaccggc cgagcggtcg aggagcgcga
    12901 cggcgcgcag cccggcggcg cgcgcctgct cccagtcgtg ccggaacttg tgcaggagcg
    12961 cgaggttgaa ccaggactcg gacagccagg gctccaggtc cgccgcgcgc gtgagcagcg
    13021 ctcccgcgtc ctcgtaccgg ccgtcgccga tcagcgtgaa cgcgcggtcg gtcgcctgcc
    13081 gccatgaggc ggagggccgg tgccgtccct tgccgaagat cctcacgatt cccgcctgat
    13141 tcccgcctgt cacgatttcg gaaagtcccg tcccgcgagg gcgcggcgtc gggccgatgc
    13201 ccccgtgcac cctcttcttc gcatccaacc acgtacggtc ggacggccgc tcattaccca
    13261 tgggttaccc agccggggac gagctaaggc ccgaccgtcg gcctcacccg cgccccacac
    13321 cccgcggacc gctcctctcc cgcgcgagga ccctcgccag ggactccacg acctcgggct
    13381 gatggtcgcg gccggtggcc agccgcagcc gctccagggc gtgcagcggg ccgcccagtg
    13441 cccccgaggg tccttctccc cgcgccatct cgtcgtatgc gttcgcggtg cgcacgatgc
    13501 gcgcggccag gggctgctcg cggtacgggt cggcctgccg ctccacgacc acggcgaccg
    13561 ccgggtccac cccggtctgc cgcacgacgg cgccgccgag cagtgctatg cggcgctgct
    13621 ccgcctcggg cagacccgcg gtcgccccct ccggcaccgg atcgacgagg gacagctggc
    13681 cgatgtcgtg catcagcgcc gcgtgctcca ggacggtcag gtccggctcg aagagcccga
    13741 ggtcgcgccc gaccgccttg ctgagccgcg cgacgcggtg ggcgtggccc tgcggggtgc
    13801 atccggcgat ctccgtggcc ctggccagcg acgcgatggt ctggcggtag gtggcccgca
    13861 ccgccgcgta gcgccggaag gagagctggg tgagcagcag cgggaggctg aacacgggca
    13921 gcgcccagag cccggccacg gccaccgcga gcgccatgac ggcccccgtc gcgcagacgg
    13981 cggagccgat gccgagcagg gcccgcagct cgtcgcggag cagcgggccg aagggccagc
    14041 gggtgcgggc gtgcgccatc gcggcggcga ggacggcgtc gcagagcgcg gtgaggacga
    14101 gcacggcgac gatgacgagc gcgaagtacg ggccgtggcc gacccgctcc gccaacaggc
    14161 cgctgttgta gaggggttgg aagcagacgg cggcgaagcc gacgctcagc agccgccgtg
    14221 ccacctggtc cggtgagggg cccttgccgc gcgccacgtg cggcacggcc gccaccaggg
    14281 aggccgcgac caccacggcg atcacctgcg gcgccccatg gtgcgtgtgg tgcccggcgt
    14341 tctcccccag cagcgcgtac gccagcgcgc ccgcggcccc gagcggcgcg ggctcccggg
    14401 tccgcgcgct cccccacctg gccagctccc ccaggccgat gagcaccccg aaggcgagcg
    14461 ccgtgcgccc ctcggtgatg ccgtgccaga gggtccaggc gagcgcggtc agggcgagca
    14521 gggcggcgac ggcctgggcg agcgccgcgg gcaggcgtcc cggccggtcc tcgctcgcgg
    14581 gcggctcggc ggccggggcg gcgccggcgc gctccgggcc gccggacgcc gccgcgaggg
    14641 cggtcaccgg gccgctgggc cggacgccga gggcgccggc agctcaggcg gtacgtttcc
    14701 gcgctggtca ccgagctgat cgggcacccg gccggggagg tcggaagtga ccccgggatg
    14761 ccagccgtgc cggtcgagcg cccgcgtcag ggcggcgacc atcaccggat cgaagtgcgc
    14821 ccccgcacag cggtccagct cctccagcgc caccgccacg ggcctggccc tgctgtagga
    14881 ccgcgtggac gtcatcgcgt cgaaggcgtc ggccacggcc accacgcggg cgctctcggg
    14941 gatctgccgc ccggcgagtc cgtaggggta ccccgtgccg tcgatccgct cgtggtggtg
    15001 caggatcgcc tcccgcgcct ccccgaggaa gccgatgccg cgcaccatct cgtggccgta
    15061 ctcggggtgc agctcgatga cgcgccgctc ctcgggcgtc agggggccgt ccttgcgcag
    15121 cagccgggtc ggcaccccga gcttgccgac gtcgtgcagg attccggcga accgcaggac
    15181 ctcgacgcgg tcgtcgtcca tgcccagctc ctcggcgatc agcacggagg cgcggccgac
    15241 ccgctcgctg tgcccgcggg tgtaccggtc cttcaggtcg accgcctgga cgagcgcccg
    15301 gatggtcgcc tggtgggcgg cccgctcgtg gtggtactgg gcgaaggccc agcaggagac
    15361 gcccatcggc agcaggacga gcagcgcggc gggcggcccg taggggctgg tccacaggac
    15421 ggccatcatc agcccggcga ggccgtgcac ggccacgggc gcgagcgagc gcgcgaagag
    15481 gccccgccac gcggtccgcg cgggcacccg ctccgcggtg gcgaggatgc cgccgtccag
    15541 gacggtgagc acgcaggcga aggcgagcac ggcggccccc gcgggcccga gcacgtaggg
    15601 gaagtccggc gcggcggtgg ccgcgggccc gccgagggcc gcgtagagcc gcgcggaggt
    15661 ccaggaggcg agggcgagct gcgccgcgcg ccagacgcgc cgcacccacc gggggcgccg
    15721 gtcggcgcgg gcgagcagcg cccccggcac ggcgaccagc gcggcggcgg ccggcggcag
    15781 caggaagacc ccggcgagca gcacggggaa gagggtgccg gggccgcgcg gcgcacgacg
    15841 gcgcgcggcg gcgcccgtcc tgcccgcgag gcggtccagc agggcctcgt gctcgcaccc
    15901 ggcgtagagc accgcgagga gcgccaccgc gggccagggg gtgtgcgggc ccagggcgga
    15961 cacggcgcag gaggcgccgg ccagggtgac gcacaggatg taagcgcggg cccacatcgg
    16021 caccgaccgc atggaggtct cctccctatg tgcaggtcgg agactaggtg cgcggcccat
    16081 cggtccggtt cccgtccgcg gggaattagc accttcgggt gacgggaggg gaacgggagg
    16141 acgggcggcg ggggaacagc gaagcaggcc gcgcggaacg cgcggcctgc tgctgactac
    16201 ggtcgccggg cgccgcccgg cggggcgttc acgcctcgga ggcggtcacg tcctggatga
    16261 cgtcctggtc gggcacggtc tgcccggagc ggatcagatc gatgcgcccc atgaccttcg
    16321 cccgcaggtc gacggggacg tcgtccgagc cgcagcagcg cttgaccagc ttcttgacgg
    16381 cctgttcgag gccgtacttc tccaggcacg gggagcactc ctcgaagtgc gtctcgaact
    16441 tggtgcagtc gctgtccggc atctcgtggt ccaggaactc atagagatgg tccaggacct
    16501 cactgcagtc agtctcgtgc ggctctccgc agctcatgag cccgagcctt tcgttccgtt
    16561 cgactttccg gcaccggccg ggacgagccc gcgctcacgg gcgtagtcct ccagcatgcc
    16621 gcgcagctgg cggcggccac ggtgcagacg ggacatcacc gtgccgatgg gtgtccccat
    16681 aatgtccgcg atctccttgt acgcaaagcc ctcgacgtcc gccagataga cggcgatgcg
    16741 gaattcctcg ggaatcgcct gcagggcctt cttcacgtcc gagtcgggca ggtggtccag
    16801 cgcctgcgac tcggcggagc gcagaccggt ggacatgtgc gactcggccc gcgcgagctg
    16861 ccagtcctcg atctcctcgg cggcgctgcg ctgcggctcg cgctgcttct tgcggtagga
    16921 gttgatgaac gtgttggtga ggatgcggta gagccaggcc ttgaggttgg tgccctcacg
    16981 gaactggtgg aacgacgcgt acgccttggc gtacgtctcc tgcaccaggt cctccgcgtc
    17041 cgccgggttg cgcgtcatgc gcagcgccgc cgagtacatc tgatccagga aggtcagtgc
    17101 gtcccgctcg aagcgggccg tgcgctccgc ggccgtctcg gacctctccg gattctctcg
    17161 gggctgctcc gcctgaccgt gctcggtccc cgcgtcggtc ccagtgaccg gacccacctc
    17221 ctccaacgac gtggcgaggc cgaaagcagc cccactcgaa tcggaggata gacgacgatc
    17281 cgctccgcgc gccgcccgaa taggtgcgct tttgggtgcg ctcagtaccg tccactccag
    17341 gtcagaggcg ctggagcggt tcgggcagat ggtcggaccc atgcggcgga ctccctctcg
    17401 tacgaacagg tcgacgacgg tgttcaccgt ctgttcgcga caacagaggt cacgcgtcca
    17461 acattcccgt ccagcgcacc acggcgtccg tgacgcgctt cacggcctcg tcctggccga
    17521 tctccgcccg cttgggcacg gcgaaaccgt ggtcggcgta cgggacttcc gccagctcgt
    17581 agccgtcgcc ggccgggaac tcggcgggcc tgccgaacgg gtcgttgccg ccctgcacga
    17641 cgagtacggg cacgcccgcg ccgagcagtt cgtcggcgcg cgacttctcc ggcttgcccg
    17701 gggggtgcag cgggaagctg agggcgagca cggcggcggc gccgagctcg gccgcggtgc
    17761 ggcaggcgac gcgggcgccc gcgctgcggc ccccggagat cacgggcagc ccccgctccg
    17821 ccagcgcggg ccagatgccc cgccacccgg cgtccagcgt cctgggcgcg ggcgccagct
    17881 tcttgcccgc cacccgccag ggctgctcca cgagggccac ggtcactccg tgggcgggca
    17941 gctcggccgc gagcgccttc aggtccctgg cctcgatgcc gccgcccgcg ccgtggctga
    18001 cggccagcag gaggcgcggc tcccgtgccg tgcgccaggt gatccgcgcc gtaccggtgt
    18061 cggtctcgat ggtctcgacg ggcccggtgc tctcgccggg cccgctgcgt gtctcgtgcg
    18121 tcacgtcaga agagtgtgcc ctcttccggt ccgtccagct ccttcagcag ctccgggccg
    18181 ttgttgcgca cgttgctgac ggccgtcgac accgggaagg cccgcatcag tccgtgcggc
    18241 ggcggctcca ggagggggcg caggtcctcg acgtccgtgc gggacgggtc gagccaggcg
    18301 tcccagcggt ccggggtgag catcagcggc atccgcgggt ggatgtcggc gagcgagcgc
    18361 gggccctgtg cgggagcgac ggccagcggc gcggtctcgg cctccgtggt gatcaccgtg
    18421 caggtcaccc accaggcgag ggggtgctcg tcggggagcg tcttgtcccg ccagaactcg
    18481 aagagccccg ccatggcgaa gacggagccg tcggcgggcg tcacgaagta cggctgcttg
    18541 cgggggcgct tcttcttgcc ctcgacctcc agctgccgct cctcgggcgc ggtgacccac
    18601 tcgtagtagc cgtcggccgg gatgacgcag cggcgggagg cgaaggcgcg gcggtaggag
    18661 ggcttctcgt gcacggtctc ggcgcgggcg ttgatcatcc gggccccgcc ctcgggcgtc
    18721 ttggaccagg agggcacgag gccccacttc agggtgcgca gctggcgaac cggagcgggg
    18781 tcgtcggcgt ctttcagggg acggtcgaga acggcgtaga cctctttggt cggcgccacg
    18841 ttgtagtcgg gggccagggc ctcctccggc tcgtacttct cgatctcgaa gatccccgcg
    18901 agatcctccg gcccacgact cgatgcatac cgtccgcaca tacgtgccag actgccaggc
    18961 ccacccgtca cccgaccacc acttctcaac ggtgcgcccc gcgcagcacc tccttgcccc
    19021 ctaggagtca gtcccagcaa tggatcaagg actcgagacc gccgccgacg ccagcctgac
    19081 ggacctctgg gaccggatcc tcggtacgca ggcggcgccc gagacatggc tggtcatagc
    19141 caccggcgtc gtcgcgctgg ccgtggtcgt gccgcatggc gtctggcggc tcgcccgcaa
    19201 cgccatcacg atcgcgcacg agggcggcca cggccttgtg gcgttgctca ccgggcggcg
    19261 cctcgacggc atccggctgc actccgacac ctcggggctg accgtctcgc ggggcaggcc
    19321 cagcggcatc ggcatgatcc tcaccgcggc ggcgggctac acggccccgc cgctgctcgg
    19381 cctcggcggc gcggcgctgc tcggctcgag gcgcatcacg gcgctcctgt ggatcgccac
    19441 cgcgctgctc gtcgcgatgc tggtgatgat ccgcaacgcg tacggcgtcc tgacggtcgt
    19501 cctcaccggc ggcgccttcc tgctcgtctc ctggctggcc ggctccgagg tgcaggcggc
    19561 gttcgcgtac gcggtggtgt ggttcctgct cctcggcggt gtgcggcccg ccttcgagct
    19621 gcagtccaag cgcaggcgcg ggggcgcggg cgattcggac gcggatcagc tctcacggct
    19681 cacgcacgtc cctgccgggc tctggctctt cttcttccac gccgtctcgc tctgctcgct
    19741 gatgggcggg gcccgctggc tcctcgccgt ctgagcgggg ccgctgacag cccttaaagt
    19801 gagggcatga ccgaaacccc ggcgaacacc gccctctggc ccgccccgca cgcaagcgga
    19861 gccgtcaccg cgacggtcca cgtacccggt tcgaaatcgg tcaccaaccg ggcgctcgtc
    19921 ctggccgcgc tcgccgccga gcccggttgg ctgcgccgcc cgctgcgctc ccgcgacacc
    19981 ctcctgatgg ccgacgcact gcgcgccatg ggcgtcggca tcgaggagac cgtctcctcc
    20041 agctccaccg tggccggcgc ccccgagggc tccggcgagg cctggcgcgt gatcccctcg
    20101 gggctgcacg gccccgccac ggtcgacgtc ggcaacgccg gcacggtcat gcgcttcctc
    20161 cccccggtcg ccgccctcgc cgacggcccg atccgcttcg acggcgaccc ccgttcgtac
    20221 gagcggccgc tgaccggtgt gatcgacggc ctgcgggtgc tcggcgcccg catcgacgac
    20281 gacaaccgcg gcgcgctgcc cctgacggtg cacggcgccg gggcgctgga cggcggctcc
    20341 gtcgagatcg acgcctcgtc ctcctcgcag ttcgtcagcg ccctgctgct ctcggccccg
    20401 cgcttcaacc agggcgtgga ggtgcgtcat gtggggggcg ccctgccctc catgccgcac
    20461 atccggatga cggtggacat gctgcgcgcg gtcggcgccc aggtggacac ccccgaggcg
    20521 ggcggcgagc ccaacgtctg gcgggtcacc cccggcgcgc tgctgggccg tgacctgacc
    20581 atcgagcccg acctctcgaa cgcgcagccg ttcctcgccg cggccctggt caccggcggc
    20641 acggtcacca tccccgactg gcccgcgcac accacgcagc ccggcgacgc gctgcgggag
    20701 atcttcaccg agatgggcgg ttcctgcgaa ctgacgcagg cgggcctggt gttcaccggc
    20761 acggggtcca tccacggcct cgacgtggac ctcagcgagg tcggcgagct gacgcccggc
    20821 atcgcggcgg cagcggccct cgccgactcg ccctccacgc tgcgcggcgt cgcccacctg
    20881 cggctgcacg agacggaccg cctggccgcg ctcaccaagg agatcaacga actcggcggc
    20941 gacgtcaccg agaccgccga cggcctgcac atccgtccgc gcccgctgca cggcggcgtc
    21001 ttccacacct acgacgacca ccgcatggcg accgcgggcg cggtgatcgg cctcgcggtg
    21061 gacggcgtgc ggatcgagaa cgtcggcacg acggcgaaga cgctcccgga ctt
//
