LOCUS       NZ_CP015588            13060 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces alfalfae strain ACCC40021 chromosome, complete genome.
ACCESSION   NZ_CP015588
VERSION     NZ_CP015588.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces alfalfae
  ORGANISM  Streptomyces alfalfae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8625867)
  AUTHORS   Gu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2016) Institute of Agricultural Resources and
            Regional Planning, Chinese Agricultural Academy of Sciences, 12
            Zhong Guan Cun South Street, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SOAPdenovo v. 2.04; Celera Assembler v. 8.0;
            GapCloser v. 1.12
            Genome Coverage                   :: 310.8
            Sequencing Technology             :: Illumina; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 02:19:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,535
            CDSs (total)                      :: 7,444
            Genes (coding)                    :: 7,210
            CDSs (with protein)               :: 7,210
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 107 of 234
            Pseudo Genes (incomplete)         :: 177 of 234
            Pseudo Genes (internal stop)      :: 26 of 234
            Pseudo Genes (multiple problems)  :: 73 of 234
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:53:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1518679
            Orig. end                         :: 1531739
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015588.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13060
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="10"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13060
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13060
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8060](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8060
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(30..2360)
                     /locus_tag="A7J05_RS06145"
                     /old_locus_tag="A7J05_05805"
     CDS             complement(30..2360)
                     /EC_number="3.4.24.3"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004940664.1"
                     /locus_tag="A7J05_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05805"
                     /product="collagenase"
                     /protein_id="WP_076683327.1"
                     /transl_table=11
                     /translation="MFRLRPRTLRRSVLAGVLAASLCVTAAPLSAHAADSAAPARATAA
                     EPDSRDVVERRASAPDPAARALAAPGRLKKGQVPGPRTPKPKAEQRAKGQDGPATAPCT
                     LDGVTSLGPEAFADFLADPAVTAEGCLRTLIWTWDRRLAPVMSDAHVQAVSGRVSRLAA
                     THDGRNGTNLLELLTYLHAVAYQDFSHDEIDVTDGPTVDAMRRAVAAFGAAPRTFDATG
                     ANADCLREALYAASAPGLRQHQLPLVKKVLATMDADHPGTAKDAAWGGSALAALSLNYL
                     GVYPGNRDTAFHAAAKADPAYRAAFKAFAGHTHLKGTGNASVVRDALSEYGRFGQIDGV
                     RSETVSGLGGLVAVTARDFGEGSGPWVKVATWLNEYDACAPYGVCRADIERRIFPHTYT
                     YDKGGMKVRTALGRGAVDQLYYASKQVKAQFHRVLGADEPLAGDPNTGLTTVLYASRAD
                     YENYHPLLTGMGTDNGGVYIERGATFYTYQRRVPQDSTLTLEELFRHEYTHYLNGRWAV
                     PGFFGEGPWYENDRTTAMDEGTAEFFAGATRDDGVKVRKALVRGIIDDTANGGPRMTVR
                     QILHATYDGDGFRFYDYAGTFFEFLWAERPSLLKEMYRHLRADDPAAFDAWRDRLGGDG
                     AVQRAYDAFLDEQIAHVDDLFVPDTTYVPVGELRDSTAAQVRTSFRSATGVTPECRSNG
                     APDRPRYLCGGRVTANLSASDDPDAVFEDMSETVDHYLLDRAAAGGRHNNLTDMNCSFG
                     EVDVWSDGRAGSADFACEGPLRS"
     misc_feature    complement(2349..2351)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    2488..2504
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.23"
                     /tool="antismash"
     misc_feature    complement(2496..2512)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    complement(2498..2508)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(2611..3750)
                     /locus_tag="A7J05_RS06150"
                     /old_locus_tag="A7J05_05810"
     CDS             complement(2611..3750)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151712.1"
                     /locus_tag="A7J05_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05810"
                     /product="MFS transporter"
                     /protein_id="WP_076688621.1"
                     /transl_table=11
                     /translation="MVLLALAHACVDLYQGAVAALVPFFVAERAYTYAAASGVVLAASL
                     LSSVVQPVFGALTDRWAMPWLLPVSTLVGGIGVALAGLTGSYALTLAVVGLSGIGVAAY
                     HPEAARVARRASRGSHAAMSWFSLGGNLGFATAPLLVSAIAASGGLGASPLLVVPALAG
                     AVLCVAALRGVKAVEAATPKGVHREPGADDWPSFLRLSGAIVCRSIVFVGLGAFISLYA
                     RQRTGGGEAAGTAALFVLYIGGALGTVAGGRLAALFGRVPVVRWSYALTVPAVAGVVLV
                     PGPLFHVFVLLTSAGLYVPFSLHITLGQDFLPRRVGTAGGVTLGLTVSVGGLASPLIGA
                     LADATSLRTALAPLIALPALGWLLLRTLREPDGEAPRRA"
     gene            4167..4925
                     /locus_tag="A7J05_RS06160"
                     /old_locus_tag="A7J05_05815"
     CDS             4167..4925
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151713.1"
                     /locus_tag="A7J05_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05815"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_076683331.1"
                     /transl_table=11
                     /translation="MPENRRTIRHTPEAPTDTRSLAPGESIDAHRHDNHQIIYAGSGVV
                     AVTTDAGTWFAPGTRAIWVPAGCVHAHRAHGHLALHLLGLPADANPLGLDAPAVLTVSP
                     LLRELILACTRAPHEDTPERRRLRAVLLDQLRVSPQQPVQLPTPKDPRLAAVCGQLHRD
                     PADPRGLAELAATAGAGERTLSRLFRRELGMTFPQWRTQLRLYHALRMLADGVAVTTVA
                     HRCGWASASAFIDVFRRSLGYTPGAHQRGD"
     misc_feature    4985..5001
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            5001..6188
                     /locus_tag="A7J05_RS06165"
                     /old_locus_tag="A7J05_05820"
     CDS             5001..6188
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891271.1"
                     /locus_tag="A7J05_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05820"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_076683333.1"
                     /sec_met_domain="DAO (E-value: 3.7e-70, bitscore: 236.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRHPSGPPDFSDVIVVGAGMIGAACAHYASRAGLHVTVVDRGP
                     VAGGTTGAGEGNLLVSDKEPGPELRLALLSTRLWTELAAESPPDIEYERKGGLVVASTE
                     AELTALRALAAEQRRAGVTAADVPADRLADHEPHLAPDLTGGCHYPQDAQVQPALAAAH
                     LLRAAVGTGRLSLRLGEEVTAVLTEKGGAVRGVRTAKGEIRAPHVVNATGAWGGRLARM
                     AGVELPIRPRRGFVLVTEPLPRLVRHKVYSAEYVADVASGSAALQTSAVVEGTQAGPVL
                     IGASRERVGFDRALSVEALRRLASQATRLFPALARARALRAYAGFRPYLPDHLPAIGPD
                     PRVPGLLHACGHEGAGIGLAPATGLLITGFLTEAEPPLDPSPFAPERFAREPAPP"
     gene            6260..6580
                     /locus_tag="A7J05_RS06170"
                     /old_locus_tag="A7J05_05825"
     CDS             6260..6580
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="A7J05_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05825"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_076683335.1"
                     /sec_met_domain="Fer2_4 (E-value: 7.3e-24, bitscore: 82.4,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQADRTTPADLVGATDATHFFTFDGRRVAARPGQSIAAALWTAG
                     ILAWRETRGAARPRGAFCGIGQCHDCLATVNGRPNRRACLVTARPGDEVTTQKGHGHAE
                     PR"
     gene            6564..8060
                     /locus_tag="A7J05_RS06175"
                     /old_locus_tag="A7J05_05830"
     CDS             6564..8060
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091457.1"
                     /locus_tag="A7J05_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05830"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_076683337.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.3e-22, bitscore:
                     76.7, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 3.8e-10, bitscore:
                     38.8, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPGDPYDVAVLGAGPAGLAAAVTAAEQGLTVALLDAAQQPGGQ
                     YYRHPAPAARATRPDALHHDWRVFAGLRERLDAAEGVTRLYGHHVWSMTREAPGSPWSL
                     HALTGEGDDDDASAPGTGTTVQARAMLLATGSHERHLPFPGWTLPGVVSAGGAQAMLKS
                     GLALPGTRVVVAGSGPLLLAAATSLAAAGADVPEVIEASGYLGYARHPAALAANPGKLT
                     EAARHGAALLRHRVRPRTRSAVTEAHGADRVEAVTVSRLGRDWRPVPGSERRVACDALA
                     VGHGLVPRTELATTLGCATRRAADGTYALELGPLQETSLRGLWAAGETSGVGGAQAALV
                     EGELAALAITARLTGRRPAPARRLRALRRRRDHLRAFADAMAAAHAPGPGWTRWLGDDT
                     EVCRCEEVTAARVREAVADYGARDPRSVKLLTRAGMGWCQGRVCGTAVACLAAAAPDAT
                     PAPPDRRLLATPVPLGTLASLTPADPPPAAPDDPSEGHPS"
     gene            8057..8980
                     /locus_tag="A7J05_RS06180"
                     /old_locus_tag="A7J05_05835"
     CDS             8057..8980
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237885.1"
                     /locus_tag="A7J05_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05835"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_076683339.1"
                     /transl_table=11
                     /translation="MTTTHPLTAAWSPSRPWRGIMVATALPLRDDLSVDYDAYAAHVAH
                     LLANGCDGVVPNGSLGEYQTLTDDERERVVRTAVEAAGDGARVMPGVSAYGSAESRRWA
                     EQAADAGCGSVLLLPPNAYRADERAVRAHYTEVAGAGVPVVAYNNPLDTRVDLTPELLA
                     RLHGDGAVVAVKDFSGDVRRAYETAELVPDLDLLVGADDVLLELALAGAVGWIAGYPNA
                     FPAACAELYRAACAHDLETALPLYRALHPLLRQDSGTEFVQSIKLSMDLAGRRGGPTRP
                     PRLPLGGPAEALVRAATEKALAAGHR"
     gene            9027..10031
                     /locus_tag="A7J05_RS06185"
                     /old_locus_tag="A7J05_05840"
     CDS             9027..10031
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="A7J05_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05840"
                     /product="proline racemase family protein"
                     /protein_id="WP_076683341.1"
                     /transl_table=11
                     /translation="MRTRHVFHAVDSHTEGMPTRVITGGVGVIPGATMADRRLHFIEHL
                     DHLRTLLMHEPRGHSAMSGALLQPPTRPDADYGVLYIEVSGVLPMCGHGTIGVATVLVE
                     TGMVPVTEPVTTVRLDTPAGLIRVDVSVTDGAATSATLTNVPAFCVALDRKIDVPGHGT
                     VTYDLAFGGNFYAFAHLDALGLPFTRDRKDDLLAAGLAVMAAINASPDRPVHPEQPDIA
                     GLKHVYLIAPGSDAHRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLERDFVNE
                     SFIGTEFTGRLIGRTEVAGLPAVVPRITGRAWLTGTAQYFLDPDDPFPAGFAL"
     misc_feature    complement(10101..10111)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            10183..10860
                     /locus_tag="A7J05_RS06190"
                     /old_locus_tag="A7J05_05845"
     CDS             10183..10860
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608085.1"
                     /locus_tag="A7J05_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05845"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_076688623.1"
                     /transl_table=11
                     /translation="MGHLKQKNLITARERLRDQVAHALRAALISGELRPGEIYSAPGLA
                     EDFGISATPVREAMLDLAREGLVEPVRNKGFRVTEVNERDLDQYTEIRLLIEVPMIGRI
                     TRTAAREDLEVLRPIADEIVRAAREHDLIGYLEADRRFHLSLLALSGNDRLVETVGDLR
                     KRSRLYGLTTLDARDQLTPSAEEHGELLDLMLTGDANAAEECMARHLGHVRSLWAQGAA
                     EGA"
     tRNA            complement(10925..11012)
                     /anticodon=(pos:complement(1529656..1529658),aa:Leu,
                     seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="A7J05_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="A7J05_05850"
                     /product="tRNA-Leu"
     gene            complement(10925..11012)
                     /locus_tag="A7J05_RS06195"
                     /old_locus_tag="A7J05_05850"
     gene            complement(11166..12206)
                     /locus_tag="A7J05_RS06200"
                     /old_locus_tag="A7J05_05855"
     CDS             complement(11166..12206)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378305.1"
                     /locus_tag="A7J05_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7J05_05855"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_076683343.1"
                     /transl_table=11
                     /translation="MNRKTTSADPELAHRLSRRGMLGVAAGATAAALVGGAAAPAAAGE
                     KGRGRPVLPPGRLGIQLYSLRDKISTLGFAPVFAELEKYGYDEIEFAGYTQGSAGAITL
                     AQLKALARDHGLHPIGSHVGYYDDNNPGAYTFAQNLDKVLDDAEALGLKHIGTASGPFR
                     YGSTVDGWKRAAEDFNTYGEAARKRGMKFYQHNHAEEFSFATDKPKVRLYDVLLAETDP
                     DFVYLEMDIYWAFCAQFRFSKRPDGRPARLDPLDYVLKQPHRYPLFHVKDGVRDETTRD
                     GYRMSDVGDGDIDYKRFLSKVTARTPQGRRYHHWQTEHDNPVDSLAFARKSSEHLHSLR
                     SGRCGD"
     misc_feature    12209..12223
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.37"
                     /tool="antismash"
ORIGIN
        1 ggcgcgaccg cctgacaggg gctgccgggt cagctccgca acggaccctc gcaggcgaag
       61 tccgcgctgc cggcccggcc gtcgctccag acgtccacct cgccgaacga gcagttcatg
      121 tcggtgaggt tgttgtgccg cccacccgcg gcggcccggt cgagcaggta gtggtcgacc
      181 gtctcggaca tgtcctcgaa gacggcgtcc gggtcgtcgg aggcgctgag gttcgcggtg
      241 acgcggccgc cgcagaggta acgcggccgg tccggcgccc cgttggagcg gcactcgggc
      301 gtgacacccg tcgccgacct gaacgaggtg cggacctggg cggcggtgct gtcccgcagc
      361 tcgccgaccg ggacgtacgt cgtgtccggc acgaagaggt cgtcgacgtg cgcgatctgc
      421 tcgtcgagga aggcgtcgta cgcgcgctgc accgcgccgt ccccgccgag ccggtcgcgc
      481 caggcgtcga aggccgccgg gtcgtcggcg cgcaggtgcc ggtacatctc cttcagcagg
      541 ctcggccgct ccgcccacag gaactcgaag aacgtccccg cgtagtcgta gaagcggaag
      601 ccgtcgccgt cgtacgtggc gtgcaggatc tgccggacgg tcatccgggg accgccgttc
      661 gccgtgtcgt cgatgatgcc ccgcaccagc gccttgcgga ccttcacgcc gtcgtcgcgc
      721 gtcgctccgg cgaagaactc ggccgtcccc tcgtccatgg cggtggtccg gtcgttctcg
      781 taccaggggc cctcgccgaa gaagccgggg accgcccagc ggccgttgag gtagtgggtg
      841 tactcgtggc ggaagagttc ctccagcgtg agcgtggagt cctggggcac gcgccgctgg
      901 taggtgtaga aggtcgcgcc ccgctcgatg tacacgcctc cgttgtcggt gcccatgccg
      961 gtgagcaggg ggtggtagtt ctcgtagtcg gcgcgggagg cgtagagcac ggtcgtcagg
     1021 ccggtgttgg ggtcgcccgc cagtggctca tcggcgccga ggacgcggtg gaactgcgcc
     1081 ttgacctgct tgctcgcgta gtagagctgg tcgacggcgc cccggcccag cgccgtgcgg
     1141 accttcatgc cgcccttgtc gtaggtgtac gtgtgcggga agatgcggcg ctcgatgtcc
     1201 gcccggcaga cgccgtacgg cgcgcaggcg tcgtactcgt tcagccaggt cgcgaccttc
     1261 acccagggcc cgctgccctc gccgaagtcg cgtgcggtca cggcgacgag gccgccgaga
     1321 ccgctgacgg tctcgctcct gaccccgtcg atctgcccga acctgccgta ctcactgagc
     1381 gcgtcccgca ccaccgaggc gttgcccgtg cccttgagat gggtgtgccc ggcgaacgcc
     1441 ttgaaggccg cgcggtaagc cgggtccgcc ttggccgccg cgtggaaggc ggtgtcccgg
     1501 ttgccggggt agacgccgag gtagttcagg gagagcgcgg cgagcgcgga cccgccccag
     1561 gcggcgtcct tcgcggtgcc ggggtggtcg gcgtccatgg tcgccaggac cttcttgacg
     1621 agcggcagtt ggtgctgccg cagccccgga gcgctcgccg cgtacagcgc ctcgcgcagg
     1681 cagtcggcgt tggcgccggt cgcgtcgaac gtgcggggcg ccgcgccgaa ggcggcgacg
     1741 gcgcggcgca tggcgtcgac ggtggggccg tcggtgacgt cgatctcgtc gtgcgagaag
     1801 tcctggtagg cgacggcgtg caggtaggtg agcagttcca ggaggttggt gccgttcctg
     1861 ccgtcgtgcg tggcggcgag ccggctgacg cgtccggaca ccgcctggac gtgggcgtcc
     1921 gacatcacgg gggcgagccg ccggtcccag gtccatatga gggtccgcag acagccttcc
     1981 gcggtgacgg cgggatcggc gaggaagtcg gcgaacgcct cgggcccgag cgaggtgacg
     2041 ccgtcgagag tgcagggcgc ggtcgcgggc ccgtcctggc ccttggcccg ctgctcggcc
     2101 ttcggcttcg gcgtacgggg cccggggacc tgccccttct tgaggcgacc gggcgcggcc
     2161 agcgcgcggg cggccggatc gggggcggac gccctgcgct cgacgacgtc acgggagtcg
     2221 ggctcggcag ccgtcgcacg ggcgggggcg gcgctgtcgg ccgcgtgggc ggagaggggc
     2281 gcggccgtga cgcagaggct cgcggcgaga acgccggcga ggacggatct gcgcagggtt
     2341 cttgggcgta accggaacat cggggctcct gtgtgggagg tgtggggtgt gacggcccga
     2401 gggcgcacaa ctgccgcgcc gggcagcacg tttggcggct ccgggacggc ggcctcgcga
     2461 ggacccgtcc gggccatgtg atgcgtaacg tagtaatgtg aaattgcact gacaacccct
     2521 cagacaccga attcgctggg gcgcgaggtc cttgcggtgc ttcgggggcg gggaccgaaa
     2581 gggtccgcgc ttcaggcgcg acgcggggct tcaggcgcga cgcggggctt cgccgtccgg
     2641 ttcgcgcagt gtgcgcagga ggagccaacc gagcgcgggc agcgcgatga gcggcgccag
     2701 ggcggtccgc agggacgtgg cgtcggcgag ggcgccgatc agcgggctcg cgaggccgcc
     2761 cacgctcacg gtgaggccga gtgtgacgcc acccgcggtg cccaccctgc gcggcaggaa
     2821 gtcctggccg agggtgatgt gcagggagaa cggcacgtag agcccggccg aggtgagcag
     2881 gacgaagacg tggaacaagg gtccgggtac gaggacgacg ccggccaccg cggggaccgt
     2941 cagggcgtac gaccaccgca ccaccgggac gcgcccgaac agcgcggcga gcctgccgcc
     3001 cgcgacggtg ccgagggcgc cgccgatgta gagcacgaac agggcggccg tgcccgcggc
     3061 ttcgccgccc ccggtgcgct ggcgcgcgta cagcgagatg aaggcgccga gcccgacgaa
     3121 gacgatcgag cggcagacga tggccccgga gagccggagg aaggagggcc agtcgtcggc
     3181 gccgggctcc cggtggaccc ccttgggcgt cgccgcctcg acggccttca cgccccgcag
     3241 cgcggcgacg cagagcacgg ccccggcgag ggcgggcacc acgaggagcg gtgaggcgcc
     3301 gaggccgccg gaggcggcga tggcggagac cagcagcgga gcggtcgcga agccgaggtt
     3361 gccgccgagg gagaaccagc tcatggccgc gtggctgccg cggctcgccc gccgggccac
     3421 gcgggccgcc tcggggtggt acgcggccac gccgatgccg gagaggccga cgaccgcgag
     3481 cgtcagggcg tagctgccgg tgagcccggc gagggcgacg cctatgccgc ccaccagcgt
     3541 gctcacgggc agcagccagg gcatggccca ccggtcggtg agcgccccga acaccggctg
     3601 caccacggag gagagcagcg aggcggcgag gacgacgccg gaggcggcgg cgtaggtgta
     3661 ggcgcgctcg gccacgaaga aggggacgag ggcggcgacg gcgccttggt agaggtccac
     3721 gcaggcgtgg gccagggcga ggaggacgat ggggcgacgg gccggcgggg ccttgccctc
     3781 gggaggcgtg ggggcctcgg tgccgggagc ggccgaggct ccggttgccg ccacggccgg
     3841 ggccggcctc gtatcctccg ggtgagtgca cgtgccgacc tccgggcgaa gggccttgtc
     3901 ggcctccggg cgagggccct tatcggccgc cgggcgaggg cgcgtgccgg actccgggcg
     3961 agggcgcgtg ccggactccg ggtgagtgcg cgtgtcggcc gccgggcgag ggcgcgtgcc
     4021 ggactccggg cgagggcgcg tgccggactc cgggcgacgg gccttgtcgg cctccgggca
     4081 gggcagttcg ctcgtgggtt ccatcgttga catcactcca tcgtcgccac gcgacccctg
     4141 gcgcgcttcc gataaagtgc cgacccatgc cggaaaaccg ccgcacgatc cgccacaccc
     4201 ccgaggcccc cacggacacc cggtcactgg cgcccggcga gtccatcgac gcgcaccgcc
     4261 acgacaacca ccagatcatc tacgcgggtt ccggcgtcgt ggccgtcacc accgacgccg
     4321 gaacctggtt cgcgccgggc acccgggcca tctgggtccc cgcgggctgc gtccacgcgc
     4381 accgcgccca cggccacctc gccctgcacc tgctcggcct gcccgccgac gccaacccgc
     4441 tcggccttga cgccccggcc gtcctcaccg tcagcccgct gctgcgcgaa ctgatcctcg
     4501 cctgcacgcg tgccccgcac gaggacaccc cggagcgccg gcgcctgcgc gcggtgctcc
     4561 tcgaccagct ccgcgtctcc ccgcagcagc ccgtccagct gcccaccccc aaggaccccc
     4621 gcctcgccgc cgtctgcggg caactgcacc gcgaccccgc cgacccgcgc ggcctcgccg
     4681 aactggccgc aaccgccgga gcgggtgagc gcaccctcag ccgcctcttc cgccgcgagc
     4741 tcggcatgac cttcccccag tggcgcaccc agctccgcct ctaccacgcc ctgcgcatgc
     4801 tggccgacgg cgtggccgtc accacggtcg cgcaccgctg cggctgggcg tcggccagcg
     4861 cgttcatcga cgtgttccgc cgctcgctcg gttacacccc gggcgcccac cagcgcggcg
     4921 actgaagcga ccgccagacc ccaactcctc gtggcgcacg ccctcttggc agccttagtg
     4981 ccatgtgaaa tattactgct gtgctcacga gacacccctc cggaccaccg gatttctcgg
     5041 acgtcatcgt cgtgggagca gggatgatcg gcgccgcctg cgcccactac gcctcccgcg
     5101 ccggcctcca cgtcaccgtc gtcgaccgcg gccccgtcgc gggcggcacc acgggcgcgg
     5161 gtgagggcaa cctcctcgtg tccgacaagg aaccgggccc cgagctgcga ctcgcgctgc
     5221 tctccacccg gctgtggacc gaactcgccg ccgagtcccc gccggacatc gagtacgagc
     5281 ggaagggcgg cctggtcgtg gcctcgacgg aggcggaact gaccgccctg cgggccctcg
     5341 cggcggagca gcggcgcgcg ggcgtgacgg cggccgacgt ccccgccgac cgcctcgccg
     5401 accacgaacc ccacctcgcg cccgatctca ccggcggctg ccactacccg caggacgcgc
     5461 aggtgcagcc ggccctggcc gcggcccacc tgctgcgcgc cgcggtcggc acgggacgcc
     5521 tgtcgctgcg gctcggcgag gaggtcacgg cggtgctgac ggagaagggc ggcgcggtgc
     5581 gcggcgtccg gaccgcgaag ggcgagatcc gagcccccca cgtggtcaac gcgaccggcg
     5641 cctggggcgg tcgactggcc cgcatggcgg gcgtggagct gccgatacgc ccccgccgcg
     5701 gcttcgtcct ggtcaccgaa cccctgccgc gcctggtgcg gcacaaggtg tactccgcgg
     5761 agtacgtcgc cgacgtggcg agcgggtcgg cagccctgca gacgtccgcc gtggtggagg
     5821 gcacccaggc gggcccggtg ctgatcgggg cgagcaggga acgggtcggc ttcgaccgcg
     5881 cgctctcggt ggaggcgctg cggcgcctgg cgtcccaggc gacccggctg ttcccggccc
     5941 tcgcccgggc ccgcgcgctc cgcgcctacg cgggcttccg cccctacctc cccgaccacc
     6001 tccccgccat cggccccgac ccccgggtcc ccgggctgct gcacgcgtgc ggccacgagg
     6061 gcgcgggaat cggcctcgcc ccggcgaccg gcctgctgat caccggtttc ctgacggaag
     6121 ccgagccccc gctcgatccg tcgcccttcg ccccggaacg cttcgcccgc gagccggcgc
     6181 cgccgtgagg cggctccggg agacgagcac gccatggccg ccacagcggg gaagccgccg
     6241 catgagagga gccgccccca tggggcaagc cgacaggacg acgcccgcgg acctcgtggg
     6301 cgcgaccgac gccacccact tcttcacctt cgacggccgc cgcgtcgcgg cccggccggg
     6361 ccagtccatc gccgccgctc tctggacggc gggcatcctc gcctggcggg agacccgggg
     6421 cgccgcccgg ccgcgcggag ccttctgcgg gatcggccag tgccacgact gcctggccac
     6481 cgtcaacggc cgccccaacc gccgcgcctg cctggtgacc gcccggcccg gcgacgaggt
     6541 caccacgcag aagggccacg gccatgccga gccccggtga cccgtacgac gtggcggtcc
     6601 tcggcgcggg gccggcaggc ctcgccgcgg cggtcacggc cgccgaacag ggcctgaccg
     6661 tggccctgtt ggacgccgcc cagcagcccg gcggccagta ctaccggcat ccggccccgg
     6721 ccgcgcgcgc cacccgcccc gacgcgctgc accacgactg gcgcgtcttc gccggcctcc
     6781 gcgaacgcct ggacgccgcg gagggcgtca cccggctcta cggtcaccac gtctggtcga
     6841 tgacgcgcga ggcgccgggc tccccgtggt ccctccacgc cctgaccggc gagggggacg
     6901 atgacgacgc gagcgccccg gggacgggta cgacggtcca ggcgcgcgcg atgctcctgg
     6961 ccaccggctc ccacgaacga cacctcccct tccccggctg gaccctcccc ggcgtcgtca
     7021 gcgcgggcgg cgcccaggcc atgctgaagt ccggcctggc cctgcccggc acacgtgtgg
     7081 tcgtggcggg cagcggcccg ctcctgctcg ccgcggccac ctcgctcgcc gccgccggag
     7141 ccgacgtccc cgaggtgatc gaggcctccg gctacctcgg ctacgcccgc cacccggccg
     7201 ccctcgccgc caaccccgga aagctgacgg aagccgcccg ccacggcgcg gccctgctgc
     7261 gccaccgtgt gcgcccgcgc acccgcagcg cggtcaccga ggcacacggc gccgaccgcg
     7321 tcgaggcggt gacggtctcc cgcctcggcc gcgactggcg cccggtcccc ggctcggaac
     7381 gccgcgtcgc ctgcgacgcc ctggccgtcg ggcacggcct ggtcccgcgg accgaactgg
     7441 cgaccaccct cggctgcgca acccgccgcg ccgccgacgg cacgtacgcc ctggaactgg
     7501 gcccgctcca ggagacctcg ctgcgcggcc tgtgggcggc gggcgagacg tccggcgtcg
     7561 gcggggcgca agcggcgctc gtggagggcg agttggcggc cctggcgatc accgccaggc
     7621 tgacggggcg gcggcctgcc ccggcccgcc gcctgcgcgc cctgcgccgc cgccgcgacc
     7681 acctgcgcgc cttcgccgac gccatggccg ccgcgcacgc gccgggcccg ggctggacac
     7741 ggtggctcgg cgacgacacg gaggtgtgcc gctgcgagga ggtgacggcg gcccgggtcc
     7801 gcgaggcggt ggcggactac ggcgcccgcg acccccgtag cgtcaaactc ctcacgcgcg
     7861 ccggcatggg ctggtgccag ggccgcgtgt gcggcacggc cgtggcctgc ctggccgccg
     7921 ccgcgcccga cgccaccccc gcgccgccgg accgccgcct cctcgccacg cccgtccctc
     7981 tgggcactct cgcctcactc accccagcgg acccaccacc cgcagctccc gacgacccct
     8041 cggaagggca cccttcatga cgacgacgca ccccctgacc gccgcgtggt ccccgtcccg
     8101 cccctggcgc ggcatcatgg tcgccaccgc gctccccctg cgcgatgacc tctccgtcga
     8161 ctacgacgcg tacgccgcac atgtcgccca cctcctcgcc aacggctgcg acggcgtggt
     8221 ccccaacggc tccctcggcg agtaccagac cctcaccgac gacgagcgcg agcgcgtcgt
     8281 gcggaccgcc gtcgaggcgg cgggcgacgg ggcccgcgtc atgccgggcg tctccgccta
     8341 cggcagtgcc gagtcccgcc gctgggccga gcaggcggcc gacgcgggct gcggttccgt
     8401 gctgctgctg ccgccgaacg cctaccgcgc cgacgagcgg gccgtacgcg cccactacac
     8461 cgaggtcgcc ggggccggcg tgcccgtggt cgcgtacaac aaccccctgg acaccagggt
     8521 cgacctcacg ccggagctgc tggcccggct ccacggcgac ggagccgtcg tggcggtgaa
     8581 ggacttcagc ggcgacgtgc gcagggcgta cgagacggcc gaactcgtcc cggatctcga
     8641 cctcctcgtc ggcgccgacg acgtgctcct cgaactggcc ctcgcgggcg cggtcggctg
     8701 gatcgccggt tacccgaacg ccttccccgc cgcctgcgcg gagctctacc gcgcggcctg
     8761 cgcccacgac ctggagacgg cgctgcctct ctaccgggcc ctgcacccgc tgctgcgcca
     8821 ggactccggg accgagttcg tgcagtccat caagctctcg atggacctgg cgggccgccg
     8881 cggcgggccc acccgaccgc cgcgcctccc gctcggcgga cccgcggaag cactggtgcg
     8941 cgcggccacc gagaaggccc tggcggcagg ccaccgctga gccggccgag acccccggcg
     9001 ctcccaccga ccgacgaagg agccgtatgc gcacccgtca cgtcttccac gccgtcgatt
     9061 cgcacaccga gggcatgccc acacgcgtga tcaccggcgg cgtcggggtg atccccggcg
     9121 ccaccatggc cgaccgcagg ctgcacttca tcgagcacct ggatcacctg cgcacccttc
     9181 tgatgcacga gccgcgcggc cactccgcga tgagcggcgc gctgctccag ccgccgaccc
     9241 gccccgacgc cgactacggg gtcctctaca tcgaggtgtc cggcgtgctg cccatgtgcg
     9301 ggcacggcac catcggcgtg gccacggtcc tggtggagac cggcatggtc ccggtcaccg
     9361 agccggtcac gacggtccgc ctcgacaccc ccgccggact gatccgggtc gacgtgagcg
     9421 tcaccgacgg cgcggcgacc tcggccacgc tgaccaacgt ccccgcgttc tgcgtcgccc
     9481 tcgaccgcaa gatcgacgtg ccgggacacg gcacggtcac ctacgacctg gccttcggcg
     9541 gcaacttcta cgccttcgcg cacctcgacg ccctggggct gccgttcacc cgcgaccgca
     9601 aggacgacct gctcgcggcg ggcctcgccg tcatggcggc gatcaacgcc tcacccgacc
     9661 gcccggtcca ccccgagcag cccgacatcg ccggactcaa gcacgtctac ctgatcgcgc
     9721 ccggttcgga cgcccaccgc tcccggcacg cgatggcgat ccaccccggc tggttcgacc
     9781 gctccccctg cggcacgggc acctcggccc gcatggcaca actgcacgcc cgcggcgaac
     9841 tcccgctgga gcgcgacttc gtcaacgagt ccttcatcgg cacggagttc acggggcggc
     9901 tcatcggccg gaccgaggtg gcgggcctgc ccgcggtcgt gccacggatc accggacggg
     9961 cctggctcac cggcacggcc cagtacttcc tcgaccccga cgaccccttc ccggccggct
    10021 tcgccctctg agccgcccgc cgggccctct cccgcggccc gtccccgcgc cctgtcccgg
    10081 gccctgcccc aactgacaac gtgacattgt acgttggtgc tccgcgcggg cacgggcaca
    10141 ggcgcaggca ccacgggcgc gggcatcacc ggaggggaca ccatgggcca tctgaagcag
    10201 aagaacctga tcaccgccag ggagcggctg cgcgaccagg tcgcccacgc cttgcgcgcc
    10261 gccctgatct ccggcgagct gcgccccggc gagatctact ccgcacccgg cctcgcggag
    10321 gacttcggca tctcggcgac gcccgtgcgc gaggcgatgc tcgacctggc gcgggaaggc
    10381 ctggtcgagc cggtccgcaa caaggggttc cgcgtgaccg aggtgaacga gcgcgacctc
    10441 gaccagtaca cggagatccg cctcctgatc gaggtgccca tgatcggcag gatcacccgc
    10501 accgccgccc gcgaggacct ggaggtgctg cgcccgatcg ccgacgagat cgtacgggcc
    10561 gcccgcgagc acgacctcat cggctacctg gaggccgacc gccgcttcca cctctcgctg
    10621 ctcgccctct cgggcaacga ccgcctggtc gagacggtcg gcgacctccg caagcgctcc
    10681 cgcctctacg gcctgacgac cctcgacgcc cgcgaccagc tcaccccgtc cgccgaggag
    10741 cacggagaac tcctcgacct gatgctgacg ggcgacgcga acgcggcgga ggagtgcatg
    10801 gcgcgccacc tcggacacgt acggtcactg tgggcgcagg gcgcggcaga aggagcgtaa
    10861 aacacagaag acccctggtg aacaggggcc tcagctgagc tccagcggtc ttgccgctgg
    10921 ttgctggtgt ccgagggggg acttgaaccc ccacgcccga taaagggcac tagcacctca
    10981 agctagcgcg tctgccattc cgccacccgg accaggtgtc tgccgcctcg cggggtgttc
    11041 cccgcggcga catggacaac aataccaagg tttcggagtg cctttcacct gcgtatccgt
    11101 ccaccggcgg cgcccgggca cggaggggcc ccaggccctg cccctccgcg cccgggcgcg
    11161 cggggtcagt ccccgcagcg tccggagcgc agcgagtgca ggtgctcgct ggacttccgg
    11221 gcgaaggcga gggagtcgac cgggttgtcg tgctcggtct gccagtggtg gtagcgccgc
    11281 ccctgggggg tgcgtgccgt caccttcgac aggaacctct tgtagtcgat gtcgccgtcc
    11341 ccgacgtcgc tcatgcggta gccgtcacgg gtcgtctcgt cgcggacgcc gtccttgacg
    11401 tggaagaggg ggtagcggtg cggctgcttg agcacgtagt ccagggggtc gagacgcgcc
    11461 ggcctgccgt cggggcgctt gctgaagcgg aactgggcgc agaaggccca gtagatgtcc
    11521 atctccaggt acacgaagtc ggggtcggtc tcggcgagca gcacgtcgta gaggcggacc
    11581 ttgggcttgt ccgtggcgaa ggagaactct tcggcgtggt tgtgctggta gaacttcatg
    11641 ccgcgcttgc gggccgcctc accgtacgtg ttgaagtcct cggcggcgcg cttccacccg
    11701 tccaccgtcg agccgtagcg gaagggtccc gacgcggtcc cgatgtgctt gaggccgagc
    11761 gcctcggcgt cgtcgaggac cttgtccagg ttttgcgcga aggtgtacgc gccggggttg
    11821 ttgtcgtcgt agtagcccac gtgggacccg atggggtgca ggccgtggtc gcgggcgagc
    11881 gccttgagct gggcgagggt gatggcgccc gcggagccct gggtgtagcc ggcgaactcg
    11941 atctcgtcgt agccgtactt ctccagctcg gcgaagacgg gggcgaagcc gagggtcgag
    12001 atcttgtcgc gcaggctgta gagctggatg ccgagccgtc cgggcggcag gacggggcgg
    12061 ccccggccct tctcccccgc ggcggccggg gcggcggcgc cgccgacgag ggcggctgcg
    12121 gtggcgcccg ccgcgacacc gagcatgccg cgccggctga gtctgtgtgc gagctcgggg
    12181 tcggcggacg tcgtcttgcg gttcatgcgg ttctcctcgg ccaggtcaag ggtttgtcag
    12241 gggcgcgtca ggtcacgtcg gtggtgggtc ggggtggggt cggggtcgtg tcggggatgg
    12301 gtcggggatg ggttcgaaga acgcatcagg gatcactcgg ggccggaccc tgatggcagg
    12361 gcccggaccc tctggttcag tgggaaccag gtgacttcag cgacgcgcgg cctctcactg
    12421 caggcccgcg aggtggagca ggagcgattt cacatcggtg gccgcgacgc ggccggcgac
    12481 ggcgcggggg gtggagcaca ggatgagcgg actttcgtcc tcgttcgtgg ggaggcggcc
    12541 gtggctgccg cgaataggtg aggggtccag gggcacgacc gccatgcggt agcgcatgcc
    12601 gagtttcttg cgggccagcg cgctcgccgc cctcacgcgg acgtaggggt cctcggggtc
    12661 catgaagagt tcgacggggt cgtagccggg tttgcggtgg atctcgacga gctgcgcgaa
    12721 gtcgggcgca cggtcgtcgt cgagccagta gtagtacgtg aaccaggcgt cgggctccgc
    12781 gacggcgacg agctcgccgg cgcgggggtg gtcgagctga tgcgccttct tgccctcgtc
    12841 gtccaggagc cgctcgatgc cgggcacgtc ggcgagtgcg gcgcgggtgg cttcgaggtc
    12901 ctcggggcgg cggacgtaaa cgtgggcgat ctggtggtcg gcgacggcga aggcgcggga
    12961 ggccatcggg tcgaggtatt ccatgccgtc ctgggtgtgc acgtcgagca gcccggcgcg
    13021 gcgcagcacg cggttgatgt cgacggagcg gttcacccgc
//
