LOCUS       NZ_MRBL01000019        21935 bp    DNA     linear   CON 02-APR-2024
DEFINITION  Bacillus haynesii strain NRRL B-41327
            Bacillus_sp_NRRL_B-41327_contig_19, whole genome shotgun sequence.
ACCESSION   NZ_MRBL01000019
VERSION     NZ_MRBL01000019.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus haynesii
  ORGANISM  Bacillus haynesii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 112889)
  AUTHORS   Dunlap,C.A., Schisler,D.A., Perry,E.B., Connor,N., Cohan,F.M. and
            Rooney,A.P.
  TITLE     Bacillus swezeyi sp. nov. and Bacillus haynesii sp. nov., isolated
            from desert soil
  JOURNAL   Int J Syst Evol Microbiol 67 (8), 2720-2725 (2017)
   PUBMED   28809143
REFERENCE   2  (bases 1 to 112889)
  AUTHORS   Dunlap,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-DEC-2016) Crop Bioprotection Research Unit,
            NCAUR-ARS-USDA, 1815 N. University St, Peoria, IL 61604, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.05
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 37.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001969855.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 01:58:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,473
            CDSs (total)                      :: 4,378
            Genes (coding)                    :: 4,284
            CDSs (with protein)               :: 4,284
            Genes (RNA)                       :: 95
            rRNAs                             :: 4, 8, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1 (5S, 23S)
            partial rRNAs                     :: 8 (16S)
            tRNAs                             :: 77
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 94
            CDSs (without protein)            :: 94
            Pseudo Genes (ambiguous residues) :: 0 of 94
            Pseudo Genes (frameshifted)       :: 43 of 94
            Pseudo Genes (incomplete)         :: 64 of 94
            Pseudo Genes (internal stop)      :: 16 of 94
            Pseudo Genes (multiple problems)  :: 24 of 94
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:52:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 31174
            Orig. end                         :: 53109
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MRBL01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21935
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..21935
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21935
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11935](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11935)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(234..248)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.86"
                     /tool="antismash"
     gene            284..391
                     /locus_tag="BTA31_RS22620"
     CDS             284..391
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388844.1"
                     /locus_tag="BTA31_RS22620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YhdX family protein"
                     /protein_id="WP_003180159.1"
                     /transl_table=11
                     /translation="MGKGRIKVEERIKIETDAEMFKATLLDQTQSQKKK"
     gene            575..1651
                     /locus_tag="BTA31_RS16925"
                     /old_locus_tag="BTA31_16935"
     CDS             575..1651
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180161.1"
                     /locus_tag="BTA31_RS16925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16935"
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_076793254.1"
                     /transl_table=11
                     /translation="MFEKYMTMDFAAEIGISIGILLLFFTFRKIFTKYLFNLILKLTNK
                     TKTDFFNQVVLAFEKPARWFFAILGIYLAIIYSPFFDGHMAVVHKLYRVSVILVIVSGL
                     YNLTAASSVLFDKINKRLELDMDDILAPFLSKILRFIIVALGISVIAGEFNYDVNGFVA
                     GLGLGGFAFALAAKDTVGNFFGGIVIIMEKPFTIGDWIETNIVIGTVEDISFRSTKVRT
                     AGEALVTVPNSVLANEAIMNWTKMRKRQVTFTLEIDPSTPREKVERCVERFKEMLKTHE
                     GVNPDVIMVNFDVLKDTHLSIFFNYYTNTTVWAENLDVRQDVNYRILDIMKEEQVDFVS
                     PGHSLFELKKMKDQQGNA"
     gene            1681..2430
                     /locus_tag="BTA31_RS16930"
                     /old_locus_tag="BTA31_16940"
     CDS             1681..2430
                     /EC_number="2.3.1.286"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180163.1"
                     /locus_tag="BTA31_RS16930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16940"
                     /product="NAD-dependent protein deacylase"
                     /protein_id="WP_076793255.1"
                     /transl_table=11
                     /translation="MEEEALRFADMIENAERITVLTGAGMSTESGIPDFRSAGGIWTED
                     LSRMEAMSRDYYERYPKLFWTKFKELFQMKMTGTYQPNDGHLYLAELAKSGKDVRVFTQ
                     NIDGLHLKAGSRHVYELHGSIQTATCPKCGARYGLDHILQEEVPRCNRVNGKGRECGFI
                     LKTDVVLFGDAVQHFDTLFEALNESDLLLVIGTSLEVAPVRFVPEEAHLIPGLKKAMIN
                     LDETSYDHLFDIVIHQKIAEFVRKLNR"
     gene            complement(2474..2968)
                     /locus_tag="BTA31_RS16935"
                     /old_locus_tag="BTA31_16945"
     CDS             complement(2474..2968)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180165.1"
                     /locus_tag="BTA31_RS16935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16945"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_076793256.1"
                     /transl_table=11
                     /translation="MKIEELHSTVEYTNQLAELLIRVVDDGASVGFLPPLEKRRAVAYW
                     KKAVTPDSVLWIAKQNGRIAGSVQLHLCTKQNGRHRAEICKLMTDPAFRRQGIARSLMQ
                     KAIDRAKQEGRSLLVLDTREGDPSNFLYTLLGFAEAGRIPAYAESADGGFDASVFYYKK
                     L"
     gene            complement(3102..4013)
                     /locus_tag="BTA31_RS16940"
                     /old_locus_tag="BTA31_16950"
     CDS             complement(3102..4013)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180166.1"
                     /locus_tag="BTA31_RS16940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16950"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_076793257.1"
                     /transl_table=11
                     /translation="MRQVSKKTAPSVAYLLTKAACFFVLCLILLYVWDLSQSSAATEKR
                     ELTVSENSQMRHEGDSVPLKKATQGELLDHLSTKQQIEKRKQEKEKQKAAAEKKKEKSK
                     EKTVYLTFDDGPSAVSQRLLQILSEHDAKATFFMLEPNMKLHKEAVLNMKQQGHALGLH
                     GVTHDQKQFYKGANSPNLEMKQAQKTLKSITGVETHLIRTPYGSKPSLTEAQKKVLKKN
                     GFVYWDWNIDSLDWKYRSQKFVPEVMNQLNTLEKRQTKQPIVILMHDIPSTVQSLPLLL
                     TNLKNMGYSFATLDESMTPVHE"
     misc_feature    complement(4092..4110)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.17"
                     /tool="antismash"
     misc_feature    4154..4167
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.97"
                     /tool="antismash"
     gene            4312..5163
                     /gene="dat"
                     /locus_tag="BTA31_RS16945"
                     /old_locus_tag="BTA31_16955"
     CDS             4312..5163
                     /EC_number="2.6.1.21"
                     /GO_function="GO:0047810 - D-alanine:2-oxoglutarate
                     aminotransferase activity [Evidence IEA]"
                     /GO_process="GO:0019480 - L-alanine oxidation to pyruvate
                     via D-alanine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (42-271). E-value: 3e-46.
                     Score: 150.0. Matches aSDomain:
                     nrpspksdomains_BTA31_RS16945_Aminotran_4.1"
                     /codon_start=1
                     /gene="dat"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450756.1"
                     /locus_tag="BTA31_RS16945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16955"
                     /product="D-amino-acid transaminase"
                     /protein_id="WP_076793303.1"
                     /transl_table=11
                     /translation="MKVLLNGRLIERSECAVDIEDRGYQFGDGVYEVIRIYNGILFTLD
                     EHIARLYKSAAEIGIDLTFSEAELKSQLKEIVDINQMRDGGLYLQVTRGKAPRKHQYGA
                     GLTPQVTAYTFPIQKPEKEQQNGVSAITADDLRWLRCDIKSLNLLYNVMIKQKAHEASS
                     FEAILIRDGLVTEGTSSNVYVVKQNVIYTHPVTTLILNGITRMKVLQLCEENGLNFEEK
                     AVTKDELLNADEVFITSTTAEVIPVTSIDGQTIGSGAPGPLTKNVQTALQNSILSETAK
                     TV"
     aSDomain        4438..5124
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTA31_RS16945_Aminotran_4.1"
                     /evalue="3.00E-46"
                     /label="BTA31_RS16945_Aminotran_4.1"
                     /locus_tag="BTA31_RS16945"
                     /protein_end="271"
                     /protein_start="42"
                     /score="150.0"
                     /tool="antismash"
                     /translation="TLDEHIARLYKSAAEIGIDLTFSEAELKSQLKEIVDINQMRDGGL
                     YLQVTRGKAPRKHQYGAGLTPQVTAYTFPIQKPEKEQQNGVSAITADDLRWLRCDIKSL
                     NLLYNVMIKQKAHEASSFEAILIRDGLVTEGTSSNVYVVKQNVIYTHPVTTLILNGITR
                     MKVLQLCEENGLNFEEKAVTKDELLNADEVFITSTTAEVIPVTSIDGQTIGSGAPGPLT
                     KNVQTAL"
     gene            complement(5204..6562)
                     /gene="nhaC"
                     /locus_tag="BTA31_RS16950"
                     /old_locus_tag="BTA31_16960"
     CDS             complement(5204..6562)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nhaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328967.1"
                     /locus_tag="BTA31_RS16950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16960"
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="WP_076793258.1"
                     /transl_table=11
                     /translation="MSNEKRLSFSISALLFLAILFIIFTCLFIFKAEAHIPLLICVGFL
                     AAVGAVKGHSWKDLESGIVSGIRNGVQPIIVLCLIGILIGVWEYSGAIPTVTVYALNLI
                     EPQHLLLTALFSCLVISSLVGSSFTTVSTIGVALIGVAAAAGVPLTWAAGAVICGACFG
                     DKMSPMSDTTNFAAGVGELPIFKHIRHMAGTTVPALLITILLFFFMGRSLTAAPASTEN
                     IQAIINGIEGTVNISVWSLLSPLLVIVLAVRRTPVIPSLAAGIVSAGILAALIQPDASI
                     SSFLSAMQNGPVFSADNEAVEKILNRGGLQSMMGSVSLIIIAFALGGLMEKIGLITSLL
                     EGVIKGIHTKGRLVFSTVSSSIGMNLATGEQYLSILIPGQSFKKLYDKLGIDRKHLSRS
                     LEDGGTLINPMIPWGVSGAFMSSALGVPVIEYLPFVFFLYLSPIFSILFGFRK"
     gene            6799..7779
                     /locus_tag="BTA31_RS16955"
                     /old_locus_tag="BTA31_16965"
     CDS             6799..7779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328966.1"
                     /locus_tag="BTA31_RS16955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16965"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_076793259.1"
                     /transl_table=11
                     /translation="MSYTVQKSRFLHEEAIWFENDDLEAVLVPGWGSNLISLKWKPGGL
                     NLLKTPATKEEYDANPFLFGIPVLFPPNRIDHGRFTYAGRTYELPINEKPLENHLHGFL
                     YDKKWTVEKMEATEERIIVQTKLDSDDHPSIQAIFPHSFAITITYTLEGQHLKIDASAV
                     NRGQDPMPIGLGYHTSFRYPLNEAGDKEKCLFTLPASKQWTLTDRMLPTGEYRMTEEFK
                     AGKMAAGERLDDILAAEQDREGNSTAVISDSLAGIRVRYQCDGHFKHWVVFNGTSDQDD
                     LLCIEPYTWMTNAPNVNLPKNVSGFRDLGPQEELMMRSKIEVGGI"
     gene            complement(7795..8028)
                     /locus_tag="BTA31_RS16960"
                     /old_locus_tag="BTA31_16970"
     CDS             complement(7795..8028)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027626.4"
                     /locus_tag="BTA31_RS16960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16970"
                     /product="DUF4944 domain-containing protein"
                     /protein_id="WP_275667500.1"
                     /transl_table=11
                     /translation="MVTKFDDEILLNAQIETPMKDYAGGEFPGGGSKEQSVSFLEGLEE
                     AEFAGRKVTVQLDWREGKQASHTAFTLDKCSW"
     misc_feature    8123..8139
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.0"
                     /tool="antismash"
     gene            8198..8908
                     /locus_tag="BTA31_RS16965"
                     /old_locus_tag="BTA31_16975"
     CDS             8198..8908
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BTA31_RS16965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BTA31_16975"
                     /product="hypothetical protein"
                     /protein_id="WP_076793260.1"
                     /transl_table=11
                     /translation="MKNIFVSLLVLCLVSISAFVGIEDAFAAEELQEASYSEPIKSADD
                     LQYDVNKNLTQEEITSRFNKINTKYDVGQAFSEQDAEFIKFYSESQLGTPAELNDGISI
                     SAIQWYPGQTASKSFNTSKSSNGVKVKFSGKVYGTIGIVNHSYRGKLSAKITSGTSKVK
                     KALKVRVTHSAYGLVGKKSIGIVYNSGKSSTGTKSKVSMDNTVKYSALAVVYTYTNAYV
                     SVTTKTGSFNKYAF"
     gene            complement(9446..9931)
                     /locus_tag="BTA31_RS16970"
                     /old_locus_tag="BTA31_16980"
     CDS             complement(9446..9931)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180175.1"
                     /locus_tag="BTA31_RS16970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16980"
                     /product="YdhH/YoaO family protein"
                     /protein_id="WP_239693231.1"
                     /transl_table=11
                     /translation="MVNIKQQYKRPVLFIASLFIAFCAVYFGGRLIGLYMAEYPKWNGQ
                     SADGNWEAVIKKGDEGREFSGNLYWTGSRERLDDTYLEKLVVKFDDEIVLNAQIETPMK
                     DYAGGEFPGGGSKEQSVSFLEGLEEAEFAGRKVTVQLDWREGKQASHTAFTLDKCSW"
     gene            complement(10001..11935)
                     /locus_tag="BTA31_RS16975"
                     /old_locus_tag="BTA31_16985"
     CDS             complement(10001..11935)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180177.1"
                     /locus_tag="BTA31_RS16975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16985"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_076793261.1"
                     /sec_met_domain="TIGR03882 (E-value: 2.4e-51, bitscore:
                     167.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.1e-134, bitscore:
                     441.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 9.1e-87, bitscore: 284.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRCILVVGEGLMAEGASQQLSAEYDVIRRPDFENRIPAETSFVL
                     VLHDAWRPLLYREAEKVLRAAGIPWLRGFASFGEGVIGPLVYPSASGCSECADMRRYVS
                     GPDSRETLELEQKSNGISRDPWASKTGCRQMVNLICTEVDTIMNGGRGRLKKKLYIVNL
                     KTLECSLHAFIPEPTCPVCGSLPEDGPESARISLRPSLKTNPDSFRVRNTDDLKQTVSK
                     DYLDQRTGLFNAKIYDAILPFADMIVNMPLWMGNEGVGGRSHSYEDSELTAILEGLERY
                     SGIEPRGKRTVVHDTYENVKDRALDPAKVGLHRAEQYMHPDFPFQPFHPARPLRWVWGY
                     SFLQKRPILVPESLAYYSLGREDSFVYETSNGCALGGSLEEAIFHGILEAAERDSFLLA
                     WYARLPLRQLDLDSSGDPELRLMTERVRSVAGYDLHVFNSTMEYGIPSIWAIAKNRKQE
                     GLNLICSAGAHPDPVKAVKSALHELAGMMLKHDRKFESERSKYYQMLRSPALVREMEDH
                     SFMYGLPEAEERLRFLLNQSRPLQTFDDAFKKRKKHLDLTEDLCDLLEAFRSLNLEVIV
                     VDQTSPVIEQNGLYCVKVLIPGLIPMTFGQRFIRLEGLERIFTVPKKLGFAEEPLTQEQ
                     VNLHPHPFP"
     gene            complement(11935..13788)
                     /locus_tag="BTA31_RS16980"
                     /old_locus_tag="BTA31_16990"
     CDS             complement(11935..13788)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016886167.1"
                     /locus_tag="BTA31_RS16980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_16990"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_076793262.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1156.7,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     3.4e-53, bitscore: 170.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 8.4e-15,
                     bitscore: 47.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHLTASARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQW
                     IEKLLPMFNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRDISRDHPHKLESSVLK
                     TYEAQIEFIESFADSGAYRFQLSRQTKILAAGTGSFLTKLVQSLIDSGFSRIRAIVTDA
                     SGHTLDELAEISRRTENGLEIGFAETQHWREAVRSADWVLYVSDRGFTDELRDLQTFCL
                     EENKGFIPGICLKQVGLAGPVFHQPGDSCFEAAWRRLHRSALHEERTLETFPSAGKDML
                     ANVIVFELMKTAAELAPLSKKNQVYLIDLATLEGGWHAFLPHPDFACGKDSAELIFDLE
                     AKLSERPEREAESRLFQCFTELTSPVTGIFHLWEEKHLRQLPLAQCFVQTADPLSSGPA
                     ELLPETVSIGLTHQEARREAGLTGIEMYASRLTRSYPNNGDFAIAAGETLAEGVLRGME
                     KCLEHRLRERIKSGKETISLVQLDGMEDRHSAFYLKALTVLYGKPEIGLGKNIEGFPVA
                     WAGIRGRWYGSSGLNITSALRKALERALTDKDPLKGADVLLEPGETKLAIPVSAALQQT
                     LLSALKNNRGLQLYVYELPAEPFLKEKLAGIYCVQLRKEEP"
     aSDomain        complement(13489..13788)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BTA31_RS16980_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="8.50E-54"
                     /identifier="RREFam011.1"
                     /label="BTA31_RS16980"
                     /locus_tag="BTA31_RS16980"
                     /protein_end="100"
                     /protein_start="0"
                     /score="170.5"
                     /tool="antismash"
                     /translation="MTHLTASARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQW
                     IEKLLPMFNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRDISRDHPHKLES"
     aSDomain        complement(13522..13767)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BTA31_RS16980_Thiopeptide_F_RRE.1"
                     /evalue="2.10E-15"
                     /identifier="RREFam004.1"
                     /label="BTA31_RS16980"
                     /locus_tag="BTA31_RS16980"
                     /protein_end="89"
                     /protein_start="7"
                     /score="47.5"
                     /tool="antismash"
                     /translation="ARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQWIEKLLPM
                     FNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRD"
     misc_feature    complement(13896..13909)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.9"
                     /tool="antismash"
     misc_feature    13898..13911
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.35"
                     /tool="antismash"
     misc_feature    complement(13901..13917)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.69"
                     /tool="antismash"
     misc_feature    14372..14389
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    complement(14577..14591)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.18"
                     /tool="antismash"
     misc_feature    complement(14584..14598)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.04"
                     /tool="antismash"
     misc_feature    15078..15091
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            complement(15225..15725)
                     /locus_tag="BTA31_RS16990"
                     /old_locus_tag="BTA31_17000"
     CDS             complement(15225..15725)
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017695384.1"
                     /locus_tag="BTA31_RS16990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_17000"
                     /product="universal stress protein"
                     /protein_id="WP_043928759.1"
                     /transl_table=11
                     /translation="MFKADRIIVAFDGKEESKKALKKAIDLSKRLSSQLTVAHVHEPRQ
                     VRTDAEAERPAAGAPYLYSGFPAAPRVPHDSDLAGEPMIYEDSAEEAIAAAKIILSENQ
                     YDAEIEVLEGDTANAVLQHAENIGADLVITGTRDQNRLKKLLFGSVSDKISTKSEIPVL
                     IVK"
     gene            16244..17998
                     /locus_tag="BTA31_RS16995"
                     /old_locus_tag="BTA31_17005"
     CDS             16244..17998
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388852.1"
                     /locus_tag="BTA31_RS16995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_17005"
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="WP_076793263.1"
                     /transl_table=11
                     /translation="MFSVLWKLGWFFKASWRRYTIAVVLLIIVNVLEMFPPKLLGNAID
                     DMQAGTFSKAGMLGYIGLFLALGAVVYILSYYWMYQLFGGANLVEKILRSKLMGHLLKM
                     TPSFYEKNRTGDLMARATNDLKAISMTAGFGILTLVDSTLYMLTILLTMGFLISWKLTL
                     ASIIPLPLMAAAISIYGKKIHERFTEAQDAFGALNDQVLESVSGVRVIRAYVQEKNDVS
                     RFNSMTADVYKKNMKVALIDSLFEPTVKLLVGISYLIGLGYGAYLVFRSQLTLGELVSF
                     NVYLGMLIWPMFAIGELINVMQRGNASLDRVNETLAYEPDVRESAEPEAAEPGDIVFDG
                     VTFTYPSSASENLADISFTVLEGQTVGIVGKTGSGKTTLVKQLLRQYPKGKGTITISGV
                     PIERLPLDQLRSWIGYVPQDHVLFSKSVKDNILFGGHLAEERDLHAVISAAHLKKDIEM
                     LSDGLETMVGEKGVALSGGQKQRISIARAMIAEPHILILDDSLSAVDAKTEAAIIENIR
                     SRRKGKTTFITSHRMSAVEHADFILVMEDGRIVERGTHQELIGRKGWYFEQYEAQQLPS
                     GEEGGTVA"
     gene            17995..20013
                     /locus_tag="BTA31_RS17000"
                     /old_locus_tag="BTA31_17010"
     CDS             17995..20013
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180189.1"
                     /locus_tag="BTA31_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_17010"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_076793264.1"
                     /transl_table=11
                     /translation="MTTGKRLFQYALLYKKILIWALVMLTIAVTAELTGPMIAKKMIDD
                     HILGIEKTWYETTEKTKYTVSYKGKEYIREDRTDPPAEKLQEVHIFQVGMNYYFVGEPV
                     TFDGERTVSGGELRMTSGDRTETYKADRLSLSEVYAFYEPEIGGLISLVSIYFGLLIFS
                     IFFHYGQFYLLQMSANRIIQKMRQDVFANIQRLPIRYFDNLPAGKIVARVTNDTEAIRD
                     LYVTVLSTFVTNIIYMAGIFAALFFLDVRLAGVCLLILPLIVIWAAVYRKFASGYNHKL
                     RSINSEINAKMNESIQGMTIIQAFRRGEDTKEEFEQLNDSHFHYQNKMLKLNSLMSHNL
                     VNILRNVMFTALIWYFGGAALNAESMISIGVLYAFVDYLNRLFQPITGIVNQFAKLELA
                     RVSSERVFRLLDEPGVDVKEPSSERARGRVVFEDVSFRYHDGEDVLKNISFEAKQGETV
                     ALVGHTGSGKSSIMNVLFRFYDIEKGDVKIDGRSIYDMSRQEIRKHMGIVLQDPYLFSG
                     TIASNVSLDNADITRQQIEAALKQVGALEVLARLPKGLDEPVIEKGSTLSSGERQLISF
                     ARALAYDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFIIAHRLSTIKNADQILV
                     LEKGQIIERGNHEELMKQKGQYYQMYELQKGKGTLIG"
     gene            complement(20033..20662)
                     /locus_tag="BTA31_RS17005"
                     /old_locus_tag="BTA31_17015"
     CDS             complement(20033..20662)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328963.1"
                     /locus_tag="BTA31_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_17015"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_239693232.1"
                     /transl_table=11
                     /translation="MLKIALFGGTGRVGQAFLNFVEEDGHHHSVYALVRRTEGALIPDK
                     CCQALTGNARNQHDAESLIKDCDIVVSCLNTDGDDTLTVSIEHMINAMNVHRIKRLITI
                     GTAGILNARQNPALYRFETNESKRRSTRAAQEHARVYERLRESDLDWTIVCPTYLPDGP
                     ALKTYRFERDVLPLGGKEISTGDTAHFLFTQLESDQFVKARVGLAY"
     gene            complement(20683..20820)
                     /locus_tag="BTA31_RS23085"
     CDS             complement(20683..20820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180193.1"
                     /locus_tag="BTA31_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_165569731.1"
                     /transl_table=11
                     /translation="MQVMLSINWELIQFVGISLLNEYVSNVRPYHFCYRGAFSSGRSDV
                     "
     misc_feature    20917..20935
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.9"
                     /tool="antismash"
     misc_feature    complement(20989..21004)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            complement(20991..21194)
                     /locus_tag="BTA31_RS17010"
                     /old_locus_tag="BTA31_17020"
     CDS             complement(20991..21194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390835.1"
                     /locus_tag="BTA31_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_17020"
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_020450770.1"
                     /transl_table=11
                     /translation="MANQNSSNQLVVPGAAQAIEQMKFEIASEFGVNLGADTTSRANGS
                     VGGEITKRLVSQAQASMGGQQF"
     gene            21430..21654
                     /locus_tag="BTA31_RS17015"
                     /old_locus_tag="BTA31_17025"
     CDS             21430..21654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180197.1"
                     /locus_tag="BTA31_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BTA31_17025"
                     /product="hypothetical protein"
                     /protein_id="WP_076793266.1"
                     /transl_table=11
                     /translation="MMCPVCNGILVQTRHCPKCGGEMADAGRATDFFGPYSPYMEFDSF
                     KQTQTECVHLYTCQDCTYEETVEIKTTEA"
     misc_feature    21695..21712
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
ORIGIN
        1 aaatcagccc cgagcttcac cgctttttca aaagcggcaa acgtattttc gggggcgtaa
       61 gccgaggctc cgcgatgtgc gataatatgc aaacatgtca gctcctcttg ataaaatctt
      121 tccatcacaa ggatacccga ttttggcgat gcaagtaaat cattagactg aagcggacaa
      181 aaggcaggga gaagagatgt gcgacaaatt tcggcaaaat ggtacaaaag catcatttac
      241 taaaaattct gatattttat aatggacaaa aggaggcgag atgatgggga aagggagaat
      301 taaagtggaa gaacggatta agatcgaaac tgatgctgaa atgtttaaag cgactctcct
      361 tgatcaaaca cagtctcaga agaagaaata gcagtgttga cccgaatcac gttgtctctg
      421 gaacaataaa atatgatgat catcaggctg ccgaaggtgt tcggcggcct tttatgcgtg
      481 tcgacggata tttttggcgc acaataaagt gagaaatttt ttgctcgttt tagtataata
      541 aaagcttgat gagtgaaata agggagagaa aacaatgttc gaaaagtata tgacaatgga
      601 tttcgctgcc gaaatcggaa tcagcatcgg tatccttctt ttatttttca cgtttagaaa
      661 aatatttacg aaatacttat tcaacctgat actgaaattg acgaataaga cgaaaacgga
      721 ctttttcaat caggtggtgc tggcgtttga aaagccggct cggtggtttt ttgcgatact
      781 cggtatttat ctggccatca tttattcccc gttttttgat gggcatatgg cggtcgttca
      841 taaactgtac agagtatccg tgattttggt cattgtaagc ggcctataca acttaacggc
      901 ggcttcgtcg gttttattcg ataaaatcaa taagcggctt gagcttgata tggatgatat
      961 tcttgcgccg tttctgtcca agattcttcg ctttatcatt gtagcgcttg gaatcagtgt
     1021 catcgccgga gagtttaatt atgatgtcaa cgggtttgtt gccggactcg ggctcggcgg
     1081 attcgctttt gctcttgcgg caaaagacac cgtcggcaac tttttcggcg gaattgtcat
     1141 tattatggag aaacccttta caatcggcga ttggattgaa acgaatattg tgatcggaac
     1201 tgttgaagat atatcgttca gaagcacgaa agtccgcacg gccggagagg ctctcgttac
     1261 cgttcccaac tcggtgctgg ctaacgaagc gatcatgaac tggacgaaaa tgcggaagcg
     1321 tcaggtcacc tttacgctcg aaatcgatcc gtcaaccccg agggagaaag tcgaacggtg
     1381 tgtggagcgt tttaaagaaa tgctcaaaac gcacgaaggg gtcaaccctg atgtcattat
     1441 ggtcaatttc gatgtcctga aggatacgca tttaagcatc ttcttcaact actataccaa
     1501 tacgacggtg tgggccgaaa acttggacgt cagacaggat gtgaactacc gcattcttga
     1561 catcatgaaa gaagagcagg tcgattttgt ttctccgggt cacagccttt ttgagttgaa
     1621 gaaaatgaaa gatcagcaag gaaatgctta gataacggtt tttgaaggga gacaagccaa
     1681 atggaggaag aagccctgag atttgcggat atgatcgaaa atgccgagcg cattaccgtt
     1741 ttgacaggcg ccggtatgag cacggaatca ggcattccag attttcgttc agccggcggc
     1801 atatggacgg aagatctgtc gagaatggaa gcaatgagcc gtgattatta cgaacgatat
     1861 ccaaaattgt tttggacgaa gtttaaagag ctttttcaaa tgaaaatgac cggaacttat
     1921 cagccgaatg acgggcacct ttatttagcc gaactcgcga agagcggtaa ggatgtcagg
     1981 gtgttcacac aaaatatcga cgggctgcat cttaaagcgg gaagccgcca tgtatatgaa
     2041 ctgcacggtt cgatccaaac tgccacatgc ccaaaatgcg gggcgcgcta tggtcttgac
     2101 cacattcttc aagaagaagt gccaaggtgc aatcgcgtca atggcaaggg gagagaatgc
     2161 ggattcatat taaaaacgga tgtcgtgctg ttcggcgatg ccgttcagca tttcgacacg
     2221 ctttttgaag ccctcaacga atccgacctg cttttggtga tcggcacttc actcgaagtg
     2281 gcgcctgtca ggtttgttcc cgaagaagcg cacctgatcc ccgggttgaa gaaagccatg
     2341 atcaatctcg atgagacatc ttacgatcat ttattcgata ttgtcatcca tcaaaaaatc
     2401 gccgagtttg ttcggaaact taaccgttaa aaaaggaagg cgctccagac cggagcgcct
     2461 tttttgagct tcatcacaat tttttataat aaaaaacgga tgcatcgaat ccgccgtctg
     2521 cagattccgc gtatgcggga atgcggccgg cttcagcaaa gccgagcaaa gtgtaaagaa
     2581 agttggacgg gtctccttcc cttgtatcca gcacgagaag ggatctgcct tcctgtttcg
     2641 ctctgtcaat cgctttttgc attaacgatc tggcgatgcc ctgccgcctg aaggcgggat
     2701 ctgtcattaa cttacagatt tccgctctgt ggcggccgtt ttgttttgtg cataagtgca
     2761 attgaacact tcccgcgatc cggccgtttt gtttggcaat ccacaaaacc gagtccggtg
     2821 tgacggcttt tttccaataa gccaccgccc gccgcttttc aagcggaggc agaaagccga
     2881 ccgatgcccc gtcatcgacg acgcggatga gaagctctgc caattgattg gtatattcca
     2941 cagttgaatg caactcttca attttcattt acccacccca tgatataaag ataactgcat
     3001 cataatcaga aaactgtttt tttgacaaca agtgtgtcag atttctcatt cgagggagga
     3061 aataaaaaaa tccccttcat caggggatca gacatgggat gttattcatg aacgggtgtc
     3121 atcgactcat caagcgttgc aaatgaatac cccatgtttt ttaaatttgt cagcaataac
     3181 ggcaatgatt gaaccgttga aggaatatcg tgcatcagga tcacgatcgg ctgttttgtc
     3241 tgccgctttt ccagcgtatt cagctggttc atgacttccg gaacgaattt ttggcttctg
     3301 tatttccagt ccaggctgtc aatattccag tcccaataaa caaatccgtt ctttttcagc
     3361 acttttttct gcgcttcggt cagcgaaggt ttgcttccgt acggtgttct gatcaaatgg
     3421 gtttcgaccc cggtgataga cttcagcgtt ttttgagcct gcttcatttc cagattagga
     3481 gaattggcgc ctttataaaa ttgcttttgg tcatgggtta ccccgtgaag tccaagtgca
     3541 tggccctgct gcttcatatt gagaacggct tctttgtgaa gcttcatgtt cggttcgagc
     3601 atgaagaatg tcgctttagc atcatgttcg gataaaattt gcagcagcct ttggcttacg
     3661 gctgaaggcc catcatcaaa cgtcaaataa accgtttttt ccttcgattt ttctttcttt
     3721 ttttccgcag cagctttttg cttctctttt tcctgcttgc gcttttcgat ctgctgtttt
     3781 gtgctcaagt gatcgagaag ttcgccttgc gttgcttttt tgagcggaac gctgtctcct
     3841 tcatgcctca tttggctgtt ttccgacacc gtaagctctc ttttctcagt agcggcagag
     3901 gactgtgaaa ggtcccacac gtacaggaga atcagacaca acacgaaaaa gcacgctgct
     3961 ttcgtcaaca gataagctac agatggggca gttttttttg atacttggcg catgtcactc
     4021 tctccgtatc atttttctcg ttccaattcc attatgagat agaatgctag tctcataaaa
     4081 taatggatca caatgtctaa gtatacagga ttggaaagaa gatgaataca ggatgaaggg
     4141 aaaaatatat caaattttaa gagaaaatgt tgaatgatag ggaatgctgt ttttttgatt
     4201 cagaaggcgg aaaaaagttt ttggaaatat tgcactattt tgaagggcag ggtcgtgtta
     4261 gaatggaatg gagaaaattc agaagtcaac aaaaaacaag gggatggaga aatgaaagtt
     4321 cttttgaacg gccggctgat tgaacggagc gagtgtgcgg ttgatattga ggacagaggc
     4381 taccaatttg gagacggcgt ctatgaagtc atccgcattt acaatggaat cttgttcacg
     4441 cttgatgaac acattgcccg cttatataaa agcgcagccg aaatcggaat cgacctgact
     4501 ttttcagaag ccgaactgaa aagccagctg aaagagatcg tcgacatcaa tcagatgcgg
     4561 gacggcggac tgtatcttca agtgacaagg ggaaaagccc cgaggaagca tcaatacggg
     4621 gcagggctta cgcctcaggt gacggcttat acatttccta ttcagaagcc tgaaaaagaa
     4681 cagcaaaacg gtgtttcggc tattactgcg gacgacttgc gctggctgag atgcgacatt
     4741 aaaagcttaa atctgttgta caatgttatg atcaagcaaa aagcgcatga agcttcttca
     4801 tttgaagcca tcttaattcg cgacggtttg gtgacggaag ggacgtcctc aaatgtttat
     4861 gtcgtcaagc aaaacgttat ttacacccat cctgtgacaa cgctcatttt aaacggcatc
     4921 acgcggatga aagtgcttca gctgtgtgaa gagaacggct tgaattttga agaaaaagcg
     4981 gtgacaaagg atgaattgct gaatgcggat gaagtgttca tcacgtcaac gacagccgaa
     5041 gtcattccgg tcacatcgat tgacgggcaa acaatcggct ccggagcgcc cggaccgctc
     5101 accaaaaatg tgcagaccgc tttgcaaaac agcattttgt cagaaacagc caaaacggtt
     5161 taacaaagaa aaacgccgtt tcctccaagg aaacggcgtt tttttatttg cggaaaccga
     5221 acaagattga aaagatcggc gataaataaa ggaaaaacac aaacggcaaa tattcaatga
     5281 cgggaacgcc gagcgcgctg gacatgaacg cgccgctgac tccccaaggg atcatcggat
     5341 tgattaatgt tcccccgtct tcaagcgatc tcgacaaatg cttccggtcg attccgagct
     5401 tgtcatacag ctttttaaag gactgtccgg gaatcaagat cgataaatac tgttcacctg
     5461 tcgccaggtt catgccgatg cttgatgaaa cggttgagaa cacaagccgg cctttcgtat
     5521 gaatgccttt gattacacct tcaaggaggc ttgtaatcag gccgattttt tccatgagac
     5581 cgccgagcgc gaatgcgatg atgatcaggg aaacagagcc catcatcgat tgaaggccgc
     5641 cgcggtttaa aatcttctca acggcttcat tgtcggctga gaaaaccgga ccattctgca
     5701 tcgctgacaa aaacgatgaa atgctggcgt caggctgaat caacgcggca agaattccgg
     5761 cggaaacgat ccctgctgca agcgacggaa tgacgggcgt ccgtctgaca gcaagtacaa
     5821 tcacaagaag aggcgacaga agcgaccaga cgctgatgtt gactgtgcct tctattccgt
     5881 ttatgatcgc ttgaatgttt tcggttgaag ccggcgctgc cgttaaagaa cggcccatga
     5941 aaaagaaaag caaaatcgtg atcaaaagag cagggaccgt tgttcccgcc atatgtctga
     6001 tatgcttgaa aatcggaagc tccccgactc ctgcggcaaa attggtcgtg tcagacatcg
     6061 gagacatttt gtcgccgaag caggcgccgc aaatcacagc tcccgccgcc catgtcaggg
     6121 gtacgccggc cgccgcggcc acaccgatga gggcgacgcc gatcgtgctg accgtcgtga
     6181 agcttgagcc gactaatgaa ctgatcacaa gacagctgaa aagtgcggtg agcagcaggt
     6241 gctgcggttc aatcaggttc aacgcgtaaa ccgttaccgt tggaatcgcg ccgctgtact
     6301 cccagactcc gattaagatg ccgattaagc aaaggacaat aatcggctga acgccattcc
     6361 ggatgcctga gacaatgccg ctctcaagat ctttccaaga atggcctttc accgcgccga
     6421 ccgcggccaa aaaaccgacg caaatcaaca gtggtatgtg cgcttctgct ttaaatatga
     6481 ataagcatgt aaaaataatg aacaatatgg ccaaaaacaa tagagccgat atggaaaacg
     6541 atagtcgttt ttcgtttgac aaatcataca cctcattaga agaaatatct ctctttaata
     6601 ctttgatgct tttgtgcata aacgtattat aacagaaaaa tagatcatat acttaaatta
     6661 aaatatttca aacatttttc aaaggttcgc ccattctatt ttgaaagcgc tgactttttt
     6721 aagatataat tgattggaga aagacatgta tttgatacac gtttcaatga tcttttagct
     6781 aaaatagggg gaaatgcgat gtcttacact gttcagaaaa gccggttttt acatgaggaa
     6841 gcgatctggt ttgaaaatga tgatttagag gccgtacttg taccagggtg gggaagcaat
     6901 ttgatttcat tgaagtggaa gccgggcggg ttgaatttgt tgaaaacgcc tgcaacaaag
     6961 gaagaatatg acgcgaatcc gtttttattc ggaatccctg ttctttttcc tcccaaccgg
     7021 atcgatcacg ggagatttac atatgcggga agaacgtacg agctgccgat caatgaaaag
     7081 ccgctcgaaa atcacctgca cggatttctt tacgataaaa agtggacggt ggaaaaaatg
     7141 gaggcaacag aagagcggat catcgtgcag acgaagctgg actctgatga tcatccgagc
     7201 atccaagcaa tcttccctca ctcgtttgcc atcaccatca cctacacatt agaaggacag
     7261 catctgaaaa tcgatgcatc ggctgtcaac cgcggtcaag acccgatgcc gatcggattg
     7321 gggtatcaca catctttccg ctatccttta aacgaagcag gagataaaga aaagtgcctg
     7381 tttactcttc ctgcctcaaa gcaatggacg ctgacagacc gcatgctgcc gacaggcgaa
     7441 tatcggatga cagaggagtt caaagcgggg aaaatggcag cgggagaaag gcttgatgat
     7501 atattggcgg ctgagcaaga ccgagaagga aacagcaccg ccgtcatttc ggacagcctc
     7561 gccggcattc gcgtccgcta ccaatgcgat ggtcatttta agcactgggt cgtgtttaac
     7621 ggtacctctg atcaagatga tctgctttgt attgagccat atacttggat gacgaatgca
     7681 ccgaacgtga accttccgaa gaatgtgagc ggatttcggg atttggggcc gcaggaagag
     7741 ctgatgatgc gcagcaaaat tgaggtgggc ggaatataat cgatattcca ccttttacca
     7801 cgagcattta tcaagcgtaa atgctgtatg ggacgcttgt ttgccctctc tccaatccaa
     7861 ttgaaccgtc accttgcggc cggcgaattc ggcttcttca agcccttcca aaaaagaaac
     7921 agattgttct tttgaccctc cgccggggaa ttcgcctccc gcgtaatctt tcatcggcgt
     7981 ttcgatttgg gcgttcaaaa gaatttcatc atcaaacttt gttaccattg tttatagtca
     8041 agtaatcata tatactctca ctattagaca agtattccgg aagattatta agaaatctgt
     8101 tgattaaaat gagatggaaa tattgtaaaa acttaacatt ggtggtttct tttatgttac
     8161 aatacatatg aaaataaggg ggaaagaagg ttttttaatg aagaacattt ttgtaagtct
     8221 attggtcctt tgtctagtct ctattagtgc tttcgtcggt attgaagatg cttttgctgc
     8281 agaggaatta caagaagcgt cttattctga acctattaaa agtgcagacg atctacaata
     8341 tgatgttaat aaaaatttga ctcaggaaga aataacatct agatttaaca agataaatac
     8401 aaaatacgat gttggtcagg ctttttctga gcaggatgct gagtttataa agttttattc
     8461 ggaatctcaa ctgggaactc ctgccgagtt aaatgatggg atatcaatta gtgcaattca
     8521 atggtatcca ggtcaaacag ccagcaaatc tttcaatact tcaaaaagtt ctaatggagt
     8581 gaaagttaaa ttctctggga aagtctatgg tacaattggt attgtaaatc atagttatag
     8641 aggtaaattg agtgcaaaaa taacttctgg aacatctaaa gtaaagaaag cattgaaagt
     8701 acgggtaact cactcggctt atggattggt agggaaaaaa tcaattggca ttgtatataa
     8761 cagtggaaaa tcttctacgg gaacaaaatc caaagtttct atggataata ctgttaaata
     8821 tagtgctctt gcagttgttt atacctatac gaatgcctat gtatcagtta ctacaaaaac
     8881 aggttctttc aacaagtatg ctttctaatg atatgataga gaaggagaga ttgctttgat
     8941 caatttttca ataataaatg cggtcattgt attaggggtc ttactattaa ttgtttgggg
     9001 aattgtctcc tttattaaca ggttaagaaa atcaagaaga tcataacatg atgagaggcc
     9061 ggacatttga ccggcctctt ttaaaatagt tattttacaa tcagcagcgg aatctccgat
     9121 tttgtcgata tcttgtcgct gacgttgcct ggttattaca atgtttcaac gagctgactt
     9181 cacccgtaac gggcattttt catctgtggg gagaaaaaca tttgccgcag cttcctttag
     9241 cacaatgctt tgttcagata acagctccgc tctctgccgg acccacggag cttttccttg
     9301 agctggtttt gatacttgga tgacgaatgc accgaacctc aaccttccga agaatgtgag
     9361 cggatttcgg gatttggggc cgcaggaaga gctgatgatg cgcagcaaaa ttgaggtggg
     9421 cggaatataa tcgatattcc gccttttacc acgagcattt atcaagcgta aatgctgtat
     9481 gggacgcttg tttgccctct ctccaatcca attgaaccgt caccttgcgg ccggcgaatt
     9541 cggcttcttc aagcccttcc aaaaaagaaa cagattgttc ttttgaccct ccgccgggga
     9601 attcgcctcc cgcgtaatct ttcatcggcg tttcgatttg ggcgtttaaa acgatttcat
     9661 catcaaactt tacgaccaat ttttccaaat atgtatcatc cagccgctcc cggctgcctg
     9721 tccaatacag gttcccgctg aattcgcggc cttcatcgcc ttttttaatc acggcctccc
     9781 aatttccgtc agcgctttgc ccgttccatt tcgggtattc cgccatatac aaaccgatca
     9841 gcctgccgcc gaaataaacg gcgcaaaagg ctatgaagag ggaggcgatg aatagaaccg
     9901 gccgcttgta ttgctgtttt atattaacca ccgcctaaaa agttctgctt tatgatcata
     9961 aagcagaaca atcggaaaaa aaaagccatt ctcttaaatt ttaagggaac ggatgcgggt
    10021 gcaggttcac ctgttcttgt gttagcggtt cttctgcaaa gccgagcttc ttcggcactg
    10081 tgaaaattct ctcaagccct tccaggcgga tgaagcgctg tccgaatgtc atcggaatca
    10141 ggcccgggat gagcactttc acacaataaa gtccgttctg ttcgataaca ggggaagtct
    10201 gatcaacgac gatcacttca aggttgagac tccggaaagc ttcaagcagg tcgcagagat
    10261 cttcggttaa atcaagatgt ttctttcttt ttttaaaggc atcgtcgaat gtttgcagag
    10321 gccggctttg attcagcaaa aaccggaggc gctcttccgc ttcgggcagt ccgtacatga
    10381 agctgtgatc ctccatttcc cgcactaaag caggactgcg gagcatctgg taatatttgc
    10441 tcctttcaga ttcaaatttg cggtcgtgct tcaacatcat gcctgccagc tcatgaaggg
    10501 cgcttttcac cgcttttacg ggatcggggt gggcgcctgc ggaacaaatc agattcaatc
    10561 cttcctgttt tctgtttttg gcgatcgccc aaatgcttgg aatgccgtat tccatcgttg
    10621 aattaaagac atgcagatca tatcccgcca cacttcgcac tctctctgtc atgaggcgta
    10681 attccggatc tcctgaagag tcgagatcca gctgccgaag tggaagcctg gcataccagg
    10741 caagcaaaaa tgaatcgcgc tcagccgctt ctaatatgcc gtggaaaatc gcttcctcca
    10801 aactccctcc gagtgcacag ccgttcgatg tttcatagac aaagctgtct tcgcgcccca
    10861 ggctgtaata cgcgagcgat tcaggaacga gaatcggccg tttctgcaga aatgaatagc
    10921 cccataccca gcggagcggg cgggccgggt gaaacggctg aaaaggaaaa tcgggatgca
    10981 tgtattgttc ggcacgatgg agcccgactt ttgccgggtc gagcgcacga tcctttacat
    11041 tttcgtaggt gtcatgtacg accgtccgtt tgccgcgcgg ttcaattccg gaatagcgtt
    11101 ccaaaccttc taaaatggcg gttaattcgc tgtcttcata cgaatggctc cgccctccga
    11161 ccccttcatt tcccatccat aaaggcatat tgacgatcat atcggcaaac ggcagaatcg
    11221 cgtcataaat tttggcgttg aacagccccg ttctctggtc cagatagtct ttggagaccg
    11281 tctgttttaa atcgtccgta ttccgcacgc gaaagctgtc cggattcgtt ttcaggctgg
    11341 gccgaagcga tatccgcgcg gattccggtc cgtcttcggg cagactgccg catacagggc
    11401 atgtcggttc cgggatgaaa gcgtgcagcg aacattctaa cgttttcaaa ttgacgatgt
    11461 acagcttttt tttcaatcgg ccgcgcccgc cgttcatgat ggtgtcgact tctgtgcaga
    11521 tcaggttgac catctggcgg cagccggtct ttgaagccca cggatcgcgg cttatgccat
    11581 tgcttttttg ttccagttca agcgtctctc tgctgtcggg gccggagaca taccgcctca
    11641 tatcggcgca ttcggaacat cctgacgctg acggataaac gagcggcccg attacccctt
    11701 cgccaaaaga tgcaaacccg cgaagccacg gaatccctgc cgcccttagc accttttcgg
    11761 cctcgcgata taacaaaggc cgccatgcat cgtgcagcac aagaacgaac gaagtctccg
    11821 ccggtattct gttctcaaaa tcaggccttc ggataacgtc atattcggca gataattgtt
    11881 gtgatgcgcc ttctgccatc aatccttcgc caacgaccaa aatacagcgc ttcatcaagg
    11941 ttcctccttt cgcaattgca cgcagtagat gcctgccagt ttttctttta aaaatggttc
    12001 agcaggcagc tcatagacat acagctgcaa gccgcggttg tttttcaagg cggaaagcag
    12061 tgtttgttgc aaagcagctg aaacggggat agcaagcttc gtttcaccag gctccagcag
    12121 aacatccgcg cctttcaaag gatctttgtc tgtcagcgcc cgttcgagcg cttttctgag
    12181 agccgatgtg atgttgagtc cagaacttcc gtaccagcgg ccgcgaattc ccgcccatgc
    12241 gacagggaag ccttctatgt ttttccctaa accgatttcc ggtttgccgt acaagactgt
    12301 cagcgctttt aaataaaatg cagaatgccg gtcttccatt ccgtccagct gaacgaggga
    12361 tatcgtttct tttccgctct ttatccgttc tcgcaaccgg tgttccaagc atttctccat
    12421 tccccttaat acgccttcag ccagcgtttc tccggcggcg atcgcgaaat ccccgttatt
    12481 cggataagaa cgggtcaacc ttgatgcata catttcaata cccgtcagcc cggcttcccg
    12541 ccgcgcctct tgatgggtca aaccgatcga aaccgtctca ggcaaaagct ccgcaggtcc
    12601 ggaagagagc ggatctgctg tctgaacaaa gcattgtgct aaaggaagct gccgcaaatg
    12661 tttttcttcc cacagatgaa aaatgcccgt cacgggtgag gtcagttcgg tgaaacattg
    12721 gaataaccgg ctttctgctt ctctttcggg gcgctccgaa agtttcgctt caaggtcaaa
    12781 gatgagttca gccgaatcct tgccgcaagc gaagtccgga tgcggaagaa acgcatgcca
    12841 gccgccttcg agcgttgcca aatcaatcag gtacacttga ttcttcttag ataatggcgc
    12901 aagctccgca gctgttttca tcaattcgaa cacaataacg tttgccagca tgtcttttcc
    12961 tgccgaaggg aaggtttcaa gcgtccgttc ttcatggagc gcagaccgat ggaggcgcct
    13021 ccaggcagcc tcgaagcagc tgtctccggg ttgatggaag acagggcctg ccagtccgac
    13081 ttgtttcaga cagatgccgg gtatgaagcc tttgttctct tcgaggcaaa acgtttgaag
    13141 atcgcggagc tcatctgtga agccgcggtc agagacatac aaaacccaat cggcagatcg
    13201 gaccgcttcc cgccaatgtt gcgtttcggc gaagccaatc tccagtccgt tttctgttcg
    13261 ccttgatatt tctgccagtt cgtctaaagt gtgcccggat gcatccgtca cgatcgcacg
    13321 gattcttgaa aaaccggaat cgatcagcga ctggaccaat ttcgtgagaa aggagccggt
    13381 ccctgcagcc aatattttcg tttggcgcga cagctgaaat cggtaagcgc cggaatcggc
    13441 aaagctctca ataaattcga tttgggcttc atacgtttta agcactgagc tttccagttt
    13501 gtgcgggtga tcccggctta tgtcgcgaac gaacccgttt ttataaagca tttctccgat
    13561 ttcatatact ctctttcggt acggagcttg cagccctttt gtcaaatctt caagcgaatg
    13621 ttccccgttg aacatcggca gaagtttttc gatccattga gcaatcgatg atccttttat
    13681 gcgaaacgac ccggaattat ttctaaaata tgcgccgccg ttcggatcag gaagaaacca
    13741 tgtatcctgg tttactttca ggcgagcgga agcagtcagg tgtgtcatgc tcctcctcct
    13801 ttcatgtatt aaaaacaaga cataccatta tatgtaattt tgttcgtcct ttatgctata
    13861 aaagaccccc tgcggcaaaa gaggcagggg aagtcttctt ttataaaaaa actacatgcc
    13921 tccgtgccaa cagctccagc agcaatggcc cgcacagctc cagcagctgt gacccgcgca
    13981 gctccagcag ctgtgacccg cgcagctcca gcaactgtgg cccgcgcagc tccagcaact
    14041 gtggcccgca cagctccaac agctgtggcc cgcgcagctc caacagctgt ggcccatgca
    14101 gctccaacag ctggcacagc ttccgcagct ccagcagctt gcgcagtgtt taatattggc
    14161 gtgatggcgg ttcgcatccc aatgcgtcat atcgtctgcc tggaactgat ccatctccaa
    14221 cgactgcagt tcatcatgga attgttgcat tttaatatcc tccttcatcg gtaaaatgtt
    14281 aacgatcaaa aacagcaaaa gaagaatgaa acataggcaa agtcagatta agtcaaatac
    14341 cccgggtact cacaagatca aattatgagg tctgttaggt ggttgttact gatttgaacg
    14401 cctatttttc ctgttattgg atttcgttga agaggggctt ttattttgca taaagatcgt
    14461 tggaggccgg gagaggatga caataagtaa aaccaaggaa tgcggggcaa aatggagaaa
    14521 gaaaatcaat tgtaagttat gtagcatcaa agaatgcagt ctatgaaaat aaggagagaa
    14581 aaagattttc agaaaagttt ttgttagctt ataggtcctt tgtttagtct cgtcagtgca
    14641 atggttggta tctatggaaa ttttgctgtc gatttcgatc tgaaaataag atattaataa
    14701 aaatttgact aaaaagaaat agcttcaatt gaataaaaat ttaatgcgga ttctcatttg
    14761 agaactcagt gaaggaaaat tccaatggag tgatagtcga attctcaggg gacagtcgta
    14821 aattgaatgc aaaaataact tctggaaaca tctaaagtaa agaaagcata gaaagtaggt
    14881 aaccattcag cttacggatt agcaggaaaa aattcaattg gcgttgtata tagcagtgga
    14941 gcaacttcta agggcacagt gctcttgtag ttttatgctg atgcgaatgc ttatgtatca
    15001 gttactacaa caaacgggtt ctttcaataa gtatgctttc tcatgatatg atagagaagg
    15061 agagattgct ttggtcaatt tttcaataat aaatgcggtc attgttttag gagtcttact
    15121 attcattgtt tgggggattg tctcctttat taacaggttt agaaaaacaa gaaaatcata
    15181 acatgatgag aggccggaca cttgaccggc ctcttttaaa atcgttattt cacaatcagc
    15241 accgggatct ccgattttgt cgatatcttg tcgctgacgc tgccaaacag gagctttttc
    15301 aggcggttct ggtcgcgcgt acccgtgatg acgaggtcag cgccgatgtt ttccgcatgt
    15361 tgcagaactg cgttggccgt gtctccttcc aacacctcaa tttccgcgtc gtactggttt
    15421 tcgcttaaaa tgattttcgc tgccgcaatc gcttcttccg cgctgtcctc gtagatcatg
    15481 ggttcaccgg ccaaatctga atcgtggggg acccggggcg cggccgggaa gccgctgtaa
    15541 aggtatggcg cgccggcagc gggtctttcg gcctcagcgt ctgttctcac ttgtctcggt
    15601 tcatggacat gggcgacggt caattgtgag ctgagtcttt tcgataggtc gatcgctttt
    15661 ttcagcgctt ttttgctttc ctcttttccg tcaaacgcga ctatgatccg gtcagcttta
    15721 aacaaattga tcattccttt cagaatggat ttactgttat attacccgtt ttcccaacaa
    15781 atctaacgaa atatgagaat atgaatcaaa agactgccat tcgtcaaaaa aacaaattga
    15841 caattaaagg gccgtactat aagatggaaa atattaataa gattggaggg tatcgtcatg
    15901 attagaaata tcaatgcatc agttcaacaa caaaagcacc taaacgtgac atttccatac
    15961 cttccttatg atcggaaaac cgtttcactc taacaccttc aaaggagggc gcatgtcgcg
    16021 tgaacaagcg tacatgcgcc ttttttatat tggaaaaggc atgctggtac acagtgtgcc
    16081 tttttttctg agaaaaaaca ttctgttccc gatgcggagc agcatgtttt tctaataaat
    16141 caaccgcaca taaggaggaa ttttttatgc cgagtatcag aaaaaacgaa atcaaagatt
    16201 gtaaggaaaa acttgaaggc ggctaaaaag gagaggatat cagatgtttt cagttttatg
    16261 gaagctgggc tggtttttta aagcctcttg gcggcgctac acgatagcgg tcgtcctgtt
    16321 gattattgta aacgtattgg aaatgtttcc gccgaagctg ctcggcaacg cgattgacga
    16381 catgcaggcg ggcacttttt ccaaggccgg catgctcggc tatatcggtt tatttctcgc
    16441 gcttggcgca gttgtttata tcttatccta ttattggatg tatcagctgt ttgggggagc
    16501 gaacctggtc gaaaaaattc tcagatccaa gctgatgggc catttgctga aaatgacgcc
    16561 gtctttttac gagaagaacc gcacagggga tttgatggca agggcgacaa atgatttaaa
    16621 agcgatttcc atgacggccg gcttcggcat tttgaccctg gtcgattcga cgctgtatat
    16681 gctgacgatc cttttaacga tgggtttttt gatcagctgg aagctgacgc ttgcttcgat
    16741 cattccgctt ccgctgatgg cggctgccat cagcatctac gggaaaaaaa ttcatgagcg
    16801 ttttacggaa gcgcaggatg cgtttggcgc tttaaatgat caagtgctcg agtccgtgtc
    16861 aggggtaagg gtgatccggg cctatgtaca ggagaaaaac gatgtcagcc ggttcaacag
    16921 catgacggct gatgtgtaca agaaaaatat gaaagtcgct ttgatcgatt cgctgtttga
    16981 accgacggtg aagcttttgg tcgggatcag ctatttaatc ggtcttggct acggcgccta
    17041 tcttgttttc cgcagccagc tgacattggg tgaactcgtc tctttcaacg tgtacctcgg
    17101 catgctgatc tggccgatgt ttgcgatcgg agagctgatc aatgtcatgc agaggggaaa
    17161 cgcttcactt gacagagtaa atgaaacatt ggcatatgag cctgatgtga gagagtccgc
    17221 tgaacccgaa gcagcggagc cgggtgatat tgtgtttgac ggggtcactt ttacgtatcc
    17281 gagctctgcg tcggaaaacc tggccgatat ttcatttact gtattagaag gacagacggt
    17341 cggaattgtc gggaagacgg gaagcggcaa aacgacatta gtcaagcagc tgttgaggca
    17401 gtatccgaaa ggaaaaggaa cgatcaccat ttcgggcgtg ccgattgagc gcctgccgct
    17461 tgaccagctt cgcagttgga tcgggtatgt gccacaggat cacgtgctgt tttcaaaatc
    17521 agtgaaagac aatattttgt tcggcggaca tctcgccgaa gaacgcgatt tgcacgccgt
    17581 catctctgca gcacatctga aaaaggatat tgagatgctt tcagacggct tggagacaat
    17641 ggtcggagag aagggagtcg ctttatccgg gggacagaaa cagcggattt caattgcgag
    17701 agcgatgatt gcggagcccc atattttgat cttggatgat tcgctgtccg ctgtcgatgc
    17761 gaaaacagaa gcggcgatta ttgaaaacat ccgcagcaga cggaaaggca aaacgacgtt
    17821 tattacatca caccggatgt cggctgtcga acacgccgat ttcattctcg tcatggagga
    17881 tggaaggatc gttgagagag ggacgcatca ggaactgatc ggccggaaag gctggtattt
    17941 tgaacaatat gaagcacagc agcttccttc gggagaagaa ggggggactg tagcatgaca
    18001 acaggaaaaa ggcttttcca atatgcgctt ctttataaaa aaattctcat ctgggcgctt
    18061 gtgatgctga cgatcgccgt cactgccgag ctgacggggc cgatgatcgc caaaaagatg
    18121 atcgacgatc atattctcgg aatcgaaaaa acgtggtatg aaacgacaga gaaaacgaaa
    18181 tatactgttt cctacaaagg aaaggaatat atcagggaag acaggacaga ccctccagct
    18241 gaaaagctgc aggaagttca catctttcaa gtcggtatga actactactt tgtaggggaa
    18301 ccggttacct ttgacgggga gcggacggtt tccgggggag agctgagaat gacgagcgga
    18361 gaccggacgg aaacctacaa ggccgatcgc ctgtctttgt ccgaagtgta tgctttttac
    18421 gagcctgaaa taggagggct gatctcgctc gtttctattt atttcggcct tctcattttc
    18481 tcgatctttt tccattatgg ccaattctac ctcttgcaga tgagtgcaaa ccgcatcatt
    18541 caaaagatga gacaggatgt attcgccaac attcaaaggc ttcctattcg ctattttgat
    18601 aatttgcccg caggaaaaat cgttgcaagg gtgacgaatg ataccgaagc gatccgcgac
    18661 ctgtatgtga ccgttctttc gacgtttgtc acaaatatca tttatatggc cggaatattc
    18721 gccgcgctgt ttttccttga tgtcaggctg gccggcgtct gtctgttgat tttgcctctg
    18781 attgtcattt gggcggccgt ttatcgaaaa ttcgcttcag gctacaatca taaactcagg
    18841 tcaatcaaca gcgagatcaa cgccaaaatg aatgaatcga ttcaagggat gacgattatt
    18901 caggcatttc ggcgcggaga ggacacaaaa gaagaatttg aacagctgaa cgacagccac
    18961 tttcattacc aaaataaaat gctgaaattg aattcgctca tgtcccacaa cttggtcaac
    19021 attctgagaa atgttatgtt caccgcttta atctggtatt tcgggggagc tgccctgaac
    19081 gcggaaagca tgatttcaat cggcgtcctc tatgcattcg tcgattactt gaatcgatta
    19141 tttcagccga ttacgggcat cgtcaaccag tttgccaagc ttgaattggc gcgcgtatca
    19201 tcggagcggg ttttccgcct gctggatgag ccgggcgtcg atgtcaaaga gccgagcagc
    19261 gaaagagcgc gggggcgagt cgtgtttgag gatgtatcat ttcgctatca tgacggtgaa
    19321 gatgtgctga aaaacatctc atttgaagcg aagcaagggg agaccgttgc attggtcggc
    19381 catacaggct caggcaaaag ctccattatg aatgtacttt tccgctttta cgatattgaa
    19441 aagggcgatg tcaaaatcga cggcagaagc atatatgata tgtcaaggca ggaaatcaga
    19501 aagcatatgg gcatcgttct ccaggatcct tacttatttt ccggcacgat tgcttcaaat
    19561 gtcagccttg acaatgctga tattactaga cagcaaatag aagccgcctt gaaacaggtc
    19621 ggggctcttg aggtgctggc ccgcctgccg aaaggccttg atgagccggt cattgaaaaa
    19681 ggaagcaccc tttcttcagg ggaaaggcag ctgatctcgt ttgcgcgtgc gctggcatac
    19741 gatccggcta ttcttatttt agacgaggcg acggcccata tcgataccga aacagaagcg
    19801 gtcattcaaa aagcgcttga cgtcgtcaaa caagggcgca ccacctttat catcgcccac
    19861 aggctgtcaa ccatcaaaaa cgccgaccag attctcgttc ttgaaaaagg ccaaattatc
    19921 gagaggggaa atcatgaaga gctgatgaag caaaaaggcc agtactatca aatgtatgaa
    19981 ctgcaaaagg ggaaaggaac tctgataggg taagccggat cttcacccgg ccttaataag
    20041 cgagccccac ccttgccttg acaaactggt cagactcaag ctgtgtgaaa agaaaatgag
    20101 cggtgtcgcc ggtggatatt tcttttccgc cgagcggcag aacatcccgt tcaaaacggt
    20161 atgtcttcaa tgccggaccg tcggggagat acgtcgggca gacgatcgtc caatccaaat
    20221 cagattcgcg gagccgttcg tacacacggg catgttcttg cgctgcacgt gtagagcgcc
    20281 gttttgattc gtttgtttca aagcggtaaa gggccgggtt ctgcctggcg tttaaaatgc
    20341 cggcggttcc aatggtaatc aaccgtttga ttcgatgtac gttcatagcg tttatcatat
    20401 gttcgatgga gacggtcaat gtatcgtctc catctgtgtt taaacagctg acaacgatat
    20461 cgcaatcttt tattaaagac tcggcgtcat gctggttcct ggcgttccct gtaagtgctt
    20521 ggcagcactt atccggaata agggcgcctt ccgtcctccg gacaagagcg taaacggaat
    20581 gatgatgccc atcctcttca acaaaattga gaaaggcctg tccgacacgg cctgtacctc
    20641 caaaaagcgc aatcttcaac atgatcactc ccatcggatc tatcatacgt cagatcgtcc
    20701 ggaagaaaaa gccccgcgat aacaaaaatg ataagggcgc acatttgaaa catactcatt
    20761 caatagagaa atcccgacaa attgaatcaa ttcccaattg atgctcaaca tcacctgcat
    20821 gccgactcct cctttatacc agcatatgaa aaaaggagaa gcgggtgcgg gctttcacaa
    20881 gatatgccgg aggtgcgggc cgacgcactg gcaatgaatg tgaaagttta tcaacacgct
    20941 aaagaaggtg caatatatgc accttctgtt atccatgaat atgaagttgt ttaaaattgt
    21001 tgaccgccca tagatgcttg agcttgggaa actaaacgtt ttgtaatttc tccgccgaca
    21061 gaaccgtttg cacgggaagt cgtgtcagcg ccaaggttta cgccgaactc agaagcgatt
    21121 tcaaatttca tttgttcgat cgcttgtgct gctcctggga caaccagttg atttgaagaa
    21181 ttttgattag ccatttgtca tcaaactcct ttataaaaat ggtatggttg ggctgactgg
    21241 agttgcacca gctgacggct ttcaccgaaa gaaaaccgct gccttctcgg ctaaagccca
    21301 atgttagttt gtactacgta ttatggtgga ttcgataaaa taaatgcgtg tttcaatctg
    21361 gtaaatgttg aaaggcgaaa aggttaggat tggggcaagc taaggaaaaa agccaggagg
    21421 atgaagaaga tgatgtgccc agtatgcaat ggcattctcg tccagacaag gcattgtccg
    21481 aagtgcggcg gggaaatggc ggacgccggg agagcaaccg attttttcgg tccctacagt
    21541 ccgtatatgg agttcgattc atttaaacaa acgcaaaccg aatgcgttca tttatatact
    21601 tgccaggact gtacttatga agaaaccgtt gaaattaaaa cgaccgaagc atagtcgtag
    21661 catgcttcgg tcatggaagt gtttgaatct ggattatcct tcagagcgga tgcgaagctc
    21721 cgtttctttg tcaaagaagt gagctttatt catgtcaagc gccaatggaa ttgtatcgcc
    21781 ggcctggacg tcggtccttg aatcgactct ggcgatgaac ggctgagtgc cggcttgcga
    21841 ataaagcatc gtttccgcgc ccatcagctc ggctacctca attttcgcat caattttcga
    21901 gtcttttgac gcatcaatga aaaccggttc atcat
//
