LOCUS       NZ_LIYH01000008        22486 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold8, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000008
VERSION     NZ_LIYH01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 410412)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410412)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6542
            Orig. end                         :: 29028
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22486
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="thioamitides"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..22486
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22486
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12486](+)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12486
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     gene            complement(<329..655)
                     /locus_tag="AMK26_RS30790"
                     /old_locus_tag="AMK26_30315"
                     /pseudo=""
     CDS             complement(<329..655)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012492354.1"
                     /locus_tag="AMK26_RS30790"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30315"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPQPWLIDDELWSRIEPLLPVRQSRHRHPGRKALDDRKVLCGILF
                     VLYTGIRWEWLPAELGFGSGMTCWRRLRDWNNAGVWQRLHEVLLAELRAADRLDLSRAV
                     IDSPT"
     gene            complement(665..1450)
                     /locus_tag="AMK26_RS30795"
                     /old_locus_tag="AMK26_30320"
     CDS             complement(665..1450)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS30795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_30320"
                     /product="hypothetical protein"
                     /protein_id="WP_158071160.1"
                     /transl_table=11
                     /translation="MLNLGGRIAVLDSIDAKPTIVAARKTRLLGPAAAWFPAADNDKTW
                     AVTEEPAATACSGKKLPPSVQARFTITEHDTSGSPSRTKLSLPCGMEPVAQTPQGLLVH
                     RTTEDTAGTGNGKIALTDIVLLDKQAQSVTQVIAKYATVLSTAGTRVVRKQNDCKSSAC
                     VNVYSIDDKKSKAAPRCEAGDAAGRGAIDASGRWYATAVGSGEAYQVAVLDLEANKCQE
                     ADTYPAAAGSQIDLKGALRAPNGMRLERVLQLGDSVAWV"
     gene            complement(1751..2287)
                     /locus_tag="AMK26_RS30800"
                     /old_locus_tag="AMK26_30325"
     CDS             complement(1751..2287)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044105.1"
                     /locus_tag="AMK26_RS30800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30325"
                     /product="hypothetical protein"
                     /protein_id="WP_073758725.1"
                     /transl_table=11
                     /translation="MSSPCDPQHAPTGDVSAALMMIDSRLQAVYEGKTATDPEHQALID
                     QFAASLGPRGVDEVLDGACTLIFMFMKWLRMAYEDHDEDVIACVVPNLVATMRMMPKSV
                     PSETIPTMAGLLVAAGTGLSPNLWRKQYGYWTDDEMTPLEATVFLLAEHINRLTDDPNF
                     ATRLISEALSAADAD"
     misc_feature    complement(3080..3095)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.24"
                     /tool="antismash"
     gene            complement(3149..4522)
                     /locus_tag="AMK26_RS30805"
                     /old_locus_tag="AMK26_30330"
     CDS             complement(3149..4522)
                     /EC_number="3.2.1.4"
                     /GO_function="GO:0008810 - cellulase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030247 - polysaccharide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971507.1"
                     /locus_tag="AMK26_RS30805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30330"
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="WP_073758727.1"
                     /transl_table=11
                     /translation="MKRVLALLATCATVLGLTALTGPQAAAATGCKVDYTITNQWQGGF
                     QAGVKITNLGAPVNGWTLKFTMPDAGQKIVQGWNATWSQSGSTVTAVGVDWNRTLATGA
                     ATDLGFTGSFTAANPKPTAFTLNGVTCTGSVEEEPPPTPGNGTPVDINGQLHVCGVNLC
                     NQYNRPIQLRGMSTHGIQWFNKCYNAASLDALATNWKSDLLRIAMYVQESGYETDPAGF
                     TSRVNNLVDMAEARGMYAMIDFHTLTPGDPNYNLDRAKTFFASVAARNAAKKNVIYEIA
                     NEPNGVSWAAIKSYAEQVIPVIRAADPDAVVIVGTRGWSSLGVSDGSNESEVVNNPVNA
                     TNIMYAFHFYAASHKDNYRATVSRAASQLPLFVTEFGTVTYTGGGAVDRASTTAWLDLL
                     DQLKIGYANWTYSDANEGSAAFKPGTCNGTDYSSSGVLTESGALLKSRISTPDTFPTS"
     misc_feature    complement(4502..4504)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4557..4571)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    4558..4572
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    complement(4612..4627)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.0"
                     /tool="antismash"
     misc_feature    5474..5490
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.62"
                     /tool="antismash"
     gene            complement(5791..6522)
                     /locus_tag="AMK26_RS30815"
                     /old_locus_tag="AMK26_30335"
     CDS             complement(5791..6522)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891630.1"
                     /locus_tag="AMK26_RS30815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30335"
                     /product="restriction endonuclease"
                     /protein_id="WP_073758729.1"
                     /transl_table=11
                     /translation="MSTRPRKGRVPATRRPPARGRTRRPGKRRQRADDRLIGLLVAVGL
                     AVGLVVALVNWLLAHWWVLIVPGTLAGLAGGGRLYQKQQRARWEAVRAQGLRYGLSQLD
                     ALHHTRFEDAVRDLMRRDGCTDAARVGGGGDLGADVKATDPYGRRWVIQCKHRRNGLAG
                     SPVGTPHLQVLNGTARQVHGADVAVIVTNGRVTAPAVVFAKQQRLHVVDRHTLGVWASG
                     SRPLWELLRAVPPPRKPTALS"
     gene            complement(6519..6728)
                     /locus_tag="AMK26_RS30820"
                     /old_locus_tag="AMK26_30340"
     CDS             complement(6519..6728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670252.1"
                     /locus_tag="AMK26_RS30820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30340"
                     /product="hypothetical protein"
                     /protein_id="WP_073758731.1"
                     /transl_table=11
                     /translation="MLTINVAVLLAVIVVLRLRRRTEARSRVDEKLTVVIVLALGVLIA
                     PTGVGEGIANILGQLATGVTQASR"
     misc_feature    7072..7087
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.74"
                     /tool="antismash"
     gene            7227..>7376
                     /locus_tag="AMK26_RS38145"
                     /pseudo=""
     CDS             7227..>7376
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381042.1"
                     /locus_tag="AMK26_RS38145"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIDYDSEARDYDTSRGGEPRAQASADALEQLLPQGPCTILDIACG
                     TGIVT"
     gene            complement(7714..7989)
                     /locus_tag="AMK26_RS30830"
                     /old_locus_tag="AMK26_30350"
     CDS             complement(7714..7989)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS30830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_30350"
                     /product="hypothetical protein"
                     /protein_id="WP_143608669.1"
                     /transl_table=11
                     /translation="MRMRNVLAGSAALGSALVLGGLAAPAQAAPAPVDSNTTAAAPISI
                     SAIVRVGWYSSLARCEADGANSAYSYWYCAWSSSRGAWGLYVDTDS"
     gene            complement(8150..8833)
                     /locus_tag="AMK26_RS30835"
                     /old_locus_tag="AMK26_30355"
     CDS             complement(8150..8833)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="AMK26_RS30835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30355"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_241838136.1"
                     /transl_table=11
                     /translation="MVLDSRRPFHGDVHAHPDSWSHVTVQCPRGLLPLPEKTVQHLVAV
                     PISGHRGMGAVFGRWLADIGARATEFTAADILILASVTVDLLASVIARCLEAEAALSPE
                     ARRTALRARISAFVEERLADPAMTPQMIADAHHISLRHLQQMFAEDDTSPAAWIRHRRL
                     ERCRLDLTNPHLHAHPVQAIAARWGFTDPAHFSRLFRATYAIPPRDYRNLTLEVCAHRQ
                     QPCAE"
     misc_feature    complement(9424..9439)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    9575..9585
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    9685..9705
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(9697..9710)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.72"
                     /tool="antismash"
     gene            10001..11188
                     /locus_tag="AMK26_RS30845"
                     /old_locus_tag="AMK26_30360"
     CDS             10001..11188
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR00702.1"
                     /locus_tag="AMK26_RS30845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30360"
                     /product="YcaO-like family protein"
                     /protein_id="WP_073758737.1"
                     /sec_met_domain="YcaO (E-value: 1.1e-60, bitscore: 200.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAISDQGTPAPAKGYLRGTHRVVPPEDTWQRIRPQLARYGVTRV
                     ADVTGLDDIGIPVFQAVRPASRTVSLSQGKGLTPAAARVSATMEAIELWHAENPPPASR
                     TSTARALDLPYELTALDLAEGSLLHADLPLPWLAGEGLLSGQPTLVPEPAVRLDHTYRA
                     EWAPPLFRTTSNGLASGNTLAEATAHALAELCERDALARLRARPRSDWHRLDLGSVRDT
                     DCRFLLEQYATAQVSVDVVVAERDPACFEVRIRSEAHPVTYTGAGCHLDPAIALTRALT
                     EAAQSRLTAIAGARDDLPPVLYRTAGDRPLVREDLGTRTTPWWDAPAGGDFDADIRALA
                     GSIAARTGTEPIRVVLPSPTGIPVVKVIAPGLDFDDRTNVSSGAGRYRSPDGDAR"
     misc_feature    complement(10002..10017)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.15"
                     /tool="antismash"
     gene            11185..12486
                     /locus_tag="AMK26_RS30850"
     CDS             11185..12486
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF019429.4"
                     /locus_tag="AMK26_RS30850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TfuA-like protein"
                     /protein_id="WP_073758739.1"
                     /sec_met_domain="TfuA (E-value: 8.4e-40, bitscore: 129.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTHVYAGPSLDAEAVRVLLPDAVVHPPVRHGDLTAGPAGAGDR
                     VVILDGQFFQSASVRHKEICEVIARGAAVYGAASMGALRAAELGPYGMRGSGVVHRLYA
                     TGLIERDDEVALVHTDVGDGSRPLTVALVSVRVALRRMVRSRVIGADDEARLLTAADHF
                     PFTARTWRGILHQADGVTRAIAEAVREIVDGPQHTWDIKTQDARALLSRLARTPVPPPP
                     ATTAARVPTTVHMENWRRAADSDRLALLTAAQIYADDYPRLHHRTVLQLLTGKRDEDIH
                     LLERYAADLARQRGLLSATGLRHWIGTEEAAGTDERTIARALVRSYRWSCGSAPLPALA
                     DAVRATPGTARLYELIAEVDRLNAQLTDRGYPLRRVSRAALHRHCCRHWNTAALLPALY
                     DRGFTGVADLEDRAVRFAPHLGLAEPPRLRLLDR"
     gene            12513..13460
                     /locus_tag="AMK26_RS30855"
                     /old_locus_tag="AMK26_30370"
     CDS             12513..13460
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.4"
                     /locus_tag="AMK26_RS30855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30370"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_073758741.1"
                     /transl_table=11
                     /translation="MVLDRLVSDTAELRRAWESTPLHSRGLGDFDDVFGLALAEDLIVG
                     RGLRIPYLRLLRDGGYVPASRFTHRTGTGAGQADGVADPHAVLREMERGATVVLRGMVR
                     YCPEVASFCERLSAELGLSTSAGAYLTPPHSRGAGPHYDPMSVLVRQVHGVKHWRLQAP
                     PVQWPRTLPEPGKHYDTPVIAELDLRPGESLYIPRGVVHDAWTTDSASVHITFSGDTPP
                     MWADVLHDLVDQAAAITPALRETFPWRFADAPDTVSTRAKECFAALRAFLDTVDTDALA
                     TRIIDRHAALPDPAPRGRLAAALAGTPLSQEPPR"
     misc_feature    12520..12535
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            13457..14707
                     /locus_tag="AMK26_RS30860"
                     /old_locus_tag="AMK26_30375"
     CDS             13457..14707
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="AMK26_RS30860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30375"
                     /product="MFS transporter"
                     /protein_id="WP_073758743.1"
                     /transl_table=11
                     /translation="MTSTATRDTRFPRLLAAATLSNLGDGVRVVALPLLAAATTRDPFA
                     VSALTACAFLPWFLFGLPIGALVDRSRPETFMAWANTARTVILAGLSLALLADVRSMPL
                     LYVLAFLLGIGEAAYDNAAQSLVPRIVADEKLEKTNSALITAERVGQDLAGPALGGLLF
                     AASPVLPFGLNAAAMALGVLLLTRIRTFPPPSPPRGPVVRTVVTDAAAGMRWLWRAPLI
                     RTIVLTGSALTFFTMAWEATLVLLARGPMGVSETGYGIMLAIGAIGGVAGSLLTPALVR
                     RFERRPLQIAAIAVTAALDLALAIHPHPALAALAWGGTGAAFAVWNVLSVTLRQRLVPA
                     ELLGRVNSANRTFSMAAVPLGALTGGFVADTLGLRAPLWLAAAALTVLAFAYAVATRNS
                     VVSKPNPGPDDKAGEPR"
     gene            complement(15053..15460)
                     /locus_tag="AMK26_RS30865"
                     /old_locus_tag="AMK26_30380"
     CDS             complement(15053..15460)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.4"
                     /locus_tag="AMK26_RS30865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30380"
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="WP_073758745.1"
                     /transl_table=11
                     /translation="MSSSPSTSHRRIARGAASLLFAGAIAAGASMATAPSASAAIIPNR
                     CEYTSSEPTLSYAPNTYKLAVKQVQCELNWSLYNTTLTVDGYFGSDTRAAVRKLQDCSN
                     ITIDGVVGPNTWSKLNSWARSNSWADLSGNC"
     misc_feature    complement(15448..15463)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            complement(16301..17197)
                     /locus_tag="AMK26_RS30870"
                     /old_locus_tag="AMK26_30385"
     CDS             complement(16301..17197)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (40-281). E-value:
                     9.7e-32. Score: 102.4. Matches aSDomain:
                     nrpspksdomains_AMK26_RS30870_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513540.1"
                     /locus_tag="AMK26_RS30870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30385"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_073758747.1"
                     /sec_met_domain="PF00561 (E-value: 3.7e-19, bitscore: 63.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.6e-13, bitscore:
                     44.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPAALPRIPVPARSTHRFVEVAGVEVFYRESLPERADAPVLLL
                     LHGFPSASHQFRRLIDTLGRHYRLIAPDYPGFGHTRTLDGFTYSFERLTDIVEGFTEQL
                     GLTRYAMYLFDFGAPVGFRLALRHPERVTGLVVQNGNAYAEGLSDAARDFTALTPDTPG
                     AEQTILGLFTLAATRAQYEGGTADPTLVAPEGWLLDQYFLDQPGRKRAQLALAYDYKSN
                     IAAYPDWQAWLREHRPPTLITWGTGDPFFPEPGARAYLRDVPEAELHLFPTGHFALEDH
                     LPDIAPLVAGFLNCLPT"
     aSDomain        complement(16355..17077)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS30870_Abhydrolase_1.1"
                     /evalue="9.70E-32"
                     /label="AMK26_RS30870_Abhydrolase_1.1"
                     /locus_tag="AMK26_RS30870"
                     /protein_end="281"
                     /protein_start="40"
                     /score="102.4"
                     /tool="antismash"
                     /translation="PVLLLLHGFPSASHQFRRLIDTLGRHYRLIAPDYPGFGHTRTLDG
                     FTYSFERLTDIVEGFTEQLGLTRYAMYLFDFGAPVGFRLALRHPERVTGLVVQNGNAYA
                     EGLSDAARDFTALTPDTPGAEQTILGLFTLAATRAQYEGGTADPTLVAPEGWLLDQYFL
                     DQPGRKRAQLALAYDYKSNIAAYPDWQAWLREHRPPTLITWGTGDPFFPEPGARAYLRD
                     VPEAELHLFPTGHFALEDH"
     gene            17283..17870
                     /locus_tag="AMK26_RS30875"
                     /old_locus_tag="AMK26_30390"
     CDS             17283..17870
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005311924.1"
                     /locus_tag="AMK26_RS30875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30390"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_073758749.1"
                     /transl_table=11
                     /translation="MRDSEPLTGEPLALDLVNTRPATAGGRTDLLDTPERLAAWLALEE
                     ARMGPETGGDVPTEADLAAIHAVRAHTERAVHALLRGQEPPAAALRGLTDAQRVAPAVR
                     ELTWDGGRVTPTVRRTGPLGIRLAALLAEAAADLLTDPAIGRLRECEADDCVMLFLPAN
                     PRRRWCSAARCGNRARVARYYQRHKQAAGREQ"
     gene            17951..18424
                     /locus_tag="AMK26_RS30880"
                     /old_locus_tag="AMK26_30395"
     CDS             17951..18424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947786.1"
                     /locus_tag="AMK26_RS30880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30395"
                     /product="hypothetical protein"
                     /protein_id="WP_073758751.1"
                     /transl_table=11
                     /translation="MAKDKSTFLLPRGATGFLRPKDGPLPDTDLRAFRTALYAVARTTG
                     GRVGEVEEQAYPRTFHSASVHDGTDENIILCHAHYPWVAFATERRDWYDEEFAAPPPWA
                     QTFTDEGFLVFARERLTTPLSGVDTSVLTQGEWRQVRSYGITTLGGLLFNAWD"
     gene            complement(18565..18966)
                     /locus_tag="AMK26_RS38150"
     CDS             complement(18565..18966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310709.1"
                     /locus_tag="AMK26_RS38150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_241838138.1"
                     /transl_table=11
                     /translation="MISDASRRVNMRHVANTGAALAATLLPLAAAVVLAKTMAGDPLAP
                     VNALITTGGQRARISPSVWRRCGRATLSEWKGEWKGETPARTRCGRSVPRRPWRRSVER
                     LRTPAVLGASGAATAEEQGESRADAGQSR"
     misc_feature    complement(18961..18976)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.45"
                     /tool="antismash"
     gene            complement(19177..19617)
                     /locus_tag="AMK26_RS30890"
                     /old_locus_tag="AMK26_30405"
     CDS             complement(19177..19617)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133913.1"
                     /locus_tag="AMK26_RS30890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30405"
                     /product="hypothetical protein"
                     /protein_id="WP_241838139.1"
                     /transl_table=11
                     /translation="MHSSLPAWSGARVGDEVYALHVNRCVVYVVSRMRVTDMERRQCCG
                     NTPATWQDPAFPGHGDWSMLGADGCGAAAVHVDATPVRFDVPVPGDLLATLTWRNRRGH
                     TRGLKYVTADGRLERSISLQGFYRLTSESAGELAALVGNAAP"
     gene            complement(19869..20519)
                     /locus_tag="AMK26_RS30895"
                     /old_locus_tag="AMK26_30410"
     CDS             complement(19869..20519)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004937583.1"
                     /locus_tag="AMK26_RS30895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30410"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073758757.1"
                     /transl_table=11
                     /translation="MSSRSAAAKAAPRRSRRSFDRDQALAAALREFWTHGFDATSVASL
                     TKAMGINPPSLYAAFGDKRQLFDEAVQLYVHTYGAPPPQGPDAYSAIAAMLRHLAADYA
                     DASHPPGCLIITGATNCTPGSQDVKDKLRAMREDTKASIAACIRTDIDAGRLPADIDAD
                     GLAAFYAAVIQGMNQQACDGAGRETLDRIVDAAMAAWPDAPDTSGAKSPSPPS"
     misc_feature    complement(20607..20625)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.69"
                     /tool="antismash"
     gene            20647..21429
                     /locus_tag="AMK26_RS30900"
                     /old_locus_tag="AMK26_30415"
     CDS             20647..21429
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-243). E-value:
                     1.8e-23. Score: 75.4. Matches aSDomain:
                     nrpspksdomains_AMK26_RS30900_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718473.1"
                     /locus_tag="AMK26_RS30900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30415"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_073758759.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-16, bitscore:
                     56.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.6e-15, bitscore: 50.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.1e-08, bitscore:
                     29.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPTPVAFARTVRGSGPGLLLAHGAGGGIEANYGPIMEGLAARH
                     TVVGVDYPGSGATPKNQGDLDVDELAEQLVAAADAEGLDTFAVSGYSLGGPVAIRLAAR
                     HPERVTSLLLSATFAHADTRTDLAASIWHQLFEAGRHDVLAEYLNLMALGEPALNAMTP
                     AQVSGAAGQLASALPAGTAEQVDLVRRVDVRGDLADIHVPALVVVTTADPLISPALQRE
                     LAAAIPTAEVAELPAGHLPFTECPEQWLKLITDFLARH"
     aSDomain        20704..21375
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS30900_Abhydrolase_1.1"
                     /evalue="1.80E-23"
                     /label="AMK26_RS30900_Abhydrolase_1.1"
                     /locus_tag="AMK26_RS30900"
                     /protein_end="243"
                     /protein_start="19"
                     /score="75.4"
                     /tool="antismash"
                     /translation="LLLAHGAGGGIEANYGPIMEGLAARHTVVGVDYPGSGATPKNQGD
                     LDVDELAEQLVAAADAEGLDTFAVSGYSLGGPVAIRLAARHPERVTSLLLSATFAHADT
                     RTDLAASIWHQLFEAGRHDVLAEYLNLMALGEPALNAMTPAQVSGAAGQLASALPAGTA
                     EQVDLVRRVDVRGDLADIHVPALVVVTTADPLISPALQRELAAAIPTAEVAELPAGHLP
                     FT"
     CDS_motif       20911..20958
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK26_RS30900_0001"
                     /evalue="1.20E-03"
                     /label="NRPS-te1"
                     /locus_tag="AMK26_RS30900"
                     /protein_end="104"
                     /protein_start="88"
                     /score="11.4"
                     /tool="antismash"
                     /translation="SGYSLGGPVAIRLAAR"
     gene            complement(21610..22146)
                     /locus_tag="AMK26_RS30905"
                     /old_locus_tag="AMK26_30420"
     CDS             complement(21610..22146)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088443.1"
                     /locus_tag="AMK26_RS30905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_30420"
                     /product="hypothetical protein"
                     /protein_id="WP_073758761.1"
                     /transl_table=11
                     /translation="MSAFIQQLPALIGVVIGALGSYLASTRGDQARFRREQAAQWEERR
                     MTAYADYARSLKKSVTLAYRVAAHLGNDPHPHPLSPEEAAPHLADATDARDPAGEALLM
                     LGTPDVVEKAREWVVVVMEMEGFLRDRTHCPETWSTLLKRQRAAREGYYVAVRRDLALP
                     PGHSGEWRRAQPRTP"
     misc_feature    22188..22202
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.76"
                     /tool="antismash"
ORIGIN
        1 ggccctgcgc acggtgggct ggcaggccac gaaccaggac aagatcaccc tgtcgccgcg
       61 cccggcgtcc tggccggcac ccgtgtccct gacggtgccc ggcggcaaga ccgaggcggg
      121 caccctggcc tgcgcgaccg tggccatgtg atcagtgtgg cctcgatgtc caggacgggc
      181 tgcgcagttc gtgtcctggg gctgtcaccg caggtatgcc ctcaccggtt tcggcggcct
      241 gcagccagga aacttcccgg gcaagcagcg cgggccgctc gcagcgaagc gactacgcat
      301 tgtccgtgtc ggcgagcagc cgccaggctg tggggctgtc gatcaccgcc ctcgacaggt
      361 ccagccggtc cgcggcccgc agctcggcca acagcacctc gtgcaggcgt tgccagaccc
      421 ctgcgttgtt ccagtcccgc agccggcgcc agcaggtcat gcctgagccg aagcccagct
      481 cagccggcag ccactcccat cggatgcccg tgtagaggac gaagaggatg ccgcacagca
      541 ccttgcggtc atccagtgcc ttccggccgg ggtgccgatg ccgactctgc cggacaggca
      601 gcaacggctc gatccgcgac cacaactcat catcaatcag ccacggttgg ggaatcacac
      661 ttcctcacac ccaagcaacc gagtcaccca gctggaggac acgctccaac cgcattccgt
      721 taggagctct tagggctccc ttgaggtcga tctgactgcc agccgctgcg gggtaggtgt
      781 cggcttcctg gcatttgttg gcctcgaggt cgaggacggc gacctggtac gcctcgcccg
      841 accccacggc ggtggcatac cagcggccgc tggcgtcgat ggctccgcgg cctgccgcgt
      901 cgcctgcttc gcagcgcggg gcggccttcg attttttgtc gtcgatggag tacacgttga
      961 cgcacgcact gctcttgcag tcgttctgct ttcgcacaac gcgggtaccc gcggtgctga
     1021 gcacggtggc gtacttggcg atcacctggg tgacggactg ggcctgcttg tccagcagga
     1081 cgatgtcggt aagagcgatc ttcccgttgc ccgtcccagc cgtgtcctcg gtggtccggt
     1141 ggacgagcag tccttgaggc gtctgcgcca cgggctccat gccgcagggc aggctgagtt
     1201 tcgtgcggga cgggctgccg ctggtgtcgt gttcggtgat ggtgaagcgg gcctgaacgg
     1261 acgggggcag cttcttccca ctacaggcgg tggcggccgg ctcctcagtg actgcccagg
     1321 tcttgtcgtt gtctgccgcg gggaaccacg cggccgccgg tcccagcagc cgggtctttc
     1381 tcgcggcgac gatcgtgggc ttggcatcga tcgaatccag gacggcgatg cggcctccca
     1441 gattcagcac gatgccctcg gccgccgtgc tcccgtcatt tccctggccg cacccggcga
     1501 caaacaccag cgcgccgacg gccgtcgcgg cggtcaggag gcggctccgg acagtacatg
     1561 ctgcgcgagt tgagggccca gtagcgacgg gacgcgttcc gtggcttgcc cccgcgccgc
     1621 cgggaggccc gccggccgcc ctcccgccgc cggggtgaca ggtccgaggc cgctttgggg
     1681 cttcggttcg cagcgccggc agggaaggcc gccgcccgag ggggcgctgt cgcgaaaggg
     1741 tgcgtccccg tcagtctgcg tccgccgcgg atagagcctc gctgatcaga cgggtggcga
     1801 agttggggtc gtcggtgagg cggttgatgt gctcagcgag caggaagaca gtggcttcca
     1861 ggggagtcat ctcgtcatcg gtccagtacc cgtactgttt gcgccacagg ttggggctca
     1921 ggccggtgcc tgcggcgacg agcaggccgg ccatggtggg gatggtctcg gaagggacgc
     1981 tcttgggcat catccgcatg gtggccacga ggttgggcac cacgcatgcg atgacgtcct
     2041 cgtcgtggtc ctcgtacgcc atccgcagcc acttcatgaa catgaagatc agtgtgcatg
     2101 ccccgtccag tacctcatcg actcccctgg gccccaggga ggcggcgaac tggtcgatca
     2161 gcgcttggtg ttcgggatcg gtcgcggtct tgccttcgta gacggcctgg agccgagaat
     2221 cgatcatcat gagcgctgcg ctcacatcgc cggtgggagc gtgctggggg tcacagggcg
     2281 atgacacaga acttcctcct catcccgacc gcgacgggca gcgcggtatg tccgtacggt
     2341 agacggccga tgaggccgca gtccggtgaa tcccaccgat tgaccccgaa acggtcaagg
     2401 gccctcttcg agcgtcgggt tccctggcct gcccggccat cagcccccgg gcaggccagg
     2461 gtcgtgacca cagcaatggc tccgtcaccg cccaaacact catcaggcag ctcacgacgg
     2521 cgtgccacga accgagcaac gaacaaccga ctttgccggc acgactgggg cgtcacccca
     2581 cgcggaaggc cgagcagggc gccaaaaccg gtgcagggct tggccgggtt cctccgcagt
     2641 acgttcgccg gccaccagcc gcccaagacg cgtgccgcga ggggtgaccc ggtcgtgcaa
     2701 gtgcacccgc cggcggcctc gacggtcttg acctcaccgt gtccgtgggc acggtcatcg
     2761 cctcggtgag gcgggaaggg cacggcagct ccctcgaccc ggccaccgcc cattttctgg
     2821 cccagtcatc gccctccgct tccagaaggc caccgcacct ccggaaaccc cctcagcagt
     2881 gcacagcacc tcatccggtc attgcgaccc tgcacggaag ccccccgcaa ccaggaccac
     2941 cactacgccc ggctcctccg ccgatcagtc tgccggggcg ccagccgttg agcgacgggc
     3001 cgaggttggt ggccttgatt tgggcggtgc aaccgtcggt gcacctgttc acggtgccgg
     3061 cgcggtaaag aggaagggcg cgaaaaagca gtggagcgct cccgatcagc gagacggggc
     3121 cccggctagg ccggggcccc ggcgaaggtc agctggtggg gaaggtgtcg ggggtgctga
     3181 tccggctctt gagcagcgcc ccggactcgg tcagcacgcc gctgctgctg tagtccgtgc
     3241 cgttgcaggt gccgggtttg aaggcggcgc tgccctcatt ggcgtcggag taggtccagt
     3301 tcgcgtagcc gatcttcagc tgatcgagca ggtccagcca ggccgtggtg ctcgcccggt
     3361 ccaccgctcc cccgccggtg taggtcaccg tgccgaactc agtgacgaac agcggcagct
     3421 gggaggccgc ccggctcacc gtggcgcggt agttgtcctt gtggctcgcc gcgtagaagt
     3481 ggaacgcgta catgatgttg gtggcgttga cgggattgtt gacgacctcg ctctcgttgg
     3541 agccgtccga gactcccagc gaggaccagc cgcgggtgcc gacgatgacg acggcgtccg
     3601 ggtcggcggc ccggatcacc gggatgacct gctcggcgta gctcttgatg gccgcccagc
     3661 tcacgccgtt gggctcattg gcgatctcgt agatcacgtt cttcttggcg gcgttgcggg
     3721 cggcgacgga cgcgaagaac gtcttcgcgc ggtcgaggtt gtagttcggg tcgcccggcg
     3781 tcagggtgtg gaagtcgatc atggcgtaca tgccgcgcgc ctcggccatg tcgacgaggt
     3841 tgttcacgcg gctggtgaag cccgccgggt ctgtctcata accgctctcc tgcacataca
     3901 tggcgatgcg cagcaggtcc gacttccagt tcgtcgccag cgcgtccagg gacgcggcgt
     3961 tgtaacactt gttgaaccac tggatgccgt gcgtgctcat gccccgcagt tggatggggc
     4021 ggttgtactg gttgcacagg ttcacgccgc agacgtggag ctgtccgttg atatcgacgg
     4081 gggtgccgtt gcccggtgtg ggcgggggct cctcctcgac ggagcccgta caggtgacgc
     4141 cattgagcgt gaacgccgtg ggcttggggt tggcggccgt gaaggagccg gtgaatccaa
     4201 ggtcggtggc cgcgccggtg gccagagtgc ggttccagtc gacgccgacg gcggtgaccg
     4261 tggagccgga ttgcgaccag gtggcgttcc agccctggac gatcttctgt ccggcgtccg
     4321 gcatggtgaa cttgagcgtc catccgttga cgggggcgcc caggttggtg atcttcactc
     4381 cggcctggaa gccgccctgc cactggttgg tgatcgtgta gtcgaccttg cagccggtgg
     4441 cggccgcggc ctgggggccg gtcagcgcgg tgaggcccag gaccgtcgca caggtggcca
     4501 gtaaggccaa aacgcgtttc atggcgttcc tcctcgtatg aagtggacac agcatgatgg
     4561 gagcgctccc aaagcccatc ggcccgagac cgtacaccgg cgcgtcgatg cgcgtatagg
     4621 cattcgacag tcgaaagatg cggtggtgcg gtgaccgctg ctcagacgga cgtcccggag
     4681 ccggaacgcc ggtgcgaaac gtggacggga tgccctccag cagccggcgg tggtcccggg
     4741 gccggcccga ccggtgagat cactgcccac gtggcatcag agatccccct ctcacggccg
     4801 ggccaagacg cccgtgctgc gggccgcgcc gcgtagtgac tgtctgccgc ggcctggtgt
     4861 gctgctgcgc cacggccaag gccggcgtaa cggtcgccat tggtgggcag gctcgtaagg
     4921 ccagaatgtg ccgcagtcgt tttcagccac acctctaccc tgtggccgaa ttcgggtgca
     4981 tcctgtgctc acggcactcg agtccccgtc gggtagccgt gtcggccccg ccccgggtcc
     5041 ccgcttgggc gaggccgcgc cgcctcccgg ctccccgcgg gaggccaggc gcatgcccca
     5101 aacgaccgga ggcctgatgc cgaacgagga ccgcgccagg gccctgcctc tctcacatct
     5161 ccccactgcc cacgcgacga ccactgccac tgagctgtcc ctgacggacg aggaactgct
     5221 ggaaaggtac ccggccgtca gaggggttgc ggaacgctgg accgtactcg cgagggaatt
     5281 gagagaatcc ggctgatagc tgcgcgtcct tcgtgaccag cgccgtcctg ggacgatgat
     5341 ctgcagggtc tcgccactcg ggcctgccgg actgcggccc tgcacgatcc acagggacag
     5401 catgcgatca gccggtggat gaatacgagg tgacggcctc gtccttgatc tcttccgggt
     5461 cccggtagcg gcccgcacac atccggcgcg gatcagggcg agtcgtactc agcgatgctg
     5521 tcgggtttgg gctggtcaac gagcagatca gcggcatcca tcagtggacg caacccttcc
     5581 gggtcgtcct tgaggaaccg cgcggccgcg tcgatcgcga ttccatccca gggtgatcgc
     5641 gtacgtcaag gacgcttcgg accgagccgg gtgcgcacct cgccatgcgg aatccacatc
     5701 ttcatgcctc tttccagggc cgtacgcccc ggcgggcaga gcgcgggatc tcgacagcct
     5761 tggccggcag gcctctgcag ggatgcctgc tcaggagagg gcggtcggtt tgcgaggcgg
     5821 cgggacggcc cggagcagct cccacagggg acgcgagccg gacgcccaca ctccgagggt
     5881 gtggcggtcg accacgtgca gccgctgctg cttggcgaag accaccgccg gtgcggtgac
     5941 cctgccgttg gtcacgatca ccgcgacatc ggcgccgtgg acctggcggg cggtgccgtt
     6001 gagcacctgg agatgcggag tgcccaccgg ggagccggcg agcccgttgc ggcggtgctt
     6061 gcattggatc acccagcgac gcccgtaggg gtcagtggct ttcacgtccg cgcccagatc
     6121 tcccccgccg cccacccggg ccgcgtccgt gcagccgtca cggcgcatca ggtcccgtac
     6181 cgcgtcttcg aaccgggtgt ggtgcagggc gtccagctgg gacagcccgt agcgcaggcc
     6241 ctgcgcgcgg accgcttccc accgcgctct ctgctgcttc tggtagagcc ggccgccgcc
     6301 ggccagcccc gcgagcgtgc cggggacgat caggacccac cagtgggcca gcagccagtt
     6361 gacgagggcc accaccaggc cgacggccag gcccacggcc acgagaaggc cgatcagccg
     6421 gtcatctgca cgctgtcgcc gcttgcccgg ccttcgggtg cgcccccgcg ccggcgggcg
     6481 cctggtcgcc ggcacccgtc ccttgcgtgg gcgggtgctc atcggctggc ctgggtgacg
     6541 ccggtcgcga gctgccccag aatgttcgcg attccctcgc ccactccagt gggagcgatc
     6601 aggacaccca acgccaggac gatgacgacg gtcagcttct cgtcgacgcg gctgcgggcc
     6661 tccgtacgcc gccgcagccg caagacgacg atgactgcga gcagcaccgc cacgttgatg
     6721 gtcagcaacc gtccagacct cccccacgac cggccatcac cacccgggtg gcagtgcgcc
     6781 acccgcgcct tcttatgtag ccgcacctca gtgctgtcgg gcgccagttg ccgacgaatg
     6841 gcacaaagca atcgcacttg gccggatacc gcgcggcgga tcagtcgtgg acgtgcacgg
     6901 cgacgtacag gtctcccggc actccgccat tgctgccctc gggccgccga gcgctcggac
     6961 ccggatccgc tgtccgttcc tgatgcccgc gtgaacgtga agcgcatcgg aatgatcgcg
     7021 ccgtctgcga cggcgtccgg gcgggaggcg cgcagcggcg cgggctgctc cttgagggtc
     7081 tggtcgacca ggtgtcagga ggtgccgggc cctgatgaga cctccgccca gtggtgcagc
     7141 gggacctcct cagtcgttca gtagcccccg atgtcctgaa catgctcgca gtaggtgcac
     7201 tggatggcgc acggatggga tgccaggtga tcgactacga cagcgaggcc cgggactacg
     7261 acacttcccg aggcggcgaa ccgcgagcgc aggcgtcggc ggacgccttg gagcagttgc
     7321 tgccgcaagg tccctgtacg atcctggaca tcgcgtgtgg cacgggcatc gtgaccaggc
     7381 gagccgacgg ctctctgtgc taccggacca ggacgcgccg cgcccgggcc cgttgtatcg
     7441 cctcatcgcc ctgaaggcgt gacactccac cgcttgccgg gaggggaact ctccggacgc
     7501 ggacgcagcc ttcgtcatcg ccgggcacgg agccgggcac ggagccgggc ccgccggagg
     7561 ccacatgcac ccaccgcgct gccggcggtg gcccgggggc ccgggccacc ggtggtgggc
     7621 gagccgcagg cccagcaggc ggcaccgccg acgccccggc acgtgttccg tcattcatga
     7681 cagcccggcc aggcgggccc gatcacctcg tggctacgaa tcggtgtcca cgtacagccc
     7741 ccaggcaccg cggctggagc tccacgcgca gtaccagtag ctgtaggcgg agttggctcc
     7801 atcggcctcg caccgcgcca ggctggagta ccagccgacg cggacgatgg cggagatgct
     7861 gatcggtgcg gctgccgtcg tgttgctgtc gacaggtgcg ggagcggcct gcgcgggagc
     7921 ggccaggccg cccagcacaa gcgcggaccc aagggccgca ctaccagcga ggacattgcg
     7981 catacgcata actcatcctt ctctctcgac ggatggactc tcgcatctcc acgggctgat
     8041 gccggacatg cttcgaaacc cgtgaacgcg ttcgatcggc gcgggcacaa gagcactgcc
     8101 cgatcgcggt cgatgtcccg gatgccgaga gcgagagttc ccggccttgt cattccgcgc
     8161 agggctgttg acgatgcgcg cacacctcga gcgtcaggtt tctgtagtcc cgcggcggta
     8221 tcgcgtaggt ggcccggaac aggcggctga agtgtgccgg gtcggtgaaa ccccatcggg
     8281 cggcgatggc ctggaccggg tgggcgtgga ggtgcgggtt ggtcaggtcg aggcggcagc
     8341 gttccaggcg gcggtggcgt atccaggccg ccggcgatgt gtcgtcctcg gcgaacatct
     8401 gctggaggtg gcgcagcgag atgtggtggg cgtcggcgat catctggggc gtcatggccg
     8461 gatcggcgag gcgctcttcg acgaatgcgc tgatccgggc ccgtagggcg gtcctgcggg
     8521 cctctgggct cagcgctgcc tcggcctcca ggcaccgggc gatgacggat gccaggaggt
     8581 ccacggtgac cgaggcaaga atgaggatgt cggccgcggt gaactcggtg gcgcgtgcgc
     8641 cgatgtcggc cagccagcgg ccgaacaccg cgcccatacc gcggtgcccg ctgatcggga
     8701 cagcgaccag gtgctgcacc gtcttctccg gcagcggcag cagcccgcga ggacactgca
     8761 ccgtcacatg cgaccaactg tccggatggg cgtggacatc gccgtggaag ggacgcctgc
     8821 tgtccagcac catcaggtca cctgtgcgca gcgccgtgtc acccccggca gggacatagt
     8881 gccccttccg ccgcggaagt agttgatctg atacacctcg ggatcggact gccgtaccag
     8941 cttcgctgtc cgcacgacct ccagatacgg gtaggcaagc acggagacct gtaactcccc
     9001 aggtccagga cacgcatctt cgcgcggaag tcgtcctggt cgttgctgcg caaccgattg
     9061 cgcatatgcg aacggctcgt cacctcctcc cacggccgaa ccgctccggc gctgccgcga
     9121 cctccgtgct gaactccgtc accagcattc tcggcccccg tatcccatcc cccgcggcta
     9181 cgcacgtggc aggggtgacg tgcacggtcc agtagcaatt caggcaacac cgccccacac
     9241 ttcctcgcag gcgtcccgcc aggacgcatg gagcttcaga agcggtcccg aggacaggcg
     9301 gtacctgtcc gtcgacgcgt tcggcggccg cgggtacgtg ccgttcgaga ccaccggtct
     9361 caactccggc cgatggacgg cgtccaggga ctacgacctg ccttccggtc cacggcacgg
     9421 cagcgtgacg ccggtcaccc gggcgggcca gccgcccggt cccatggccg gaaccagctc
     9481 cgtcgcgtgc tggtcgaggg tgaccacgcg tgaggggctg caccagttcg gtcttctcgc
     9541 cgcagcgccc cgaccgggcg cctgacgccc ggcgtgcctt gtcacgccgc tgccgaggcc
     9601 cgttccccat ccggccaacg tgactgctgt ggcagtgatt gccagcagcc tctttcccac
     9661 ccgaccgccc acccaagccc tcttattgcg acaatgtggc aataactaaa tccttgcaga
     9721 agttcacgct cgtaggccag agtgaggccc aagggccccg cacgggggac ctccctacgg
     9781 attgaggagg tgcaacatgc agtactccaa cgaggagctg gctgaggtct tcgaggtcga
     9841 ggagatcgac gaggagaccg tggtgagcgt ggcccaccac acctgatcgg ccctgccgac
     9901 atgaacgggg cgcggggtgg cggtctcgtc cggccgaaac cgttccggtc cgcgggctcc
     9961 gccccgcgcc catcacgttt ttgaaacggg agagttgcac gtgctcgcga tcagcgacca
    10021 gggaacgccg gcaccggcca agggatacct ccgcggtacg caccgcgtgg tgccgcccga
    10081 ggacacctgg cagcggatcc gcccgcagct cgcccggtac ggggtgaccc gggtcgccga
    10141 cgtgaccggc ctcgacgaca tcggcatccc ggtcttccag gccgtacgcc cggcctcgcg
    10201 caccgtgtcg ctctcccagg gcaagggcct cacgcccgcc gccgcgcgag tctccgccac
    10261 catggaggcc atcgagctct ggcacgccga gaacccaccg ccggcgtcac gcacgtccac
    10321 cgcgcgggcg ctggacctgc cgtatgagct caccgccctc gatctcgccg agggctccct
    10381 gctccacgcc gacctgcccc tgccctggct ggccggcgaa gggctgctca gtgggcaacc
    10441 gactctggtg ccggagcccg ccgtacgcct cgaccacacc taccgcgcgg agtgggcacc
    10501 gcccctcttc cgcaccacca gcaacggcct cgcctcgggc aacacccttg ccgaggcgac
    10561 cgcccacgcc ctcgccgagc tgtgtgagcg cgacgcgctg gcccggctgc gtgcccggcc
    10621 ccgctccgac tggcaccgcc tcgacctcgg ctccgtccgc gacacggact gtcgcttcct
    10681 cctcgagcag tacgccacgg cccaggtgtc cgtcgacgtg gtggtggccg aacgcgaccc
    10741 ggcctgcttc gaggtacgca tccgctccga ggcccacccg gtgacctaca ccggcgccgg
    10801 ctgccacctc gacccggcca tcgccctgac ccgggccctg accgaggccg cccagagccg
    10861 cctcaccgcc atcgccggag cccgcgacga cctcccgccg gtcctctacc gtacggccgg
    10921 cgaccgtccc ctggtcaggg aggacctcgg aacccggacg acgccatggt gggacgcgcc
    10981 ggcagggggc gacttcgacg ccgacatccg cgctctcgcc ggctccatcg ccgcccgcac
    11041 cggaaccgaa ccgatccgcg tggtcctgcc gagcccgacc ggcattcccg tggtcaaggt
    11101 gatcgcaccc ggcctggact tcgacgaccg tacgaacgtc agctccggcg ccggccggta
    11161 ccgttccccg gacggagacg cacgatgagc accacccacg tgtacgccgg accctccctg
    11221 gacgccgagg ccgtccgcgt actgctgccg gacgccgtgg tgcacccgcc cgtccggcac
    11281 ggggacctga cagccggccc ggccggtgcc ggggaccggg tggtcatcct ggacggccag
    11341 ttcttccagt ccgcgtcggt gcgccacaag gagatctgcg aggtcatcgc ccgcggcgcc
    11401 gccgtgtacg gggcggccag catgggcgcg ctgcgggccg ccgagctggg gccgtacggc
    11461 atgagaggca gcggcgtcgt ccaccggctc tacgccacgg ggctgatcga acgcgacgac
    11521 gaggtggccc tcgtccacac cgatgtcggc gacggctccc ggccgctgac cgtcgcgctg
    11581 gtctcggtcc gcgtcgcgct gcgccggatg gtccgctcgc gtgtgatcgg cgccgacgac
    11641 gaggcccggt tgctgaccgc cgccgaccac tttcccttca ccgcacgcac ctggcgggga
    11701 atcctccacc aggcagacgg cgtgacccgg gcgatcgccg aggcggtccg cgagatcgtc
    11761 gacggcccgc agcacacctg ggacatcaag acccaggacg cccgggctct gctgtcccgc
    11821 ctcgcgcgga ccccggtacc acctccaccc gccaccacgg cagcccgcgt gccgacgacc
    11881 gtacacatgg agaactggcg gcgcgccgcc gactccgacc gcctcgccct cctcacggca
    11941 gcgcagatct acgcggacga ctacccccgt ctgcaccacc ggacggtgct ccagcttctc
    12001 accggcaagc gcgacgagga catacacctg ttggagcgct acgcggccga cctcgcccgg
    12061 cagcgcgggc tgctgtccgc caccggcctt cggcactgga tcggcacgga ggaagcggcc
    12121 ggcaccgacg agcgcaccat cgcgcgagct ctggtgcgtt cctatcgctg gtcatgcggt
    12181 tcggccccgc tgccggctct cgccgacgcc gtccgcgcca caccgggcac agcccgcctg
    12241 tacgagctca tcgccgaggt cgaccggctg aacgcccagc tgaccgaccg tggctatccc
    12301 ctgcggcggg tctcacgcgc cgcgctgcac cggcactgct gccgccactg gaacaccgcc
    12361 gcgctccttc ccgcgctcta cgaccggggc ttcaccggcg tggcggacct cgaagaccgt
    12421 gccgtgcgct tcgccccgca cctgggcctg gccgaaccgc ctcggctgcg gctgctggac
    12481 cgctgaaccc gcccgataca ggagtacgtg acatggtgct ggaccgcctc gtcagcgaca
    12541 ccgccgaact gcgccgagcc tgggagagca caccgctcca ctcccgtggc ctgggcgact
    12601 tcgacgacgt cttcggcctg gccctcgccg aggacctgat cgtgggccgc ggcctgcgga
    12661 tcccctacct ccggctgctg cgcgacggcg gatacgtccc cgcgtcccgt ttcacccacc
    12721 gcaccgggac aggagccggc caggccgacg gagtcgccga cccgcacgcc gtcctccgcg
    12781 aaatggaacg cggggcgacc gtggtgttgc gcggcatggt gcgctactgc cccgaagtcg
    12841 cctccttctg tgagcggttg tcggccgaac tgggcctttc cacctcggca ggcgcctacc
    12901 tcaccccgcc gcactcgcgc ggcgcgggtc cgcactacga ccccatgtcc gtcctggtcc
    12961 gccaagtgca cggggtcaag cactggcgcc tccaggcgcc cccggtgcag tggccgcgta
    13021 cccttcccga gccggggaag cactacgaca ccccggtgat cgccgaactc gacctgcgtc
    13081 cgggcgagtc cctctacatc ccacgtggcg tcgtccacga cgcctggacc accgacagcg
    13141 cttccgtcca catcaccttc agcggcgaca ccccgccgat gtgggccgac gtcctgcacg
    13201 acctcgtcga ccaggccgcc gccatcacgc ccgccctgcg cgagaccttc ccctggcgct
    13261 tcgccgacgc cccggacacc gtctccaccc gggccaaaga atgtttcgcg gcgttgcggg
    13321 ccttcctcga caccgtcgac accgacgcac tggccacccg catcatcgac cgccatgccg
    13381 ccctccccga cccggcaccc cgtggccggc tcgcagcagc cctggccggc accccgctca
    13441 gccaggagcc gccccggtga cgtcgaccgc cacccgcgac acccgcttcc cgcgcctcct
    13501 cgccgccgcc accctgtcca acctgggcga cggggtccgt gtcgtcgccc tgcccctgct
    13561 ggccgcggcc accacccgcg acccgttcgc cgtcagcgcc ctgacggcct gcgccttcct
    13621 gccctggttc ctcttcggcc tgccgatcgg cgccctcgtc gaccgcagcc ggccggagac
    13681 cttcatggcc tgggcgaaca cggcccgcac cgtgatactc gccgggctct ccctcgccct
    13741 gctggccgac gtgcgctcca tgcccctgct gtacgtgctg gcgttcctac tgggcatcgg
    13801 cgaggccgcg tacgacaacg ccgcccagtc cctcgtaccc cgcatcgtgg cggacgagaa
    13861 gctggagaag accaacagcg ccctcatcac cgccgaacgc gtcggccagg acctggccgg
    13921 cccggccctc ggcggtctgc tcttcgccgc ctcgcccgtc ctgcccttcg gcctgaacgc
    13981 cgccgccatg gccctcggcg tactcctgct cacccggatc cgcaccttcc cgccaccgtc
    14041 cccaccccgt gggcctgtcg tccgcacggt ggtcaccgac gcggcggccg gcatgcgctg
    14101 gctgtggcga gcccccctca tccgcacgat cgtcctgacc ggctcggcgc tcacgttctt
    14161 caccatggcc tgggaagcca ccctcgttct gctggcccgc ggccccatgg gtgtgtcgga
    14221 gaccggctac ggcatcatgc tcgcgatcgg cgcgatcggc ggtgtcgccg gttccctgct
    14281 cacgccggcc ctcgtacgcc gtttcgagcg ccgtcccctc cagatcgccg cgatcgctgt
    14341 caccgcggcg ctcgacctcg ccctcgcgat ccacccccac cccgccctgg ccgccctcgc
    14401 ctggggtggt accggagccg ccttcgccgt ctggaacgtc ctctccgtca cactgcgcca
    14461 acgcctcgtc ccggccgagc tgctgggccg cgtcaacagt gccaaccgaa ccttctccat
    14521 ggccgccgtc cccctcggtg ccctcacggg cggcttcgtc gccgacaccc tcggccttcg
    14581 cgcgcccctc tggctggcgg ccgccgccct gaccgtcctg gccttcgcgt acgccgtcgc
    14641 cacccggaac agcgtcgtca gcaagcccaa tccgggcccc gatgacaagg ccggggagcc
    14701 gcggtgatcc gcgttcgggc agtggggccc gagcgggttc cgtatcgagg ggcgcctcgc
    14761 cgattggagc ggcatgggcg acggggggac tgctggttgg aggagggggt ctggaactct
    14821 ccggacctcg accccgtcgg tggcgatcgt gggcagccga tggccgggtg cgccgaactg
    14881 tacctggtcg gcggccgcgc ccggtgccgg cccggcgcgc ggcggcgaat gcgagcccgg
    14941 atacccggct tcggcaggaa atctccggcc tccgcttggc gaagaggccg gggatttccc
    15001 tgtccttcga agtgcaatca gcctcgcgtg ttccggcggg ctggtggagg cgtcagcaat
    15061 ttcccgacag gtcggcccag gagttggacc gggcccagga gttgagcttg ctccaggtgt
    15121 tcggtccgac aactccgtcg atggtgatgt tggagcagtc ctgaagcttc cgcacggccg
    15181 cacgggtgtc ggagccgaag tagccgtcca ccgtcagggt cgtgttgtac agcgaccagt
    15241 tcagctcgca ctgcacctgc ttgacggcca gcttgtaggt gttgggcgcg tacgacaggg
    15301 tcggctcgct gctggtgtac tcgcagcggt tgggaatgat ggccgcggag gccgagggag
    15361 cggtcgccat ggaggcgccc gcggctatgg ctccggcgaa gagcagcgat gccgccccac
    15421 gcgcgattcg ccggtgggag gtgctgggtg aagaagacat gaattccccg tttctgttcg
    15481 gtcgatggtg agctggagcg gatccgatcg tcggcgcgat cactgccgcc ggcggccgag
    15541 attccagaca gcgaggatgc ggcttttcat ggttccgtgt gccgtatgga actcggacgg
    15601 ctgaaggctg ccacacacgc acccggcacg cgtcaaacca gcgcggtaga cccagtgagg
    15661 taggccggtc gtctgaatcc acccagcacg gtaggtttcg tagctccgct gccgtcagca
    15721 cggcgcggca cggtcaccgt cgccgcgatg cggctgtgga tccgcgggcg tgctgtccgg
    15781 caggtcaacc gaagccggcg gcgtgtgccg gtctgggcgg cctgttgggt gacggacgac
    15841 gctgccggac tgggtgccgg actgcctgtg cgggcggtcc gcgcgggagc cgatggccgg
    15901 cgtcccgagc tctcccagtc cgcacgtccg cctgcctggt gcagagcgtg tggcgatggt
    15961 tcacggggct gggcttgatt gcgtggctac gcaggcgcac ggggcggtcg ttgtcgaagc
    16021 atcgccttcg gtgaattcac ggcggtcgtg aacggaaaca agacggtgga gctggagcag
    16081 cggcgggtgg agctgctgcg gcgggaggac gagagcgacg gtgcgccgcc ccgcaccagc
    16141 attgatcgca ccaagggcac ggcgtccatc gtgttgccac aggaagcgga gggcccgtgc
    16201 gctgagggaa acaggcgcag aaccgtccgc gctgggggcg tgcaagcagc tcaccgcgtg
    16261 ccggaacgag cgctcctggc gacgggggcc agggggccag tcaggtcggg aggcagttga
    16321 ggaagcccgc gacgagcggg gcgatgtcgg gcaggtggtc ctccagcgcg aagtggcccg
    16381 tggggaacag gtggagttcc gcttcgggta cgtcgcgcag gtaggcgcgg gcgccgggtt
    16441 cggggaagaa ggggtcgccg gtgccccagg tgatgagggt gggcgggcgg tgctcgcgca
    16501 gccaggcctg ccagtcgggg taggcggcga tgttgctctt gtagtcgtag gcgagggcga
    16561 gctgggcccg cttgcggccg ggctggtcca ggaagtactg gtcgagcaac cagccctccg
    16621 gtgcgaccag cgtggggtcg gcggttccgc cctcgtactg ggcgcgggtg gcggcgaggg
    16681 tgaacaggcc caggatggtc tgctcggcgc cgggtgtgtc gggggtgagc gcggtgaagt
    16741 cgcgggcggc gtcggacagt ccctcggcgt acgcgttgcc gttctgtacg acgagtccgg
    16801 tcacccgctc ggggtggcgg agtgccaggc ggaagccgac cggggcgccg aagtcgaaga
    16861 ggtacatggc gtaccgggtc agcccgagtt gctcggtgaa gccctcgacg atgtcagtca
    16921 ggcgctcgaa ggagtaggtg aagccgtcaa gggtgcgggt gtgcccgaag cccgggtagt
    16981 cgggggcgat cagccggtag tgccggccga gggtgtcgat cagccgccgg aactggtgcg
    17041 aggcggaggg gaaaccgtgc aggagcagga ggaccggggc gtcggcgcgc tcgggcagcg
    17101 actcccggta gaacacctcc acgccggcga cctcgacgaa gcggtgggtg gagcgggccg
    17161 gcaccggtat gcggggaagg gctgcgggag cggtcatttc acatgcctcc atgatgtgtt
    17221 tacgcattag gtataggcgt gcgcacgcta atgtgtcaac cgactcctgt accgttagcc
    17281 atatgcgtga cagtgaaccg ctcaccggtg agcccctggc cctggacctc gtgaacacgc
    17341 gccccgcgac cgccggaggc cgtaccgacc tgctcgacac gccggagcgc ctggcggcat
    17401 ggctggcgct ggaggaggca cggatgggcc cggagacggg cggcgacgta ccgacggagg
    17461 ccgacctcgc ggccatccac gccgtgcggg cccacaccga gagggcggtg cacgccttgc
    17521 tgcgcgggca ggagccccct gccgccgcgc tgcgcggcct caccgatgcc cagcgcgtcg
    17581 cgcccgccgt ccgcgaactg acgtgggacg gcggcagggt cacgcccacg gtccggcgca
    17641 ccggcccgct cggaatccgc ctcgccgccc tgctggccga ggccgccgcc gacctgctca
    17701 ccgaccccgc catcggcagg ctcagagagt gcgaagcgga cgactgcgtg atgctcttcc
    17761 tgcccgccaa ccctcgtcgc cgctggtgct ccgccgcccg ctgcggcaac cgcgcccgcg
    17821 tcgcacgcta ttaccagcgc cacaagcagg cggccggccg ggagcagtag gcccggggcc
    17881 gcccgccggg ccgcgcgctc gccagcaggg ctcacggccc gtacgcgaag gcacggggca
    17941 ggatgtgcac atggccaagg acaagagcac attcctgctg ccgcgggggg cgacagggtt
    18001 ccttcggccg aaggacggtc cccttcccga taccgacctg cgggcattcc gtaccgcgct
    18061 gtacgcagtc gcccgtacca ccggaggcag ggtgggcgag gtggaggaac aggcgtaccc
    18121 ccgcacattc cacagtgcgt ccgtccacga cggcacggac gagaacatca tcctgtgcca
    18181 cgcccattac ccctgggtcg cgttcgccac ggaacgccgc gactggtacg acgaggagtt
    18241 cgcagcaccg ccaccctggg cccagacctt caccgacgag ggttttctgg tcttcgcccg
    18301 tgaacggctc accacaccac tctccggggt ggacacttca gtgctcactc agggcgaatg
    18361 gcgccaggtt cgctcctacg gcatcaccac tctgggcgga ctgctcttca acgcatggga
    18421 ttgagggaga gcaggtggtc acctcgccgg acccgcccgc gaagcgccgg gcgtcgtgcg
    18481 cgccctgctc accgcctggc aggagaacga cgccgccgcg caccacgtcc tggcgcgtac
    18541 ctcaaccgga tgggcaccgc cgcgtcaccg gctctgcccc gcatccgcgc gggactcgcc
    18601 ctgctcctcc gcagtggccg cgccggaagc cccgagaacg gcgggggtac gcagccgctc
    18661 cacgctccgg cgccatggcc ggcgcggtac tgatcgcccg cagcgtgtgc gcgccggcgt
    18721 ctcgcccttc cactcgccct tccactcgga cagcgtggcc ctgccacatc ggcgccatac
    18781 cgacggtgag atccgcgcac gctgcccgcc ggtggtgatc agcgcgttga ccggcgccag
    18841 ggggtcaccg gccatcgttt tggccagcac aacggcggcg gccagcggca gcaacgtcgc
    18901 ggcgagggcc gcgccggtgt tggcgacgtg ccgcatgttc acccgccggg atgcgtcaga
    18961 gatcatgctg ctcattccag cagcggcacg gccgggccac atccggtggc gtactcagtg
    19021 ttcctcctcc cgtactcagc cgccgagaaa cccgtccggc catcgccgtc tcccgatcgg
    19081 tcggacggtt cctggcagcc gaagaccggt ccctgcgccc tggggagggg gtcggcgagc
    19141 acgaccgcgt catcgcagtt cccgcgtccg ctggcatcag ggtgcggcgt tgccgacgag
    19201 cgccgccaac tcgccggccg actcggaggt caggcggtag aacccctgga ggctgatcga
    19261 gcgctcgagg cggccatctg ccgtcacgta cttcagaccg cgggtgtggc ctctccggtt
    19321 gcgccaggtg agtgtggcca gcagatcgcc cgggacgggc acatcgaagc gtacgggcgt
    19381 cgcgtccacg tgcaccgccg cggcaccgca gccgtcggca ccgagcatcg accagtcgcc
    19441 gtgcccgggg aacgccgggt cctgccacgt cgccggtgtg ttgccgcagc actggcgccg
    19501 ctccatgtcg gtgacccgca tccggctcac cacgtagacg acgcatcggt tgacatgcag
    19561 cgcgtacacc tcgtccccca cccgggcgcc cgaccaggcg ggcagggagg aatgcacgcc
    19621 actgaaggca acaggcggcc gctcgcccac gcgacccgcc ttgcgcaggg cacggcatgt
    19681 gtcatgggtc cacaggacag tgaaggcatc aggcatgccg taaccctacg aacgaggact
    19741 gacaaccacc gttggaccgg gtcatggagg aaccggctgg gtgggcctgc cccaccttgc
    19801 tcccgcgccg gcggaggtgc cggtatccgg cgggtcgtgt cggtcccggg ggtgcctggc
    19861 ggagagtgtc aggagggtgg ggacggtgat ttcgctcctg atgtgtcggg tgcgtccggc
    19921 cacgcggcca tcgccgcgtc gacgatgcga tccagtgtct cccgccccgc cccgtcgcag
    19981 gcctgctggt tcatcccctg gatgacggcc gcgtagaagg ccgccagccc gtcagcgtcg
    20041 atgtcggcgg gaagtcgccc ggcgtcgatg tcggtgcgga tgcaggcggc gatcgaggcc
    20101 ttcgtgtcct cgcgcatggc gcgcagcttg tccttcacgt cctgcgagcc aggggtgcag
    20161 ttggtcgccc ccgtgatgat gaggcagccc ggcgggtggc tcgcgtcggc gtagtcggcg
    20221 gcgaggtgcc gcagcatggc ggcgatggcc gaataggcgt ccggaccctg cggcggggga
    20281 gctccgtacg tgtgcacgta cagctggacg gcctcgtcga acagctgccg cttgtcgccg
    20341 aaggcggcgt acaggctcgg cgggttgatc cccatcgcct tggtgagcga ggcaaccgac
    20401 gtcgcatcga aaccgtgcgt ccagaactcc cgcagcgcgg cggccagggc ctgatcgcgg
    20461 tcgaaggagc gccggctccg cctgggcgcg gccttggccg cggcgcttct gctgctcatg
    20521 gccgcagtct atcgccaacc gtagcgatcg ctaaagaagt actgctacgg tcgtcgacat
    20581 cgcacagctt tagcgttcgc taaagctgag gcgagccgac catcatgccg cgaaagggaa
    20641 gctctgatga ccacgccgac acctgtcgcc ttcgcccgca ccgtccgcgg aagcggcccc
    20701 ggcctccttc tcgcccacgg ggcgggcggc ggcatcgagg ccaactacgg accgatcatg
    20761 gaagggctcg ccgcgaggca caccgttgtc ggggtggact accccggcag cggcgcgacc
    20821 ccgaagaacc agggggacct tgacgtcgac gagctggcgg agcagcttgt tgcagcggcc
    20881 gacgccgagg ggctcgacac cttcgctgtc agcggatact cactcggcgg gcctgtcgcg
    20941 atccgcctcg ccgcgcgtca cccggaacgc gtcacctcac tcctcctgag cgcgacgttc
    21001 gcgcacgccg acacccgcac cgacctcgcc gcctccatct ggcaccagct gttcgaagcc
    21061 ggccggcacg acgtgctcgc cgaatacctg aacctgatgg cactgggcga accggctctc
    21121 aacgccatga cccccgccca ggtttccggt gccgccgggc agctcgcgtc cgccctgccc
    21181 gccggcaccg cagagcaggt cgacctggtc cgaagggtcg acgtccgcgg cgaccttgcc
    21241 gacatccacg taccggcact cgtcgtcgtc accaccgccg acccgctcat atccccggcc
    21301 cttcagcggg aactcgcggc cgccatcccc accgccgagg tcgctgaact cccggccgga
    21361 cacctgccgt tcaccgaatg ccctgagcag tggctcaagc tcatcaccga cttcctcgca
    21421 cggcactgaa tatgcctcac cggtccggcg ctcggcctcc ggtgaccacg gggcgagccg
    21481 gcgtcacccc ggcgcccgtt gcggcggacc ggtgagacat gttggggggc cggcgcggca
    21541 acgttcctcg gcattcacgc cggccacgcc ggcttcgcca ccccggctgg agcgcttgcc
    21601 cccccgtact cagggagtcc ggggctgggc acgtcgccat tctccggaat ggccaggtgg
    21661 gagcgccagg tcacgtcgga cggccacgta gtagccctca cgtgcggcgc gttggcgctt
    21721 gagcaaggtc gaccaggttt ccgggcaatg agtccggtct cgcaggaacc cttccatctc
    21781 catcaccacg acgacccact cgcgggcttt ctccacgacg tccggggtgc cgagcatcaa
    21841 cagtgcctcc ccggctggat cccgggcatc agtggcatcg gccaggtgcg gcgccgcttc
    21901 ctcgggtgac aggggatgcg ggtgcggatc gttgccgagg tgcgccgcga cccggtatgc
    21961 cagggtgaca ctcttcttca gcgacctggc gtagtcggcg tacgccgtca tccgccgctc
    22021 ttcccattgg gccgcctgct cgcgacggaa gcgggcttga tcgccgcgcg tgctcgccaa
    22081 gtacgagccc agggcaccga tcaccacgcc gatcagggca gggagttgtt gtatgaacgc
    22141 tgacatggcc gcacggtata tcgccaggac aggcgcgact tgatggcatc tcaatcggtg
    22201 aacgcgatgc atggagcttt gccggccgtc agcggcgggg gtctcggcgg gaccggaacg
    22261 gcgggacgcc atgggcacat ggctcaaggc atcgccaaag gaaacgacgt cttaaggcgg
    22321 ttgatcgccc gtccgacggc aagcggtagt cacgtgatcg gccggacagg tcctacgctg
    22381 tccgcacgaa taccggcgtc aaggagtaga gcagtgcgga tagagcgtca tcaggtaagc
    22441 gaggcagtcg tatcggcggc gcgcgaggac ttcgcgaacc ggatcg
//
