LOCUS       NZ_LIYH01000005        22565 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold5, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000005
VERSION     NZ_LIYH01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 912609)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912609)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 571882
            Orig. end                         :: 594447
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22565
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22565
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22565
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12565](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12565)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            563..1099
                     /locus_tag="AMK26_RS23990"
                     /old_locus_tag="AMK26_23645"
     CDS             563..1099
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073836.1"
                     /locus_tag="AMK26_RS23990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23645"
                     /product="flavoprotein"
                     /protein_id="WP_073756774.1"
                     /sec_met_domain="Flavoprotein (E-value: 5.3e-09, bitscore:
                     31.8, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQPKKPFLYVVVCAAGIADDVAKLITAAQERHWDVGVVATPQG
                     LGFIDVAAVQAQTGYPIRSAWRSPDDPRPLPPANAIAVAPATFNTINKWAAGISDTLAL
                     GILCEAYGFGIPTAVLPYLNAAQAAHPAYRQSLDRLREMGVLIGEYEPHQPKAGGGRDK
                     FRWEQALELLEPKVR"
     gene            1907..3496
                     /locus_tag="AMK26_RS23995"
                     /old_locus_tag="AMK26_23650"
     CDS             1907..3496
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (99-285). E-value:
                     2.7e-22. Score: 71.5. Matches aSDomain:
                     nrpspksdomains_AMK26_RS23995_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062673.1"
                     /locus_tag="AMK26_RS23995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23650"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_241838038.1"
                     /sec_met_domain="PF00561 (E-value: 2e-41, bitscore: 138.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTHGKRHRRAVVLAVAATLAAGSLSGCTQGAPDAAADPAARADL
                     RVFYHQKPQWKPCGEEECATLKVPMDYSAAGNGKTFTLPLVRATATDTARRIGSLVFNP
                     GGPGESGVALLKDGGAESFSEQIRARFDIVGFDPRGVAGSKPAVDCGPDEEGGADTQAG
                     DVSPQPLHPATAEQRRAALADAESAVAACKRYSGSILPHVGTADAARDMDVLRAALGED
                     KLSYLGWSYGTSLGTTYGELFPWRVRAMVLDGAVDPSLDWSERALSQAAGFRKAVDDYA
                     EHCADVVGDACPADTPEGIRELLDGLYEQTAKEPLPVDDSDGGLDAATLHSAIVTSMYT
                     PEEQWKPLSHGLSDAAGGDGTRLAGIAAGEEDASEDEDTGSDDEEEQGEKSHPDNSDVA
                     ITAVDCVDIPHPRDSQKYWQALDQAHRAEGDYGSESVVAALGCKGWPHRGPGPHRVSAD
                     GLPPVLVVGTTGDPSTPYHEAESLARQLPQGMLLTFEGLGHTAYGRGGSCVDTAVDSYL
                     IDLKPVKPGATC"
     aSDomain        2204..2761
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS23995_Abhydrolase_1.1"
                     /evalue="2.70E-22"
                     /label="AMK26_RS23995_Abhydrolase_1.1"
                     /locus_tag="AMK26_RS23995"
                     /protein_end="285"
                     /protein_start="99"
                     /score="71.5"
                     /tool="antismash"
                     /translation="LVFNPGGPGESGVALLKDGGAESFSEQIRARFDIVGFDPRGVAGS
                     KPAVDCGPDEEGGADTQAGDVSPQPLHPATAEQRRAALADAESAVAACKRYSGSILPHV
                     GTADAARDMDVLRAALGEDKLSYLGWSYGTSLGTTYGELFPWRVRAMVLDGAVDPSLDW
                     SERALSQAAGFRKAVDDYAEHCA"
     gene            complement(3923..4159)
                     /locus_tag="AMK26_RS35830"
                     /old_locus_tag="AMK26_23655"
     CDS             complement(3923..4159)
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012383.4"
                     /locus_tag="AMK26_RS35830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23655"
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="WP_073756775.1"
                     /transl_table=11
                     /translation="MRADVFAYGIVPGQRIVLVDDEITTGRTLADLTRRLREAGTVPLA
                     AACLVEDTTRGGRALLADLGVPLVSLTTIEGQT"
     gene            <4255..4942
                     /locus_tag="AMK26_RS24005"
                     /old_locus_tag="AMK26_23660"
                     /pseudo=""
     CDS             <4255..4942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047316.1"
                     /locus_tag="AMK26_RS24005"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AMK26_23660"
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RLELGRRATELRAYDDHVTVTLDAGTHLTAQYVIVATGVGALQPG
                     DVPWITAPSGLTLPPLWQAEQDDAEGRTLLILGGDRPIGTFLRAHEATDTRLLVVYPES
                     DDYKVEEIYNDPRVTLLSMEHLTLHAAEGTATTAEVLGRGGERQTITAGRRLPQHRQRF
                     CRPCRRRHPQCDRLLPPVGTAPRVIVAGDLRSARFQRIMTAMGFGQRSRLARLLRRLGS
                     VRAWWGM"
     gene            complement(5351..5749)
                     /locus_tag="AMK26_RS24010"
                     /old_locus_tag="AMK26_23665"
     CDS             complement(5351..5749)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="AMK26_RS24010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23665"
                     /product="ATP-binding protein"
                     /protein_id="WP_073756776.1"
                     /transl_table=11
                     /translation="MVQPPEAQHPDPSGRRHIRTAGQARDVTRGFLSSVGPSDNAEAEA
                     VVLAVSELVTNAERHAGGVTGFRLDAAPGSVTVTVSDASTTPPRFRRTDAFEPGGFGWP
                     LVQELATKVSVTIHPHGKSVRAVLPLAH"
     misc_feature    5888..5902
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            complement(5982..7385)
                     /locus_tag="AMK26_RS36365"
     CDS             complement(5982..7385)
                     /GO_function="GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012862.4"
                     /locus_tag="AMK26_RS36365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="caspase family protein"
                     /protein_id="WP_338015593.1"
                     /transl_table=11
                     /translation="MSQESAGSVSYPKRSRAVLFGCHAYRHLDGIPAVQNNLAALHEML
                     LDPKWGKPGMDVTSLSPWAGADEILETVATAGEQAQDTLIVYFAGHGLIHPKNGELYLA
                     LHNSRLQRWGVAAGLPISDLRHAILDHENTADNKVLLLDCCFSGRAMAGGMGPAGPENK
                     ADLAAIEGTCVTTSSSSTSLSFAVPGDRYTGFSGALIEVLESGAPGEGPMLTMEAVYRQ
                     VDARLRARGLPRPQQRNSNLAGHIPIARNRAWIPSAGEQAPPPGPAPRTVPARRSRVQS
                     LRIHWRRYRNRYAAALFAIVIMTIAVASSVLPAGTPDRGTPAPFPPKRQDAGLLQSASN
                     KGKDCVRHIGDPPLGSAPIGACDAAQVDWSMWTFPNDHVRFISQRIPGVCLGADIHAPA
                     KPVGTWGCDDPASAWVLQPQTDGSFHLVNEQALDNGLKKRCAARHDTAIYLDECRDDTN
                     HAWLVPQSH"
     misc_feature    complement(6384..6386)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6705..6707)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7388..7747)
                     /locus_tag="AMK26_RS37080"
                     /old_locus_tag="AMK26_23675"
     CDS             complement(7388..7747)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040404.3"
                     /locus_tag="AMK26_RS37080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23675"
                     /product="hypothetical protein"
                     /protein_id="WP_073756778.1"
                     /transl_table=11
                     /translation="MRLTLAVHEGSNRQEADALRVWLTQEQMLRGQVRIPVDSVPLPGA
                     MGQPLELVSVLLSNTIALGNLLVAVAAWRQSRPRQPSVRIEVNGRSFILDTSNPGELEA
                     LARALREADGSATDG"
     gene            complement(8160..10004)
                     /locus_tag="AMK26_RS24025"
                     /old_locus_tag="AMK26_23680"
     CDS             complement(8160..10004)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987088.1"
                     /locus_tag="AMK26_RS24025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23680"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073756779.1"
                     /transl_table=11
                     /translation="MTAAPAQVPDRSTRAAVATMYRLTTGHRASVVVATVLTLVGSALG
                     LAQPLVAKQIVDVSGDGRVFWPLLLLLAVLFVTEAATGAVGRFVLERMGEGVVRQLRHG
                     LVGRLLRLEMREYDRHRSGDLISRVTADTTLLREVVSQALVDLVTGALVAAGAVALMLW
                     IDPLLLLLVALTVAAAAAVVASLLKGIRAASEQMQNSVGAIAADLERALGALPMVRVHR
                     AEDREARRIGERIESAHDAGVRTAKLASVMSPAVELAVQGSFLLVLVIGGLRVTGHATS
                     LGDLVAFLLYASYLVLPLSSVFRAVGLIQRGMGAYQRIEHALALPVEPSQAQMPAVRAR
                     TREPARQAAAYEEPALALRDLTFGYDPDRPVLRGVTLTVPHRRQTALVGRSGAGKSTIF
                     ALVARFYEPDSGALLFDGRPAGELTRAECRERIAIVDQNTHVVHGTLRDNITYAVPDAP
                     EAEVRRVVELAQLDDVVRRLPGGLSGLLGERGSTLSGGERQRIALARALLGRPELLLLD
                     EPTSHLDAINETALTKVMKDIAGECALLVIAHRLSTVQHADQIVVLENGRTTACGRHEE
                     LLTCSPTYRELAAGQMLRPATPHPSPMTTARSHPHNQL"
     gene            complement(10001..10444)
                     /locus_tag="AMK26_RS24030"
                     /old_locus_tag="AMK26_23685"
     CDS             complement(10001..10444)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602541.1"
                     /locus_tag="AMK26_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23685"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_073756780.1"
                     /sec_met_domain="PF13471 (E-value: 8.5e-24, bitscore: 79.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALERPTGVPLTRRLAARLVLLPAVVLSLLPPRRIRAVLGA
                     VRRGAAPATAAQAQSARDAMCAVSLLCAGPKGCLPRSLGAALLCRLTGSWPTWCTGASV
                     VPPFNAHAWIEAEGRPIGEGVPDDYFRRLLAVGPVTANRPSRP"
     gene            complement(10441..10695)
                     /locus_tag="AMK26_RS24035"
                     /old_locus_tag="AMK26_23690"
     CDS             complement(10441..10695)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309239.1"
                     /locus_tag="AMK26_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23690"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_073756781.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 8.7e-08,
                     bitscore: 27.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-26,
                     bitscore: 88.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5e-17, bitscore: 57.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALRFGPDVSAAETDYGTVLLDQRSGNYWELNPTGTLVVKTLLEG
                     GDEAAAVDALVTEFDIDRARAEPDVTALVQELRTSGLAS"
     aSDomain        complement(10447..10692)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AMK26_RS24035_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.30E-28"
                     /identifier="RREFam002.1"
                     /label="AMK26_RS24035"
                     /locus_tag="AMK26_RS24035"
                     /protein_end="83"
                     /protein_start="1"
                     /score="88.5"
                     /tool="antismash"
                     /translation="ALRFGPDVSAAETDYGTVLLDQRSGNYWELNPTGTLVVKTLLEGG
                     DEAAAVDALVTEFDIDRARAEPDVTALVQELRTSGLA"
     gene            complement(10727..12565)
                     /locus_tag="AMK26_RS24040"
                     /old_locus_tag="AMK26_23695"
     CDS             complement(10727..12565)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057605464.1"
                     /locus_tag="AMK26_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23695"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_073756782.1"
                     /sec_met_domain="Asn_synthase (E-value: 2e-48, bitscore:
                     161.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELHASAGTGPGDAHFAVFTDREDAAAVARSFALPGTRTLRHAS
                     GRPWLVGHWDDQELVTAHTGRAALAIIGCCPIDAAGLKRHAERLRDLAELDALARSLPG
                     SFHLVATLDGRLRVQGTASGLRLVFHAAVDGVQVAATRADVLADALGTAPDEQQLAVRL
                     LWPVPYPLFEAPLWREVTAVPPHDALVIGADGHSARHSRWWTPPEPVRTLADGAPLVRE
                     ALTEAVGARTRQGGVVSCDLSGGLDSTSICFLADRSPARVVASTWPGRDPADTDLYWAG
                     QAAKHLPHVEHVVWDADASPLVYDDLLSIDDLLDEPTIGVMDRSRVLHHLPGMAERGSR
                     LHLTGIGGDHVAWCSEAYYHRLLRTRPLFAMRQLRGFRALWQWPLGSTVRALADSRPYG
                     KWLADRSGRLRDPVPATVTTSLGWGMPPRLFDWVTPDAERLAQRALREAAATVTPLHPD
                     RGLHTDLEQIRSCTRIIRQWDRMAARAGVPMASPFLDDRVIEASLAVRPSERVSPWQYK
                     PLLTAAMRGIVPDGCLRRTTKAAASMDAADGLRRHRGDLLTLWEDSRLEQLGLVDGNAL
                     RRLAQRPSTPALRDAILYSTIAAEVWLRGLSAARTR"
     gene            complement(12592..12702)
                     /locus_tag="AMK26_RS36370"
     CDS             complement(12592..12702)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656044.1"
                     /locus_tag="AMK26_RS36370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_107050258.1"
                     /transl_table=11
                     /translation="MKKAYEAPTLVRLGTFRKKTGLLQSSGNDRLILSKN"
     misc_feature    complement(13468..13483)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.85"
                     /tool="antismash"
     gene            complement(13785..14222)
                     /locus_tag="AMK26_RS24050"
                     /old_locus_tag="AMK26_23705"
     CDS             complement(13785..14222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540726.1"
                     /locus_tag="AMK26_RS24050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23705"
                     /product="hypothetical protein"
                     /protein_id="WP_073756784.1"
                     /transl_table=11
                     /translation="MAEITKVNVQLITATESEANVGGWVYVSIAGREFSLDADHNDFEP
                     GDNFTYTFGEGSNVLYADRNDPRFPALDTDDLDRYPVYLRYEPPGSEPNESWCLERVIV
                     TVNPGGEFTARYDNLRLAGSAANQKIWLGQRYGKAVNLRRV"
     gene            14519..14911
                     /locus_tag="AMK26_RS24055"
                     /old_locus_tag="AMK26_23710"
     CDS             14519..14911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944602.1"
                     /locus_tag="AMK26_RS24055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23710"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_073756785.1"
                     /transl_table=11
                     /translation="MDRTVEALLDQVQVRGGYAGRQEAVRAVQSVLDVLGAHLVGDDRT
                     DLARLLPRQCAPLLTDGAPASEPLTPSGFIDAVAARDEMDAAAARRAVTAVLATLAEVA
                     DDVLLRRILTQLPPGHAGLFGRTDPA"
     gene            complement(14987..15412)
                     /locus_tag="AMK26_RS24060"
                     /old_locus_tag="AMK26_23715"
     CDS             complement(14987..15412)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575808.1"
                     /locus_tag="AMK26_RS24060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23715"
                     /product="DUF6003 family protein"
                     /protein_id="WP_073757091.1"
                     /transl_table=11
                     /translation="MADDAHLFLLPDRHPLLGAALAAVGPLECAETPAVRGWLQAHAVS
                     AASEQVRILPAGSEVLIPEDAEHLPVPLSEDEALRVQQECAPQSVTDVEAELLDFRETT
                     QDWEALVHRALTAGIPAPRIAQLTGLPPQEIGRLTQA"
     gene            complement(15468..15794)
                     /locus_tag="AMK26_RS38025"
                     /old_locus_tag="AMK26_23720"
     CDS             complement(15468..15794)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS38025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_23720"
                     /product="hypothetical protein"
                     /protein_id="WP_241838041.1"
                     /transl_table=11
                     /translation="MGRELPMDVRTQFNDELVRGHDSLPAKDQAVVVALPQEYGEHLAL
                     LLSGGKQEAPQGCCPSLHHVFGGSEKSHRVRLPDSLADRLAHEGALGAGAEVVFSMAVE
                     SVWP"
     gene            complement(16022..16864)
                     /locus_tag="AMK26_RS24070"
                     /old_locus_tag="AMK26_23725"
                     /pseudo=""
     CDS             complement(16022..16864)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389541.1"
                     /locus_tag="AMK26_RS24070"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23725"
                     /product="RNA polymerase sigma factor SigF"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTATKTSSDRSQVDTPLVEDPGGLAPQDARTLSKHFFDQLASLE
                     RGHRSISTRATR"
     gene            complement(16915..17250)
                     /locus_tag="AMK26_RS24075"
                     /old_locus_tag="AMK26_23730"
     CDS             complement(16915..17250)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639072.1"
                     /locus_tag="AMK26_RS24075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23730"
                     /product="hypothetical protein"
                     /protein_id="WP_073757093.1"
                     /transl_table=11
                     /translation="MVPVNGEIEREALVARLWQEHLDAPFPARLRGAELEGIDMVMLDA
                     DIAGCVSTWRDNGGSLDAWRYQVLRDCISELDKILPHLMEAEDLRYYERLHQLATLTSQ
                     TAPRLNK"
     gene            complement(17281..18077)
                     /locus_tag="AMK26_RS36380"
     CDS             complement(join(17281..17735,17735..18077))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948682.1"
                     /locus_tag="AMK26_RS36380"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_241838067.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MVERLVPDGLWELFQRVVPAAPVRPQGGGRQRYGDRQVLAAILFV
                     ATSGCTWRQVPPGFGPSGPTAHRRFTEWSRARVWGKLHRLVLDELGARGELDWSRCAID
                     SVNMRAMKGGNLTGPNPVDRGKKGSKIHLITERTGLPLSIGISAANTHDSQGLEPLVRG
                     IPPIRSRRGPRRRRPAKLHGDKGYDYDHLRKWLRTRHIVPRIARRGVESSARLGRHRWT
                     VERTVSWLGGCRRLHRRYERKAEHFLAFTGIAAALICYRRLPT"
     misc_feature    complement(18048..18050)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18562..18575)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            18562..19065
                     /locus_tag="AMK26_RS37085"
     CDS             18562..19065
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS37085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158071145.1"
                     /transl_table=11
                     /translation="MIWTSMDGYQVDADRAALDIRMGGGQEKVTQFRWFINGTVAPHAA
                     AHSSDRSSDSRDDFPVSRSAGQYSLRTSGLPDIGLGQCQSLREFGQFQLSGLYGATGAI
                     FSEDTDPRGANPCTVGEGLRVQVRASHRTLQQLGKVSHDLYLPGVGRRSLPHSGDSASL
                     RKKL"
     misc_feature    19048..19050
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19347..19685
                     /locus_tag="AMK26_RS24095"
                     /old_locus_tag="AMK26_23750"
     CDS             19347..19685
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="AMK26_RS24095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23750"
                     /product="ATP-binding protein"
                     /protein_id="WP_073756787.1"
                     /transl_table=11
                     /translation="MRRAAGLFLGSLAHQDPPTDSESWGDILLVVTELAANAIQYAPGP
                     FTLRIRRAFDGVHVAVGDHNPSPPAPRPCDPARGAGGLGWHLIQALSRQVSIVPHEGGK
                     EVHAFLPW"
     misc_feature    19706..19721
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.4"
                     /tool="antismash"
     gene            19830..20171
                     /locus_tag="AMK26_RS36775"
     CDS             19830..20171
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS36775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143608617.1"
                     /transl_table=11
                     /translation="MAANMHSDERRVGVRSYAEVDVALNGLVVRRKSAPRFSAGAAAAY
                     EWAMGQTVRSPVTGAEVHGIPDLGLLTAEVDAAVIQLEDPTTPVGNRDYTRGAHDALAW
                     VCGYSDQLP"
     misc_feature    complement(19836..19851)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.27"
                     /tool="antismash"
     misc_feature    19837..19850
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.11"
                     /tool="antismash"
     gene            complement(20710..22410)
                     /locus_tag="AMK26_RS24105"
                     /old_locus_tag="AMK26_23755"
     CDS             complement(20710..22410)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321540.1"
                     /locus_tag="AMK26_RS24105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_23755"
                     /product="mobilization protein"
                     /protein_id="WP_073756788.1"
                     /transl_table=11
                     /translation="MIAKISSGKDTAGLIRYLYGPGRANEHTDPHLVASFDGYAPDPGR
                     ADDPAATKKLLVADLDLHVKQARRHGRAPERHVWHCSIRAAETDRHLSDSEWADIARRV
                     VAATGIAPDGDPDACRWVAVRHADDHIHIAATKVRGDLRPARHWNDYLTADKELVAIEK
                     EYGLQQVVRGDRTAAKRPTRAEKEKAQRAGHAMTARERLRFTVRTAVSVATSPEEFLGI
                     LAATDSVLVEIQRFPSGDIRGYKIAIEGDTNAVGEPVWYSGSRLAPDLSFPQIRDRLTA
                     ADQLTQTQQHRPDPWHQATAAAEHIPHHLDQSDDAAAQAHIAAFGQALDALPLLTLKEI
                     RPQLRQAAAAFERATRSRIRAEHEHARALRGAIRALRTQPAPRDGAMLAMFLDVAILAV
                     IAAGRWHQLRQHDQQVIAARQALVHLQAAYDQAAAVPLATLDHRKPSAPTVERLAALVY
                     EAVPTHAQRVLDDHAWAALATALSDAEAAGHEPTTLLKQAVDQRPLDDTRSPARALIWR
                     VSRLVQLPTSSSRAAQARTVTDTRTVRPIQTESLPPHQPSAPGMQGRGR"
ORIGIN
        1 agaagcacac cggccaggca atcacgctcg tccggcacac cgccgaccag ctcaccgggg
       61 cctacgacca acgatcaccg cgatacctcg cggcgctcgg gcttctgttg ctgcgtggcg
      121 tcaccgctgc cagcagcggg ggcaacagga cggcgagcca ggagttcctg gcggaggcga
      181 aggaggtcgc gcgcttcgtg gccctggacc gtccggacgc ctgggcgaac ttcagcctca
      241 ccaacgtggc gctccacgag gtgagcgccg ccgtcgcctt cggagacgcg ggaatcgccc
      301 tccaggccgc ccgccctctc atgcgccggc acatcccagt gcccgagcgg cgcgcggcac
      361 tgtgggtgga gaccgcgcgc gcctacagcc agcagggccg gctcgccgac ggttaccagg
      421 cgctgcgcat cgccgagagc tgcgctgccc aggacatccg tcgcccggcc gtccgcgaat
      481 tggtcgccga catggccgcc cgcgaccgcc gtcgtacgct tccagagctg caccacttca
      541 gtcgccaact gggggtcccc gcgtgagtga tcagccgaag aagcccttcc tgtacgtcgt
      601 cgtctgcgcg gccggtatcg ccgatgacgt ggcgaagctg atcaccgcag cgcaggagcg
      661 gcactgggat gtcggcgtgg tcgccacccc ccagggcctc ggcttcatcg acgtggccgc
      721 cgtccaggcc cagaccgggt acccgatccg ctcggcgtgg cgctcacccg acgaccctcg
      781 gccactgccg cctgccaacg cgatcgccgt ggccccggcc accttcaaca ccatcaacaa
      841 gtgggccgcc gggatctccg acaccctcgc gctgggcatt ctgtgcgagg cgtacggctt
      901 cggcatcccg accgccgtcc tgccctacct gaacgcagcc caggccgccc accccgcgta
      961 ccggcagagc ctggaccggc tacgcgagat gggcgtcctg atcggggagt acgaacccca
     1021 ccagcccaag gcgggcggcg ggcgtgacaa gttccgatgg gagcaggccc tcgaactgct
     1081 cgaacccaag gtgcgatgac gccacttcgt tacgccgctc gtcgacaacc agggcacagc
     1141 cgtacagctt catccagaga tcctgctcca gaccggacgc tgccttcgcg agaaccgagt
     1201 gcgcgaactg ctcctcctgg ctcgtcagac aggccgcact gcccatggga ccgacggact
     1261 ccaagacacg ccggaaggac tggtggggga ggttccgaga caggccgaac agcaactccg
     1321 ccgtgtcctc caagccctgg ggccagtggg acagctccgc gccgaatgcc tcgacaagcc
     1381 cccgggtcac ctcatacgca taccggcctg gccggtcgaa aacattggtc aaaaggccat
     1441 ggcgaagacc tatcggctcg gcggggcctc ggcgagccac cacgcgctcc gggcggcgac
     1501 ggccccgtga ttcacacgga tggcgaaccg gtcctgggcg gcctgcatcc gccgctcgtg
     1561 gtgtgcgcgg tacaagacgc gcggtcgagg gatgatggcc ctcgcaccac gctggctttc
     1621 ttggggctgc ccccggcctg tcatccactg ccctccggtc ccggtcatcg gggcttggca
     1681 ccacaggttc ggccgcaggc cagtgggcgg cgagggcggg gcggatcggc tcagtggcga
     1741 aaggccgggt gagcttttcg gcggcgcatt ggttgtcatg cctccggacg aaaaggggaa
     1801 aggcggcctc tacctgagaa cgatgtgggt ctgggattct gctcgtaccg tgtcctcgac
     1861 gctgacacgc cgcagcgatg ctcactctga cctcggagca cctcccttgt tcactcatgg
     1921 caagcggcac cgccgtgccg tcgtcctggc cgtggcggcg accctcgccg ccggttcgct
     1981 gagcggctgt actcagggcg cccccgatgc cgccgccgat ccggctgccc gcgctgatct
     2041 gcgcgtcttc taccaccaga agccgcagtg gaagccctgc ggcgaggagg agtgcgccac
     2101 gctgaaggtc cccatggact actcggcggc cggcaacggc aagaccttca ccctccccct
     2161 ggtaagggcc accgcgactg acacggcccg ccgcatcgga tcgctggtct tcaacccagg
     2221 cggccccgga gaatccgggg tcgccctgct caaggacggc ggagcagagt cgttcagtga
     2281 gcaaatacgg gcccgcttcg acatcgtcgg gttcgacccg cgcggcgtgg ccggcagcaa
     2341 gcccgccgtc gactgcggcc ctgacgaaga gggaggggct gatacgcagg ccggtgacgt
     2401 ctcaccgcag ccgctccacc ccgcgacggc tgagcagcgc cgggccgccc tggccgacgc
     2461 cgagagcgcg gtcgcggcct gcaagaggta cagcggctcg atcctgccgc acgtcggaac
     2521 agctgacgcc gcacgcgaca tggacgtgct gcgcgccgcg ctcggcgagg acaagctgag
     2581 ctatctcggc tggtcctacg gcacgtctct gggcaccacc tatggcgagc tgttcccctg
     2641 gagggtacgc gcgatggtgc tggacggggc agtcgacccc tcgctggact ggtccgagcg
     2701 ggccctcagc caggccgccg gattccgcaa ggcggtcgac gactacgccg agcactgcgc
     2761 cgacgtggta ggagacgcct gccccgccga cacccctgaa ggcatccgcg agctccttga
     2821 cggtctctac gagcagaccg ccaaggagcc gctgccggtc gacgacagcg acgggggcct
     2881 ggacgcggcg accctgcaca gcgccatcgt cacgtcgatg tacacccccg aagagcagtg
     2941 gaagccgctg tcccacggcc tgagcgacgc ggccggcggt gacggaacgc ggctcgccgg
     3001 catcgccgcg ggagaggaag acgcctcaga ggacgaggac accggcagcg atgacgagga
     3061 ggaacagggg gagaaaagcc acccggacaa ctccgacgtg gccatcacag cggtcgactg
     3121 cgtcgacatt ccccacccga gggactccca gaagtattgg caagccctcg accaggcaca
     3181 ccgcgccgag ggcgactacg ggtccgagag cgtggtcgcc gcgctcggct gcaagggctg
     3241 gccgcatcgc gggcccggcc cgcaccgggt cagtgccgat ggtcttccgc cggtcctcgt
     3301 ggtaggcacc accggcgacc cctccacgcc ctatcacgag gccgagagcc tggcccggca
     3361 gctaccccag ggcatgctgt tgacgttcga gggactcgga cacactgcgt acgggcgcgg
     3421 cggtagctgc gtggataccg ccgtggacag ttacctcatc gacctcaagc cggtgaagcc
     3481 gggcgcgacc tgctgacgcc gcgggacacc gccgcactcc gcctgcctgg ggcgcgcacg
     3541 cccccactcc ctgcaatgcc ggcgtgagct gtgcaccgat cgaccggcag cggccgatgc
     3601 ggactcctgg ccggcccccg gcatgtgaac cagcgcgacc gtcgcccaag gcccgcagcc
     3661 tcatgtgcag ctgacccgtg cggtgaagcc ccacggacgg ctgacagggc gagcagggtg
     3721 tctccgagct tccccgcgaa ggccacctcc atctcgccgc aggtgttcag agggtcgacg
     3781 agttctgtgg aggcgggtat ggggagcggt gtgccgacgg gaaggtcgat gcggtcataa
     3841 ccaagtggtg tggtgtgtat ggctccggcg gggtggatct gcgtgccggg atggaaacgg
     3901 ttccccgccg aggcgagtgt gctcatgtct gtccctcgat ggtggtgagg gagaccagcg
     3961 ggactccgag gtcggcgagc agcgcgcggc caccgcgcgt ggtgtcctcc acgaggcagg
     4021 cagccgctag cgggacggtg ccggcctctc ggagccgacg ggtgaggtcg gccagtgtcc
     4081 tgccggtggt gatctcgtcg tccaccagga cgatccgctg tccggggacg atgccgtagg
     4141 cgaagacgtc ggcgcgcatg gcgcggggtt cgctgaagcg gaccgcgccg tcgaggggga
     4201 ggtgcagttt ccaggcgatc ttgtacggca gcctggcggc gccggcgcgg gagacgcctc
     4261 gaactcggcc gccgcgctac ggaactccgc gcctacgatg accacgtcac cgtcacgctc
     4321 gacgccggca cccacctgac cgctcagtac gtgatcgtcg ccacgggtgt cggggctcta
     4381 cagccagggg acgttccctg gatcactgcc ccctccggtc ttactctccc cccgttgtgg
     4441 caggcagaac aggacgacgc cgaaggccgc accctcctca tcctcggcgg cgaccgcccg
     4501 atcggcacct tcctacgcgc ccacgaggcc accgacaccc gtctgctcgt ggtgtacccg
     4561 gaaagcgacg actacaaggt cgaggagatc tacaacgacc cccgcgtcac cctcctctcg
     4621 atggagcacc tgaccctgca tgcggcggaa ggcacggcga cgacggccga agtgctgggc
     4681 cggggcggcg aacggcagac catcacggcc ggacggcgtc ttcctcagca tcgacaacgc
     4741 ttctgccgcc cctgccggcg gcgtcatccg caatgcgacc ggctactgcc tcccgtcgga
     4801 acagcacccc gggtcatcgt cgccggcgac cttcgctccg cccgcttcca gcggatcatg
     4861 acggccatgg gcttcgggca gcgaagccgc cttgcacgcc tactacgccg cttggggtct
     4921 gtccgtgcct ggtggggcat gagaacctgc gtgcccccgt ggcgcgaggc catcagcctc
     4981 caccagactg actaacacgg ggtcccaaaa gccgccctcg agatgaccac cagcgccccg
     5041 agcccatccg tcacccgccc acgtggcggc ccttgtgcgg cagacgcgag atgctgaacc
     5101 accagcgtct gcaacgcact ggggccggca cccgacaagg ttgatcaccg accccagccg
     5161 ggcggacgct accgcttctg caccgctgct gtgtgacggc tcaccggtcg tggcggaccc
     5221 gagacaggct tccagcgcag cccatgacag gacacgcgga ggcgtgcagg tgcggggttg
     5281 cggagcaatg gcaagccgac gcggccaaaa cagcgggctg tgatgtccac actggtcccg
     5341 cctcctgtgg tcagtgcgcc agcggaagca cggctcggac tgatttgccg tgtgggtgga
     5401 tggtgacgct cacctttgta gccagctcct ggacgagggg ccagccgaac ccgccgggtt
     5461 cgaaggcgtc ggtgcgccgg aagcgtggcg gggttgtgct ggcatcggag acggtcacgg
     5521 tgacgctgcc gggtgcggcg tccagccgga atcctgtgac gccgcctgca tgccgttccg
     5581 cgttggtcac cagctcggac acagccaaaa ccacggcttc cgcttcggcg ttgtcggaag
     5641 ggcccacgga ggacaggaag cctcgcgtga catctcgtgc ctgtccggct gtgcggatat
     5701 gcctcctgcc ggaggggtcg gggtgttgtg cctcgggtgg ctgcaccatc gcttcctccg
     5761 ggcgctgtct gacagttcct gggtcagacg tatgcccgga atgtaggcag cgagtcgtct
     5821 cggccggtcg aatacgggct ctggctcaca ttccgcgcca gacccacgga gggggaccac
     5881 tcccgcgatc acgagttgcg atccgggccg cgttgttgtg gccacgaccg gcccggaggt
     5941 gaagggcgcc atccgcatcg tccgcaggac ccggcattcg atcagtgact ttgtgggacg
     6001 agccatgcat ggttggtgtc atctctgcat tcgtcgagat aaatggcagt gtcatggcga
     6061 gcagcgcacc tcttcttcaa gccattgtcg agagcttgct cgttcaccag atggaaggac
     6121 ccgtctgtct gtggctgcag tacccaggcg gaggcggggt cgtcgcagcc ccaggtgccg
     6181 acgggcttgg cgggcgcgtg aatgtctgcc cctagacaca ccccgggtat gcgctggctg
     6241 ataaaccgca catggtcgtt ggggaaggtc cacatcgacc agtccacctg tgccgcgtcg
     6301 catgccccga tgggcgcgct ccctagcggc gggtcaccga tatgtcggac gcagtccttt
     6361 cccttgttgg aagcgctttg gagtaatcca gcgtcttgtc gcttgggcgg gaaaggcgca
     6421 ggtgtgccgc gatcaggagt accagcagga agaacggaag acgctacggc tatggtcatg
     6481 atgacgatgg cgaaaagggc tgcggcgtat ctgttccggt accgacgcca gtggatgcgc
     6541 aagctctgga cgcggctgcg ccgggccggg acggtccgcg gcgccggccc gggtggaggc
     6601 gcttgttctc cggcggacgg gatccaagcg cggttgcggg cgatcgggat gtggccggcc
     6661 agattgctgt tgcgctgctg ggggcgaggc agtcctctgg cccgtaatcg ggcatcgacc
     6721 tgccggtaga cggcctccat ggtaagcatc gggccttcac ccggcgcgcc ggactccagc
     6781 acctcgatca acgcgccgga aaacccggtg taccggtctc ctggcacggc gaaggagagg
     6841 gacgtgctgg acgaggacgt ggtgacgcag gttccctcga tcgccgcgag gtcggccttg
     6901 ttctccggac cagcggggcc catgccacct gccatagcgc gcccgctgaa gcagcaatcg
     6961 aggagcagta ctttgttgtc ggcagtgttc tcgtggtcga ggatggcgtg tctgaggtcg
     7021 ctgatcggga ggccagcggc tacgccccag cgctgcaggc gcgaattgtg cagtgcaaga
     7081 tagagctccc cgtttttcgg atggatcagg ccatggcctg cgaagtagac gatgagcgtg
     7141 tcttgcgcct gctcgcctgc ggttgccacc gtttcaagga tttcgtcggc gccggcccac
     7201 gggctcaatg aagtgacgtc catgccgggc ttgccccact tggggtcgag cagcatttca
     7261 tgcaaggccg ccaggttgtt ctgcacagcg gggatgccgt ccaggtggcg gtaggcatgg
     7321 catccgaaga gcactgctcg tgaccttttc gggtacgaga cgctaccggc ggattcctgg
     7381 ctcaccttca gccgtccgta gcggacccgt cggcctcgcg cagcgcgcgg gcaagtgctt
     7441 ccaattcgcc gggattgctc gtatcgagta tgaacgagcg gccattgacc tcgatgcgta
     7501 cggaaggctg ccggggtcgc gactgccgcc aggctgctac cgccaccagc agattgccca
     7561 gggctatggt gttcgacagg aggacgctga ccagttcgag cggctggccc atggccccag
     7621 gcaggggaac gctgtctacg ggtatccgca cctggccacg cagcatctgc tcctgcgtga
     7681 gccagacgcg cagcgcgtct gcctcctgcc tgttgctgcc ctcgtggact gccaacgtca
     7741 gacgcatatg tcctccggcc cttcaccgcc cggctgcgat cagggcatgg gccaactgtc
     7801 catgcctact ggcactgtaa ggcggtcccc agcgggctgt gacctctttg ctgaccacga
     7861 tcgtggggcc ggtcacatcg gtgtacgagc ctgggatccg cgttcacgct ccgcagacct
     7921 ggaatgggag ccagagccac aattcagccg gcgcccacga gtcgctgtgc gggttggctg
     7981 ccggacgaga gcggtcaagg tccccggttc acgagggtgg tcaggtcgag gccgctcatg
     8041 tgccgcttcc gggtaatgcc ctcggcggag cgcggcccgg cggcatcgga ctcggcggcg
     8101 acacctcgta tggggtgcct tcgcagtccg tccgcgatca ccgttgtgtc cgctccggct
     8161 tatagctggt tgtgcgggtg tgaccgagcg gtcgtcatag gggaggggtg tggggtggcc
     8221 gggcggagca tctgcccggc cgccagttcg cggtaggtgg ggctgcaggt gagcagttcc
     8281 tcgtggcggc cgcaggcggt ggttcggccg ttttccagta cgacgatctg gtcggcgtgc
     8341 tggacggtgg agaggcggtg cgcgatcacc agcagggcgc attcccccgc gatgtccttc
     8401 atcaccttgg tgagcgcggt ttcgttgatg gcgtcgaggt gggacgtggg ctcgtcgagc
     8461 agcaggagtt cggggcggcc cagcagggcg cgggccaggg cgatgcgctg gcgctcacct
     8521 cccgagaggg tgctgccgcg ctcgccgagc agaccggaca ggccgccggg cagtcggcgt
     8581 acgacatcgt cgagctgggc gagttcgacg acgcgccgta cttcggcctc cggggcgtcc
     8641 ggtacggcgt aggtgatgtt gtcgcgcagg gtgccgtgga cgacatgggt gttctggtcg
     8701 acgatggcga tgcgttcgcg gcactcggca cgggtcagtt cgccggcggg ccgtccgtcg
     8761 aagaggaggg ctccggagtc cggttcgtag aacctggcga ccagggcgaa gatcgtgctc
     8821 ttgccggctc ccgaccggcc caccagggcc gtctggcgcc ggtgcgggac ggtgagggtg
     8881 acgccgcgca ggaccggccg gtccgggtcg tagccgaagg tgaggtcccg cagggcgagg
     8941 gcgggctcct cgtacgcggc ggcctgccga gccggttcac gggtacgcgc ccgtaccgcc
     9001 ggcatctggg cctgcgaggg ctctacgggg agggcgaggg cgtgctcgat gcgctggtat
     9061 gcgcccatgc cgcgctggat caggccgacc gcgcggaaga ccgacgacag gggcagaacg
     9121 aggtaggagg catagaggag gaaggccacg aggtcgccga gggaagtggc gtggccggtg
     9181 acacgcaggc cgccgatgac caggacgagc aggaaggaac cctggacggc gagttcgacc
     9241 gccgggctca tcaccgacgc gagtttcgcg gtccgtacgc cagcatcgtg tgccgactcg
     9301 atgcgctcgc cgatgcgccg cgcctcacgg tcctcggcgc ggtgtactcg caccatcggc
     9361 agtgcgccca gcgcgcgttc gaggtcggcg gcgatcgcgc cgacggagtt ctgcatctgc
     9421 tcggaggcgg cccggatgcc tttcagcagc gacgccacca ccgcggccgc ggccgccacg
     9481 gtcagggcga ccaggagaag cagcagcggg tcgatccaca gcatcagggc gaccgcaccg
     9541 gccgcgacca gcgccccggt caccaggtcg acgagggcct gggacaccac ctccctcagc
     9601 agggtggtgt cggcggtcac gcgggagatc agatcgccgc tgcggtgccg gtcgtactcc
     9661 ctcatctcca gcctgagcag ccgtcccacc agcccgtggc ggagttgccg tacgacccct
     9721 tcacccatgc gttccaggac gaagcggccg acggcccccg tggccgcttc ggtcacgaac
     9781 agaacggcca ggaggagcag caggggccag aacacccgtc cgtcgccgct cacgtccacg
     9841 atctgcttgg cgacgagcgg ctgcgccaac cccagcgcgg agcccacgag ggtgagcacg
     9901 gtcgccacga cgacggaggc ccggtgcccg gtggtcaacc ggtacatggt ggccaccgcg
     9961 gcccgtgtcg agcggtccgg cacctgtgcc ggggcggccg tcatgggcgg ctcggccggt
    10021 tcgcggtcac gggccccacc gcgagcaaac gcctgaagta gtcgtcgggc acgccttcgc
    10081 cgatgggccg gccctccgcc tcgatccagg cgtgcgcgtt gaaggggggc accacgctcg
    10141 cccctgtgca ccacgtgggc cagctgcccg tcagccggca cagcaaggcc gcgcccagcg
    10201 aacggggcag acagcccttc ggcccggcgc agaggagact gaccgcgcac atcgcgtccc
    10261 gggcgctctg cgcctgcgcg gcggtggcgg gcgcggctcc gcggcgtacg gcgccgagga
    10321 cggcgcggat ccggcgcggg ggcaacagcg acaggacgac ggcaggaagc agtacgaggc
    10381 gggcggccag acgccgggtg aggggaacgc cggtgggccg ctccagcgcg ctcggggtcg
    10441 tcatgaggcc agccccgacg tccgcagttc ctgcacgaga gccgtgacgt ccggctccgc
    10501 ccgggcccgg tcgatgtcga actctgtgac gagcgcgtcg acggccgccg cttcgtcgcc
    10561 gccttccagg agggtcttca ccaccagggt gccggtgggg ttgagctccc agtagtttcc
    10621 gctgcgctga tccagcagga cggtgccgta gtcggtctcc gcggcggaga catcggggcc
    10681 gaaccgcaat gccatggtgg gtgactgcct ttctccggtg aagggcctag cgtgtacggg
    10741 cggcagacaa gccgcgcagc cagacttcgg cggcgatggt cgagtagagg atggcgtcgc
    10801 gcagggccgg ggtggagggc cgctgggcga ggcggcgcag cgcgttcccg tcgaccagcc
    10861 cgagctgctc cagccgcgag tcctcccaca gcgtcagcag gtcgccacgg tggcgacgca
    10921 gtccgtcggc ggcgtccatg gaagcggcgg ccttggtggt gcgccgcagg cagccgtcgg
    10981 gcacgatgcc gcgcatggcg gcggtgagaa ggggcttgta ctgccagggc gacacgcgct
    11041 cgctcggccg gacggcgagg gacgcctcga tgacgcggtc gtcgaggaac ggcgaggcca
    11101 tcggtacgcc ggcacgggcc gccatccggt cccactggcg gatgatgcgg gtgcaggagc
    11161 ggatctgctc caggtcggtg tgcaggccac ggtccgggtg cagcggcgtg acggtcgcgg
    11221 ccgcctcccg cagcgcccgc tgtgccagcc gttccgcgtc gggcgtcacc cagtcgaaga
    11281 ggcggggagg catgccccag ccgaggctgg tggtgaccgt ggcggggacg ggatcgcgca
    11341 gccggccgct gcgatcggcg agccacttcc cgtacggccg tgagtcggcc agcgcacgga
    11401 cggtgctgcc cagcggccac tgccacagtg cccggaagcc gcgcaactgc cgcatcgcga
    11461 acagcggacg cgtacgcagc agcctgtggt agtacgcctc ggagcaccac gccacatggt
    11521 cgcccccgat gcccgtcagg tgcagccggc tgccccgctc cgccatgccc ggcaggtggt
    11581 gcagcacccg cgaacggtcc atgacgccga tggtgggttc gtccagcagg tcgtcgatgg
    11641 agagcagatc gtcgtagacc agcggcgagg catcggcgtc ccacaccaca tgctcgacgt
    11701 gcggcaggtg cttcgccgct tgcccggccc agtacagatc ggtgtcggcc ggatcgcgcc
    11761 ccggccaggt actggccacc acccgggcgg gcgagcggtc ggccaggaag cagatggagg
    11821 tggagtccag ccctccggac aggtcacagc tgaccacacc gccctggcgg gtgcgggcgc
    11881 cgacggcctc ggtgagggcc tcacggacca gcggggcgcc gtcggcgagc gtgcggaccg
    11941 gctccggcgg tgtccaccac cgcgagtgac gtgcgctgtg cccgtccgcc ccgatgacca
    12001 gcgcgtcatg cgggggcacg gcggtgacct cgcgccacag cggcgcctcg aacagcggat
    12061 agggcaccgg ccacagcagc cgtaccgcca gctgctgctc gtcgggagcg gtgccgagcg
    12121 cgtcggcgag tacgtcggcg cgggtggcgg ccacctgtac gccgtccacg gcggcgtgga
    12181 agaccagccg cagcccggac gctgtgccct gcaccctgag ccggccgtcg agggtggcga
    12241 cgaggtggaa gctcccgggc agggaccggg ccagcgcgtc cagttccgcc agatcgcgca
    12301 ggcgttctgc gtggcgcttc agtccggcgg catcgatcgg gcagcagccg ataatggcga
    12361 gggccgcgcg accggtgtgc gcggtgacga gctcctggtc gtcccagtgc cccaccagcc
    12421 acggccggcc ggaggcgtgt cgaagggttc gcgttccggg gagggcgaag gagcgggcca
    12481 cggcggccgc gtcctcgcgg tcggtgaaga ccgcgaagtg cgcgtcgccg gggcccgtcc
    12541 ccgcacttgc gtgcagttca gtcatgacgt caggtcagga accgtcggtc gtcagttctt
    12601 gctgaggatg agccggtcgt tgccggagct ctgcaggagc ccggtcttct tgcggaacgt
    12661 ccccagccgg accagcgtcg gcgcctcgta agccttcttc atgacctctc ctcaggtgca
    12721 ggtttcacga ccgctttcct ggccggcggc gcacgggggc tccgatgcac tgccggcctt
    12781 gcccagggct catcgggaac ccggagcgga agcgggcgca gcacatagct atgtgcataa
    12841 ccggatggca tgacaagagc tggagagaaa aataggacaa tatgcaaagt tcaaatatgg
    12901 tcgggtggcg gggtcgctac tttcggattc aaccaggaac tgcgcaacgt gaaacagatg
    12961 tcgcgcaagg acgccgttcc gacctgcgca tcggcggcta cccggtggtt cggtcatgga
    13021 acgggggacg gcggcagctg gacggagccg ccggggcgca ctccgacctt ccgctcacgc
    13081 ttcctctctc tcgctttcct gctgaatggc cgggatgctg cccaccctgg ttcggcagct
    13141 ctcttgcgtc ggtcgagcgg tgatgcagcg accggggcag cgtatgagcc ggcccgtggc
    13201 cactggcgtt gtggaggtgc cctcatgagc gaagtcgtgt ccacagaatg aacgttcacc
    13261 gtatcttcat agtgcctggt agccgtagta tcgccacgct tcgccacccg tccaccttga
    13321 tgatgggtag gcggtcgtcg cgcatgttac ggacccgtcc cgcttcttcg ggcccgtgtg
    13381 aggccgggag gatgaccatg gttcatatcc gcacttctct cactgttcgt cctgcgcctc
    13441 agcgcaggtg acacatgccc catggcttcg tacggtcatt cgatccacga aaaggcgtcg
    13501 gcgtcatcca gcctgatagt ggcggctccc cagtgactgt ggagcgcaat gccgtcgatt
    13561 gcgcatgggg gctgagggag gggcaacggg tcgagttcga tctctgcctg gacgaaaacg
    13621 gcctctgggt cgacaacgtg gatccaatcc ctgacgtcca tggactttga ccagcggtgt
    13681 gctcagccag gtgtatcgag agcgaccaga tgtatcgaga gcgaagagcg caggccccga
    13741 acgggacgtg cgtcgtccgc gtccggggcc gcttctggaa ggctttagac ccggcggagg
    13801 ttcacggcct tgccgtagcg ctggccgagc cagatcttct ggttggcggc gctgccggcc
    13861 aggcgcaggt tgtcgtaccg cgcggtgaac tcgcctcccg ggttgaccgt gacgatgacc
    13921 cgctccaggc accagctctc gttcggctcg ctgccaggcg gctcgtaccg caggtagacg
    13981 gggtagcgat ccagatcgtc ggtgtccagg gctgggaagc gcgggtcgtt gcggtcggcg
    14041 tacaggacgt tggagccctc cccgaacgtg taggtgaagt tgtcaccggg ttcgaagtcg
    14101 ttgtggtccg cgtccaggct gaattcccgg ccggcgatgc tgacgtacac ccatccgccg
    14161 acgttggctt cgctctcggt cgcggtgatc aactggacgt tgactttggt gatctctgcc
    14221 actgcttcat cctctcgttt cgcccggccg ccacgggggt gcgggtgccg ggctgaccac
    14281 ctacttgatt acccagcgca atcactcgaa cgcgtagcgt gtcactcttg cgggtgggcg
    14341 cgtcgcagca ctcatccgct ccgtgagtac gcccggcgcg gggctctcaa cggggtgtcc
    14401 cggcaccccg cccaatgggc cgaattaatg gcatgactgg gggtaggcga cctctcacgt
    14461 tcggtcaggg tgtgcgccag ggcgaactcc ctgaccaggg gaacgatggg agccagtcgt
    14521 ggacagaacc gtcgaagcac tgcttgacca ggtccaggta cgcggcggtt acgccggccg
    14581 gcaagaggcg gtccgcgcgg tgcaaagcgt gctcgatgtc ctgggagcgc accttgtggg
    14641 agatgaccgt acggatctcg cacgtctgct gccgcgtcag tgcgctccgt tgctcaccga
    14701 cggagcgccg gccagcgaac cactgacgcc ttcgggcttc atcgacgctg tggcggcacg
    14761 cgacgagatg gacgcggcgg cggctcgccg cgctgtcacc gcggtgcttg ccaccctcgc
    14821 ggaggtggcg gacgacgtcc tgttgcgccg tattctgacg cagcttccgc cggggcatgc
    14881 cggactgttc ggccgtacgg atccggcgtg aaccgcccga attcatgtgc gtctgtggag
    14941 cggagggcac gaacaggcat cgtggcgcca ggcggcaccg atgaagtcat gcttgcgtca
    15001 ggcgcccgat ctcttgcggg ggcaaaccgg tcagctgggc gatccggggt gccgggatgc
    15061 ctgcggtcag cgcgcggtgg acgagggctt cccagtcctg ggtcgtctcg cggaaatcaa
    15121 ggagctcggc ctccacgtcc gtgacggact ggggtgcgca ctcctgctgg acccgcagtg
    15181 cttcgtcctc gctcagtggc acgggcaggt gctcggcgtc ctcggggatg agtacctccg
    15241 acccggcggg aaggatccgg acctgctcgg aagcggccga gacggcgtgg gcttgcagcc
    15301 acccgcgtac ggctggtgtc tccgcgcact ccagcggacc gacagcggcc aaggcggccc
    15361 ccagcagcgg atgccggtca ggaagcaaga agaggtgagc gtcatcggcc atcgcaggca
    15421 tcgccttctc gatcggacat cagcggcgca ctgatgctag cgcccctcta gggccaaacg
    15481 gactcgaccg ccatcgagaa caccacctcc gcaccggcgc caagtgcacc ctcgtgggcg
    15541 agcctgtcgg ccaggctgtc gggcaggcgc acacgatggg atttctcaga accgccgaac
    15601 acgtggtgga gcgatggaca acagccctgt ggggcttcct gcttcccgcc agacagcagc
    15661 agggcgaggt gctcgccata ctcctgcggc aatgcgacga caacagcctg atccttggcc
    15721 ggcagcgagt cgtggccccg aacaagttcg tcattgaact gcgtccggac atccatcggc
    15781 agctctcgtc ccacgccgtg ccggtggagt cactcctcgc gaaccaggta cgccgtcacg
    15841 ccgccgaaca cggctacacc ttcgtcggcc cggtcgttgt cgaccttcgt tcagccgaag
    15901 gcgctacaaa tgctcggttc cgcatccgga gcgggatcgc tccggcggag aggcggtcgt
    15961 acccaagacg cgctcctgcg acgcgatggt gagcaggcgc ctgacgcgaa gcatggcgcg
    16021 gtcaggcgtg agtgagcatg cccttgcgca gtcgagccag ggtctgggaa agcaggcgtg
    16081 agacatgcat ctgagatgcc caggcgctcg ccgatctgcg actgagtgag ttcctcgacg
    16141 aagcgcaggt gcaggatcct cttgtcgcgg tggccgagtc gggcgacgag cggggcgagg
    16201 ctgtggaaat cttccacgag ctccatggcc gggtcctcgg ctccgatgaa gttggccagc
    16261 gcggcttcac tgtcttcgtg gtcgccgttg ctggcggcgt cgagggaggt ggagttgtat
    16321 ccgttcgcgg ccagacgggc ttcgatgacc tcgtcctcgg tgaggttcat caaggcggcc
    16381 agctcgctgg tcgtgggtgc acggccgagt cgggtgctca gttcgtcggt ggccttggcg
    16441 agttcgaggc gtgcctcctg cagacggcgc ggcacgtgta cggcccacga ggtgtcgcgg
    16501 aagaaccgct tgatctcacc gacgatgtag gggacggcga aggtgacaaa ctgggtttcg
    16561 cgggacagct cgaaccggtc gatggccttg atcagtccga tcatgccgac ctggacgacg
    16621 tcctccatgt cgtcgccgcg atgacggaac cgtctggccg cgtagcggac cagggacatg
    16681 ttcatctcga tcagcgtgtt gcgcgcgtac tgatgctccg gtgtcccctc tccagcgagg
    16741 cgagctgatc gaagaagtgc ttcgacagcg tacgagcgtc ctgcggggcg agccctcctg
    16801 ggtcctccac cagtggcgtg tccacttggc tgcgatccga actcgtcttc gtcgccgtcg
    16861 tcagcactgc caagacccct ccctgattca ccggccctct ccttagacgt cgtgtcattt
    16921 gttgaggcgt ggggcagtct gcgaagtgag tgtcgccagt tggtgtaggc gctcgtagta
    16981 ccggagatct tccgcttcca tgaggtgggg caggatcttg tcgagttcgg aaatgcagtc
    17041 gcgcaggacc tggtagcgcc atgcgtcgag ggagccgccg ttgtcgcgcc aggtcgatac
    17101 gcatccggcg atgtccgcgt caagcatcac catgtcgatg ccctccagtt ccgcgccgcg
    17161 cagcctggcg gggaacggcg cgtccaagtg ttcctgccac agacgggcta cgagggcttc
    17221 gcgctcaatc tctccattca cagggaccat catccttgac gggacctggc tctgacgccg
    17281 tcaggtgggg agtcggcgat agcagatcag agccgcagcg atgccggtga aggcgagaaa
    17341 gtgctcggcc ttgcgctcgt agcggcgatg caggcgccga cagccgccca gccagctcac
    17401 cgtgcgctcg acggtccagc ggtgccgacc gagtcgggcg gaggactcga cgcctctgcg
    17461 ggcgatgcga ggcacgatgt gccgggttcg gagccatttc cgcagatggt cgtagtcgta
    17521 gcccttgtcg ccatggagtt tggcgggccg cctccggcgg ggcccgcgcc gggagcggat
    17581 cggcgggata ccccgcacca gtggctccag accctggctg tcatgggtgt tcgcagcgga
    17641 gatgccgatc gagaggggca gaccagtccg ctcagtgatc aagtggatct ttgatccttt
    17701 cttgccgcga tctacgggat tcggacccgt caggtccccc ctttcatcgc gcgcatgttc
    17761 accgagtcga tggcgcaccg cgaccagtcc agctcgcctc gggcgccgag ctcatccagg
    17821 accaggcggt ggagtttgcc ccatacgcgg gcccgactcc actccgtgaa gcggcggtgc
    17881 gcggtcggcc cggacgggcc gaagcccggc ggcacctgcc gccacgtgca acccgacgtg
    17941 gccacgaaca agatcgccgc cagtacctgc cggtcgccat acctctgccg accaccgccc
    18001 tgcggccgca ccggagcagc cggcaccacc cgctggaaca actcccataa cccgtccggc
    18061 accagacgtt ccaccatcgc catcacggaa cccagcctag tgatcaagcc agttgcgaca
    18121 agccgctacc ccaaaaggcg ctcgccatgc gcctgtcacg aactgggtct ggcaccctcc
    18181 tgcccgggaa ggacttgcgg aaccgaaggc gaagggggtc ttgggccgcg accgaatccc
    18241 ccactggcgg tgttggccca gcggcggcag gggcgtcggc gccgggaggt ctgctcgacg
    18301 tgcagaatgt ggcgcagtgg ttcgacatgg acgacgagct ggccagtctg ctgaagggcg
    18361 agtagaggtg ccccgcgcct cgcggcggcg gatagatgcc gccgggcggt atgcggtcac
    18421 cgtccgctta gtgtcgctcg aggtcagccc cgcctggctt gagttccctc agttggtccg
    18481 cgccagcggc ctgtcgccca gccagaccgg atccggggcc cggccctgaa ggacgaggcg
    18541 gcgttcaagg gctggccgcc gttgatctgg accagtatgg acggctacca ggtcgacgcc
    18601 gatcgggccg cgctggacat acgaatgggc ggtggtcagg agaaggtgac ccagttccgc
    18661 tggttcatca acggcacggt cgccccgcat gccgccgccc actcgagcga taggtcgtct
    18721 gacagcaggg atgacttccc ggtgtcgcgg tcagccggac aatacagcct ccgtacgagc
    18781 ggcttgccgg acatcggact ggggcaatgc cagagcctcc gcgagttcgg ccagttccag
    18841 ttgagtgggc tgtacggggc cactggcgcc atcttcagcg aagacacgga tccgcggggt
    18901 gcgaatccct gtacggtcgg cgagggcctg cgcgttcagg tgcgtgcgtc gcatcgcact
    18961 ttgcagcagc tgggcaaggt cagtcatgat ctttacctgc ccggtgtcgg tcgtcgcagc
    19021 ctgccccatt caggtgattc tgcttcttta cggaagaaac tgtgataggt gcggttcttg
    19081 cttgcgctgc acaacgaaag aaatggcagg cagataggcg tccgaccgat gaactcggac
    19141 agcaacccgc tgcctctctg gattgtgcga gtagttggcc ggagaacggg aagacgcaat
    19201 ccatcatgaa acggacactt tacgacggaa ggtaggaggg cgcgatggtt gccgggcccc
    19261 tcagcgacga cgcaagcagc gtgcgacccg aggccgtcga tgctttcgcg gtccgcttct
    19321 aaggcgagat cggcgacctt accgacatgc gtcgggcggc agggctattt ctcggcagcc
    19381 tggcgcacca ggacccgccg accgactcgg agagctgggg cgacatcctg ctcgtggtga
    19441 ccgaactggc ggccaacgcc atccagtacg cccccggccc cttcactctg cggatacgac
    19501 gcgccttcga cggggtgcat gtggcagtgg gggaccacaa ccccagccca cccgcacccc
    19561 ggccctgtga cccggcgcgc ggtgccggcg gcctcggttg gcatctcatc caggcgctct
    19621 ctcgccaggt cagcatcgtg cctcacgagg gagggaagga ggttcacgcg ttcctgccct
    19681 ggtgagcctt caagatggcg ggaacttgac gatccggtcc gggctgtcct tgcgccactg
    19741 ccgaggccgg ccgcagtgct gccgggactc ggcagcagag gcagtggagg acggactcag
    19801 ccccggctga cgaagggaag gtgaccaacg tggccgcgaa catgcattcg gatgagcggc
    19861 gtgtcggtgt tcgcagctac gcggaggttg acgtcgcgct caacggtctg gtagttcgcc
    19921 ggaaatcagc accccggttc tccgcaggcg cggctgccgc gtatgagtgg gccatgggcc
    19981 agactgtccg ctcaccagtc accggcgcag aggtgcacgg catccccgac ctagggctcc
    20041 tgaccgccga agtggacgcg gcggtcatcc aacttgagga tcccaccacc ccagtcggca
    20101 accgtgacta cacccgcgga gcacatgacg ccctcgcttg ggtctgtgga tacagcgacc
    20161 aattgccctg atcgcatagg agtgaagcag gccgaggcga gcctccggag gaggccgtgg
    20221 aatgtccgtc ccgtcccccg aggactctgc gggatcgagg acgggtaccg cttccccaaa
    20281 acggaaccta gtgcacttgg gagtgatgac atcagtgcct accgtgatga acggtggtgc
    20341 gcagcgacgg ggccggccga ccaacagcgg tacgccccac ggttaccgga gaaaccggtg
    20401 agcggaccgc tggaggcagg tgttgacgct ctcggtgcct tgaacgtaag ccgacagggc
    20461 tgtccttggc tggacagccc gcggcttcat acgtctgggt acccaacgtg atagccgggc
    20521 tcgaaacacc ttctatcgag tgatgccgcc gacggaaccg caggtctacg gtggtcgacg
    20581 ggtctcgcga aagggcgggg cctcctctcg atgcgggctc tgacctctcc taccggaggt
    20641 cagagcccgc cgcgtatgtc gtgatggctc gtcggacctg cttggctgct gttgcctgat
    20701 cttcagccgt cagcgacctc gtccctgcat ccctggcgcg ctcggctggt gcgggggcag
    20761 cgactccgtc tggattgggc ggacggttcg cgtatccgtg accgtgcggg cctgggcggc
    20821 tcgggagctg gaggtaggca gctggacgag gcggctgacg cgccagatga gtgcgcgtgc
    20881 cggtgatcgg gtgtcgtcca gtggccgctg gtcgactgcc tgcttcaaca gcgtggtggg
    20941 ttcgtgcccg gctgcttcgg cgtcggagag ggcggtggcg agtgctgccc aggcgtggtc
    21001 gtcgaggact cgctgggcgt gtgtgggtac ggcttcgtag accagggcgg cgagccgctc
    21061 gaccgtgggc gctgacggtt tgcggtggtc gagggtggcc agcgggactg cggcggcttg
    21121 gtcgtaagca gcctgcaggt ggacgagcgc ttggcgggcg gcgatgactt gctggtcgtg
    21181 ttggcggagc tggtgccagc gtccggcagc gatgaccgcg aggatggcca cgtcgaggaa
    21241 catcgccagc atggctccgt cgcgcggtgc cggctgcgta cgcagggctc gtatggcgcc
    21301 gcgcagtgcg cgggcgtgtt catgttcggc gcggatgcgg gagcgggtgg cgcgttcgaa
    21361 ggcggcagcg gcctggcgaa gttgggggcg gatttccttg agggtgagga ggggcagggc
    21421 gtcgagggct tggccgaagg cggcgatgtg ggcctgggcg gctgcatcgt cgctttggtc
    21481 gaggtggtgg gggatgtgct cggcggcagc ggtcgcctgg tgccacgggt cgggccggtg
    21541 ctgctgcgtc tgggtgagct ggtcggcggc ggtgaggcgg tcgcggatct gggggaagga
    21601 caggtcgggg gcgagtctgg agccggagta ccagacgggt tcgccgacgg cgttggtgtc
    21661 gccttcgatg gcgatcttgt atccacggat gtcgccggag gggaagcgct ggatctcgac
    21721 gagcacgctg tcggtggcgg cgaggatgcc gaggaactcc tcggggctgg tggccaccga
    21781 gaccgcggtg cggacggtga agcgcaggcg ctcgcgggcg gtcatcgcgt ggccggcccg
    21841 ctgggctttc tccttctcgg cgcgggttgg ccgtttggcg gcggtccggt cgccgcgtac
    21901 gacctgctgg aggccgtact ccttctcgat ggcgaccagt tccttgtcag cagtgaggta
    21961 gtcgttccag tggcgcgctg gccggagatc gcctcggacc ttggtggcgg cgatgtggat
    22021 gtggtcgtcg gcgtgccgca ccgcgaccca gcggcacgcg tccgggtccc cgtcgggggc
    22081 gatgcctgtg gccgccacaa cgcggcgggc gatgtcggcc cactcggagt cgctgaggtg
    22141 gcggtcggtc tcggcggcgc ggatggagca gtgccacacg tgccgctcgg gcgcacggcc
    22201 gtggcgccgg gcctgcttca cgtgcaggtc gaggtccgcc acgaggagct tctttgtggc
    22261 ggcggggtcg tcggcgcggc cggggtcggg ggcgtagccg tcgaaggagg cgaccaggtg
    22321 ggggtcggtg tgctcgttgg cccggccggg gccgtagagg tagcggatga ggccggcggt
    22381 gtccttgccg ctgctgattt tggcgatcac ccggctgcct tggtggagac ggcctggttg
    22441 gcggcttccc tgatgtggtt gacggccgtg ccgaccgcgc ccagggtgcg ttcggcctgg
    22501 gccaggacgg cggtgtcccc agggtgtgga tggccgccgg agttcagctt cttggtgacc
    22561 tggtt
//
