LOCUS       NZ_LIYH01000005        25278 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold5, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000005
VERSION     NZ_LIYH01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 912609)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912609)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 250064
            Orig. end                         :: 275342
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25278
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25278
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25278
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15278](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15278)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            602..1252
                     /locus_tag="AMK26_RS22450"
                     /old_locus_tag="AMK26_22105"
     CDS             602..1252
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644433.1"
                     /locus_tag="AMK26_RS22450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22105"
                     /product="hypothetical protein"
                     /protein_id="WP_073756521.1"
                     /transl_table=11
                     /translation="MTAELLERPATVTVPDTGAGRLIVPATEGTTTVPTYRVGAPDIQC
                     RYPVIVGEDQVIGRAYRWHRDWLVLTTEGEHNLRRPPKGVPGTDMAAAHLVQQYAAGRI
                     GTVPLDQVLAEAPTPLCGPVPLLHPRMPVTDRNIESALTAFAGLAAHHWRAVLTGFPGS
                     DNHWYLSCELCDWEGPKFWSHLRGRNGEPPSPRRHKGGCIGEDKVRRLIPAYQ"
     gene            1313..1741
                     /locus_tag="AMK26_RS22455"
                     /old_locus_tag="AMK26_22110"
     CDS             1313..1741
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644434.1"
                     /locus_tag="AMK26_RS22455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22110"
                     /product="DUF6197 family protein"
                     /protein_id="WP_073756522.1"
                     /transl_table=11
                     /translation="MPTRHTPESLLIADTPAAILEWAARHIEHVGIHQGRRLFAGPGRT
                     ATLPCWPRGALEVAAGHGRGAAGRTYDWDRINHARDQAFGLLAETLTGHPIEADEPASA
                     KALHREVIDRWSAEPGRTAADAAHAFRTAAARAAHALF"
     gene            1783..2181
                     /locus_tag="AMK26_RS36725"
     CDS             1783..2181
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040345.3"
                     /locus_tag="AMK26_RS36725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6181 family protein"
                     /protein_id="WP_143608593.1"
                     /transl_table=11
                     /translation="MNETTASRSTTRTPSRRGAATPSRDGVHRLSVPLAPRLSATELIR
                     ALLAAPVETDLSTLDPVQTRSLIADVLTQHGYDVLDRSPYYPELDRHQEALRAVRRAYG
                     PRFLDAPDEQAVLADPLREVLAAGSGKS"
     gene            2178..2786
                     /locus_tag="AMK26_RS22465"
                     /old_locus_tag="AMK26_22120"
     CDS             2178..2786
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040384.3"
                     /locus_tag="AMK26_RS22465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22120"
                     /product="DUF6349 family protein"
                     /protein_id="WP_073756524.1"
                     /transl_table=11
                     /translation="MTASTTEPTGARARQTYYWRVRNARTPQPPMSAGHVWHIQPGHPG
                     GAYCDLGHELEPPSHHTPTLLSRSRPTGRRGYEQEFRGGCLACDWEGPVYSGDGFGDGD
                     NEAVEDAHDHCFPGWRTLPPITTVEDRWAVPRSRSRWAQLIAQYPAGWVDQGAPVVAWR
                     RYRREAHAPPHAGRPRYELRITRPPRDRVHSPADQGALF"
     gene            2984..3262
                     /locus_tag="AMK26_RS22470"
                     /old_locus_tag="AMK26_22125"
     CDS             2984..3262
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040353.3"
                     /locus_tag="AMK26_RS22470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22125"
                     /product="DUF6211 family protein"
                     /protein_id="WP_073756525.1"
                     /transl_table=11
                     /translation="MLCDRHPDCPQPGDIAQLTRGNSIGADPTDTFVIVEDFPPTGRHL
                     VLNLPVDHPDRADWAAAVPLADIATLTRLEPAGSRTWTPAPDPDDIQ"
     misc_feature    2985..2995
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            3307..3960
                     /locus_tag="AMK26_RS22475"
                     /old_locus_tag="AMK26_22130"
     CDS             3307..3960
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447328.1"
                     /locus_tag="AMK26_RS22475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22130"
                     /product="hypothetical protein"
                     /protein_id="WP_241838017.1"
                     /transl_table=11
                     /translation="MSRKTGRTLYSRADLRRVHGISESTLQNLWTDRENNGHPPVADTI
                     DGVMHWDGDAWATWHHELQRQRAAASTTNPPKLDGDPEEMVGPAEAAKVCGFADSTTVS
                     HYVKNPPEGWPEPDGWDELPTRRRPKWKRWRLWQYLADRKGRGHAGGRPAGRRGLAYPY
                     QGDERLTLARQAIKANPGAKNAELIPQLQEQTEKTYSRTVWNLILKSAREHPEE"
     gene            complement(4210..4488)
                     /locus_tag="AMK26_RS22480"
                     /old_locus_tag="AMK26_22135"
     CDS             complement(4210..4488)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS22480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_22135"
                     /product="hypothetical protein"
                     /protein_id="WP_073756527.1"
                     /transl_table=11
                     /translation="MANRNDDLADLTRQAVDTAGALRMLVERMNDLGLRMSDHSDADLL
                     AVASDYSDEDLRTVASALRGTAMIMLMDRANAELLSEWLRKLRSEAT"
     misc_feature    complement(4620..4635)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.71"
                     /tool="antismash"
     misc_feature    4666..4680
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     gene            4741..9174
                     /gene="mobF"
                     /locus_tag="AMK26_RS22485"
                     /old_locus_tag="AMK26_22140"
     CDS             4741..9174
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="mobF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447327.1"
                     /locus_tag="AMK26_RS22485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22140"
                     /product="MobF family relaxase"
                     /protein_id="WP_241838018.1"
                     /transl_table=11
                     /translation="MIGPSDEQVEYRLTGGHGCGKSTTVDAALLVAAIEAKAEAAGAPV
                     ASLLGSREAKRAFFRARGLIRSKGAARFTGFDAVEVASAAGLDARDLYGEQVLPRPAAD
                     GQVDYHLDASERPLVWIGNGLNEFDITPGSVLAPEHFQAARRLMHGEDPRTGQTLVEPK
                     LAIAPAAKLPAAPLARAIRRAAAERSVNPVTLLDSKRKQDAFRRMESQLKRFGESHRVP
                     ASTVLKLADAVGIDAVALYGEDVLGKAVAAEAGGHLDARALLRSVEARATETGQQPADL
                     FTAASMKRRYVQTAGEGERRLRDLPMAVREAVAMAKAAGLAPEDVWDAEEIKAALLEGR
                     VQVGNFGADVTLDLAKSKSAFLAYAPEEIAAQVEGIYTSAGRESISALERWTAYGMRGR
                     HGDGDEAETVGTSGFSGWMMVHRAARPVDGAPYGDPHFHLHFTLANMVKGIDGKWSTMA
                     SGGRDLHRHARATQSLMNARIRRELTDKFGISFRREERTGAWEIAAIPEATIRLFSKRD
                     NQVRDLLTKLGIDYDSATTRERTAASTASKAAKNGEAAGVADDVLREYWQAEGRAAGDE
                     PEAIAASAMQQDSPKQNPGLDELCATIFDPKTGLTSHSKDFTHAAAIAAVLDALPYGVA
                     DAEEAERLTDSVLRHAGYAVKLNPKGAQHFAHADRYTTADVVAAETLIVSEATSRLGAQ
                     AAVVSRDTVEMTLSTVEAQHGGTFKFSDEQRAVLDRLLTAGHGIDAVVGIAGAGKTTIM
                     DTARQAWEAHGLVVAGASTAAVAAANLKAEAGITSRTLASWLTGIRTGGAGLNGVDVLV
                     VDEAAMCDDRDIAELLTHAAKTGTKVVGIGDPKQLHSPGIGGSFAAVHHLVGGLTLSQN
                     FRQKDMVERRALELWRDDNRVEALRTFAGTGRVHALADKDATLAAMLTVWADKRAAHTD
                     DHTAVQQLLMLAATNEIVEELNLGARALRKASGNLTGPEHTYALPGGGELTLSIGDQVL
                     LRINDYRGKRSRGENEDVLNGYRGIVRAVDEGRRVLVEWREKTADGHHDVAEWVDADYI
                     AQGGLSLGYAITGHKSQGLSVHEALVYGPGAQANALYTMMSRDKKESHLFLPLSVYESD
                     ADRARGGTALTEQEQLDRAVAGLIREIESGTEERMILTELPKDMVPAHVRQAVADLPTP
                     YASGTGTPHEADAAHDAPESDDRRTADTTERPATPTTLPGPAPRADRSYAHLSSAALRD
                     AARKAVTAARATRTAAEKAEATADRAAQQAAAGTGPNALAFNRRHQAIADRAVAIHELR
                     ALGGTIGEHTARLRDTQERIDGLDQQLAATGRFGRPVLRRDARAAVEADRMELLRSYEE
                     TGRELEQMNKRLDEVAEQAGPVSEHEAVLTEADMPQQDKAALLRRAKEKDNQAAKRLQA
                     EAAKARSTARGADQRAAGLQEEMARRTQRGLQHADAEESASPSAPKPESSYADRTTADF
                     PQQYPPSEAVQDAPSV"
     gene            complement(9191..9568)
                     /locus_tag="AMK26_RS22490"
                     /old_locus_tag="AMK26_22145"
     CDS             complement(9191..9568)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS22490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_22145"
                     /product="hypothetical protein"
                     /protein_id="WP_158071140.1"
                     /transl_table=11
                     /translation="MFQCKLCPSKGNNQEIRGVGTRMAAYRVCSSCDFWLTCWGYAMLG
                     DRDPDGRRVLRIGGRHYLTWTEEQGFPPEIGYAGVEVRHYVLLNDPTGAVHATHRLWLM
                     GTIPESFRDRMPDNAVFVTEA"
     misc_feature    complement(9540..9553)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    9626..9639
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.33"
                     /tool="antismash"
     misc_feature    complement(9863..9878)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.48"
                     /tool="antismash"
     gene            complement(10001..10984)
                     /locus_tag="AMK26_RS22500"
                     /old_locus_tag="AMK26_22155"
     CDS             complement(10001..10984)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662445.1"
                     /locus_tag="AMK26_RS22500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22155"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_338015592.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.2e-32, bitscore:
                     108.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPSPIERAVAAALTGLPIPEVAAQYGMEPTILSDAVAVYDQAG
                     REALARHTSTVDWWQVYLHFTDWAKADETFTAHVLPLLQEAETAGVIGGWWYTRKHPCW
                     RLRLRVRPGIGAQLGAAEGLDRLGLHRLVADGHLVRWWPGIYEPETAAFGGEASMTAAH
                     ALFIADSREAQRLRQHDSPTVGLRELSVLLCTHMMRAAKLEWYEQGDVWDRVITIEHRS
                     ALGDVPAARLNALAQGIRPLLLANSDTMVRPGGPLEPVAECAAAFRSAGQALGHAVQEG
                     TLDRGLRQVLSYHVIFHWNRLGLSMRAQSVLAWAARAAILHGESGT"
     gene            complement(10987..12216)
                     /locus_tag="AMK26_RS22505"
                     /old_locus_tag="AMK26_22160"
     CDS             complement(10987..12216)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490581.1"
                     /locus_tag="AMK26_RS22505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22160"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_073756531.1"
                     /sec_met_domain="LANC_like (E-value: 6.6e-36, bitscore:
                     119.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPAATTAAILEQYTAHLAQPAPPPPDEPWAVQSLADGAAGISL
                     LHIEMASRHGGSWRPAHRWITAAAAGHISAADTAGLFLGAPALGFVLTTVPPSFQHLYE
                     PAWRTLHQHIIDLTHRRVDAALTRIRKGYLPTFSEYDLFYGLTGIGAYLLRTDPEGLPL
                     ERVLKYLVALTRPLAPDGRGLPGWWVPYDPARGDSPHFPGGHGNFGVAHGITGPLLLLA
                     QALRRGITVSGHQDAMWTICAHLDMWCQTGPAGPWWPEHISRRDLDRGRPHHDAPARPS
                     WCYGTTGIARAGQLAGLALRSPTLQKFYEDALYRALTDPEQLAHVTDSGLCHGWAGIYQ
                     TAARAAADALDPRLQTLPKGLGDTLAANAQPGLSGPGLINGDAGTALALTTHASQQAPI
                     TGWDACLLIN"
     gene            complement(12213..15278)
                     /locus_tag="AMK26_RS22510"
                     /old_locus_tag="AMK26_22165"
     CDS             complement(12213..15278)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746441.1"
                     /locus_tag="AMK26_RS22510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22165"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_073756532.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-201,
                     bitscore: 666.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.6e-17,
                     bitscore: 59.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.8e-14, bitscore:
                     48.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASRAAAGYLWQGVAMLRATTSPGPADIPRTLNLDNVAVTRGWLN
                     RIWQREDFRSALELATPVLSDAIEAVVQGRRTEPRHVRRTALSAVSYLLRWQHRPTPLG
                     LFAGTAPVSVGPRASARWRDKHRAMIRPDAEWVTDLVLRLQGTPALLKRLPLVANNAAR
                     VRGDRLVAPGPPSDGHAVLLAPVEISVRNARPVAAAMDAARTPIPYGNLHGHLRDRFPQ
                     ATPEKIDALLTSLVEQQFLIASLWAPMTTVDAFQHLCRELDRLQADSIPEVRDLVHELY
                     ALRDELSAHQPTLSDTSVSAVAARMRALTPVTPTPLLIDTALDCETQLPQAVIAEVQAA
                     VSALYRTTPQPYGYQHWRDYHRRFRARYGVGALVPVMDLVADSGLGLPAGYVGSERGAA
                     LKVRTDRDELLLALMQQVLLDGGSELRLTDDMVDALEKAAGKDERLFVPRVEVAFEVHS
                     PSTRALSSGTFDVLLTAVPRPGSSMAGRFAHVLPPQHQDALAATYRGAPDGLTAQLVFP
                     PRRHRNENVTRTPRLLPHVIELSGHQETDEATIPLADIAVTADPRSFHLVQLSTGQRID
                     VRVLHALEGGTQTPPLARFLAEVAHGRFAAYKPFDFGAGSRLPFLPRVRYRRTILTQAR
                     WLLMADDLPGRKASTEEWENAFAVWRGRLRVPMQVAIIEYDQRLPLDLSHPVHRRALRA
                     HLDNARRLELREVPDADAHGWIGRAHEIWLSLGRSEPDTADVPRARPATALAAGRHLPG
                     DGDVLLAQLHAHPRRYDEILSRHLPSLLAAFGDTPPLWWFTRHREMARPDADQHLNFTL
                     HLPPDAYGAAAQHVRRWADSLHGTGLAAGLVLAPYQPQTGRFGGEAAMDTAHQVFAADS
                     AAALAQIQLTERTDALAPQALAAASALHLVTPLAPDTAAAEEWLVRNLPQGTGRLSRAL
                     RTQVLELAAPNGASVLAALPGGPAVAEAWRARAAAVDAYRKTLTGQRDPLDVARSLLHQ
                     HHVRALGVDPRAEETTIRLVRTAALQHRMAAR"
     aSDomain        complement(14535..14810)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AMK26_RS22510_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="5.40E-19"
                     /identifier="RREFam001.1"
                     /label="AMK26_RS22510"
                     /locus_tag="AMK26_RS22510"
                     /protein_end="248"
                     /protein_start="156"
                     /score="59.7"
                     /tool="antismash"
                     /translation="VANNAARVRGDRLVAPGPPSDGHAVLLAPVEISVRNARPVAAAMD
                     AARTPIPYGNLHGHLRDRFPQATPEKIDALLTSLVEQQFLIASLWAP"
     misc_feature    complement(14817..14819)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15372..15575)
                     /gene="fxlA"
                     /locus_tag="AMK26_RS22515"
                     /old_locus_tag="AMK26_22170"
     CDS             complement(15372..15575)
                     /codon_start=1
                     /gene="fxlA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380187.1"
                     /locus_tag="AMK26_RS22515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22170"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_030881377.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 2.7e-15, bitscore:
                     51.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSATLAPPPVAPAPSADLDDDFAPLDVKVVIAEHSYGHLMCSTG
                     DGCGTTCATGASACGSFTEDPA"
     gene            complement(15627..16862)
                     /gene="fxlM"
                     /locus_tag="AMK26_RS22520"
                     /old_locus_tag="AMK26_22175"
     CDS             complement(15627..16862)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490583.1"
                     /locus_tag="AMK26_RS22520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22175"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_073756533.1"
                     /sec_met_domain="PCMT (E-value: 4e-37, bitscore: 123.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNTTVDPDEATRLRNKVVDELCADGNISSPEVEAVMRKVPRHEF
                     TPDTPLDKAYDTYAAVITKTDEHGVQLSSVSAPQIQAMMLEQAQVKPGMRVLEIGSGGL
                     NAAYLAELVGEGGEVVTVDIDPVVTDRARRLLDEHGYDRVRVVTADAAEPIPDLGEVDV
                     VMVTAGAWDISPAWTAQLKQGGRLVVPLRMRGLTRSVAFTQVTGEHGTYLESESARICG
                     FVPMQGSTAHREELLLVNGTPEIGLKFDDGLPADPHRLDNAVTFPRHELWTGVTVRVQE
                     LIDTLQMAMAISLPGFCTMAVDENSDTGLVAPVNKRFALAAVEDDTFAYLVTRRTEDNK
                     HLEYGVHALGPHAEQFADKIADVLRDWEANRRGGPSPVIRVYPASTPDEQIPADRVIDK
                     VHTRISLSWPSA"
     misc_feature    complement(16842..16856)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(17067..17714)
                     /locus_tag="AMK26_RS22525"
                     /old_locus_tag="AMK26_22180"
     CDS             complement(17067..17714)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143560.1"
                     /locus_tag="AMK26_RS22525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22180"
                     /product="hypothetical protein"
                     /protein_id="WP_073756534.1"
                     /transl_table=11
                     /translation="MTTAADLIVPYITAREGEEAESLLNLRVRLGPDRRPRLAYVDEEP
                     PDRDLRGVLWARYSMSLGNDGMPTGTPRWRLVHPLRQRSTMALLRCQVCTVQLKRSDGI
                     LFLETADDLDYTGPVKTAQPPVCLAHARMAASRCPRLRRKGHVALLARRFPLYGVIGTA
                     YQYGPNGIQALSGTDRPLPYSHPQIGWFLASQLVRELRDYEVVKLDDLVPAA"
     misc_feature    complement(17908..17924)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            17912..19030
                     /locus_tag="AMK26_RS22530"
                     /old_locus_tag="AMK26_22185"
     CDS             17912..19030
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963936.1"
                     /locus_tag="AMK26_RS22530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22185"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_241838019.1"
                     /transl_table=11
                     /translation="MSFAVQRLRLSEDGPVSYTVVGDDGLPVDDVEDFLAYLTARGASP
                     NTVQGYAYDLRDFFVWLGQVGLDFRRVRLEVVAQFFDWLRRPKPARAPEVFVLPGVGQA
                     LENTTLQRKRAALASFYRFHARRDESVPALLGNLLARQPTGSYTPMLAHTQRGGEVEYS
                     PIRIHAHRKPPRTLTDDEVRRLMGACNRRRDRFLIALLDEAGLRISEALGLRHADLNLR
                     KGEVHVVPRENNANHARVKGMKGRIIPVRPELFDRYAVYMESEYGTLDCDFVFANLFRA
                     PIGSPMTRANVNELVERLQKRTGIAHFSPHVCRHTYATRLLRAEVPIEVVAELLGHASP
                     QTTAEIYSHLDVEDHRRVLLSAGIIKDRAPTR"
     gene            19027..21315
                     /locus_tag="AMK26_RS22535"
                     /old_locus_tag="AMK26_22190"
     CDS             19027..21315
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963935.1"
                     /locus_tag="AMK26_RS22535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22190"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_073756536.1"
                     /transl_table=11
                     /translation="MNTPRARAGSDGLLARLMETVRPEFRAEVFCPPRDSPVFFPGECR
                     IPACPTTLTMGRLKLCRTHHHRWAAAGRPADLDGWFAQEDARLRERRQVSACRVSGCNR
                     ARAAHGLCHRHASRWNHAGRPPLESWLGRTLYQPPRKPWSAERTCDFPDCPRWTDSTDA
                     PLCHTHHNRWRKHGRPTLDTWYDDLAHRGDPKIRLDQLTPALRLEFQFGLQHRLDEGLR
                     FTPARDVRRAVTWACEAPITSLLDWDESTWRDHVAPLGPGGKRHGHNVVAFRFIADTRF
                     ALKHLLIADDPWADQYPRDVWDLRHFALAEGETRYLRFGPIPQPWLRELVKRWCRWRIS
                     TNISVNTVAQNLRSLTHLSGHLPPHAAPADLTRARIETWLAALAVDYPDVFTRRATVNS
                     LGRFVADARAHDWQPVLPRDAIIYNDAPPPPPAKPRWISEHLMRQMENPENLALISTDD
                     LRLMVPLLISCGLRMKDARRLRFDCVTHDDTGAPYLTWVNHKIHGRIAFFPISQALADE
                     IAAQQKRVQARFPAGSRFLFPGWMANLNGSKAVSDTWCREQMETWLERIRLIDEHGRPA
                     RVTFHQFRHTLGTRLINANVPQHIVQQLLDHMSPQMTAIYARLHQKTLREHWEKSLKIN
                     AEGEAVALPADHPLADATWMRLSLVRAKVSLPNGYCGAPIQTDCEYANPCLDCRFFITT
                     GDFLDQHRRQREETRKLIGDAEKAGLSRIVEKNTRTLGKLDTIIDALEQAGPQQIVAGG
                     KVTDLDATG"
     gene            21302..21718
                     /locus_tag="AMK26_RS22540"
                     /old_locus_tag="AMK26_22195"
     CDS             21302..21718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963934.1"
                     /locus_tag="AMK26_RS22540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22195"
                     /product="DUF6262 family protein"
                     /protein_id="WP_073756537.1"
                     /transl_table=11
                     /translation="MPPADNARFLVEASKTRSRQARERAEEAIKTAARRSERPTVVGIA
                     NAAGVSRSWLYTQTDLITAINQLQQRAPAPHRNTRHAASDASLQRRLETALERNRQLRD
                     QVADLTRKLENAHGEIRRLRTLAQPPAATVLGPR"
     gene            complement(<21815..21937)
                     /locus_tag="AMK26_RS37965"
                     /pseudo=""
     CDS             complement(<21815..21937)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957768.1"
                     /locus_tag="AMK26_RS37965"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF5999 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCAHTPPCPTAEAPDRDAARPIAYHPEQGWSLLCNQVLLFE"
     gene            complement(21988..22446)
                     /locus_tag="AMK26_RS22545"
                     /old_locus_tag="AMK26_22200"
     CDS             complement(21988..22446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746446.1"
                     /locus_tag="AMK26_RS22545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22200"
                     /product="DUF6302 family protein"
                     /protein_id="WP_073756538.1"
                     /transl_table=11
                     /translation="MSTAMRPARAITVSLRPAEEAYDFEYFRDRLAEPAVLDCAVAVRV
                     FRAPLLAVPVGGPRRGGYMSFELLSLAIATRGLLADRPGFPDLRVRWSPYRDTCHTVEW
                     GEPAPEWWEDDAVFGRFYGYSEAAIAEFVRQHLPTPSSAISEPSPTAP"
     gene            complement(22446..22964)
                     /locus_tag="AMK26_RS22550"
                     /old_locus_tag="AMK26_22205"
     CDS             complement(22446..22964)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039764.3"
                     /locus_tag="AMK26_RS22550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22205"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_073756539.1"
                     /transl_table=11
                     /translation="MTSTAVQHQSERAERIPIRVKDPSVPTHPWTAPLDRAAIERYLSA
                     VREWEPVDWSAVFEDVDALLNGEVSHHAAGSTGRKRAVAPPEYDDADELAQRFRGALMQ
                     LVHRGLRDEADKKHPDIAALIEQARVLRSEELPGDPWQALGHLRRLGRVTLQLAQRLDE
                     VGIVKGLIE"
     gene            complement(22961..23302)
                     /locus_tag="AMK26_RS22555"
                     /old_locus_tag="AMK26_22210"
     CDS             complement(22961..23302)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447317.1"
                     /locus_tag="AMK26_RS22555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22210"
                     /product="ATP-binding protein"
                     /protein_id="WP_079277803.1"
                     /transl_table=11
                     /translation="MRRVTRERLRSYGLDCVAEEATLVVSELVTNAILHSGGRRVRLTL
                     DLEDDLLRIRVHDGVSGRRPTVQHPGDQDEHGRGLALVTAIAHSKRGAWGVDDDGATTW
                     CDLSLAASR"
     gene            complement(23428..23619)
                     /locus_tag="AMK26_RS35785"
                     /old_locus_tag="AMK26_22215"
     CDS             complement(23428..23619)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS35785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_22215"
                     /product="hypothetical protein"
                     /protein_id="WP_079277752.1"
                     /transl_table=11
                     /translation="MTTRTPGDRHRRRNLADASVTPLPALAGLLRRVPGQRRRTGAFSS
                     IDDPDARHDRTSQIGTER"
     misc_feature    23649..23662
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     misc_feature    complement(23905..23914)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            complement(23946..25166)
                     /locus_tag="AMK26_RS22560"
                     /old_locus_tag="AMK26_22225"
     CDS             complement(23946..25166)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571579.1"
                     /locus_tag="AMK26_RS22560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_22225"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_073756540.1"
                     /transl_table=11
                     /translation="MAYDGELFSIGQRIKWWRERRGLSQKMLGDLIGRSENWVYKIEND
                     RMPLDRLPILIALSKALRCSLEDLTGGYVSGIATGGTEHENVPLIRQALSLPASLLPLR
                     IGSISADDFESSVTDAWKVYETQADDRYRDVGARLPILLRQGHAALRDAPAEQESTVLR
                     QLISLYGLHQIWLRRVGEPTLARVAADRGLALADNAGDPALLAAAAWNLACVLTSAGDV
                     DDSYELAQQTIAQCRPNEDSSPEHWSAYGALHLQGAVAAVRATKGPRAWDLYHGAEQAV
                     QRVGSDLNHWHTCFGPTNFAMHEVHLKAEEGDTSEALRAADHVQVNPEVPLERRTRYLI
                     EVMNLNRIQRDDYATVHILGKLLKQSPEEIVFSPLVREAVADLLKREKPMWRDDLRAVA
                     VHIGLAA"
ORIGIN
        1 cccgcacatc cacaacggca ccggcaagcg catcgtccgc gccacaggca accggcacga
       61 cgattggacc tggaccgccc cctacgacga cgtatccgga cgcaagagcg ccgacgagat
      121 gcagcagccg ccccaggccg aggccgccga acaccaggag caggccgagc agtccccgcc
      181 gatcgaggag ccggtaccgg cgtctgagac gtgcgcgtca gcccccgccg caggggcgaa
      241 ctggcaggag ggcatggcgc tggtgctcat cgcctcgaaa aactcccgcc gcacccgcaa
      301 gcgcgccctg tgggcgatga cccgccgcga ggcacaggcc gtgtgcggcg acccccgcac
      361 ctccggccgc tcgtacatgc tcacctggac cgagcggccc ggcactgaag gcaccgactg
      421 ggaatgggtt ccggataacg ggagcctcga cccggtcctt gaagacctgg gcatcacccc
      481 gcgccgcgag tggaccaccg ccccgaagac cgcggccgag gccgcgtaac caggcccccg
      541 cccgcccccg cggccgagcg cgccggggcg ggcccctctc tcaccagaac agggcaccac
      601 catgaccgct gaactcctcg aacgacccgc gaccgtcacc gtcccggaca ccggagcggg
      661 caggctcatc gtccccgcga ccgagggcac caccactgtc ccgacgtacc gcgtcggcgc
      721 ccctgacatc cagtgccggt accccgtgat cgttggcgaa gaccaggtca tcggccgcgc
      781 ctacaggtgg caccgagact ggctcgtcct caccaccgaa ggcgaacaca acctccgccg
      841 accgcccaag ggcgtccccg gcaccgacat ggccgccgcc catctcgtgc agcagtacgc
      901 cgccggtcgg atcggcaccg tccccctgga ccaggtgctt gccgaggccc ccactccact
      961 ctgcgggccg gtacctcttc tgcacccccg gatgccggtc accgatcgca acatcgagag
     1021 cgcgctgacc gcgttcgcgg ggctcgcggc ccaccactgg cgggcagtcc tgaccgggtt
     1081 cccgggcagc gacaaccact ggtacctcag ctgcgaattg tgtgactggg aaggtccgaa
     1141 gttctggtcg cacttgcgcg gacgcaacgg agagccgccg agcccgcgcc gccacaaggg
     1201 cgggtgcatc ggagaggaca aggtccgccg actgatcccc gcctaccagt agcagcccca
     1261 ccgggggcgg cggcagtgcg ccgccgcccc cgcccttccg aaggacagca ccgtgccgac
     1321 ccgccacacc cccgaaagcc tcctcatcgc agacaccccg gccgcgatcc tggaatgggc
     1381 cgcccgccac atcgaacacg tcggcatcca ccagggccgc cgtctgttcg ccggtccggg
     1441 ccgtacggcc acgctgccgt gctggccgcg cggcgcgctc gaagtcgcag ccggccacgg
     1501 gcggggcgcc gccggccgga cgtacgactg ggaccgcatc aaccacgccc gcgaccaggc
     1561 gttcggcctc ctcgcggaaa ccctcaccgg tcaccccatc gaggctgacg aacccgcctc
     1621 cgccaaggcc ctgcaccggg aagtcatcga ccggtggagc gccgagcccg gccggaccgc
     1681 cgccgacgcc gcccacgcgt tccgcactgc cgccgctcgc gccgcacacg ccctgttctg
     1741 acagccaccc gccaccaacc caagtcatcg aaggccagca cgatgaacga gacgacagct
     1801 tcccgcagca ccaccaggac gccgagccgc cgaggagccg ccacccccag ccgggacggc
     1861 gtccaccgac tcagcgtgcc cctcgccccc cggctcagtg caaccgagtt gatccgcgca
     1921 ctcctcgcgg ccccagtgga aaccgacctc tccaccctcg atcccgtaca gacccgctcg
     1981 ctcatcgccg acgtgctcac tcagcacggc tacgacgtgc tcgaccgatc gccgtactac
     2041 ccggagctcg accgccacca ggaggccctc cgcgcagtgc gccgtgcgta cgggccgcga
     2101 ttcctcgacg cccccgacga acaggccgta ctcgctgacc cgctccgcga agtgctcgcc
     2161 gccggaagcg ggaagtcgtg acggcgtcca ccaccgagcc gaccggagca cgggcacgac
     2221 agacgtacta ctggcgggtg cgcaacgcgc ggacgcccca gccgcccatg agcgcggggc
     2281 acgtgtggca catacagccc ggccatcccg gcggcgcgta ctgcgacctc ggccacgagc
     2341 tggagccgcc ctcacaccac accccgaccc tgctttcccg tagccggccg accggccgcc
     2401 gagggtacga gcaggagttc cggggcggct gtctcgcgtg cgactgggaa ggccccgtgt
     2461 actccggcga cgggttcggg gacggcgaca acgaggcggt ggaggacgcc cacgaccact
     2521 gtttccccgg ctggcggaca ctgccgccga tcaccacggt cgaggaccgg tgggccgttc
     2581 cgcggagccg gagccgttgg gctcagctca tcgcccagta cccggcgggc tgggtggacc
     2641 agggcgcccc cgtcgtggcc tggagacggt accgccgcga agctcacgct ccgccgcacg
     2701 cgggacgccc ccgctacgaa ctccgcatta cccggccacc gcgcgaccgg gtccacagcc
     2761 ccgcagatca gggggccctc ttctgatggc cgccgccctc cagatcaggg ccccgccctg
     2821 cgaacccaaa ggtggtttaa ttaccccgcc gtcagcggag cgggcaacct ccggccggcc
     2881 gcgtcccaca ggacgccgcg cacccagaca acagacgacg gccagcgcac aagggcaaca
     2941 aggcgctggc cgtcagcgtt ctctcaccag aaagaacccc accatgctat gtgaccgaca
     3001 ccccgactgt ccccagcccg gcgacatcgc ccagctcacg aggggtaaca gcatcggagc
     3061 cgatcccacc gacaccttcg tcatcgtcga ggacttcccg ccgaccggcc ggcacctcgt
     3121 gctcaacctg cccgtcgacc accccgaccg cgccgactgg gccgccgccg tccccctggc
     3181 cgacatagcc accctcaccc ggctcgaacc ggcgggcagc cgtacgtgga cgccagcccc
     3241 agacccggac gacatccagt aaccgcgccc cgcggtcacg accccgacca agaacaggag
     3301 gcgaccgtgt cccgcaagac cggccgcacg ctctactcgc gcgcggacct gcgcagggtc
     3361 cacggcatca gcgagtcgac ccttcagaac ctctggaccg accgggagaa caacgggcac
     3421 ccgcccgtcg cggacaccat cgacggcgtc atgcactggg acggcgatgc atgggcgacg
     3481 tggcaccacg agcttcagcg gcagcgtgcc gcagccagta ccaccaaccc gccgaagctc
     3541 gacggcgacc ccgaagagat ggtcggcccc gccgaagccg cgaaggtctg cgggttcgcc
     3601 gactccacca cggtctccca ctacgtcaag aacccgcccg aagggtggcc cgagccggac
     3661 ggctgggacg agcttcccac ccggcggcgt ccgaagtgga agcgctggag gctgtggcag
     3721 tacctcgctg accgcaaggg tcgcggtcac gccggcggac ggcccgccgg ccgccgcggg
     3781 ctggcttacc cctaccaggg agacgagcgg ctgaccctcg cacggcaggc catcaaggcg
     3841 aaccctggcg cgaagaacgc cgagctgatc ccgcagctcc aggagcagac ggagaagacc
     3901 tactcccgta cggtctggaa cctgatcctc aagtccgccc gtgagcaccc cgaggagtga
     3961 cctgtgcccg acgcccgctg tccgcgctgc ggcggcccgc tcggtgaacg gcccgcacgt
     4021 tcccggctga ccaccgaccg cgaggtcttc atctgcaccg cgtgcggtac ggacgaagcc
     4081 gtgcgtgaag cccgaggtca ggcgccggtg ccgttcggcg agtggcccct gaatacatag
     4141 ccgccggccg agaagccgca tggccagcat gacgaaggtc cccgctccga tccggagcgg
     4201 ggaccttcgt catgtcgcct cgctgcgcag cttccgcagc cactcactca gcagctcggc
     4261 gttggccctg tccatcagca tgatcatcgc ggtgccgcgt agtgcggagg cgacggtgcg
     4321 gaggtcctca tcgctgtagt cggatgcgac ggcgagcagg tccgcgtcgc tgtggtcgct
     4381 catgcgcagg cccagatcgt tcatccgctc gaccagcatg cggagcgcgc ctgcggtatc
     4441 gacagcctgg cgggtgaggt cagcaagatc gtcgttccgg ttcgccatgt ctccaggatg
     4501 gcctgggcac cccggcccgt gccgtctcca gaggtaacag tccaacagga gatcaggctc
     4561 caggagcctg atcctcagga gcgacgaggc cgatccgagt gcccgaggct tccctcgttg
     4621 atcatgatct tgaatctaga ggaccaaggt atcgtcactc cgtgacgata caatcggcca
     4681 agatgaccga atctgatcgg gtgagagcgg ggggtgagcg ggccggtggg atgggtgacc
     4741 atgatcggcc cctccgacga gcaggttgag taccgcctta ccggcggtca cggctgcggg
     4801 aagtccacca cggtcgacgc ggccctcctc gtcgccgcca tcgaggccaa ggccgaagcg
     4861 gcgggcgcac ccgtcgcatc cctgctcggc tcccgtgaag ccaagcgcgc cttcttccgc
     4921 gcccgcggac tgatccgcag caagggtgcc gcgcggttca ccgggtttga cgccgttgaa
     4981 gtcgcctccg cagccggact cgacgcccgc gacctgtacg gcgaacaggt ccttccccga
     5041 ccggccgccg acggacaggt ggactaccac ctggacgcca gcgaacgccc cttggtgtgg
     5101 atcggcaacg gcctcaacga gttcgacatc acccctggca gcgtccttgc cccggagcac
     5161 ttccaggcgg cccgccgcct tatgcatggc gaggaccctc ggaccgggca gaccctcgtg
     5221 gagcccaagc tcgccatcgc gccggccgcg aagctcccgg ccgctccgct ggctcgtgcg
     5281 atccgccgcg ccgctgccga acgcagcgtg aaccccgtga ccctgctgga ctccaagagg
     5341 aagcaggacg ccttccgtcg gatggagagc cagctcaagc gattcggtga atcgcaccgg
     5401 gtgccggcct ccaccgtgct caagctcgcc gacgccgtcg gcatcgacgc cgtcgccctc
     5461 tacggcgaag acgtgctggg gaaggccgtg gccgccgagg cgggcggcca cctggacgcc
     5521 cgcgcactcc tgcgctccgt cgaggcccgc gccactgaga ccgggcagca gcccgccgac
     5581 ctgttcaccg cagcttccat gaagcgccgg tacgtccaga cggcgggcga gggcgaacgc
     5641 cgccttcgag acctccccat ggccgtacgc gaagccgtcg ccatggccaa ggcggcaggg
     5701 ctcgcgcccg aggacgtgtg ggacgcggag gagatcaagg ccgctctcct cgaagggcga
     5761 gtgcaggtcg ggaacttcgg cgccgacgtc accttggatc tcgcaaagtc gaagtccgcg
     5821 ttcctcgcct acgcgccgga ggagatcgcc gcccaggtgg agggcatcta cacctccgcc
     5881 ggccgcgagt ccatcagtgc cctggagcgg tggaccgcgt acggcatgcg cggtcgccac
     5941 ggtgacggtg acgaggcgga gaccgtgggg acgagcgggt tctccggctg gatgatggtg
     6001 caccgcgccg cccggcccgt ggacggcgcg ccgtacggcg accctcattt ccacctgcac
     6061 ttcaccctgg ccaacatggt caaggggatt gacggcaagt ggtccaccat ggccagcggg
     6121 ggccgcgacc tccaccggca cgcccgggcc acccagtccc tcatgaacgc ccgtatccgg
     6181 agggagctga ccgacaagtt cggcatcagc ttccgccgcg aggagcgaac cggcgcgtgg
     6241 gagatcgcgg cgatccccga ggccacgatc cgcctcttca gcaagcgtga caaccaggtc
     6301 cgggacctgc tgacgaagct gggcatcgac tacgacagcg ccaccacccg cgagcgcaca
     6361 gcggcttcca ccgcgtccaa agccgcgaag aacggagaag ccgcaggagt cgcggacgac
     6421 gtcctgcgcg agtactggca ggccgaaggc cgcgccgccg gtgatgagcc cgaggccatc
     6481 gcggccagcg cgatgcagca ggacagcccg aagcagaacc cgggcttgga cgagctgtgt
     6541 gccacgatct tcgacccgaa gaccggcctg accagccact ccaaggactt cacccacgcc
     6601 gccgccatcg ccgccgtcct ggatgccctc ccgtacggag tcgcggacgc cgaggaggcc
     6661 gaacgcctca ccgactctgt cctccggcac gcggggtacg cggtcaagct caacccgaag
     6721 ggtgcacagc acttcgcgca tgcggaccgg tacacgacgg cggacgtcgt tgccgcggaa
     6781 acgctcatcg tctcggaggc gacaagccgt ctcggcgcgc aggccgccgt cgtcagccgc
     6841 gacacggtcg agatgaccct gtccaccgtc gaagcccagc acggcggcac cttcaagttc
     6901 tccgacgaac agcgcgccgt cctcgaccgg ctgctcaccg ccggacacgg gatcgacgcc
     6961 gtggtgggca tcgccggggc gggcaagacc accatcatgg acaccgcccg gcaggcgtgg
     7021 gaggcccacg gactcgtcgt tgccggcgcc agcacggccg cggtcgccgc cgcgaatctg
     7081 aaggccgaag cggggatcac ctcgcgcacc ctcgcgtcct ggctcaccgg catccgtacg
     7141 ggcggcgccg gcctcaacgg cgttgacgtc ctggtcgtgg acgaggcggc gatgtgcgat
     7201 gaccgcgaca tcgccgaact cctcacccac gcggcgaaga ctggaacgaa ggttgtcggc
     7261 atcggcgacc cgaagcagtt gcactcgccg ggcatcggcg gcagcttcgc tgccgtccac
     7321 caccttgttg gcggcctcac cctcagccaa aacttccggc agaaggacat ggtcgagcgc
     7381 cgggcactgg agctgtggcg cgacgacaac cgagtggaag cgctccgaac cttcgccgga
     7441 acagggcgcg tgcacgccct cgcggacaag gacgccaccc tcgccgcgat gctcaccgtc
     7501 tgggcggaca agcgcgccgc gcacaccgac gaccacaccg ccgtgcagca actcctcatg
     7561 ctcgccgcca ccaacgagat cgtggaggag ctgaatctcg gtgcgcgcgc tctgcgcaag
     7621 gcgagcggca atctcaccgg cccggagcac acgtacgccc tgccgggcgg cggcgagctg
     7681 acgctgtcca tcggtgacca ggtcctcctc cggatcaacg actaccgggg caagaggagc
     7741 cgaggcgaga acgaagacgt gctgaacggc taccgcggga tcgtgcgagc cgtggacgag
     7801 ggacgacgtg tcctggtcga gtggcgcgag aagaccgccg acggacacca cgatgtcgcc
     7861 gaatgggtcg acgccgacta catcgcgcaa ggcggactca gcctcggata cgcgatcact
     7921 ggccacaagt cccagggcct cagtgtgcac gaggccctgg tctacggtcc cggcgcgcag
     7981 gcgaacgcgc tgtacacgat gatgagccgc gacaagaagg agtcccacct cttcctgccg
     8041 ctgtccgtct acgaatccga cgccgaccgt gcacgcggcg gtaccgcgct caccgagcag
     8101 gaacagcttg accgcgctgt tgccggcctc atccgcgaga tcgagagcgg aaccgaggag
     8161 cgcatgatcc tcaccgaact cccgaaggac atggtccccg cccacgttcg tcaggccgta
     8221 gccgatctac cgaccccgta cgcttccgga accggcaccc cgcacgaggc ggacgccgcc
     8281 catgacgcgc cggagtccga tgaccggcgt accgcggaca ccactgagcg gcccgcgacg
     8341 ccgaccacac ttccgggacc ggcgccgagg gctgaccgct cgtacgctca cctcagcagc
     8401 gcagccctgc gcgacgcggc gcgcaaggcc gtcacggccg cgcgcgccac gaggacggcg
     8461 gcagagaagg cggaggccac cgcggaccgc gccgcacagc aggccgccgc cgggacaggg
     8521 ccgaacgcgc tcgcgttcaa ccgtcgacac caggccattg ccgaccgggc cgtggcaatc
     8581 cacgaactcc gagcactggg cggcaccatc ggcgaacaca ctgctcgact gcgcgacacg
     8641 caggagcgca tcgatggtct tgaccagcag ttggccgcca ctggtcgatt cgggcgcccg
     8701 gtgctgcgga gggacgcgcg ggctgcggtc gaggcggacc gcatggaact gcttcgttcg
     8761 tacgaggaga ccgggcgcga gctggagcag atgaacaagc ggctcgacga ggttgccgag
     8821 caggctggac ccgtcagcga acacgaagcc gtgctgaccg aagcggatat gccgcagcag
     8881 gacaaggccg cgctcctgcg acgtgccaag gagaaggaca accaagcagc gaagcgtctc
     8941 caggcggagg cagctaaggc acgcagtact gctcgtggcg ccgaccagcg ggcggccggc
     9001 ctccaagagg agatggcacg gcgaactcaa cgtgggctcc agcacgccga cgccgaggag
     9061 tccgcgtcgc cgtccgcccc gaagcccgag tcctcgtatg ccgaccgcac caccgcggat
     9121 ttcccgcagc agtatccgcc ttcagaggcc gtacaggacg caccgtccgt gtagaagagg
     9181 ctcggggcgc ttacgcctcc gtgacgaaga ctgcgttgtc cggcatccgg tcacgaaaac
     9241 tctccgggat ggtgcccatc agccaaagtc ggtgtgtcgc gtgcacggcg cccgttggat
     9301 cgttcaacag gacgtagtgg cgcacctcga cccccgcgta gccgatctcg ggcgggaagc
     9361 cctgctcctc ggtccacgtc aggtagtggc ggcctccgat ccgcagcacg cgacgaccgt
     9421 ccggatctcg atccccgagc atcgcgtagc cccagcacgt cagccagaaa tcacacgagc
     9481 tgcacacccg gtacgcagcc atccgcgtgc cgacaccccg gatctcctga ttgttcccct
     9541 tgctcgggca caacttgcac tggaacaact cgtacccctc gggtacgcgc gcccgcctca
     9601 cgcgccgtaa gaggcggacc tacgccggat gtgcttgcac ctcacacctc gttcgacatc
     9661 ctgaagcgag ggtttgcggg acgccccgca gtcgatgcat tcgctcggcc agggcatcga
     9721 gcgggcaccg gggtaaggtc ccttcggttc gtagccggcc gcacgcatca cctcctcggc
     9781 ctcctgttca tcggcggtca cctcggtggt gggcgtgggc ccggagacgg gcggcgggag
     9841 ctcgaagctc tgggtgtgtc ccccgaacag caatccgagg ctcacccatc gctgtgccgc
     9901 gatggaacgg tcatggcaag tcctatctcg cacaactacg ggtcgcgtcg cctgggctta
     9961 tacctggtgg ccccggcgat ttgcacggct agcggccgac ctatgtcccg ctctccccgt
    10021 ggaggatcgc cgccctggct gcccaggcaa gtacgctctg ggcccgcatg gacaggccga
    10081 gccggttcca gtggaagatc acgtggtagc tgagcacctg cctcagcccg cggtcgagcg
    10141 ttccttcctg gacggcgtgg ccgagtgcct gcccggcact gcggaaggcg gcggcacact
    10201 cggcgacagg ctccagcggc ccgccggggc gcaccatggt gtcgctattg gcgaggagca
    10261 ggggccgaat gccctgggcg agggcgttga gtcgggccgc cgggacatcg ccgagggccg
    10321 agcggtgttc gatcgtgatg acgcggtccc agacgtcgcc ctgctcgtac cactccagct
    10381 tcgccgcgcg catcatgtgc gtgcagagga ggacggacag ttcccgcagc ccgacggtcg
    10441 ggctgtcgtg ttgccgcagc cgctgcgctt cccggctgtc ggcgatgaac agggcgtgcg
    10501 cggccgtcat gctggcctcg cccccgaacg ctgcggtttc aggctcgtag atgccgggcc
    10561 accagcgcac gaggtggccg tcggccacaa ggcggtgcaa gccgagtcgg tccaggccct
    10621 ccgcggcgcc gagctgggcg ccgatccccg gccggacgcg gagacgcagg cgccagcagg
    10681 ggtgcttcct ggtgtaccac cagccgccga tgacgccggc ggtctccgcc tcctgtagca
    10741 ggggcaggac gtgcgcggtg aaggtctcgt cggctttcgc ccagtcggtg aagtggaggt
    10801 acacctgcca ccagtcgacc gtggaggtgt gccgggccag ggcctcccga ccggcctggt
    10861 cgtagaccgc cacggcgtcg gacaggatcg tcggctccat cccgtactgg gctgcgacct
    10921 cggggatcgg caggccggtg agggcggcgg cgaccgcacg ctcgatcggg ctcggctccg
    10981 tcaagatcag ttgatcaaga gacatgcgtc ccatccggtg atcggggcct gctgtgaggc
    11041 gtgggtggtc agggcgagcg cggtgccggc gtcaccgttg atcagaccgg gcccggaaag
    11101 gccgggctgg gcgttcgccg cgagggtgtc gccgaggccc ttcggaaggg tctgaaggcg
    11161 agggtcgaga gcatcggcgg cggcgcgggc ggcggtctgg tagatgcctg cccagccgtg
    11221 gcacagaccg gagtcggtga catgcgcgag ctgttcgggg tcggtcaggg cgcgatacag
    11281 ggcgtcctcg tagaacttct ggagcgtagg ggaacggagg gcaagcccgg cgagttgccc
    11341 ggcccgcgcg atgcccgtcg tgccgtagca ccagctcgga cgtgcgggcg catcgtggtg
    11401 gggccgtccg cggtcaaggt cgcgccgcga gatgtgctcg ggccaccaag ggccggcggg
    11461 cccggtctgg caccacatat cgaggtgtgc gcagatggtc cacatggcgt cttggtggcc
    11521 gctgacggtg atgccacggc ggagggcttg ggccagcagg aggagcgggc cggtgatgcc
    11581 gtgggccacg ccgaagttgc cgtgaccgcc cgggaagtgg ggggagtcac cgcgggccgg
    11641 atcgtacggg acccaccagc ccggcaggcc gcggccgtcg ggggcgaggg ggcgggtcag
    11701 ggcgacgagg tacttcagga ctcgttccag tggcagccct tctgggtcgg tccgcaggag
    11761 gtacgcgccg atgccagtga ggccgtagaa gaggtcgtac tcggagaacg tgggcaggta
    11821 ccccttgcgg atgcgggtga gcgcggcgtc cacgcggcgg tgggtcaggt cgatgatgtg
    11881 ctggtgcagg gtccgccacg ccggttcgta caggtgctgg aaggacggag ggacggtggt
    11941 gaggacgaag ccgagggccg gggcgccgag gaacagcccc gcggtgtcgg ccgcgctgat
    12001 gtgcccggcc gctgcggcgg tgatccaccg gtgggcgggg cgccaggagc cgccgtgacg
    12061 gctggccatc tcgatgtgca gcaggctgat tccggcggcg ccgtcggcga gggactgcac
    12121 cgcccacggc tcgtccgggg gcggaggagc gggttgtgcg aggtgggcgg tgtactgctc
    12181 caggattgcc gcggtggtgg cggccggcgc ggtcatcggg ccgccatccg gtgctggagg
    12241 gctgcggttc gtacgagccg gatcgtggtc tcctcggcgc gcggatcgac gcccagggct
    12301 cggacgtggt gctggtgcag gagcgaccgg gcgacgtcga gcggatcacg ctggccggtc
    12361 aaggtcttcc ggtaggcgtc cacggcggcg gcgcgagccc gccatgcttc ggcgaccgca
    12421 gggccgccgg ggagggccgc gagcacggag gcgccgttcg gcgcggcgag ttcgaggacc
    12481 tgggtacgca gggcccggct cagtcgtccc gtgccttggg ggaggttgcg caccaaccac
    12541 tcttcggccg ccgcggtgtc cggcgccagg ggggtgacga ggtgcagggc gctggccgcg
    12601 gcgagggcct gcggggcgag tgcgtcggtg cgctcggtga gctggatctg cgcgagggcg
    12661 gcggcggagt ccgcggcgaa cacctggtgc gcggtgtcca tggccgcctc gccgccgaag
    12721 cgcccggtct gcggctggta gggagccagg acgagcccgg ccgccagacc ggtcccgtgc
    12781 aggctgtccg cccacctgcg gacgtgttgg gcggcggccc cgtatgcgtc tggcggcagg
    12841 tgcagcgtga agttgaggtg ctggtcggca tccgggcggg ccatctcccg gtgccgggtg
    12901 aaccaccaga gtggcggggt gtcgccgaac gcggcgagga ggctgggcag gtggcggctc
    12961 aggatctcgt cgtagcggcg cgggtgggcg tggagctgcg cgagcaggac gtcgccgtcg
    13021 cccggaagat gccgcccggc ggctagcgcc gtggcggggc gcgcccgggg cacatcggcg
    13081 gtgtccggct ccgaccggcc aagggagagc cagatctcgt gtgcccgccc gatccagccg
    13141 tgggcgtctg cgtcagggac ctcgcgcagc tccaggcgcc gggcgttgtc gaggtgggcg
    13201 cgcagcgccc ggcggtgaac cgggtgggac aggtcgaggg ggaggcgctg gtcgtactcg
    13261 atgatggcga cctgcatcgg gacccgcagc cggccccgcc agacggcgaa ggcgttctcc
    13321 cactcctcgg tcgaggcttt gcggccgggc aggtcgtcgg ccatcagcag ccatcgggcc
    13381 tgcgtgagga tggtgcggcg gtagcgcacc ctggggagga acgggagccg ggagccggcg
    13441 ccgaagtcga acggcttgta ggcggcgaac cgcccgtggg ccacttcggc gaggaaccgg
    13501 gccagcggcg gggtctgcgt cccaccttcc agggcgtgca ggacccgcac gtcgatgcgc
    13561 tggccggtgg agagctgcac gaggtggaag ctgcgcgggt ccgcggtgac ggcgatgtcg
    13621 gcgagcggga tcgtcgcctc gtccgtctcc tggtgtccgg acagctcgat gacgtgcggc
    13681 agcagccgcg gcgtacgggt gacgttctcg ttgcggtggc ggcgcggagg gaacacgagc
    13741 tgcgccgtga ggccgtccgg cgccccgcga tacgtggcgg cgagcgcgtc ctgatgctgg
    13801 ggcgggagga cgtgggcgaa ccggccggcc atgctgctgc cggggcgggg gaccgcggtg
    13861 aggaggacgt cgaaggtgcc gctggacagt gcccgggtgc tgggtgagtg gacctcgaag
    13921 gcgacctcca cccggggcac gaacaaccgc tcgtccttcc cggccgcctt ctccaaggcg
    13981 tcgaccatgt catccgtcag ccgcagttca ctgccgccgt ccaggaggac ctgttgcatc
    14041 agcgcgagca gcagttcgtc gcggtcggtg cgcaccttca gggcggcgcc gcgttcggag
    14101 ccgacgtatc cggcgggcag gcccaggccg ctgtcggcga ccaggtccat caccggcacc
    14161 agggcgccga cgccgtaccg ggcccggaag cggcggtggt agtcgcgcca gtgctggtag
    14221 ccgtagggct gcggggtggt ccggtagagg gcggacacgg ctgcttgcac ttccgcgatc
    14281 acggcctgcg ggagctgggt ctcgcagtcg agggcggtgt cgatgagcag cggtgtcggg
    14341 gtgacggggg tgagggcgcg catccgcgcg gcgacggcgc tcacgctggt gtcggagagc
    14401 gtcggctggt gggcggacag ctcgtcgcgc agggcgtaca gctcgtggac caggtcccgc
    14461 acctccggga tgctgtctgc ctggagccgg tccagttcgc ggcacaggtg ctggaaggcg
    14521 tccacggtgg tcatgggcgc ccagaggctg gcgatgagga attgctgctc gaccaggctg
    14581 gtgagaaggg cgtcgatctt ctccggtgtg gcctgcggga agcggtcgcg caggtggccg
    14641 tggaggttgc cgtaggggat gggggtgcgg gccgcgtcca tggcggcggc caccggccgg
    14701 gcgttgcgga cggatatctc gaccggggcc aggaggacgg cgtggccgtc ggagggcggg
    14761 cccggcgcca cgagccggtc accgcggacg cgggcggcgt tgttggcgac gagcggtaac
    14821 cgcttcagca acgcgggggt gccctggagt cggagcacca agtcggtgac ccattcggcg
    14881 tccggccgga tcatcgcgcg gtgcttgtcg cgccaccgcg cgctcgcccg gggcccgacg
    14941 gacaccgggg cggtgccggc gaacaggccg agcggggtcg gccggtgctg ccaccgcagg
    15001 aggtaggaga cggccgagag cgcggtgcgg cggacgtgac ggggctcggt ccgccggccc
    15061 tggacgacgg cctcgatggc gtcggacagg acgggggtgg ccagctccag cgcgctgcgg
    15121 aagtcctcgc gctgccagat gcggttcagc catccgcggg tgacggccac gttgtccagg
    15181 ttgagggtac gggggatgtc tgccggcccg gggctggtcg tggcgcgcag catcgcaacg
    15241 ccttgccaca ggtatccggc ggctgctcgg gaagccatga ggcccttcca tgaggcggcg
    15301 cggggagggg agaggggcct gtgggccggg cgaagcgctt cgcccggccc acaggtgagg
    15361 ggttggcctg atcaggccgg gtcctcggtg aaggaaccgc aggcggaggc accggtcgcg
    15421 caggtggtgc cgcagccgtc gcccgtggag cacatgaggt ggccgtacga gtgctcggcg
    15481 atgacgacct tcacgtccag gggcgcgaag tcgtcgtcca ggtccgccga cggcgcgggc
    15541 gcgaccgggg gcggggcgag agtggcgctc gtcatgatgt gcccttcttc ttgttggggt
    15601 ggtgcgggat gacctggctc ccggtgttac gccgagggcc aggagagcga gatccgggtg
    15661 tgcaccttgt cgatgacccg gtcggccggg atctgctcat cgggggtgct ggccggatag
    15721 acccggatga ccgggctggg gccgccgcgc cggttggcct cccagtcgcg gagcacgtca
    15781 gcgatcttgt cggcgaactg ctccgcgtgc gggccgaggg cgtgcacgcc gtactccagg
    15841 tgcttgttgt cctcggtgcg gcgggtgacg aggtaggcga aggtgtcgtc ctcgacggcc
    15901 gcgagggcga accgcttgtt cacgggggcg accaggcccg tgtccgagtt ctcatcgacg
    15961 gccatcgtgc agaagcccgg cagactgatc gccatcgcca tctggagggt gtcgatgagt
    16021 tcctggacgc ggacggtgac accggtccac agttcgtggc gcgggaacgt gacggcgttg
    16081 tcgagtcggt gcgggtcggc cggcaggccg tcatcgaact tcagcccgat ctccggggtg
    16141 ccgttgacga ggaggagttc ttcccggtgg gcggtcgagc cctgcatcgg gacgaagccg
    16201 cagatacgcg ccgactcgct ctccaggtag gtgccgtgct cgcccgtgac ctgggtgaaa
    16261 gcgaccgacc gggtcaggcc gcgcatccgc agcgggacga cgagccgacc accctgcttg
    16321 agctgcgcgg tccaggccgg ggagatgtcc caagccccgg cggtcaccat cacgacgtcg
    16381 acctcgccga ggtccggaat cggctcggcg gcatcggcgg tgacgacgcg caccctgtcg
    16441 tagccgtgct cgtccaggag ccggcgcgcg cggtcggtga cgacggggtc gatgtccacg
    16501 gtgacgactt caccgccctc accgacgagc tcggcgaggt aggccgcatt cagcccgccc
    16561 gagccgatct ccaggacccg catcccgggc ttcacctgag cctgctccag catcatggcc
    16621 tggatctgcg gcgcggagac ggagctgagc tgcacaccgt gctcgtccgt cttggtgatc
    16681 acggcggcgt acgtgtcgta cgccttgtcc agcggggtgt cgggagtgaa ctcgtgccgg
    16741 ggcaccttgc gcatcacggc ttcgacctcc ggggaggaga tgttgccgtc cgcgcacagc
    16801 tcgtccacca ccttgttccg caggcgggtc gcctcgtcgg gatcgacggt cgtgttcgtc
    16861 atggacttcc ttcggtcgtt cgtgttcggg ggaggtaggt cggcaccgcg tgccggtggg
    16921 ccgggaggtt atcggcgaac gtcctccgtt cttgccggac cgccgaaggt tggcggtttc
    16981 gtgccggacg gcgcgcgagg gctcggcgcc ggtggtgagc cgcccggcgg ccctgtccgt
    17041 atcactcagg accaccgggc ggccgtctag gcggcaggca caagatcgtc cagtttgacg
    17101 acctcgtagt cccgcagttc gcgtacgagc tgagaggcga ggaaccaacc gatctggggg
    17161 tggctgtaag ggaggggcct gtctgtgccc gagagggctt ggatgccgtt gggaccgtac
    17221 tggtacgccg tgccgatcac gccgtagagc ggaaatcgcc tggcgaggag ggctacgtgc
    17281 cccttgcgcc tgagccgggg gcaccggctc gccgccatcc gggcgtgcgc gagacagacc
    17341 ggcggctgtg ccgttttcac gggaccggtg tagtcgaggt catcggctgt ctccaggaag
    17401 aggatgccgt cgctgcgctt caactggacc gtgcacacct ggcaccggag cagagccatt
    17461 gtcgagcgct ggcgaagggg atggaccagc cgccacctcg gggttccggt gggcattccg
    17521 tcgttaccga gcgacattga gtaccgggcc cacaggacgc ctcgcaggtc ccggtcgggc
    17581 ggttcctcgt ccacgtacgc cagccgtggg cggcgatctg gaccaaggcg tacacgcagg
    17641 ttgaggaggg attccgcttc ctcgccctcg cgggcggtga tatacgggac gatcaggtcg
    17701 gctgcagtgg tcatgccgcg cctcctacgg gggccgccag ggaccggcgc ggcgcgacga
    17761 tcgtgccgtt gggcagcagt tcgccggtgt cctcgactat gtccatcagc cttgcgggtg
    17821 tctttgatgt ccaactcgct gccatgaagg ggcctttcgg tgctacatgg acgggttctg
    17881 ttcgcctgtc catgtcgttc tggggtgtgg tgtgtcgttc gcagtgcaga ggctgcggtt
    17941 gtccgaggac ggtccggtct cgtacaccgt ggtgggggac gacggcttgc ccgtcgatga
    18001 cgtggaggac ttcctcgcgt acctgacggc gaggggtgca tcgccgaaca cggtccaggg
    18061 ctacgcctac gacctgcgcg acttcttcgt ctggctgggt caggtgggct tggacttccg
    18121 gcgtgtgcgg ctggaggtgg tcgcccagtt cttcgattgg ctgcgccgtc cgaagcctgc
    18181 ccgagcgccg gaggttttcg tgctgccggg tgtcggccag gcgctggaga acaccacgct
    18241 gcagcggaag cgggccgcgc tcgcgtcgtt ctaccggttc cacgccaggc gggatgagag
    18301 cgtgcccgcg ctgctgggaa acctgctggc caggcagccg acaggctcct acacaccgat
    18361 gctggcgcac acccagcgag ggggcgaggt cgagtacagc ccgatccgca tccacgccca
    18421 ccgcaagccg ccccggacgc tgacggatga cgaggtccgg cggctgatgg gcgcctgcaa
    18481 caggcgccgg gaccggttcc tgatcgcgct cctggacgag gcggggctgc ggatcagcga
    18541 ggcactgggc ctgcggcacg ctgacttgaa cctccgcaag ggcgaggtgc acgtcgttcc
    18601 gcgcgagaac aacgcgaacc atgcccgggt caagggcatg aagggccgga tcatcccggt
    18661 gcgtccggag ctgttcgacc gctacgccgt ctacatggag agcgagtacg ggacgctgga
    18721 ctgcgacttc gtgttcgcca acctcttccg cgcgccgatt ggctccccga tgacccgggc
    18781 gaacgtcaac gagttggtcg agcggctgca gaagcggacc gggatcgcgc acttctcgcc
    18841 gcatgtctgc cggcacacct acgccacacg actgctgcgg gcagaggtgc cgatcgaggt
    18901 cgtggccgaa ctccttggtc acgccagccc gcagaccacc gccgagatct acagccatct
    18961 cgatgtcgag gatcatcgcc gggtactcct gtcggccggg atcatcaagg acagggcacc
    19021 gacccggtga acacgccccg cgcgagagca ggctccgacg gcctgctggc caggctgatg
    19081 gagacggtgc gcccggagtt ccgggccgag gtgttctgtc cgccgcggga cagcccggtg
    19141 ttcttccccg gcgagtgccg cattccggcc tgcccgacga cgctgaccat gggccggctg
    19201 aagctgtgcc gcacccacca ccaccgctgg gcggcggcgg gacgaccagc cgatctggac
    19261 gggtggttcg ctcaggagga tgcgcgactg cgcgaacgac gccaggtctc ggcctgccgg
    19321 gtctccgggt gcaatcgggc ccgagccgcc cacggtctgt gtcaccgcca cgcctcgcgg
    19381 tggaaccacg ccggacgccc acccctcgaa tcctggctgg gacggaccct ctatcaacct
    19441 ccgcgcaaac cctggtccgc cgagcggacc tgcgacttcc ccgactgccc gcgctggacc
    19501 gacagcaccg acgctccgct gtgtcacacc caccacaacc ggtggcgcaa gcacggccga
    19561 ccgaccctcg acacctggta cgacgacctc gctcaccgcg gagacccgaa gatccgcctg
    19621 gaccagctga cccccgccct gcgcctggag ttccagttcg gtctgcaaca ccggctcgac
    19681 gaaggactgc gcttcacccc cgcccgcgac gtccgccgcg cggtcacctg ggcctgcgag
    19741 gcacccatca ccagcctcct cgactgggac gagagcacct ggcgcgacca cgtcgccccg
    19801 ctcggacccg gcgggaaacg ccacggccac aacgtggtgg ccttccgctt catcgcggac
    19861 acccgcttcg ccctgaagca cctgctcatc gccgatgatc catgggctga ccagtacccg
    19921 cgcgacgtct gggacctgcg gcacttcgcc ctggccgaag gagagacgcg ctacctccgc
    19981 ttcggcccca taccccagcc ctggctgcgc gagctggtca aacgatggtg ccgctggcgc
    20041 atcagtacga acatcagcgt caacaccgtc gcgcagaacc tgcgctccct gacccatctc
    20101 tccgggcatc tgccaccgca cgccgcgccg gccgacctga cgcgcgccag gatcgagacg
    20161 tggctcgccg ccctggccgt cgactacccg gacgtgttca cccgccgggc caccgttaac
    20221 tcgctgggcc gcttcgtcgc cgacgcccgc gcccacgact ggcagccggt cctgccgcgc
    20281 gacgcgatca tctacaacga cgctccgcca ccgccgccgg ccaagccccg gtggatctcc
    20341 gaacacctga tgcggcagat ggagaacccc gagaacctgg cgttgatctc caccgacgac
    20401 ctccgcctca tggtcccctt gctgatctcc tgcggcctgc ggatgaagga cgcccggcgc
    20461 ctgcggttcg actgcgtcac ccacgacgac accggcgccc cctacctgac ctgggtcaac
    20521 cacaagatcc acggccgcat cgcgttcttc cccatcagcc aggccctggc cgacgagatc
    20581 gccgcacaac aaaagcgcgt ccaagcccgc ttccctgccg gaagccgctt cctgttcccc
    20641 ggctggatgg ccaacctcaa cggcagcaag gccgtctcgg acacctggtg ccgcgaacag
    20701 atggagacct ggctggagcg catccgcctc atcgacgagc acggccgccc agctcgcgtg
    20761 accttccacc agttccgcca cacgctgggc acccggctga tcaacgccaa cgtcccgcag
    20821 cacatcgtcc agcaactgct cgaccacatg tcgccgcaga tgacggccat ctacgcccgg
    20881 ctgcaccaga agaccctgcg cgagcactgg gagaaatccc tcaagatcaa cgccgaaggc
    20941 gaagccgtcg ccctgcccgc ggaccacccg cttgccgatg cgacctggat gcggctgtcc
    21001 ctggtccgcg ccaaggtcag tctccccaac ggctactgcg gagccccgat ccagacggac
    21061 tgcgagtacg cgaacccttg cctggactgc cgcttcttca tcaccaccgg cgacttcctc
    21121 gaccagcacc gacgccagcg cgaagagacc cgcaagctca tcggcgacgc cgaaaaagcc
    21181 ggactgtcgc gcatcgtcga gaagaacacc cgcacgctcg gcaagctcga caccatcatc
    21241 gacgccctgg aacaggccgg cccgcagcag atcgtggccg gcgggaaggt gaccgatctc
    21301 gatgccaccg gctgacaacg cccgcttcct cgtcgaagcc tcgaagacac gcagccggca
    21361 ggcacgcgag cgcgccgaag aggccatcaa gacggcagcc cggcgcagcg aacggcccac
    21421 cgtcgtcggc atcgcgaacg cggccggcgt ctccaggtcc tggctataca cgcagaccga
    21481 cctcatcacc gcgatcaacc agctccagca gcgagccccg gcaccccacc gcaacactcg
    21541 gcacgctgcc agtgatgcct ccctgcaacg caggctggag accgcgctcg aacgcaaccg
    21601 gcaactccgc gaccaggtcg ccgacctcac ccgaaaactg gagaacgccc acggcgagat
    21661 ccgccgtctc cgcaccctgg cccagccacc cgcggccacc gtccttggcc cccgctgagc
    21721 ccacagtccg accgctgcca ctgcccgacg aagacatgtc caccaggcaa agtccctgct
    21781 cagcggcact atcagcgcca gagatcgaca taacctcgaa gagcagcacc tggttgcaca
    21841 acaggctcca gccctgttcc gggtggtacg cgatgggccg cgcggcatcc ctgtcaggag
    21901 cctcagccgt ggggcacggc ggggtgtgcg cgcacatggt gctcgtcctc tcaggtgcgg
    21961 agcgggaagt caggccctct tcggcctcta cggggccgtg ggggacggtt cggagatggc
    22021 cgaagaggga gtcggtaggt gttgccgtac gaactcggcg atggcggcct cgctgtatcc
    22081 gtagaaccgg ccgaagaccg cgtcgtcctc ccaccactcg ggagcgggct cgccccactc
    22141 gaccgtgtga caggtgtccc ggtacggcga ccaccggacg cggaggtccg ggaacccggg
    22201 ccggtccgcg aggaggccgc gcgtcgcgat cgccagtgac agcagctcga aggacatgta
    22261 accgccgcgg cgagggccgc cgaccggtac ggcgagcagg ggcgcccgga aaactcgcac
    22321 ggcaacagcg caatcgagaa ctgctggctc ggcgaggcgg tcacggaagt attcgaagtc
    22381 gtacgcctcc tcggccgggc gaagcgagac ggtgatggcg cgcgccggcc tcatagcggt
    22441 gctcatcact cgatcagccc cttcacgatg ccgacttcgt ccaggcgctg ggcgagttgc
    22501 agggtgaccc gcccgagcct gcgtaggtgc ccgagggcct gccatgggtc gccgggcagc
    22561 tcctcggaac gcagcacgcg ggcctgttcg atcagggccg cgatgtccgg gtgcttcttg
    22621 tccgcctcgt cgcgcagacc tcggtgcacg agctgcatga gggcaccgcg gaaccgttgg
    22681 gcgagttcgt cggcgtcgtc gtactcgggc ggcgccacgg cccgcttgcg tccggttgac
    22741 ccggcggcat ggtggctgac ctcgccgttg aggagcgcgt ccacatcttc gaacacggcg
    22801 ctccagtcca ccggctccca ctcgcgtacg gcgctcaggt accgctcaat ggccgccctg
    22861 tcgagcggtg ccgtccaagg atgcgtgggg acggaggggt ccttgactcg gatcggaatc
    22921 cgctcggccc gctcgctttg gtgctgtacc gcggtgctcg tcatcggctc gccgccaaac
    22981 tcaggtcgca ccatgtcgtg gctccgtcgt catcgacacc ccaggcccct cgtttgctgt
    23041 gtgcgatcgc tgtgacgagg gccaggccgc gaccgtgctc gtcttgatcg ccggggtgct
    23101 gcacggtcgg acgacgtccg gagacgccgt cgtgcacgcg gatacggagg aggtcgtctt
    23161 cgagatcgag ggtgaggcga acgcggcggc caccgctgtg gaggatggcg ttggtgacca
    23221 gctccgagac gaccagggtc gcttcctcag cgacgcagtc cagaccgtac gagcgaagtc
    23281 gctcccgggt cacgcgcctc atggcacgga cccggagttc gtcttcacgt ggggggactt
    23341 cgcccggcgc gtgctcggtg atgggaaagt cctccctcac caggcagccg tcgcgaagta
    23401 cggtcgggcg ctgcggcgcc ggggccgtca ccgctccgtt ccgatctgcg atgtccggtc
    23461 gtgccgggcg tccggatcgt cgatcgagga gaaggctccc gtccggcgcc gctgccccgg
    23521 gacgcgccgg agcagtccgg ccagggcagg cagaggggtg accgaggcgt cggccaggtt
    23581 gcggcggcgg tggcggtctc cgggagtccg tgtggtcatc gggcatcccc ttccgcgatc
    23641 gggaagaggg caccgagctt gctgtacaga gcgaccgctt cgtcagccgt caggaccagc
    23701 gggacagtcg cgggctccgc ggccccctcg tgcaggtcga ggggcaccgc gaaacggccg
    23761 gcctccgtcg gcgcgacctc agcctcactg gcaaggcgga gatggcgctt gatgggcggt
    23821 aaaggcgccg cgccaggtac cgtctgagcg tgacttctcg tcatagcccg taaaggtagg
    23881 gcgacttggg cgccttaccc ctgagaaaaa atcagggctg agtaacactc agggttggca
    23941 tatgctcacg cagcgaggcc gatatggacg gcgaccgcgc gtaggtcgtc gcgccacatc
    24001 ggcttttcgc gcttcagcag gtcggccacc gcctccctga ccagcggaga gaacacgatc
    24061 tcctccggtg actgcttcag cagcttgccg aggatgtgga cggtcgcgta gtcgtcgcgc
    24121 tggatgcggt tgaggttcat cacctcgatc aggtaccggg ttcgccgttc gagcggaact
    24181 tcggggttga cctggacgtg gtcagcggcg cggagcgctt cgctggtgtc gccctcctcc
    24241 gccttcaggt gcacctcgtg catggcgaag ttggttggcc cgaagcacgt gtgccaatgg
    24301 ttgaggtccg agccgacgcg ctgcacggct tgttctgccc cgtggtacag gtcccaggcc
    24361 ctcggaccct tggtcgcacg gacggcggcg acggcgcctt gcaggtgcag cgcgccgtac
    24421 gcggaccagt gctcagggct ggagtcctcg tttggccggc actgcgcgat ggtctgctgg
    24481 gccagctcgt agctgtcgtc cacgtctcca gcggaggtga ggacgcatgc caggttccag
    24541 gccgcagctg caaggagggc cgggtcgcct gcgttgtccg cgagggcgag gccgcggtcg
    24601 gctgcgacgc gcgccagcgt cggttcgccg acgcggcgca gccagatctg gtgcaggccg
    24661 tagaggctga tgagctgccg aaggacggtg ctctcctgct cagccggggc gtcgcgcagg
    24721 gcggcgtgcc cctgccgcag cagaatgggc agtcgggcgc ctacgtcgcg gtaccggtcg
    24781 tcggcctgcg tctcgtagac cttccaggcg tccgtgacgg acgactcgaa gtcgtccgcg
    24841 ctgatcgatc cgatacgcag cggaagcagc gacgcgggca gggacagggc ctgtcggatg
    24901 agcgggacgt tctcgtgctc ggtcccgccg gtggcgattc cggacacata gccgccggtc
    24961 agatcttcca ggctgcaccg cagggcctta ctgagcgcga tcaggatcgg gagccggtcc
    25021 aggggcatcc ggtcgttctc gatcttgtag acccagttct ctgacctgcc gataaggtct
    25081 cccagcatct tctgggacaa gccccggcgc tcacgccacc acttgatcct ctgcccgatg
    25141 ctgaacaact ctccgtcata cgccatgggt tgaccattcg tcgtagtgga cagggcactc
    25201 gtgtcaagcg tatgcccgcg cgcgtcaggc aggggcgata ctggtggcct ctccctccgg
    25261 gagggcactc aacggtcc
//
