LOCUS       NZ_LIYH01000004        21197 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold4, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000004
VERSION     NZ_LIYH01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 931391)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 931391)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 543873
            Orig. end                         :: 565070
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21197
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="amglyccycl"
                     /region_number="5"
                     /rules="(DOIS or ValA or salQ or strH or strK1 or strK2 or
                     NeoL or SpcFG or SpcDK_glyc)"
                     /tool="antismash"
     cand_cluster    1..21197
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21197
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11197](+)"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11197
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(DOIS or ValA or salQ or strH or strK1 or
                     strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="1"
     gene            complement(471..1901)
                     /locus_tag="AMK26_RS19480"
                     /old_locus_tag="AMK26_19205"
     CDS             complement(471..1901)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04215.1"
                     /locus_tag="AMK26_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19205"
                     /product="collagen-binding domain-containing protein"
                     /protein_id="WP_079277685.1"
                     /transl_table=11
                     /translation="MRTTGLAAVIPAVVCGLCAVSPGTPAAGAHETSTVIGNPMAGNHG
                     FGVVTRRDARLGGTESGSAVAVGGDLALGSRYTVAPRGAGGFVAPGDARPTALLVDGAV
                     DFPGSAVDAVLRVAGDRYVKVGDLGGGARTTGMNGTPVRTRLVAAGAGYGTTPRVELTT
                     AQPPPSVGPARGLIDFGTLFAGHRQRADALARCRATVTPRDAGGATVRVRLADDRTNVL
                     RLTGARLAGIRVLAFENRPTAARPLVIVVDTTAEGGELSWRTPTMAGVGGEGAPYILWT
                     FADATDIALTAGDTLTGSVYAPRAELTDGSPADIEGDVVVRALKAGPLAGGIRNAPFAA
                     EPSCDDDPAAAPAHSPSPALSPPGAPGPEPKPEPGPKREPDAEPEPEPEPAVPGPEPEP
                     AASEAVTDARPPSEPSPAEPSPAPRGEPRAERAEGAEMADTGARPKLWLLGAGAVLLVT
                     TGAVLTRASRRDHRDPGE"
     gene            2035..3975
                     /locus_tag="AMK26_RS19485"
                     /old_locus_tag="AMK26_19210"
     CDS             2035..3975
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662467.1"
                     /locus_tag="AMK26_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19210"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073756293.1"
                     /transl_table=11
                     /translation="MRDKKLFRRAWRAEPPVSDSERELFGGALRYDFGWVKHEYAVLDL
                     KPLAAVRALPRLIGSTLRLSWESDRRALLTVGLTEIGQGIAQAVGLLLTNQVLQALFAA
                     GTTTERLRAALPALIAAGVLAVVNAVLASLSTAGTGRLEPKVERLATEKYLHRAAGVEL
                     EAIEDGAFRKLLDSAQFGALAARNMIGACVGALNGVFTIVAAAGVLTVLHPALLPLLVL
                     IALPRGWGAMHVAQRRYASRMNWIEHERAARLVNNLITSRESAQEIRVHQVGRYLLDKF
                     HDMAETSEAEQTRLADGRAVTELLAAAFSGVAALLTYAALGALLVTGRMDIAMAGTAAL
                     AVRTGSASLSALITHINTLHEESLYVRDLDRFTAAAESRAIPSGGTPVPDFPEKITLEN
                     VTFRYPDRDEPALRGVSLTITAGSVVALVGANGSGKSTLVKILAGLHRPGEGCVLWGDT
                     DLADADRLDVFRHVAVLDQDFQRWPFTLHTNIRIGQPHAAPHAGRVERAAAYSGADRLG
                     ATLPRGYDTLLARQFRHGSELSGGQWQTVGQARLRYREAGLVIADEPTSALDPEAEIES
                     FQRIRALTGEGRTVVLVSHRMAGIQSADVIHVLHEGRLVESGSHRELMDRPGSRYRRMY
                     LLQADQYGTGS"
     gene            complement(3977..4822)
                     /locus_tag="AMK26_RS19490"
                     /old_locus_tag="AMK26_19215"
     CDS             complement(3977..4822)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037720.1"
                     /locus_tag="AMK26_RS19490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19215"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073755953.1"
                     /transl_table=11
                     /translation="MSTLRVSRATPEDWSVVGEWAAAEGWNPGLSDGPSFFAQDPGGFF
                     LGRLDGERDPVSAISVVNYSDAYAFLGFYLVRPDRRGLGHGLATWKAALAHAGDRTVGL
                     DGVPAQQANYRRSGFALAHRTARYVGAVSPRTPGAGVVPAAEVGLAAIAAYDSGCYPAE
                     RPRFLERWLGAPGHRALARVVDGRLAGYGVIRPALEEARVGPLFADSPGDAEVLLDALV
                     DGFGAERVAVDVPESNAEAVRMAQARGLVPSFRTARMYTGPVRPFAQERVFGVSTLELG
                     "
     gene            4870..5478
                     /locus_tag="AMK26_RS19495"
                     /old_locus_tag="AMK26_19220"
     CDS             4870..5478
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849389.1"
                     /locus_tag="AMK26_RS19495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19220"
                     /product="DUF6629 family protein"
                     /protein_id="WP_073755954.1"
                     /transl_table=11
                     /translation="MCWSATADLAAGTVITAVGALCVARARGVRELPLAALPLLLGAHQ
                     IVESAVWDAGGGSGPATLAWAVIALPLLPLWLPLGVLLVTPAASRARLTVPAAAGLVTA
                     AALAYCLATRPVTAHIRGRTIGYVLDLPYAPLLVAGYLLATVGALLLAADRGLRILGAV
                     VAAGAALCVALWRTEFVSTWCAFAAVASLLLLARTRRTG"
     gene            complement(6045..6824)
                     /locus_tag="AMK26_RS19505"
                     /old_locus_tag="AMK26_19225"
     CDS             complement(6045..6824)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268099.1"
                     /locus_tag="AMK26_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19225"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_073755956.1"
                     /transl_table=11
                     /translation="MPTRNEIEIRGLYKSFGDNEVLRGIDLDVATGEVVCVIGPSGSGK
                     STLLRCVNLLEEPTRGQVFVGGTEVTDLDVDIDAVRRRIGMVFQQFNLFPHVTVTENLT
                     LPQRRVLGRGKEQAAKVARENLARVGLADKADAYPAQLSGGQQQRVAIARALAMGPEVM
                     LFDEPTSALDPELVGDVLAVMRMLAAEGMTMMVVTHEMSFAREVADRVVFMDDGRIVEE
                     GPAAQVVGDPRHERTRHFLTRILDPAAAEPPGPEDTR"
     gene            complement(6834..7634)
                     /locus_tag="AMK26_RS19510"
                     /old_locus_tag="AMK26_19230"
     CDS             complement(6834..7634)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044507.1"
                     /locus_tag="AMK26_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19230"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_073755957.1"
                     /transl_table=11
                     /translation="MTSRLTRRQRRRISRGVQYAVFVAVVVLIAVLADWDRLQNQFAQA
                     DLAGRLFPDIITTALRNTVVYTLSGFAFGLVLGLVIALMRLSSVAPYRWAASVYIEIFR
                     GLPALLIFIFVGVAVPLAFPGTEIPGGTYGKVALGLGLVAAAYMAETIRAGIQAVPKGQ
                     MEAARSLGFSHARAMVSVILPQAYRIIIPPLTNELVLLFKDSSLVLFLGVTLQERELTK
                     FGRDLASQTANSTPILVAGLCYLLVTIPLSFVVRRLEARAARAK"
     gene            complement(7631..8401)
                     /locus_tag="AMK26_RS19515"
                     /old_locus_tag="AMK26_19235"
     CDS             complement(7631..8401)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044506.1"
                     /locus_tag="AMK26_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19235"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_241838001.1"
                     /transl_table=11
                     /translation="MLLVATGCGNGDEGPGEAAGGVPVVEKGKLTTCTHLPYPPFQFEQ
                     DGEIVGFDVALIDLVAKNLKVEQKILDTPFENFKTGAFLNSGECDLAAAGMTITEERKK
                     NVDFSVPYFDATQALLATKKSGATSLADVKAKKLKLGAQAETTGESYATSQGFDPVAFE
                     SSDAVLNGLRTGQVDAVVIDYPVVQGWLKDKANADAFALGQNIETGEQYGFSVKKGNDK
                     LRAAIDKAIKDAKADGTYNKLYEQWIGPLPKGLS"
     misc_feature    complement(8529..8544)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(8556..8572)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.79"
                     /tool="antismash"
     gene            8841..9992
                     /locus_tag="AMK26_RS19520"
                     /old_locus_tag="AMK26_19240"
     CDS             8841..9992
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013887.4"
                     /locus_tag="AMK26_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19240"
                     /product="hypothetical protein"
                     /protein_id="WP_073755958.1"
                     /sec_met_domain="DHQ_synthase (E-value: 9.7e-19, bitscore:
                     63.2, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYPTTAPTTTPPTTTPPTAISMDRAILAGNLHFPVLVRGGDATWP
                     ELTRIATDLAADAFWLVTDAGLPRGHTARVLSALGPAAPTRVLRAPAPDTAWDETPTPD
                     TVVVALGGSTVIEAAARLAAGTPDRPRLLLVPTTPRAMTDTALSLEHPAAHGLAPTLVW
                     AQLDLLRTLPPDELRTGLAALVRNVLAVSPSFYDTAAALLRPDVTGFDAPLMARVVALN
                     ADIRATLMYYDPSEQGPAMAFSYGRTVADALLSMGAGLSEGDAAALGMLVAARVAVLLG
                     LLDPAAERAHHELMARWGAPRKLPAPLTVDTVAAVLRRGAATGPVPAPYAGPARMVLLD
                     GLGAPHVVRGRMLTEVDDDVLRPALDVIAPHTPVSETDLITID"
     gene            10001..11197
                     /locus_tag="AMK26_RS19525"
                     /old_locus_tag="AMK26_19245"
     CDS             10001..11197
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: salQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359798.1"
                     /locus_tag="AMK26_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19245"
                     /product="sedoheptulose 7-phosphate cyclase"
                     /protein_id="WP_073755959.1"
                     /sec_met_domain="salQ (E-value: 6.6e-178, bitscore: 586.9,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 3.2e-63, bitscore:
                     209.0, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAHHTDPHGLFTHGGPVRSWTVSTAKPVSYRVGFAPGVFNPSNS
                     ALAKAGAVDGGPAPARRLLVVEERVDMLYGDLIRAYCDARGHDEYAIHVLPAHERLKTM
                     DSVFSVVAAMDRFGLDRRREPVVAVGGGVLLDIVGLACSLYRRSTPYVRVPTTLIGLVD
                     AGVGAKTGVNFGTGKNRLGTYHPATETLLDPGFLATLDERHVSNGMAEILKIALIKDAD
                     LFALLETHGARLVADHFQPAGATGDEVLGRAVHGMLEELHDNLWEHKLERVVDYGHSFS
                     PTLEMRALPALLHGEAVALDMALTTVIACRRGLMSTDQRDRVLNVMRTLRLPVTHPLCE
                     PGVLKEALADTVRHRDGKQRLPLPVGIGGSVFVNDLTTGELARAAGDLAALGEVTSHA"
     gene            11190..11894
                     /locus_tag="AMK26_RS19530"
                     /old_locus_tag="AMK26_19250"
     CDS             11190..11894
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019498.4"
                     /locus_tag="AMK26_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19250"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_073755960.1"
                     /transl_table=11
                     /translation="MREAVVVADVHAPADVHGVHAAEGHSRWTCLARRTGLHGGWEAVE
                     WAWLPPGGVSGEHLHSRTEELYFLLSGRGEITLDGRPLPVRAGDTVLTGLGTRHALRNT
                     GRRPLAWLVVELTTTDTTKEQQMDRHRSAVIRDLRRHGPLDASTVLTGPLRTVRLTRLP
                     AGGSTALDAHGEEHTVFITGGSGTARATGRHVSVTRGTALTLPLGTSVWLSAGSEGLEY
                     FHAALAVPEGPQ"
     gene            11891..12388
                     /locus_tag="AMK26_RS37350"
                     /old_locus_tag="AMK26_19255"
     CDS             11891..12388
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS37350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_19255"
                     /product="hypothetical protein"
                     /protein_id="WP_073755961.1"
                     /transl_table=11
                     /translation="MIIHSGDRASVLLGPGGERTTIRCLARRGMLHSECEAFDEVRLDP
                     GTRLDLSGRDGTEAAWYVLSGSVTPDVTPDVTADAPPGAPPGAPPGAPPEDAPGAPPDG
                     PVRDAPAPLTARALVLGRHGDRVRLTAGPDGAALLCLTLTPPAVTRTLPPRTPSIPEEH
                     PS"
     gene            12385..12930
                     /locus_tag="AMK26_RS19540"
                     /old_locus_tag="AMK26_19260"
     CDS             12385..12930
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359803.1"
                     /locus_tag="AMK26_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19260"
                     /product="VOC family protein"
                     /protein_id="WP_073755962.1"
                     /transl_table=11
                     /translation="MTAHPQLVPGVTAVHHVAYTVPDLDEAVGFFTGVLGAELAYRTGP
                     IADPDGQWMARQLGVHPHAVAHIAMLRLGPVTNVELFAYEAPGQRRAYPRNSDWGGHHL
                     ALWTDDFDASLRRLTAHDGVRPLGEPQTVGDGPIAGTRFLYLRTPIGLHIELVQAPARL
                     PYHHETPVRLFDPAGGTS"
     gene            12927..14465
                     /locus_tag="AMK26_RS19545"
                     /old_locus_tag="AMK26_19265"
     CDS             12927..14465
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359805.1"
                     /locus_tag="AMK26_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19265"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_073755963.1"
                     /transl_table=11
                     /translation="MNGTIWGRGAPPVVIQEQDTYDADVAVIGSGAGGSTLAWALASTG
                     ARVLVVERGGFLPHEEANWSPDAVFGEGRYHNAGTWHTADGRPFTPANHYYVGGTTKVY
                     GAALPRLRVSDFDATEQLEGTSPGWPFSYADLEPYYAEAERLYRVHGQDGADPTAPPRS
                     EPYPHPPVPHEPVIGELAAKLTDQGLHPFPVELGIDLAARGACLRCGTCDAFPCRVDAK
                     SDAETRALRPALRTGTVRLLTRTRAERLLTDPAGRRVTAVDAERGGRTVRIWAGTVVVS
                     CGAINSAALLLRSGGAAHPDGLANGSGLVGRNLMVHNNSVLMAVDPRRRNPVTFQKTLA
                     VNDFYHPLGNLQLMGKVHEAALAASHPHVPRRILGAVAARSVDWWVMSEDLPDPDNRVL
                     PGPDGGVILRRRPTNTRAHRGLVRGAARMMRRAGYPLVLRRRMGVEATGHQCGTTVAGL
                     DETRSVLDPHCRSHQVRNLFVVDGGFFPSSAAVNPTLTIAAQALRTAREGGVLP"
     gene            14483..15604
                     /locus_tag="AMK26_RS19550"
                     /old_locus_tag="AMK26_19270"
     CDS             14483..15604
                     /NRPS_PKS="Domain: PKS_ER (20-283). E-value: 5.6e-12.
                     Score: 37.3. Matches aSDomain:
                     nrpspksdomains_AMK26_RS19550_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359806.1"
                     /locus_tag="AMK26_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19270"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_073755964.1"
                     /sec_met_domain="ADH_N (E-value: 1.8e-25, bitscore: 84.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.7e-24, bitscore:
                     80.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSATAAVVRAPGHAFTLEEIRVDAPRPDEVLVRVRAVGICHTDL
                     SVRAGHTPFPLPAVLGHEGTGTVEAVGAAVTSVAPGDTVVMSFASCGACPECLTGHPVR
                     CAHWPALNLFGGSRLDGSPTLRGTGRHADAPLHGHFFGQSSFATLALASVRDVVPVPGD
                     LPPQVVAPFGCGVQTGAGAVLNVLRPEPGHTLAVYGTGSVGLAAVMAARLTAATRVVAV
                     DPDAGRRALALRLGATDAVDPGDADPLEVVRDLTGGRGADRALETSGLPRVLRQAVDGL
                     AVGGVCGVVGAPPAGTDVCLDVPRMLDRGPRIVGVNQGGVVPRVSIPALLDLYRAGRLP
                     VDAIVETFPFAAIEEAAAAATSGKVVKPVLTMP"
     aSDomain        14543..15331
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS19550_PKS_ER.1"
                     /evalue="5.60E-12"
                     /label="AMK26_RS19550_PKS_ER.1"
                     /locus_tag="AMK26_RS19550"
                     /protein_end="283"
                     /protein_start="20"
                     /score="37.3"
                     /tool="antismash"
                     /translation="IRVDAPRPDEVLVRVRAVGICHTDLSVRAGHTPFPLPAVLGHEGT
                     GTVEAVGAAVTSVAPGDTVVMSFASCGACPECLTGHPVRCAHWPALNLFGGSRLDGSPT
                     LRGTGRHADAPLHGHFFGQSSFATLALASVRDVVPVPGDLPPQVVAPFGCGVQTGAGAV
                     LNVLRPEPGHTLAVYGTGSVGLAAVMAARLTAATRVVAVDPDAGRRALALRLGATDAVD
                     PGDADPLEVVRDLTGGRGADRALETSGLPRVLRQAVDGLAV"
     CDS_motif       15077..15115
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK26_RS19550_0001"
                     /evalue="2.10E-02"
                     /label="PKSI-ER_m5"
                     /locus_tag="AMK26_RS19550"
                     /protein_end="211"
                     /protein_start="198"
                     /score="7.7"
                     /tool="antismash"
                     /translation="GTGSVGLAAVMAA"
     misc_feature    15605..15621
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.01"
                     /tool="antismash"
     gene            15653..16342
                     /locus_tag="AMK26_RS19555"
                     /old_locus_tag="AMK26_19275"
     CDS             15653..16342
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359808.1"
                     /locus_tag="AMK26_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19275"
                     /product="response regulator transcription factor"
                     /protein_id="WP_241837970.1"
                     /transl_table=11
                     /translation="MSEEGETPDAAERPVLRTLIVEDHPLFRNGLKSALENLGEVLVVG
                     EAETVAEVPDAVGRCRPDVVVMDLSLPDGSGIEAIRRLAELHPGLPVLTLTMSDDDGDL
                     LAALQAGARGYVVKGASADEVLHAVRTVAAGGAVFGAGVAARLTGLVSGSRRRDAEQLF
                     PALTAREVEVLELIARGFDNRRIARELVLSEKTVRNHITHIFEKLHVATRAEAVARARD
                     AGLGEDA"
     gene            16557..18683
                     /locus_tag="AMK26_RS19560"
                     /old_locus_tag="AMK26_19280"
     CDS             16557..18683
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="AMK26_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19280"
                     /product="ATP-binding protein"
                     /protein_id="WP_143608562.1"
                     /transl_table=11
                     /translation="MPRPQTTRGTPGAGPAALPAYVVCVVAMLSGFLWVTLVLVHPVHP
                     VLDTITLHYAAIGALLAMGLALSGMALVARGSGLALGWLLLSTGGVFAGGAALSLTAGL
                     AGVPPAVATVLILVDVTGYALFGTVVYTLPLWLPDGRFPRGWARAYAIALTVWSFAQQL
                     YEFIQLDTWYMDNPLAGGGWAGLGQWAAPVMVPAIEWVPPFAAGAALLILVVRWYRTPA
                     AGRGNYFLALPYLVWLAVMYFGAYADTPRTVVYAVQYLGAAVWPAALAFIDLRERAWHL
                     DRAARRILTALVLTFVLFLVYGAGGLLVWNAGLRDLDGSTLLPFAVALLIGALLRPTAR
                     WASRVVDRYYYGARAQPYQVVRDLADRLSKAPDPGEAPRLLCATVVHTLGLSAAALTVD
                     THHGPRELVALGHLGPAGENFPLCYQGEEIGRLTVPPRPGELALDPQDREAVQVLADHA
                     APAIASLRLYEDLQSSREQIIVAREEERRRLRHDLHDGLGPALSGLRLQVDAVRCTAQP
                     DVAGPLLTVSEGIGRAIRELRHITDGLAPAALDGADLSRALRQLGEHLSSRTLSISVTV
                     RPDPLPRLSAALEVAVYRITAEALNNAVRHSHADHAHAMVTVADDTVTVQVHDNGDGFS
                     DHQQHAGVGLRSMAERSDELGGRFTLTSSADGTVVRAVFPSRPASAVATRPIASGTTTG
                     PQPHAPETRDRPDS"
     gene            18743..18910
                     /locus_tag="AMK26_RS37030"
     CDS             18743..18910
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS37030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158071134.1"
                     /transl_table=11
                     /translation="MARTSRPRSSKAKAAGAATAAAAALISIPWAVRRMRRQEGVTKAA
                     GCIPICKKGG"
     gene            complement(18943..19443)
                     /locus_tag="AMK26_RS19565"
                     /old_locus_tag="AMK26_19285"
     CDS             complement(18943..19443)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548583.1"
                     /locus_tag="AMK26_RS19565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19285"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073755967.1"
                     /transl_table=11
                     /translation="MPMMRRARVSDHRTLVECVHRWWGDSRTPAEARELSLLLPRLFLQ
                     CFAGTSLVAEDSTGVKAFLVGLYSGDNEEDAYIHFVGVDPALRGRGLARGLYTAFFDRA
                     AEAGRREVRAVTSPGNTGSIAFHRALGFSLVASDDEVEGVPVHRDYDGPGQDRVCFRRK
                     IEV"
     gene            complement(19445..20416)
                     /locus_tag="AMK26_RS19570"
                     /old_locus_tag="AMK26_19290"
     CDS             complement(19445..20416)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470423.1"
                     /locus_tag="AMK26_RS19570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19290"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_073755968.1"
                     /transl_table=11
                     /translation="MDGEPGGSDPSVRQLRLLLVLAEELHFGRAARRLYISQPAFSRQI
                     RRLEDHLGVVLLERSTRRVQLTAAGEALLPRVRAMVEAADQLREAVRAEAGAPAGRVVL
                     GCYITALPVITALAERVRARHPGVEVVLREVDFVEQTAALLDGRVDAVVAYAPMPPGIQ
                     TLPLATERQVVCLWEKHPLAGRTSVSVAELAHLPVIGVSPLVARVWRDFWAADPRPDGA
                     PVTYTGHATTTFEGGMSAVIQGHGIRFVSAGCRELFPRPGIRYVDVSDTPVYTAVLAWS
                     SARRDTPEVAALRLAAGGMVGRGRTDPNPRWWHTEHTESKGD"
     misc_feature    20443..20458
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.33"
                     /tool="antismash"
     gene            20527..20913
                     /locus_tag="AMK26_RS19575"
                     /old_locus_tag="AMK26_19295"
     CDS             20527..20913
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025607.4"
                     /locus_tag="AMK26_RS19575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_19295"
                     /product="DUF4345 domain-containing protein"
                     /protein_id="WP_073755969.1"
                     /transl_table=11
                     /translation="MSARRGFQSVLVLLAVFVLVTGALEIIVGPSLLPGDPEVSTTVDS
                     NYRFFAGIWCSLGIILAVAARRPDSHAPALRAVFGAVFLGGVARGISYLDVGAPHAMHT
                     AFIGVELLLPPLMLFWYTRIHPTL"
     misc_feature    complement(21068..21079)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.02"
                     /tool="antismash"
ORIGIN
        1 gtgacaccgg ggccagtggg cccgcccggg ctgccgcccg ccgccccgcc gcccatgggc
       61 gcgccgagga gcgcgccgtc cggctcgccc tccacggctc tgccaccggc cagtcgcagc
      121 ccggtcggcc cggacggctc ggccggtccg cccggctggg tggccccggg gccgcccggg
      181 cctccggtga caccggggcc agtgggcccg cccgggctgc cgcccgccgc cccgccgccc
      241 atgggcgcgc cgaggagcgc gccgtccggc tcgccctcca cggctctgcc cccggccagt
      301 cgcagcccgg tcggcccgga cggctcggcc ggcccgcccg gctgggtggc gtcttgcgag
      361 tggttcctca cgggtgttcc gccctcctcg tcggcctgcg ggaggcggtt cgggtacccg
      421 ggcctctctc ttttatggct cggttctccg ccgtggcccc ggaactcggt tcactcgccg
      481 gggtcccggt ggtcgcggcg ggacgccctg gtcaggacgg cgccggtggt gacgagcagg
      541 acggcgccgg cgcccaggag ccagagcttc gggcgggcgc ccgtgtccgc catctcggcg
      601 ccctcggccc gctcggcgcg cggctcgccg cgcggggcgg gggagggctc ggcgggggag
      661 ggctcggagg ggggccgggc gtccgtgacg gcttccgagg cggcgggctc cggttccggg
      721 ccggggacag cgggctccgg ttccggttcg ggctccgcgt ccggctcgcg cttcggccca
      781 ggctccggct tcggttccgg tccgggcgcg cccggtggtg acagggccgg tgagggggag
      841 tgcgcgggcg ccgccgccgg gtcgtcgtcg cacgacggtt ccgccgcgaa aggggcgttg
      901 cggatgccgc ccgcgagggg gcccgccttc agcgcgcgga ccacgacgtc gccctcgatg
      961 tcggccgggc tgccgtccgt cagttccgcg cgcggtgcgt agacggatcc ggtgagggtg
     1021 tcgcccgccg tgagggcgat gtcggtggcg tcggcgaacg tccacaggat gtacggggcc
     1081 ccctcgcccc cgacgcccgc catcgtcggc gtacgccagg acagctcgcc gccctcggcc
     1141 gtcgtgtcga ccacgatcac gagcgggcgc gcggccgtcg gccggttctc gaacgccagc
     1201 acccggatgc cggcgagccg cgcgccggtc agtcgcagca cgttcgtacg gtcgtcggcc
     1261 agccggacgc gcacggtggc gccgcccgcg tcgcgcggcg tcaccgtggc ccggcaccgg
     1321 gccagtgcgt cggcgcgctg ccggtggccg gcgaagaggg tgccgaagtc gatgaggccc
     1381 cgcgccggcc ccaccgacgg gggcggctgc gcggtggtca gctcgacgcg cggcgtcgtg
     1441 ccgtacccgg ccccggccgc gaccagccgg gtcctgaccg gcgtgccgtt catgccggtg
     1501 gtccgcgcgc cgccgccgag gtcgcccacc ttgacgtagc ggtcgccggc cacccgcagc
     1561 accgcgtcca ccgcgctgcc ggggaagtcg accgcgccgt cgaccaggag agcggtgggc
     1621 cgcgcgtccc cgggagccac gaagccgccc gcgccgcgcg gcgcgacggt gtaccgcgac
     1681 ccgagggcga ggtcgccgcc cacggcgacg gcgctcccgg actccgtacc gcccagccgc
     1741 gcgtcccggc gcgtgacgac accgaagccg tggttcccgg ccatcgggtt gccgatcacg
     1801 gtggaggtct cgtgtgcccc agccgccggt gttccggggc tcaccgcgca cagcccgcac
     1861 accaccgccg gaatcacggc cgccagtcca gtcgttcgca tagcggagaa aataggatca
     1921 tcggacccat ggtggcgggg acgcgcccac ccggccgggc gacgtttcac ccggtcggcg
     1981 gtgggggagc ggttgctgcg acggcaaggg cgccgcagcc ggggggtggg gatcgtgcgt
     2041 gacaagaagc tgttccggcg ggcctggagg gccgagccac ccgtctccga cagcgaacgc
     2101 gagctcttcg gcggagccct gcgctacgac ttcggctggg tcaagcacga gtacgccgtg
     2161 ctcgacctca agcccctggc cgccgtccgc gccctgcccc gcctcatcgg cagcaccctc
     2221 cggctctcct gggagtccga ccggcgcgcc ctgctcaccg tcggcctcac cgagatcggc
     2281 cagggcatcg cccaggccgt gggactgctc ctgacgaacc aggtcctcca ggccctcttc
     2341 gccgccggca ccaccaccga acgcctccgc gccgccctgc ccgcgctgat cgccgccggc
     2401 gtcctcgccg tggtcaacgc ggtcctcgcc tccctctcca cggcaggcac cggccgcctg
     2461 gagcccaaag tggaacggct cgccaccgag aagtacctcc accgcgccgc cggagtggag
     2521 ctcgaagcca tcgaggacgg ggcgttccgc aagctcctgg actcggccca gttcggcgcc
     2581 ctggccgccc ggaacatgat cggcgcctgt gtgggcgccc tcaacggcgt gttcaccatc
     2641 gtcgccgccg ccggtgtcct caccgtgctc cacccggcgc tcctgccact gctcgtcctg
     2701 atcgccctgc cgcgcggctg gggcgccatg catgtggcac agcgccgcta cgcctcccgg
     2761 atgaactgga tcgagcacga gcgagcggcc cgcctcgtca acaacctcat caccagccgt
     2821 gagtcggccc aggagatccg cgtccaccag gtcggccgct acctcctcga caagttccac
     2881 gacatggccg agacctccga ggccgagcag acccgcctcg ccgacggacg cgccgtcacc
     2941 gagctgctcg ccgccgcgtt ctccggcgtg gccgccctcc tcacgtacgc cgccctcggc
     3001 gccctgctgg tcaccggccg catggacatc gccatggccg gcacagccgc cctcgcggta
     3061 cgcaccggct cggccagcct cagcgcgctg atcacccaca tcaacaccct gcacgaggag
     3121 tccctgtacg tccgcgacct cgaccgtttc actgccgccg ccgaatcgcg ggccatcccg
     3181 tccggcggca cccccgtccc ggacttcccc gagaagatca ccctggagaa cgtcaccttc
     3241 cgctaccccg atcgcgacga acccgccctg cgcggcgtgt ccctgaccat caccgccggc
     3301 tccgtcgtcg ccctcgtcgg cgccaacgga tcgggcaagt cgaccctcgt caagatcctc
     3361 gccggcctcc acaggccggg cgaggggtgc gtcctgtggg gcgacaccga cctcgccgac
     3421 gccgaccggc tcgacgtctt ccgccatgtc gccgtcctcg accaggactt ccagcgctgg
     3481 cccttcaccc tccacaccaa catccgcatc gggcagcccc acgccgcccc gcacgccggc
     3541 cgggtcgagc gcgccgccgc ctactccggc gccgacaggc tcggcgccac cctgccacgc
     3601 ggctacgaca ccctgctcgc ccgccagttc cggcacggct ccgagctctc cggcggccag
     3661 tggcagaccg tcggccaggc ccgcctccgc taccgggagg cgggcctcgt catcgccgac
     3721 gagccgacct ccgccctgga ccccgaggcg gagatcgagt cgttccaacg catccgcgcc
     3781 ctcaccggcg agggcaggac cgtcgtgctc gtcagccacc gcatggccgg catccagtcc
     3841 gccgacgtca tccacgtcct ccacgagggc aggctcgtcg agtcgggctc gcaccgggag
     3901 ctgatggacc ggccgggctc ccgctaccgg cgcatgtacc tcctccaggc cgaccagtac
     3961 gggaccggct cctgagtcac cccagctcca gggtgctgac gccgaagacc cgctcctggg
     4021 cgaacggcct caccggcccc gtatacatgc gtgccgtacg gaacgacggc accaggcccc
     4081 gcgcctgggc catccgcacc gcctccgcgt tcgactccgg tacgtccacg gcgacccgct
     4141 ccgccccgaa accgtccacg agcgcgtcca gcagcacctc cgcgtcaccc ggcgagtcgg
     4201 cgaacagcgg accgacccgg gcctcctcca gcgccggccg gatcaccccg taccccgcca
     4261 ggcggccgtc cacgacccgc gccagcgccc ggtggccggg cgcgcccagc caccgctcca
     4321 ggaaccgggg ccgctccgcc gggtagcagc cgctgtcgta cgcggcgatc gcggcgagcc
     4381 ccacctcggc ggccggcacc acacccgccc ccggcgtacg cggcgacacc gcccccacat
     4441 agcgcgccgt gcggtgcgcc agggcgaacc ccgagcggcg gtagttggcc tgctgtgcgg
     4501 gcaccccgtc gaggccgacg gtgcggtccc cggcatgggc gagcgccgcc ttccaggtgg
     4561 ccagcccgtg cccgaggccg cgccggtcgg ggcgtaccag atagaagccg aggaaggcgt
     4621 acgcgtcgct gtagttgacg accgagatgg ccgacaccgg gtcccgctcg ccgtcgagcc
     4681 tgccgaggaa gaacccgccg ggatcctgcg cgaagaagct cggcccgtcc gaaaggccgg
     4741 ggttccagcc ctccgccgcg gcccattccc cgaccaccga ccagtcctcc ggcgtcgccc
     4801 gcgacacccg cagcgttgac aagggatctc ctcccggccg tcgtacggtt cccctcgtac
     4861 gctacccaca tgtgctggag cgcgacggcc gacctcgcgg ccggcaccgt catcaccgcc
     4921 gtcggcgccc tgtgcgtggc ccgcgcccga ggcgtacgcg aactgccgct cgccgccctg
     4981 cccttgctgc tcggcgccca ccagatcgtc gagtcggccg tctgggacgc cggcggcggc
     5041 agcggccccg ccaccctggc ctgggccgtc atcgcgctgc cgctgctgcc cctctggctg
     5101 ccgctcggcg tcctgctcgt cacgcccgcc gcgagccgcg cccgcctcac cgtcccggcc
     5161 gccgccgggc tcgtgacggc cgccgctctc gcgtactgcc tcgccacccg gccggtgacg
     5221 gcccacatcc ggggccgcac catcggctac gtcctcgacc tcccgtacgc cccgctcctc
     5281 gtcgccggct acctcctggc caccgtcggc gccctgctcc tcgcggccga ccggggcctg
     5341 agaatcctcg gcgcggtcgt cgcggccggg gcggcgctgt gcgtcgcgct gtggcgcacc
     5401 gagttcgtct ccacctggtg cgccttcgcc gcggtggcgt ccctgctcct gctcgccagg
     5461 acccggcgta caggctgagg gctcagtgac gtccctccct cagggcgaag gtctggggac
     5521 cgagttgccg ggggcgcggc ctcatgctgc acttggactc atcggcgcgg gcgacctcgg
     5581 tgtcccccgg cccatcgcat ggcatgcttt tcgagcgctg cgctctgcct cggagtgccg
     5641 gggcacgagc gttcccggcg atacccagtt tccccggaga cgcacatgcg aagcgaatcg
     5701 acgtgtacct ggggggtatt gcgcaagagg tcggctgtgc tggttgccgg gctgttgatc
     5761 ggcgcactca gcgatctcag cagcatgaac tctgctgcgg cggccggccc ttacggcccg
     5821 gatacatgtg tcaagggata tgtgtggcgc gaggcgacag ccgccgatca tacctgcgtc
     5881 gctccgagcg tccgtgagta tcaccgtcgg cagaccaatg ctgcggtttc gtgggccgtg
     5941 cctatgcctc tcgtcgaggc ggagggctgg ttccgcggct agagggtgac cagcgggtgg
     6001 ccggggcctg ttgcgcgaca ccgccgttgc ggaacggagc gcacctagcg ggtgtcctcc
     6061 ggtcccggag gttcggcggc ggccgggtcg aggatgcggg tcaggaagtg gcgggtacgt
     6121 tcgtgccgtg ggtcgcccac gacctgggcg gccgggccct cctcgacgat ccggccgtcg
     6181 tccatgaaca ccacccggtc ggcgacctcc cgggcgaagc tcatctcgtg cgtgacgacc
     6241 atcatcgtca tgccctccgc cgccagcatc cgcatcacgg ccagcacatc gccgaccagc
     6301 tcggggtcga gcgccgacgt cggctcgtcg aacagcatca cctccgggcc catcgccagc
     6361 gcccgcgcga tcgccacccg ctgctgctgc ccgcccgaca actgcgccgg ataggcgtcc
     6421 gccttgtccg ccagcccgac gcgcgccagg ttctcccggg cgaccttcgc cgcctgctcc
     6481 ttgccgcgcc ccagcacccg ccgctgcggc agcgtgaggt tctcggtcac ggtcacgtgc
     6541 gggaagaggt tgaactgctg gaacaccatg ccgatccggc ggcgtacggc gtcgatgtcg
     6601 acgtccaggt ccgtgacctc cgtaccgccc acgaagacct gccccctggt cggctcctcc
     6661 agcaggttca cgcagcgcag cagtgtcgac ttgccggagc cggacggccc gatgacgcac
     6721 accacctcgc cggtggcgac gtccaggtcg atgccgcgca gcacctcgtt gtcgccgaag
     6781 gacttgtaca gcccccggat ctcgatctcg ttccgtgtcg gcatcggtat ccctcacttg
     6841 gccctggcgg cacgggcctc gaggcggcgc accacgaagc tcagcggaat cgtcaccagc
     6901 aggtagcaca ggccggcgac gaggatgggt gtggagttgg cggtctggct ggccaggtcc
     6961 cggccgaact tcgtcagctc ccgttcctga agtgtcaccc cgaggaacag caccagcgag
     7021 gagtccttga acagcagcac cagttcattg gtgagcggcg ggatgatgat ccggtacgcc
     7081 tgcgggagga tcaccgacac catcgcgcgg gcgtgcgaga agcccagcga acgcgccgcc
     7141 tccatctggc ccttgggcac cgcctggatg cccgcccgga tcgtttccgc catgtacgcc
     7201 gcggccacca gcccgaggcc gagggcgacc ttgccgtacg tcccgccggg gatctccgta
     7261 cccgggaacg cgagcggtac ggcgacgccc acgaagatga agatcagcag ggcgggcagg
     7321 ccgcggaaga tctcgatgta gacgctcgcg gcccaccggt agggcgccac cgacgacagc
     7381 cgcatcaggg cgatgaccag gcccaggacg aggccgaagg cgaacccgga gagggtgtac
     7441 accaccgtgt tgcgcagcgc ggtggtgatg atgtccggga agagccgccc cgccaggtcc
     7501 gcctgcgcga actggttctg cagccggtcc cagtcggcca ggacggcgat caggacgacg
     7561 acggcgacga agaccgcgta ctgaacgccc cgcgagatcc gccgccgctg ccgcctcgtc
     7621 agccgtgagg tcacgacagg cccttgggca gcgggccgat ccactgttcg tagagcttgt
     7681 tgtacgtgcc gtccgccttg gcgtccttga tcgccttgtc gatcgcggcg cggagcttgt
     7741 cgttgccctt cttcaccgag aagccgtact gctcaccggt ctcgatgttc tgccctagcg
     7801 cgaaggcgtc ggcgttcgcc ttgtccttca accagccctg cacgaccggg tagtcgatga
     7861 cgacggcgtc gacctggccg gtgcgcagcc cgttgagcac ggcgtcggag ctctcgaacg
     7921 ccaccgggtc gaagccctgg gacgtggcgt agctctcccc ggtggtctcg gcctgggcgc
     7981 ccagcttcag cttcttcgcc ttgacgtccg cgaggctggt ggcgccgctc ttcttggtcg
     8041 ccagcagggc ctgggtggcg tcgaagtagg ggacggagaa gtcgacgttc ttcttgcgct
     8101 cctcggtgat ggtcatcccg gcggcggcca ggtcgcactc gccggagttg aggaacgcgc
     8161 cggtcttgaa gttctcgaac ggtgtgtcga ggatcttctg ttcgaccttc aggttcttgg
     8221 cgaccaggtc gatcagcgcc acgtcgaagc cgacgatctc gccgtcctgc tcgaactgga
     8281 agggcgggta cggcagatgg gtgcaggtcg tcagcttgcc cttctccacc acgggcaccc
     8341 cgcccgccgc ctcaccggga ccctcgtcgc cgttcccgca cccggtggcg acgagcagca
     8401 gcccggtcgc cgcggcacag gcgatgaaga cggtacgggg ggtgcggtgg gcgcgtcgct
     8461 tggcgccggc agtcctcgtc acggttgacc tccatgggcg cgtgggcggc ctcggatgac
     8521 gccggggggt gacgccgggg tgacgcagcc gccgggcgtg atcgtatgac acggagcgcg
     8581 ccccgtcgcg gagatcgccg ccccggatcc cggcccgggt ccgggcccca tgtcccaggc
     8641 ccccggacac ggcccggtcc atgtcccggt cggcgtcccg ggccggtgcg cgagggggcc
     8701 gggtgcacgt cccggtggga agcggggcag gtcaggggcc gcgtgggggc cggggcctca
     8761 ggtggacggg acagcgggcg cccgacggtg aaggggcgac attccgagac gcaccagtga
     8821 acgagtgaac gagctctctc atgtacccca ccaccgcacc gaccaccact ccaccgacca
     8881 ccactccgcc gaccgccatc tccatggacc gcgccatcct cgccggcaac ctccacttcc
     8941 ccgtcctcgt ccggggcggc gacgccacct ggccggagct gacgcggatc gccaccgacc
     9001 tggcggcgga cgcgttctgg ctggtcaccg acgccggact gccccgcggc cacaccgccc
     9061 gggtgctgtc cgcgctcggc ccggccgccc cgacgcgcgt ccttcgggcc cccgccccgg
     9121 acacggcctg ggacgagacc cccacgccgg acacggtggt cgtcgccctc ggcggcagca
     9181 ccgtcatcga ggccgccgcc cggctggccg ccggcacccc ggaccggccg cgcctgctcc
     9241 tcgtgcccac cacgccgcgg gccatgaccg acacggcact gagcctggag cacccggccg
     9301 cccacggcct ggcgcccacc ctggtctggg cccagctcga cctgctgcgc accctgccgc
     9361 cggacgaact gcgcaccggg ctcgcggccc tcgtcaggaa cgtcctggcg gtcagcccgt
     9421 ccttctacga cacggccgcc gccctgctgc ggcccgacgt gaccggcttc gacgcccccc
     9481 tcatggcacg cgtcgtcgcc ctgaacgccg acatccgcgc cacgctcatg tactacgacc
     9541 cgagcgaaca aggcccggcc atggcgttca gttacggccg caccgtcgcg gacgccctgc
     9601 tgtccatggg cgccgggctg tccgagggcg acgcagccgc gctcgggatg ctcgtcgccg
     9661 cacgggtcgc cgtcctgctc gggctgctcg acccggccgc cgagcgcgcc caccacgagc
     9721 tgatggcccg ctggggagca ccgcgcaagc tgcccgcccc gctcacggtg gacaccgtcg
     9781 cggcggtcct ccggcgtggc gcggccaccg gcccggtacc ggccccgtac gccggacccg
     9841 cccggatggt gctgctcgac gggctgggcg ccccgcacgt cgtacgcggc cggatgctca
     9901 ccgaagtcga cgacgacgta ctgcgcccgg cactcgacgt gatcgccccc cacacccccg
     9961 tatccgagac cgacctgatc accatcgact gaggagaacc atgttcgccc accacaccga
    10021 cccgcacgga ctgttcaccc acggcggccc ggtccgcagc tggaccgtca gcaccgccaa
    10081 accggtcagc taccgcgtcg gcttcgcgcc cggcgtcttc aacccgtcca acagcgccct
    10141 cgccaaggcc ggagccgtcg acggcggccc ggccccggcc cggcggctcc tcgtcgtcga
    10201 ggaacgcgtc gacatgctgt acggcgacct gatccgcgcc tactgcgacg cgcgcggcca
    10261 cgacgagtac gcgatccacg tgctgcccgc ccacgagcgg ctcaagacca tggactccgt
    10321 cttctccgtg gtcgccgcga tggaccggtt cggcctggac cgccgccggg agccggtcgt
    10381 cgcggtcggc ggcggcgtgc tgctcgacat cgtcggcctg gcgtgcagcc tgtaccggcg
    10441 cagcaccccc tacgtccgcg tacccaccac cctcatcggg ctggtcgacg ccggcgtcgg
    10501 cgccaagacc ggcgtcaact tcggcaccgg caagaaccgg ctcggcacct accaccccgc
    10561 caccgagacc ctgctcgacc ccggcttcct cgccaccctg gacgagcggc acgtcagcaa
    10621 cggcatggcg gaaatcctga agatcgccct gatcaaggac gccgacctct tcgcactgct
    10681 ggagacccat ggcgcccggc tcgtcgccga ccacttccag ccggccgggg cgacgggcga
    10741 cgaggtcctg ggcagagccg tgcacggcat gctcgaagaa ctccacgaca acctgtggga
    10801 acacaagctg gaacgcgtcg tggactacgg gcactccttc agccccacgc tggagatgcg
    10861 ggccctgccc gccctgctgc acggcgaggc cgtcgccctc gacatggcgc tcaccaccgt
    10921 catcgcctgc cggcggggcc tgatgagcac ggatcagcgc gaccgcgtcc tgaacgtgat
    10981 gcgcaccctc aggctgcccg tcacgcaccc cctgtgcgaa ccgggcgtcc tcaaggaggc
    11041 gctcgccgac accgtccgcc accgcgacgg caagcagcgc ctgccgctgc cggtcggcat
    11101 cggcggctcc gtgttcgtca acgacctcac caccggcgaa ctggcccgcg cggccggtga
    11161 cctggccgcc ctgggggagg tgacctccca tgcgtgaggc agtcgtcgtc gccgatgtgc
    11221 acgcccccgc cgacgtccac ggcgtacacg ccgccgaagg tcactcccgc tggacgtgcc
    11281 tcgcccgccg caccgggctc cacggcggct gggaggccgt cgaatgggcc tggctgccgc
    11341 cgggcggggt gagcggggag cacctgcact cccgcaccga ggagctgtac ttcctgctct
    11401 ccgggcgcgg cgagatcacc ctcgacggac gcccgctccc cgtcagggcg ggcgacaccg
    11461 tcctgacggg cctcggcacc cgccacgcgc tgcgcaacac cgggcgccgg cccctggcct
    11521 ggctcgtcgt cgaactcacc accacggaca ccacgaagga gcagcagatg gaccgtcacc
    11581 gcagtgccgt catccgtgac ctgcgccgcc acggcccgct ggacgcctcc accgtcctca
    11641 ccggccccct gcgcacggtc cgcctcaccc gactgccggc cggcggcagc accgcgctcg
    11701 acgcccacgg cgaggagcac accgtgttca tcaccggagg gtcgggcacc gcccgcgcca
    11761 cgggccggca cgtgtccgtg acgcggggca ccgccctcac cctgccgctc ggcacatccg
    11821 tgtggctgag cgcgggctcg gaggggctgg agtacttcca cgccgcgctc gccgtaccgg
    11881 agggacccca gtgatcatcc actccggcga ccgggcctcc gtcctcctcg gccccggcgg
    11941 cgaacggacc accatccgct gcctcgcccg gcgcggcatg ctccacagcg agtgcgaggc
    12001 cttcgacgag gtacgcctcg accccggcac ccgcctggac ctgtccggcc gggacggcac
    12061 cgaagccgcc tggtacgtcc tgtcgggctc ggtcacgccc gatgtcacgc ccgatgtcac
    12121 ggcggacgcc ccgcccggcg ccccgcccgg cgccccgccc ggcgccccgc ccgaggacgc
    12181 gcccggcgcc ccgcccgacg gccccgtccg tgacgccccc gcgccgctca ccgcgcgcgc
    12241 cctcgtcctc ggccggcacg gggaccgcgt ccggctcacc gccggcccgg acggcgccgc
    12301 cctgctgtgc ctcaccctca ccccgcccgc cgtcacccgc accctgccgc cccgtacccc
    12361 cagcatcccc gaggagcacc cgtcatgacc gcacacccgc agctggtgcc cggcgtcacc
    12421 gccgtccacc acgtcgccta cacggtgccc gacctcgacg aggcggtcgg cttcttcacc
    12481 ggcgtcctcg gcgccgaact cgcctaccgg accggcccga tagccgaccc ggacgggcag
    12541 tggatggccc gccagctggg cgtccacccg cacgccgtcg cccacatcgc catgctgcgc
    12601 ctcggcccgg tcaccaacgt cgagctgttc gcgtacgagg cgcccggcca gcgccgggcg
    12661 tacccccgca acagcgactg gggcggccac cacctcgccc tgtggaccga cgacttcgac
    12721 gcctcgctgc gccggctcac cgcgcacgac ggggtccgcc cgctcggcga gccgcagacg
    12781 gtcggcgacg ggccgatcgc cgggacccgc ttcctctacc tccgcacccc catcggcctg
    12841 cacatcgaac tcgtccaggc gcccgcccgg ctgccatacc accacgagac accggtccgt
    12901 ctgttcgacc ccgcgggagg cacctcatga acgggaccat ctgggggcgg ggcgctccgc
    12961 ccgtcgtcat ccaggagcag gacacctacg acgccgacgt cgccgtcatc ggatcgggcg
    13021 ccgggggctc caccctcgcc tgggccctgg cctccaccgg cgcccgcgtc ctggtcgtcg
    13081 aacgcggcgg cttcctcccc cacgaggagg ccaactggtc gcccgacgcg gtcttcggcg
    13141 agggccgcta ccacaatgcg ggcacctggc acaccgccga cggccgcccc ttcacccccg
    13201 ccaaccacta ctacgtgggc ggcaccacca aggtgtacgg cgccgccctg ccccggctcc
    13261 gcgtcagcga cttcgacgcc accgagcagc tcgaagggac ctcgcccggc tggccgttct
    13321 cgtacgccga cctggagccg tactacgccg aggccgaacg cctctaccgc gtccacggcc
    13381 aggacggcgc cgacccgacg gcgccgccgc gctcggagcc gtatccccat ccgcccgtcc
    13441 cgcacgagcc ggtcatcggc gagctggcgg ccaagctgac ggaccagggg ctgcacccct
    13501 tcccggtcga gctgggcatc gacctggccg cacgcggcgc ctgcctccgc tgcggtacgt
    13561 gtgacgcctt cccgtgccgc gtcgacgcca agagcgacgc ggagacccgt gcgctgcggc
    13621 ccgcgctgcg caccgggacg gtccggctgc tgacccgtac cagggccgag cggctgctga
    13681 ccgacccggc cgggcgccgg gtcaccgccg tcgacgccga acggggcggt aggaccgtac
    13741 gcatctgggc gggcaccgtg gtggtgtcct gcggggccat caactccgct gccctgctgc
    13801 tgcgttcggg cggggcggcg cacccggacg ggctggccaa tggcagcggg ctcgtcggcc
    13861 gcaacctgat ggtgcacaac aacagcgtgc tcatggccgt cgacccccgg cgccgcaacc
    13921 ccgtgacgtt ccagaagacc cttgccgtca acgacttcta ccaccccctc ggcaacctcc
    13981 agctgatggg gaaggtccac gaggccgcgc tggccgcctc ccacccgcac gtgccgcgcc
    14041 ggatcctcgg cgccgtggcc gcgcgcagcg tggactggtg ggtgatgtcc gaggacctgc
    14101 ccgacccgga caaccgggtc ctgcccggcc cggacggcgg tgtcatcctg cgccggcggc
    14161 ccaccaacac ccgcgctcac cgcggcctgg tgcgcggcgc ggcccgcatg atgcggcgcg
    14221 ccggctaccc gctggtgctg cgccgccgga tgggcgtgga ggccaccggc catcagtgcg
    14281 gcacgacggt cgccggactc gacgagaccc gctccgtcct cgacccgcac tgccgcagcc
    14341 accaggtccg caacctgttc gtcgtcgacg gcggcttctt cccctcctcc gccgccgtca
    14401 acccgacgct gaccatcgcc gcccaggcac tgcgtaccgc ccgcgaaggc ggcgtgctgc
    14461 cctgacacgt aaggagagcc ccatgccttc cgccaccgcc gcagtggtcc gtgcccccgg
    14521 ccacgccttc accctcgaag agatacgggt cgacgcgccc cgcccggacg aggtcctcgt
    14581 gcgcgtacgc gccgtcggca tctgccacac cgacctcagc gtccgcgccg ggcacacccc
    14641 cttccccctg cccgccgtcc tcggccacga gggcaccggc acggtcgagg ccgtcggcgc
    14701 cgccgtcacc tccgtcgcgc ccggcgacac cgtcgtgatg agcttcgcct cgtgcggggc
    14761 ctgcccggag tgcctgacgg gccacccggt cagatgcgcc cactggccgg cgctgaacct
    14821 gttcggcggc agccgcctgg acggcagccc caccctgcgc ggaacgggcc ggcacgcgga
    14881 cgccccgctg cacggacact tcttcggcca gtcctcgttc gcgacgctcg ccctcgcctc
    14941 cgtacgcgat gtggtgcccg tgcccggaga cctgccgccc caggtcgtcg ccccgttcgg
    15001 ctgcggcgtc cagaccgggg cgggcgccgt gctcaacgtg ctgcgccccg agccgggcca
    15061 caccctcgcc gtgtacggca ccggatcggt gggcctggcc gccgtcatgg ccgcccggct
    15121 caccgccgcc acccgggtcg tcgcggtcga ccccgacgcg gggcggcggg ccctggctct
    15181 ccggctgggc gccaccgacg cggtcgaccc gggcgacgcc gaccccctgg aggtggtgcg
    15241 ggacctgacg ggcgggcgcg gcgcggaccg ggcactggag acgagcggtc tgccgcgcgt
    15301 gctgcgccag gcggtggacg gtctcgccgt cgggggcgtg tgcggggtgg tcggcgcccc
    15361 gcccgccggg acggacgtgt gtctggacgt accgcggatg ctcgaccggg ggccgcggat
    15421 cgtcggcgtg aaccagggcg gtgtcgtgcc gcgcgtgtcc atcccggccc tgctggacct
    15481 gtaccgggcc gggcgcctgc ccgtcgacgc gatcgtggag acgttcccct tcgccgcgat
    15541 cgaggaagcc gcggcggccg cgacgagcgg caaggtcgtc aaaccggtgc tgaccatgcc
    15601 ctaatgcctc aaaaatatgc ctccgtcaca aagatcactt accgtctgca gtgtgagtga
    15661 agaaggtgaa actccggacg cggcggagcg gcccgtgctc cgcacgctca tcgtcgaaga
    15721 ccacccgctg ttccggaacg gcctgaagtc cgcgctggag aacctcggcg aggtactggt
    15781 ggtcggcgag gccgagaccg tcgccgaagt gcccgacgcg gtgggacggt gccgaccgga
    15841 cgtcgtcgtg atggacctgt cccttccgga cggctccggc atcgaggcga tccgccggct
    15901 cgccgagctc catcccgggt tgccggtcct caccctcacc atgtccgacg acgacggcga
    15961 cctgctcgcc gcgctccagg cgggcgcgcg cggctacgtc gtcaagggcg cgagcgcgga
    16021 cgaggtgctg cacgccgtgc gtaccgtcgc ggcaggcggc gccgtgttcg gcgccggagt
    16081 cgccgcccgc ctgacggggc tggtctccgg cagccggcgg cgcgacgccg agcagctctt
    16141 cccggcgctg acggcgcgtg aggtggaggt cctggagctg atcgcccgcg gtttcgacaa
    16201 ccgccggatc gcccgcgagc tggtgctgtc ggagaagacc gtgcgcaacc acatcacgca
    16261 catcttcgaa aagctgcatg tggccacccg cgccgaggcc gtcgcccgcg cccgggacgc
    16321 cggcctcggc gaggacgcct gactccaccg cccctgcccg gggaccgctg cccggaacca
    16381 ggacaccggc ccggggcacc ggcccaggag gcgccggccc ggaaccagtg cgggaccggc
    16441 ccggaaccag gcgggaccgg ggcgggaccg gggatgggac atccacctca tgcggccggg
    16501 acagcgggcc gcccaccctg aacgtgaacg ggagcaccga ccgcgaggag cgtgagatgc
    16561 ctcgaccgca gaccaccagg gggactcccg gagccggtcc tgccgctctc cccgcctatg
    16621 tggtgtgcgt ggtggcgatg ctctccggat tcctgtgggt gacgctcgtc ctcgtccatc
    16681 ccgtccatcc ggtcctggac accatcaccc tccactacgc ggccatcggc gccctgctgg
    16741 ccatggggct cgccctgtcc ggcatggcac tcgtcgcgcg cggctccgga ctcgccctgg
    16801 gctggctgct gctgtccacc ggcggcgtct tcgcgggcgg cgcggccctg tccctgacgg
    16861 cagggctcgc cggagtcccc ccggcggtcg cgaccgtcct gatactcgtc gacgtgacgg
    16921 gctacgccct gttcggaacg gtcgtctaca ccctcccgct gtggctcccc gacggccggt
    16981 tcccccgcgg atgggccagg gcctacgcga tcgccctgac ggtgtggagc ttcgcacagc
    17041 agctgtacga gttcatccag ctcgacacct ggtacatgga caaccccctc gccggtggcg
    17101 gctgggcggg gctcgggcag tgggccgcac ccgtgatggt cccggcgatc gagtgggtgc
    17161 cgccgttcgc cgccggcgcg gccctgctca tcctggtggt ccgctggtac cgcacaccgg
    17221 cggcggggcg cggcaactac ttcctggccc tgccgtacct ggtgtggctc gccgtcatgt
    17281 acttcggcgc ctacgccgac accccgcgga ccgtcgtcta cgcggtgcag tacctgggcg
    17341 cggccgtctg gccggccgcc ctcgccttca tcgacctccg cgaacgggcc tggcacctgg
    17401 accgggcggc ccgccgcatc ctgacggccc tcgtgctgac cttcgtcctg ttcctggtgt
    17461 atggcgccgg cggactgctc gtctggaacg ccgggctccg ggacctcgac ggctcgaccc
    17521 tgctgccctt cgccgtcgcc ctgctgatcg gggcgctgct gcgccccacc gcccgctggg
    17581 cgtcccgtgt cgtcgaccgc tactactacg gcgcccgcgc ccagccgtac caggtcgtcc
    17641 gcgacctcgc cgaccgcctg agcaaggcac ccgacccggg cgaggcgcca cggctgctgt
    17701 gcgccacggt cgtgcacacg ctgggcctga gcgccgccgc cctgaccgtg gacacccacc
    17761 acggcccgcg tgaactggtc gccctcggcc acctcggccc ggcgggcgag aacttcccgc
    17821 tctgctacca gggcgaggag ataggccgcc tgacggtgcc cccgcgcccc ggcgagctcg
    17881 cactggaccc gcaggaccgg gaagccgtcc aggtgctcgc cgaccacgcc gcccccgcga
    17941 tcgcgtcgct gcggctgtac gaggacctcc agagcagccg cgagcagatc atcgtcgccc
    18001 gcgaggagga gcggcgccgc ctgcggcacg atctgcacga cggcctcggc cccgccctgt
    18061 cgggcctccg cctccaggtc gacgcggtac gctgcaccgc ccagcccgat gtcgccggcc
    18121 ccctgctcac cgtctccgag ggcatcggcc gcgccatccg ggagctgcgc cacatcaccg
    18181 acggcctggc gcccgccgcg ctggacggcg ccgacctgtc ccgggcgctg cggcagctcg
    18241 gcgagcacct cagcagccgt acgctgagca tctccgtgac cgtacgcccc gacccgctgc
    18301 cccggctctc cgccgcgctc gaagtggccg tgtaccgcat caccgccgag gcgctcaaca
    18361 acgccgtacg ccactcccac gccgaccacg cccacgccat ggtcaccgtc gccgacgaca
    18421 ccgtcaccgt ccaggtccac gacaacggcg acggcttctc cgaccaccag cagcacgccg
    18481 gggtgggcct gcgttccatg gcggaacgct ccgacgagct cggcggccgt ttcaccctca
    18541 ccagcagcgc cgacgggacg gtcgtccgtg ccgtgttccc ctcccgcccg gcctccgccg
    18601 tcgcgaccag gccgatcgcc tctgggacaa cgacgggacc tcagccccat gcacccgaga
    18661 cccgggaccg cccagactca tgagggacgg ggcaaccccc gctcgagcga caccgacctg
    18721 aagcccaccg aaggagtccc tcatggcccg caccagccga ccccggtcct cgaaggccaa
    18781 ggccgcaggc gccgccaccg ccgcggcggc agccctgatc agcatcccct gggccgtgcg
    18841 acggatgcgc agacaggagg gcgtcaccaa ggcggccggt tgcataccga tctgcaagaa
    18901 gggcggctag cgcgcgggcc cgggaacccc cgggcccgct cgtcacacct cgatcttcct
    18961 gcggaagcag acccggtcct gcccgggccc gtcgtagtcg cggtgcacgg gcaccccctc
    19021 gacctcgtcg tcgctcgcca ccagactgaa gcccagcgcc cggtggaacg cgatcgatcc
    19081 ggtgttcccc ggagatgtca ccgcccgcac ctcccgccgc cccgcctccg cggcacgatc
    19141 gaagaacgcc gtgtacagcc cgcgcgccag gccccgcccc cgcagcgccg gatcgacccc
    19201 cacgaagtgg atgtaggcgt cctcctcgtt gtcgccggaa tacaggccca ccaggaacgc
    19261 cttgaccccc gtactgtcct cggccaccag gctcgtaccc gcgaagcact gcaggaacag
    19321 cctcggcagc agcagggaca gctcacgggc ctccgcgggc gtacgcgaat cgccccacca
    19381 cctgtgcacg cactcgacga gcgtgcgatg gtcggacacg cgcgcccggc gcatcatcgg
    19441 catgtcaatc ccctttggac tcggtgtgct cggtgtgcca ccagcgaggg ttcgggtcgg
    19501 tccttcccct ccccaccatg ccgcccgccg cgagacgcag cgcggcgacc tccggtgtgt
    19561 cgcggcgagc ggatgaccag gcgagcaccg ccgtgtacac gggcgtgtcc gacacgtcga
    19621 cataacggat ccccggccgg ggaaacagct cgcggcagcc ggccgacacg aaacggatgc
    19681 cgtgcccctg gatgacggcc gacatcccgc cctcgaacgt ggtggtcgca tggccggtgt
    19741 acgtgaccgg cgccccgtcc gggcgggggt ccgccgccca gaagtcccgc cacacccggg
    19801 ccaccagggg cgacaccccg atgacgggca ggtgggccag ctccgcgacc gacacggagg
    19861 tccggccggc caggggatgc ttctcccaca ggcacaccac ctgccgttcc gtcgccagcg
    19921 gaagcgtctg gatgccgggc ggcatggggg cgtacgccac gacggcgtcc acccggccgt
    19981 ccagcagtgc ggcggtctgc tcgacgaagt ccacctcccg cagcacgacc tccacgcccg
    20041 ggtgtcgcgc gcgcacccgc tcggcgaggg cggtgatgac cggcagggcg gtgatgtagc
    20101 agccgaggac cacccggccc gccggcgccc cggcctccgc gcgcacggcc tcgcgcagct
    20161 ggtcggcggc ctccaccatg gcccggaccc ggggaagcaa cgcctccccg gcggcggtca
    20221 gctgtacgcg ccgggtggag cgctccagga ggacgacgcc caggtggtcc tccagcctgc
    20281 ggatctggcg gctgaacgcc ggctggctga tgtagaggcg cctggccgcc cggccgaagt
    20341 ggagctcctc ggccagtacg agcagcagcc gcaactgacg cacactcgga tcggacccgc
    20401 ccggctcgcc gtccatgccc tggacggtat caatgagggt gcgaggcgca tcattttccg
    20461 cttcctcaga ggaggcctcc ggccgacgat ggaagccggt catgcacgga cacctgagga
    20521 gcagacatgt cggcacgtcg cggtttccag tcggtattgg tcctgctcgc tgtgttcgtg
    20581 ctggtcaccg gcgcgctgga gatcattgtc gggccctcgc tgctgcccgg cgaccccgag
    20641 gtgagcacca ccgtcgacag caactaccgg ttcttcgccg ggatctggtg cagcctcggc
    20701 atcatcctgg cggtcgccgc acgccgcccg gacagccacg cccccgccct ccgggcggtc
    20761 ttcggcgccg tgttcctcgg gggagtggca cgtgggatct cgtacctcga cgtgggcgca
    20821 ccgcacgcca tgcacacggc cttcatcggt gtcgaactgc tcctgccgcc tctgatgctg
    20881 ttctggtaca cccggatcca cccgacgctg tagattcacc ggcgagcggg cgcgcctcac
    20941 ggggggaggc gcccgggtgg aagagcagtg gtgttggcgt ggaggtatgg ctgtgttgat
    21001 ggtgggcaag atccttcggt tcgacgaggt ccgcggttac gggttcatcg tccccagaga
    21061 ggggggcgag gacgttttca tgcacgcgaa cgacctggtg gacgacaagt acctgtacca
    21121 ggcgggccgc gaggtcgagt tctacctgga gatgggtgac aagggcccca aggcgtccga
    21181 gatccggctg gtcgagc
//
