LOCUS       NZ_LIYH01000003        22581 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000003
VERSION     NZ_LIYH01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 941528)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941528)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 225563
            Orig. end                         :: 248144
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22581
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22581
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22581
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12581](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12581
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(57..69)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(248..745)
                     /locus_tag="AMK26_RS14230"
                     /old_locus_tag="AMK26_14045"
     CDS             complement(248..745)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984231.1"
                     /locus_tag="AMK26_RS14230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14045"
                     /product="nitroreductase/quinone reductase family protein"
                     /protein_id="WP_073754988.1"
                     /transl_table=11
                     /translation="MTPPRTEPHRSKPLAGWRNRLHRAPLHLYRIGLGSLFGRHLLLMY
                     AHRTSGVTRKAVLEVVAHDPQVPAWTMASRVDPTAEWYRDLRMTPKVTIQFGSRYHAVT
                     AHFVPTAEGDRIMARYAMARPRLTKRLCVFMGLLDDSMEEMRGTDASVLFVRLCGPGRE
                     GH"
     misc_feature    815..835
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.59"
                     /tool="antismash"
     gene            911..1969
                     /locus_tag="AMK26_RS14235"
                     /old_locus_tag="AMK26_14050"
     CDS             911..1969
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948928.1"
                     /locus_tag="AMK26_RS14235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14050"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_073755502.1"
                     /transl_table=11
                     /translation="MAEAALRRSSLLPVMPYMVMALVAVIDVTAGPAVGFLPLVSLGPA
                     FAGLVGGWRRTAVIGGLALFLCLGLAWYDGLLPGRRGFTALASVAGVTGAGLLAAIMRQ
                     RREAEFAGVRAIAEVAQRVLLRPVPCRAGRLRVAVSYNSALAGARIGGDLYEVVASPSG
                     VRVIVGDVQGKGLEAVETAAVVLGVFREAAHDEPDLRSIGLRLERAADRELYGEKFVTA
                     ALAEVGDDGRVTLLNYGHPSPVVVRLDGTVRLAEPPRNALPLGLGVLGTQRPEPYETDL
                     ATGDQMLFYTDGVTEARDRRDRFYPLTERALLLMAPDPETALERLRTDLVAHVQGPLQD
                     DAAMLLLRYQEG"
     gene            2041..2574
                     /locus_tag="AMK26_RS14240"
                     /old_locus_tag="AMK26_14055"
     CDS             2041..2574
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948927.1"
                     /locus_tag="AMK26_RS14240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14055"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_073754989.1"
                     /transl_table=11
                     /translation="MAERTQPPQGIDDVDAVTRAVLTASRLLVAVSARSLAAVEDRVTL
                     AQFRLLVVLSTHGSAKLVVLADRLGVNPSTAMRMIDRLIAAGLADRQINPANRRETVLQ
                     LTDEGRRLVEHVTSKRRQEIATIVERLAPEQRSALIDALTAFTEAGGEPPVEAGERGPL
                     HPLGWADIPTGRDE"
     gene            complement(2800..2991)
                     /locus_tag="AMK26_RS36655"
                     /old_locus_tag="AMK26_14060"
     CDS             complement(2800..2991)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS36655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_14060"
                     /product="hypothetical protein"
                     /protein_id="WP_143608520.1"
                     /transl_table=11
                     /translation="MAYAANDPEGKKILGLIVGIVAAKSYNCYASFMDPRNATVTTIRL
                     VDVFVTLLGMGWVSASFP"
     misc_feature    complement(2997..3014)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(3287..3508)
                     /locus_tag="AMK26_RS14245"
                     /old_locus_tag="AMK26_14065"
     CDS             complement(3287..3508)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS14245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_14065"
                     /product="hypothetical protein"
                     /protein_id="WP_143608523.1"
                     /transl_table=11
                     /translation="MRVIPLLIGIGCLMFSLAMVKNHRGFADRMLESRINLAPGEANTA
                     LVFRVVSYFFVVIGVLATSFGVVFLIFS"
     gene            complement(<4417..>7498)
                     /locus_tag="AMK26_RS14250"
                     /old_locus_tag="AMK26_14070"
                     /pseudo=""
     CDS             complement(<4417..7498)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521856.1"
                     /locus_tag="AMK26_RS14250"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="AMK26_14070"
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRDDSGDPGYSEGTSFSGRSLTQAWRWNLDYVEDTSGNAATYWYT
                     KEINHYKKNKATTANAPYVRGGYLTEIKYGLRKDALFVDDADAKVTSPMPSAVPPRTAR
                     R"
     misc_feature    complement(6332..6334)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7950..7962)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: medium, score: 24.14"
                     /tool="antismash"
     gene            7965..8669
                     /locus_tag="AMK26_RS14255"
                     /old_locus_tag="AMK26_14075"
     CDS             7965..8669
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890963.1"
                     /locus_tag="AMK26_RS14255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14075"
                     /product="hypothetical protein"
                     /protein_id="WP_241837891.1"
                     /transl_table=11
                     /translation="MSSGRHRAHRAPGKPIRSVLWGPAAYDGRPPGWLVVEGLTVGVVG
                     AAAIATPGIIGVLADSVALRTGEAGVVVAAGLAVYLAVTGAGRALVGVAAVLGVFWGLL
                     TPRAVTEAVLLWDGEVRSVVVTSVAPIGDATTGRRYCSVRHMDGTPVSVRIWRGCERTT
                     GPGDHISLVSDPKGRVPPRGVPASGSLAQPLTETAGTGLLLVTVSAVAAVRSYRLAPDS
                     HPMPAPDAPQPA"
     gene            complement(8760..9065)
                     /locus_tag="AMK26_RS14260"
                     /old_locus_tag="AMK26_14080"
     CDS             complement(8760..9065)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS14260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_14080"
                     /product="hypothetical protein"
                     /protein_id="WP_073754992.1"
                     /transl_table=11
                     /translation="MSTLAITGWGVLTPVGTGADEITAVWRERQPGLRAVGGMYDEALP
                     NEKACAITDFDVRDHLGRKGNTSPTRLPGTPQRTLQGPSASITGACRAPAVVPRCR"
     misc_feature    complement(8826..8828)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9244..9260
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            9259..9456
                     /locus_tag="AMK26_RS14265"
                     /old_locus_tag="AMK26_14085"
     CDS             9259..9456
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982245.1"
                     /locus_tag="AMK26_RS14265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14085"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_241837892.1"
                     /transl_table=11
                     /translation="MRRRRLNAQALADRTGIRTPRIRVFAEEGAHGPVRPTRLELAELA
                     DALALPLSAVLEAARTPAAA"
     misc_feature    complement(9583..9597)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    9584..9595
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.52"
                     /tool="antismash"
     misc_feature    9694..9703
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     gene            9864..9974
                     /locus_tag="AMK26_RS36170"
     CDS             9864..9974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656044.1"
                     /locus_tag="AMK26_RS36170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_107420947.1"
                     /transl_table=11
                     /translation="MKKAYEAPTLVRLGTFRKKTGLLNSSGNDRLVLSKN"
     gene            10001..11857
                     /locus_tag="AMK26_RS14270"
                     /old_locus_tag="AMK26_14090"
     CDS             10001..11857
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602539.1"
                     /locus_tag="AMK26_RS14270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14090"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_073754994.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.6e-48, bitscore:
                     160.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELHASAGTGPGDAHFAVFTDREDAAAVARSFALPGTRTLQHAS
                     GRPWLVGQWDDQELVSAHTRRAALAVIGCCPVDAAELERHAGRLRDLAELDALARSLPG
                     SFHLVATLDGRLRVQGTASGLRLVFHAAVDGVQVAATRADVLADALGTAPDEQRLAVRL
                     LWPVPYPLFEASLWRDVTAVAPHDALVIGADGHSARHSRWWTPPEPVRTLADGAPLVRE
                     ALTEAVGARTRHGGVVSCDLSGGLDSTSICFLADRSPARVVASTWPGRDPADTDLYWAE
                     QAAKHLPDVEHVVWDADASPLVYDDLLAIDDLLDEPTIGVMDRSRVLHHLPGMAERGSR
                     LHLTGIGGDHVAWCSEAYYHRLLRTRPLFALRQLRGFRALWQWPLGGTVRALADSRPYG
                     KWLADRSGRLRDPVPATVTTSLGWGMPPRLFDWVTPDAERLARRALREAAATATPLHPD
                     RGLHTDLEQIRSCTRIIRQWDRMAARAGVPMASPFLDDRVIEASLAVRPSERVSPWQYK
                     PLLTAAMRGIVPEVCLRRTNKAAASMDAADGLRRHRADLLAMWEDSRLEQLGLVDGEAL
                     RGLAQRPSTPALRDAVLYSTIATEVWLRGLSRTPTRTRTRTR"
     aSDomain        11887..12060
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AMK26_RS14275_Lasso_Fused_RRE.1"
                     /evalue="2.00E-08"
                     /identifier="RREFam003.1"
                     /label="AMK26_RS14275"
                     /locus_tag="AMK26_RS14275"
                     /protein_end="58"
                     /protein_start="0"
                     /score="25.2"
                     /tool="antismash"
                     /translation="MALRFRPDVSTAETQYGTVLLDERSGNYWELNPTGTLVVKTLLGG
                     GDETSAVEALLAE"
     gene            11887..12141
                     /locus_tag="AMK26_RS14275"
                     /old_locus_tag="AMK26_14095"
     CDS             11887..12141
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309239.1"
                     /locus_tag="AMK26_RS14275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14095"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_073754995.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 5.7e-07,
                     bitscore: 25.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.9e-27,
                     bitscore: 90.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-17, bitscore: 59.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALRFRPDVSTAETQYGTVLLDERSGNYWELNPTGTLVVKTLLGG
                     GDETSAVEALLAEFDIDRVRAEQDVTALVQELRTSGLAS"
     aSDomain        11890..12135
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AMK26_RS14275_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.90E-29"
                     /identifier="RREFam002.1"
                     /label="AMK26_RS14275"
                     /locus_tag="AMK26_RS14275"
                     /protein_end="83"
                     /protein_start="1"
                     /score="90.7"
                     /tool="antismash"
                     /translation="ALRFRPDVSTAETQYGTVLLDERSGNYWELNPTGTLVVKTLLGGG
                     DETSAVEALLAEFDIDRVRAEQDVTALVQELRTSGLA"
     gene            12138..12581
                     /locus_tag="AMK26_RS14280"
                     /old_locus_tag="AMK26_14100"
     CDS             12138..12581
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988507.1"
                     /locus_tag="AMK26_RS14280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14100"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_073754996.1"
                     /sec_met_domain="PF13471 (E-value: 6.9e-24, bitscore: 79.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALERPIGVPFTRRLAARLVLLPAVALSLLSPRRIRAVLGV
                     VRRGAAPATAAQAQNARDAMCAVSLLCAGPKGCLPRSLGAALLCRLTGSWPTWCTGASV
                     VPPFNAHAWIEAEGRPIGEGVPDDYFRRLLAVGPVTANRPPSP"
     gene            12578..14422
                     /locus_tag="AMK26_RS14285"
                     /old_locus_tag="AMK26_14105"
     CDS             12578..14422
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987088.1"
                     /locus_tag="AMK26_RS14285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14105"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073754997.1"
                     /transl_table=11
                     /translation="MTGPRAEVPDRSTRAAVATMYRLTTGHRTSIVVATVLTLVGSALG
                     LAQPLVAKQIVDMSGHGRVFWPLLLLLAVLFVTEAATGAIGRFVLERMGEGVVRQLRHG
                     LVGRLLRLEMREYDRHRSGDLISRVTADTTLLREVVSQALVDLVTGALVAAGAVALMLW
                     IDPLLLVLVTLTVATAAAVVASLLKGIRAASEHMQNSVGAIAADLERALGALPMVRVHR
                     AEEREARRIGERIESAHDAGVRTARLASVMSPAVELAVQGSFLLVLVIGGLRVTGHANS
                     LGDLVAFLLYASYLVLPLSSVFRAVGLIQRGMGAYQRIEHALSLPAEPSLPRRPAVRAR
                     TREPARQAAADEEPALALRDLTFGYDPDRPVLRGVTLTVPHRRQTALVGRSGAGKSTIF
                     ALVARFYEPDSGALLFDGRPACELTRAECRARIAVVDQNTHVVHGTLRDNITYAVPDAP
                     EAEVRRVVELAQLDDVVRRLRGGLSGLLGERGSTLSGGERQRVALARALLGRPQLLLLD
                     EPTSHLDAINETALTKVMKDIAGECALLVIAHRLSTVQHADQIVVLDNGRTTACGRHEE
                     LLTCSPTYRELAAGQMLRPAAAPPPPAATARTRPHGKR"
     gene            complement(14457..15020)
                     /locus_tag="AMK26_RS14290"
                     /old_locus_tag="AMK26_14110"
     CDS             complement(14457..15020)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847720.1"
                     /locus_tag="AMK26_RS14290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14110"
                     /product="hypothetical protein"
                     /protein_id="WP_198944066.1"
                     /transl_table=11
                     /translation="MSVTSVLHRPASPEERRRMIRRRILTAVVIVLLIGIPAGYLVISA
                     QQSRASGRDKEAESSVTGLRDSWPSKMKRRVFEVPIPAGSTEVAYFETSNWKSSRLYVE
                     FTTDGTGLDDFLNDVGTSRAALDAKDITISDRDARTVGWTFPAGRDWSATTHRQKDPRP
                     TQDITVDLTDPAAPRVYVVSTATP"
     gene            complement(15023..16183)
                     /locus_tag="AMK26_RS14295"
                     /old_locus_tag="AMK26_14115"
     CDS             complement(15023..16183)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890407.1"
                     /locus_tag="AMK26_RS14295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14115"
                     /product="ROK family glucokinase"
                     /protein_id="WP_073754998.1"
                     /transl_table=11
                     /translation="MSTYRDLAHRGSARATVLRTVSARERRSHLTAPRVPTVGIDIGGT
                     KVMAGVVDADGRILEQIKTETPDKSKSAKVVEDTITELVLDLSDRHDVHAVGIGAAGWV
                     DADRSRVLFAPHLAWRNEPLRDSLQARLAVPVMVDNDANTAAWAEWRFGAGRGEDHLVM
                     ITLGTGIGGAILEGGQVKRGRYGVAGEFGHMQVVPGGHRCPCGNRGCWEQYSSGNALVR
                     EARELAAADSPVAYNIIERVKGSVPDITGPLITELAREGDAMCIELFQDIGQWLGVGIA
                     NLAAALDPSCFVIGGGVSAADDLLIGPARDAFRRHLTGRGYRPEARIAKAQLGPEAGMV
                     GAADLARLVARRFRRANRRRLERYEKYERYAQAIRNGRTTTTTQEP"
     gene            complement(16297..17115)
                     /locus_tag="AMK26_RS14300"
                     /old_locus_tag="AMK26_14120"
     CDS             complement(16297..17115)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944452.1"
                     /locus_tag="AMK26_RS14300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14120"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_073754999.1"
                     /transl_table=11
                     /translation="MTALVELADVSKYYGNIRALEGVSLEVHAGEITCVLGDNGAGKST
                     LIKIIAGLHAHDGGTFRIEGEETSLSSPREALDRGIATVYQDLAVVPLMPVWRNFFLGS
                     EPTKGAGPFKRLDVDLMRETTRAELLRMGIDLRDVDQPIGTLSGGERQCVAIARAVYFG
                     AKVLVLDEPTAALGVKQSGVVLKYVAAARDAGLGVVLITHNPHHAYLVGDRFVLLKRGV
                     MAASHTKDSVTLDELTRQMAGGSELEDLRHELERAPSPARVGGHEVPPAP"
     gene            complement(17112..18167)
                     /locus_tag="AMK26_RS14305"
                     /old_locus_tag="AMK26_14125"
     CDS             complement(17112..18167)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944453.1"
                     /locus_tag="AMK26_RS14305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14125"
                     /product="ABC transporter permease"
                     /protein_id="WP_073755000.1"
                     /transl_table=11
                     /translation="MTTTAPPVKDGSPVDERLLRTSPLRGLLGRPELGSVVGAVAVFLF
                     FSIVADSFLRASSFGTVLYAASTIGIMAVPVALLMIGGEFDLSAGVLVTSSALVSSMFS
                     YQMTANIWVGVLVSLLVTLAIGVFNGVMLTRTKLPSFIITLGTFLMLTGLNLGLTKLIS
                     GTVSTRTIADMEGFGSARALFASQFSLGGIDIKVTILWWFGLVALATWILLRTRFGNWI
                     FAVGGGADAARAVGVPVRTTKIGLYLGVAFCAWVSGQHLLFSFDVVQSGEGVGNELIYI
                     IAAVIGGCLITGGYGSAIGSAVGAFIFGMTSKGIVYAEWNPDWFKFFLGAMLLLATLLN
                     AWVRKRAEATK"
     gene            complement(18164..19189)
                     /locus_tag="AMK26_RS14310"
                     /old_locus_tag="AMK26_14130"
     CDS             complement(18164..19189)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003954479.1"
                     /locus_tag="AMK26_RS14310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14130"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_073755001.1"
                     /transl_table=11
                     /translation="MARVRTGVRALRAVLATVLGVSLAGAAAGCSATGGKRAEDARKAA
                     AAEGRAAVNTPRWTIAMVTHSGDGDTFWDIVQNGAKQAAVKDNITFLYAHSDEGQQQAQ
                     LVDSYIDKKVDGLIVTLAKPDAMKASVARAVKAGIPVITVNSGSEQSKAYGALTHIGQD
                     ENIAGEAVGDELDERGRKKALCVLHEQGNVGHEQRCAGVKKTFDGDVQNLYVDGTNMPD
                     VQASIEAKLQTDRSIDAVVTLGAPFADAAVQAKRTAGSDAEIDTFDLNAKVAAGLKSRQ
                     LGFAVDQQPYLQGYEAVDLLWLHRYNADVLGGGRPVLTGPQIITEKDAAKLAEFTERGT
                     R"
     gene            complement(19279..20283)
                     /locus_tag="AMK26_RS14315"
                     /old_locus_tag="AMK26_14135"
     CDS             complement(19279..20283)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944455.1"
                     /locus_tag="AMK26_RS14315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14135"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_073755002.1"
                     /transl_table=11
                     /translation="MRTTRTAAAALLTAVALTVTAAGCSSSGGKDSENKATHTSGGGKP
                     AATPRMTVAMVTHSGEGDTFWDIVQSGAKAAAAKDNVEFLYAANKEGKEQAALIDSYVT
                     KKVDGLIVTLAKPEAVKASVAKAVAAGIPVVTINSGGQHSKAFGALGHIGQDEAVAGEA
                     VGDELTARGRKKALCVIHEQGNVSLEERCAGVRKTFKGIVENLNVEGTNMPAATSSIEA
                     KLQSAKDIDAVVTLGAPFAAASVKARQSAGSGAEINTFDLNAAVVAQLKAQQIGFAVDQ
                     QPYLQGYLAVDSLWLHKDNLNIIGGGKPVLTGPALVTEKDVPVLEELTARGTR"
     misc_feature    20365..20379
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.84"
                     /tool="antismash"
     gene            complement(20405..21124)
                     /locus_tag="AMK26_RS14320"
                     /old_locus_tag="AMK26_14140"
     CDS             complement(20405..21124)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888796.1"
                     /locus_tag="AMK26_RS14320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14140"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_073755505.1"
                     /transl_table=11
                     /translation="MDRTSPVPLYFQLSQQLEAAIERGTLTPGSLLGNEIDLAGRLGLS
                     RPTVRQAIQALVEKGLLVRRRGVGTQVVHSQVKRPLELSSLYDDLEAAGQRPATIVLTN
                     RIDPATAEVAAALGVPEGTDVRYVERLRFAHDEPMARLRNHLPLGLLDLDTELLEGTGL
                     YRMMRGAGITLHSARQKVGARAATSLEAELLTEEKGAPLLTMERTTFDDTGRAVEFGSH
                     IYRASRYAFEFQLLVRP"
     misc_feature    21250..21270
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.69"
                     /tool="antismash"
     gene            21290..22297
                     /locus_tag="AMK26_RS14325"
                     /old_locus_tag="AMK26_14145"
     CDS             21290..22297
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309748.1"
                     /locus_tag="AMK26_RS14325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_14145"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_073755003.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 7.6e-19, bitscore:
                     64.2, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2.4e-26,
                     bitscore: 87.7, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLIGTGRIGAFHAGVLSRHREVGALVVADADPGRAAQVADLT
                     GATAAPTVDDVFARGVDAVVIASATAAHAELIGRAARAGLPTFCEKPIALDLPGTLGAL
                     REVEAAGTQLQLGFMRRFDAGYRAARDAVHSGRIGRLHTVRAITSDPAPPPAAYLPLSG
                     GLYRDCLVHDFDILRWVTGREVTEVYATGSDGGPAMFREAGDVDTAAALLTLDDGTLAT
                     ATATRCNGAGYDVRMELAGERDQIAVGLDDRTPLTSTEPLGPPAADKPWPGFLERFAPA
                     YEAELDAFVHLARGELANPCDGHEALQALRVAEACELSRRERRPVRLEEVPSAL"
     misc_feature    22467..22485
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.99"
                     /tool="antismash"
ORIGIN
        1 ccgccgggct ggccgaggct tcgccaccgc cgcttcgtac ggagatcaac agtgtggtga
       61 cggcggcaca gatcgctacg acgatcgcca ccgttcgcat tgcggtcagg ggccggattg
      121 cctttcggct cgggcgcatg atgcctcctt ctctgacttg gagagctgtt cgttcatatc
      181 gcccggaagc tgttgtcgcg gctggcacgg cgcgcagcag gaggtacgga tgcctgcgcc
      241 gagatgttca atggccttct cgcccagggc cgcacaggcg cacgaagagc acggacgcgt
      301 ccgtcccacg catttcctcc atggaatcgt cgagcaaccc catgaagacg cagaggcgtt
      361 tggtcagtcg ggggcgtgcc atggcgtaac gggccatgat ccggtcgcct tcagcggtcg
      421 gtacgaaatg cgccgtgacg gcgtggtagc gactgccgaa ctggatggtg actttgggcg
      481 tcatgcgcag atcgcggtac cactcggcgg tggggtcgac gcgggatgcc atcgtccacg
      541 cagggacctg agggtcgtgc gcaacgactt ccagcacggc cttccgcgtc accccgctcg
      601 tgcggtgtgc atacatgagc agcaggtgcc tgccgaagag cgatcccagg ccgatccgat
      661 acaggtgtag gggcgccctg tggagccgat tgcgccatcc ggccagaggc ttggaacggt
      721 gcggctcggt acgcggtggt gtcatagctc gtgcctttat gtgctggtcg actgcggttc
      781 ggtaacaggc agtggaagga tgcttcggcc cggaaagttt tgcataggct aaagttctgg
      841 gtcgtctgcg acgaagtgcc aggcggctgg ggaagtgacg ggcacagcag ttcagatcgg
      901 gggtgcggtc ttggccgaag cggcgctgcg gcgttcttcc ctgctgccgg tgatgccgta
      961 catggtcatg gcgctggtcg cggtcatcga cgtcaccgct ggacccgcgg tcggtttcct
     1021 gccactggtg tccttggggc cggccttcgc gggactggtc ggcgggtgga gacgaacggc
     1081 agtcatcggt ggtctcgcgc tgttcctctg cctcggactc gcgtggtacg acgggctact
     1141 ccccggacgc cggggcttca ccgcgcttgc ctcggtggcc ggagtgacgg gagccggtct
     1201 gcttgccgcg atcatgcggc agcggcggga agccgagttt gccggtgtac gggcgatcgc
     1261 ggaggtggcc cagcgggtac tgctgcggcc cgtgccatgc agggctggcc gtctgcgcgt
     1321 ggcggtgtcg tacaactcgg cgcttgcggg tgcccgcatc gggggggacc tgtacgaggt
     1381 cgtagcctcc ccctcgggcg tccgggtgat cgtcggagac gttcagggaa agggcctgga
     1441 ggcggtcgag acggcggccg tggtgctggg tgtcttcaga gaggccgccc acgacgaacc
     1501 ggatctgcga agcattggcc tccggctcga gcgggccgcc gatcgggagc tgtacggcga
     1561 gaagttcgtg accgccgcgc tggccgaagt gggcgatgac ggacgcgtca ccttgctgaa
     1621 ctacggacat ccgtcacccg tggtggtacg cctggacgga acggtgcgcc tcgccgaacc
     1681 gccccgcaac gcgctgcccc tcggtctcgg cgtactgggc acgcagcgac cggagccgta
     1741 cgaaacggac ctcgccaccg gtgaccagat gctgttctac accgacggcg tcacggaagc
     1801 cagggaccgc agggatcgct tctacccgct gacggagcgg gctctactgc tcatggcacc
     1861 ggacccggag acggcgcttg agaggttgcg caccgacttg gttgcgcacg tccagggacc
     1921 tttgcaggac gacgctgcca tgctgttgtt gaggtaccag gagggctgat accgaagtcg
     1981 ggccgtcccg ccgcgggggc ggacgcagcg tcacgacaga gacacggtag aaatgggggc
     2041 atggccgagc gaacgcagcc cccgcagggc attgacgacg tcgatgcggt gacccgtgcg
     2101 gtcctgaccg catcacgcct gctggttgcg gtctcagcgc gctctctggc cgccgtcgaa
     2161 gaccgggtga cgctggccca gttccgtctg ctggtcgtcc tgtccacaca cggctcggcc
     2221 aagctggtgg tactcgccga ccggcttgga gtcaatccat cgaccgcgat gcgcatgatc
     2281 gaccggctga tcgcggcggg actcgcggac cgacagatca accccgccaa ccgtcgcgaa
     2341 accgtcttgc agcttactga cgagggccgt cggctcgttg agcacgtcac atccaaacgc
     2401 cggcaggaga tcgccacgat cgtggagcgc ctggcacccg aacaacgctc cgcattgatc
     2461 gacgcgctca ccgcgttcac cgaggcaggc ggcgagccgc ccgtggaggc gggtgaaagg
     2521 gggccgcttc atccgctcgg ctgggcggat attcccacag gccgggacga gtgagcggct
     2581 actccggccc acttcctctg tattactcga agcaccctcc cacgcggaag acctcttacc
     2641 acgtccagcc ttcttggctg cccgaacctt ccggcccacc gcatgggcgc cgaaggaaag
     2701 tagctccggc gcccatgcga atcccgtgag cggctggcta tcgcgtggag aatgagcctg
     2761 cgacccagcc ggagcctccc tttgcggatg gcgtccaagt caggggaacg atgcactcac
     2821 ccatcccatc cccagcaggg tcacgaatac gtcgaccagg cggatggtgg ttaccgttgc
     2881 attccgtggg tccatgaaag acgcgtagca gttgtagctt ttggcggcta caatcccgac
     2941 gatcaagccc aagatcttct tgccctcagg gtcgtttgcg gcgtaagcca cgtccctatc
     3001 cgctccagat catcatccat cagaacccag cgccccggtc gtgggcaacg gaagccggtc
     3061 ccgccaactg gtccgacagc cgccgaaccg cccgcattcg gatgtcgtgc tgcccccgac
     3121 tacaaccgag ccagcccgaa catcagcacc agcaggccga tcacgatcca cagaaatccg
     3181 gccattctta gcaggcgaac tctcctcgga cgcgccgcaa cagcgatccc ggcaacgagg
     3241 cataccgacc cgaataccac atgaaacccc gtgacgacgg ccgccatcat gagaagatga
     3301 gaaacactac gccgaatgag gtggccaata ccccgatcac cacgaaaaag tagctcacca
     3361 cacggaacac caaagcggtg tttgcctcac ccggggcgag gttgatgcgc gactccagca
     3421 tccggtcggc aaaaccgcga tgatttttta ccatcgccaa ggaaaacatc aggcaaccga
     3481 tgccgatgag cagagggatg accctcatct cgcacgtccc tttcgtcatt aaccacattg
     3541 acgcgccggc ttcggcccgc acacttcggt gggcgggtcg aagccgatgc tcaagactca
     3601 actacatccc aggttccagg aacatcccca ggtgtagttg atacctgact cgacgccgcc
     3661 ctccatgccg acccctcctc cggtctgaag accccagacg ggctcaccct tgtcgttcct
     3721 cacccaggat ccgtcgaggt tgaacgagct ctcgtggttc acgaccgctc cgacaatgta
     3781 gtggcccgag acttccttgt cccagcccca tcctcggagc tggttcagct tgtccgcgtt
     3841 gctcgtcagg acagtggcat cgccagaaaa gcccgctccc actccggaca gcgcaggcga
     3901 cagactcgca ccgaagtccc actcgtcgtg agagttttta ccggcaagga agcacacttc
     3961 cagtgtcccc atcaccacag caccgccgga gccgctcaga cagactccca tggtgttggt
     4021 ctccgtgccg acaccaacca catcaagaac ttggtcgaac cagcccttct tcggttccgg
     4081 cttcgggggc gggccagggt tcggaggcgc ttgcggcagc cagccggccg gggcgggcgt
     4141 ggccggcacg gtgatgttgc ggcggccacc ggttccgccg ctggtgtgga gaccggtggg
     4201 cttgccgttg ctgtcgacga gcggagggcg cttaccgcag cggcacgcgc ggttgccgtc
     4261 gttgctgctc ggctgcggct tacgcgtcga cggcaggtgg accgggatgc cgccgcggca
     4321 ttcgatcagc ccctgcatgc actccggcac cgcaagcccg gtggcgtcgg tgaacgtcgt
     4381 cgggttgttg ttggcgtagg cgtacccgtt caggcagacg atttcctggg gcagtccgcc
     4441 gagtgccggc tgcgtgctgt tctgcagggt gccgtcgagg cggtagctcg tggcgaggtc
     4501 gatggtcgcc ggggccccgg cggcgacgag cggctcgtcg gccggcaact gagccgcgta
     4561 ccggtggggc gggagaggtt gtcataggcg gtgaccgact tggtgtacgc ccgtcccgcc
     4621 ttgcctccga cgtagcgggt gctggaggca ggcagcccct tgagaaccgt gtcgtaggtg
     4681 gaggaggtca gttgcttggc gtcggtcttc tcaccggacc aggtgccgat gccgcgcccg
     4741 agttcgtcgt actcactcaa aatgctcctg ccgcgtgagt ccgtggcttt gatcacccgg
     4801 tccaggacgt cgtagccgag ggtggtccgg cccttgtccg ggtcgtggga ggtcatgaac
     4861 cgaccgaaca ggtcataggc gctggtccag gttgtgccgt cggggccggt ggtcgacttc
     4921 ttcttgccgt cgaggtcgta ggcgaacgcg gtagtggtgt agccgttgcc gaggctgccg
     4981 ccgaactggg tgtccgccgg gctcgcgccc gcatagctcc gggtctcggt cgtgcggccg
     5041 cgggcatcgg tgatcgtccg gctggccgtg ccgccctgga gagcagtggt cgcggtggag
     5101 tcaccggtgt aggacgtcgt tgtcgaccac ttcttcacgc cgtacacgta gagcgtgctg
     5161 gtggtggcgc gctccgcccc gtcgtaagcg gtctcggtct gcttcggcgc cccgccgtat
     5221 tcggcgcggg tgtaggtgcc gttggggaga gtcgtgttgt cgtagatgtc ctcgtacgtc
     5281 tcgtaggcca agccacggga gtcgtaccgc gtgtcggtca gcagtcgtcc gcccagcgga
     5341 gtgggcgact gggtctggac ggctcgcagc agtgcgtcgt agatggcgta ggtggtgttg
     5401 taggtctgcc cgtccgcctt cagggtcccg gtcgagaccc aggacgcttt ggcgttggaa
     5461 aggaagtacc ggtactggta gttggggctg tcaccggcgg ccttgttgcg attgggcagc
     5521 cagacatctg tccggcggcc aagagcgtca taggcggttt cggtcttctt caggttggcg
     5581 tcgtacaccc ggttcggctg gccgcgccgt gggtcgatga agctggtagt cctgtggccc
     5641 ttggcgtttg tgacgatcgt tttcgtcagc ggtcccgccg tggttggcgt gtaggcagtc
     5701 gaggtgacct tgcccgcggc gtcggtgacg gtcagcgggc ggccgagtgc gtcgtgagtt
     5761 gtcgttgcga cggtctgcca gctgggtgtg gtggcgctgt agcccttggc ccggccggtc
     5821 cacgtcgcca gccccttggt cggcttcatg gtcgtcgacc aggcgacacc gtcgtatgcg
     5881 gtggcggtgt cagacaggac atcgccacgg cgtgtggtgt ctgccggcag gtcgagggac
     5941 gtgtcggcga catcgcactt cttgccgacc gtgcgtgtac gggagatgag gttcgtcagc
     6001 cccgccgcgt catcgcgcgc gtaccaggta cgggtgcagg tctcatcccc ggtcttggca
     6061 tcatcgccga gatcgtcgac acggtagggg tgtccgtagt tgtcgtatgc ggtctggact
     6121 gtgcgggacc gccagctgcc ggatgctgtg aggtaggtgt ggctggtgtt cttggctacc
     6181 cgaacgtagc gggccacggc gtcgggcgca tcgggctggc tctggcgtgc ggtctccttc
     6241 gaccacggct cgttggactc cgcggagatg gctgtggagc cgttgtaggt cactcgctgg
     6301 cgcagttggc cggcgtactg gtcgctgtcc ttaagggtgg cgaggcccag agcgggggtg
     6361 gtcaggggag cgatgctgac cgtttttgtc gtgccgtcct tgttcttgtc gccgtccatg
     6421 ccctgcatgt agagggagac ggtcttggag cgggtggcgt ccttggcacc gttgtagacg
     6481 gtgacctgcc ggtagccacg ccactcggac caggtgcgtt catccttggg cgagaacgga
     6541 ctgtcgctgt ggctccatgc cgcaccgctg tagacgtact tttgctcgag cacatcgttc
     6601 cgtcccgctg ggtccgaggt cgtcacggcc agcacccggt acttgtggaa ccagtcgatg
     6661 gaggcttcgc tcgcgccgtt gatgttccag tactgaggga agcagttgcg ggtgttggtg
     6721 tcctcggcgg tgcccgtcac ctcgctgcgc acgcattccg gggcggagag ggtgaccgtg
     6781 gtgatggccc ctgtctcgga ggtgatcgtg gagacgcggg gtcgggtcag agggaggatg
     6841 tcgtcagtgc cgtcgacccg gttctgccgc atctggtacg tgaactggat cgggtccatc
     6901 gcgatggcgg agccggcctt gccggtccgc ttgatggact tgagcgtcag gacgtggtca
     6961 gaggtgtctc cgatgtcccc gccatccagg tactgctgag tcaaggccca ggagtccacc
     7021 gggtcgtagg cgctgctggt ggcgttccag gagaaggtgt tgatgccggt gagacgcttg
     7081 cgggagaaga acgaggggcc ggtgcccagg cacgtctcgt ctccgctgga gcagatggcg
     7141 tcgaagggga catccggcca cttgtcggcg gtctccttgg tcagcgacgt gcagtccgcg
     7201 gcggtacagc gctcggcatg ggagaagtca ccttcgcgtc ggcgtcatcg acgaagaggg
     7261 cgtccttgcg aagcccgtac ttgatctcgg tcaggtagcc acctcgtacg tagggagcgt
     7321 tggcagtggt ggccttgttc ttcttgtagt ggttgatctc cttggtgtac cagtaggtgg
     7381 cggcgttgcc ggaggtgtcc tcgacgtagt cgaggttcca gcgccatgcc tgggtcagcg
     7441 accggccgga gaagctggtg ccctcggagt agccggggtc gccggagtcg tcacgccatg
     7501 ggtgatgaac caggagccgt cgcggccgcc gaggagcagc cggagctgac ggaggcgcag
     7561 caggcgcaga gcagccgaag gcgcggcttg tggccgagtt tgaagcgggg ctgccgttct
     7621 ggcggcaggc ggccgaggca accgacgcca cgcccttcct cggacacctt cgctcggtgg
     7681 agaaccactc cggaaacgcg cacacccggc ggatccgcgc tctcctgaac cttcccgctg
     7741 ccccgtccgc gccaggcggg gcagcggcag cgccggtgcg aaacacggcg ctccactgat
     7801 cgcgtaccca ggagatctca cgccacagaa cgccccgacc cctcttgtct gcagcgatgg
     7861 gtaaatcgat catcggttgg gcgtgaaacg tgtactggcc cggcggcgac tccagaacga
     7921 caggcggtgc gggtcggctc ggacgtggct tgcataatgc aagcatgagc agcggcagac
     7981 acagagccca ccgggcaccc gggaaaccga tccgttcggt gttgtggggg ccggctgcct
     8041 acgacggccg gccgcccggc tggctggtcg tggagggtct gaccgtggga gtcgtcggcg
     8101 cggccgccat tgccacaccg gggatcatcg gggtcctggc cgattccgtg gccttgcgca
     8161 caggagaggc gggcgtcgtc gtcgctgccg gactggcggt ctacctagct gtcaccgggg
     8221 caggacgggc actggtcgga gtggcggccg tacttggtgt cttctggggc ctgctcaccc
     8281 cgcgggccgt gaccgaagcc gtactgctgt gggacgggga ggtgcgcagc gtcgttgtga
     8341 catccgtcgc ccccattggc gatgcaacga cgggcaggcg ctattgctcg gtgcggcaca
     8401 tggacggcac accggtctcc gtgaggatat ggagggggtg cgagaggacg acgggcccgg
     8461 gagaccacat cagcctggtg tccgacccca aagggcgggt tcccccgagg ggagtgcctg
     8521 cctctggttc tctggctcag ccgttgacgg agacggccgg caccggtctg ctactggtca
     8581 ctgtcagcgc ggtggcggct gtccgctcct accggctcgc ccccgacagt cacccgatgc
     8641 ctgcgcccga cgccccccag cccgcctgac ccgctacgcg gtcatgtccg cgcgaccgga
     8701 cggtgccaca ggaccgagtg cagcgcttgc tgagtcccac agcggccggt cattgcccgt
     8761 taccggcagc gtggcaccac cgcaggtgcc cggcaggctc ctgttatgga tgcggaaggc
     8821 ccctgtaaag tccgctgcgg tgtgccggga agcctggtcg gcgaagtgtt gcccttgcgg
     8881 cccaggtgat cccgtacgtc gaagtcggtg atcgcgcatg ccttctcgtt cggcagggcc
     8941 tcgtcgtaca tgcctccgac cgcgcgcagg ccgggctgcc gctcccgcca gaccgccgtg
     9001 atctcgtcgg cgccggtgcc cacgggggtc agcacgcccc agccggtgat cgcgagcgtg
     9061 ctcatcccac ccacagagat ccggcacggg agaccgcgga tacgccggat ccagccgtat
     9121 tcgtcggggc cttccccgta tctggaaggg gaagcgggta cgggaccacg ccgatgcacc
     9181 gaacggcggg cggctgggcc ggcggatcag gggcagacga aggaaatggc cgaactttca
     9241 cagtcgttgc aacagaccat gcgacgtagg cgcctgaacg cgcaggctct cgccgaccgc
     9301 accggcattc gcaccccgcg gatccgcgtc ttcgccgagg aaggcgccca cggccccgta
     9361 cggcccaccc ggctggaact cgccgaactc gcggacgctc tggcactccc cctgtccgcc
     9421 gtcctggaag ccgcccgcac accggctgcg gcctgacccg atccggccag gagacgaagg
     9481 agaggaagcg cgggcgcatg ggtcgagtgc gccccggcgg ctccgtccgg tgaccgtccc
     9541 ggcctccccg cggcaggacc accacaggtt gcgtcacgga ggtggaaacg tttttccagc
     9601 ccgcccgcac gccggcctgg agtcgtgcgc ccttctccgg caccccctga ctggccgtga
     9661 gatgacatga tcacttgttt attgcatatt gtctgatttt ctaaggcgcc cttgtcatac
     9721 tgcccggttc tgcacctagc tagatgccgt gcccgcttcc cgccccgggt tcccatgagc
     9781 cttgggcagg ccggcagtga accggcgcct ccgtgcgccg gcggccaggg ggtgggcatg
     9841 aaacctgaac ctgaggagag gtcatgaaga aggcttacga agcgccgacg ctcgtccgtc
     9901 tcggtacgtt ccgcaagaag accgggctgc tcaacagctc cggcaacgac cggctcgtcc
     9961 tgagcaagaa ctgacgaccg acggtttctg acctgacgtc atgactgaac tgcacgcaag
    10021 tgcggggacg ggccccggcg acgcgcactt cgcggtcttc accgaccgcg aggacgcggc
    10081 cgccgtggcc cgctccttcg ccctccccgg tacgcgaacc ctccaacacg cctccggccg
    10141 cccctggttg gtcggacagt gggacgacca ggagctcgta tccgcgcaca cccgtcgtgc
    10201 ggccctggcc gtcatcggct gctgcccggt cgatgccgcc gaactggagc gccacgcggg
    10261 acggctgcgc gatctggcgg aactggacgc gctggcccgg tccctgcccg ggagcttcca
    10321 cctcgtcgcc accctcgacg gccggctgag ggtgcagggc acagcgtcgg ggctccggct
    10381 ggtcttccac gccgccgtgg acggcgtaca ggtggccgcc acccgcgccg acgtactcgc
    10441 cgacgcgctc ggcaccgctc ccgacgagca gcggctcgcg gtacggctgc tgtggccggt
    10501 gccctatccg ttgttcgagg cgtcgctgtg gcgtgacgtc acggctgttg ccccgcatga
    10561 cgcgctggtc atcggggcgg acgggcacag cgcacgtcac tcgcggtggt ggacaccgcc
    10621 ggagccggtc cgcacgctcg ccgacggcgc cccgctggtc cgcgaagccc tcaccgaggc
    10681 ggtcggcgcc cgcacccgcc acggcggtgt ggtcagctgc gacctgtccg gagggctgga
    10741 ctccacctcc atctgcttcc tggcggaccg ctcccccgcc cgcgtggtgg ccagcacctg
    10801 gccggggcgc gatccggccg acaccgatct gtactgggcc gagcaggcgg cgaagcacct
    10861 gccggacgtc gagcatgtcg tgtgggacgc cgatgcctcg ccgctggtct acgacgatct
    10921 gctcgccatc gacgacctgc tggacgagcc caccatcggc gtcatggacc gttcgcgggt
    10981 gctgcaccac ctgcccggca tggcggagcg gggcagccgg ctgcacctga cgggcatcgg
    11041 gggcgaccac gtcgcgtggt gctcggaggc gtactaccac cggctgctgc gtacgcgtcc
    11101 gctgttcgcg ctgcggcagt tgcggggttt ccgggcgctg tggcagtggc cgctcggcgg
    11161 caccgtccgt gcgctggccg actcacggcc gtacgggaag tggctcgccg atcgcagtgg
    11221 caggctgcgc gaccccgtcc ccgccacggt caccaccagc ctcggatggg gcatgccgcc
    11281 ccgtctcttc gactgggtga cgcccgacgc ggaacggctg gcgcggcgag ccctgcgcga
    11341 ggcggccgcg acggccacac cgctgcaccc ggaccgcggc ctgcacaccg acctggaaca
    11401 gatccgttcc tgcacccgca tcatccgcca gtgggaccgg atggcggccc gcgccggcgt
    11461 accgatggcc tcgccgttcc tcgacgaccg cgtcatcgag gcgtccctcg ccgtacggcc
    11521 gagcgagcgc gtgtcgccct ggcagtacaa gcccctcctg accgccgcca tgcgcgggat
    11581 cgtgcccgag gtctgcctgc ggcgcaccaa caaggccgcg gcctccatgg acgccgccga
    11641 cggactgcgc cggcaccgcg ccgacctgct ggccatgtgg gaggactcac ggctggagca
    11701 gctcggcctg gtcgacgggg aggccctgcg cggcctcgcc cagcggccct ccacccccgc
    11761 tctgcgcgac gccgtcctct actccacgat cgccaccgaa gtatggctgc gtggtctgtc
    11821 ccgcactccc acccgcaccc gcacccgcac ccgttaggcc cgcctcggag aaaggcagca
    11881 cacaccatgg cattgcggtt ccgccccgat gtctccaccg cggagaccca gtacggcacg
    11941 gtcctcctgg acgagcgcag cgggaactac tgggaactca atcccaccgg caccctggtg
    12001 gtgaagaccc tcctcggggg cggcgacgag acatcggccg tcgaggcgct gctcgcggag
    12061 ttcgacatcg accgggtccg cgcggagcag gacgtcacgg ctctcgtaca ggagctgcgg
    12121 acgtcggggc tggcctcatg acgacgccca gcgcgctgga acggcccatc ggcgttccgt
    12181 tcacccggcg tctggccgcc cgcctcgtac tgcttcccgc cgtcgcgctg tcgctgctgt
    12241 ccccgcgccg gatccgcgcc gtgctcggtg tcgtacgccg cggagccgcg cccgccacgg
    12301 ccgcgcaggc gcagaacgcc cgggacgcga tgtgcgcggt cagcctgctg tgcgccgggc
    12361 cgaagggctg tctgccccgt tcgctgggcg cggccctgct gtgccggctg acgggcagtt
    12421 ggcccacgtg gtgcacaggg gcgagcgtgg tgcccccctt caacgcgcat gcctggatcg
    12481 aggcggaggg ccggcccatc ggcgaaggcg tgcccgacga ctacttcagg cggctgctgg
    12541 cggtggggcc cgtgacggcg aaccggccgc ccagcccatg acgggtcccc gggcggaggt
    12601 gccggaccgc tcgacacggg ccgcggtggc caccatgtac cggctgacca ccgggcaccg
    12661 gacctccatc gtcgtggcca ccgtgctcac cctcgtgggc tccgcactgg ggctggccca
    12721 gccgctcgtc gccaagcaga tcgtggacat gagcggccac ggacgggtgt tctggcccct
    12781 gctgctcctc ctggccgtgc tgttcgtcac cgaagcggcc accggcgcca tcggccgctt
    12841 cgtcctggaa cgcatgggtg aaggggtcgt acgacaactc cgccacgggc tggtgggacg
    12901 gctgctcagg ctggagatga gggagtacga ccggcaccgc agcggcgatc tgatctcccg
    12961 cgtgaccgcc gacaccaccc tgctcaggga ggtggtgtcc caggccctcg tcgacctggt
    13021 gaccggggcg ctcgtcgcgg ccggtgcggt cgccctgatg ctgtggatcg acccgctgct
    13081 gcttgtcctg gtcaccctga ccgtggcgac cgcggcggcg gtcgtggcgt cgctgctgaa
    13141 gggcatccgg gccgcctcgg aacacatgca gaactccgtc ggcgcgatcg ccgccgacct
    13201 cgaacgcgcg ctgggcgcac tgccgatggt gcgggtgcac cgcgccgagg aacgtgaggc
    13261 gcggcgcatc ggcgagcgca tcgagtccgc tcacgacgcg ggcgtacgga ccgcgagact
    13321 ggcctccgtg atgagcccgg cggtcgagct cgccgtccag ggctccttcc tgctcgtcct
    13381 ggtcatcggg ggcctgcgtg tcaccggcca cgccaactcc ctcggcgatc tcgtggcctt
    13441 cctgctctat gcctcctacc tcgttctgcc tctgtcgtcg gtcttccgcg cggtcggcct
    13501 gatccagcgc gggatgggtg cctaccagcg catcgagcac gcgctgtcac tgcccgcgga
    13561 gccctcactg ccccgcaggc cggccgtacg ggcgcgtacg cgcgaaccgg ctcggcaggc
    13621 cgccgcggac gaggagcccg ccctcgccct gcgggacctc accttcggct acgacccgga
    13681 ccggccggtc ctgcgcggcg tcaccctcac cgtcccgcac cggcgccaga cggccctggt
    13741 gggccggtcg ggagccggaa aaagcacgat cttcgccctg gtggccaggt tctacgagcc
    13801 ggattcggga gccctgctct tcgacggacg gcccgcctgc gaactgaccc gtgccgagtg
    13861 ccgcgcacgc atcgccgtcg tcgaccagaa cacccatgtc gtccacggca ccctgcgcga
    13921 caacatcacc tacgccgtac cggacgcccc ggaggccgaa gtacggcgcg tcgtcgaact
    13981 cgcccagctc gacgatgtcg tacgccggct gcgcggcggc ctgtccggtc tgctcggcga
    14041 gcgcggcagc accctctcgg gaggtgagcg ccagcgcgtc gccctggccc gcgccctgct
    14101 cggccgcccc caactcctcc tgctcgacga gcccacgtcc cacctcgacg ccatcaacga
    14161 aaccgcgctc accaaggtga tgaaggacat cgcgggggaa tgcgccctgc tggtgatcgc
    14221 gcaccgcctc tccaccgtcc agcacgccga ccagatcgtc gtactcgaca acggccgaac
    14281 caccgcctgc ggacgccacg aggaactgct cacctgcagc cccacctacc gcgaactggc
    14341 ggccgggcag atgctccgcc cggccgcggc cccaccaccc cctgcggcga ccgcccggac
    14401 gcggccgcac ggaaagcggt gaacgggcgc gacggcgcga ggatgagccc tggcggtcag
    14461 ggggtcgcgg tcgagacgac gtagacgcgc ggggcggccg ggtcggtgag gtcgacggtg
    14521 atgtcctggg tggggcgcgg gtccttctgg cggtgcgtgg tggcggacca gtcgcggccg
    14581 gcggggaacg tccagccgac ggtgcgggcg tcgcggtcgc tgatggtgat gtccttggcg
    14641 tcgagcgcgg cgcggctcgt cccgacgtcg ttcaggaagt cgtccagtcc ggtgccgtcg
    14701 gtggtgaact cgacgtacag cctgctcgac ttccagttgc tcgtctcgaa gtaggcgacc
    14761 tcggtggagc cggccgggat ggggacctcg aagacgcggc gcttcatctt ggacggccag
    14821 ctgtcccgga ggccggtgac ggaggactcg gcctccttgt cgcggccgct ggcccggctc
    14881 tgctgggcgg agatcaccag atagccggcc gggatgccga tgagcagcac gatgacgacg
    14941 gcggtcagga tccggcggcg gatcatgcgc cgccgctcct cgggggacgc gggccggtgc
    15001 agcacggacg tcactgacat gactacggtt cctgggtggt ggtggtcgta cggccgttgc
    15061 ggatggcctg ggcgtaccgc tcgtacttct cgtagcgctc caggcggcgg cggttggcgc
    15121 ggcggaagcg gcgcgcgacg agccgggcga ggtcggcggc gccgaccatg ccggcctcgg
    15181 ggccgagctg ggccttggcg atccgggcct cggggcggta gccgcggccg gtgaggtggc
    15241 ggcggaaggc gtcccgggcg gggccgatca gcaggtcgtc ggcggcgctg acgccaccgc
    15301 cgatgacgaa gcaggacggg tcgagggcgg cggccaggtt ggcgatgccg acgccgagcc
    15361 actggccgat gtcctggaac agctcgatgc acatcgcgtc gccctcgcgg gccagctcgg
    15421 tgatcagcgg gccggtgatg tcggggacgg agcccttgac gcgctcgatg atgttgtacg
    15481 cgaccggcga gtcggccgcc gcgagttcac gggcctcccg gacgagggcg ttgccggagc
    15541 tgtactgctc ccagcagccg cggttgccgc acgggcagcg gtggccgccg ggcaccacct
    15601 gcatgtggcc gaactcgccg gcgacgccgt acctgccgcg cttgacctgg ccgccctcca
    15661 ggatcgcgcc gccgatgccg gtaccgagcg tgatcatgac gaggtggtcc tcgccgcggc
    15721 cggcgccgaa gcgccactcc gcccaggctg cggtgttggc gtcgttgtcg accatgacgg
    15781 ggacggcgag ccgcgcctgg agcgagtcgc gcagcggctc gttgcgccag gccaggtggg
    15841 gggcgaacag gacgcggctg cggtcggcgt cgacccagcc ggcggcgccg atgccgacgg
    15901 cgtgcacgtc gtgccggtcg gacaggtcca ggaccagctc ggtgatggtg tcctcgacga
    15961 ccttggcgct cttggacttg tcgggtgtct cggtcttgat ctgctccagg atccggccgt
    16021 cggcgtcgac gacgcccgcc atcaccttcg taccgccgat gtcgatgccg acggtcggca
    16081 cccggggcgc ggtcaggtgc gagcggcgct cgcgggcgga gacggtccgc aggacggtgg
    16141 cgcgggcgga gccccggtgg gcgagatcgc ggtacgtgct cacgagtcct gtcgtccctg
    16201 gtgggtgggg ccggcggcgg gcgcctccgg cggcggacgg cgcccgccgc cctcgattct
    16261 gccaggtacg cggccggggg cggcggtacg ccgtggtcag ggcgccgggg ggacctcgtg
    16321 gccgccgacg cgggcgggtg acggggctcg ttccagctcg tggcggaggt cttcgagctc
    16381 gctgccgccc gccatctggc gggtgagttc gtcgagcgtg acggagtcct tggtgtggct
    16441 cgccgccatc acgccccgct tcagcagcac gaaccggtca ccgaccagat acgcgtggtg
    16501 cgggttgtgc gtgatcaaca ccacgccgag tccggcgtcg cgggcggccg ccacgtactt
    16561 gaggacgacc ccggactgct tgacgccgag cgccgccgtc ggctcgtcga ggacgaggac
    16621 cttggcgccg aagtacaccg cgcgggcgat ggccacgcac tggcgctcgc cacccgacag
    16681 ggtgccgatc ggctggtcga cgtcccgcag gtcgatgccc atgcgcagca gctcggcgcg
    16741 ggtcgtctcg cgcatgaggt cgacgtcgag gcgcttgaag gggccggcgc ccttggtggg
    16801 ctcggagccg aggaagaagt tccgccagac cggcatgagg gggacgacgg ccaggtcctg
    16861 gtagacggtg gcgatgcccc ggtccagggc ctcgcgcggg gaagagaggg aggtctcctc
    16921 gccctcgatg cggaaggtgc cgccgtcgtg ggcgtgcagg cctgcgatga tcttgatgag
    16981 ggtggacttg ccggcgccgt tgtcgcccag gacgcaggtg atctcgcccg cgtgcacttc
    17041 gagggagacc ccttcgaggg cgcggatgtt gccgtagtac ttgctgacgt cggccagctc
    17101 gacgagtgcg gtcacttggt cgcctccgcg cgcttgcgga cccaggcgtt gagcagggtc
    17161 gcgagaagga gcatcgctcc gaggaagaac ttgaaccagt cagggttcca ctcggcgtac
    17221 acgatgccct tgctggtcat gccgaagatg aacgcgccga ccgccgagcc gatggcggag
    17281 ccgtatccgc cggtgatcag gcagccgccg atcacggccg cgatgatgta gatcagctcg
    17341 ttgccgacgc cctcgccgga ctggacgacg tcgaacgaga acagcaggtg ctgtccggac
    17401 acccaggcgc agaaggccac gcccaggtag aggccgatct tcgtcgtacg gaccgggacg
    17461 ccgacggcgc gggcggcgtc ggcgccgccg cccaccgcga agatccagtt gccgaagcgg
    17521 gtgcgcagca ggatccaggt ggccagcgcc accaggccga accaccacag gatggtgacc
    17581 ttgatgtcga tgccgccgag ggagaactgg gaggcgaaca gcgcccgggc ggagccgaag
    17641 ccctccatgt ccgcgatggt cctggtcgac acggtgccgc tgatcagctt ggtcaggccg
    17701 aggttcaggc cggtcagcat caggaacgta ccgagcgtga tgatgaagct cggcagtttg
    17761 gtccgggtga gcatgacgcc gttgaagacg ccgatggcga gggtgaccag gagggagacg
    17821 aggacgccga cccagatgtt cgcggtcatc tggtagctga acatcgagga gaccagcgcg
    17881 gagctggtca ccagcacacc ggccgacagg tcgaactcgc cgccgatcat cagcagcgcg
    17941 acggggacgg ccatgatgcc gatcgtcgag gcggcgtaga ggaccgtgcc gaagctggac
    18001 gccctcagga agctgtcggc gacgatcgag aagaagagga agacggcgac ggctccgacg
    18061 acggagccga gctcggggcg gccgaggagc ccccgcagcg gcgaggtgcg cagcaggcgc
    18121 tcgtcgacgg gtgaaccgtc cttcacgggt ggtgcggtcg tggtcatcgg gttcctcgct
    18181 ccgtgaattc cgccagcttg gcggcgtcct tctcggtgat gatctgcggc ccggtgagca
    18241 caggcctgcc gccgccgagc acgtcggcgt tgtagcggtg cagccacagc aggtcgacgg
    18301 cctcgtaccc ctggaggtag ggctgctggt cgacggcgaa gccgagctgc ctgctcttca
    18361 ggccggcggc caccttggcg ttgaggtcga aggtgtcgat ctcggcgtcg gacccggcgg
    18421 tcctcttcgc ctggacggcg gcgtcggcga acggcgcgcc gagggtgacg acggcgtcga
    18481 tggaccggtc ggtctggagt ttcgcctcga tggaggcctg tacgtcgggc atgttggtgc
    18541 cgtcgacgta caggttctgc acgtcgccgt cgaaggtctt cttcaccccg gcgcaacgct
    18601 gctcgtggcc gacgttgccc tgctcgtgca ggacgcacag ggccttcttg cggccgcgct
    18661 cgtcgagctc gtcgccgacc gcctcgcccg cgatgttctc gtcctgcccg atgtgggtga
    18721 gggcaccgta ggccttggac tgctccgagc cggagttgac ggtgatcacc gggatgccgg
    18781 ccttgacggc cctggcgacg gacgccttca tggcgtcggg cttggcgagg gtgacgatca
    18841 ggccgtcgac cttcttgtcg atgtaggagt cgacgagctg ggcctgctgc tggccctcgt
    18901 cgctgtgggc gtagaggaag gtgatgttgt ccttgacggc ggcctgcttg gcgccgttct
    18961 ggacgatgtc ccagaaggtg tcgccgtcgc cggagtgggt gaccatggcg atggtccacc
    19021 tgggggtgtt cacggctgcc cggccctcgg cggcggccgc cttgcgggcg tcctcggcgc
    19081 gcttgccgcc cgtggcgctg catcccgcgg ccgctcccgc gagggacact ccgagcaccg
    19141 tcgccagtac cgcgcggagc gcgcgtaccc ctgtccgaac ccttgccacg acgccgtgcc
    19201 cttcttgccg ctctgctcgc tgtgcctgct ctgctcgctg taccggccaa gtatcggtca
    19261 tggtgatgtg cccggatttc atcgggtacc gcgggcggtc agttcctcca gcaccggtac
    19321 gtccttctcg gtgacgaggg ccgggccggt gagaaccggc ttgccgccgc cgatgatgtt
    19381 gaggttgtcc ttgtggagcc agagcgagtc gacggcgagg tagccctgga ggtagggctg
    19441 ctggtcgacg gcgaagccga tctgctgggc cttgagctgg gcgacgacgg ccgcgttgag
    19501 gtcgaaggtg ttgatctcgg cgccggagcc ggcgctctgc ctggccttga cggaggcggc
    19561 ggcgaacggg gcgccgaggg tgacgacggc gtcgatgtcc ttggcgctct ggagcttggc
    19621 ctcgatggag gaggtcgcgg cgggcatgtt ggtgccctcg acgttgaggt tctccacgat
    19681 gcccttgaag gtcttcctga cgccggcgca gcgctcttcg agggacacgt ttccctgctc
    19741 gtggatgacg cagagggcct tcttcctgcc gcgtgcggtg agctcgtcgc cgacggcctc
    19801 gcccgccacg gcctcgtcct ggccgatgtg gccgagcgcg ccgaaggcct tggagtgctg
    19861 cccgccggag ttgatggtga cgacggggat gccggcggcg acggccttgg cgacggatgc
    19921 cttgaccgct tcgggcttgg cgagggtgac gatcaggccg tcgaccttct tcgtgacgta
    19981 ggagtcgatg agcgcggcct gttccttgcc ctccttgttg gcggcgtaga ggaactcgac
    20041 gttgtccttg gcggcggcgg ccttggcgcc gctctggacg atgtcccaga aggtgtcgcc
    20101 ctcgccggag tgggtgacca tcgcgacggt catgcgtggg gtggcggcgg gtttgccgcc
    20161 gccggaggtg tgggtggcct tgttctcgga gtccttgccg cccgagctgc tgcatccggc
    20221 ggcggtgacg gtgagtgcga ctgcggtcag cagggctgcc gctgccgtgc gggtggtacg
    20281 catcgtgggt ccgccttgtc ttccccggcg ccgcccgatt gcggctgggt gagtttctac
    20341 gggggcgggg cggacccgtc aatactttgt ccgaacattc ttacgcgatg acgtacggac
    20401 gggcttacgg ccgcaccagg agctggaact cgaacgcgta ccgcgacgcc cggtagatgt
    20461 gcgagccgaa ctccaccgcc cggccggtgt cgtcgaaggt ggtccgctcc atcgtcagca
    20521 gcggcgcgcc cttctcctcg gtgagcagct ccgcctccag gctcgtcgcg gcccgcgccc
    20581 cgaccttctg gcgggcgctg tgcagcgtga tgcccgcgcc gcgcatcatc cggtacaggc
    20641 cggtcccctc cagcagctcg gtgtcgaggt cgagcaggcc gagcggcagg tggttgcgca
    20701 gccgcgccat cggctcgtcg tgcgcgaagc gcagccgctc cacgtaccgg acgtcggtgc
    20761 cctcgggtac gccgagggcg gcggcgacct cggcggtggc ggggtcgatc cggttggtca
    20821 ggacgatggt ggcggggcgc tggccggccg cctccaggtc gtcgtacagg ctgctgagtt
    20881 ccagcgggcg cttgacctgg ctgtgcacga cctgggttcc gacgccccgg cggcgcacca
    20941 gcaggccctt ctcgacgagg gcctggatgg cctggcggac ggtcggccgg gacaggccga
    21001 gccggcccgc caggtcgatc tcgttgccga ggaggctgcc gggggtgagt gtcccgcgct
    21061 cgatggccgc ctccagctgc tgggagagct ggaagtagag cgggaccggg ctggtgcggt
    21121 ccacgctcag cggcagtcgc acgacgggac cggtctcttc tctggctgct cgggtctgct
    21181 tgggcacggc ccgagcctat ccacaggaaa tgatgacggg aagttgtgaa gtcatgttgt
    21241 caggacaaaa gcttgacacg atgacgataa cggcaccacc ttgggggcca tgcgcatcgg
    21301 actcatcgga acgggacgta tcggggcctt ccacgcgggc gtgctcagcc gccaccggga
    21361 agtgggagcc ctcgtggtcg ccgacgccga ccccggccgg gcggcccagg tcgccgacct
    21421 caccggcgcc acggccgcgc cgaccgtcga cgacgtcttc gcccggggcg tggacgcggt
    21481 ggtcatcgcc tcggcgaccg ccgcccacgc cgaactcatc ggccgcgccg cccgcgccgg
    21541 cctgcccacc ttctgcgaga aacccatcgc cctcgacctg cccggcacac tcggcgcgct
    21601 ccgcgaggtc gaggcggccg gcacccagct ccagctcggc ttcatgcgcc gcttcgacgc
    21661 cggctaccgg gccgcccgcg acgccgtcca ctccgggcgc atcggccggc tgcacaccgt
    21721 acgggccatc acctccgacc cggcgccgcc gcccgccgcg tacctcccgc tctccggcgg
    21781 cctctaccgc gactgcctgg tccacgactt cgacatcctc cgatgggtca ccggccgcga
    21841 ggtcaccgag gtgtacgcga ccggctcgga cggcggcccg gccatgttcc gcgaggccgg
    21901 cgacgtcgac acggcggccg cgctcctcac cctcgacgac ggcaccctcg ccacggcgac
    21961 ggccacccgc tgcaacggcg ccggctacga cgtacggatg gagctggcgg gcgagcgcga
    22021 ccagatcgcg gtgggcctcg acgaccgcac gcccctcacc tccaccgaac cgctcggccc
    22081 gcccgccgcc gacaagccct ggccgggctt cctggagcgg ttcgcgcccg cctacgaagc
    22141 cgagctggac gccttcgtcc acctcgcgcg cggcgagctg gccaacccct gcgacggcca
    22201 cgaggccctc caggcgctgc gcgtcgccga ggcgtgcgag ctgtcgcgcc gcgagcggcg
    22261 cccggtgcgg ctggaggagg tgccgtcagc cctctgacgg cgaggacgac gacaggaccg
    22321 tgccctgggc caccgcgcac agggtctcgg ccccgtctcc gtcctggtcc cgcgtcagca
    22381 ggtcgcagcg caccaccgcc tgccgccggc ccgcgtggac cacggaggca cgggccagga
    22441 gcgtgcggcc ggtggcgggg cggacgtact ggatggagaa cccggccgtc agcacggcgg
    22501 gtcccagggc gctgcccgcc gcgaaggtga tggcgttgtc ggcggcgtac gacaggacgc
    22561 cgccgtgcag gaagccgttc t
//
