LOCUS       NZ_LIYH01000002        25219 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000002
VERSION     NZ_LIYH01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1373731)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373731)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 24058
            Orig. end                         :: 49277
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25219
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25219
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25219
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15219]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15219
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1719..3461
                     /gene="lysS"
                     /locus_tag="AMK26_RS06820"
                     /old_locus_tag="AMK26_06730"
     CDS             1719..3461
                     /EC_number="6.1.1.6"
                     /GO_component="GO:0017101 - aminoacyl-tRNA synthetase
                     multienzyme complex [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lysS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948672.1"
                     /locus_tag="AMK26_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06730"
                     /product="lysine--tRNA ligase"
                     /protein_id="WP_073753198.1"
                     /transl_table=11
                     /translation="MPIVAQSSTETDWVSRFADEVIAESERRAPGKPVVVASGLSPSGP
                     IHLGNLREVMTPHLVADEIRRRGYEVRHLISWDDYDRYRKVPLGIPGVDGSWEEHIGKP
                     LTSVPAPVGSAYPNWAEHFKAGMIESLAELGVEYDGISQTEQYTSGAYREQILHAMRHR
                     GTIDAILDRYRTKDKATGKPKKQQQKPVDEAELVAEEGSGAASEDDGSGGAGGYFPYKP
                     YCGQCGKDLTTVTSYDDESTELAYSCACGFSETVKLSEFNRGKLVWKVDWPMRWAYEGV
                     VFEPSGVDHSSPGSSFVVGGQIVREVFDGVQPIGPMYAFVGISGMAKMSSSKGGVPTPA
                     DALQIMEAPLLRWLYARRKPNQAFKIAFDQEIQRLYDEWDKLEAKVADGSVLPADAAAH
                     SRAVRTAAGELPRTPRPLPYRTLASVVDITAGHDEQTLRILSELDPANPLASLDEARPR
                     LDRAQNWISTQVPAEQRTIVRSEPDTELLGSLDEEGRESLRLLLEGLDSHWSLDGLTTL
                     VYGVPKVMAGLDPEAKPTPELKVAQRTFFALLYRLLVSRDTGPRLPTLLLAVGADRVRK
                     LLGA"
     gene            3596..3799
                     /locus_tag="AMK26_RS06825"
                     /old_locus_tag="AMK26_06735"
     CDS             3596..3799
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888515.1"
                     /locus_tag="AMK26_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06735"
                     /product="hypothetical protein"
                     /protein_id="WP_073753200.1"
                     /transl_table=11
                     /translation="MKEIVAVIGWVTGVQGVLGVAGRTFGDGPWGLLHKWWEIPTAGYA
                     VIAVLGAVLAVYGETAKVRARR"
     gene            complement(3814..5139)
                     /locus_tag="AMK26_RS06830"
                     /old_locus_tag="AMK26_06740"
     CDS             complement(3814..5139)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888516.1"
                     /locus_tag="AMK26_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06740"
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_073753202.1"
                     /transl_table=11
                     /translation="MAAMQLTRTHRILIGVVITGAVIIAGIGFAGSYAAVRELAEKKGF
                     GDFSIVFPIGIDAGICVLLALDLLLTWLRIPFPLLRQTAWLLTAATIAFNGAASWPDPL
                     GVGMHAVIPVLFVVAVEAARHAIGRIADITADKHMEGVRLTRWLLSPVPTFRLWRRMKL
                     WELRSYEQVIKLEQDRLIYQARLQARFGRAWRRKAPVEALMPLRLAKYGVPLAETAPAG
                     LAAAGIEPVLLPPNPVLLEKAVPELELPQGEAHQHGTPDDRDQPVAHAHPQPHPQPRPQ
                     PEPQPGNRPESEPQPEPQPDGQLPGNHVSPWFAAPQLPQDAYERAYAPTYVEGLEPTPV
                     RVPPGPDGHDGREEPMPAGTSGPAETAELADPDAEEFSRLAYPVFKQYVDENNDWPSVD
                     VIDIHLADGYGIRHPLSAVLLRRLLPEFKNRYQAELAAEHIA"
     misc_feature    5224..5239
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            complement(5269..5994)
                     /locus_tag="AMK26_RS06835"
                     /old_locus_tag="AMK26_06745"
     CDS             complement(5269..5994)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005313969.1"
                     /locus_tag="AMK26_RS06835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06745"
                     /product="DUF3558 domain-containing protein"
                     /protein_id="WP_073753204.1"
                     /transl_table=11
                     /translation="MYRSAPRLTRILACAAVPVMLVVAGCSSDSDSKSDADAQSPSTAS
                     SPQAAVKPKPTVAPAKYTQLPEACKAITGKTIEDLVPEVKNEKGTPGKSSDTASRGSCA
                     WNGLDDNGIKGSQYRWLDISLLRYDSDPSLGSAEQRAQENYTKEVAKVKATEGATSVKT
                     SPAAGVGNEATAISYGLKKTDEDFKYAAIVTRTENVLITVSYNGAGYAGAKTPTPSDLM
                     EDAVKASKEAVAAVAAANK"
     gene            complement(6113..6946)
                     /locus_tag="AMK26_RS06840"
                     /old_locus_tag="AMK26_06750"
     CDS             complement(6113..6946)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948675.1"
                     /locus_tag="AMK26_RS06840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06750"
                     /product="hypothetical protein"
                     /protein_id="WP_073753206.1"
                     /transl_table=11
                     /translation="MQRRAYVPGVAALLAALTVGVTGLAGCSAGSGPDGATTDSKAGGP
                     ADTAVQPGKYRTLLEPCGSVQRSTLKDLLPGAAQLPEEQRERVYRGTPSATYDTDRRAG
                     CSWKTDGPDASHQLTLDFERVVSYDPTVSDDDRAQQVYAEKEAAAGLPSQAPAPAAGTA
                     QQAPPTTGPTASPAAKATTPTADPTPTGSAGTPEGLEPRVLAGLADAAFLDDVLTRAGS
                     TAQHRTVSVVFRTSNVIVTIRYGEQPARVTEVPDSKELQEKAQGLARNLAERFEE"
     gene            7133..8326
                     /locus_tag="AMK26_RS06845"
                     /old_locus_tag="AMK26_06755"
     CDS             7133..8326
                     /EC_number="6.5.1.8"
                     /GO_function="GO:0008452 - RNA ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577624.1"
                     /locus_tag="AMK26_RS06845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06755"
                     /product="RtcB family protein"
                     /protein_id="WP_073753208.1"
                     /transl_table=11
                     /translation="MSYVEVPGAKVPIRMWTDPSTVEDGAMRQLRNTATLPWIKGLAVM
                     PDVHYGKGATVGSVIAMHGAVCPAAVGVDIGCGMSAVKTSLTANDLPGDLSRLRSKIEQ
                     AIPVGRGMHDEMVDPRRLHGFPGAGWDDFWARFDGVAESVKFRRDRAVKQMGSLGSGNH
                     FVEFCLDESGSVWLMLHSGSRNIGKELAEHHIGEARKLPHNQGLVDRDLAVFIADTPQM
                     AAYRNDLFWAQEYAKYNRAIMMALFQDVVRKEFKKARVTFDRVISCHHNYVAEERYDGM
                     DLLVTRKGAIRAGSVDFGIIPGSMGTGSYIVKGLGNEASFNSASHGAGRKMSRSAAKRR
                     FSTRDLEEQTRGVECRKDSGVVDEIPGAYKPIEKVIDQQRDLVEVVAKLKQVVCVKG"
     gene            complement(8359..9153)
                     /locus_tag="AMK26_RS06850"
                     /old_locus_tag="AMK26_06760"
     CDS             complement(8359..9153)
                     /NRPS_PKS="Domain: PKS_KR (17-178). E-value: 6e-14. Score:
                     44.3. Matches aSDomain:
                     nrpspksdomains_AMK26_RS06850_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240968.1"
                     /locus_tag="AMK26_RS06850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06760"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_073753210.1"
                     /sec_met_domain="adh_short (E-value: 8.2e-36, bitscore:
                     119.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAATPAGSTDSPGVPVAVVTGASSGIGAATARRLAGAGHHVVL
                     TARRKDRIEALAAELTAAGHRATAYALDVTDRPAVDAFAAGLERCDVLVNNAGGALGAD
                     PVATGDPADWRRMYEVNVIGTLHMTQALLPALTASGAGTVVVVSSTAAHATYEGGAGYV
                     AAKNGARVLAETLRLEILGTPVRVIEIAPGLVKTDEFATTRFRGDTEKAAKVYAGVPDP
                     LSADDVADTITWAVTRPAHVNIDLLVVRPRAQASNTKVHREL"
     aSDomain        complement(8620..9102)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS06850_PKS_KR.1"
                     /evalue="6.00E-14"
                     /label="AMK26_RS06850_PKS_KR.1"
                     /locus_tag="AMK26_RS06850"
                     /protein_end="178"
                     /protein_start="17"
                     /score="44.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGASSGIGAATARRLAGAGHHVVLTARRKDRIEALAAELTA
                     AGHRATAYALDVTDRPAVDAFAAGLERCDVLVNNAGGALGADPVATGDPADWRRMYEVN
                     VIGTLHMTQALLPALTASGAGTVVVVSSTAAHATYEGGAGYVAAKNGARVLAETLRL"
     CDS_motif       complement(8638..8742)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK26_RS06850_0002"
                     /evalue="2.10E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK26_RS06850"
                     /protein_end="172"
                     /protein_start="137"
                     /score="1.2"
                     /tool="antismash"
                     /translation="ASGAGTVVVVSSTAAHATYEGGAGYVAAKNGARVL"
     CDS_motif       complement(9007..9096)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK26_RS06850_0001"
                     /evalue="4.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK26_RS06850"
                     /protein_end="49"
                     /protein_start="19"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VVTGASSGIGAATARRLAGAGHHVVLTARR"
     gene            9276..9776
                     /locus_tag="AMK26_RS06855"
                     /old_locus_tag="AMK26_06765"
     CDS             9276..9776
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888521.1"
                     /locus_tag="AMK26_RS06855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06765"
                     /product="hypothetical protein"
                     /protein_id="WP_073753212.1"
                     /transl_table=11
                     /translation="MVAMRRALLVMSVAVATVAGVSVGVGGAAETAGDGMAGPEADVAH
                     HGHVTLWDGRLDVVLLSENRGPSGLDDTTVRLAFSVPLAAGHALPAGCVWGGEREVLCS
                     TGPLRVDGTRHETALTLRTAGVAPQELTARVATAWNGGAVDRNPADNDHRVLVLATGDP
                     YVF"
     gene            10001..11059
                     /locus_tag="AMK26_RS06860"
                     /old_locus_tag="AMK26_06770"
     CDS             10001..11059
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324124.1"
                     /locus_tag="AMK26_RS06860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06770"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_073753214.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.7e-65, bitscore:
                     216.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGLTAIGAQPATSAYALFDWARELVTPALRDAVRAMPPPECRIV
                     GYHRGWHEADGGPPAAPVGERGGKAVRPALAFLSARAVGGAAEAAVPAAVVVELVHDFS
                     LLHDDVIDGDPLRRHRPAAWTVYGTPAAVLTGDALLVNAVRTLAESSAPRTEPALRELI
                     TALVDLMRGQSQDVAFEKATMVAPAEYLSMAEGKTGALMGCACALGGVLAGASEDRVSG
                     LRDFGRCLGVAFQCVDDLLGIWGSSARSGKPVGADLAARKKSLPVVVALADEGPVGRRL
                     ADLYAGSAPLPEADVALAARLIEEAGGRERTELEAKRQVAAAMRALARAEPAPEIYRQL
                     HDIAVLMTGRDR"
     misc_feature    11120..11134
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.35"
                     /tool="antismash"
     misc_feature    11173..11188
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    complement(11176..11189)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.83"
                     /tool="antismash"
     gene            11219..12073
                     /locus_tag="AMK26_RS06865"
                     /old_locus_tag="AMK26_06775"
     CDS             11219..12073
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063788.1"
                     /locus_tag="AMK26_RS06865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06775"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_079277482.1"
                     /transl_table=11
                     /translation="MRSREAVGPPAISVYGLHVARGTHTLLQDISFTVPRGTIVGLLGP
                     SGCGKTTLLRSVVGIQPCTSGHVQVLGCPAGAPALSSRVGYVTQAPSVYPDLTVLENLR
                     YFSAALGLRGWRRENAVVRVVKEVDLAEYADKPVARLSGGQYSRVSLAVALLGTPDLLV
                     MDEPTVGLDPLVRRELWAVFKRLAEEGTTLLVSSHVMDEADRCDRLLLMRAGRLLASAG
                     RNDLLLHTGCDSVEEAFMHLVTSAEAAETGRRRPGAEPVREPLITDVLHDPDRPYFASE
                     SPW"
     gene            12169..12861
                     /locus_tag="AMK26_RS06870"
                     /old_locus_tag="AMK26_06780"
     CDS             12169..12861
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010277327.1"
                     /locus_tag="AMK26_RS06870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06780"
                     /product="ABC transporter permease"
                     /protein_id="WP_241837820.1"
                     /transl_table=11
                     /translation="MLQQISRDRGSAALMLVIPCMLMVLLKLMFHDAEESFERVGPQVF
                     GIFPVIVMYLVASVSTLRERTSGTAERLLTLPVQRLDIVLGYSLAFAFLAMLQAVLSTL
                     LAIGPLGLDIKGPAYLLMVIAMLGALLGLALGLLVSAFARNEFQAVQFLPAGVLPQFLV
                     CGLFVPREEMHGSLDALAQVMPMTYAVQAATEAARHDGVTGVFVRDALLILLCVIGVLV
                     ASAATLKR"
     gene            complement(12934..13185)
                     /locus_tag="AMK26_RS06875"
                     /old_locus_tag="AMK26_06785"
     CDS             complement(12934..13185)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS06875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_06785"
                     /product="hypothetical protein"
                     /protein_id="WP_073753216.1"
                     /transl_table=11
                     /translation="MSFFRRAAAISVVAITLAAGGAAPSAFAAPSSPAVDIDGPGGRRG
                     HDRPMNFGPFEVPRNGHVTAGFAWGTSNRDDRDDYDRY"
     misc_feature    13332..13346
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    complement(13570..13579)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            13776..14129
                     /locus_tag="AMK26_RS36900"
     CDS             13776..14129
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="AMK26_RS36900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CAP domain-containing protein"
                     /protein_id="WP_158071104.1"
                     /transl_table=11
                     /translation="MNQERSRAGCPAVRQHSAVTKAAQGHSAYMARTGALSHTGHKGSD
                     PGSRLTAAGYRWSRAGENIVAGPEDAAAAVRSWMNSPEHRESVLTCQFRHAGVGVGRGP
                     DGPWWTLLFAAPR"
     misc_feature    complement(13794..13808)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            complement(14143..15219)
                     /locus_tag="AMK26_RS06885"
                     /old_locus_tag="AMK26_06795"
     CDS             complement(14143..15219)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="AMK26_RS06885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06795"
                     /product="hypothetical protein"
                     /protein_id="WP_143608471.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-72, bitscore: 242.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLSLTEADLPLIHCPWDSAVHPHARQVEKQAEEWIRDSGMCATD
                     DECAWVVATHSTDFFARFAPVADDDRLLATSLWVYWGFGIDDARCDNGPLSARPALFNA
                     LAGRVQRAAEAPSATDGGERYIPALQDILARFRSFGTAAQVRRFTHAQRAWLSGVCWQV
                     GNQASGRMPELDEFLAMRLLSSGGEPTFAMLELATGLEVPDNELHRPAVRALTEMAILV
                     AALDNDRHSLRKELSRGHTDQNIYSVLMCHESMSLPEAVEAATRLRDRVLVRFTRLHDR
                     VRPHAGAALANYLQGLRHGIRGNAEWGLRVPRYLSLGRVPDAMEETPLEWAEEPADSRP
                     TPPPGAPTIAWWWDEDLA"
     misc_feature    15303..15316
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.3"
                     /tool="antismash"
     gene            complement(15410..16831)
                     /locus_tag="AMK26_RS06890"
                     /old_locus_tag="AMK26_06800"
     CDS             complement(15410..16831)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005313938.1"
                     /locus_tag="AMK26_RS06890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06800"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_073753220.1"
                     /transl_table=11
                     /translation="MNGTAGTEFDVIVVGAGPTGLLLAGDLAAAGVNVTVVERRPHETS
                     NMTRAFGVHARTLELLDARDLADELVHKGTSVTGLRFFRKLSLDLSRLPSRFPFLLITP
                     QYEVERLLERRAVAAGVDFRYGTELRALHQDDGTVTAEVTGADGTPGTLRARYLVGTDG
                     HRSAVRRDLGLPFPGSSVIRSMVLADVRLAEEPDELLTVNGVGDTFAFIAPFGDGWYRV
                     MGWNRQRQVPDSEPVGLDEVREIARLALGSDFGMHDARWISRFHSDERQVPAYRSGRVF
                     LAGDAAHIHSPAGGQGMNTGLQDAANLSWKLASVLRGEAPDPEALLDSYHAERHPVGTM
                     VLRSSGALVRLAMAHNPLERMARALGAGLLNAVRPAAAKAMGMVSGIGISYRAERGAHR
                     LVGRRAPDLTLTEGRLYELLRKGRFVLVAPQGAAPQAPRIPVPGRVIRASWANSTRQDT
                     VLVRPDGYIAWAAKA"
     misc_feature    complement(16886..16901)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            16948..17508
                     /locus_tag="AMK26_RS06895"
                     /old_locus_tag="AMK26_06805"
     CDS             16948..17508
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240971.1"
                     /locus_tag="AMK26_RS06895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06805"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_073753222.1"
                     /transl_table=11
                     /translation="MTTPRRSDTTRAAILEAARERFAADGYERATIRAIARDAGIDPSM
                     VMRYYGNKEGLFAAASEIDLRLPPLGALPAQHIGAVLVTHFLDRWEQDDVLTGVLRVGV
                     TNAAGAERMRAVFKAQLGPIAAGVCPDPADAPRRAALAASQILGMALARYVLRLPPAVD
                     MSREEVIAWLGPTIQRYLTADRP"
     gene            complement(17540..18274)
                     /locus_tag="AMK26_RS06900"
                     /old_locus_tag="AMK26_06810"
     CDS             complement(17540..18274)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472685.1"
                     /locus_tag="AMK26_RS06900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06810"
                     /product="Mut7-C RNAse domain-containing protein"
                     /protein_id="WP_073754694.1"
                     /transl_table=11
                     /translation="MNGPEIHISFAPGLGLFVAAPRRAGRSVVVTDGVSTLGHVVESLG
                     VPLTEAGLLLVDGRPVTPAHIPAAGEHVQVLGVERPQPVPGAPLRFLLDVHLGTLARRL
                     RLLGVDAAYESEDIGDAALATWSAKERRVMLSRDRGLLRRRELWAGAYVYSDRPEDQLR
                     DVLERFAPPLAPWTRCTACNGPLADADKDAVRDQLEQGTQRTYDVFAKCTECGRVYWRG
                     AHHSRLEAIVEDALREFGDAAA"
     gene            complement(18420..18959)
                     /locus_tag="AMK26_RS06905"
                     /old_locus_tag="AMK26_06815"
     CDS             complement(18420..18959)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524993.1"
                     /locus_tag="AMK26_RS06905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06815"
                     /product="GNAT family protein"
                     /protein_id="WP_073753224.1"
                     /transl_table=11
                     /translation="MGSGASPVRLEAWSERDFDLLRAVNAPELMAHLGGPETAEQLVKR
                     HQRYVDLSADRSGAGRMFRIVLEPEGVPVGVIGFWEQTWDGTRVYETGWTVLGGFQGRG
                     VATAATVAVADRARAARKHRYLHAFPSVDNGPSNAVCRKAGFELLGERDFEYPPGHLLR
                     SNNWRLDLEAGDPGSR"
     gene            complement(18964..19551)
                     /locus_tag="AMK26_RS06910"
                     /old_locus_tag="AMK26_06820"
     CDS             complement(18964..19551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326956.1"
                     /locus_tag="AMK26_RS06910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06820"
                     /product="hypothetical protein"
                     /protein_id="WP_073753226.1"
                     /transl_table=11
                     /translation="MHRGGGLGEGTDDLGPEPARRGKHRREQDKASQDRASLGPMGGGS
                     GGGRGMGVTYKYFGAPNGATAARVPISMRPEELGGDELGMGGMFTKIKPETIAAMVLTG
                     IQGMPLHKVPPLELVVLHPDYAVVKLPMTVVDPLRGIGEESVGAAAFIWSTVPDRGGPR
                     DAFNVYQLLHEWQDFSVRLHEAGHQPYCLVWP"
     misc_feature    19567..19580
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.47"
                     /tool="antismash"
     misc_feature    complement(19569..19582)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.49"
                     /tool="antismash"
     gene            19855..21162
                     /gene="hemL"
                     /locus_tag="AMK26_RS06915"
                     /old_locus_tag="AMK26_06825"
     CDS             19855..21162
                     /EC_number="5.4.3.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (42-364). E-value: 6.4e-74.
                     Score: 240.9. Matches aSDomain:
                     nrpspksdomains_AMK26_RS06915_Aminotran_3.1"
                     /codon_start=1
                     /gene="hemL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609265.1"
                     /locus_tag="AMK26_RS06915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06825"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_073753227.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.6e-85, bitscore:
                     282.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYSYEAPVSQTLFDRASLVTPGGVNSPVRAFRAVGGTPRFMVSG
                     TGPYLNDADGREYVDLVCSWGPMILGHAHPEVIAAVQEAVARGTSFGTPGEGEVALAEE
                     IVARIEPVEQVRLVSSGTEATMSAIRLARGFTGRAKVIKFAGCYHGHVDALLAAAGSGV
                     ATFGLPDTPGVTGAQAGDTIVLPYNDLDAVRQAFAAHPGEIACVITEASPGNMGVVPPR
                     DGFNAGLKEICAENGALYISDEVMTGFRTSKAGWYGVDGVAPDLMTFGKVMGGGFPAAA
                     FGGRADVMAHLAPAGPVYQAGTLSGNPVATAAGLAQLRLLDDAAYEKVNAVSREIQGLV
                     TQALAKEGVAHRLQTASNMFSVFFTDAEVVNYDDAKKQEAFRFTAFFHSMLAQGVYLPP
                     SAFESWFVSTAHDERAVERIAAALPAAARAAAEATV"
     aSDomain        19981..20946
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS06915_Aminotran_3.1"
                     /evalue="6.40E-74"
                     /label="AMK26_RS06915_Aminotran_3.1"
                     /locus_tag="AMK26_RS06915"
                     /protein_end="364"
                     /protein_start="42"
                     /score="240.9"
                     /tool="antismash"
                     /translation="VSGTGPYLNDADGREYVDLVCSWGPMILGHAHPEVIAAVQEAVAR
                     GTSFGTPGEGEVALAEEIVARIEPVEQVRLVSSGTEATMSAIRLARGFTGRAKVIKFAG
                     CYHGHVDALLAAAGSGVATFGLPDTPGVTGAQAGDTIVLPYNDLDAVRQAFAAHPGEIA
                     CVITEASPGNMGVVPPRDGFNAGLKEICAENGALYISDEVMTGFRTSKAGWYGVDGVAP
                     DLMTFGKVMGGGFPAAAFGGRADVMAHLAPAGPVYQAGTLSGNPVATAAGLAQLRLLDD
                     AAYEKVNAVSREIQGLVTQALAKEGVAHRLQTASNMFSVFF"
     gene            21159..21842
                     /locus_tag="AMK26_RS06920"
                     /old_locus_tag="AMK26_06830"
     CDS             21159..21842
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019888537.1"
                     /locus_tag="AMK26_RS06920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06830"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_073753229.1"
                     /transl_table=11
                     /translation="MTGNDEITVVHLMRHGEVHNPDGILYGRRAGYHLSELGRQMADRV
                     AEHLAGRDVTYVAASPLERAQETAQPIAKSHGLDLATDERLIEAGNVFEGKTFGVGDGA
                     LRRPSNWRHLTNPFRPSWGEPYIDQVVRMMGALNAARDAARGHEAVCVSHQLPIWIVRS
                     FVERRRLWHDPRRRQCTLASLTTFTYQGDKIVSVGYSEPARDLVPPHLLAGAKPAKGKS
                     KAFGA"
     misc_feature    complement(22209..22222)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     gene            22784..24019
                     /locus_tag="AMK26_RS06925"
                     /old_locus_tag="AMK26_06835"
     CDS             22784..24019
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847628.1"
                     /locus_tag="AMK26_RS06925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06835"
                     /product="hypothetical protein"
                     /protein_id="WP_073753231.1"
                     /transl_table=11
                     /translation="MRGISRRGLLGAGVGAAAAMGVGGCGLGGGSDKPGSGPGEGGQKG
                     TAPGKVEGRLIGDGSTSDTGKQPNQPDRPVPLEPGQTPPQFVIFSWDGAGEVGNGLFPR
                     FLELAKNHDAGMTFFLSGLYLLPESKKTLYRPPNNRPGASDIGYLTDDHIKQTLTYVRQ
                     AWLDGHEIGTHFNGHFCAGSGSVEKWTPADWQSEIDQAVKFVTEWKTNSGWTDLDPLPF
                     DYRKELVGARTPCLLGQDNLLPTAKKLGWRYDASSPGGHQKWPVKRQGIWDLPLQQIPF
                     PGRSFEVLSMDYNMLANQSKNTTKGMPSRYPEWKKQATEAYLAGFTRAYESNRAPLYIG
                     NHFEQWNGGIYMDAVEEALKGMAGKKDVRLVSFKQFVDWLDVQDPGILDKLRTLEVGQS
                     PAGGWNTFLKPA"
     misc_feature    24072..24087
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            24087..24707
                     /locus_tag="AMK26_RS06930"
                     /old_locus_tag="AMK26_06840"
     CDS             24087..24707
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010472695.1"
                     /locus_tag="AMK26_RS06930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_06840"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_073753233.1"
                     /transl_table=11
                     /translation="MSLSRAPRGLLLTAGAALAAALTLAACSGDSNGTSGGGGNTNFVT
                     NTGGIDTVAKGERTAPNKLAGTTLDGKPLDVADLKGKVVVLNAWGSWCGPCRAEAKHFT
                     KVATDLKSEGVEFVGINTRDPNKQPALAFEKDFAVPYPSLYDPAGELILNGFPKGTLNP
                     QGIPSTVVLDRDGKIAARALMPLNETKLRKMIDPIAAEKASGN"
     misc_feature    complement(24833..24848)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
ORIGIN
        1 ccagcgtctc ggcgaactgg tccaggtgca ggcccagcgc gcgctcggcc ggggcgaggg
       61 cgatgtccgg gtgggcggcc ggcttggagt cgccggcctt gcggatgatc gacttgatac
      121 gggcgtacgc gtactggagg tagacggacg tgtcgccgtt gagcgacacc atctggtcca
      181 ggtcgaactt gtagtcccgg gacgcggacg tggacaggtc ggcgtacttg atcgcgccga
      241 tgccgacctg ggcggcgcgc tcggcgatct cgtcctcggt caggtcctgg gccttctcgc
      301 ggaccacggc cgccgcccgg tcgatcgcct cgtccagcag gtcgaccagc cggaccgtct
      361 cgccctcgcg ggtcttgaac ggcttgccgt ccttgccgag gaccgtgccg aaggcgagct
      421 ggacggcatg cacctggtcg cccagccagc ccgcgcggcg ggcggtttcg aagaccatct
      481 tgaagtgcag cgactggcgg gcgtccacca cgtacaccag ggtgtccgcg cccaggttct
      541 ggacgcggtc gcggatcgcg gacaggtcgg tggccgcgta gccgtagccg ccgttggact
      601 tcttgacgat cagggggacc gggttgccgt ccgggccctt gacgtcgtcg aagaagacgc
      661 acagggcgcc ctcggagcgg accgcgacgc cggactcctc cagcaggcgg cacgtctcgt
      721 cgagcatgtc gttgtagccg gactcgccga ccacgtccgg gtcgttgatc tccatgtcga
      781 gcttgttgaa gaccgagtag aagtagatct tcgactcgtc gacgaaccgc tgccacaggg
      841 cgagcgtctc ctcgtcgccc gactggaggg ccaccacgcg gtcgcgcgag cgcgccttga
      901 actcctcgtc ggagtcgaag tgcgcccggg ccgccttgta gagccggttg aggttggaca
      961 tcgcctcctc gccggagacg tccgcgtcct tgtggtccag ctcgtgcggg tgctcgatca
     1021 ggtactggat gagcatgccg aactgggtgc cccagtcgcc gatgtggtgg cggcggatca
     1081 ccttctcgcc cgcgaactcc atgatcttga ccatggcgtc gccgatgacg gcggagcgga
     1141 ggtgcccgac gtgcatctcc ttcgccacgt tcggctgggc gtagtcgatg accgtcgtgc
     1201 cggccttctc ggcgtacggg acgccgaggc gctcgtcggc ggcgcgggcg gcgagggtgt
     1261 cgaggatcgc cttgtcggtg agggtgatgt tgaggaagcc ggggccggag acctcgatgt
     1321 ccttgaggac gtcgttggcg ccgatggcct cgacgacctt ggtcgccagc tcgcgcggat
     1381 tgcccttgag cttcttcgcc agggccagga tgccgttggc ctggaagtcg gcccggtcgc
     1441 ttcgtcgcag cagcgggtcg gcggagccgg cctccggcag ggctgccgtc agggcgtccg
     1501 cgaggcgctg ccgcacggtc gaagcgaggg aagggaccga ggccatgagc ttccgttcct
     1561 gtcgtggtgg tgaatgccta ttccggttgt caagtgtccc atgggtccgc aagctctttg
     1621 tcggggcttt gcccggcctg tggacaacct cgggggacgt tgttccgtct gggagaatgt
     1681 cttacgccag ccttcgagaa tcccaaggaa tcaaggacgt gccgatcgtg gctcagagca
     1741 gcaccgagac cgactgggtc tcccgtttcg cggacgaggt catcgccgaa tcggagcgac
     1801 gtgcgcctgg gaaaccggtc gtcgtcgcct ccggcctgtc cccgtcgggc ccgatccacc
     1861 tgggcaacct ccgcgaggtc atgaccccgc acctggtcgc cgacgagatc cggcgccggg
     1921 ggtacgaggt ccgccacctg atctcctggg acgactacga ccggtaccgc aaggtgccgc
     1981 tcggcatccc gggcgtggac ggctcgtggg aggagcacat cggcaagccg ctgacctcgg
     2041 tccccgcccc ggtcggctcc gcgtacccga actgggcgga gcacttcaag gccgggatga
     2101 tcgagtcgct ggccgagctg ggcgtcgagt acgacggcat cagccagacc gagcagtaca
     2161 cctccggcgc gtaccgcgag cagatcctgc acgcgatgcg gcaccggggg acgatcgacg
     2221 cgatcctcga ccggtaccgg acgaaggaca aggcgaccgg caagccgaag aagcagcagc
     2281 agaagccggt cgacgaggcc gagctggtgg ccgaggaggg ctccggcgcg gcgagcgagg
     2341 acgacggctc cggcggcgcc gggggctact tcccgtacaa gccctactgc gggcagtgcg
     2401 gcaaggacct gaccaccgtc acctcctacg acgacgagtc gacggagctg gcctacagct
     2461 gcgcctgcgg cttctccgag acggtgaagc tgagcgagtt caaccggggc aagctggtct
     2521 ggaaggtcga ctggccgatg cgctgggcgt acgaaggggt cgtcttcgag ccgagcggtg
     2581 tcgaccattc gtcgcccggg tcgtcgttcg tcgtgggcgg gcagatcgtg cgcgaggtct
     2641 tcgacggcgt ccagccgatc ggccccatgt acgcgttcgt gggcatctcg ggcatggcga
     2701 agatgtcgtc gtccaagggc ggggtgccga ccccggccga cgcgctgcag atcatggagg
     2761 cgccgctgct gcgctggctg tacgcgcgcc gcaagcccaa ccaggccttc aagatcgcct
     2821 tcgaccagga gatccagcgg ctgtacgacg agtgggacaa gctggaggcc aaggtcgccg
     2881 acggcagcgt gctgccggcc gacgccgccg cccactcccg cgcggtgcgc acggcggccg
     2941 gtgagctgcc gcgtacgccg cgcccgctgc cgtaccgcac gctcgcctcg gtcgtggaca
     3001 tcaccgccgg gcacgacgag cagacgctgc gcatcctcag cgagctggac ccggccaacc
     3061 cgctggcctc gctcgacgag gcgcggccgc ggctggaccg cgcccagaac tggatctcca
     3121 cccaggtccc ggcggagcag cgcaccatcg tccgctccga gccggacacc gagctgctcg
     3181 gctcgctgga cgaggagggg cgcgagtcgc tgcggctgct gctggagggc ctggacagcc
     3241 actggtcgct ggacgggctg accacgctcg tctacggcgt gccgaaggtg atggccgggc
     3301 tcgacccgga ggccaagccg acgccggagc tgaaggtcgc ccagcgcacc ttcttcgccc
     3361 tgctgtaccg gctgctcgtc agccgggaca ccgggccgcg gctgcccacg ctgctgctgg
     3421 cggtgggcgc cgaccgggtg cgcaagctgc tcggcgcgta gcttccgcgg tttgtgcggg
     3481 gggagggctc tcacctgggg gtgagggccc tcctggcctt ctgcatcctt cggatgaccc
     3541 ggctttccgt ccggcgcagg acgttccggg gcgcggggca cgggaccgtg gagccatgaa
     3601 ggagatcgtg gcagtcatcg ggtgggtcac cggcgtccag ggcgtgctgg gcgtcgccgg
     3661 gcggaccttc ggggacgggc cctggggcct gctccacaaa tggtgggaga tccctacggc
     3721 cgggtacgcc gtgatcgcgg tgctcggcgc ggtcctcgcc gtgtacgggg agacggcgaa
     3781 ggtccgcgcc aggcgctgac ccgtggcggg cggttacgcg atgtgctcgg cggcgagctc
     3841 cgcctggtag cggttcttga actcgggcag caggcggcgc agcaggaccg cgctgagcgg
     3901 gtggcggatg ccgtagccgt cggcgaggtg gatgtcgatg acgtccacgc tcggccagtc
     3961 gttgttctcg tcgacgtact gcttgaacac cgggtacgcg aggcggctga actcctcggc
     4021 gtccgggtcg gcgagctcgg ccgtctcggc gggcccggag gtcccggcgg gcatcggctc
     4081 ctcgcggccg tcgtggccgt cggggcccgg cgggacgcgg accggggtgg gctccaggcc
     4141 ctcgacgtag gtgggggcgt aggcgcgctc gtaggcgtcc tggggcagct ggggggcggc
     4201 gaaccagggg ctgacgtggt tgccggggag ctggccgtcg ggctgcggct cgggctgcgg
     4261 ctcggactcg ggccggtttc cgggctgggg ttccggctgg ggccggggct gggggtgggg
     4321 ctgcgggtgg gcgtgggcta cgggctggtc ccggtcgtcg ggcgtcccgt gctggtgggc
     4381 ctcgccctgg ggcagctcca gctcgggcac cgccttctcc agcagcaccg ggttcggcgg
     4441 cagcagcacc ggctcgatgc ccgccgccgc caggcccgcc ggggccgtct cggcgagcgg
     4501 caccccgtac ttcgccagcc gcagcggcat cagcgcctcc accggggcct tgcggcgcca
     4561 cgcgcgcccg aagcgggcct ggaggcgcgc ctggtagatc agccggtcct gctccagctt
     4621 gatgacctgc tcgtacgagc gcagctccca cagcttcatc cggcgccaga gccggaaggt
     4681 gggtacgggc gagagcagcc accgggtgag gcgtacgccc tccatgtgct tgtcggccgt
     4741 gatgtcggcg atccggccga tggcgtgccg tgcggcctcc accgcgacca cgaacaggac
     4801 cgggatcacc gcgtgcatgc ccacgccgag cgggtcgggc caggacgccg cgccgttgaa
     4861 ggcgatcgtc gcggcggtca gcagccaggc cgtctggcgc agcagcggga aggggatgcg
     4921 cagccaggtc agcagcaggt cgagggccag cagcacacag ataccggcgt cgatgccgat
     4981 ggggaagacg atcgagaagt cgccgaagcc cttcttctcg gcgagctcgc gcaccgccgc
     5041 gtacgagccg gcgaaaccga ttccggcaat gatcaccgca ccggtgatga cgacgccgat
     5101 gagtattcgg tgcgtgcgtg tcagctgcat cgcggccacc cgcgatcccc tcccgttgac
     5161 gagtctggcg ggcaaagcct ggcacacgtg tgcggagccc ggtcctcggg ggacgtccgg
     5221 gctccgcatg tatgtgccag gtggttgccg cctgttgcgc ctgttgggct acttgttggc
     5281 cgccgcgacc gcggccaccg cctccttgga ggccttgacc gcgtcctcca tcaggtccga
     5341 cggggtcggg gtcttggcac cggcgtagcc cgcgccgttg taggagacgg tgatgagcac
     5401 gttctccgta cgggtcacga tcgccgcgta cttgaagtcc tcgtcggtct tcttcaagcc
     5461 gtagctgatg gccgtcgcct cattgccgac gcccgccgcg ggtgaggtct tgacgctggt
     5521 ggcgccctcg gtcgccttca ccttggcgac ctccttggtg tagttctcct gcgcgcgctg
     5581 ctcggcgctg ccgagcgacg ggtcggagtc gtaccggagg agggagatgt cgagccagcg
     5641 gtactgcgag cccttgatgc cgttgtcgtc caggccgttc caggcgcagc tgccgcggct
     5701 ggcggtgtcg ctggacttgc cgggcgtgcc cttctcgttc ttcacctccg gcaccaggtc
     5761 ctcgatggtc ttcccggtga tcgccttgca ggcctcgggg agctgcgtgt acttcgcggg
     5821 cgcgacggtc ggcttgggct tcacggcggc ctgcggcgag gaggcggtgg acggcgactg
     5881 cgcgtccgcg tcgctcttgc tgtcggagtc cgacgagcag ccggcgacga cgagcatcac
     5941 cggtacggct gcgcaggcga gtatgcgggt gagtcgcggg gctgatcggt acatggttcc
     6001 ttcagtcgct tgtcgtacgg tccggcggtc cggacacggt agcccgagtc ggtacgtccg
     6061 cgggggcgtc ccggcggcgt cacgggaccg gcccggggtg gctggggagt gactactcct
     6121 cgaaccgctc ggcgaggtta cgggccagac cctgggcctt ttcctgcagt tccttgctgt
     6181 ccggcacctc ggtgacgcgg gcgggctgct cgccgtaccg gatggtcacg atgacgttcg
     6241 atgtgcggaa caccacgctc acggtgcggt gctgggcggt cgaaccggcg cgggtgagga
     6301 cgtcgtcgag gaacgccgcg tcggcgaggc cggccagcac gcgcggttcc agcccctcgg
     6361 gggtgccggc gctcccggtg ggggtggggt cggcggtggg ggtggtcgcc ttcgcggcgg
     6421 ggctcgcggt ggggccggtt gtgggcgggg cctgctgggc cgtgccggcg gcgggcgcgg
     6481 gggcctggga gggcagcccg gcggcggctt ccttctccgc atagacctgc tgggcgcggt
     6541 cgtcgtcact gacggtgggg tcgtaggaca cgacacgctc gaagtcgagg gtcagctggt
     6601 gggaggcgtc cgggccgtcg gtcttccagc tgcagccggc gcggcggtcg gtgtcgtacg
     6661 tggcggaggg ggtgccgcgg tagacccgct cgcgctgttc ctcgggcagc tgggcggctc
     6721 cgggcaggag gtccttgagc gtggagcgct ggacggagcc gcagggctcc aggagcgtgc
     6781 ggtacttgcc gggctggact gcggtgtccg cggggccgcc cgccttggag tcggtggtgg
     6841 cgccgtcggg tccggagccg gcgctgcacc cggcgaggcc ggtgacgccg acggtgagcg
     6901 ccgcgaggag tgcggccaca ccgggtacgt acgcccttcg ctgcacggtc ccgggctcct
     6961 ttcgctctgg tgccggtcgg tacggccggc gggaaaacgg gttgccgccc gtcgccggtc
     7021 gatggacaca atgtgtatcg cacgcgccgc cgtcgatgcc ggtccgccgt ctctttcgcg
     7081 gaccttggag ccggtttttg cgctttcaga attttcgggg ggattgagaa ctatgtcgta
     7141 tgtagaggtg ccgggggcga aggtcccgat ccggatgtgg accgatcctt cgacggtgga
     7201 ggacggggcg atgcggcagt tgcgcaacac cgccaccctg ccgtggatca agggcctggc
     7261 cgtgatgccg gacgtgcact acggcaaggg cgcgacggtc gggtcggtga tcgcgatgca
     7321 cggggcggtc tgcccggcgg cggtcggggt ggacatcggc tgcggcatgt cggcggtgaa
     7381 gacgtcgctg acggcgaacg acctgcccgg tgacctgtcg cggctgcgct cgaagatcga
     7441 gcaggccatt ccggtcgggc gcggcatgca cgacgagatg gtcgatcccc gccggctgca
     7501 cggcttcccg ggcgcgggct gggacgactt ctgggcgcgg ttcgacgggg tggcggaatc
     7561 ggtcaaattc cgtcgggatc gagcagtgaa gcagatgggc tccctcggaa gcggaaacca
     7621 tttcgtcgag ttctgtctcg atgagtcggg atcggtctgg ctgatgctgc actccggctc
     7681 ccggaacatc ggcaaggagc tggccgagca ccacatcggc gaggcgcgga agctgccgca
     7741 caaccagggc ctggtcgacc gcgacctcgc tgtcttcatc gcggacaccc cacagatggc
     7801 ggcgtaccgg aacgatctgt tctgggcgca ggagtacgcc aagtacaacc gcgcgatcat
     7861 gatggcgctc ttccaggacg tggtccgcaa ggagttcaag aaggccaggg tcaccttcga
     7921 ccgggtcatc tcgtgccacc acaactacgt ggcggaggag cggtacgacg ggatggacct
     7981 gctggtcacc cggaagggcg cgatccgcgc gggctccgtc gacttcggga tcatcccggg
     8041 ctcgatgggc accggctcgt acatcgtgaa gggcctgggc aacgaggcgt cgttcaactc
     8101 ggcctcgcac ggcgcgggac ggaagatgag ccgctccgcc gccaagcggc gcttctcgac
     8161 gcgggacctg gaggagcaga cgcggggcgt ggagtgccgt aaggactccg gcgtcgtgga
     8221 cgagatcccg ggtgcgtaca agccgatcga gaaggtcatc gaccagcagc gcgacctggt
     8281 ggaggtcgtg gcgaagctga aacaggtggt gtgcgtgaag ggctgaggcg cgcccttcac
     8341 gtcacggccc cggtcccgtc acagctcgcg gtggaccttg gtgttggagg cctgggcacg
     8401 ggggcgcacc accagcaggt cgatgttgac gtgggcgggg cgggtgaccg cccaggtgat
     8461 ggtgtcggcg acgtcgtcgg cgctgagggg gtcggggacg cccgcgtaga ccttggccgc
     8521 cttctcggtg tcgccgcgga agcgggtcgt ggcgaactcg tcggtcttga ccaggccggg
     8581 ggcgatctcg atgacgcgga ccggggtgcc gaggatttcc aggcggaggg tctcggccag
     8641 gacgcgggcg ccgttcttgg cggcgacgta tccggcgccg ccctcgtagg tggcgtgggc
     8701 ggcggtggag gagacgacga ccaccgtgcc ggcgccgctc gcggtgaggg cgggcagcag
     8761 ggcctgggtc atgtggagcg tgccgatcac gttgacctcg tacatccggc gccagtcggc
     8821 ggggtcgccg gtggcgacgg gatccgcgcc gagggcgccg cccgcgttgt tgacgagcac
     8881 gtcgcagcgc tccaggccgg ccgcgaaggc gtcgacggcc gggcggtcgg tgacgtcgag
     8941 ggcgtacgcc gtggcccggt ggccggcggc ggtgagctcg gcggcgaggg cctcgatacg
     9001 gtccttgcgg cgggcggtga gcacgacgtg gtggcccgcc ccggcgagcc ggcgtgccgt
     9061 ggcggcgccg ataccgctgc tcgctccggt gacgacagcg acgggaacgc cgggggagtc
     9121 ggtggagccg gcgggggtgg cggcggcggt catggcggta ctcctcgcgc gggtgatcga
     9181 acggccggta cgcggccagc ataggcggcc gcgaagatcc ctccggagcg gcgggggaga
     9241 cacatggcgg ccggtcatat cggtatgttc cggacatggt tgcgatgcgc agggctctgc
     9301 tggtgatgtc cgtcgccgtg gcgacggtgg cgggtgtgag tgtgggcgtg ggtggggctg
     9361 ccgagacggc cggtgacggg atggccggac ccgaggcgga tgtggcgcac cacggccatg
     9421 tgacgctctg ggacgggcgg ctcgatgtcg tcctgctgag tgagaaccgc gggccgtcgg
     9481 ggctcgacga cacgaccgtg cggctggcct tctcggtccc gctcgccgcc ggtcacgccc
     9541 tgccggccgg ctgtgtgtgg ggcggcgagc gggaggtgct gtgctccacc gggccgttgc
     9601 gggtggacgg tacgcggcac gagacggcgc tgaccctgcg gacggccggc gtcgcgccgc
     9661 aggagctgac ggctcgggtg gccaccgcgt ggaacggcgg cgcggtggac cggaacccgg
     9721 ccgacaacga ccaccgggtg ctggtgctgg ccacggggga cccgtacgtc ttctgatgcc
     9781 cgccgggccg tgatcagagg gaccagccga ttaccgggag atctgcgttc cctgggccgc
     9841 tgaggtgatc tttctgtttc ccgggcgctg gaggcgacac ggacgccatc gctcggttag
     9901 ctggggccgt gccttacgaa cagtcagacc cccgccacgc agttcgagaa cgtgcccggc
     9961 cgagaggcat cccggcgccc ggtgccgtcg gaggcagcgc atgtcgggat tgaccgcgat
    10021 cggcgcgcag ccggccacgt ccgcgtacgc gctcttcgac tgggcccgcg agctcgtgac
    10081 ccccgctctg cgggacgccg tgcgggccat gcccccgccc gagtgccgca tcgtggggta
    10141 ccaccgcggc tggcacgagg cggacggcgg gccgccggcc gcgcccgtcg gcgagcgggg
    10201 cggcaaagcg gtgcggcccg cgctggcctt cctgtcggcc agggccgtcg ggggcgccgc
    10261 cgaggccgcc gtacccgcgg ccgtcgtggt ggagctggtc cacgacttct cgctgctgca
    10321 cgacgacgtg atcgacgggg atccgctgcg gcggcaccgt cccgccgcct ggacggtgta
    10381 cggcactccg gccgccgtgc tgaccggtga cgccctgctg gtgaacgccg tccggacgct
    10441 cgcggagtcg tccgcgcccc ggacggagcc cgccctgcgg gagctgatca ccgccctcgt
    10501 cgacctgatg cgggggcaga gccaggatgt ggcgttcgag aaggccacca tggtcgcgcc
    10561 cgccgagtac ctgtccatgg cggagggcaa gacgggggcg ctcatgggat gcgcctgcgc
    10621 gctgggcgga gtgctcgcgg gggcgtcgga ggaccgggtg tccgggctgc gtgacttcgg
    10681 ccggtgcctg ggcgtggcgt tccagtgcgt cgacgatctg ctgggcatct ggggttccag
    10741 cgcgcgcagc ggcaaacccg tcggtgccga tctcgcggcc cgcaagaaat cgctcccggt
    10801 ggtggtggcg ctggccgacg aggggccggt gggcagacgg ctggccgacc tctacgccgg
    10861 gtcggcgcca ttgccggagg ccgatgtcgc cctggcggcg cggctgatcg aggaggccgg
    10921 ggggcgggaa cggacagagc tggaggcgaa acgccaggtc gccgcggcga tgagggccct
    10981 ggcgcgggcc gagcccgccc cggagatcta ccggcaattg cacgacatcg cggtgctgat
    11041 gaccggtcgc gaccgctgat ttcaccggcc ggacggcggt gcgtcaacat gggaatgccc
    11101 tcttcgtaac cgagtgcgcc gacgttacgt tcctttttcc gggcagtcgc accgccgtgc
    11161 cgccacagcc atatctattg atgaaaacag tgggttcttg cagcagaatg atattcggat
    11221 gagaagccgg gaggcggtcg gtccgccggc catcagcgtg tacggcctcc atgtcgcgcg
    11281 cggaacccac actcttctgc aggacatcag tttcaccgtc ccccggggga cgattgtcgg
    11341 cctgctcgga ccgagtggct gcggaaagac gacgcttctg cggtccgtcg tcggaatcca
    11401 gccctgtacg tcgggacacg tgcaggtgct gggctgcccc gccggggcgc ccgccctgag
    11461 ctcccgggtg gggtacgtca cccaggcccc ctccgtctac cccgacctca ccgttctgga
    11521 gaacctccgg tacttctccg ccgccctggg gctgcggggc tggcggcggg agaacgcggt
    11581 ggtccgggtg gtgaaggagg tcgacctcgc cgagtacgcc gacaagccgg tcgcccggct
    11641 gtccggcggg cagtactccc gcgtctcgct ggccgtggcg ctgctgggca cccccgacct
    11701 gctcgtcatg gacgaaccca ccgtggggct ggacccgttg gtgcgccgcg agctgtgggc
    11761 ggtgttcaag cgcctcgcgg aggaaggaac gaccttgctg gtgtccagcc acgtcatgga
    11821 cgaagccgac cgctgcgacc ggctgctgct gatgcgcgcc ggccggctgc tcgcctcggc
    11881 cgggcgcaac gacctgctgc tgcataccgg ctgcgacagt gtggaggagg ccttcatgca
    11941 tctggtgacc tcggcggagg ccgccgagac ggggcggcgg cggccgggtg ccgagccggt
    12001 ccgggagccg ctgatcaccg acgtactcca cgatcccgac cggccctact tcgcttccga
    12061 gtccccgtgg tgagcggcgc ggcgggtccg gggacgggga cggggccgcg gctggccggg
    12121 cggcccttgc cgttcacgcc gagcatcacc gccgccacgg ctcaccgggt gttgcagcag
    12181 atctcccggg accggggcag cgccgcgctg atgctggtca tcccgtgcat gctcatggtg
    12241 ctgctgaagc tgatgttcca tgacgcggag gagtcgttcg agcgtgtcgg cccccaggtc
    12301 ttcggcatct tcccggtgat cgtcatgtac ctggtggcgt cggtctcgac cctgcgggaa
    12361 cgcacctcgg ggaccgccga acggctgctg acgctgccgg tgcagcggct cgacatcgtg
    12421 ctgggctaca gcctggcctt cgcgttcctg gcgatgctcc aggccgtcct gtcgacgctg
    12481 ctggcgatcg ggccgctggg gctggacatc aaggggccgg cctatctgct catggtcatc
    12541 gccatgctcg gcgccctgct ggggctggcg ctgggactgc tcgtgagcgc gttcgcgcgc
    12601 aatgagttcc aggcggtgca gttcctgccg gccggggtgc tgccgcagtt cctggtgtgc
    12661 gggctgttcg tgccgcgcga ggagatgcac ggctcgctgg acgcgttggc gcaggtcatg
    12721 ccgatgacgt acgcggtgca ggcggcgacc gaggccgccc ggcacgacgg ggtgaccggc
    12781 gtcttcgtcc gtgacgcgct gctgatcctg ctgtgcgtca tcggtgtcct ggtcgccagc
    12841 gcggccacgc tcaagcgctg acgacaaacg ggtggggtac ggccggccgg ccgtacccca
    12901 cccgctgtgc tgctgtcggt gccgcggtgg tcgtcagtag cggtcgtagt cgtcgcggtc
    12961 gtcacggttc gacgtgcccc acgcgaaccc agcggtgaca tggccgttgc gcgggacctc
    13021 gaagggcccg aagttcatcg gacggtcgtg gccgcgcctg ccgcccggac cgtcgatgtc
    13081 gacggcggga gacgacgggg cggcgaacgc ggagggcgcg gcgccgcccg cggccagtgt
    13141 gatcgctacg acggaaatcg ccgcggcacg acggaaaaac gacatggctg gctcctcagg
    13201 aaaggatgat cctcaacgga aatcacccta gccattgctg ctgtacggca gccgcgtatg
    13261 ccaggggaat gggtcgcttt tccctcgaag ggggctaccg gagtgacgtc atgacgaacc
    13321 ggatcaatag tgggatctcc ttttctttct ttggtggtgg gggtcggtgg cgggtgttcg
    13381 gtgtgtctta tttcgctctt ccgtagggtg aaacggtgaa atctcgcacc ttgttggttg
    13441 ctgcgctggc agccgtatgc gccgtgttcg gcgggccgcc gtgcgccgcc gaatcccttt
    13501 cgcagcggcc ccggaattac gaaccccagc cgccaccgcc gtggcagtcc tctcccgtgc
    13561 ccgtctggcg gccgccttcc tctcaccccg gcccggacgg cgccgtgcgc ccgtcctcga
    13621 agcggccggg tgggcctgag cggccgggtg ggcctgagag gccgggtggc gcggggcggc
    13681 ccggggggcc cggtgaggcc ggcaggccgg gtgcggcggg ggcgccgagc ggggtggggg
    13741 cgttgggggg cgtacgggcg gaggtggtcc ggctggtgaa ccaggagcgg tccagggccg
    13801 gttgtcccgc ggtgcggcag cacagcgccg tgaccaaggc cgcacagggg cacagcgcct
    13861 acatggcccg tacgggagcc ctttcccata cggggcacaa gggctccgat ccgggcagcc
    13921 ggctcacggc cgccggttac cgctggagcc gggccgggga gaacatcgtc gccgggcccg
    13981 aggacgccgc agcggccgtg cggtcgtgga tgaacagccc cgagcaccgt gagtccgtcc
    14041 tgacctgcca gttccgccat gccggtgtgg gcgtgggccg gggcccggac gggccctggt
    14101 ggaccctgct gttcgccgcg ccgcgctgac cgggagccgt cgtcaggcca ggtcctcgtc
    14161 ccaccaccag gcgatggtgg gcgcgccggg gggcggagtg gggcggctgt cggccggttc
    14221 ctccgcccac tccagcggcg tttcctccat ggcgtccggt acccgcccca ggctcaggta
    14281 gcgcggcacc cgcagccccc actcggcgtt cccccggatg ccgtggcgga gcccttgcag
    14341 atagttcgcc agggcggcac cggcgtgcgg ccggacccgg tcgtgcaggc gcgtgaagcg
    14401 gacgaggacc cggtccctga gccgggtcgc ggcctccacc gcctcgggca gcgacatcga
    14461 ctcgtggcac atgaggacgc tgtagatgtt ctggtccgtg tgcccccggg acaactcctt
    14521 gcgcagtgag tgcctgtcgt tgtccagcgc ggccacgaga atggccatct ccgtcagcgc
    14581 ccgcacggcc ggccggtgca gctcgttgtc cgggacctcc agcccggtgg ccagctccag
    14641 catggcgaag gtcggctcgc cgccgctgga cagcagcctc atggcgagga actcgtccag
    14701 ctccggcatc cggccggacg cctggttgcc cacctgccag cacacacccg acagccaggc
    14761 ccgctgggcg tgggtgaacc gccgtacctg tgccgccgta ccgaaggagc ggaagcgggc
    14821 gaggatgtcc tgcagggccg ggatgtagcg ctcgcccccg tccgtggccg atggcgcctc
    14881 ggctgcccgc tgcacccggc cggccagggc gttgaacagc gccggacggg cactcaacgg
    14941 cccgttgtcg cagcgggcgt cgtcgattcc gaacccccag tagacccaca gagatgtcgc
    15001 cagcagccgg tcgtcgtccg cgacgggcgc gaaccgggcg aagaagtccg tgctgtgcgt
    15061 cgccacgacc cacgcgcact cgtcgtccgt ggcgcacata ccgctgtcac ggatccactc
    15121 ctcggcctgc ttctccacct gacgcgcatg ggggtggacc gccgagtccc atggacagtg
    15181 gatgagcggc agatcggctt cggtgaggga aagtcccatg acacatcccg gtcgtcggtg
    15241 gcggagaagg agcccgcaca tcgtccggcg ccgttcgggt accacaacac gacatatggg
    15301 tgtttccttg ataaaacctc cgaaaagggc acctcctgtt tgtgcttgac gcgggtgcgg
    15361 gtgcgggtgc gggtgtgcgg gtgagggggg cgcgggtttc tggtgcgggt caggccttgg
    15421 ccgcccaggc gatgtagccg tcggggcgga ccaggacggt gtcctggcgg gtgctgttcg
    15481 cccagctcgc ccgtatgacc cggccgggca cggggattcg gggcgcctgg ggggcggcgc
    15541 cttgcggggc gacgaggacg aaccggccct tgcggagcag ttcgtacagc cgcccctcgg
    15601 tgagcgtcag gtccggggcg cgccggccca ccaggcggtg ggcgccgcgc tcggcgcggt
    15661 agctgatgcc gatgccgctg accatgccca tcgccttggc ggccgcggga cggaccgcgt
    15721 tcaggagacc ggcgccgagg gcgcgggcca tgcgctcgag ggggttgtgg gccatggcga
    15781 ggcggaccag ggcgccgctg ctgcgcagca ccatcgtgcc gacggggtgc cgctcggcgt
    15841 ggtagctgtc gagcagggcc tcggggtcgg gggcttcccc gcgcaggacg gatgcgagct
    15901 tccaggagag gttcgcggcg tcctggaggc cggtgttcat accctggccg ccggccgggg
    15961 agtggatgtg cgccgcgtcc ccggcgagga agacgcggcc ggaccggtag gcggggacct
    16021 ggcgctcgtc gctgtggaag cgggagatcc agcgggcgtc gtgcataccg aagtccgagc
    16081 cgagagcgag ccgggcgatc tcccgcacct catcgaggcc gaccggctcg ctgtcgggga
    16141 cctggcgttg gcggttccag cccatgaccc ggtaccagcc gtcgccgaag ggggcgatga
    16201 aggcgaaggt gtccccgacg ccgttgaccg tgagcagttc gtcgggctcc tcggcgaggc
    16261 ggacgtcggc gagcaccatg gagcggatga ccgagctgcc ggggaacggc aggcccaggt
    16321 cgcggcgcac ggcgctgcgg tggccgtcgg tgccgacgag gtagcgggcc cgcagtgtgc
    16381 cgggcgttcc gtccgcgccg gtgacctcgg cggtcaccgt gccgtcgtcc tggtgcaggg
    16441 cgcgcagctc cgtgccgtac ctgaagtcga cgcccgcggc gacggcgcgg cgctccagca
    16501 gtcgctcgac ctcgtactgc ggggtgatga gcaggaaggg gaagcgggag gggaggcggg
    16561 acaggtcgag cgacagcttg cggaagaacc gcagcccggt gacggacgtg cccttgtgga
    16621 ccagctcgtc cgccaggtcc cgggcgtcga gcagttccag ggtgcgggcg tggacgccga
    16681 acgcgcgcgt catgttgctg gtctcgtgcg gtcggcgctc gacgaccgtg acgttcacgc
    16741 ccgcggcggc gaggtcgccg gcgagcagca gtccggtggg ccccgcgccc accacgatga
    16801 cgtcgaactc cgtgccggcc gtgccgttca tggctgcctc ctgggtgcca acggtggatg
    16861 ggtcaacatc tgttggtcaa cgcttgttgg caacggtaga cccgtcggct ctggcgtgtc
    16921 aacggttgtt ggcctacagt tgttggcatg acgactcccc gtcgctccga caccacccgc
    16981 gccgccatcc tcgaggcggc ccgggagcgg ttcgcggccg atggctacga gcgcgccacc
    17041 atccgcgcca tcgcccgcga cgcggggatc gacccgtcga tggtgatgcg gtactacggc
    17101 aacaaggagg ggctcttcgc cgccgcctcc gagatcgacc tgcgcctccc cccgctcgga
    17161 gcgctgcccg cacagcacat cggcgccgtc ctcgtcacgc acttcctcga ccgctgggag
    17221 caggacgacg tgctgaccgg ggtgctgcgg gtcggcgtca ccaacgccgc gggcgccgag
    17281 cgcatgcgcg cggtgttcaa ggcgcagctg ggcccgatag cggccggcgt ctgccccgac
    17341 ccggccgacg ccccgcgccg cgccgccctc gccgcctcgc agattctcgg catggcactg
    17401 gcccggtacg tgctgcggct gccgcccgcc gtcgacatgt cgcgcgagga ggtgatcgcc
    17461 tggctcggcc ccacgatcca gcggtatctg accgccgacc ggccctgacc ggccctgaca
    17521 ggtccggccg gacaggcctc taggcggccg cgtcgccgaa ttcgcgcagc gcgtcctcga
    17581 cgatggcctc caggcgggag tggtgcgcgc cgcgccagta cacccggccg cactcggtgc
    17641 acttcgcgaa gacgtcgtac gtacgctgcg tgccctgctc caactggtcg cgcaccgcgt
    17701 ccttgtcggc gtcggccagc gggccgttgc aggccgtgca ccgcgtccac ggcgccagtg
    17761 gcggcgcgaa ccgctccagc acgtcccgca gttggtcctc cggccggtcg ctgtagacgt
    17821 acgccccggc ccacagctcg cggcgccgca gcagcccccg gtcgcgcgag agcatcacgc
    17881 gccgttcctt cgccgaccac gtggccagcg ccgcgtcgcc gatgtcctcg ctctcgtacg
    17941 ccgcgtcgac gccgagcagc cgcaaccgcc gcgccagcgt cccgaggtga acgtccagca
    18001 ggaacctgag cggcgcgccc ggcaccggct gcgggcgctc gacgccgagc acctggacgt
    18061 gctcgccggc cgccgggatg tgcgcgggcg tgaccgggcg gccgtcgacc agcagcaggc
    18121 ccgcctcggt gaggggcacg ccgagcgact cgaccacatg gccgagtgtg gacaccccgt
    18181 cggtgaccac gacggaacgc ccggcgcggc gcggggcggc gacgaagagg cccaggccgg
    18241 gcgcgaagct gatgtggatc tccggtccgt tcacgtcgcc agcatgccac cgggcccgcc
    18301 gggccagcca gatcatttcg ccgggtcagg gccgccggtg ggcgggccgc cggacggggc
    18361 ccgggcgccg ggcagcgcac cgcgatcacc gcacctcatg gtttcccgga cctgaaccat
    18421 cagcgcgagc ccggatcgcc cgcctccagg tccagccgcc agttgttgct ccgcagcagg
    18481 tgccccggcg ggtactcgaa gtcccgctcg ccgagcagct cgaaacccgc cttccggcac
    18541 accgcgttcg acggaccgtt gtccacggac gggaacgcgt gcagataccg gtgcttgcgc
    18601 gccgcccggg cccgatccgc cacggccacc gtcgccgccg tcgcgacgcc ccgcccctgg
    18661 aagccgccca gaaccgtcca cccggtctcg tacacccgcg tcccgtccca ggtctgctcc
    18721 cagaagccga tcacgcccac cgggacgccc tccggctcca gcacgatccg gaacatccgc
    18781 ccggcccccg agcggtccgc gctcaggtcc acgtaccgct ggtgccgctt gaccagctgt
    18841 tccgccgtct ccggccctcc caggtgggcc atcaactccg gcgcgttgac cgcccgcagc
    18901 aggtcgaagt cccgctccga ccacgcctcg agccgtaccg gcgacgctcc gctgcccatg
    18961 tgctcagggc cacaccaggc agtacggctg gtgccccgcc tcgtgcagcc gcaccgagaa
    19021 gtcctgccac tcgtgcagca gctggtacac gttgaacgcg tcccgaggcc cgccgcggtc
    19081 cgggaccgtc gaccagatga acgccgccgc gcccaccgac tcctcgccga tgccgcgcag
    19141 cgggtcgacc accgtcatcg gcagcttcac caccgcgtag tcggggtgca gcaccaccag
    19201 ctccagcggc ggcaccttgt gcagcggcat gccctggatg ccggtcagca ccatcgcggc
    19261 tatggtctcc ggtttgatct tggtgaacat gccgcccata ccgagttcgt cgccgcccaa
    19321 ttcctcgggc cgcatcgaga tcggtacgcg ggcggcggtc gcgccattgg gcgcgccgaa
    19381 gtacttgtac gtcaccccca tgccccggcc acccccgctt ccgccgccca tcggccccaa
    19441 ggaggctctg tcctgcgagg ctttgtcctg ctcgcgccgg tgcttccccc gccgggcagg
    19501 ctcgggtccc aggtcgtcgg tcccctcgcc cagtccgcca ccgcgatgca tatctccacc
    19561 cgactgcttt ttaggtaaca cagcccccgc cgcgcaaccc gatcatcgtg acagtgacct
    19621 cccccgcgga cgtgcggtga aacacctgtc cgcaagaacg tccgggcctc tgacaccatg
    19681 gattccgtga gcattcccta tgacgcccca gtttcgcaga cccggaggtc cggcgcctcg
    19741 tcgtaaacaa cgtcgcgggc aggcgaagcg ttcaaggaag gcccactggt gtcgtcccgg
    19801 ccgccatgcc cgagcattgc tgccgtcaac tcgttctcgc aggtcaggac caacgtgccg
    19861 tattcatacg aagccccagt ctcacagacg cttttcgacc gcgcgtccct cgtgacgccc
    19921 ggcggcgtga actctcccgt acgggccttc cgggccgtgg gcggtacgcc ccggttcatg
    19981 gtgtccggta cgggtccgta cctcaacgac gcggacgggc gtgagtacgt cgatctcgtc
    20041 tgctcgtggg ggccgatgat cctcggccac gcgcaccccg aggtgatcgc tgccgtccag
    20101 gaggcggtgg cccgtggcac ctccttcggt acgcccgggg agggcgaggt ggccctcgcc
    20161 gaggagatcg tggcccggat cgagcccgtc gagcaggtac gtctggtgtc gtccggcacc
    20221 gaggcgacga tgtccgcgat ccgcctcgcc cgcggcttca ccggccgcgc gaaggtgatc
    20281 aagttcgccg gctgctacca cgggcacgtg gacgcgctgc tggccgccgc cggctcgggc
    20341 gtcgccacct tcgggctgcc cgacacgccc ggcgtcaccg gcgcgcaggc gggcgacacg
    20401 atcgtgctgc cgtacaacga cctcgacgcc gtacgccagg ccttcgccgc gcaccccggc
    20461 gagatcgcct gcgtgatcac cgaggcctcg cccggcaaca tgggcgtggt cccgccgcgc
    20521 gacggcttca acgccggtct gaaggagatc tgcgccgaga acggcgccct gtacatctcc
    20581 gacgaggtca tgaccggctt ccgtacgtcg aaggccggct ggtacggcgt cgacggcgtc
    20641 gcgcccgacc tgatgacctt cggcaaggtc atgggcggtg gcttcccggc cgccgcgttc
    20701 ggcggccgcg ccgacgtcat ggcccacctg gccccggccg gccccgtcta ccaggcgggc
    20761 accctgtccg ggaacccggt cgccaccgcc gccggtctgg cgcagctgcg gctgctcgac
    20821 gacgcggcgt acgagaaggt gaacgccgtc tcgcgcgaga tccagggcct ggtgacccag
    20881 gcgctggcca aggagggcgt ggcgcaccgc ctccagaccg cgagcaacat gttctccgtc
    20941 ttcttcaccg acgcggaggt cgtgaactac gacgacgcga agaagcagga ggcgttccgc
    21001 ttcaccgcgt tcttccactc gatgctggcg cagggtgtct acctgccgcc gtccgcgttc
    21061 gagtcgtggt tcgtgtccac ggcgcacgac gagcgcgcgg tggagcggat cgccgccgcg
    21121 ctgccggccg ccgcccgcgc cgcggcggag gccaccgtat gaccggcaac gacgagatca
    21181 ccgtcgtcca cctgatgcgc cacggcgagg tgcacaaccc ggacgggatc ctgtacgggc
    21241 gccgggcggg ctaccacctg tccgagctcg gccggcagat ggccgaccgg gtcgccgagc
    21301 acctggcggg gcgggacgtc acgtacgtcg ccgcctcccc gctggagcgc gcccaggaga
    21361 ccgcccagcc gatcgccaag tcgcacgggc tggacctcgc caccgacgag cggctgatcg
    21421 aggcgggcaa cgtcttcgag ggcaagacgt tcggcgtggg cgacggcgcg ctgcgccggc
    21481 cgtcgaactg gcggcacctg accaatccgt tccggccgtc ctggggcgag ccgtacatcg
    21541 accaggtcgt ccggatgatg ggcgcgctga acgcggcgcg ggacgcggcc cggggccatg
    21601 aggcggtgtg cgtcagccac cagctgccga tctggatcgt ccggagcttc gtcgagcggc
    21661 ggcggctgtg gcacgacccg cgtcgccggc agtgcacgct cgcgtccctc accacgttca
    21721 cctaccaggg cgacaagatc gtctcggtcg gctacagcga gcccgcccgc gacctcgtcc
    21781 cgccgcacct gctggccggt gccaagccgg cgaagggcaa gtccaaagcc ttcggcgcct
    21841 gacccctgcc cccaccgggc gccgccgccc cctcggggcc ggccggcgcc ccggggcggc
    21901 gcgcgcccgc gcggccactt tgccgtcggc cccggtcccg gcggatggac ctcgtcccgt
    21961 cccaggctcg cccgggccgc agagcctgtg cccggcgcac gcgcccgcag cgccgggcgc
    22021 ggcgcgcgcc cttcgcgccc cgccgcggtg cccgcgcccg cgcgccgcca ctcccggcct
    22081 tggccccgct cgcggcgacc ggctccctcc cgtcccggat ttggcccgcc cgcgcgcccg
    22141 cgcgccgctc ggccttcggc cccggccctg gcggatggac ctcgtcccgt cctaggctcg
    22201 cccaggccgc aaagcccgtg cccgccgcgc ccgtgcccgc cgcgcccgtg cccgccgcgc
    22261 ccgtgcccgc cgcgcccgtg cccgccgcgc tgggcgctgg gcgccgggcg cgccccgccg
    22321 cgcggccttc gcgccccgcc gtggcgcccg cgcgcggcca cccgggcctt cggccccgtg
    22381 ccagcgcccg ggtctcatcc gccccttgcc cgggccccgg agctcccgcg tccgcagctc
    22441 ccggacccgt agagcgcgga tccgcagccg tcgacccggg tgtcgacggc cagatctcgt
    22501 caccccgagc ttgcccgaag cgcccgaagc gcgcgtccgc aacgcccgcg cccgcgcgcc
    22561 ccccgcccgc cgcgcccgcc cgccgcgccc gccgcgcccg cgcccgcaac gcccgccccc
    22621 gccccgcccg cgcacacgcc cgtgtcgtca agctgcgggt aacggtcccg tcacgcaggg
    22681 gattgtgtgg taatcggggg aaccgccctc ttccttctgc cctctcacac attgccggtt
    22741 tggaaggtat gtccggcaac gagcgagcgc ggatggggac gatatgcgcg ggatcagtcg
    22801 aaggggcctg ctgggagccg gagttggcgc cgcggccgcg atgggggtcg gtggctgcgg
    22861 gttgggcggc ggctcggaca agcccgggag cgggcccggc gagggtgggc agaaaggtac
    22921 ggcccccggc aaggtagagg ggcgtctcat aggggacggt tccacgtccg acaccggaaa
    22981 gcagcccaac cagcccgaca ggcccgtccc cctggagccc gggcagaccc cgccgcagtt
    23041 cgtgatcttc tcctgggacg gcgccggcga ggtcggcaac ggcctcttcc cgcgctttct
    23101 cgagctcgcc aagaaccacg acgcgggcat gaccttcttc ctctccgggc tctacctcct
    23161 gcccgaatcg aagaagaccc tctaccgccc gccgaacaac cgccccggcg cctccgacat
    23221 cggttacctc accgacgacc acatcaagca gacgctgacg tacgtccgcc aggcctggct
    23281 cgacgggcac gagataggca cccacttcaa cggccacttc tgcgccggct ccggctcggt
    23341 cgagaagtgg accccggccg actggcagag cgaaatcgac caggcggtga aattcgtcac
    23401 cgaatggaag accaacagcg gctggaccga cctcgacccg ctgcccttcg actaccgcaa
    23461 ggaactcgtc ggcgcccgca ccccctgcct cctcggccag gacaacctcc tgcccaccgc
    23521 caagaagctc ggctggcgct acgacgccag ctcgcccggc ggccaccaga agtggcccgt
    23581 caagcgccag ggcatctggg acctgccgct ccagcagatc cccttccccg gccgctcctt
    23641 cgaggtcctg tccatggact acaacatgct cgccaaccag tcgaagaaca cgaccaaggg
    23701 catgccgtcg cgctatccgg aatggaagaa gcaggccacc gaggcctacc tcgccggatt
    23761 cacccgcgcc tacgaatcga atcgcgcgcc cctctacatc ggcaaccact tcgagcagtg
    23821 gaacggcggc atctacatgg acgccgtcga agaagccctc aagggcatgg ccgggaagaa
    23881 ggacgtaagg ctcgtgtcgt tcaagcagtt cgtcgactgg ctggacgtcc aggacccggg
    23941 gatcctcgac aagctccgta cgctcgaagt cggccaatcg ccggcgggcg gctggaacac
    24001 cttccttaag cccgcctgac atcgggcttt acgggcaggc aggggggcgc gcaagatccc
    24061 cgaaacgtac atgcgaaact tttcacatga gccttagccg cgccccccga ggcctcctgc
    24121 tcaccgccgg cgccgccctt gcggccgcgc tcacgctggc cgcgtgcagc ggcgactcca
    24181 acggcacgtc cggtggtggc ggcaacacca acttcgtcac caacaccggc ggtatcgaca
    24241 ccgtcgccaa gggcgagcgc acggctccca acaagctcgc gggcaccacc ctcgacggca
    24301 agcccctcga cgtcgccgac ctcaagggca aggtcgtcgt gctgaacgcc tggggctcct
    24361 ggtgcggccc ctgccgggcc gaggcgaagc acttcaccaa ggtcgccacc gacctcaagt
    24421 ccgagggcgt ggagttcgtc ggcatcaaca cccgcgaccc caacaagcag cccgccctcg
    24481 ccttcgagaa ggacttcgcg gtcccctacc cgagcctgta cgacccggcc ggcgagctga
    24541 tcctcaacgg cttccccaag ggcacgctca acccgcaggg catcccctcc accgtcgtcc
    24601 tcgaccgtga cggaaagatc gcggcacgcg cgctcatgcc gctcaacgaa accaagctgc
    24661 gcaagatgat cgacccgatc gcggccgaga aggcctcggg gaactagccg atgtacaacg
    24721 agacggtctc cagcggggcc ctcctgctcg ccctgcccat cgcggtgctc ggcgggctgg
    24781 tctccttctt ctcgccctgc gtcctgccgc tcgtgcccgg ctacctcagt tacgtgaccg
    24841 gcgtcaccgg caccgacctg gccgaggccc ggcggggccg gatggccgcc ggcgcggccc
    24901 tcttcgtcct cggcttctcc gccgtcttcg tctccggcgg cgccctcttc ggctacttcg
    24961 gctggaccct ccaggaacac cgcgaaacgc tcaccaccgt cctcggcgtc ctgatggtcc
    25021 tgatgggcgt cttcttcctg ggactcatgc cgtggttcac ccagcgggag ttccgcttcc
    25081 acaagcggcc ggtgaccggg ctggccggtg cgccgctgct gggtgccctg ttcggcatcg
    25141 gctggacgcc gtgcatcggc ccgacgctcg cctccgtcca ggccctcgcc gccaacgagg
    25201 ccagcgcggg gcgcggggc
//
