LOCUS       NZ_LIYH01000001        22688 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB03234 scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_LIYH01000001
VERSION     NZ_LIYH01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB03234
  ORGANISM  Streptomyces sp. CB03234
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1475216)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1475216)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905885.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:52:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,127
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,894
            CDSs (with protein)               :: 6,894
            Genes (RNA)                       :: 74
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 159
            CDSs (without protein)            :: 159
            Pseudo Genes (ambiguous residues) :: 0 of 159
            Pseudo Genes (frameshifted)       :: 70 of 159
            Pseudo Genes (incomplete)         :: 112 of 159
            Pseudo Genes (internal stop)      :: 10 of 159
            Pseudo Genes (multiple problems)  :: 33 of 159
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 862179
            Orig. end                         :: 884867
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIYH01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22688
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="6"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22688
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22688
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12688](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12688)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     ncRNA           236..637
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="AMK26_RS03920"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="AMK26_06595"
                     /product="RNase P RNA component class A"
     gene            236..637
                     /gene="rnpB"
                     /locus_tag="AMK26_RS03920"
                     /old_locus_tag="AMK26_06595"
     misc_feature    complement(341..353)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(849..864)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.37"
                     /tool="antismash"
     gene            complement(933..1820)
                     /locus_tag="AMK26_RS03925"
                     /old_locus_tag="AMK26_03875"
     CDS             complement(933..1820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677423.1"
                     /locus_tag="AMK26_RS03925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03875"
                     /product="hypothetical protein"
                     /protein_id="WP_073751907.1"
                     /transl_table=11
                     /translation="MPEDLLNQQAGTVHEETARNAGKPGHTPDQPTEGDQPRDGAGTEG
                     AMKLMTRQAEAIRAHVLQHSTEDFMQRLAARITSEARRPARIQYAPAGPAAGAHDPYPG
                     ETTEITQLPAPAAGPLPRTLRPDGRPQPRRPRARRRRPTPINTSDPAKSQYLAFGYVTE
                     LCSTVLRSAEIDTLAAFAADYDEAGARTFGCLLYSLDKRESAMYWWRFAAGAGDPLAAH
                     LLAAHHAATGPSTDSRAWCAFSRMLGFRADRHVPKPVRHRTELAENFAREIPLRDETRL
                     FMRYPHLPQGLAAR"
     gene            complement(1820..2389)
                     /locus_tag="AMK26_RS03930"
                     /old_locus_tag="AMK26_03880"
     CDS             complement(1820..2389)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447152.1"
                     /locus_tag="AMK26_RS03930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03880"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_073751909.1"
                     /transl_table=11
                     /translation="MNDPFGKERDLVGPDPGQPGLDPRGEEFFRENLDTFMRIAAYRLR
                     NLHDAEDALMEAMVTMHRRIERILAASNPIALATKILNDAITDYYRSSVRITKYEHLVA
                     EMPAASALTELGRYDRLDRAMEQLEVIAPQQARCVQMYYLIGLSYAQTAEILGITQSAA
                     KTAACRGRQQLTELMLTELPKEKGDS"
     misc_feature    complement(2725..2740)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.2"
                     /tool="antismash"
     misc_feature    2798..2813
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            2945..3703
                     /locus_tag="AMK26_RS03935"
                     /old_locus_tag="AMK26_03885"
     CDS             2945..3703
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638632.1"
                     /locus_tag="AMK26_RS03935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03885"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073751911.1"
                     /transl_table=11
                     /translation="MSRWKELPAALDDSERQLLVQLRRLKDRSGLSLAALANRTGYSRS
                     SWERYLNGKQPVPREAVEELAQVCGTDPTRLVVLHQVAARTRKGGGPGEPAPSGPSTSP
                     APREPRPARTLPMRRTLAAAIAAVAVSFGAGLMTAGAWDDGAPVTTTGTRAATTGYLRG
                     QTYSCDIQRGNGELRAGHSDTRAMLLDINSTGFDVVEAQCLLREHGFDPKAFDGLYDER
                     TQAATKAFQAKRGLVADGIIGPDTWGELRR"
     misc_feature    3008..3010
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3700..4497
                     /locus_tag="AMK26_RS36895"
                     /old_locus_tag="AMK26_03890"
     CDS             3700..4497
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022355.4"
                     /locus_tag="AMK26_RS36895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03890"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_073751913.1"
                     /transl_table=11
                     /translation="MITGAACEELVTELRRARERSGLSMAALAARTPYSKSSWERYLNG
                     KKPVPRGAVEALCRITREPAEPLLALWELADATWSGRGRHPGGAVPSAPSVTAPGGRPA
                     ARRGRWAGFAGAAVALSLAVLGVSMAGTRQDPPRAAAEPPVRNPGCTAEACEGRNPVDM
                     GCGGSGMVQTLARRTASEGRRLELRHAEVCRALWVRATGLEAGDRVELRLSDGRLQYVT
                     AEAGPEAGRYLSTPMSSDTGTGTTGVRVCLKAASSGREECFTG"
     gene            4715..5188
                     /locus_tag="AMK26_RS03945"
                     /old_locus_tag="AMK26_03895"
     CDS             4715..5188
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS03945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_03895"
                     /product="hypothetical protein"
                     /protein_id="WP_073751915.1"
                     /transl_table=11
                     /translation="MNTRTKLAALALTAGVVTATGGATAPAAVALTTPAAHSVVQPAAA
                     TPADNGDVRAAGSGSADRTLRTSNGAGSVRVKWTWHSSANGKSYYGSFWGTFYDHAPKD
                     KKYVLLQAKWQGKGWTTIRTAAKGGTFSGDYSGLKGLNFRACLQGGKCGAPAW"
     misc_feature    complement(5290..5304)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.16"
                     /tool="antismash"
     misc_feature    5361..5375
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.75"
                     /tool="antismash"
     gene            5411..6016
                     /locus_tag="AMK26_RS03950"
                     /old_locus_tag="AMK26_03900"
     CDS             5411..6016
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478956.1"
                     /locus_tag="AMK26_RS03950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03900"
                     /product="response regulator transcription factor"
                     /protein_id="WP_073751917.1"
                     /transl_table=11
                     /translation="MIRVLLVGKTRLVRGALAALLSREEDIDVVAEAEGDGELVARAML
                     CRPDVAVIDVDCKEGEEFAAKGELTAQLPDCRMLLMMASPTPERLRRMLDLHAAGVIST
                     NAPADRLVHGVRKLVRGQRFIDPEFALVALDAGDNPLTPREVEVLRMAADGTPTGEIAQ
                     RLSLSVATVRNHLSAITRKAGARNRIDAIRIARESGWV"
     gene            complement(5946..7886)
                     /locus_tag="AMK26_RS03955"
                     /old_locus_tag="AMK26_03905"
     CDS             complement(5946..7886)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478549.1"
                     /locus_tag="AMK26_RS03955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03905"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073751919.1"
                     /transl_table=11
                     /translation="MKGRPGDLLRASLRRRRREYLRLTGWSLVQAVPAFLSGLAVARAV
                     DQGFLAGRPGVGFAWLGLLAGAFIVGAWGTRHAVLGLAALIEPFRDELVTLVTTGTLDR
                     STRLGGAADTAGVARLTEHVEIAREAYGAVVMFVQGFLVTAVTVLLGLATLDPAFLVLV
                     LPPLLLGLGLFLAALRAMVARQRAVILANERISETASAVTGGLRDVIACGADERVRART
                     GAQVDDAARATRALARLTALRTAALGIGGWVPLVLILAGAPWLVRNGVTAGAILGALTY
                     VSQSLSPALQNFVQELGSSGLWLLVTIGRIAEVAPGAPAPALPPSGPGPEPEPEPEPGA
                     EPGAEPGAVPERAPEPDRSPPVPPPGAPPSHPAHPARPARPRDSRVELHGVTFRYARSA
                     EPVVQDLDLDLRPGEHLAVVGPSGAGKSTLAALTAGVLAPQAGQIRLGGVPVLALDGED
                     LARHRVLIPQEAYVFAGTLRENLTYLAPGAAPAEVESAVRAVGAAALVEKLGGYDTPLD
                     PRELSAGERQLIALARALLPAPRLALLDEATCHLDPVAEAVAEEAFARGPGTLMVVAHR
                     ISSALRADRVLVMDGTRVSLGTHDELMAGSALYRDLVGHWDGADPSAVTPSPTPALSGS
                     RRSCSAPRLSW"
     gene            complement(7883..9616)
                     /locus_tag="AMK26_RS03960"
                     /old_locus_tag="AMK26_03910"
     CDS             complement(7883..9616)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478548.1"
                     /locus_tag="AMK26_RS03960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03910"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073751921.1"
                     /transl_table=11
                     /translation="MDRRAADRLLLAAARRGGPWLGVMLVTSLLISGAGVVLPAVMGRT
                     LDAVLGDQDAARWLALSAALIFVLVAADALDDYVGEVTEARSTAWLRHTLLRHILALGT
                     RATRRFDSGDLVSRLVGNTSETGRVASGVVWAFMNLVPPIGAIVALALIDPWLCLTFLV
                     GLPVLAPLVRAFIRDISDLNERYFDTQGRIAARLTDALTGSRTIAAAKTVDREARRVLA
                     PLPELHRHGMGMWRSLARMSAREDLVVPLVMVAVIAVAGLELARGRITPGEVLAASQYV
                     VMATGIGSVVGTLNQLVQARATAGRLAEVFAEPPVEYGSEHLPDGRGRLEFRGVTVRAG
                     GDTVLEDLDLTVPGGALVAVVGRSGSGKSLLAALAGRLVDPDEGEVLLDGVPLRRVDRG
                     ELRRAVGYGFERPVLLGETFADAIGFGPRTPATEELVAHATAARADAFIRHMPAGYDTR
                     LADAPISGGEAQRVGLARAFTQAGRVLVLDDVAASLDTVTEHHISQVLTGALADRTRLI
                     VTHRASTAARAELVIWLADGGVRARGRHRDLWADPDYRAAFQADAAAGRVPQTADVGGT
                     R"
     misc_feature    9729..9744
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     misc_feature    9752..9767
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     misc_feature    9775..9790
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     misc_feature    9798..9813
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            complement(9861..10004)
                     /locus_tag="AMK26_RS36040"
     CDS             complement(9861..10004)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033212.1"
                     /locus_tag="AMK26_RS36040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_107420853.1"
                     /transl_table=11
                     /translation="MTLLDLQGLDMPDAETAAHGSNSSASCRGGIAVRVKVGKLIKVRV
                     RL"
     gene            complement(10001..12688)
                     /gene="lanKC"
                     /locus_tag="AMK26_RS03965"
                     /old_locus_tag="AMK26_03915"
     CDS             complement(10001..12688)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040503.1"
                     /locus_tag="AMK26_RS03965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03915"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_241837810.1"
                     /sec_met_domain="micKC (E-value: 8e-252, bitscore: 834.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7e-12, bitscore: 41.1,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYEAFCLTDPLFYDTPARAGDTAADSDSDSDSDSDSDFEQTRCP
                     VPDTWVREDLDDWVVLHPDGAELPPQGWKVHVSACLDNAEEILGAVWDYCITRRISFKF
                     RPGLDALLNANIKYAPRGASGKFVTIYPADEARLKDVLTDLDGVLHGRPGPYILSDLRW
                     ASGPLYVRYGGFARRYCVSPATGETVLAVEDASGRLVPDLRKPVFEVPEWVTLPGFLEP
                     HLAARAGTTVADLPYRIEKALHFSNGGGLYAAQDTRTGERVVLKEARPYAGLTPDGADA
                     VSRLHRERETLERLRGLDCVPALHDHFVLGDHHFLAEEFVEGQPLTDLFRERYPLSSVE
                     PDGPDQTDDTAAVAYTSWAVDLVGRVERSVAAVHDRGLVLGDLHPSNILVRPDGRVVLI
                     DFEGAADAAEERPQTLAAPGFQAPGELTGFAIDRYALACLRLSLFMPLTQLIELDRAKA
                     AQLAREARRSFPVPRAFLDEAVRVITGSDGRTPAAGTEPRLEADHDGWLRARSSMTAAI
                     LAAATPRRDDRLFPGDIEQFRAPGGGLGLAYGAAGVLYALDVTGAGRHPRYEEWLVHRA
                     VRAEEGTRGGFYDGLHGVAHVLDHLGHRDAAMKVLDICMGDDQWQELGLDLHGGLAGIG
                     LNLQHFAAVTGEPAFHDAAMNVAQSVADRLGPADGVPETSGGKYPYAGLMRGSSGPALL
                     FLRLYEHTGDPAFLDLAGTALRRDLRRCVVRKNGGMQVDEGWRTVPYLAEGSAGIGLVL
                     DEYLTHHGDDRFEAAAAEIRRAAAVQFSVQPGLFRGTAGLILYLSRAHPAGTAAGRDPL
                     VAAHVRHLSRQALMLRGHLVFPGEELMRLSMDLATGSAGVLLALGAALHHHPVHLPFLG
                     TPSADGTRHTVQPPVLAKKGGDIT"
     misc_feature    12826..12839
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.71"
                     /tool="antismash"
     gene            13089..14102
                     /locus_tag="AMK26_RS03970"
                     /old_locus_tag="AMK26_03920"
     CDS             13089..14102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969493.1"
                     /locus_tag="AMK26_RS03970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03920"
                     /product="hypothetical protein"
                     /protein_id="WP_073751923.1"
                     /transl_table=11
                     /translation="MIFGKDGFLRAVDAFETAVRAHDADGAEGAYAGLHKTYEQARDDE
                     FLAAGPRLAELLAEVPPGPRAVVAVITGACVERGADPVACAPGVLGGVRGALQAAEAFC
                     ERWAATGGGDLPQPEADELTDEIVDRTGFEAAMGWWSLPQWEMAALAMLNSKAVRQQVP
                     GKAELLALAERVQDASGHPFKCLVYALRVLDDEPLVVLHRETRTGYAMRMTGIGDNFQL
                     HTLLAGALIGGLHLPGDAPSAQEVAVCRDAPGQVDTAGSFNLVGADGGWIWNEGTPSDI
                     PVVDGARLLVLDPPPYRRGWAAGRFFPDMTGDLVLERVLGAEETERWFRHVAEAKD"
     gene            14207..14530
                     /locus_tag="AMK26_RS03975"
                     /old_locus_tag="AMK26_03925"
     CDS             14207..14530
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033172.1"
                     /locus_tag="AMK26_RS03975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03925"
                     /product="hypothetical protein"
                     /protein_id="WP_073751925.1"
                     /transl_table=11
                     /translation="MTVPVDQLTDPAVRAFVGAVNASDQQAFYAALTPGATMSDDGSDR
                     DLRQWAEREIFSVNGHMDVESEQADGLSLIARYRNDTWGEMRTAWRFVVEGGKVSRFET
                     GQA"
     gene            complement(14592..15344)
                     /locus_tag="AMK26_RS03980"
                     /old_locus_tag="AMK26_03930"
     CDS             complement(14592..15344)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-172). E-value: 1.3e-11. Score:
                     36.7. Matches aSDomain:
                     nrpspksdomains_AMK26_RS03980_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885803.1"
                     /locus_tag="AMK26_RS03980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03930"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_073753010.1"
                     /sec_met_domain="adh_short (E-value: 9e-34, bitscore:
                     113.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVHGIAVVTGAGSGIGRSVALALAEDGWALALAGRRAEPLEET
                     AALAGVDALCVPTDVTSPDAVTALFAAVRDRFGRVDLLFNNAGSFAGGGTPVEDLEYET
                     WRSVVDVNLTGAFLCAQAAYRQMKDQSPQGGRIINNGSISAHVPRPHSTAYTATKHAMT
                     GLTKSLSLDGRPYRIACGQIDIGNAATDMTQRMETGILQANGQLAVEPVMDAADVARTV
                     AHMAALPLEANVQFATVLATTMPYIGRG"
     aSDomain        complement(14829..15326)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK26_RS03980_PKS_KR.1"
                     /evalue="1.30E-11"
                     /label="AMK26_RS03980_PKS_KR.1"
                     /locus_tag="AMK26_RS03980"
                     /protein_end="172"
                     /protein_start="6"
                     /score="36.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="IAVVTGAGSGIGRSVALALAEDGWALALAGRRAEPLEETAALAGV
                     DALCVPTDVTSPDAVTALFAAVRDRFGRVDLLFNNAGSFAGGGTPVEDLEYETWRSVVD
                     VNLTGAFLCAQAAYRQMKDQSPQGGRIINNGSISAHVPRPHSTAYTATKHAMTGLTKSL
                     SLD"
     CDS_motif       complement(15231..15320)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK26_RS03980_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK26_RS03980"
                     /protein_end="38"
                     /protein_start="8"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VVTGAGSGIGRSVALALAEDGWALALAGRR"
     gene            15467..17104
                     /locus_tag="AMK26_RS03985"
                     /old_locus_tag="AMK26_03935"
     CDS             15467..17104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005318372.1"
                     /locus_tag="AMK26_RS03985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03935"
                     /product="alkaline phosphatase D family protein"
                     /protein_id="WP_073751927.1"
                     /transl_table=11
                     /translation="MTPADRSSAQHAPELRAAARHFGRRGFLTVTGAAAALAFSVNLPG
                     TAHAAEADPRKITEDPFTLGVASGDPLPGSVLLWTRLAPRPYEPGSGMPRARVRVHWEL
                     AHDARFARIARRGQATAHPELDHSVHVEVPGLGTDRVYYYRFRAGTWISPTGRTRTAPH
                     PGARAGELKLAAVSCQAYHDGYFTAYRHLADEDLDAVFHLGDYLYEYAVGATGGARNYT
                     DRQLPAHFNRETITLEDYRLRYGLYKSDPDLKAAHAAHAFVVTWDDHETENNYAGGIPE
                     NGVPPEEFLLRRAAAYRAYWENQPLRAPQRPTGPDMRLYRRLRFGRLAQFDILDTRQYR
                     SNQAYGDGWQTPGPESEDPSRTMTGAEQERWLLDGWQESDAVWNVVPQQVTFAQRRNVP
                     TPDFKLSMDAWDGYPASRRRVMDGAAAAGIENLVVLTGDVHVGYAFDLKADFDDPESRT
                     VGTEIVATSIASGKDGADRPANWDNLTRANPHLKYYNGRRGYVTVTLTGERARADYRTV
                     SHVTTPGAPVTTAASFVTEAGDPGLKPV"
     gene            17202..18623
                     /locus_tag="AMK26_RS03990"
                     /old_locus_tag="AMK26_03940"
     CDS             17202..18623
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969499.1"
                     /locus_tag="AMK26_RS03990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03940"
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_073751929.1"
                     /transl_table=11
                     /translation="MPESGPSTPGHIPTERPKAAIPAPTGADDPAGPGTGAGDPPGPGA
                     GPGTDTGTGAPAAAPPAAEGTGPVAARRVGLLVTLVLGGLTALPPLSMDMYLPALPEVT
                     QALHAPAATVQLTLTACLAGMALGQLVVGPMSDKWGRRRPLLVGMLLYIAATAVCALAP
                     SPELLIAFRLLQGLAGAAGIVIARAVVRDLYDGVEMARFFSTLMLISGAAPIVAPLIGG
                     QILRITDWRGVFHVLTLVGVLLTLVVWKWLGETLPRAKRHSGGVGEALRTMRGLLADRV
                     FSGYMLAGGLAFAALFAYISASPFVVQEIYGASPQTFSLLFGINSVGLVAVGQINGKLL
                     VGRVSMDKVLGFGLVVIALAAGALLLMTSGVFGHVGLVPVAAGLFVLMSAMGVTLPNTN
                     AQALMRTPHAAGSASALLGTSSFLVGAVASPLVGIAGEATAVPMAVVQLVCALGAVACF
                     MGLCRPWQDRQAVRA"
     gene            complement(18605..19885)
                     /locus_tag="AMK26_RS03995"
                     /old_locus_tag="AMK26_03945"
     CDS             complement(18605..19885)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486825.1"
                     /locus_tag="AMK26_RS03995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03945"
                     /product="hypothetical protein"
                     /protein_id="WP_073751931.1"
                     /transl_table=11
                     /translation="MALVAGVAVLALLLLLATCGTGDQRPSVPPAKAGAAPVTRLTVPD
                     AYDTSRGWDITGVSPEYVIARTTGVIAYLERVDDTRFRLRTLDARTGRHGWAGRPWRPL
                     GDPESFPGLLALEKEGRRFFVTWSYGRTGDDPLTTAGSFVSLDLYDAADGTRQRVEVPW
                     ADVPIVTGTGPGVLISDGRTRSAVVAPDTGEVSTVPPQRLGHPKGCAECRRLTAVRGVT
                     SKGLLVSGARGFWVPGGWFSRDRAPAGADPASGVPGSLTSGHVLARWQHKKGAARAATH
                     DIWAVHEARTGRPLVKAECRRPAIEPGEYPQAVVSPGGRYLIAGSLAFDLDARTGRCFE
                     EADGSTPLTLTTVTDGGVAYGASGARSVADALAGGGSPVAVDLATGVPQALAPSVRLPA
                     AEVAGVGVYRWTDARDRVHLTGYARTA"
     gene            20187..21176
                     /locus_tag="AMK26_RS04000"
                     /old_locus_tag="AMK26_03950"
     CDS             20187..21176
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518492.1"
                     /locus_tag="AMK26_RS04000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK26_03950"
                     /product="small ribosomal subunit Rsm22 family protein"
                     /protein_id="WP_073753012.1"
                     /transl_table=11
                     /translation="MNVSLSTADALRGALAGLLDGLPPTQAAQAVDRLIAHYRGTVPTG
                     APVLRDRSDVAAYAAYRMPATFEAVRAALAALRDAAPEWVPGTHTDIGGGTGAASWAVA
                     EAWDAAARTTVLDWAEPALALGRELAAASGIPSLEATAWQRARISAALRVESTDLVTVS
                     YVLNELTEQDRTSVVTEAARAAQAVVIVEPGTPGGYARIIAARDLLIAAGLTIAAPCPH
                     SGACPIEPGTDWCHFAARVSRSSLHRQVKGGSLAYEDEKFAYVVATRFPVAPATARVTR
                     KPQIRKGQVLLDLCTEDDGLRRDTVTKRHGTLYKAARDAAWGDEWPPR"
     gene            21299..21817
                     /locus_tag="AMK26_RS04005"
                     /old_locus_tag="AMK26_03955"
     CDS             21299..21817
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK26_RS04005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK26_03955"
                     /product="hypothetical protein"
                     /protein_id="WP_073751933.1"
                     /transl_table=11
                     /translation="MLRTRSRRFTACVLTAASAMLATTALTFTADAAPKPTPKDAPKDS
                     VKVLDWLADKQSDTKPDRLRVGSEWTAHAHLYTHKKGRPGKKIGDASSRCSVVDLTRHG
                     YVALCHRVLRTDDGSISLSDSIDRFGRYPHGGRSAVTGGTGKYVDAEGEAEITFIDGDL
                     ARFRILLDD"
ORIGIN
        1 ggaccgcgag accaagcggc gctgctatgc ccgtggcggc atcccgctgt acctgttggt
       61 cgaccgcgag ggctcttcgg tgaccctttt cagcgacccg gagggcgagg actaccgcca
      121 ggtcgtcacg atgcccttcg gcaagccgct gcctctcccc gagccgttcg gcttcgacct
      181 ggagaccgcc gacttcctct gacccgctgc cgggtaccat ggtcggcacg gcagacgagc
      241 cgggcggacg gccgcgtgga gacccttcgg gggtcttccc gaggaacgtc cgggctccac
      301 agggcagggt ggtggctaac ggccacccgg ggtgacccgc gggacagtgc cacagaaagc
      361 agaccgccgg ggacctcggt cctcggtaag ggtgaaacgg tggtgtaaga gaccaccagt
      421 gcccagggtg acctgggcag ctaggtaaac cccacccgga gcaaggtcaa gaggggacac
      481 ctcggtgtcc ctgcgcggac gcatgagggc tgcccgcccg agtccgcggg tagaccgcac
      541 gaggccggcg gcaacgccgg tcctagatgg atggccgtcg ccccgacgac cgcgaggtcc
      601 cggggcacag aacccggcgt acagcccgac tcgtctgcca tggtggcccc ggccagggtt
      661 ttccctggcc ggggccacca tgcgtccgcc cgcgttgccc gcccgtaccc gggcccggca
      721 gtccccctgc tctggccgtg ccggcatccg gtgtcctagt cgctgtgctc cttgcggtgc
      781 cagcgggtcc agacccgggc ggacagccag gtgatggcga cgacgatgac gccggcgatg
      841 acgttctcga tgatgttgtt catgtgggca tgtctcctcc gcgccggtcg gtgtgcgtgc
      901 cgaccgggcg cggcgctgtg ggcagagggg ggttaccggg ccgcgaggcc ctgcggcagg
      961 tgcgggtaac gcatgaagag gcgcgtttcg tcgcgcagcg ggatctcgcg ggcgaagttc
     1021 tcggcgagtt ccgtgcggtg gcggacgggc ttgggtacgt gccggtcggc gcggaagccg
     1081 agcatccggg agaaggcgca ccaggctcgg gagtccgtgc tcgggccggt ggccgcgtgg
     1141 tgggcggcga gcaggtgcgc ggcgagtggg tctccggcgc cggcggcgaa gcgccaccag
     1201 tacatcgcgg attcgcgctt gtcgaggctg tagagcaggc acccgaaggt gcgggcgccg
     1261 gcttcgtcgt agtccgccgc gaatgcggcg agggtgtcga tctctgctga gcgcagcact
     1321 gtgctgcaca gctcggtgac gtagccgaag gcgaggtact ggctcttggc gggatcggag
     1381 gtgttgatcg gtgtcgggcg gcggcgtcgt gcccgtggcc ggcgcggctg cggccgcccg
     1441 tccggccgca gcgtgcgcgg gagggggccg gcggcgggtg cgggcagctg ggtgatctcc
     1501 gtggtctcgc ccgggtaggg gtcgtgcgcg ccggcggccg ggcccgcggg cgcgtactga
     1561 atgcgtgccg gccgccgggc ttcggatgtg atccgtgccg ccaggcgctg cataaagtcc
     1621 tcggtgctgt gctgcaggac gtgcgcgcgg atcgcttcgg cctggcgggt catcagcttc
     1681 atcgcgccct ccgttcccgc tccgtcccgc ggctggtccc cctcggtcgg ctggtccggg
     1741 gtgtgcccgg gtttcccggc gttgcgagcg gtctcttcgt ggacggtccc ggcctgttgg
     1801 ttcaggaggt cttccggcat caggagtccc ctttctcctt aggaagttcc gtgagcatga
     1861 gctcggtcag ctgctgacgg ccccggcacg cggcggtctt cgcggcgctc tgggtgatgc
     1921 cgaggatctc ggcggtctgg gcgtaggaca gcccgatgag gtagtacatc tgtacgcagc
     1981 gggcctgctg cggcgcgatg acttccagtt gctccatggc cctgtcgagc cggtcgtaac
     2041 ggcctagttc cgtcagggcg gaggctgcgg gcatctctgc gacgaggtgt tcgtacttcg
     2101 tgatccgcac gctgctgcgg tagtagtcgg tgatcgcgtc gttgaggatc ttcgtggcga
     2161 gcgcgatggg gttcgaggcc gcgaggatcc gctcgatccg ccggtgcatc gtgaccatgg
     2221 cttccatcag ggcgtcttcg gcgtcgtgca ggttgcgcag gcggtaggcg gctatgcgca
     2281 tgaacgtgtc caggttctcc cggaagaatt cctcgccgcg ggggtcgagg cccggctggc
     2341 cggggtcggg gccgacgagg tcgcgttctt tgccgaacgg atcgttcatc ggcccctccg
     2401 tggtgccggg ctgctgccgg aggccgggag tacggtcggg cgctggtggt ggaccggccg
     2461 gtcgggccga tggccggcct ggtgaccgag ggtggagcgg acctgcgagg cggtgcgggc
     2521 ggcaggccgt acgacggctc cggagcacgc ggtggtcatc cgacagacgc aggccgagcc
     2581 gtgcgtgtac cgggtccggg tgggccccac gaagcctcct tcttgatcca ggatcggagc
     2641 ccggcggcga cggtgccgta cgggcggaac aacggcttgt tctgccttca caccgatccg
     2701 gcacccctct ggagttacaa gccggcgcaa gattttcata cagacagtca tcggttaatc
     2761 acatttagtc ggtctaccag gagtgatgcg gtagttaggt gatccacgtc acacccgcag
     2821 ggagtgccgc acggtcgaag gcccgctggg acgtgaccgg atcgcgcatc ggtgcaaccg
     2881 gtcgcgcagc cgcgcgtgtg gaagccgttg aacgcatgga accgaccaac agggggagtt
     2941 gctcatgtcc cgatggaagg aactgcccgc ggcgctcgac gacagcgaac gtcagctgct
     3001 cgtccagtta cgacgtctga aggaccgcag cggtctgagt ctcgccgccc tcgccaacag
     3061 gaccggctac agccgctctt cgtgggagcg gtacctgaac ggaaagcagc ccgtgccccg
     3121 tgaggcggtc gaagagctgg cccaggtatg cggcacggac ccgacccgcc tcgtggtgct
     3181 gcaccaagtc gccgcacgca cacggaaagg cggcgggccg ggtgagcccg caccgtccgg
     3241 gccgtccacc tctccggcgc cgcgcgagcc ccgtccggcg cgtaccttgc ccatgcgacg
     3301 tacgctggcg gcggcaatcg ccgctgtggc ggtgtccttc ggcgccgggc tgatgacagc
     3361 aggcgcctgg gacgacggcg ctccggtgac gacaaccggc acccgggccg ccaccaccgg
     3421 ctatctgcgc ggccagacgt acagctgcga catccagcgc gggaacgggg aactgcgagc
     3481 cggccacagc gacacccgcg cgatgctcct cgacatcaac agcaccggtt tcgatgtggt
     3541 ggaagcacag tgcctgctcc gcgaacacgg cttcgacccc aaggccttcg acgggctcta
     3601 cgacgagcgg acccaagcgg ccaccaaggc gttccaagcc aagcgcggcc tggtcgcgga
     3661 cgggatcatc ggcccggaca cctgggggga gctgcgccga tgatcaccgg tgccgcgtgc
     3721 gaggaactgg tgaccgagct gcgccgggcg cgggagcgga gcggtttgag catggcggcg
     3781 ctggccgccc gtactccgta cagcaagtcg tcctgggagc ggtacctcaa cgggaagaaa
     3841 cccgtaccgc gtggggcggt cgaggcgctc tgccggatca cgcgggaacc cgccgaaccg
     3901 ctgctcgcgt tgtgggaact cgccgacgcc acctggagcg gccgggggcg gcacccgggc
     3961 ggcgcagtcc cctcggcgcc gtcggtcacc gctccgggcg ggaggcccgc cgcgcgtcgg
     4021 ggacggtggg cagggttcgc cggcgctgcc gtggcgctgt ccctggccgt gctcggcgtg
     4081 tcgatggccg ggacgcggca ggacccgccg cgggccgccg cggagccccc ggtacgtaac
     4141 cccgggtgta ccgcggaggc ttgcgaaggc cggaaccccg tggacatggg atgtggcggc
     4201 agcgggatgg tccagaccct cgccaggcgc accgcttccg aaggccgccg cctggaactg
     4261 cggcacgccg aggtctgtcg cgccctgtgg gtacgggcca ccggcctcga agcgggtgac
     4321 cgggtcgaac tgcgcctgtc cgacgggcgg ttgcagtacg tgacggccga agcaggcccc
     4381 gaagccggga ggtatctgtc gaccccgatg tcctccgaca ccggcacggg cacgacggga
     4441 gtccgcgtgt gcctcaaggc ggcgtcgagc ggccgagagg agtgcttcac cggctgaggg
     4501 catggcgggc agcccctccc cgtctcccca cgtcccatcc cgcactccgt cccagcaggt
     4561 cagggcgtgg gacgtcccgt gtgctcccac accggcggcc ggctgtggcc ccccgtggac
     4621 cgggctgggc atcgttgcac cacgccagga ccacggcccg ggaagcggga cccaccgggg
     4681 gcacgccgga ccgtggccgg agaggaacac agccatgaac acgcgtacga agctcgcggc
     4741 gctcgcactc accgccgggg tcgtcacggc cacgggcggc gccacagcgc ccgcggccgt
     4801 ggccctgacc acgccggcgg cccactccgt cgtccagccg gccgcggcca cgccggccga
     4861 caacggcgac gtccgggcgg cgggttccgg gtcggccgac cggacgctga ggaccagcaa
     4921 cggagccggt tccgttcgcg tcaagtggac ctggcacagc agcgcgaacg gcaagagcta
     4981 ctacggcagc ttctggggga cgttctacga ccacgccccc aaggacaaga agtacgtgct
     5041 gctccaggcc aagtggcagg gcaagggctg gacgaccata cgcaccgccg cgaagggcgg
     5101 caccttcagc ggcgactaca gcggcctcaa gggcctgaac ttcagggcct gcctccaggg
     5161 cggcaagtgc ggcgcacccg cgtggtgacc tcccggggcc cacaggtctg accccgtacc
     5221 tctgatcgct cgccgacctg gcccgcctgc cccggcagtg gtttcgcact gccggggccg
     5281 ggcgccggct ggacacggat tccacgggcc gtaccagtcg gccggcccca ccgccgaact
     5341 gaaaatcccg gccggggcgg ggataatcat gttcggggcc aggtctggca accggccgca
     5401 gggagcgaca ttgatccgtg ttcttctcgt cgggaagacc cgcctcgtgc ggggggcgct
     5461 cgccgctctc ctctcccgcg aggaggacat cgatgtcgtc gccgaggcgg agggggacgg
     5521 cgaactcgtc gcgcgggcga tgctgtgccg gccggacgtg gcggtgatcg acgtcgactg
     5581 caaagagggc gaggagttcg ccgcgaaggg agagctgacg gcgcagctgc cggactgccg
     5641 gatgctgctg atgatggcct cgccgacacc cgaacgtctc cgccggatgc tcgacctgca
     5701 cgccgcgggt gtcatcagta cgaacgcccc ggcggaccgc ctggtccacg gcgtacgcaa
     5761 gctggtgcgg gggcagcggt tcatcgaccc ggagttcgcg ctggtcgcgc tggacgcggg
     5821 ggacaatccg ctgactccgc gcgaggtgga ggtgctccgg atggccgcgg acggcacgcc
     5881 cacgggggag atcgcccagc ggctgtcgct gtccgtggcc acggtccgca accacctgtc
     5941 ggcgatcacc aggaaagccg gggcgcggaa caggatcgac gcgatccgga tagcgcggga
     6001 gtcgggctgg gtgtgaccgc cgacgggtcc gccccgtccc agtggccgac gaggtcccgg
     6061 tagagcgcgg agccggccat cagctcgtcg tgggtgccga ggctgacccg cgtaccgtcc
     6121 atgaccagga cccggtctgc ccgcagcgcg gagctgatgc ggtgggcgac gaccatcagg
     6181 gtgccggggc cgcgggcgaa ggcctcttcg gcgaccgcct cggcgaccgg gtcgaggtgg
     6241 cacgtcgcct cgtccagcag ggccagtcgc ggcgccggga ggagggcccg ggccagggcg
     6301 atgagctgac gctcgccggc cgacagctcc cgcgggtcca gcggcgtgtc gtagccgccc
     6361 agtttctcca cgagcgctgc ggccccgacg gcgcggacgg ccgactccac ctccgcgggg
     6421 gcggcgccgg gggcgaggta ggtgaggttc tcccggaggg tgccggcgaa gacgtacgcc
     6481 tcctgcggga tcagcacgcg gtgccgggcc aggtcctcgc cgtccagcgc caggaccggt
     6541 acgccgccga ggcggatctg cccggcctgc ggggcgagga cccccgcggt cagcgcggcg
     6601 agggtggact ttccggcgcc gctcgggccg accacggcga ggtgttcgcc ggggcgcagg
     6661 tccaggtcga gatcctggac caccggctcg gcggaccggg cgtacctgaa ggtgaccccg
     6721 tggagctcga cgcgggagtc gcgcgggcgc gccgggcgcg ccgggtgcgc cgggtgcgac
     6781 gggggagcgc ccggtggcgg tacgggtggg ctccggtcgg gctcaggggc gcgctccggg
     6841 acggcgccgg gctcggcccc gggctcggcc ccgggctcgg gctcgggctc gggctccggc
     6901 cctgggccgg acggcggcag ggccggagcg ggcgcgccgg gggcgacctc cgcgatccgg
     6961 ccgatggtca ccagcagcca cagcccgctg ctcccgagtt cctggacgaa gttctgcagg
     7021 gccgggctca ggctctgcga cacgtaggtg agcgctccca ggatcgctcc cgccgtcacg
     7081 ccgttgcgta cgagccaggg cgccccggcc aggatgagga cgagcggtac ccagccgccg
     7141 atgcccaggg cggcggtccg cagcgcggtg agccgggcga gggccctggt ggcccgggcc
     7201 gcgtcgtcga cctgggcccc ggtccgtgcg cggacgcgct cgtcggcacc gcaggcgatc
     7261 acgtcccgca gcccgccggt caccgcgctc gcggtctccg agatgcgctc gttggccagg
     7321 atgacggccc gctgcctcgc gaccatcgcc cggagtgccg ccaggaacag cccgagcccg
     7381 aggaggagcg gcggcaggac caggacgagg aaggcggggt ccagggtcgc caggcccagc
     7441 agcacggtca ccgccgtgac caggaagccc tggacgaaca tcacgaccgc cccgtacgcc
     7501 tcacgggcga tctccacgtg ctcggtcagg cgggccacgc cggcggtgtc ggcggccccg
     7561 cccagccgcg tcgagcggtc cagcgtgccg gtggtcacga gggtgaccag ctcgtcccgg
     7621 aacggttcga tcagcgcggc gagtcccagg acggcgtgcc gggtccccca cgccccgacg
     7681 atgaaggcgc ccgccagcag ccccagccag gcgaagccga caccgggccg gccggcgagg
     7741 aagccctggt cgaccgcgcg ggccacggcg aggccggaca ggaaggccgg cacggcctgc
     7801 accagcgacc agcccgtcag ccgcaggtac tcgcggcggc gccggcggag tgaggcgcgc
     7861 aggaggtcgc cgggccgccc cttcaccgcg tacctcccac gtccgcggtc tgcggcaccc
     7921 gcccggcagc ggcgtccgcc tggaacgcgg cccggtagtc ggggtccgcc cacaggtccc
     7981 ggtgccgccc ccgcgcgcga acgccgccgt ccgcgagcca gatcaccagt tcggcccggg
     8041 cggcggtgga ggcccggtgc gtgacgatga gccgggtacg gtcggcgagg gcgccggtca
     8101 gcacctggct gatgtggtgc tcggtcacgg tgtcgaggct ggcggcgacg tcgtcgagga
     8161 cgagcacccg cccggcctgg gtgaacgccc gggcgagccc cacgcgttgc gcctccccgc
     8221 cggagatcgg ggcgtcggcg agccgggtgt cgtagccggc gggcatgtgc cggatgaacg
     8281 cgtccgcccg cgcggcggtg gcgtgcgcca ccagctcctc cgtggccggg gtacgagggc
     8341 cgaagccgat cgcgtcggcg aaggtctcac ccagcagtac ggggcgttcg aagccgtacc
     8401 ccaccgcccg ccgcagctca ccccggtcca cgcggcgcag cggcacgccg tccagcagca
     8461 cctcgccctc gtcggggtcg acgagacgcc cggccagcgc ggccagcagc gacttgcccg
     8521 accccgaacg ccccacgacg gcgaccaggg cgcctcccgg cacggtcagg tcgaggtcct
     8581 ccaggacggt gtcgcccccc gcgcgtaccg tgacgccccg gaactccagc cgcccccggc
     8641 cgtcgggcag gtgctcggag ccgtactcca cgggcggttc ggcgaacacc tcggcgagcc
     8701 gcccggccgt cgcacgtgcc tggacgagtt gattgagcgt acccaccacc gagccgatgc
     8761 cggtggccat gaccacgtac tgactggccg cgagcacctc tccgggcgtg atgcgcccgc
     8821 gggcgagctc cagaccggcc acggcgatca cggcgaccat gaccagcggg acgacgagat
     8881 cctcccgggc cgacatccgg gcgagggaac gccacatccc catgccgtgc cggtgcagct
     8941 ccggcagcgg ggcgagcacg cggcgcgcct cgcggtccac ggtcttcgcc gcggcgatcg
     9001 tgcggcttcc ggtcagggcg tcggtgagcc gtgccgcgat ccttccctgc gtgtcgaagt
     9061 agcgttcgtt gaggtcggag atgtcgcgga tgaaggcgcg gaccagaggc gccaggacgg
     9121 gcagaccgac gaggaaggtg aggcagagcc acgggtcgat cagcgccagg gcgacgatgg
     9181 cgccgatcgg gggaacgaga ttcatgaagg cccacaccac gcccgatgcg acccgccccg
     9241 tctcggaggt gttgcccacg agccggctca ccaggtcgcc ggagtcgaac cgtcgggtgg
     9301 cgcgggtgcc cagcgcgagg atgtgccgca gcagcgtgtg gcgcagccac gcggtggagc
     9361 gggcctcggt cacctcgccc acgtagtcgt ccagcgcgtc ggcggccacc aggacgaaga
     9421 tcagcgcggc gctgagggcg agccagcggg ccgcgtcctg gtcgccgagc acggcgtcga
     9481 gggtgcggcc catgacggcg ggcagcacga ctccggcacc gctgatcagc aacgacgtga
     9541 ccagcatgac ccccagccag gggccgcccc gtcgggctgc cgccagcagc aggcggtccg
     9601 cggcgcgtcg gtccacgggc ttctcctccc ggtcgtctgc cgtcgtgcga gctacgggcc
     9661 gccgcgatcc tcgcggggac gggttgcccg gtggtcgcgg ggccggtcgc gggtcctccg
     9721 cggaaccggt cacgcggtgc tcacggaacc ggtcacgcgg tgctcacgga accggtcacg
     9781 cggtgctcac ggggccggtc acgcggtgct cacggggccg gtacggcggg gacgcccgga
     9841 ggcgtccccg cccctttcgg tcacagcctc acgcgcacct tgatgagctt gccgactttc
     9901 accctgacgg cgatgccgcc acggcagctg gccgacgagt tcgagccgtg cgccgcggtt
     9961 tccgcgtccg gcatgtcgag gccttgcaga tcgaggagtg tcatgtgatg tcacctccct
    10021 tctttgcgag aaccggtggt tggactgtgt gccgtgttcc gtcggccgac ggagtgccca
    10081 ggaacggcag gtgcacggga tggtggtgga gggcggcacc gagggcgagc agcacgccgg
    10141 cgctgccggt ggccaggtcc atggagagcc gcatgagctc ctcaccggga aagaccaggt
    10201 ggccccggag catgagggcc tgccgcgaaa ggtggcgtac atgtgcggcg accagggggt
    10261 cccgcccggc ggccgtgccg gcgggatgcg cgcggctgag gtaaaggatc agcccggccg
    10321 tgccgcggaa gagcccgggc tggacggaga actgcaccgc cgccgccctg cggatctcgg
    10381 cggccgccgc ctcgaaccgg tcgtcgccgt ggtgggtgag gtactcgtcg aggacgaggc
    10441 cgatcccggc gctgccctcg gcgaggtacg gcacggtccg ccacccttcg tcgacctgca
    10501 tcccgccgtt cttgcggacg acgcagcggc gcaggtcccg gcggagggcc gtgccggcca
    10561 ggtcgaggaa cgcggggtcg ccggtgtgct cgtacagccg gaggaacagc agggcgggcc
    10621 ccgaggagcc gcgcatcagc cccgcgtacg ggtacttgcc gccactggtc tccggtacgc
    10681 cgtcggccgg gccgagccgg tcggcgacgg actgcgcgac gttcatggcg gcgtcgtgga
    10741 acgcgggttc gccggtgacc gccgcgaagt gctggaggtt caggccgatg cccgcgagcc
    10801 ctccgtgcag gtcgagcccc agctcctgcc actggtcgtc gcccatgcag atgtcgagga
    10861 ccttcatggc cgcgtcgcgg tggccgaggt ggtcgagtac gtgggcgacg ccgtgcaggc
    10921 cgtcgtagaa cccgccgcgg gtgccctcct ccgcgcgcac ggcccggtgg accagccact
    10981 cctcgtaccg cgggtggcgc ccggcgccgg tcacgtccag cgcgtacagc actccggccg
    11041 cgccgtacgc gaggcccagg cccccgcccg gggccctgaa ctgctcgatg tcgccgggga
    11101 agagccggtc gtcgcgccgg ggggtggcgg cggccaggat ggcggcggtc atggagctcc
    11161 gggcgcgcag ccagccgtcg tggtcggctt ccagccgcgg ctcggtaccg gcagcaggcg
    11221 tacggccgtc gcttcccgtg atgacccgca ccgcctcgtc caggaacgcg cggggtaccg
    11281 ggaacgaccg gcgggcctcc cgggcgagct gtgccgcctt ggccctgtcc agctcgatga
    11341 gctgtgtcag cggcatgaaa agggacaggc gcaggcaggc cagggcgtac cggtcgatgg
    11401 cgaagccggt cagttccccg ggcgcctgga acccgggagc ggccagggtc tggggccgtt
    11461 cctccgccgc gtccgccgcg ccctcgaagt cgatcagcac gacccggccg tcggggcgta
    11521 ccaggatgtt ggacgggtgg aggtcaccga ggaccaggcc ccggtcgtgc accgcggcga
    11581 ccgaccgttc cacccggccc accaggtcga cggcccacga ggtgtaggcg acggccgccg
    11641 tgtcgtccgt ctggtccggc ccgtccggct ccaccgacga cagggggtag cgctcgcgga
    11701 agaggtccgt gagcggctgc ccctcgacga actcctcggc gaggaagtgg tggtccccca
    11761 ggacgaagtg gtcgtgcagc gccggtacgc agtcgaggcc gcgcagccgt tccagcgtct
    11821 cccgctcgcg gtgcagcctg ctgaccgcgt ccgcgccgtc cggtgtgagc cccgcgtacg
    11881 gccgcgcctc cttgaggacg acgcgttccc cggtccgggt gtcctgggcg gcgtacaggc
    11941 ctccgccgtt ggagaagtgc agggcctttt cgatccggta cggcaggtcg gcgacggtcg
    12001 tcccggcccg tgcggcgagg tggggctcca ggaagccggg cagcgtcacc cactcgggca
    12061 cctcgaacac cggcttgcgc aggtcgggca cgagccggcc ggacgcgtcc tcgacggcca
    12121 gcaccgtctc gcccgtggcg ggggagacgc agtaccgccg ggcgaagccg ccgtacctga
    12181 cgtagagcgg ccctgacgcc cagcgcagat cgctgagaat gtacggcccg ggccggccgt
    12241 gcaggacgcc gtccaggtcg gtgaggacgt ctttgagccg ggcctcgtcg gccgggtaga
    12301 tcgtcacgaa tttcccgctc gcgccccggg gcgcgtattt gatgttggcg ttgagcagtg
    12361 cgtcgagccc ggggcggaat ttgaaggaga tccgccgggt gatgcagtag tcccacaccg
    12421 cgccgaggat ctcctccgcg ttgtcgaggc acgccgatac atggaccttc cacccctgcg
    12481 ggggcagctc ggcgccgtcg gggtggagga ccacccagtc gtcgaggtcc tcacgcaccc
    12541 atgtatcggg aaccggacac cgggtctgct cgaagtcgct gtcgctgtcg ctgtcgctgt
    12601 cgctgtcgct gtcggcggcg gtgtcgccgg cgcgtgcggg ggtgtcgtag aagagggggt
    12661 ccgtgaggca aaaggcctcg taacgcatgt ccacgggagt ctccgctcgt gggctgggat
    12721 gcccgtatcc gcccgggatc attagcgagg attgcagagc ggaccggccg cggaacacca
    12781 ctgttcatca cgcgtacggt gggagaagtg acccgcggga taggagaaac tcccgtttca
    12841 ccgtcgaata ccaggagatc gcggaggttg tctcgcacac cggtcggtcg gcaatcggca
    12901 ttcgaggggg catgggcagt cccggcggca tccggcgggg gtgagccgaa cagcgagagc
    12961 ggtaccgcac gggcggcgtc ggtgatgtca cgctgaagaa gaagctcgtc gaggcctcag
    13021 gcggtgccgg gcgtcggccc ccggcactcg ggcgttcact cgttcacccg tttggatagg
    13081 gtgcccggat gatattcggg aaggacgggt tcctgcgggc cgtcgacgcg ttcgagacgg
    13141 ccgtacgggc ccatgacgcg gacggtgccg aaggcgccta cgcggggctg cacaagacgt
    13201 acgagcaggc ccgggacgac gaattcctgg ccgccgggcc ccggttggcc gagctgctcg
    13261 ccgaagtgcc gcccgggcca cgggccgtgg tcgccgtgat caccggggcg tgtgtcgagc
    13321 gcggcgccga cccggtggcg tgcgcgccgg gtgtgctggg cggcgtacgg ggcgcgttgc
    13381 aggccgccga ggcgttctgc gagcggtggg cggccaccgg cggcggggac ctgccgcagc
    13441 ccgaggccga cgagctgacc gacgagatcg tcgaccggac cggtttcgag gccgcgatgg
    13501 gctggtggtc gctgccgcag tgggagatgg ccgcgctcgc gatgctgaac tccaaggcgg
    13561 tacgtcagca ggtgcccggc aaggccgagt tgctggcgct cgcggagcgc gtccaggacg
    13621 cctccggcca ccccttcaag tgcctggtgt acgcgctgcg cgtcctcgac gacgagccgc
    13681 tggtcgtcct gcaccgggag acccgcaccg gatacgcgat gcggatgacc ggcatcggcg
    13741 acaacttcca gctccacacc ctgctggccg gcgcgctcat cggcggcctg cacctgccgg
    13801 gcgacgcgcc ctccgcgcag gaggtggccg tgtgccggga cgcccccggg caggtcgaca
    13861 cggccggctc gttcaacctg gtcggcgcgg acggcggctg gatctggaac gagggcaccc
    13921 cttccgacat cccggtcgtc gacggcgccc gcctgctggt cctggacccg ccgccgtacc
    13981 ggcggggctg ggcggcgggg cggttcttcc ccgacatgac cggcgacctg gtgctggagc
    14041 gggtgctggg cgccgaggag acggagcgct ggttccgcca cgtcgccgag gcgaaggact
    14101 gacacgccac gggcggcgca aggtccacgg ggagcgtggt acgcgggtgt acgggtgagg
    14161 ctcccccgta cacccgcgta ccggtacccg taccgaagga gacagcatga ccgtccccgt
    14221 ggaccagctc accgacccgg ccgtacgcgc cttcgtcggc gcggtcaacg ccagcgacca
    14281 gcaggcgttc tacgccgcgc tcacgccggg cgccaccatg tccgacgacg gctccgaccg
    14341 ggacctccgg cagtgggccg agcgggagat cttctccgtc aacgggcaca tggacgtcga
    14401 gtcggagcag gccgacggcc tctccctcat cgcccgctac cgcaacgaca cctggggcga
    14461 gatgcgcacg gcgtggcggt tcgtggtgga gggcggaaag gtgagccgct tcgagacggg
    14521 ccaggcgtag ggcagggcgc ggagcgggcc gggcgtgggg ccggcgtggg gccgggcgtg
    14581 gccgggcggg atcagccgcg gccgatgtac ggcatcgtcg tggccagcac cgtggcgaac
    14641 tggacgttgg cctccagcgg cagggccgcc atgtgggcga ccgtgcgggc cacgtcggcc
    14701 gcgtccatga ccggctcgac cgccagttgg ccgttggcct ggaggatgcc ggtctccatg
    14761 cgctgcgtca tgtccgtcgc cgcgttaccg atgtcgatct ggccgcacgc gatgcggtag
    14821 gggcggccgt ccagggacag ggacttcgtc aggccggtca tggcgtgctt ggtggccgtg
    14881 tacgcggtcg agtgcgggcg cggcacgtgc gccgagatgg agccgttgtt gatgatgcgg
    14941 ccaccctgcg gcgactggtc cttcatctgc cggtacgccg cctgcgcgca caggaacgcg
    15001 ccggtcaggt tgacgtcgac gaccgagcgc cacgtctcgt actccaggtc ctcgaccggc
    15061 gtgccgcccc cggcgaagct gcccgcgttg ttgaacagca ggtccacccg gccgaagcgg
    15121 tcccgtacgg ccgcgaacag ggccgtcacc gcgtccggcg acgtgacgtc ggtcggcacg
    15181 cacagggcgt ccaccccggc gagcgccgcc gtctcctcca ggggctcggc ccggcggccg
    15241 gccagggcca gggcccagcc gtcctccgcc agggcgagcg ccacgctccg gccgatgccc
    15301 gagccggccc ccgtcaccac cgcgatcccg tgtactgcgc tcatgaggcc gcagcgtacg
    15361 ggagagtccg gcacgcggaa ctcatgtggc cgacatatgg atgttgtgta cccgacaacc
    15421 ggtgctactg agatgcccct gacagccacc gccaggggag gggtccatga cacccgcaga
    15481 ccggtccagc gcccagcacg cacccgaact acgcgccgcc gcccgccact tcggccgccg
    15541 cggcttcctc accgtcaccg gggccgccgc cgccctcgcc ttctcggtga acctgccggg
    15601 caccgcccac gccgccgagg ccgacccccg gaagatcacc gaggacccgt tcaccctcgg
    15661 cgtggcctcc ggcgaccccc tgcccggctc cgtcctgctc tggacgcgcc tcgcgccccg
    15721 cccctacgag cccggcagcg gcatgccccg ggcccgcgtc cgggtccact gggagctcgc
    15781 ccacgacgcc cggttcgccc ggatcgccag acgcgggcag gccaccgccc acccggaact
    15841 cgaccacagc gtccacgtgg aggtgcccgg cctcggcacg gaccgcgtct actactaccg
    15901 cttccgcgcc ggcacctgga tcagcccgac gggccgcacc cgcaccgcgc cccaccccgg
    15961 cgcccgcgcc ggcgagctga aactggccgc cgtctcctgc caggcgtacc acgacggcta
    16021 cttcacggcc taccggcacc tcgccgacga ggacctggac gccgtcttcc acctcggcga
    16081 ctacctgtac gagtacgccg tgggcgccac cggcggcgcc cgcaactaca ccgaccggca
    16141 gctccccgcc cacttcaacc gcgagaccat caccctggag gactaccggc tgcgctacgg
    16201 cctctacaag tccgacccgg acctgaaggc cgcgcacgcc gcgcacgcgt tcgtcgtcac
    16261 ctgggacgac cacgagacgg agaacaacta cgccggcggt atcccggaga acggcgtacc
    16321 gcccgaggag ttcctgctgc gccgcgccgc cgcgtaccgc gcgtactggg agaaccagcc
    16381 gctgcgcgcc ccgcagcggc cgaccggccc ggacatgcgg ctgtaccggc ggctgcgctt
    16441 cgggcggctc gcgcagttcg acatcctcga cacccgccag taccgctcca accaggccta
    16501 cggcgacggc tggcagaccc ccggcccgga gtcggaggac ccctcgcgca ccatgaccgg
    16561 cgccgagcag gagcggtggc tgctcgacgg gtggcaggag tcggacgcgg tgtggaacgt
    16621 cgtaccgcag caggtcacct tcgcccagcg gcgcaacgtc cccaccccgg acttcaagct
    16681 gtccatggac gcctgggacg gctaccccgc ctcgcgccgg cgcgtcatgg acggcgcggc
    16741 ggcggccggg atcgagaacc tcgtcgtcct gacgggcgat gtccacgtcg ggtacgcctt
    16801 cgacctcaag gccgacttcg acgacccgga gtcgcggacc gtcggcaccg agatcgtcgc
    16861 cacgtccatc gcgagcggca aggacggcgc cgaccggccc gccaactggg acaacctcac
    16921 ccgcgccaac ccgcacctga agtactacaa cgggcggcgc ggctatgtga ccgtcaccct
    16981 gaccggcgag cgggcgcgcg ccgactaccg gacggtgtcc catgtgacga cgcccggcgc
    17041 gcccgtcacc acggccgcgt cgttcgtgac ggaggcgggc gacccgggcc tcaagccggt
    17101 gtgacccggg cctcggcggc gtccagccct ccccccaatt gaggtttcaa caattgttgg
    17161 gtagctgaga gcatggggcc ggacctcacg agggagatga gatgccggaa agcggcccga
    17221 gtacgccagg acacataccg accgagcgcc cgaaggccgc cattccggcc cccaccggag
    17281 ccgacgaccc cgccggcccc ggcaccgggg ccggtgaccc tcctggccct ggcgccggcc
    17341 ctggcaccga caccggcacc ggggctcccg ctgccgcccc gcccgccgcc gagggcacgg
    17401 gccccgtcgc cgcgcggcgc gtggggctgc tcgtgacgct cgtcctcggt gggctcaccg
    17461 cgctgccgcc gctgtccatg gacatgtacc tcccggccct gccggaggtc acccaggccc
    17521 tgcacgcgcc cgccgccacc gtccagctga ccctcaccgc ctgtctcgcc ggcatggcgc
    17581 tcggccagct cgtcgtcggc ccgatgagcg acaagtgggg gcgccgccga ccgctgctcg
    17641 tcggcatgct gctctacatc gcggccaccg ccgtctgcgc cctggcgccg agccccgaac
    17701 tgctcatcgc cttccggctg ctccagggcc tcgcgggcgc ggcgggcatc gtgatcgccc
    17761 gggccgtggt gcgtgatctg tacgacggcg tcgagatggc ccggttcttc tccaccctca
    17821 tgctgatctc cggagccgcc ccgatcgtcg ccccgctcat cggcggccag atcctccgga
    17881 tcaccgactg gcgcggggtc ttccacgtcc tcaccctggt cggcgtcctg ctcaccctcg
    17941 tcgtgtggaa gtggctcggc gagacgctgc cgcgcgccaa gcggcacagc ggcggggtcg
    18001 gcgaggcgct gcgcaccatg cgcgggctgc tcgccgaccg ggtgttctcc ggctacatgc
    18061 tggccggcgg tctcgccttc gccgccctct tcgcgtacat atcggccagt ccctttgttg
    18121 tgcaggagat ttacggggct tcgccgcaga ccttcagcct gctgttcggc atcaactccg
    18181 tcgggctcgt cgcggtcggc cagatcaacg gcaagctcct ggtgggccgg gtgagcatgg
    18241 acaaggtgct cggattcggc ctggtggtga tcgccctggc ggccggtgcg ctgctgctga
    18301 tgaccagcgg ggtcttcggc cacgtggggc tcgtgcccgt cgcggccggg ctgttcgtcc
    18361 tgatgtcggc catgggcgtg acgctgccca acaccaacgc ccaggctctg atgcgcactc
    18421 cgcacgcggc cggttcggcc tccgcgctgc tgggtacgtc gtcgttcctg gtcggtgcgg
    18481 tcgcctcacc gctcgtcggc atcgcgggcg aggcgacggc ggtgccgatg gccgtggtcc
    18541 agctggtgtg cgcgctgggc gccgtcgcct gcttcatggg cttgtgccgt ccgtggcagg
    18601 accgtcaggc ggttcgcgcg taaccggtca ggtggacgcg gtcccgcgcg tccgtccagc
    18661 ggtagacgcc caccccggcc acctccgccg ccggcagccg cacgctcggc gccagcgcct
    18721 ggggcacgcc ggtcgccagg tccaccgcca ccgggctgcc cccgccggcc agggcgtccg
    18781 ccacgctgcg ggcaccgctc gcgccgtacg ccacgccccc gtccgtgacg gtggtcagcg
    18841 tcagcggcgt ggaaccgtcc gcctcctcga agcagcggcc ggtccgcgcg tccaggtcga
    18901 aggcgaggct cccggcgatc aggtaccggc cgcccggcga gaccaccgcc tgcgggtact
    18961 cgcccggttc gatcgccggc ctgcggcact ccgccttcac cagcggcctg cccgtgcgtg
    19021 cctcgtggac cgcccagatg tcgtgcgtgg ccgcccgcgc cgcgcccttc ttgtgctgcc
    19081 accgcgccag cacgtgcccg gacgtcagcg agccgggcac cccgctcgcc gggtcggcgc
    19141 cggccggggc ccggtcgcgg ctgaaccagc cgcccggcac ccagaagccc cgcgcaccgc
    19201 tcaccagcag gcccttggac gtcaccccgc gcacggcggt cagccgccgg cactccgcgc
    19261 agcccttggg gtggccgagg cgctgcggcg gcaccgtgct cacctcgccg gtgtccggtg
    19321 cgacgaccgc gctcctcgtc cgcccgtcgc tgatcagcac gcccggtccg gtgccggtca
    19381 ctatcggcac gtccgcccac gggacctcca cccgctgccg ggtgccgtcg gccgcgtcgt
    19441 acaggtcgag cgacacgaag ctgccggccg tggtgagcgg gtcgtcgccg gtccttccgt
    19501 acgaccaggt cacgaagaac cgccggccct ccttctccag cgccagcagg ccgggaaagc
    19561 tctccgggtc gccgagcggc cgccagggcc ggcccgccca gccgtggcgg ccggtgcgcg
    19621 cgtcgagggt gcggagacgg aaccgggtgt cgtcgacccg ctccaggtac gcgatcactc
    19681 cggtggtgcg ggcgatgacg tactcggggg agacgccggt gatgtcccag ccccgggagg
    19741 tgtcgtacgc gtcggggacg gtgagccggg tcacgggcgc ggcgccggct ttcgcgggcg
    19801 gcaccgaggg gcgctggtcg ccggttccgc aggtggcgag caggagcagc agggccagga
    19861 cggccacgcc ggccaccagg gccatgcgca cgatcctctg tctcactggt ccccccaccg
    19921 gccgacggcg gccagcgtag caactacggc ccgccaccga gcagttacgc gcccctgccc
    19981 aggccccgcc caccgccccc gtcgcccacc gcccccgccg acctgcgcgc ccgcccgcgc
    20041 cgcatcgcca aacccgccgc cccgccgccc cgcccaccgc gcccgcccgc gccgcgtcgc
    20101 ccgccccgcc cgcgccgcac cgcgcatcgt gcccgtcgct caccgtgccc ggagggggcc
    20161 gtgtgccggg cgcctacgat ggatcggtga acgtctccct ctccaccgcg gacgccctgc
    20221 gtggcgccct cgccgggctg ctcgacgggc tgccgccgac gcaggcggca caggcagtcg
    20281 accggctgat cgcccactac cgcgggacgg tcccgaccgg cgcgcccgtg ctgcgcgacc
    20341 ggtccgacgt cgccgcctac gccgcgtacc ggatgcccgc gacgttcgag gcggtacggg
    20401 cggcgctggc ggcgctgcgg gacgcggcgc cggagtgggt gccgggcacg cacaccgaca
    20461 tcggcggcgg gacgggtgcg gcgagctggg cggtcgccga ggcgtgggac gcggcggcgc
    20521 gcaccaccgt gctggactgg gccgagccgg cgctggcgct gggccgcgag ctggccgccg
    20581 cgtcggggat cccgtccctg gaggccaccg cgtggcagcg cgcgcgtatc agcgcggcgc
    20641 tccgcgtcga gagcaccgat ctcgtcaccg tgtcgtacgt cctcaacgaa ctcaccgagc
    20701 aggaccgcac ctccgtcgtc accgaggccg cccgggccgc gcaggccgtc gtgatcgtcg
    20761 aacccggtac ccccggcggc tacgcccgga tcatcgccgc ccgcgacctg ctgatcgcgg
    20821 ccggcctgac gatcgccgcg ccctgcccgc acagcggcgc ctgccccatc gagccgggca
    20881 ccgactggtg ccacttcgcg gcccgggtca gccgctcctc cctccaccgg caggtgaagg
    20941 gcggctcact ggcgtacgag gacgagaagt tcgcctatgt cgtggcgacc cggttccccg
    21001 tggcccccgc caccgcgcgg gtgacccgca agccccagat ccgcaagggt caggtcctgc
    21061 tggacctgtg caccgaggac gacgggctgc gccgcgacac ggtgaccaag cggcacggca
    21121 cgctctacaa ggcggcccgc gacgccgcct ggggggacga gtggccgccc cgctgacggg
    21181 ctgacggggt gacagtgggc gaccacgcgg gtgacgtcgt gcccgtggca attgccctgg
    21241 gccccctcgc ggagttgagg tgggctcgtt ccagccacct cactccctgg aggttccctt
    21301 gctgcgcacc cgctcgcgcc gtttcaccgc ctgcgtgctg accgccgcgt ccgcgatgct
    21361 cgccaccacc gccctgacct tcaccgccga cgcggcgccc aagcccaccc cgaaggacgc
    21421 gccgaaggac tccgtgaagg tgctcgactg gctggcggac aagcagtccg acaccaagcc
    21481 ggaccgcctg cgcgtcggca gcgagtggac ggcccacgcc cacctctaca cccacaagaa
    21541 gggcaggccc ggcaagaaga tcggtgacgc ctcctcgcgc tgcagcgtcg tcgacctcac
    21601 ccgccacggg tacgtcgccc tgtgccaccg cgtactgcgc accgacgacg gcagcatcag
    21661 cctgagcgac tccatcgacc gcttcggccg ctatccgcac ggcgggcgct cggctgtcac
    21721 cggcggcacg gggaagtacg tggacgccga gggcgaggcc gagatcacct tcatcgacgg
    21781 cgacctcgcc cggttccgca tcctgctcga cgactgatcg cgcgggatcc cgcgcacggg
    21841 ggccggtccc gcccggggcc ggccccctgc cgtggagtca ccggtcaggc gcgcagttcc
    21901 tgcgtacagc acttcacgct gccgccgccc ttgagcagtt cgcccaggtc catgccgatc
    21961 ggctcgaagc cgcgctcgcg cagtggccgg aacagcccca ccgcggcctg tggcagcagg
    22021 acgtgtctgc cgtcgctcac cgcgttcagc ccgagcgccg ccgcgtcgtc ctcctcggcg
    22081 atcagcgcgc cggggaacag ccggcgcagc accgagcggc tgccggggga gaacgcgccg
    22141 gggtagtaca tgatctcgtc ggccgcgtcg tccaggacgc acagggccgt atccaggtgg
    22201 tagtagcggg ggtccaccag gtccaggccg atcaccggcc gtccgaagaa ctcctgcgcc
    22261 tcgtcgtgcg acaggggact ggagcggaaa ccgcgcccgg ccaggatgta cgaggcggtg
    22321 acggcgaagt cgccctcgcc ctcgttgaca tggtcgggtt cgcggacgtc ggtgaagccg
    22381 tgggcccgga accacgcgcg gtggacggcg gcctcggcgg cgcgttcggc gtgcgcgaac
    22441 cgggcgccga gcacccggcc gtcgatgacg gtggcgccgt tggcggcgaa caccatgtcg
    22501 ggcaggtcga ttcggggctc cagcagctcg acggtgtggc cgagcgccag gtaccggtcg
    22561 cgcaggtctt cccattgggt gagggcgagc ggcaggtcga ccggtttcgc ggggtccatc
    22621 caggggttga tggagtacgt caccttgaag tgcgcgggtg ggcacatcag gtagcggcga
    22681 ggtgatgc
//
