LOCUS       NZ_LIVZ01000013        28361 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0107 scaffold13, whole genome shotgun sequence.
ACCESSION   NZ_LIVZ01000013
VERSION     NZ_LIVZ01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0107
  ORGANISM  Streptomyces sp. TSRI0107
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 297943)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297943)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905845.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,745
            CDSs (total)                      :: 7,667
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 200
            CDSs (without protein)            :: 200
            Pseudo Genes (ambiguous residues) :: 0 of 200
            Pseudo Genes (frameshifted)       :: 85 of 200
            Pseudo Genes (incomplete)         :: 158 of 200
            Pseudo Genes (internal stop)      :: 13 of 200
            Pseudo Genes (multiple problems)  :: 51 of 200
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:19:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 267260
            Orig. end                         :: 295621
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVZ01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28361
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="crocagin"
                     /region_number="3"
                     /rules="(PhyH and Carbam_trans_N)"
                     /tool="antismash"
     cand_cluster    1..28361
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PhyH and Carbam_trans_N)"
                     /kind="single"
                     /product="crocagin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28361
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18361](+)"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18361
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
     misc_feature    1132..1147
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.78"
                     /tool="antismash"
     misc_feature    complement(1650..1660)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(1697..3562)
                     /locus_tag="AMK31_RS31970"
                     /old_locus_tag="AMK31_31435"
     CDS             complement(1697..3562)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566578.1"
                     /locus_tag="AMK31_RS31970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31435"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_073944239.1"
                     /sec_met_domain="Pkinase (E-value: 1.6e-46, bitscore:
                     152.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEGEPGRRVIDGRFELEARLGGGGMGTVWRARDVVLDRAVALKE
                     VRPPDPGLAEYDPEAAALLRARVLREARALARVEHPNVVTIHHVVDGAGYPYPWLVMEL
                     VTGGSLADRLARGPMEPREVARLSREVLGALRAAHAVGIQHRDVKPANVLLRTDGRPVL
                     TDFGIAAIRESTVLTATGSIIGTPDYMAPERVSGGEGGPESDLWSLAMMLYVAVEGHHP
                     LRRGSTLATLAAVLNEELPPPRQAGVLGPLLDAALTKDPARRPDAATVDAMLAEAAEGP
                     TPDSAADRTGTTSFRLAPPDASARRPAGPVTAGAAPSSGSLPHTAPTPTAPPESSSQSS
                     PYAPHAQHTPNPPFPSAHSVRDTPPLGQPQHHPLPGSVTVVGQGDREARMRRRIRRAAV
                     GSSIVSTVLVGVLVWTLLPDGGDDAKDQGVKSPNPVAGSRSPAPTDTAGVPAGSDGSED
                     AADSGEGATEADLLTPDGIRSAVAALKAETGTDRMCRLVVYPEYVSAEVMVDGSKTRYD
                     SWTYRPGEGAQKGIISGSVSPVESPFSAEDFDWDAVPALFERAERELNVKDITTRYLVV
                     EGADPTFGDPMGMSAYLSNKHSQTGYLTADHTGKVTKVMPNEQED"
     misc_feature    complement(3516..3531)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(<3644..3889)
                     /locus_tag="AMK31_RS31975"
                     /old_locus_tag="AMK31_31440"
                     /pseudo=""
     CDS             complement(<3644..3889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192857.1"
                     /locus_tag="AMK31_RS31975"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31440"
                     /product="DoxX family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNIAYWIVAGLLALFYFYAGTLKLIRSRDQLRPMMAWVDRVPLSA
                     LRALGAVEILGATGLILPPLTGIAPSLAPAAAIGFVL"
     gene            complement(4021..4515)
                     /locus_tag="AMK31_RS31980"
                     /old_locus_tag="AMK31_31445"
     CDS             complement(4021..4515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261837.1"
                     /locus_tag="AMK31_RS31980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31445"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_198948608.1"
                     /transl_table=11
                     /translation="MNEEAKTSEPQTDPAVSVVGPGDGETIALGTTHMRVLEDGSHTGH
                     RLAITESVLAPHTQGPPQHRHARHDEGFYVLSGTVRFTVGDEDYDATTGTLVVVPPGTP
                     HTFANPTDQPAVMLSTFTPDLYVQYFRDLQEVLTDGRPLTPQANVDVMRRYATEPATDH
                     D"
     gene            4612..5448
                     /locus_tag="AMK31_RS31985"
                     /old_locus_tag="AMK31_31450"
     CDS             4612..5448
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656053.1"
                     /locus_tag="AMK31_RS31985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31450"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_073944187.1"
                     /transl_table=11
                     /translation="MRYFVAVAEELHFGRAATRLHMSQPPLSRAIKQLEADVGAQLFTR
                     SPTGVTLTAVGSVLLDEARALLGHADRVRVRVSAAAGVTTLTIGILGDGTDPGTARLAA
                     AYRRRHPGIDIHIRDTDLTDPTCGLRAGLVDVALTRAPFDETALTVRPLRTDPVGVVLR
                     ADDPLARRDELRPAELSDRRWFQFPQGTDPIWQSYWNAGRPREGPVVRAVQECLQAVLW
                     NGTVGLAPLGHDLPAELAAVPLNDMPPSQVVAVWNEGDTNPLIRSFIEIATAAYGH"
     gene            complement(5588..5812)
                     /locus_tag="AMK31_RS31990"
                     /old_locus_tag="AMK31_31455"
     CDS             complement(5588..5812)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262305.1"
                     /locus_tag="AMK31_RS31990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31455"
                     /product="hypothetical protein"
                     /protein_id="WP_073944188.1"
                     /transl_table=11
                     /translation="MRMRRILGLVLAAATLAGVSAVGTVSAVGAVSAGAVSSPSISRDD
                     CTAAGGQVIARPYAGYTCALPDGTTQAIT"
     gene            complement(5963..6238)
                     /locus_tag="AMK31_RS31995"
                     /old_locus_tag="AMK31_31460"
     CDS             complement(5963..6238)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669621.1"
                     /locus_tag="AMK31_RS31995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31460"
                     /product="hypothetical protein"
                     /protein_id="WP_073944189.1"
                     /transl_table=11
                     /translation="MRTSIRIAGALTGLTLTLGGVVLAAPAVRADIPACTQMAELAGAT
                     DSAAVTAACSRGVVGDLQGCVTGLTGAGVAGGAATGACRAAAHEPR"
     gene            complement(7122..7349)
                     /locus_tag="AMK31_RS32000"
                     /old_locus_tag="AMK31_31465"
     CDS             complement(7122..7349)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK31_RS32000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK31_31465"
                     /product="hypothetical protein"
                     /protein_id="WP_073944190.1"
                     /transl_table=11
                     /translation="MACVDGGAARLDQADDGQEVRREQRMSVAVDGSVQFWLGLASQSA
                     YSAASTQTAYAQYLDTSDPGGFSLSALTAH"
     misc_feature    7414..7434
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            7970..8137
                     /locus_tag="AMK31_RS40785"
     CDS             7970..8137
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK31_RS40785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158074565.1"
                     /transl_table=11
                     /translation="MAEVKKVARPAVTASSRPCAFVSPDKGNAPTITPARKQAEVVSAP
                     AEQRKECASA"
     misc_feature    8003..8018
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            8279..9862
                     /locus_tag="AMK31_RS32005"
                     /old_locus_tag="AMK31_31470"
     CDS             8279..9862
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602581.1"
                     /locus_tag="AMK31_RS32005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31470"
                     /product="radical SAM protein"
                     /protein_id="WP_073944191.1"
                     /sec_met_domain="TIGR04085 (E-value: 7.7e-09, bitscore:
                     30.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 8.5e-07, bitscore: 23.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNSVYQSSRYVRTLRAAGDRDFTSFGGRLASYEGDDRTMAFHSL
                     FGNARLIDRDIVELLKDASQGISWERLRERVDEDSLRDLVEARFLVEAGHDEAREIDSL
                     LASRQDALSSGVFHSSIQLVLTNACNFSCQGCFAYNFDGGVEERNTSGESVKPGPVLVE
                     LRRSREDAGPVRQDSGPTLAKGDWNHGSDTGRNPSMHMSREVAEKTIQEAIDLRKANGG
                     GHLTVSFFGGEPTLARGTILHVLRTFGDSHDGVTLSYDLTSNGSRIDDELLAALARHRV
                     DTTVSIDYLVPETGEFRGGQQQRTPWAVVRKAILDMKAAGVPVSITTVLSQYTWDKWGT
                     PLIDFVAEAGLDSLDVIVSFQAKEFFDRHSPHEVAQRLLAAVDYGRERGVQLSGYWYQT
                     FQMIIDEAKWAEQADYKTCPAVGRQLSIEPNGSVFACKATARKLGTIDDWRGIFTSPAY
                     QDYGMRAYTNGPGCQGCELQGTCSGGSAGALEEENGSIQVMSPGYCAYMREVVQGLLER
                     HHAHSLAGLS"
     gene            10001..11884
                     /locus_tag="AMK31_RS32010"
                     /old_locus_tag="AMK31_31475"
     CDS             10001..11884
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: Carbam_trans_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602580.1"
                     /locus_tag="AMK31_RS32010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31475"
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_241842789.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 1.2e-15,
                     bitscore: 51.9, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATIGMHFGHDAGAALTDAAGYRVIEAERRLGLRHVCGGNGGFPQ
                     AAAEWLAELRQRAASPVTRIAVADWYTPMCQVLPPALVELVNDDARWTATGGTGLADAV
                     TRVIKPLDWPLAAGFGDITLTAVRHHYAHAALAYYTSGARKALVLALDGTGNYAECGMV
                     CLGDGDQLTPVMSFTNRTGPRFGLVYEALARRVHGSQFDTGKLLGLTATGETDGSLLPV
                     LRAMLVPQSTRRASPDLYERLDEDHLTGTALRYADSWWEYDPDSGGYLDAGLADSSDDD
                     VVHSFGSVFPDEIRTADGRTVQVGTSPDERVCRDLAATLQTAVEHDLIRLVTGISRRFP
                     SYTTLCYAGGCALNITANSRLAECGQFTRVSVPTCCDDSGIALGAALAVADPADRPALT
                     GRSDWASLAYAGPPLEGLDAEDGHPPVPLDDLPRRLAGLGLTARRPADDEDFLQSVADL
                     LADRRCVAWLEGGLETGPRALGHRSLLVSAHWNGARRYVSQTIKHREWFRPVAPICPEE
                     LADQYFTGPLDHTETMLFAVRVRPDRARRLAEARHIDGTARLQTVRPDTQPLLHRLCHA
                     LAARTQLPVLINTSANGGGRPILNHLDEALELLTETELDAVALPEHRLIIQ"
     gene            12018..12935
                     /locus_tag="AMK31_RS32015"
                     /old_locus_tag="AMK31_31480"
     CDS             12018..12935
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: PhyH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602579.1"
                     /locus_tag="AMK31_RS32015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31480"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_073944193.1"
                     /sec_met_domain="PhyH (E-value: 5.9e-13, bitscore: 43.7,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATQLRDIHKTEPLRVLSPADWDHWTSRGYVIVRQAVAPETVTA
                     LTEALYAFLDMRPDDPATWTSPHTGNDRLPGHSGLVEMYNHQAQWDVRQTPRVYEAFAD
                     IWDRPDLWVTIDFANVNPPNRGPRAFDGFIHWDVDTSTDPLPVSCQAVLSLTHGDEEIG
                     GFQCVPEIFTDWEKWVGGQPADRDPFTPDITGYRITTPEVAPGDLIIFNSLLPHGVHPN
                     VSADRVRMAQYLTMAPAWEEHTELRQNRVRFWQDRVPPHPPEGGVRKAEADLYGPARLT
                     DLGERLLGLRTWSEGGVVGQHRPL"
     misc_feature    complement(12032..12050)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            12913..14268
                     /locus_tag="AMK31_RS32020"
                     /old_locus_tag="AMK31_31485"
     CDS             12913..14268
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602578.1"
                     /locus_tag="AMK31_RS32020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31485"
                     /product="MFS transporter"
                     /protein_id="WP_073944194.1"
                     /transl_table=11
                     /translation="MGSTARSRTRPAGRADLGRPFRWLWASAAASNAGDGITRTLLPLL
                     VVAHHPDPAAVAGLTAVNMLPWLLFALPAGVLVDRADRRRIVLGSNLVRAAALLGAALV
                     LADDGPLAALYALAFVLGIAETLADTAAPAMLPRLVDERHLERANGRLSAAQIVLNETI
                     GPPVAGLLMGLTAAVALATGGALYAVAALLLLGLAPLARTPHEPGQGEPTPGEQASRKP
                     TPGEQAPHEPASDERAGGVLGDIRAGLRFVLGHRPLRLTLAASALYGVVFSAAFSMLVL
                     FSARTLGLGETGYGLLLTAGSLGAVAGSWLAPRAADRLPTVRLARWSLAASGAAYVALG
                     LSRHPVPAALALAANGVFMMGWNIPVMSLRQRLTPEDLQGRVMSVSRLCAWGGMPVGAT
                     LGGLLAAAVSVPAVFLVGGAVLSAGALLLLAPLRDDRAPDPGPPKHGDLPDK"
     gene            14349..15284
                     /locus_tag="AMK31_RS32025"
                     /old_locus_tag="AMK31_31490"
     CDS             14349..15284
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602577.1"
                     /locus_tag="AMK31_RS32025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31490"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_073944195.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.7e-28, bitscore:
                     93.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAQLYDTVIVGGGPAGLNGALYLGRSRRRVLLIDSGDARNMAAG
                     VMHNVLTNDGATIADFRARSRAQLTAYDVTFRDDEVVSAESDGDHVVVTTKESGTFRAR
                     TLLYAAGVRSVLPPVPGLADLWGSSVFECPYCHAWEVRERSYAVYGGTVPSECLASTLT
                     VWSDDITYLTDRRELPQDERDRLTAAGVPVRTEGVSELKPHPEGVEVVFEDGRSTAYGA
                     LFLHLDIEPRVDPLRPWLQAPDLESVQTDDRGRTSLPRLYVAGDLGRNMQQAAMAAASG
                     GLAAMAINADLIREDRPGSLPEPPPPTPAR"
     gene            15338..16255
                     /locus_tag="AMK31_RS32030"
                     /old_locus_tag="AMK31_31495"
     CDS             15338..16255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555037.1"
                     /locus_tag="AMK31_RS32030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31495"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_073944196.1"
                     /transl_table=11
                     /translation="MTSPRAEFTPHMEHYTFVLEDQPYLGYFQYGNEKTPVYTTDRHGF
                     RVTPGPGELRATVGDDRPDGPARVLAGSSAVFGVGATSDAATITARLWNTHAPRLPWLN
                     MAGQSHNSAQELLLFTLFRHELPPVEDIVLLSGVNNLVLSRLPEDKQGRHGAFFDCGPA
                     PDVVPPPDQRVTHATELTIRHLSGWKLLADALGARLTFVLQPLAPWVREEPLPREKLLF
                     DELDEVSNFRRFHNDISTMAVGRAYARRLADGCARLDVPFLDMNVALGEAAGPEDWLFI
                     DRVHCTDLGYDLVARQLADRLDLA"
     gene            16267..16464
                     /locus_tag="AMK31_RS32035"
                     /old_locus_tag="AMK31_31500"
     CDS             16267..16464
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK31_RS32035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK31_31500"
                     /product="hypothetical protein"
                     /protein_id="WP_073944197.1"
                     /transl_table=11
                     /translation="MRDDSSAAPASAARRLASWLRDRGRPVPPADAQPDDQSTTAEPPA
                     PPPTRLRPQPEDDASVYPLF"
     gene            16481..18361
                     /locus_tag="AMK31_RS32040"
                     /old_locus_tag="AMK31_31505"
     CDS             16481..18361
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: Carbam_trans_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602574.1"
                     /locus_tag="AMK31_RS32040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31505"
                     /product="carbamoyltransferase"
                     /protein_id="WP_073944198.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 3.5e-86,
                     bitscore: 283.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTARADRRGTGGAERPVLGISAYYHDSAAALVADGVPLAAAQEE
                     RFTRRRHDSGFPAHAVASCLREAGLRLDELAAVAFYEDPALKFRRVLATWLATAPHGFP
                     VFRRAFPQWAGWKRRALDDVRAHLRELAPGQTLPPVVAYRHHASHAASAFFPSPYPSAA
                     VLCVDGVGEWATTTLWHGRGTDLVPLAELRFPHSLGMLYSAFTYFCGFKVDSGEYKLMG
                     LAPYGTPRYAPLIRERLIDIKPDGSFRLDLRHFTFQYGRTMVGRAFEELFDGPRRTPEG
                     PLTEREFDLAASVQQVTEEVLLRLARTALERTGERRLCLAGGVALNCVANGRLLADGVC
                     DELWIQPAAGDAGGSLGAALAESHRRGAPRAHVARGSDAMAGSLLGPAHSDREIAEFLT
                     DHGYPAVRLPERKLTERVAAELARGRVVGWFQGRMEFGPRALGNRSILADPRDPATQST
                     LNLKTKFRESFRPFAPAVLAEDAKDWFDLAQESPYMLLTAQVAAARRREIEPPAEGVKG
                     LDLLRVPRSTIPAVTHVDGSSRVQTVTAEHNPRFHALLTAFRDRTGCPVLVNTSFNVRG
                     EPIVRTPQEAYACFMRTRIDLLVLGDHLLDKRDQPEWREEADWRATIPMD"
     gene            complement(18508..19134)
                     /locus_tag="AMK31_RS32045"
                     /old_locus_tag="AMK31_31510"
     CDS             complement(18508..19134)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555040.1"
                     /locus_tag="AMK31_RS32045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31510"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_073944199.1"
                     /transl_table=11
                     /translation="MTRSATLAGVFDDLADGYDHGHHEEIARALIAWVGPGAVGAVADV
                     ACGAGAVAVQLARGRERAARPVLAVDLSSRMIAVGRARAAGLVPDTAIDWRVGDAVPLP
                     VADGSLDLVLCASSLHFLGRRASADWRRAVRPGGRVGFSLPLATHFRPSERFSRLLAED
                     VPLPRTAEEASALVTECGFTGAESRVHVLGTRRVVLTSATRPDHP"
     gene            19978..20433
                     /locus_tag="AMK31_RS32050"
                     /old_locus_tag="AMK31_31515"
     CDS             19978..20433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642399.1"
                     /locus_tag="AMK31_RS32050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31515"
                     /product="VOC family protein"
                     /protein_id="WP_073944200.1"
                     /transl_table=11
                     /translation="MEMTVQLTIDCSDPQRMVTFWAEALGYVPEPPPGGHATWRAYWAA
                     AGVPEAELPAGAGDVPESIIDPAGRGPRVWFQQVPEPKVAKNRWHFDLKVGGGRDVPLD
                     IRTQRVKATVERLVKAGATVLRIKDEPDMGLYAAAMQDPEGNEFDIV"
     gene            complement(<20899..>21156)
                     /locus_tag="AMK31_RS32060"
                     /old_locus_tag="AMK31_31525"
                     /pseudo=""
     CDS             complement(<20899..21156)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_053126455.1"
                     /locus_tag="AMK31_RS32060"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AMK31_31525"
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIEELLEGPPLSSVLTSMPGAGVRTGARVLIEIGDRSTFRTASHF
                     AAYAGLAPATSSSGPSNRGEQPSKRGNKQLERAFLHAAFAA"
     gene            21340..21636
                     /locus_tag="AMK31_RS39325"
                     /old_locus_tag="AMK31_31530"
     CDS             21340..21636
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024584.4"
                     /locus_tag="AMK31_RS39325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31530"
                     /product="SPASM domain-containing protein"
                     /protein_id="WP_079187021.1"
                     /sec_met_domain="SPASM (E-value: 1e-08, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGLCGYCWSGKLAVAPDGKVFTCVMARDWPVGDVLSQSLGEILQ
                     GAELAQVRREIHETVWLPATAGDERCPQSCGPDLSCPCDPLLCEKCCGPTHLQ"
     gene            complement(21986..23077)
                     /locus_tag="AMK31_RS32075"
                     /old_locus_tag="AMK31_31540"
     CDS             complement(21986..23077)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474010.1"
                     /locus_tag="AMK31_RS32075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31540"
                     /product="hypothetical protein"
                     /protein_id="WP_073944201.1"
                     /transl_table=11
                     /translation="MPNDALHGGPTQVAAGLVATAAAPLDPASADAPQVLHWPKRRLLV
                     QRGDTELAVRDLDGEGTEIRFPAPWPRRYGSVAVSPTGDVAVFAGVHALRAVDSTGAVR
                     WEIRHGCWSPAVCTGAHASFSEYADDYHHGHADLGSAAFSADGKLLWAHVRNRAGRDVN
                     EEWLILDPADGTVLTRADTMTVGSGSLHFPHPNPAYMGLTVGEGEENSPVLWGHWDGTN
                     LTVQRFVEEVLLAVSPSGEHFLTTDLGQWTLYLHRAEDGIELRHLDADEAVPLPASSDD
                     DRVRWDYEAAAFPYDDTAVVGTEDFVEDPRHWFVDPHTMVVRGRIAYPFPVSGPPRSAG
                     QGAWYTVSKDQTTLHLWNLPHPE"
     gene            complement(<23256..24034)
                     /locus_tag="AMK31_RS32080"
                     /old_locus_tag="AMK31_31545"
                     /pseudo=""
     CDS             complement(<23256..24034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183161.1"
                     /locus_tag="AMK31_RS32080"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AMK31_31545"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLSYPATIPLPSRTLNHLAERIRNHRHQRRSRWRRLDPGRQALLT
                     LAHLRNGDTYTRLAAGFGIGAPPPGATSVKPSTCSPQPRTTWTPSWTVSASWRTRSSTA
                     H"
     misc_feature    complement(24235..24249)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(24334..24732)
                     /locus_tag="AMK31_RS32085"
                     /old_locus_tag="AMK31_31550"
     CDS             complement(24334..24732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572078.1"
                     /locus_tag="AMK31_RS32085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_31550"
                     /product="DUF6234 family protein"
                     /protein_id="WP_073944202.1"
                     /transl_table=11
                     /translation="MTDALPAQVRRRPWAHRTRLGVDLALAIPLFLLETAWLVLDWTYG
                     YGLEVWAAQGEQARIDAAGLAHIGRVRMLLIAVLVLAVLAALFRARWTVITHLLVALLA
                     GGSLTAAQQEWDDSHTSPPGCIRYSANC"
     misc_feature    25923..25938
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            26296..26766
                     /locus_tag="AMK31_RS32095"
                     /old_locus_tag="AMK31_31560"
     CDS             26296..26766
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK31_RS32095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK31_31560"
                     /product="hypothetical protein"
                     /protein_id="WP_143204281.1"
                     /transl_table=11
                     /translation="MEMSFRKLPDNQHEILVRARKGPDVRLPAQPVGPNMPHDLVHAVV
                     ETALGINDGFWGAMARGATFQGFELLTPGRHRRSGMKVLRRGGDAVMAAELSVNWAYRV
                     WRGLSTEGRGVGPAPLDSDALARTLPRLNAAATRWTAVPQGGELLWRWGSDH"
     gene            27343..27891
                     /locus_tag="AMK31_RS42330"
     CDS             27343..27891
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070744.1"
                     /locus_tag="AMK31_RS42330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_338013059.1"
                     /sec_met_domain="PCMT (E-value: 5.9e-07, bitscore: 23.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPDAPGTADAEQVNAAMWHTYGAHHLDRATPLPEVDEIAWGPA
                     GTGPGDAVLGDLRGLHVLDLGCGPGRHAAHVARTHHATVDAVDFSRTQIARARARYGDL
                     PGLRLIQADAVGHLHASAPYDVIYSLSAVHFIDPHRLLPALAAALRPGGRRAHVGTHDK
                     AVDGPARAARAAHRGGHRA"
ORIGIN
        1 tcgcgctgtt cgacgtcccg ttcacggtgg cggcgatgac cggtgtgatc ctcgtggtct
       61 ccgggccgac cgtcgtcggc ccgatcctgg agcacgtcag acccacggat cgcctgcgaa
      121 ggatcctgac ctgggaaggt tccttgatcg accccgtcgg gggcattctc ggtgcggtcg
      181 tcttccacat catcgtccgg tcccaggaaa accgtgagtt ccgtttcggg atcttcgtcg
      241 gcggcatggc cgtcgggctg atcggcggtg tggtcggcat cacgctgctg tggctggcac
      301 tgcggcgact gcggctgggc ggaacgctcg ggacactcgc gcagttggcg agcgtcgtcg
      361 cggtctccgc cggatgcgac atggtcttcg acgacacggg cctcatcgcg gccatcgtca
      421 tgggtatcgc ggtggcgaac ctgcccggat tcgacatgcc ggcacgacga ccgttcttcg
      481 agaccgtcgt cgaactgacc atcggtctgc tgttcatctc gatctcggcc acggtcgagc
      541 cgaagtccgt cgcaccggtg atcctgccct cgctcgccct catcgccgtg ctcgtcgtgg
      601 tggtcagacc gctggtggcc ctctgcgcgg cagcccggac ggacctcggc tccggggaac
      661 gcggcttcgt cgggtggatg gcgccccgcg gcatcgtcgc cgcctgcacc gcctccacgt
      721 tctcgacctc gctcgtcgac aagggagtgc acgacgccga caagatcctc ccgatcacct
      781 tcctcgtcat cgtggggacg gtcctggtct acgcgttgac ggcagggccc gtggccgcca
      841 ggctcggcgt cgcccggtcg acgcgcaccc ggccgctgct cgtcggcgga agctcctggg
      901 cgatcgatct cgcgcgggcg ttgcgcgcgg cgggactgga cgtgctgatg tgggccggtc
      961 ccgcgacgga acgggagcgg atcatggaat cggacatcga actggccgcg ggagaactct
     1021 tcgccgcgat caccaacccc caagccatgc tggagggggt cacggcagtt ctcctgctca
     1081 ccgacgacga cgacttcaac gcgctcgcct cggtggtcat gcaggacagg gtcgaaggcc
     1141 cggtctatcg cgtcgcccca ccgccgggca gccagggtgt cgtcgccccg tacaccggcg
     1201 ggcacgtcct gttcgggccc gatctcggcg ggcgcacgct gacgtcccgt cacgaacgag
     1261 gcgcccgctt ccgtgtgcag tcggctgccg aggcggttcc gcccggacac gagaccctgt
     1321 tcgtcgtccg cgccgagggc ctgctcgagc cagtcacgga agggcaggca gcctcgttca
     1381 cgagggcgga caccctcgtc cttctagggc cggccgacac cgatgcgcta cccgaccgga
     1441 gcacgtgaag accgtactga ctcgcgactc gacacccggc ccggccggtc cgtcgcgctg
     1501 acggtgtgaa cccgcatcgc ggcctcgccg tcacctctcc gaggccgcgg cccgtcggct
     1561 cgcgcgacgc ccggggcgac ctttcgacgc cggtcatgct aggcaacgcc ccgtgtccgg
     1621 aggcgccagg tgccgccccc ggtgatgccg tgagatggca aacctcgacc cgcctcgccc
     1681 ctggccgcga cggccctcag tcctcctgct cgttgggcat caccttggtc accttgcccg
     1741 tgtggtccgc cgtgagatag ccagtctggc tgtgcttgtt ggagaggtag gccgacatgc
     1801 ccatcgggtc gccgaaggtc gggtcggctc cctccaccac caggtaccgc gtggtgatgt
     1861 ccttcacgtt cagttcccgc tcggcccgct cgaacagggc ggggacggcg tcccagtcga
     1921 agtcttcggc gctgaacggg ctctccacgg ggctcaccga cccgctgatg atgcccttct
     1981 gcgcaccttc ccccggccga taggtccagg agtcgtaacg ggtcttgctg ccgtcgacca
     2041 tgacctcggc ggagacgtac tccgggtaga cgacgaggcg gcacatacgg tccgtgcccg
     2101 tttcggcctt gagtgccgcc acggcgctgc ggatgccgtc cggggtcagc aggtcggcct
     2161 ccgtcgcgcc ctcaccggag tccgccgcgt cttcggagcc gtcgctgccc gctgggacac
     2221 cggcggtgtc ggtcggagcg ggggagcggg agccggcgac ggggttcggc gacttcacgc
     2281 cctggtcctt cgcgtcgtcg ccgccgtcag gaaggagcgt ccacaccaac accccgacga
     2341 gcaccgtgga gacgatcgag gaaccgacgg cggcacggcg gatccgccgc cgcatccgcg
     2401 cctcgcggtc tccctggccg acgaccgtta ccgaacctgg cagcgggtgg tgctgcggct
     2461 gcccgagcgg cggggtgtcg cggacggagt gcgcgctcgg gaagggcggg ttcggcgtgt
     2521 gctgcgcgtg cggcgcgtat ggagaggact gcgacgacga ctccggggga gctgtcggtg
     2581 tcggggcggt gtggggaagc gaaccggagg acggtgccgc gccagccgta accgggccgg
     2641 cgggtctccg cgccgacgcg tccggcgggg ccagacggaa tgaggtcgtg ccggtgcgat
     2701 cggctgccga gtccggcgtc ggtccctctg ccgcctcggc gagcatggcg tccacggtgg
     2761 ctgcgtccgg tcgccgagcc gggtccttcg tcaacgccgc gtcgaggagg ggcccgagaa
     2821 ctcctgcctg ccggggcggc ggcagttcct cgttcaggac ggccgccagc gtggccagcg
     2881 tacttcctct gcgaagcggg tggtggcctt cgacggccac gtacagcatc atcgcgagcg
     2941 accacaggtc ggattccggg ccgccctcgc caccggagac gcgctccggg gccatgtagt
     3001 caggcgtgcc gatgatggaa ccggtggcgg tcagaacggt cgactcgcgg atcgcggcga
     3061 tgccgaagtc ggtgagcacg ggacgcccgt cggtacgcag cagcacgttc gcgggcttga
     3121 cgtcccggtg ctggattccg accgcatgcg cggcgcgcag cgcgccaagc acctcgcggc
     3181 tcagccgggc cacctcccgc ggctccatcg ggccgcgggc gaggcggtcg gcgagggaac
     3241 ctccggtgac cagctccatg acgagccatg ggtacgggta cccggcgccg tccaccacat
     3301 gatggatggt gacgacgttc gggtgctcga cgcgggccag cgcccgggcc tcgcgcagca
     3361 cccgggcacg cagaagcgcc gcggcctccg ggtcgtactc ggcgagcccc gggtcgggcg
     3421 gacgcacctc cttcaacgcg acggcgcgat ccagtacgac gtcgcgcgcc cgccacaccg
     3481 tgcccatgcc gccaccgccg agccgcgcct ccagctcgaa ccggccgtcg atcacccgtc
     3541 tgccgggctc cccctcgttc atggcgtgga gcatacgaga acggagtgac ggcgaacgca
     3601 gcacctcgct catcgcacgt catcgcacgt cgccggtctg cgggagtacg aagccgatgg
     3661 ccgcggccgg tgccagcgag ggggcgatgc cggtcagcgg cggcaggatc aggccggtcg
     3721 cgccgagtat ttcgaccgct cccagcgccc tgagggcgga caagggcacg cggtcgaccc
     3781 aggccatcat cggtcggagc tgatcgcggc tgcggatcag cttcagcgtg cctgcgtaga
     3841 agtagaagag cgcgagcagt cccgcaacga tccaataggc gatgttcatc gttgcccgtt
     3901 catggttccc gtgcacgggc caccggttca cgggccaccg gttcaccggg acgggtcgat
     3961 tgcgtcgctt gccagaagag ccctggtgaa ggcccggtcc gtgtcgcgcg cgccttcggt
     4021 tcagtcgtgg tcggtggcgg gctcggtcgc gtagcggcgc atcacgtcga cgttggcttg
     4081 cggcgtcaac ggccggccgt cggtgagcac ctcctggagg tctcggaagt actgcacgta
     4141 caggtcgggg gtgaatgtgc tgagcatgac ggcgggttgg tcggtcgggt tggcgaaggt
     4201 gtgcggggta ccgggcggaa ccaccacgag cgtgcccgtg gtggcgtcgt agtcctcgtc
     4261 cccgacggtg aaccgcacgg tgcctgagag gacgtagaag ccctcgtcat gccgggcatg
     4321 acggtgctgc ggcggcccct gggtgtgcgg ggcgaggacg gactcggtga tcgcgagacg
     4381 gtgcccggtg tggctgccgt cctccagaac gcgcatgtgc gtggtgccca gagcgatcgt
     4441 ctcgccgtcg ccgggaccca ccaccgatac agctgggtcg gtctgcggct cgcttgtctt
     4501 cgcttcttcg ttcatgccca cgagtgcacc gccggggacc tcccggtgtc caagacccat
     4561 cccgcggcgc cgatacctcg tgggtaatgt tgcagcgtgg agctacggac cttgcggtac
     4621 ttcgtggccg tcgccgagga actccatttc ggccgggccg ccacccgact gcacatgagc
     4681 cagccgccgc tgagccgggc gatcaagcag ttggaggccg atgtcggggc ccagctgttc
     4741 acccgctcgc ctacgggggt cacgctcacc gcggtgggct ctgtgctgct cgacgaggcg
     4801 cgagccctgc tcggccacgc cgaccgcgtc cgggtacgcg tgagcgcggc cgccggcgtc
     4861 acgaccctca ccatcggcat cctgggcgac ggcaccgacc cgggaacggc caggctggcc
     4921 gccgcctacc gccgacgcca ccccggcatc gacatccaca tccgcgacac cgatctgacc
     4981 gacccgacct gcgggttgcg cgccggactg gtcgacgtcg cgctgacgcg agcgccgttc
     5041 gacgagactg ccctgacggt gcgtccactg cggaccgacc cggtcggcgt ggtcctgcgc
     5101 gcagacgatc cgctggcccg ccgcgacgaa ctgcggccgg ccgaactgag cgaccgccgc
     5161 tggttccagt ttccccaggg caccgacccc atctggcagt cgtactggaa cgccggcagg
     5221 ccgcgcgagg gcccagtggt gcgcgccgtc caggaatgcc tgcaggccgt actgtggaac
     5281 ggcacggtcg gcctggcccc gctcggacac gacctgcccg cggagctggc cgcggtgccg
     5341 ctgaacgaca tgccgccgag ccaggtggtg gcggtgtgga acgagggtga caccaacccg
     5401 ttgatccggt ccttcatcga gatcgcgaca gctgcgtacg gtcactgagc accggcggcc
     5461 ggcgctgcac tgccgcgatc ctcggccgcc gggccgcttc cccaccccct tcccgggcag
     5521 cccggcaccc agacccacgg cgccgggtgc accggccggg cttgttgccc agccgtgcgc
     5581 cgaccggtca agtgatcgcc tgcgtggtcc cgtcaggcag cgcgcaggtg tagccggcgt
     5641 aggggcgtgc aatgacctgt ccgccggcag ccgtgcagtc gtctctggag atgctcggag
     5701 acgagacggc cccggcgctg acggcgccga cagcgctcac agtgccgacg gcgctcacac
     5761 cggcaagggt tgccgcggcc aggacgaggc ccaggattct tcgcatgcgc atggcttcct
     5821 cctcctctca ggcgccttcg ttcggccttc gggaaggaca agcctcaaga cgacggcgcc
     5881 ctcatactca gcatgggcgc tccgaatgag gcccgcgagg cgaggctggg cgccaccgtg
     5941 agcggctgcc gcacgcgctc ctctaacgcg gttcgtgggc cgccgcccgg caggccccgg
     6001 tcgcggcgcc gcccgccact ccggccccgg tcagtccggt cacacaaccc tgcaggtctc
     6061 cgaccacgcc acggctgcag gccgctgtga cggcggcgga atcggtggca ccggccagct
     6121 cggccatctg tgtgcaggcg gggatgtccg cccggaccgc gggagcggcg aggaccacac
     6181 cgcccagggt gagggtcagg ccggtgaggg caccggcgat acggatcgac gtgcgcatgg
     6241 gacgcacctg ccttccgggt tggtcgcgcg gtcctggtca gggtgggccg gatccacgcg
     6301 gcaaggccca ctcggacctc cactcacggg cccctcactc cagcgttgca tcctctccct
     6361 cgcccgtcct gggcacccga gggacggccg cgctgagtaa ctgcgattac gcgaagcgcg
     6421 gtagccggcc cgtccggccg accaggtgga cggccggccc agcgtccccc cgacctgtcc
     6481 cctgcacacc ggcggagacg gtccaccacg ggacccggcg ggatcgacgt cgagaccacc
     6541 gctgagcttc cgccggtagg cctcgcgctg gctccggggc tgttcgaggg aaacagtgga
     6601 cagtgccgcg tgccgagtga tctcccaacg cctacgccgc aaccctgtcc ctaggcacat
     6661 cagctattgg taccagggaa gaaaggcggt cgagtgaagc tcaccaagcg gttggccacg
     6721 atcagcaccg ctgcgacggc agcggccctc ctcagcgccg gtggcgccca ggctcaagac
     6781 gacgggggac tcctctcact tgtgggtaac tcgcctctcc tccaggtctg ttacccaatg
     6841 ggacaggtcg gacaagggaa ctccttcacc ggcactcaga acatcaactg cagccagaac
     6901 actgaggtga cgtcacccac gaacggcaat ggaggcggtg tgacgggggc cgaagtcgcc
     6961 atcggggaaa cccgcgttgc ccctggcacc tccggaactg ccatcgcgac ctgcccagaa
     7021 ggcaaagtcg ccactggggg aggcttcggc agagcgggag gcccccctgt ccgctacacc
     7081 tcctcgttcc ccctcgtgga ggacttcgac acacccccaa ctcaatgggc ggtcaacgct
     7141 gacaacgaga acccgcccgg gtccgaggtg tccaggtact gggcgtacgc ggtttgcgtc
     7201 gacgccgccg agtaagcgga ttgtgacgcc agcccgagcc agaactggac gctgccgtcg
     7261 acggcgaccg acatgcgctg ctcgcgccgt acctcctggc cgtcgtccgc ctggtcgagc
     7321 cgggcagcgc caccgtcgac acacgccatc gccgagtcgc tgtacgccga gttccgcgaa
     7381 ccccgtaggc gccgcccctg ctgctgtccc gggtgctggt caccgaggcg atgacccaat
     7441 ccttcgccaa cacccccgtc gacgtgcaac gcgacgcggg gacgccgcac cgccggcggt
     7501 cgtcctggcc cgcgtcctgc gcaacctggt gcagtccgac cccgaactgc accaggaacc
     7561 ggcgcctgtg gcaagaactg cccagtcgca cacctgggca gccgacgcag tacgacgcgg
     7621 tcaccctgga caccccactc acctccatct gacggcacgt cgcccgcccc cggcccgtcg
     7681 tagaccgcac cgacggagta gaccctcccc ccacccttgg ccggaatcag taccgccccc
     7741 gcgcattcag atggatttcc acgccgcccc cgccggtccg gatcaagcag atatcgcagg
     7801 cgaatcggca gacgagaaag ctgcacaccg actaccgata gatcaattcc tccctgagga
     7861 tgaacgacaa acacgccttc tcaacggtgt ccgatagcag cgctattcga ctcggtttcc
     7921 ttctgcttca gtgagacgcg ttgtgtgacg cacctatgga ggaggccaca tggccgaagt
     7981 caagaaggtc gcccgtcccg cggtcaccgc gtcgtcccgt ccctgcgctt tcgtctcgcc
     8041 ggacaagggc aacgctccga ccatcacgcc cgcccgcaag caggctgagg tcgtctcggc
     8101 ccccgctgag cagcggaaag agtgtgcgtc ggcctaaggg ctgaggctcc ccggggcccg
     8161 cccgcaggcc gggcaggccc cggtctgtgc gctgccgcgc gccgcgctcc gtcgagggcc
     8221 caccagcgcg ccgtacgtcc gcatcggaag tcgtgagacg cagggagaaa actcagccat
     8281 gcagaattcc gtctaccagt cctcgcgcta cgtccgtacc ctgcgcgccg cgggcgaccg
     8341 cgatttcacg tcattcggag gccggctcgc ttcctacgag ggcgacgacc gaaccatggc
     8401 ctttcattca ctcttcggaa atgcccggct gatcgaccgg gacatcgtcg aactcctcaa
     8461 ggacgcctcc cagggcatca gctgggagcg cctgcgcgag cgggtcgacg aggactcgct
     8521 gcgcgacctc gtcgaggccc gtttcctggt cgaggcaggt cacgacgagg cccgggagat
     8581 cgacagcctg ctggcgagcc ggcaggacgc gctcagcagc ggtgtgttcc actcctccat
     8641 ccagctcgtg ctcaccaacg cctgcaactt ctcctgtcag ggctgcttcg cgtacaactt
     8701 cgacggcggc gtcgaggagc gcaacacctc cggcgagtcg gtgaaacccg gcccggtcct
     8761 ggtcgaactg cgccgctccc gcgaggacgc cggccccgtc cgccaggact cgggccccac
     8821 cctcgccaag ggcgactgga accacggctc ggacaccggc cgcaacccct cgatgcacat
     8881 gtcgcgcgag gtcgccgaga agaccatcca ggaggccatc gacctgcgca aggccaacgg
     8941 cggcggccat ctgacggtgt cgttcttcgg cggcgagccc accctggcac gcggcaccat
     9001 cctgcacgtg ctgcgcacct tcggcgacag ccacgacggc gtcaccctct cctacgacct
     9061 caccagcaac ggctcccgca tcgacgacga actgctggcg gcgctcgcca ggcaccgcgt
     9121 cgacaccacc gtgtccatcg actacctggt ccccgagacc ggcgagttcc gcggcggcca
     9181 gcagcagcgc accccgtggg ccgtggtccg caaggcgatc ctcgacatga aggccgcggg
     9241 cgtcccggtc agcatcacca ccgtgctgtc ccagtacacc tgggacaagt ggggcacccc
     9301 gctcatcgac ttcgtcgccg aggccggcct ggacagcctc gacgtcatcg tgtcgttcca
     9361 ggccaaggag ttcttcgacc ggcacagccc gcacgaggtg gcgcagcggc tgctggccgc
     9421 cgtcgactac gggcgcgaac gcggcgtaca gctcagcggc tactggtacc agaccttcca
     9481 gatgatcatc gacgaggcca agtgggccga gcaggccgac tacaagacct gcccggcggt
     9541 cggccgccag ctgtccatcg aacccaacgg cagcgtcttc gcctgcaagg ccaccgcccg
     9601 caaactgggc accatcgacg actggcgcgg catcttcacc tcacccgcct accaggacta
     9661 cggcatgcgg gcctacacca acggccccgg ctgccagggc tgcgaactcc agggcacctg
     9721 ctcgggcggc tccgccggag cgctggagga ggagaacggc tcgatccagg tcatgtcgcc
     9781 cggctactgc gcctacatgc gcgaggtcgt ccagggcctg ctggagcgcc accacgccca
     9841 cagcctcgcc ggcctctcct gacccgggtt ccccgacgtt ccgcaccggc ccgccccgcg
     9901 cggggcatcc gcaccggccc gccccccgcg cgaggcgggc catcgagcca cgacccggaa
     9961 ccgccgcgcc ggtccgggcc caggaagggt gactggttcc ttggcaacca tcggtatgca
    10021 cttcggtcat gacgcgggcg cagcgctcac cgacgcggcc ggctaccgcg tcatcgaggc
    10081 cgaacgccgc ctcggactgc gccatgtctg cggcggcaac ggcggcttcc cgcaggccgc
    10141 cgccgagtgg ctggcggagc tgcggcagcg ggcggcgagc ccggtcaccc ggattgccgt
    10201 ggccgactgg tacacaccga tgtgccaggt gctgcccccc gcactggtcg aactcgtcaa
    10261 cgacgacgcc cgctggacgg ccaccggcgg cacgggcctc gccgacgcgg tcacccgcgt
    10321 catcaaaccc ctcgactggc ccctggccgc gggattcggc gacatcaccc tgaccgccgt
    10381 acgccaccac tacgcgcacg ccgccctcgc ctactacacc tccggtgccc gcaaggccct
    10441 ggtgctggcc ctggacggga ccggcaacta cgccgagtgc ggcatggtgt gcctcggcga
    10501 cggcgaccag ctcaccccgg tgatgtcctt caccaaccgc accggaccgc gcttcggcct
    10561 ggtctacgag gcactcgccc ggcgcgtcca cggcagccag ttcgacacgg gcaagctgct
    10621 cgggctgacg gccaccgggg agaccgacgg ctcgctgctg ccggtgctgc gcgccatgct
    10681 cgtcccgcag tccacccggc gcgcctcacc cgacctgtat gaacggctcg acgaggacca
    10741 cctgaccggc accgcgctgc gctacgccga ctcctggtgg gagtacgacc cggacagcgg
    10801 cggatatctg gacgcgggcc tcgccgactc atcggacgac gacgtcgtgc actccttcgg
    10861 ctccgtcttc cccgacgaga tccgcaccgc ggacggccgc accgtccagg tcgggacctc
    10921 ccccgacgag cgggtgtgca gggacctcgc ggccaccctg cagaccgccg tggagcacga
    10981 cctgatccgg ctggtcaccg gcatcagccg acggttcccc agctacacca ccctctgcta
    11041 cgcgggcggc tgcgccctca acatcaccgc caacagccgt ctcgccgagt gcggccagtt
    11101 cacccgggtg tccgtcccca cctgctgcga cgactcgggg atcgcgctgg gcgccgccct
    11161 ggccgtcgcc gaccccgccg accgccccgc cctgacgggc cgctcggact gggcgtccct
    11221 cgcctacgcc ggaccgccac tggagggcct ggacgcggag gacggccacc ccccggtgcc
    11281 gctcgacgac ctgccccggc gcctcgccgg cctcggactg accgcgcgcc gcccggccga
    11341 cgacgaggac ttcctccaga gcgtcgccga cctgctggcc gaccggcggt gcgtggcctg
    11401 gctggagggc ggactggaga ccggaccacg ggccctgggc caccgctccc tgctcgtctc
    11461 cgcccactgg aacggcgccc gccggtacgt ttcccagacg atcaaacacc gcgagtggtt
    11521 ccggccggtc gcgccgatct gccccgagga actggccgac cagtacttca ccgggcccct
    11581 cgaccacacc gagaccatgc tgttcgcggt gcgcgtgcgg cccgaccggg cccggcggct
    11641 cgccgaggca cggcacatcg acggcacggc ccgcctgcag accgtacggc ccgacaccca
    11701 gcccctgctg caccggctgt gccacgcgct cgccgcccgc acacagctgc ccgtactcat
    11761 caacaccagc gccaacgggg gcggccgccc catcctcaac cacctggacg aggcactgga
    11821 gttgctcacc gagaccgaac tggacgccgt ggcgctgccc gaacaccgcc tcatcatcca
    11881 gtgattccag atccagtgct ccgagatcca gtgatccgca accagcggtc cgcatccagt
    11941 ggtccgcacc gagtgatcac gccatacgcc gccgtccacc acccgaaccc gctccccgcc
    12001 cgcacaggag agtgcccgtg gccgccaccc aactgcgaga catccacaag acggaaccgc
    12061 tgcgcgtcct gtcccccgcg gactgggacc actggaccag ccgaggctat gtgatcgtcc
    12121 gtcaggccgt ggcgcccgag accgtcaccg ccctcaccga ggccctgtac gccttcctcg
    12181 acatgcgccc cgacgacccc gccacctgga cctccccgca caccggcaac gaccgcctgc
    12241 cgggccacag cgggctggtc gagatgtaca accaccaggc acagtgggac gtccgccaga
    12301 ccccgcgggt gtacgaggcc ttcgccgaca tctgggaccg ccccgacctg tgggtcacca
    12361 tcgacttcgc caacgtcaac ccgcccaacc ggggacctcg agccttcgac gggttcatcc
    12421 actgggacgt ggacacctcc accgacccgc tccccgtcag ctgccaggcc gtgctctcgc
    12481 tgacccacgg cgacgaggag atcggcggct tccagtgcgt cccggagatc ttcaccgact
    12541 gggagaagtg ggtcggcggc cagcccgccg accgcgaccc cttcaccccc gacatcaccg
    12601 gctaccggat caccaccccg gaggtcgcac ccggtgacct gatcatcttc aacagtctgc
    12661 tgccgcacgg cgtgcacccc aacgtctccg ccgaccgggt gcgcatggcg cagtacctga
    12721 ccatggcgcc cgcctgggag gagcacacgg aactgcggca gaaccgggtg cggttctggc
    12781 aggaccgcgt cccgccccat cctcccgagg gcggggtgcg caaggccgag gccgacctgt
    12841 acgggccggc gagactgacc gacctgggcg aacggctgct gggcctgcgc acgtggagcg
    12901 aggggggcgt tgttgggcag caccgcccgc tctagaaccc ggccggccgg ccgggccgac
    12961 ctgggccgcc cgttccgctg gctgtgggcg tcggcggccg cctccaacgc cggtgacggc
    13021 atcacccgta cgctgctgcc gctgctggtg gtcgcgcacc accccgaccc ggcggcggtc
    13081 gccgggctga ccgccgtcaa catgctgccc tggctgctgt tcgcgctccc cgcgggcgtg
    13141 ctcgtggacc gcgcggaccg gcggcggatc gtgctgggca gcaacctggt ccgcgcggcc
    13201 gccctgctgg gcgcggccct ggtgctcgcc gacgacggcc cgctggccgc cctgtacgcg
    13261 ctggcgttcg tgctcggcat cgccgagacc cttgccgaca ccgccgcccc cgcgatgctg
    13321 ccgcgcctgg tcgacgagcg gcacctggag cgcgccaacg gccggctgtc ggcggcgcag
    13381 atcgtgctca acgagacgat cggaccgccg gtcgccggcc tgctcatggg cctgaccgcc
    13441 gccgtggcgc tggccaccgg cggggcgctg tacgcggtgg cagcgctgct gctgctcggc
    13501 ctagccccgc tcgcccgcac accccacgag ccgggacagg gcgagccgac accgggcgag
    13561 caggcatccc gcaagccgac accgggcgag caggcacccc acgagccggc atcggacgaa
    13621 cgggcaggcg gagtgctcgg cgacatccgg gcgggactcc gcttcgtcct cggccatcgc
    13681 cccctgcggc tcaccctggc cgccagcgcc ctgtacggcg tcgtgttctc tgccgccttc
    13741 tccatgctgg tgctgttcag cgcccgcacc ctggggctgg gcgagaccgg ttacggactg
    13801 ctgctgaccg ccggttcgct gggcgcggtc gccggcagct ggctggcccc ccgggccgcc
    13861 gaccggctgc ccaccgtccg gctggcccgc tggtccctgg ccgcgtccgg ggccgcgtac
    13921 gtcgcgctgg gcctgagccg ccacccggtc ccggccgcgc tggcgctcgc cgcgaacggc
    13981 gtcttcatga tgggctggaa catccccgtg atgtcgctgc gccagcggct cacacccgag
    14041 gacctgcagg gccgggtgat gagcgtgtcc cggctgtgcg cgtggggcgg catgccggtc
    14101 ggcgccacac tcggcggact cctcgccgcg gccgtctccg tcccggcggt gttcctcgtg
    14161 ggcggggccg tcctgtccgc gggcgcgctg ctgctgctcg cgcccctgcg cgacgaccgc
    14221 gctcccgacc ccggcccgcc gaagcacggt gaccttcccg acaagtgacg ttcccgacga
    14281 gtgactctcc cgacaagtga ctctcccgac aacccgatac aagtgacctt cctgacaaga
    14341 ggtgaccctt ggacgcacag ctctacgaca cggtgatcgt cggaggcggc ccggccggcc
    14401 tcaacggagc tctctacctg ggccgttcac gccgccgagt cctgctgatc gactcgggtg
    14461 acgcccgcaa catggcggcg ggcgtcatgc acaacgtcct caccaacgac ggggcgacca
    14521 tcgccgactt ccgcgcccgc tcccgcgccc agctcaccgc gtacgacgtg acgttccgcg
    14581 acgacgaggt cgtgtcggcc gagagcgacg gcgaccacgt ggtggtcacc accaaggagt
    14641 ccggcacctt ccgcgcccgc accctgctgt acgcggccgg agtgcgctcg gtcctgccgc
    14701 ccgtcccggg cctggcggac ctctggggca gctcggtctt cgaatgcccg tactgccacg
    14761 cctgggaggt ccgtgaacgc agctacgccg tctacggagg gaccgtgccc agcgaatgcc
    14821 tggcctcgac cctgacggtg tggtccgacg acatcaccta cctcaccgac cggcgggagc
    14881 tgccccagga cgagcgggac cggctcaccg cggccggcgt acccgtccgc accgagggcg
    14941 tcagcgagct gaagccgcac cccgagggcg tcgaggtcgt cttcgaggac ggccgttcca
    15001 ccgcctacgg cgccctgttc ctgcacctgg acatcgaacc ccgggtggac ccgctgcgcc
    15061 cctggctcca ggcgccggac ctggagtccg tacagaccga cgaccgcggc cgcaccagcc
    15121 tgccccgcct ctacgtcgcc ggagacctcg gccggaacat gcagcaggcc gccatggcag
    15181 cggccagcgg aggcctcgcc gccatggcca tcaacgccga cctgatccgg gaggaccgcc
    15241 ccggctccct gcccgagcca ccgcccccca ccccggcccg ctgagcagac gcacccctca
    15301 ccacagccac acagcgcacc cacgggagcc cccagcgatg acgtcacccc gcgccgagtt
    15361 caccccgcac atggagcact acaccttcgt cctcgaggac cagccctatc tgggctactt
    15421 ccagtacggc aacgagaaga ccccggtcta caccaccgac cggcacggct tccgggtcac
    15481 cccgggcccc ggcgaactgc gggcgacggt cggcgacgac cgccccgacg gcccggcgcg
    15541 cgtcctcgcg ggcagctccg cggtcttcgg cgtcggcgcc acgagcgacg cggccacgat
    15601 caccgcccgc ctgtggaaca cccacgcccc ccggctgccc tggctgaaca tggccggaca
    15661 gagccacaac tcggcacagg aactgctcct gttcactctc ttccggcacg aacttccgcc
    15721 ggtcgaggac atcgtgctgc tctccggggt caacaacctg gtgctcagcc ggctgcccga
    15781 ggacaaacag ggccgccacg gcgccttctt cgactgcggg cccgcccccg acgtcgtacc
    15841 gccacccgac cagcgcgtca cgcacgccac ggaactgacg atccggcacc tcagcggctg
    15901 gaagctgctc gcggacgccc tcggcgcacg cctgaccttc gtgctccagc cgctcgcgcc
    15961 ctgggtgcgc gaggagccgc tgccccgcga gaagctgctc ttcgacgagc tggacgaggt
    16021 gtccaacttc cgccgcttcc acaacgacat ctccaccatg gcggtcggcc gcgcctacgc
    16081 gcggcggctg gccgacggat gtgcccgcct cgacgtgccc ttcctggaca tgaacgtggc
    16141 actcggcgaa gccgccggac ctgaggactg gctgttcatc gaccgcgtgc actgcaccga
    16201 cctcgggtac gacctggtgg cccggcagct cgcggaccgc ctcgacctgg catgaggagc
    16261 ccctccatgc gcgacgacag cagcgcggca cccgcgtcgg cggcacgccg cctcgcctcc
    16321 tggctgcgcg accggggccg ccccgtgccg cccgccgacg cccagccgga cgaccagtcc
    16381 accaccgccg aaccaccggc accaccgccg acccggctgc ggccgcaacc cgaggacgac
    16441 gcctccgtct acccgctgtt ctgacatggg gaggaccgac atgggcaccg cgcgcgccga
    16501 ccgccgcggc accggcggcg cggagcgccc ggtcctgggc atctccgcct actaccacga
    16561 cagcgccgcc gctctcgtgg ccgacggcgt cccgctcgcg gcggcgcagg aggagcgctt
    16621 cacccggcgc cgccacgact ccgggttccc cgcgcacgcc gtcgcctcct gcctgcgcga
    16681 ggccgggctg cgcctcgacg agctggcggc ggtggcgttc tacgaggacc cggcgctcaa
    16741 gttccgccgc gtgctggcga cctggctcgc cacggcaccg cacggcttcc cggtgttccg
    16801 ccgggcgttc ccccagtggg ccggctggaa gcggcgcgcc ctcgacgacg tacgggccca
    16861 cctgcgcgaa ctggcgcccg gacagacgct gccgccggtg gtggcgtacc ggcaccacgc
    16921 ctcgcacgcc gcgtcggcgt tcttcccgag cccctacccg tcggcggccg tgctgtgcgt
    16981 cgacggcgtg ggggagtggg cgacgaccac cctgtggcac ggccgcggca ccgacctcgt
    17041 cccgctcgcg gaactgcgct tcccccactc gctcggcatg ctctactcgg cgttcaccta
    17101 cttctgcggc ttcaaggtcg actcgggtga gtacaaactg atgggcctcg cgccctacgg
    17161 cacaccgcgc tacgcgccgc tcatccggga gcggctgatc gacatcaaac cggacggctc
    17221 cttccgcctc gatctgcgcc acttcacctt ccagtacggc cggaccatgg tcggccgggc
    17281 cttcgaggag ctgttcgacg gcccgcgccg cacaccggaa ggcccgctca ccgagcggga
    17341 attcgacctg gcggcgtccg tgcagcaggt gaccgaggaa gtgctgctgc ggctggcccg
    17401 cacggcactg gaacgcaccg gcgagcggcg gctgtgcctg gccggcggcg tcgccctcaa
    17461 ctgcgtggcc aacggccgcc tcctggccga cggcgtctgc gacgagctgt ggatccagcc
    17521 cgcggccggg gacgccggcg gatccctggg cgcggccctg gccgagtcgc accgcagggg
    17581 agcgccccga gcccacgtgg cccgcggctc ggacgcgatg gcggggtccc tcctcggccc
    17641 cgcccactcg gaccgggaga tcgcggagtt cctgaccgac cacgggtacc ccgccgtacg
    17701 gctgccggag cggaagctga cggagcgggt cgcggcggaa ctcgcgcggg gcagggtggt
    17761 gggctggttc cagggccgta tggaattcgg gccacgggct ctcggcaacc ggtcgatcct
    17821 cgccgacccc cgcgatcccg ccacccagtc cacgctcaac ctcaagacca agttccggga
    17881 gtccttccgc ccgttcgcgc ccgcggtgct cgccgaggac gccaaggact ggttcgacct
    17941 ggcgcaggag agcccgtaca tgctgctcac cgcgcaggtc gccgcggccc ggcgacgcga
    18001 aatcgaaccc ccggctgagg gagtgaaggg cctggacctc ctgcgcgtgc cgcgctccac
    18061 gatcccggcg gtcacccacg tcgacggctc gtcccgcgtc cagacggtga cggccgagca
    18121 caacccgcga ttccacgccc tgctcaccgc cttccgggac cgcacgggct gcccggtgct
    18181 ggtgaacacc tccttcaacg tgcgcgggga accgatcgtg cgcaccccgc aggaggcgta
    18241 cgcctgcttc atgcgcaccc ggatcgatct cctggtcctc ggcgaccacc tgctggacaa
    18301 acgggaccag cccgagtggc gggaggaggc cgactggcgt gcgacgatcc cgatggactg
    18361 aacggctgcg acacctcggc ctggccacgc tgtacttcgc ggtggtcact ccggccggac
    18421 tgtgcgcacg ggcggtgcgg gacccactgc ggcgctcctg gcacgaccac cgggcgagct
    18481 atctcacccg ctcggacagc ccaccgctca cggatggtcc ggacgcgtcg ccgaagtgag
    18541 cacgacgcgc cgcgtaccaa ggacatgcac gcgggattcg gcccccgtga acccacactc
    18601 cgtcaccaag gcactcgctt cctccgctgt gcgaggcagc gggacatcct cggcgaggag
    18661 ccgggagaag cgttcggagg gccgaaagtg cgtagcgagc ggcagactga aacccacccg
    18721 gccccccgga cgcaccgccc gccgccagtc ggccgacgcc cggcgcccca ggaagtgcag
    18781 cgaagacgcg cacagcacga ggtccagcga accatcggca accggcaacg gcacggcatc
    18841 cccgacccgc cagtcgatcg ccgtgtcggg caccagcccg gcggcacggg cccggcccac
    18901 cgcgatcatc cgggacgaca ggtcgacggc gagaacgggc cgcgcggccc gctcccgccc
    18961 ccgcgcgagc tgcacggcaa cggcccccgc cccacacgcc acgtcggcga ccgcaccgac
    19021 cgctccgggc cccacccacg cgatcagagc ccgcgcgatc tcctcgtgat gcccgtggtc
    19081 gtagccgtcg gccagatcgt cgaagacccc agcgagcgtt gcgcttcgtg tcacgtcgtg
    19141 atcctagcca ggtgtcggcc gctcgatggt gcaggactcg gtctcggggc agcgggcatc
    19201 ctccgcactg cgcgccgccg cacaggcggc caccgtgctg ggcggatgag gccgccgggc
    19261 tccggccacg cccgcggccg tggtccgacg tcgccgaccc gaggctctgc tcggtctgcg
    19321 cgagtcgcag cggatcggcg cgagcgaagt agccctacca cttgtcggcc ccggctgttg
    19381 ccgaggactt cgccaaggac gcgctcacca ggaaacgggt ctcactggga tgtcgcacag
    19441 tccggacttc gccgctgacg aaactgccgt cggggtgggc gtgcggtcga tggcggactt
    19501 cttggccagc cgactccgca ctctcgcctg aaccgcagca tccgaacctg tggcggccgg
    19561 ccgccacacc tcaccggtac gaggccggaa ataggcccaa taggtggctg ttgccccctc
    19621 gcccctgcgc aggagcgatc tcacgtccgt tggggggaga ggaccatcgg cagtgcaccg
    19681 gattcgcagc cactggcgat gcgcaccgcc aggacgggca acacatccac cggcagcacc
    19741 cgcatgagcc ccgccggggc cagggtggag tgcaatgagc gcatccgatg cgcacgaacc
    19801 cgattgcccg acataccctg ggcgacggtt caggattctg cgccaggcgg cagaagtgcg
    19861 gcctgtccga ctgccttaac gtgctgctgc gcgagtgtgc tcccagacaa ccagcccacc
    19921 ctacgggcct gttgcggaag ccgatcgtct gtcagaccta cctgggatgc tccgagcatg
    19981 gagatgacag tgcagctgac gatcgactgc tccgatccgc agagaatggt gactttctgg
    20041 gccgaggccc tgggctacgt gcctgagcct ccgccgggcg ggcacgccac gtggcgtgcc
    20101 tactgggcgg cggcgggggt gcccgaggca gagttgccgg ccggtgccgg ggatgttccg
    20161 gagtcgatca tcgaccccgc ggggcgtgga ccgagggtgt ggttccagca ggttccggag
    20221 ccgaaggtcg ccaagaaccg gtggcacttc gacctcaagg tcggtggggg ccgtgacgtc
    20281 cccctggaca tccgcacaca gcgcgtcaag gctacggtgg aacggctggt caaagctggt
    20341 gccacagtgc tgcggatcaa ggacgagcca gacatggggc tctacgccgc cgccatgcag
    20401 gaccccgagg gcaacgaatt cgacatcgtc tgagggccgt tgcgacggtg ctggtcgcag
    20461 ccactcgttg atggctgcga ccggcacgcg cgtcgtagcg gaaggcgaac tcgtcgaacc
    20521 tcgtggccat ggcccggtgg cgcttgagct ggttgccgcg taggtggaag gacgaggacg
    20581 gctcctcaac cctaggcgct gcgcggtgcg tggcagaagt tgtcctgggg tgggtgcgct
    20641 gtctgctgaa actgcggtaa agtggatctt gagcgcaccg ctggatttgc cggtggtgag
    20701 ttgtgcgttg gtggtccaag gaaagacgcc ccgcttcctg cggggagatg caggtgcaag
    20761 gcctgcccgg cgctccacga agaagacccc cggacctgct gttcaggacc gggggtcttc
    20821 tcgcatctga tcgctgaggg tgtccatccg ccctgatgcg agcaacggcc tccgggttga
    20881 agcccccgat ggagcctggg cggcgaacgc ggcgtggagg aaggcccgtt cgagctgctt
    20941 gttcccgcgc ttggatggtt gttctccgcg gttcgagggc ccggaactgc tggtcgccgg
    21001 ggcgagaccg gcgtaggcgg cgaagtggct cgcggtccgg aaggtgctgc ggtcgccgat
    21061 ctcgatcagg acgcgggctc cggtcctgac gccggctccc ggcatcgatg tcaggacgct
    21121 ggaaagaggt gggccctcca ggagttcctc gatccgcccg gccaacagtg atcattggtt
    21181 gagcaccgcc atcagcgaag cggccgggct cggggcgatc agcgcagctg cctcgcggtg
    21241 ccgggtgcgg gcctccggga gcgcgtcagc ggatgccccc ggccgtccga ggtacgggag
    21301 ttcggacggg cgaaggatct cctcgggcaa gaatcgagca tgtccggcct gtgcggatac
    21361 tgctggagcg gaaagctggc cgtcgccccg gacggaaaag tcttcacgtg cgtcatggca
    21421 cgggactggc cggtaggtga tgtcctcagc caatcgctcg gcgagatcct gcagggcgcc
    21481 gaactcgccc aggtccgccg cgaaatccac gagacggtgt ggttgccggc caccgctggc
    21541 gacgagcgct gcccccagtc ctgcggaccg gacctctcct gcccgtgcga cccactgctc
    21601 tgcgaaaagt gctgcggccc cacgcacctg cagtgaccgg acatggctcg tagtgaagac
    21661 gaccctggag cggccccgta ctctcgtacg gaccgcccat gcttcgaaca atgccctcac
    21721 gctttcccat cctggccccg gggtgaagcg cgccagcaag aagggctgat cgcagccgta
    21781 ctcactgacc tcaccggcca ggacgccccc cccgcaatag ctgccactga cgggtgggct
    21841 cggtgtagtg caggacgagg gaggcctgca cgatcgcggt cgcgcggcga gggcagcagc
    21901 gctgcttggc caggatcctc ccggccttga ggatggcgac gacgcgttcg ccgagtgcca
    21961 gggccgtggc gtggagccca ttgactcatt ccgggtgcgg caggttccac aggtggaggg
    22021 tggtctggtc cttggagacc gtgtaccagg cgccctgccc cgccgatcgg ggaggtcccg
    22081 agacagggaa ggggtaggcg atccggccgc gcaccaccat cgtgtgcggg tcgacaaacc
    22141 agtggcgggg gtcctccaca aagtcctcgg tgccgaccac ggcggtgtcg tcgtagggga
    22201 acgccgccgc ctcgtagtcc caccgaacac ggtcgtcgtc cgagcttgcg ggaaggggca
    22261 cggcttcgtc agcgtccaga tgccgcagtt cgatgccatc ctccgcccgg tgcaggtaga
    22321 gggtccactg ccccaggtcc gtggtcagga agtgctcccc ggacggactc acggcgagga
    22381 ggacttcctc gacgaaccgc tggacggtga ggttcgtgcc gtcccagtgt ccccacagta
    22441 cgggcgagtt ctcctcaccc tcgccgaccg tcagccccat gtaggccggg ttcggatggg
    22501 ggaagtggag ggagcccgat cccacggtca tcgtgtcggc ccgggtcagt accgtgccgt
    22561 cggcggggtc gaggatcagc cattcctcgt tgacgtcgcg ccccgcgcgg ttgcggacgt
    22621 gtgcccacag gagcttgccg tccgcggaga atgccgccga gccgaggtcc gcgtggccgt
    22681 ggtggtagtc gtcggcgtac tcggagaacg aggcatgggc cccggtgcac acggcggggg
    22741 accaacaacc gtgccggatc tcccaccgca cggcaccggt cgaatccacg gctcgcaacg
    22801 cgtgcacgcc ggcgaacacg gcaacatcac ccgtgggcga gactgccacc gagccgtacc
    22861 ggcggggcca gggcgcgggg aagcggatct ctgtcccctc cccgtccagg tcgcggacgg
    22921 ccagctcggt gtccccgcgc tgcaccagca gcctgcgctt gggccagtgc agcacctggg
    22981 gggcgtccgc cgatgcgggg tcgagcgggg ctgcggcggt ggccacgagc ccggcagcga
    23041 cctgggtggg acccccgtga agagcatcgt tcggcatcgt cgcatgcttt cacactcgtc
    23101 ggatggtgca gctgacctga agtcgcccgc tttgatcagc tttttgcatc gggtcttcgg
    23161 tcttactttg cgagccccgg catccggtac gttgccgtga gtaggagccg gttcacctcg
    23221 aacagcgccg ccaaggaatc actgagccgt cttcctcctg agtagcggct ggtctcgacc
    23281 tggtgcagga cgaggacggc ccgcacgacc gcggtcgtgc ggcgggggca acagcgcagc
    23341 cgggccagga tcttccatgc cttgagcgtg gcgatggccc gttcgccgcg ggcccggatg
    23401 cgtgcgtgtg cgcggttgac ggccttctgc cggcgggaca gtttcggccg gtaccggtgg
    23461 cgctttaacg gcgtgcgcac gctcccaccg gctgcctggt agcccttgtc tgcgaaggtc
    23521 atcacgtcgg cgatggtgag cgcgtcgatg atgccgtgag cgcgggcggc gctgaggtcg
    23581 tgggaggcgc cgggcagcgc tggcgaggcc cagaccaggc gacctactgc gtccgcgatg
    23641 acctgcacgt tcatgccgtg ccgcttatgt tttccggagt agtagggctt ctggtcggct
    23701 acacggtcga tcgggatcag tgtgccgtcg aggatcgcgt gcgccagctt gcggatacgg
    23761 tccatgacgg tgtccaggtc gtccgcggct gcggcgagca ggtcgacggc ttcacggacg
    23821 tagcgccagg cggtggtgcg ccgatgccga acccggctgc caggcgggtg taggtgtcgc
    23881 cgttgcgcag gtgagcgagg gtgagcaggg cctgtcggcc ggggtcgagg cgtcgccacc
    23941 gggatcgacg ctggtggcgg tggttgcgga tgcgctcggc aaggtggttc agggttcggc
    24001 tgggcagcgg gatcgtggcg gggtaggaca gcacggcgag gctcccggtc ggggcatcgg
    24061 atcttgaccg actgctgtct tacctggagc ctcgccctca tcggtctctg ggtccccgac
    24121 gcccaccgtg accagcatga tcacgatgaa tagggctcag tgcataaccg tctggccaag
    24181 cacttcacat tgaaacgatc agtaaggttc cgagtcgcct cgaacgcccg tcgctggccg
    24241 acgacgtcgc gggcatcttc ggtacgtaga tgcagtggtt ccgcagtacg tcggtaacag
    24301 gggacgatgc ggctcgatcc gtgcccggcg atctcagcag ttcgcgctgt agcggatgca
    24361 tccgggtggc gaggtgtggc tgtcatccca ctcttgctgc gccgctgtga gcgatccgcc
    24421 tgccaggagg gccaccagca ggtgtgtgat caccgtccag cgggcacgga agagtgccgc
    24481 gagaactgcc aggacgagta cggcgatcag cagcatccgt acccgcccga tgtgcgcgag
    24541 gccggccgcg tcgatccgtg cttgctcgcc ttgtgctgcc catacctcca agccgtagcc
    24601 gtatgtccag tccagcacga gccacgcggt ctccagcagg aacagcggaa tcgccagagc
    24661 aaggtccacg cccaggcgtg ttcgatgcgc ccaggggcgc cggcgcacct gggccggaag
    24721 ggcgtcagtc atgggtgcag ggtgccgcgg ccggtggtga tgcgcatgag tacctgtact
    24781 caactatggc caggcggagc ggcagatggg tgggcgggtg acggtccgct gcgcaccatt
    24841 gccggtgccc tcaccaatgc gagcctgggt gccggccgta cggggcaggg acgtatgaac
    24901 tgtggtcgtc ggcttgccca gcgccgagag cggcctgagc gtcctgaccg tttctcctcg
    24961 tcggcggcgc gtgggtggta ggaagagggc ggctccccta ccccaggcgt tgcgcggtga
    25021 gtggcagaag ttgtcctggg agagggtgcg ctgtttgctg cgactgcggt attatggatc
    25081 ttgagcgcac cgctggattt gccggtggtg agttgtgcgt tggtggtcca aggaaagacg
    25141 ccccgcttcc tgcggggaga tgcaggtgca aggcctgccc ggcgctccac gaagaagacc
    25201 cccggccctg ctgttcaggg ccgggggtct tcttggctcc ggccgctggg ggagtgtctg
    25261 cccgtagtcg ttgcggttgt tcttcgggaa gtgggtctgg ccgtcgagat tgtcgcggcg
    25321 cgggctgtgg atggagcggc cgctgagtcg cgtcccgccc tgacccggtc ggcgggcagc
    25381 gtctgcgtca actgtcccgc ccagagcccc gaccagttgg acggctgctc cttggcgccc
    25441 gatgttcagc acgcccgccg cgtacccgat tcattggcga ggacccctac ctcgtcaaag
    25501 tctgtgacgg ccctgccacc cagatcgtcg tctccgaccg ctcgacatgg gcgaggaatg
    25561 gatagccaaa tcccgggagc atctgatggc cgccaaggcc gctctcggcc ttggcgtaga
    25621 ggttcaccct ggcacaggca cgtgaccgcg agctcgcccg ctctgcgccg cagggccgcc
    25681 gcaccgtcac cctgggcggc catgccccat gccaggggcg agacacggcc agccgctcac
    25741 gtgagccgac ggcggtcttg cgacccctcc caggcgccgg tgcgggccag cacggcgacg
    25801 cggacctggc acggccgctc ggcggtggcg ccggcgcttc agcggtgctt gatgccggct
    25861 tgggcggcgg gggcgagggt gggttcggtg acgggagcgt cgcccgtagg gaccccgtca
    25921 tgtcgaagcc ccgtgcgaag ccgcccgcga agggggcgtg agcgggccgg tcacggcatg
    25981 gagggctgtg cggcgaagac cacggcggag ctggagccgc cacgaggagc gcgcggggac
    26041 ccagggtggg cgggccgtag cggagatggc tctcggtatc agtgccgaca gccacgttgt
    26101 gcggcgggac gatatgaccg cggggcgcct ggaggagggg cggggctcgg tgtcagcgct
    26161 cgatgtcggc cagcgaggcg gccgcgtccc ggtcctggct cgccgcactt tggccggcac
    26221 agcgaacgac cgcggccgcg ggcggggcgg gaaatcgatt ggcggcggcc gtgcctgcgt
    26281 ctaccgtcgc ccgtgatgga gatgtccttc cggaagctgc cggacaatca gcatgagatt
    26341 ctggttcgcg cccgaaaagg gccggacgtc aggttgcctg cccagcccgt cggcccgaac
    26401 atgccgcacg acctggtcca cgccgtcgtg gagaccgccc tcggcatcaa tgacggcttc
    26461 tggggggcga tggcgcgcgg ggccactttc caagggttcg aactcctcac gccgggtcgg
    26521 catcgccgct ccgggatgaa agtgctacgc cggggcggcg acgcggtgat ggctgccgag
    26581 ctctctgtga actgggccta ccgggtgtgg cggggcctct ccacggaggg gcgcggcgtc
    26641 ggcccagctc ccctggactc ggacgcgctg gccaggacac taccgcgcct gaacgcagcc
    26701 gccacccgct ggaccgcagt cccccaaggc ggggaactcc tctggcgctg gggctcagac
    26761 cactagaagg aacggggtgg tgaggctgca caggatggtg gtgctgccga tccgacgcac
    26821 cgactcacct ggtcacacac cgcttcaccg ccaccctgca tcgccttacc cctaaacggc
    26881 gcctacgctc gcgccgcccg ggtcggctcc aggaggagca cgggttggct attccactca
    26941 tcgcatgaag cccgaggaat ggatcgccca gcaccctggc acgccccggg cctacgtcaa
    27001 gccactgcag gtgaggctca acccggacca cggcgtaagg gtgcggggag ctggacgaga
    27061 gatacgactt ggtgtgctcg cacggtgctc gcacggtgct cgcgcggcag gggaaaggac
    27121 cacctatcac accaacgtcg accgcctcgt acagaattcc gtcagcagcg cctataccgc
    27181 gaaagctggt ccggctcgtc gctgaccgcc aggttctcag gcaggatgga gagcgggagg
    27241 gctggagccg cccttggagc gggctggaga acgcgatggc gtccggtgac gagtgggacg
    27301 acgcgacgag gcggctcggt gacgagcccg aggggggacg cgatgacggc acccgacgca
    27361 cccggtacgg ctgatgccga gcaggtgaac gccgcgatgt ggcacaccta cggagcgcac
    27421 cacctcgacc gggccacgcc cctgcccgag gtggacgaga tcgcctgggg cccggcggga
    27481 acagggccgg gggacgccgt cctcggcgac ctgaggggcc tgcacgtgct ggacctgggc
    27541 tgcggcccgg gccggcacgc cgctcacgtc gcccgcaccc atcacgccac cgtggacgcc
    27601 gtcgacttct cacgaactca gatcgcccgc gcacgggcgc gctatggcga cctgccgggc
    27661 ctgcgattga tccaggccga cgccgtcggg cacctgcacg cttcggcgcc gtacgacgtg
    27721 atctactccc tgtccgccgt ccacttcatc gacccgcacc ggttgctgcc agccctggcg
    27781 gcggccctca ggcctggcgg acgccgggca catgtgggta ctcacgacaa agctgtggat
    27841 ggacctgctc gcgcagcacg ggctgcgcac cgaggaggtc accgtgcttg acgcgcccga
    27901 ggagggcaac caggcctcct accggctctt ccaggtccgc aggccggccc ggatcacctc
    27961 tcgtccccgt actgcccatc cgccggtcgc acacgcggca gtcggcgtcg gcgcggtgct
    28021 ggtgggaccg cgcggtctgc tgctcggcca ccaccggaaa gggaccgtcg agctgcctgg
    28081 cggcacagtg gagccgggcg agtcgctgga ggagacggtc gtgcgcgaac tggccgagga
    28141 gaccggcctg cacgcggacc cggccgacgt gcgtctgctg ggcatgctcc tcgaccaggt
    28201 cggcgacgtc gtccgcatca cgttcggcgc gctcgtcacg cggtggagcg gggaacccgc
    28261 cgaccagccg ggcgagcagg tcggcggctg gggatggtgg ccgctggacg cgttgccgcc
    28321 ggacctgttc gagtgcagcg cccagatcct gacggcctgg c
//
