LOCUS       NZ_LIVZ01000012        21114 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0107 scaffold12, whole genome shotgun sequence.
ACCESSION   NZ_LIVZ01000012
VERSION     NZ_LIVZ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0107
  ORGANISM  Streptomyces sp. TSRI0107
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 346933)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 346933)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905845.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,745
            CDSs (total)                      :: 7,667
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 200
            CDSs (without protein)            :: 200
            Pseudo Genes (ambiguous residues) :: 0 of 200
            Pseudo Genes (frameshifted)       :: 85 of 200
            Pseudo Genes (incomplete)         :: 158 of 200
            Pseudo Genes (internal stop)      :: 13 of 200
            Pseudo Genes (multiple problems)  :: 51 of 200
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:19:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 83571
            Orig. end                         :: 104685
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVZ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21114
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="melanin"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..21114
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    955..970
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            1424..2650
                     /locus_tag="AMK31_RS29585"
                     /old_locus_tag="AMK31_29105"
     CDS             1424..2650
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662958.1"
                     /locus_tag="AMK31_RS29585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29105"
                     /product="DUF6777 domain-containing protein"
                     /protein_id="WP_073943753.1"
                     /transl_table=11
                     /translation="MSVEPPNSGRPTGPPSGPLSGRAQPPSGPPPPPPPPPPGRGPAPD
                     HEPREPGRPWWKSVPRVATIAVVVAALATVGVLLTRGDSGTGGSREVFLQAANSRGPDP
                     FTDSTAQGTSTSPATPTTPPTTALTPSETVTAGENRVRGYNGGTPGVYGGTRDVAACDV
                     ELQITYLRENPDRNRAFAAALKLDPDDVPAYLRGLTPVLLRMDTRVTNHGYRDGEADPY
                     QAILQSGTAVLVNDRGLPRVRCACGNPLTNPLQQHTGYERIGDSWPSFDPAKVIVILPA
                     AEPVKTFVLRDIENGGWVARARGDDGDRDVPTKPPKIPPTPTDISPRPPSPDTGSPTGE
                     KPSSESSPRPDSSPTPPPPSPPTSPDTSTSEPPQSPPASTSVPDVPDSITQSTPPTSLP
                     VPGTSVPSV"
     gene            2742..3197
                     /locus_tag="AMK31_RS29590"
                     /old_locus_tag="AMK31_29110"
     CDS             2742..3197
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971866.1"
                     /locus_tag="AMK31_RS29590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29110"
                     /product="ATP-binding protein"
                     /protein_id="WP_073943754.1"
                     /transl_table=11
                     /translation="MIEHRDGTVVPTSIDVPVEPLRRTAHYTGEPGCIAEAREFAAQFV
                     NQLRTEWCAAIGARAEEALLLVVSELVTNADRHSEGPYILDLSGTDGSVTVSVYDSSDA
                     LPRRFPRDPERIGRHGLEIVHALADRVAVERVPVGKRVWAVVALADG"
     gene            complement(3260..4153)
                     /locus_tag="AMK31_RS29595"
                     /old_locus_tag="AMK31_29115"
     CDS             complement(3260..4153)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009193317.1"
                     /locus_tag="AMK31_RS29595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29115"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_073943755.1"
                     /transl_table=11
                     /translation="MDTATAVTGSDAPLVEESARAGTTSEPEPAVVDPRSVAPRDAREL
                     SRQFFRRLAELEEGTHEYQYARNTLIEMNISLVRFAAGRFRGRGDDMEDIVQTGMIGLI
                     KAIDRFDLSREVEFTSFALPYIVGEIKRFFRDTTWAVHVPRRLQELRVELAKAREELAS
                     RLDREPTVAELATLMNISEDQVIEGQIAANGYNSSSLDAALTGDGPEDGEAVLADFIGV
                     EEHGLRLVEDFQSLAPLMAELDERDRRILHMRFVEEATQAEIGEQLGCSQMHVSRLLKR
                     IIVRLREGMLGELDRV"
     gene            4459..4896
                     /locus_tag="AMK31_RS29600"
                     /old_locus_tag="AMK31_29120"
     CDS             4459..4896
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117992.1"
                     /locus_tag="AMK31_RS29600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29120"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_073943756.1"
                     /transl_table=11
                     /translation="MTNQAPNEARVIPLRPRTARPARPAAGTASPAPARPAPPREPAAK
                     EPLWRDLVGDVLRRERLAQERTLKDVADAARISMPYLSEVERGRKEASSEVLAAAAHAL
                     GLGLGDLLGLAQRELVRVTSRHSTTGRRPAGSSYDGLCLAA"
     gene            complement(4918..5520)
                     /locus_tag="AMK31_RS29605"
                     /old_locus_tag="AMK31_29125"
     CDS             complement(4918..5520)
                     /GO_function="GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971863.1"
                     /locus_tag="AMK31_RS29605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29125"
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_073943757.1"
                     /transl_table=11
                     /translation="MGSYTIPHVVERTPQGERSYDVFSRLLSERIIFLGTEIDDGVANV
                     VIAQLLHLESAAPENEISVYINSPGGSYTSLMAIYDTMTFVRAPISTFCVGQAASTAAV
                     LLAGGDAGRRFVLDHARVLLGQPASGGRQGTVSDLALQAKEMVRIRSQVEEVLARHTGH
                     DIATLRADMDRDKVFTAREAVAYGLADEVLSRRLVTV"
     gene            complement(5523..6161)
                     /locus_tag="AMK31_RS29610"
                     /old_locus_tag="AMK31_29130"
     CDS             complement(5523..6161)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662962.1"
                     /locus_tag="AMK31_RS29610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29130"
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="WP_073943758.1"
                     /transl_table=11
                     /translation="MTQLTVLTPRAEESDTPRTRFDDHLAAQLLGQRIVLLGTQVDEVS
                     ANRVCSQLLILSAEDPRTDISLFVNSPGGSVHAGLAIYDTMRLIPNDVSTLTMGFAASM
                     GQFLLSVGAPGKRYALPNARIMMHQPSAGIGGTTADIEIQADNLEFTKRTIERITAEHT
                     GQSPETISRDGDRDRWFTAEEAREYGMVDRVVESFTDVLPAATRRRTGL"
     gene            complement(6272..7474)
                     /locus_tag="AMK31_RS29615"
                     /old_locus_tag="AMK31_29135"
     CDS             complement(6272..7474)
                     /NRPS_PKS="Domain: Abhydrolase_1 (100-207). E-value:
                     1.1e-13. Score: 43.4. Matches aSDomain:
                     nrpspksdomains_AMK31_RS29615_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033136.1"
                     /locus_tag="AMK31_RS29615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29135"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_079186983.1"
                     /sec_met_domain="PF00561 (E-value: 7.9e-11, bitscore: 36.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSSPADAPRPFRLAVPDGDLADLHDRLDRTRWPDQLPGVGWAY
                     GVPADYLRELVRYWRHEYDWRAAEARLNEWPQFTTTIDGANVHFAHIRSPEPDATPLIL
                     THGWPGSIVEFLDVVGPLTDPAAHGGDPADAFHVVLPSIPGFGLSGPTTEPGWEAGRVA
                     DAWAELMRRLGYERFGAQGGDWGAAISRELGRARPDRVVGVHLNLLPGAQAVTEPTEEE
                     LAALGPEERERTLTSWRRWDAWSREGTGYAVLQATRPQTLAYALTDSPVGQLAWITEKF
                     REWTDSEELPEEAVDRDRLLTNVMLYWLTGTAGSSARVYYERAHATGRAAAPAEPSTAP
                     TAVALFPAELQLPLRHKADRTENIVRWTEFDRGGHFAAMEEPDLLVADVRAFFRQLRET
                     G"
     aSDomain        complement(6854..7174)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS29615_Abhydrolase_1.1"
                     /evalue="1.10E-13"
                     /label="AMK31_RS29615_Abhydrolase_1.1"
                     /locus_tag="AMK31_RS29615"
                     /protein_end="207"
                     /protein_start="100"
                     /score="43.4"
                     /tool="antismash"
                     /translation="PLILTHGWPGSIVEFLDVVGPLTDPAAHGGDPADAFHVVLPSIPG
                     FGLSGPTTEPGWEAGRVADAWAELMRRLGYERFGAQGGDWGAAISRELGRARPDRVVGV
                     HLN"
     gene            7597..8079
                     /locus_tag="AMK31_RS29620"
                     /old_locus_tag="AMK31_29140"
     CDS             7597..8079
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138605.1"
                     /locus_tag="AMK31_RS29620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29140"
                     /product="VOC family protein"
                     /protein_id="WP_073943759.1"
                     /transl_table=11
                     /translation="MTTDGFTTCLWFDGQAEEAAHFYVSVFKNSGVGEVTRYPEGGFRP
                     AGTVLTVEFTANGQKFVALNGGPEFKFNEAISFQILCADQEEVDHYWTKLTEDGGEPGP
                     CGWLKDRYGVSWQVVPERLTAMIGDPDPEKAARVTKTMMAMGKLDIAALDRAYAGE"
     gene            complement(8084..9019)
                     /locus_tag="AMK31_RS29625"
                     /old_locus_tag="AMK31_29145"
     CDS             complement(8084..9019)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982581.1"
                     /locus_tag="AMK31_RS29625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29145"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_073943760.1"
                     /transl_table=11
                     /translation="MRGRWVAGWTLAGAMLLGGCGDPTGDPTGDPPRPPAAPVAPGTSV
                     TPEASAPTRQQAPAAPARPPVVLYLGDSLAMENQRVLGRELRRDLRADYTSAPYSGTTL
                     CDYLEGTGERSLVPDADKAAALVRSVRPDVVVLQFWGNAWGYTPCMDGITYGAAPQRYL
                     ERYTADARRLAGQITGAGGQSPPAIVWVLQGPDPITPERVRKVNAVYEELAAASGEPVA
                     DAGRAVSPASGRYTWARFLPCTAWERAHSGYCTEPGRDRTALHRDDDHLHFCLAPTTST
                     PKPCPVRSPGVLRIAREITRVVGAAARGGG"
     gene            complement(9093..9968)
                     /locus_tag="AMK31_RS29630"
                     /old_locus_tag="AMK31_29150"
     CDS             complement(9093..9968)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117983.1"
                     /locus_tag="AMK31_RS29630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29150"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_073943761.1"
                     /transl_table=11
                     /translation="MTIAPHTRTTTAVPTQSTYQNRVAEYWNAEENPVNLELGKIDDLY
                     HHHYGVGQADRSVLDEPDPDRRRARVTAELHRLEHAQAELLAAHLGPLSPTDRVFDAGC
                     GRGGGSVVAHLRYGCHADGVTISAKQAEFAGAQARKRGIDDKVRYHHRNMLDTGFPSGA
                     FAASWNNESTMYVELDLLFAEHARLLRRGGRYVVITGCYNDTYGQASREVSLINAHYIC
                     DIHPRSAYFRALARNRLVPVHVEDLTEAAIPYWELRKEADHLVTGIEDTFLTAYRNGSF
                     QYLLIAADRV"
     gene            complement(10001..11056)
                     /locus_tag="AMK31_RS29635"
                     /old_locus_tag="AMK31_29155"
     CDS             complement(10001..11056)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987926.1"
                     /locus_tag="AMK31_RS29635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29155"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_073943762.1"
                     /sec_met_domain="T1TS (E-value: 1.7e-60, bitscore: 199.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGSPPVTGPSPFRPPGPPSLAATLRARRTGAIPGLRHRPAVPAD
                     PEKAAEVDRRLEAWARELELFPPEWTGDFTGFQFGRAVALQHPGALDLDRLTAAGKLLL
                     AENIVDDCYCEDRGGSPRGLGGRLVLAQSALDPYHGTPELEARWRHGMEADGSLRSYHW
                     ALKDYAAFATPSQVSRFVHDVARLHLGYLGEAAWAETRYVPRVWEYLVMRQFNNFRPCL
                     SIVDAVDGYELPEALYARPEVQRVTALACNATTLVNDLYSFTKELANDPDHLNLPQVIA
                     RNERCGLKAAYLEAVEIHNRIMDAFEEESAALSAGNPLLARYLAGLAAWVSGNHEWHAT
                     NTHRYHLPDYW"
     cand_cluster    10737..21114
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    10737..21114
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[15736:16114](-)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(15737..16114)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     gene            complement(11053..12477)
                     /locus_tag="AMK31_RS29640"
                     /old_locus_tag="AMK31_29160"
     CDS             complement(11053..12477)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003963.1"
                     /locus_tag="AMK31_RS29640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29160"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_073943763.1"
                     /transl_table=11
                     /translation="MSTPDSATGPATDEPVPEPTSLSTLAARQLTTTTKSEPQMQAITS
                     RWLLKTLPWVDVKGGAYRVNRRLQLRLGRGRVQFEQNGADDVRVIPETLTELPVLRGYS
                     DTEVLRGIATRFQVREVRAGEVLFEAGQPVTEAYLVAHGRFTRYTTGKYGGEEVIDVVT
                     DGEGLGDEAVGRDDPLWLSSVRADTAGTVLALPWDTLEEFADRAPSLAAHLSAYAERQS
                     RPMNRKGEADVPVQAGHVGEPVLPGGFVDYELTPREYELSLTQTVLRVHTRVADLYNDP
                     MNQTEQQLRLTIEEIRERQEWELVNNREFGLLHSADYGQRISTFSGPPTPDDMDELLSM
                     RRKTRLFLAHPKAIAAFFRQCNRRGLVPGTVNVDGHEVPAWRGVPIFPCGKIPVSERHT
                     SSIIALRTGEADQGVIGLYQTGIPEEYQPGLNVRFMGIDSTAIMSYLVTAYYSLAILVP
                     DAAGILENVQIGRMPE"
     misc_feature    12611..12624
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            12803..13612
                     /locus_tag="AMK31_RS29645"
                     /old_locus_tag="AMK31_29165"
     CDS             12803..13612
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031563.1"
                     /locus_tag="AMK31_RS29645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29165"
                     /product="VOC family protein"
                     /protein_id="WP_073943764.1"
                     /transl_table=11
                     /translation="MAVKPEGHPCWADAMFTDLEGAKSFYGEVLGWTFGESSSEHGNYT
                     EAYRDGKAVAAIVPPTPGQEGQDEQSQWCLYLASPDAAATAAKIRDNGGELLMEPMTVG
                     DYGTMCLARDPSGVVFGVWQAGSHEGFQAPMDQPGAFCWAEVFTREPEKSDAFFPAVFP
                     YTARQMEDDGVDFRIFNVGDAPVLGRMRMTDDFPPEVPPYINVYFSVADCDEAVAKATK
                     LGAVLRFGPMSSPFGRFAALTDPQGANFSVIDTQTTEGDMPELTDVS"
     gene            13661..14347
                     /locus_tag="AMK31_RS29650"
                     /old_locus_tag="AMK31_29170"
     CDS             13661..14347
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971859.1"
                     /locus_tag="AMK31_RS29650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29170"
                     /product="ribonuclease H"
                     /protein_id="WP_241842753.1"
                     /transl_table=11
                     /translation="MRERVVAACDGASKGNPGPAGWAWVVADETETPDRWEAGPLGRAT
                     NNVAELTALERLLAATDPAVPLEIRMDSQYAMKAVTTWLPGWKRNGWKTSAGKPVANQD
                     LVVRIDELLDGRSVEFRYVPAHQVDGDPLNDFADRAASQAASVQQPAGSGLGSPEPPSA
                     PDAPPAKAPGRRSPAARKKSGGSSRTIKAKFPGRCLCGRSYAAGEPIAKNAQGWGHPEC
                     RTAAAG"
     gene            complement(14360..14809)
                     /locus_tag="AMK31_RS29655"
                     /old_locus_tag="AMK31_29175"
     CDS             complement(14360..14809)
                     /NRPS_PKS="Domain: Polyketide_cyc (9-128). E-value:
                     1.9e-17. Score: 55.7. Matches aSDomain:
                     nrpspksdomains_AMK31_RS29655_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468324.1"
                     /locus_tag="AMK31_RS29655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29175"
                     /product="SRPBCC family protein"
                     /protein_id="WP_073943766.1"
                     /transl_table=11
                     /translation="MSQVEESIEVAVPVHTAYNQWTQFETFPEFMSGVERIEQRTDTLT
                     HWVTKVDGVRREFDAEITEQLPDERVAWTTVAGDARQAGVVTFHRLDDDHTKVMLQMEF
                     HPDGVAETVGDKLGFVKRQTKGDLERFKRFIEERGQESGGWRGVV"
     aSDomain        complement(14426..14782)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS29655_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="1.90E-17"
                     /label="AMK31_RS29655_Polyketide_cyc.1"
                     /locus_tag="AMK31_RS29655"
                     /protein_end="128"
                     /protein_start="9"
                     /score="55.7"
                     /tool="antismash"
                     /translation="VAVPVHTAYNQWTQFETFPEFMSGVERIEQRTDTLTHWVTKVDGV
                     RREFDAEITEQLPDERVAWTTVAGDARQAGVVTFHRLDDDHTKVMLQMEFHPDGVAETV
                     GDKLGFVKRQTKGDL"
     gene            complement(14881..15705)
                     /locus_tag="AMK31_RS29660"
                     /old_locus_tag="AMK31_29180"
     CDS             complement(14881..15705)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126207.1"
                     /locus_tag="AMK31_RS29660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29180"
                     /product="tyrosinase family protein"
                     /protein_id="WP_073943767.1"
                     /transl_table=11
                     /translation="MTVRKNQATLTADEKRRFVAAVLELKRSGRYDDFVTTHNQFIVSD
                     TDNGERTGHRSPSFLPWHRRYLLEFERALQSVDASVALPYWDWSTDRTVRASLWAPDFL
                     GGTGRSTDGRVMDGPFAASAGNWSINVRVDGRTYLRRSLATSVRELPTRAEVESVLAIP
                     TYDMAPWNSGSDGFRNHLEGWRGVNLHNRVHVWVGGQMATGMSPNDPVFWLHHAYVDKL
                     WAEWQRRHPDSGYLPAAGTPNVVDLGEKMKPWNDTAPADLLDHTAHYTFDTD"
     gene            complement(15737..16114)
                     /locus_tag="AMK31_RS29665"
                     /old_locus_tag="AMK31_29185"
     CDS             complement(15737..16114)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138613.1"
                     /locus_tag="AMK31_RS29665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29185"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_073943768.1"
                     /sec_met_domain="melC (E-value: 3.3e-53, bitscore: 173.9,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELSRRRALTAAAALTAAAGGATALGAAPQAIAADHGDHGAPQS
                     FDEVYKGRRIQGRPAGGGHQHHGGGYAVFIDGVELHVMRNADGSWISVVSHYDPVPTPR
                     AAARAAVDELQGARLLPFPAN"
     misc_feature    complement(16217..16233)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.53"
                     /tool="antismash"
     misc_feature    complement(16218..16232)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            complement(16439..18133)
                     /locus_tag="AMK31_RS29670"
                     /old_locus_tag="AMK31_29190"
     CDS             complement(16439..18133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374214.1"
                     /locus_tag="AMK31_RS29670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29190"
                     /product="cholesterol oxidase substrate-binding
                     domain-containing protein"
                     /protein_id="WP_073943769.1"
                     /transl_table=11
                     /translation="MTDPWSRRGFLRTTAALAAAPALAVADPAAAAEELPGFPAEVPLY
                     RTGYRNWTGEITATGLWACAPARAEQVAEVVNWAWRAGRRVRARGASHGWSPLTIPEGT
                     PPDAPVLLVDTAPHLTGLALESPSSVRAGTGVTLEALLTFLEEHGLGLTAAPAPGVLTL
                     GGALAIDAHGTAVPADGEARRDGHTFGSLSNLVLSLTAVVWDEAGGAYRLRTFRRDEAD
                     CAALLAHLGRGFVTEVVLRVGADTRLRCVSRTDIPAGELFAAPGRGGRTLASFLDRSGR
                     AEAIWFAFTEHPWLKVWSVAPTRPAGSREVTGPYNYPFSDSLPTPVADLVGRLVAGAAW
                     YLAPALGVAQYEAAVLGLAATGSADIWGPSKNTLLYLRPTTLRVHTDGYAVVTERARVQ
                     EVVAGFTAYYRGLLTAYAARGRFPVNGSVEIRVTGLDDPADAGVDGARAPLLSALRPVA
                     GRPEWDTAVWLNVLTLPGTPSAEEFLRELERYVLGTYDGGGTGLARVEWSKGWGYTGRA
                     AWSDPEVVERAVPASFGDGAWTRAAGILDRLDPHHVFGNAFLDRLLP"
     misc_feature    complement(18243..18258)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            18270..19253
                     /locus_tag="AMK31_RS29675"
                     /old_locus_tag="AMK31_29195"
     CDS             18270..19253
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433219.1"
                     /locus_tag="AMK31_RS29675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29195"
                     /product="aldo/keto reductase"
                     /protein_id="WP_073943770.1"
                     /transl_table=11
                     /translation="MEERVFDRWGQRASVIGLGTWQLGADWGDVDDKEALTVLEAAAES
                     GVTFFDTADVYGDGRSEQTIAAFLSGRPDLHVLVATKMGRRVDQIPENYVLDNFRAWND
                     RSRRNLGVDRIDLVQLHCPPTPVYSSDEVFDALDTLVAEERVAAYGVSVETCEEALTAI
                     ARPGVASVQIILNPFRMKPLRQVLPAAREAGVGVIARVPLASGLLSGKYTKDTVFPEND
                     HRTYNRHGESFDQGETFSGVDFATGVEAAAEFAALAPEGYTPAQLALRWIAQQPGVTTV
                     IPGARSPEQARANTAAAHLPPLPDATLDAIRDLYDRRIKDQVEGRW"
     gene            19436..19888
                     /locus_tag="AMK31_RS29680"
                     /old_locus_tag="AMK31_29200"
     CDS             19436..19888
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117969.1"
                     /locus_tag="AMK31_RS29680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29200"
                     /product="DUF6328 family protein"
                     /protein_id="WP_241842763.1"
                     /transl_table=11
                     /translation="MWVELIQEVRVAQMGVQILFGFLLTVVFTPVYRELPDTDRTIYIV
                     TVVLGAAATGALIGPVSLHRLVSGRRIKPQAVSWASRMTIVGLILLLATTTASLLLILR
                     VATHDDFVPWLVTGVLLWYLLCWFGIPLWTRHRYTSRGEPPLSPRR"
     gene            complement(19872..20297)
                     /locus_tag="AMK31_RS29685"
                     /old_locus_tag="AMK31_29205"
     CDS             complement(19872..20297)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971854.1"
                     /locus_tag="AMK31_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_29205"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_073943772.1"
                     /transl_table=11
                     /translation="MNSFVHRTLVMQLQAGTSDRFPVLAHLRYDAEDPFAVTMVFSHDG
                     RVLARWRLDREMLADGLCRPVGVGDVRMRPASTDRWEELRLDFFGDPRADGGHHHATVF
                     AWAPAVAAFLRDSHAVVAPGRERIRVDDFLAEVIAEG"
     misc_feature    complement(20442..20456)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
     misc_feature    20980..20994
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
ORIGIN
        1 gggacctcgc cgtgccggtg cacccggcgg gcgaggagcg cgccgaggaa accggtgacc
       61 agcccccaca gcagggcgag tcccagcgcg ccccacaggc gcggatgcag gaacagctca
      121 ccggagagct cgccgcccag gtcgccgatg cccagcaccg acaggccgaa ggcggcgtcg
      181 atccggcaga ccaggcagat catgagaacg gtgagggcga gcgcgaccgc catgtgcagc
      241 gcgtgctgcc aggcgcgcac ccgcgcgggg gagcgggccg ccatcacgaa cgcggccgcg
      301 atcagcagca ccgcgtccac caccaccagc caccacaccc ggccgtcgtg ttcggacagc
      361 gtgcccaggt tgacggtgct gacgtccgcg gagcgcatca cctggtccag cacgttcggc
      421 atcggcagcc cgaacggccc ctccacatgg ccgtcccagg tggcgcccag tccgatggtg
      481 agcgccagcc acgtcaggtt cggcaccccc agcaggatca ccgccagcgt ctccgccgcg
      541 tgcccccgcg tcaccgcgac gaccaggccg atcaagatgc ccagcaccac gtacgccagc
      601 agcagcacga ccatcgcgta cgccgccgga cgcaccgact gctggaaccg cagcagccgc
      661 cccggcagcg gcgccccgcg cgacaccagc agcgccagca ccagcacccc ggccagccac
      721 agcaacccga acaccagggt caccggcaca tcggtggtga agcccacctt cggttcgatg
      781 ccgaacagct cgccgatgtc gctgatcgcg ccctcgccga gggagatggt gaaggtgtgc
      841 cgggccgcga gggccagccc gagcagggcc agcagccaca gcacggcgat ccgcgccgcc
      901 cagcccagca gttccccggc cccggcgacg gcccggtgcc gcagcggcca caggaagccg
      961 gcggcgaaca ccagcgcgcc gacgagcgtc acggacagcg gaatcaccgt caggccgccc
     1021 tcgacacccg ccagttcacc ggcgctcccg gacaactcga cactgccgcc gacggcggtc
     1081 accaccgtcg ccgcgaccac cttgggatag gcgccgtcgg gcacgtcggt ggccccggcc
     1141 gcccacaggc ccagcgctgc gacgacggcc atggcgagcg ccccggcgag ggtcacggcc
     1201 agcgcccgaa cccacccgcg gagggcgacg gcctggccga cggagatacg caggctcaca
     1261 tggccacgct aatcagcaca cggcgccctc gcccgccggg agagccgtcc gcgtcggctt
     1321 gcgggccgtg gcgcaccgga gcacacaatg gtcacaaggg gcacgaaaag cggccgaacg
     1381 caagactccg ggccgccggc actccacgac gggagcacag ctcgtgagcg tcgaaccgcc
     1441 gaactccggt cgccccaccg ggccgccgtc cggccccctg tccggccgcg cacagccacc
     1501 ctccggtccg ccgcccccgc ccccgccccc acctccgggc cggggcccgg cgccggacca
     1561 cgaaccccgc gaacccggcc ggccctggtg gaagtccgta ccgcgggtcg cgacgatcgc
     1621 cgtggtcgtg gccgcgctcg ccaccgtcgg cgtcctgctc acccgcggcg acagcggcac
     1681 cggcggcagc cgcgaggtct tcctccaggc cgcgaacagc cggggccccg accccttcac
     1741 cgactcgacg gcacagggga ccagcacctc gccggccacc ccgacgacgc cgccgaccac
     1801 cgcgctcacc ccgtcggaga ccgtgaccgc cggtgagaac agggtgcggg gctacaacgg
     1861 cggcacgccc ggcgtctacg gcggcacccg cgacgtggcc gcctgcgacg tcgagctgca
     1921 gatcacctac ctgcgggaga acccggaccg gaaccgggcg ttcgccgccg cgttgaagct
     1981 ggacccggac gacgtccccg cctatctccg cggcctcaca ccggtgctgc tgcgcatgga
     2041 cacccgcgtc accaaccacg gctaccgcga cggcgaggcc gacccgtacc aggcgatcct
     2101 ccagtccggc acggcggtcc tcgtcaacga ccgcgggctg ccgcgcgtgc gctgcgcctg
     2161 cggcaacccg ctgaccaacc cgctccagca gcacaccggc tacgagcgga tcggcgactc
     2221 ctggccgtcg ttcgaccccg cgaaggtcat cgtgatcctg cccgccgccg agcccgtgaa
     2281 gaccttcgtg ctccgcgaca tcgagaacgg cggctgggtc gcccgcgccc gcggcgacga
     2341 cggcgaccgg gacgtaccga ccaagccgcc gaaaatcccg cccacgccga cggacatctc
     2401 cccgcggccg ccgtcgccgg acaccggctc gcccacgggt gagaagccgt cgtccgagag
     2461 ctcgccgcgt ccggactcgt cgccgacccc gccaccgccc agcccgccca cgtcccccga
     2521 cacctccacg tccgaacctc cgcagtcccc tccggcctcc acctccgtgc cggacgtccc
     2581 ggactcgatc acccagtcga cgccgccgac gagcctgccg gtaccgggca cctccgtccc
     2641 ctcggtgtga cgcccactgc accggggact gtgccgcgcg actcggggta cgaggactgg
     2701 tgcagcagta tccggccagg ccggcgtggg agagagacag catgatcgag caccgggacg
     2761 gcacggtcgt accaacgagt atcgacgtgc ccgtggaacc gcttcggcgg acggcgcact
     2821 acaccggtga acccggatgc atcgcggagg cgcgggagtt cgccgcgcag ttcgtgaacc
     2881 agctcaggac cgagtggtgc gcggcgatcg gcgcgcgcgc cgaggaggcc ctgctgctgg
     2941 tggtcagcga actggtcacc aacgcggacc ggcacagcga ggggccctac atcctcgacc
     3001 tctcgggcac cgacgggtcc gtgacggtct ccgtctacga cagcagcgac gccctgcccc
     3061 ggcgcttccc ccgggacccg gaacgcatcg gcagacacgg cctggagatc gtccacgcgc
     3121 tggccgaccg cgtcgccgtc gagcgggtgc cggtcggcaa gcgggtgtgg gcggtcgtcg
     3181 cgctggcgga cgggtgaatc gcgctacacc tacgggtgag ccggccccgc gagcggggcc
     3241 gggtcccggc gtcaagcctt cacacgcggt ccagttcgcc gagcatgcct tcccgcagcc
     3301 gtacgatgat ccgcttcagc agccgcgaca catgcatctg cgagcagccg agctgttcac
     3361 cgatctcggc ctgggtggcc tcctccacga accgcatgtg caggatccgc cggtcgcgct
     3421 cgtccagctc ggccatgagc ggcgccagcg actggaagtc ctcgacgagc cgcagcccgt
     3481 gctcctcgac gccgatgaag tcggccagca ccgcctcgcc gtcctcgggg ccgtccccgg
     3541 tgagggcggc gtccagcgac gaggagttgt agccgttggc ggcgatctgg ccctcgatga
     3601 cctggtcctc ggagatgttc atcagcgtgg ccagctccgc caccgtcggc tcgcggtcca
     3661 gccggctggc cagttcctcg cgcgccttgg ccagctccac ccgcagttcc tggagccggc
     3721 gcgggacgtg caccgcccag gtggtgtccc ggaagaaccg cttgatctca cccacgatgt
     3781 acggcagcgc gaacgaggtg aactcgacct cgcgggacag gtcgaaccgg tcgatcgcct
     3841 tgatcaggcc gatcatcccg gtctggacga tgtcctccat gtcgtccccg cggccccgga
     3901 accggccggc cgcgaagcgc accagcgaga tgttcatctc gatgagcgtg ttgcgcgcgt
     3961 actggtactc gtgcgtgccc tcctccagct ccgccagccg gcggaagaac tggcgggaca
     4021 actcacgggc gtcccgagga gccacggacc gcgggtccac taccgccggc tccggctcgg
     4081 acgtcgtccc ggcgcgcgcg ctctcctcga cgagcggtgc gtcagacccg gtcacggcgg
     4141 tggcggtgtc cattgcctct cccacggaag tcatggtgcg acgaatgcct ctttcgggtg
     4201 tcgtgctggc gttgagttgt cctggcgtca cggagacgca tcggtgcggg tacccggcaa
     4261 gtggcggagc atgcactcca tgtgccggag cggcgagaaa cgatcggtgc gggcctcctc
     4321 ccggaggcac cttcccatgg cgccgcgtcc gccgcacgcg gacggcacgc ggcggttccc
     4381 ccgggcgttt cgtccgattc caccgagggc ggaacgccgg acccttcccg tcccggtccc
     4441 cgctcctagg ctgaggaggt gaccaaccaa gcgccgaacg aagcccgtgt catccctctc
     4501 cgcccccgca ccgcccgccc cgcgcggccg gcagccggca ccgcgtcacc cgcgcccgcc
     4561 cggcccgcgc cgccgcgcga gccggccgcc aaggagccgc tgtggcggga cctcgtcggt
     4621 gacgtcctgc ggcgggaacg cctcgcgcag gagcggacgc tgaaggacgt cgccgacgcg
     4681 gcccggatct ccatgccgta tctctcggag gtggaacggg gccgcaagga ggcctcctcg
     4741 gaggtcctgg cggccgccgc ccacgccctg ggactcggcc tcggcgacct gctgggactg
     4801 gcccagcggg agctggtccg ggtcacgtcc cggcactcca cgaccgggcg ccggcccgcg
     4861 ggctcgtcgt acgacgggct ctgcctggcc gcctgagacc ggtgcacggc cggcgtctca
     4921 gaccgtcacg aggcgccggc tcagcacctc gtcggccagc ccgtacgcca ccgcctcccg
     4981 cgcggtgaac accttgtccc ggtccatgtc cgcgcgcagt gtggcgatgt cgtggccggt
     5041 gtggcgggcc agcacctcct ccacctgtga ccggatccgg accatctcct tggcctggag
     5101 ggcgagatcg gagaccgtgc cctgccgccc gccgctggcg ggctgcccga gcagcacccg
     5161 cgcgtggtcc agcacgaacc gccgcccggc gtccccgccg gccagcagca cggccgccgt
     5221 ggacgccgcc tggccgacgc agaacgtgga gatcggcgcc cgtacgaagg tcatggtgtc
     5281 gtagatcgcc atcagcgagg tgtacgagcc gccgggcgag ttgatgtaca ccgagatctc
     5341 gttctccggt gccgccgact ccagatggag gagttgcgcg atgacgacgt tggcgacgcc
     5401 gtcgtcgatc tcggtgccga gaaagatgat ccgctccgac agcagccggc tgaacacgtc
     5461 gtacgaccgc tcgccctgcg gggtccgctc gaccacgtgc ggaatcgtgt aactccccat
     5521 gactacagcc ccgtccgtcg ccgcgtcgcc gccgggagga cgtccgtgaa ggactccacg
     5581 acccggtcga ccatgccgta ctcccgggcc tcctcggccg tgaaccagcg gtcgcggtcg
     5641 ccgtcccggg agatggtctc cgggctctgc ccggtgtgct cggcggtgat ccgctcgatg
     5701 gtccgcttgg tgaactccag gttgtccgcc tggatctcga tgtccgcggt ggtgccgccg
     5761 atgcccgcgg acggctggtg catcatgatc cgcgcgttcg gcagcgcgta ccgcttgccg
     5821 ggcgcgccga cgctcagcag gaactgcccc atgctggccg cgaaccccat cgtgagcgtg
     5881 gacacgtcgt tggggatgag ccgcatcgtg tcgtagatgg cgaggcccgc gtgcaccgag
     5941 ccgccggggc tgttgacgaa caggctgatg tcggtccgcg ggtcctccgc ggacaggatc
     6001 agcagctggc tgcacacccg gttcgcggac acctcgtcga cctgggtgcc cagcagcacg
     6061 atccgctgcc cgagcagctg cgcggcgagg tggtcgtcga accgcgtccg aggggtgtcg
     6121 ctctcctcgg cccgcggggt gagcacggtg agttgagtca tcggttctcc ttgtcgtcgt
     6181 acggaacgcc gtcgactcca cccttgcccc cggacgcggg ccgccggtga tttctctgcc
     6241 cgcggcagat tcgccgtggg cagagcggcg ctcagcccgt ctcgcgcagc tgccggaaga
     6301 acgcccgtac gtccgccacc agcaggtccg gctcctccat cgcggcgaag tgcccgcccc
     6361 ggtcgaactc cgtccagcgc acgatgttct cggtgcggtc ggccttgtgc cgcagcggga
     6421 gctggagttc ggccgggaag agggcgaccg cggtcggcgc cgtggacggc tcggcggggg
     6481 cggcggcgcg gccggtggcg tgcgcccgct cgtagtagac gcgggccgac gaaccggccg
     6541 tccccgtcag ccagtacagc atcacgttgg tcagcagccg gtcccggtcc acggcctcct
     6601 ccggcagctc ctcggagtcc gtccactccc ggaacttctc cgtgatccag gcgagttgac
     6661 cgacgggcga gtcggtcagc gcgtacgcca gggtctgcgg ccgggtcgcc tggagcacgg
     6721 cgtacccggt gccctcgcgc gaccacgcgt cccaccggcg ccaggaggtc agcgtgcgct
     6781 cccgctcctc ggggccgagc gccgccagct cctcctcggt cggctcggtg accgcctgcg
     6841 cgccgggcag caggttcaga tggacgccga cgacccggtc gggacgggcg cggcccagct
     6901 cgcgggagat cgccgcgccc cagtcgccgc cctgcgcgcc gaaccgctcg tagccgagcc
     6961 ggcgcatcag ctcggcccag gcgtcggcga cccgcccggc ctcccagccg ggttccgtcg
     7021 tcggcccgga cagcccgaag ccggggatgc tcggcagcac cacgtggaac gcgtcggccg
     7081 ggtccccgcc gtgcgccgcc ggatcggtca gcgggccgac cacgtcgagg aactcgacga
     7141 tcgagccggg ccagccgtgc gtgaggatca gcggggtcgc gtccggctcg ggggaacgga
     7201 tgtgcgcgaa atggacgttc gccccgtcga tcgtggtcgt gaactgcggc cactcgttga
     7261 gccgcgcctc ggcggcccgc cagtcgtact cgtgccgcca gtaccggacc agctcccgca
     7321 gatagtccgc cggcacgccg tacgcccagc ccaccccggg cagctggtcc ggccagcggg
     7381 tgcggtcgag gcggtcgtgg aggtcggcga ggtcgccgtc cgggacggcg agacggaagg
     7441 ggcgcggggc atcggcaggc gaggacgtga tcatgcccgg gatgctagac gcgtgcggtg
     7501 gcacggccgt acggatttcg tcccggccgg accgatgagt ttcccggcgg acgccggtcg
     7561 acactcctga ccgcgttccc tacccaggag gtgcccatga ccaccgacgg attcaccacg
     7621 tgtctctggt tcgacggcca ggccgaggaa gccgcccatt tctacgtctc ggtcttcaag
     7681 aactccggcg tcggcgaggt cacccggtac ccggagggcg gcttccgccc cgccgggacc
     7741 gtgctgaccg tcgagttcac cgccaacggc cagaagttcg tcgcgctcaa cggcggaccc
     7801 gagttcaagt tcaacgaggc gatctccttc cagatcctct gcgccgacca ggaggaggtc
     7861 gaccactact ggaccaagct gaccgaggac ggcggcgagc ccggcccgtg cggctggctc
     7921 aaggacaggt acggcgtgtc ctggcaggtc gtcccggagc ggctcaccgc gatgatcggc
     7981 gacccggacc ccgagaaggc ggcccgcgtc accaagacga tgatggcgat gggcaagctc
     8041 gacatcgccg ccctggaccg ggcgtacgcg ggcgagtgac gcctcagccg ccgccccggg
     8101 ccgccgcgcc gaccaccctg gtgatctccc gggcgatgcg cagcacaccc ggggagcgga
     8161 ccgggcacgg cttcggggtg gacgtcgtcg gggcgagaca gaagtgcagg tggtcgtcgt
     8221 cccggtgcag ggcggtccgg tcgcggcccg gctcggtgca gtagccggag tgcgcccgct
     8281 cccaggcggt gcacggcagg aaccgggccc aggtgtagcg gccggaggcg gggctcaccg
     8341 cccggcccgc gtcggccacc ggctcgcccg aggcggccgc cagctcctcg tagacggcgt
     8401 tcaccttccg cacccgctcc ggggtgatcg gatccgggcc ctggagcacc cacacgatcg
     8461 ccggcggcga ctggcccccg gcgcccgtga tctgccccgc cagccgccgg gcgtcggcgg
     8521 tgtaccgctc cagatagcgc tgcggggcgg cgccgtaggt gatcccgtcc atgcacggcg
     8581 tgtaacccca ggcgttcccc cagaactgca gcaccacgac gtccggccgc accgaccgga
     8641 ccagcgccgc cgccttgtcg gcgtccggca ccagggaccg ctcgccggtg ccctccaggt
     8701 agtcgcacag ggtggtgccc gagtacgggg cgctggtgta gtcggcccgc aggtcccggc
     8761 gcagctcccg gccgaggacc cgctggttct ccatcgccag ggagtcgccg agatacagca
     8821 cgaccggtgg ccgcgcgggg gcggcgggcg cctgctgccg ggtgggggcc gacgcctcgg
     8881 gggtgacgga cgtcccgggc gcgaccggtg ccgccggcgg tcgcggcggg tccccggtcg
     8941 ggtccccggt cgggtcgccg cacccgccga gcagcatcgc accggccagc gtccaccccg
     9001 ccacccaccg tccgcgcatc aggccgctcc cgccccgcca ccgacagagc tcaccaggca
     9061 agcacagccc ggcggcgggg ggaagacccg cgtcagacgc ggtcggccgc gatcagcagg
     9121 tactggaaac tgccgttgcg gtaggcggtc aggaaggtgt cctcgatgcc ggtgaccaga
     9181 tggtcggcct ccttgcgcag ctcccagtac gggatggcgg cctcggtgag gtcctcgacg
     9241 tgcacgggga cgagccggtt gcgggcgagg gcgcggaagt acgccgagcg cggatggatg
     9301 tcgcagatgt agtgcgcgtt gatcagcgac acctcccgcg aggcctggcc gtaggtgtcg
     9361 ttgtagcagc cggtgatcac cacgtagcgg ccgccgcggc gcagcagccg ggcgtgctcg
     9421 gcgaacagca ggtccagctc gacgtacatc gtggactcgt tgttccacga ggccgcgaac
     9481 gcgcccgacg ggaagccggt gtcgagcatg ttgcggtggt ggtagcgcac cttgtcgtcg
     9541 atgccccgct tgcgggcctg cgcgccggcg aactcggcct gcttggctga gatggtgacg
     9601 ccgtcggcgt ggcagccgta ccgcagatgc gcgaccacgc tgccaccgcc gcgcccgcag
     9661 ccggcgtcga agacccggtc ggtgggggag agggggccga gatgggcggc gaggagttcg
     9721 gcctgggcgt gctccagccg gtgcagttcg gccgtcaccc gggcacggcg ccggtccggg
     9781 tcgggctcgt cgagcaccga gcggtcggcc tggccgacgc cgtagtgatg gtggtagagg
     9841 tcgtcgatct tgccgagttc caggttgacc gggttctcct cggcgttcca gtactccgcg
     9901 acgcggttct ggtacgtgga ctgggtcggc accgccgtcg tggtgcgggt gtggggcgcg
     9961 atggtcaacg gtgactcctc agggcgcggt cgtgcgggtg ttaccagtag tcgggcaggt
    10021 ggtagcggtg ggtgttggtg gcgtgccact cgtggttgcc ggacacccag gccgcgagcc
    10081 cggccagata gcgggccagc agcgggttgc cggcggagag cgcggcggac tcctcctcga
    10141 aggcgtccat gatccggttg tggatctcga ccgcctccag ataggcggcc ttcagcccgc
    10201 accgctcgtt gcgggcgatg acctgcggca ggttcagatg gtccgggtcg ttggccagct
    10261 ccttggtgaa ggagtacagg tcgttgacga gggtggtggc gttgcaggcg agcgcggtca
    10321 cccgctggac ctcggggcgg gcgtacagcg cctcgggcag ttcgtagccg tccacggcgt
    10381 ccacgatcga cagacaggga cggaagttgt tgaactgccg catcaccagg tactcccaca
    10441 ctcgcggcac ataccgggtc tccgcccagg cggcctcccc gagatagccg aggtgcagcc
    10501 gggcgacgtc gtgcacgaac cgggacacct ggctgggcgt ggcgaacgcg gcgtagtcct
    10561 tcagggccca gtggtacgag cggagcgaac cgtcggcctc catgccgtgc cgccaccgcg
    10621 cctccagctc cggggtgccg tgatacgggt cgagcgccga ctgggccagc accagccgcc
    10681 cgccgaggcc gcgcggggag ccgccccggt cctcgcagta gcagtcgtcc acgatgttct
    10741 cggcgagcag cagcttcccg gccgcggtga ggcggtccag gtcgagcgcc ccgggatgct
    10801 ggagcgccac cgcccgcccg aactggaacc cggtgaagtc ccccgtccac tccggcggga
    10861 acagctccag ctcccgggcc caggcctcca gcctgcggtc cacctccgcc gccttctcgg
    10921 ggtcggcggg cacggcgggc cggtggcgca gtcccgggat cgccccggtc cgccgggccc
    10981 gcagggtcgc ggccaggctg ggcgggccgg gcggccggaa cggggagggg ccggtcacgg
    11041 gcggcgatcc gctcattccg gcatccgccc gatctgcacg ttctccagga tgcccgcggc
    11101 gtcgggcacc aggatggcga gcgagtagta ggcggtcacc aggtagctca tgatcgcggt
    11161 gctgtcgatg cccatgaacc gcacgttcag accgggctgg tactcctccg ggatgcccgt
    11221 ctggtacagc ccgatcacgc cctggtcggc ctcgccggtg cgcagcgcga tgatgctgct
    11281 ggtgtgccgc tcactgaccg ggatcttgcc gcacgggaag atcggcacac cccgccaggc
    11341 gggcacctcg tgcccgtcga cgttcaccgt gccgggcacc agaccgcgcc ggttgcactg
    11401 ccggaagaac gcagcgatcg ccttggggtg ggcgaggaac aggcgggtct tgcggcgcat
    11461 cgacagcagc tcgtccatgt cgtccggggt cggcggcccg gagaaggtgc tgatccgctg
    11521 cccgtagtcg gcgctgtgca gcagtccgaa ctcccggttg ttgaccagtt cccactcctg
    11581 gcgttcgcgg atctcctcga tggtgagccg cagctgctgc tcggtctggt tcatcgggtc
    11641 gttgtagagg tcggcgaccc gggtgtgcac ccgcagcacg gtctgggtga gcgacaactc
    11701 gtactcgcgc ggggtgagtt cgtagtcgac gaagccgccc ggcagcacgg gttcgccgac
    11761 gtggccggcc tgcaccggga cgtcggcctc gcccttgcgg ttcatcggcc tgctctgccg
    11821 ctcggcgtag gccgacagat gcgcggcgag ggagggggcg cggtccgcga actcctccag
    11881 ggtgtcccag ggcagcgcga gcacggtgcc cgcggtgtcg gcgcgcaccg agctgagcca
    11941 gagcgggtcg tcccggccga cggcctcgtc gcccagcccc tcgccgtcgg tgacgacgtc
    12001 gatgacctcc tccccgccgt acttgccggt cgtgtagcgg gtgaaccggc cgtgcgcgac
    12061 gagataggcc tcggtgaccg gctgcccggc ctcgaacagg acctcgccgg cccggacctc
    12121 gcgcacctgg aagcgggtgg cgatccccct gaggacctcg gtgtcggagt agccgcgcag
    12181 gaccggcagt tcggtcagcg tctccgggat gacccggacg tcgtcggcgc cgttctgctc
    12241 gaactgcacc cgcccccggc cgaggcgcag ctgcagacgc cggttgaccc ggtaggcgcc
    12301 gcccttgacg tccacccacg gcagcgtctt cagcagccac cgcgaggtga tggcctgcat
    12361 ctgcggttcg gacttggtgg tcgtcgtgag ctggcgggcg gccagggtgc tgaggctggt
    12421 gggttcgggg acgggctcgt cggtggcggg accggtggcg ctgtcgggcg tggacacatt
    12481 ccctcctggg atgcacaggc gtgagcggaa cggccggagg tggcacgcgg tcgtgcgcgg
    12541 gatcaagcca aacagcggcc gccggtgacg ggtacggcgt gaaggggtcg gcttgcgcac
    12601 cccggaggcg caaacccccg gttgaggcgg cctgcttctc gggaggtgtg gcgcgaggcg
    12661 tgtgtacggc tcgtgccctg ggcgcacacg gcgcacggca gccccctggg gctcacgggt
    12721 gtgtccggcg cgcggggccg ccccctgatg gctagcgtga aagaccggac catccaccga
    12781 gaaccggaag agggccgcga tcatggccgt gaaacctgag ggccacccct gctgggccga
    12841 cgcgatgttc accgacctcg aaggggccaa gagcttctac ggcgaggtcc tcggctggac
    12901 cttcggcgag tcgtcgtcgg agcacggcaa ctatacggag gcctaccgcg acggcaaggc
    12961 ggtcgccgcg atcgtcccgc cgacgccggg gcaggagggg caggacgagc agtcgcagtg
    13021 gtgtctgtat ctcgcctctc ccgacgccgc cgcgaccgcc gccaagatcc gcgacaacgg
    13081 cggcgagctg ctgatggagc cgatgaccgt gggcgactac ggcaccatgt gcctggcccg
    13141 tgacccctca ggcgtggtct tcggcgtgtg gcaggccggc agccacgagg gcttccaggc
    13201 gcccatggac cagccgggcg cgttctgctg ggcggaggtc ttcacccgcg agccggagaa
    13261 gtccgacgcg ttcttcccgg cggtgttccc gtacacggcc cggcagatgg aggacgacgg
    13321 cgtcgacttc cggatcttca acgtgggcga cgccccggtg ctgggccgga tgcggatgac
    13381 cgacgacttc ccgcccgagg tgccgccgta catcaacgtc tacttcagcg tcgccgactg
    13441 cgacgaggcc gtcgccaagg ccaccaagct cggcgccgtc ctccggttcg ggccgatgag
    13501 cagccccttc gggcggttcg ccgcgctcac cgacccgcag ggcgcgaact tctcggtgat
    13561 cgacacccag accaccgagg gcgacatgcc ggagctcacc gacgtctcct gaggactccc
    13621 gggaccggcg tcccggcccg tccatggcat catcgggcac atgcgtgaac gagtggtggc
    13681 cgcgtgcgac ggggcttcga agggaaaccc cggaccggcc ggctgggcct gggtcgtcgc
    13741 cgacgagacg gagacgccgg accgatggga ggcgggcccg ctgggccggg ccaccaacaa
    13801 cgtcgcggag ctgaccgccc tggagcggct gctggcggcc accgacccgg ccgtgccgct
    13861 ggagatccgg atggactcgc agtacgcgat gaaggccgtc accacctggc tgcccggctg
    13921 gaagcgcaac ggctggaaga cctccgccgg gaagccggtc gccaaccagg acctggtcgt
    13981 ccggatcgac gaactgctgg acggccgctc ggtcgagttc cgctacgtcc ccgcccacca
    14041 ggtcgacggc gacccgctca acgacttcgc cgaccgcgcc gccagccagg ccgcctccgt
    14101 ccagcagccg gccggcagcg gcctgggctc cccggagccg ccgtcggccc cggacgcccc
    14161 gcccgccaag gcgccgggcc gccgctcccc ggcggcccgg aagaagagcg gcggctcctc
    14221 gcgcacgatc aaggcgaagt tccccggccg ctgcctgtgc ggccgttcct acgcggccgg
    14281 tgagcccatc gcgaagaacg cgcagggctg gggccacccg gagtgccgca ccgcggccgc
    14341 cgggtgaggc gcggcacgct cacaccacgc cgcgccagcc gccgctctcc tggccgcgct
    14401 cctcgatgaa ccgcttgaag cgctccaggt cgcccttggt ctgccgcttc acgaagccca
    14461 gcttgtcacc gacggtctcg gcgacgccgt ccggatggaa ctccatctgc agcatcacct
    14521 tggtgtggtc gtcgtcgagg cggtggaagg tcaccacgcc ggcctgccgg gcgtccccgg
    14581 cgacggtcgt ccaggcgacc cgctcgtccg ggagctgctc ggtgatctcc gcgtcgaact
    14641 cccgccggac cccgtcgacc ttggtcaccc agtgggtgag cgtgtcggtg cgctgctcga
    14701 tgcgctccac cccgctcatg aactcgggga aggtctcgaa ctgggtccac tggttgtagg
    14761 cggtgtgcac ggggacggcg acctcgatgg attcctcgac ctgcgacatg cgcgcatcac
    14821 tccttcgtcg ttcgtcggac aggtccggcg cgagtacccg tgacctcggc ggcgatgccc
    14881 tcagtcggtg tcgaaggtgt agtgggcggt gtggtcgagc aggtcggcgg gggcggtgtc
    14941 gttccacggc ttcatcttct cgccgaggtc gaccacgttc ggcgtgcccg cggcgggcag
    15001 gtagccggag tccgggtggc gtcgctgcca ctcggcccac agcttgtcga cgtaggcgtg
    15061 gtgcagccag aacaccgggt cgttggggga catcccggtg gccatctgcc cgccgaccca
    15121 gacgtgcacc cggttgtgca ggttgacgcc gcgccaccct tccaggtggt tgcggaagcc
    15181 gtccgagccg ctgttccagg gcgccatgtc gtacgtcggg atggccagca ccgactccac
    15241 ctcggcccgg gtcggcagtt cccgcaccga ggtggcgagc gaacgccgca ggtaggtccg
    15301 tccgtcgacg cggacgttga tcgaccagtt gccggcggac gcggcgaacg gcccgtccat
    15361 cacccggccg tccgtgctgc gcccggtgcc gccgaggaag tccggcgccc acagcgaggc
    15421 ccgcacggtg cggtcggtgg accagtccca gtacggcagc gccacggagg cgtccacgga
    15481 ctgcagggcc cgttcgaact ccagcaggta tctgcggtgc cagggcagga aggacggcga
    15541 acggtggccg gtgcgctcgc cgttgtcggt gtcggagact atgaactggt tgtgcgtggt
    15601 gacgaagtcg tcgtagcggc cgctgcgctt gagctccagg acggcggcga cgaagcgccg
    15661 cttctcgtcg gcggtcagcg tcgcctggtt cttccggacg gtcatcttgc gtgctccaaa
    15721 gggcttgcgg ggtggttcag ttggcgggga acggcagcag gcgggcgccc tggagctcgt
    15781 cgaccgcggc gcgtgcggcg gcccgcgggg tgggcaccgg gtcgtagtgg ctgacgacgc
    15841 tgatccagct gccgtcggcg ttgcgcatca cgtgcagttc caccccgtcg atgaacacgg
    15901 cgtagccgcc gccgtggtgc tgatggcccc cgccggccgg cctgccctgt atccggcggc
    15961 ccttgtagac ctcgtcgaag gactgcgggg cgccgtggtc gccgtggtcg gcggcgatcg
    16021 cctggggtgc ggcgccgagc gccgtggcgc cgccggcggc ggcggtgagg gcggccgcgg
    16081 cggtgagcgc gcggcgacgg ctgagttccg gcatacggac ctccggggtg cgtgtggttg
    16141 acgaccccgt atgcctatcg gcccggtcac aagcgggaga aatccgccga gaggggttgg
    16201 ctccgatccg gacaattgcc tacatgtcgt gcagtattga acaaagatga tcttgccgtg
    16261 agagtgcccc gcgtgacccc ggaacgggta attccttgcc gtggccgccg ggtgatccgt
    16321 gatctttcgc gcgggcgcgc gccacccgtg gcctggctca cgccgggaaa gtggcgtgaa
    16381 acggcgtagc cgccggacgg caaggtcgcc cgcgcgccgg cctcgcgcgg ctgagccctc
    16441 agggcagcag ccggtcgagg aaggcgttgc cgaacacgtg gtgcgggtcg agccggtcga
    16501 ggatcccggc cgcccgcgtc cacgccccgt ccccgaacga ggcgggcacg gcccgctcca
    16561 cgacctccgg atcgctccac gcggcccgcc cggtgtagcc ccagcccttg gaccactcca
    16621 cccgggccag cccggtgccg ccgccgtcgt acgtgcccag cacgtaccgc tccagctccc
    16681 gcaggaactc ctccgcggac ggggttcccg gcagggtcag cacgttcagc cacaccgccg
    16741 tgtcccactc gggccgcccc gccaccggcc gcagcgccga cagcagcggg gcgcgggcgc
    16801 cgtccacgcc ggcgtcggcc ggatcgtcca gaccggtcac ccggatctcc accgagccgt
    16861 tgaccgggaa gcggccgcgg gcggcgtacg ccgtcagcag cccgcggtag tacgccgtga
    16921 acccggcgac gacctcctgc acccgggccc gctcggtgac gaccgcgtag ccgtcggtgt
    16981 gcacccgcag ggtggtgggc cgcagataca gcagcgtgtt cttcgacggc ccccagatgt
    17041 ccgccgaccc ggtcgccgcc agccccagca cggccgcctc gtactgggct acgccgagcg
    17101 ccggcgccag ataccaggcc gcccccgcga ccagccgccc cactagatcg gccaccggcg
    17161 tcggaaggct gtcggagaac gggtagttgt acggcccggt aacctcccgc gacccggccg
    17221 ggcgggtcgg cgccacgctc cacaccttca gccacggatg ctcggtgaag gcgaaccaga
    17281 tcgcctccgc ccgccccgac cggtccagga agctcgccag cgtccgcccg ccccggccgg
    17341 gcgccgcgaa cagctccccg gccgggatgt ccgtccggct gacacagcgc agccgggtgt
    17401 cggcgccgac ccgcagcacc acctcggtga cgaagccgcg gcccaggtgg gcgaggagcg
    17461 ccgcgcagtc cgcctcgtcc cgccggaacg tacgcagccg gtacgccccg ccggcctcgt
    17521 cccacacgac cgccgtcagc gacagcacga ggttgctgag cgagccgaag gtgtgcccgt
    17581 cacggcgcgc ctcgccgtcg gccggtacgg cggtgccgtg cgcgtcgatc gcgagggctc
    17641 cgccgagggt cagcaccccg ggcgccgggg ccgcggtgag gccgagcccg tgctcctcca
    17701 ggaacgtgag cagcgcctcc agcgtgacgc ccgtcccggc gcggaccgag gaaggagact
    17761 ccagggccag gccggtgagg tgcggagcgg tgtcgacgag caggacgggg gcgtcgggag
    17821 gcgtcccctc cgggatcgtc agcggcgacc agccgtgcga ggcaccccgg gcgcggaccc
    17881 gccggcccgc gcgccaggcc cagttgacga cctcggccac ctgctccgcc cgggccgggg
    17941 cgcacgccca cagccccgtg gcggtgatct cgcccgtcca gttgcggtat ccggtgcggt
    18001 acaggggcac ttccgccggg aaacccggca actcctcggc ggcggccgcc ggatcggcga
    18061 cggccagggc gggggcggcg gccagtgcgg ccgtggtgcg caggaagccg cgccggctcc
    18121 agggatcggt cacgcgctca cgctaggggc cgctcgcccg gcgcccggtg accgctcgcc
    18181 acgcatcaca cgtgtgggtg acagaaccgc ggaaccggga ccggaggcgt cggctccggg
    18241 cagggacggg cgggtgacag actgacgcca tggaagagcg tgtattcgac agatggggtc
    18301 agcgggcgtc cgtcatcggc ctggggacct ggcagctcgg cgccgactgg ggcgacgtcg
    18361 acgacaagga agccctcacg gtgctggagg ctgcggccga gtcgggggtg accttcttcg
    18421 acaccgccga cgtgtacggc gacggccgca gcgaacagac catcgccgcg ttcctgagcg
    18481 gccgtcccga tctgcacgtc ctcgtcgcga ccaagatggg ccgccgcgtc gaccagatcc
    18541 ccgagaacta cgtactcgac aacttccgcg cctggaacga ccggtcccgg cgcaacctcg
    18601 gcgtcgaccg gatcgacctg gtgcagctgc actgcccgcc gacccccgtc tactcctcgg
    18661 acgaggtgtt cgacgccctg gacaccctcg tggcggagga gcgcgtcgcg gcctacggcg
    18721 tcagcgtgga gacctgcgag gaggcactga ccgcgatcgc ccggcccggc gtggccagtg
    18781 tgcagatcat cctcaacccg ttccgcatga aaccgctgcg ccaggtcctc ccggccgcgc
    18841 gcgaggccgg cgtgggcgtc atcgcccggg tgccgctcgc ctccggcctg ctgtccggca
    18901 agtacaccaa ggacacggtc ttccccgaga acgaccaccg cacctacaac cggcacggcg
    18961 agtccttcga ccagggggag accttctccg gcgtcgactt cgccaccggc gtcgaggccg
    19021 ccgccgagtt cgccgcgctc gcccccgagg gatacacccc cgcccagctc gccctgcgct
    19081 ggatcgccca gcagcccggc gtgaccacgg tgatccccgg cgcccgctcg ccggagcagg
    19141 cccgcgccaa cacggccgcc gcacacctgc cgccgctccc cgacgccacc ctcgacgcga
    19201 tccgggacct gtacgaccgg cggatcaagg accaggtcga gggccgctgg taggacgccg
    19261 gcagccgtcg ccgcaccgaa acccctcggc ggggacactt ctgccgccga gggggaaccc
    19321 ggaggggaag gacagtggat cgttcccaag gggaggcgga gtcgtgacgg ccggcgaaga
    19381 cagcgcgaag agggccagag ggcgcaacga gacggaggag gagagagccg accggatgtg
    19441 ggtcgagctc atccaggaag tgcgcgtggc ccagatgggc gtccagatcc tgttcggttt
    19501 cctgctcacc gtcgtcttca ccccggtgta ccgcgaactg cccgacaccg accgcaccat
    19561 ctacatcgtc acggtcgtcc tcggggccgc cgcgaccggc gccctgatcg gaccggtctc
    19621 cctgcaccgg ctggtctccg gccggcggat caagccgcag gcggtcagct gggcctcccg
    19681 gatgaccatc gtcggcctga tcctgctgct ggccaccacg accgcctcgc tgctgctgat
    19741 actgcgggtg gcgacccacg acgacttcgt cccgtggctg gtcaccggtg tcctgctgtg
    19801 gtacctgctg tgctggttcg ggatacccct gtggacccgg caccggtaca ccagccgcgg
    19861 ggagccgccg ctcagccctc ggcgatgacc tcggccagga agtcgtccac ccggatccgc
    19921 tcccggccgg gcgccaccac ggcgtgactg tcacgcagga aggccgcgac cgccggggcc
    19981 caggcgaaca ccgtcgcgtg atggtgcccg ccgtcggccc gggggtcgcc gaagaagtcc
    20041 agccgcagct cctcccagcg gtccgtcgac gccggacgca tccggacgtc acccaccccg
    20101 accggccggc acagcccgtc ggccagcatc tcgcggtcca gccgccaccg ggcgagcacc
    20161 cggccgtcgt ggctgaacac catggtcacg gcgaacgggt cctcggcgtc gtacctcagg
    20221 tgggcgagaa ccgggaaacg gtccgaggtg ccggcctgga gctgcatgac cagggtcctg
    20281 tgcacgaagc tgttcaccag aaggcctccg gggagaacgg acgtaaagcc ttccagtacc
    20341 cccgttccgc acaagatgct cagctctccg ggtgattctc ccgcgccccg cgcagcgccg
    20401 tgaggcagcc gccgatggcc cgctgcagtt cctccagccg ctggaccatg tcgtcctcgt
    20461 agaagtcccg ggcgtcgtcg aaggtcagtt cctcgaacgc cttcgtggcc ttctgcagac
    20521 tgctgtagaa cttcgtccgc cgctcccgca cgcgcagctc ggggtcggcc tccacggtct
    20581 cgacgacgag ggaccgcagg gtgtcgtagg cctcggtggc ccactcgccg gcgtcctcgt
    20641 cctcctccag ctcgtcgatc agcgacagat gccgctcggc ctcccggcgc agctcggcgg
    20701 gcgcgtcgac ggtctgcccg gccggggtgc ggatcactcc ggactcggcg atctgccgga
    20761 cgtagccgat gcggtcggcc gaccggctct cggtggccac ggccttcttc aggtcgtcgg
    20821 tgcggaccac gtcccgggcc agctccgcct ggagctcggg gtcctcccgc acccggtcga
    20881 gcagggcccg gcgggccgcc cgggcggtgg acgggtcggc gaggatcgcg gcgcgcagcg
    20941 cggtggggtt ctcggcgacc tcgagcgcct tggtcgggcg gatgccctcg gcctcggcgg
    21001 cctcggcgat ggcggtgccg cgctcggagg cggcgctgga acgggcgacg tagtagctca
    21061 gccacacgtc ggcgtccggc agctcgacct cctggcccgg cgtgagcgcc tcga
//
