LOCUS       NZ_LIVZ01000007        10405 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0107 scaffold7, whole genome shotgun sequence.
ACCESSION   NZ_LIVZ01000007
VERSION     NZ_LIVZ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0107
  ORGANISM  Streptomyces sp. TSRI0107
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 730707)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 730707)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905845.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,745
            CDSs (total)                      :: 7,667
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 200
            CDSs (without protein)            :: 200
            Pseudo Genes (ambiguous residues) :: 0 of 200
            Pseudo Genes (frameshifted)       :: 85 of 200
            Pseudo Genes (incomplete)         :: 158 of 200
            Pseudo Genes (internal stop)      :: 13 of 200
            Pseudo Genes (multiple problems)  :: 51 of 200
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:19:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 566666
            Orig. end                         :: 577071
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVZ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10405
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10405
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10405
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5405](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5405
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    complement(222..236)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     misc_feature    408..422
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.43"
                     /tool="antismash"
     gene            complement(591..1436)
                     /locus_tag="AMK31_RS21870"
                     /old_locus_tag="AMK31_21570"
     CDS             complement(591..1436)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009338057.1"
                     /locus_tag="AMK31_RS21870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21570"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_073942272.1"
                     /transl_table=11
                     /translation="MNTVLGRRARALAATTATAGLVLLAGCTSSDNGEGGTKTAAGGVE
                     LVKAGQLTTCTHLPYPPFQSEIDGKVQGFDVALIDLVADDLGVKQDIVDTPFENFKTGA
                     FLNSGECDLAAAGMTITEERKKNVDFSDPYFDATQAVLADKDSGISSVADLKGEKVGAQ
                     AQTTGEDYAKSQGLDPVSFESSDAVLNGLRTGQVDAVVIDYPVVQGWLKDKANADAFEV
                     AEQINTGEQYGFTVKKGNDKLREAINKAIADAKADGTYKKLYEQWIGPYDESAASPSAS
                     "
     misc_feature    complement(1469..1483)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.31"
                     /tool="antismash"
     misc_feature    1634..1649
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.37"
                     /tool="antismash"
     gene            1660..2760
                     /locus_tag="AMK31_RS21875"
                     /old_locus_tag="AMK31_21575"
     CDS             1660..2760
                     /NRPS_PKS="Domain: Aminotran_5 (17-295). E-value: 2.2e-29.
                     Score: 94.5. Matches aSDomain:
                     nrpspksdomains_AMK31_RS21875_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019329315.1"
                     /locus_tag="AMK31_RS21875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21575"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_073942436.1"
                     /sec_met_domain="Aminotran_5 (E-value: 3.2e-23, bitscore:
                     77.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPFLDLPPLTAARFAAIEDRVARLLGTRQDVVIMQGEALLPLE
                     GAIRATAGPGTTALNVITGPYGQTFGDWLRDCGATVHDLSVPFHTAVSAEQIRKAFAEH
                     PGIDFVSLVHAEAATGNTNPVAEIGEVVREHGALFYLDAVASVGAEPVLPDAWGVDLCV
                     IGAQKAMGGPAGVSAVSVSERAWARMAANPQAPRRSYLSLLDWKERWVDGGRKALLHAP
                     AQLEMLALEACVERIEAEGLETVMARHRSAASATRAGALALGGGLEPYVHDAAEAAPVA
                     TTLRAPSGVAASDLVARALATDPALPLAAGGGALAREMIRVNHYGPDAAPGTIQAALAA
                     LGAALAEQGLPVDPDAARRAAEQAWH"
     aSDomain        1711..2544
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS21875_Aminotran_5.1"
                     /evalue="2.20E-29"
                     /label="AMK31_RS21875_Aminotran_5.1"
                     /locus_tag="AMK31_RS21875"
                     /protein_end="295"
                     /protein_start="17"
                     /score="94.5"
                     /tool="antismash"
                     /translation="AIEDRVARLLGTRQDVVIMQGEALLPLEGAIRATAGPGTTALNVI
                     TGPYGQTFGDWLRDCGATVHDLSVPFHTAVSAEQIRKAFAEHPGIDFVSLVHAEAATGN
                     TNPVAEIGEVVREHGALFYLDAVASVGAEPVLPDAWGVDLCVIGAQKAMGGPAGVSAVS
                     VSERAWARMAANPQAPRRSYLSLLDWKERWVDGGRKALLHAPAQLEMLALEACVERIEA
                     EGLETVMARHRSAASATRAGALALGGGLEPYVHDAAEAAPVATTLRAPSGVAASDL"
     misc_feature    2838..2852
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.76"
                     /tool="antismash"
     misc_feature    2847..2861
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    2852..2865
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.33"
                     /tool="antismash"
     misc_feature    complement(2966..2981)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    complement(2976..2991)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     misc_feature    3110..3122
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            3147..3665
                     /gene="ectA"
                     /locus_tag="AMK31_RS21880"
                     /old_locus_tag="AMK31_21580"
     CDS             3147..3665
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018545812.1"
                     /locus_tag="AMK31_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21580"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_073942273.1"
                     /transl_table=11
                     /translation="MTAAQADLHIDRPSVADGAAFWRLAKESGTLDLNSSYSYLLWCRD
                     FAATSAVARDGDGEPIGFVTGYLRPDRPRTLLVWQVAVDAAHRGRGIAARLLDGLAARV
                     AAEREVICVETTITPGNTASQRLFTSFAERHGARVEREVVFDTPLFPDGPHDPEVLYRI
                     GPLTPHLSH"
     gene            3679..4950
                     /gene="ectB"
                     /locus_tag="AMK31_RS21885"
                     /old_locus_tag="AMK31_21585"
     CDS             3679..4950
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-366). E-value: 2e-72.
                     Score: 236.0. Matches aSDomain:
                     nrpspksdomains_AMK31_RS21885_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007448159.1"
                     /locus_tag="AMK31_RS21885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21585"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_073942274.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1e-77, bitscore:
                     256.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITQPDLSVFETLESEVRSYCRGWPTVFDRAHGSRMYDEDGHEY
                     LDFFAGAGSLNYGHNNPVLKRALLDYLERDGVTHGLDMSTTAKRSFLQTFQDLVLRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGREAIVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFDGRVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARP
                     EWLRALAELCERQDMLLIVDDIQMGCGRTGAFFSFEEAGITPDIVTVSKSISGYGLPMS
                     LCLFKPELDVWEPGEHNGTFRGNNPAFVTATAALEMYWTDGSAMEKQTRSRGEQVEQAL
                     IAVTEENLADVKEYRGRGLVWGLEFHDKDRAGRVARRAFELGLLIETSGPESEVVKLLP
                     ALTITPDELDEGLTTLARAVRETA"
     aSDomain        3763..4776
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS21885_Aminotran_3.1"
                     /evalue="2.00E-72"
                     /label="AMK31_RS21885_Aminotran_3.1"
                     /locus_tag="AMK31_RS21885"
                     /protein_end="366"
                     /protein_start="28"
                     /score="236.0"
                     /tool="antismash"
                     /translation="FDRAHGSRMYDEDGHEYLDFFAGAGSLNYGHNNPVLKRALLDYLE
                     RDGVTHGLDMSTTAKRSFLQTFQDLVLRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     REAIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGRVPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARPEWLRALAELCERQDMLLIVDDIQMGCGR
                     TGAFFSFEEAGITPDIVTVSKSISGYGLPMSLCLFKPELDVWEPGEHNGTFRGNNPAFV
                     TATAALEMYWTDGSAMEKQTRSRGEQVEQALIAVTEENLADVKEYRGRGLVWGLEFH"
     gene            5001..5405
                     /locus_tag="AMK31_RS21890"
                     /old_locus_tag="AMK31_21590"
     CDS             5001..5405
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337952.1"
                     /locus_tag="AMK31_RS21890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21590"
                     /product="ectoine synthase"
                     /protein_id="WP_073942275.1"
                     /sec_met_domain="ectoine_synt (E-value: 2.4e-55, bitscore:
                     181.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFKDIEGTDRHVKAASGTWESKRIVLAKERVGFSLHETILY
                     AGTETSMWYANHIEAVVCVEGEAELTDHETGRTYTITPGTMYLLDGHERHTLKVKEDFR
                     CVCVFNPPVTGREDHDENGVYPLLTEPEEV"
     gene            5413..6327
                     /gene="thpD"
                     /locus_tag="AMK31_RS21895"
                     /old_locus_tag="AMK31_21595"
     CDS             5413..6327
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477733.1"
                     /locus_tag="AMK31_RS21895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21595"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_073942276.1"
                     /sec_met_domain="PhyH (E-value: 1.8e-40, bitscore: 134.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTTTTTTTATVTDLYPTRGASEVLVPRQDPVVWAAPDAPGPIG
                     PDGLQAFERDGFLAIDQLITEDEVAVYRQELERLVSDPAIRADERSIVEPKSQEIRSVF
                     EVHRISEVFANLVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHA
                     EDGLPNMRTVSVSIALTENYDTNGGLMIMPGSHKTFLGCAGATPKDNYKKSLQMQDAGT
                     PSDEALTKLASEYGIRLFTGKAGSATWFDCNAMHGSGDNITPFPRSNVFIVFNSVENTA
                     VEPFAAPVRRPEFIGARDFTPVR"
     gene            complement(6474..7535)
                     /locus_tag="AMK31_RS21900"
                     /old_locus_tag="AMK31_21600"
     CDS             complement(6474..7535)
                     /NRPS_PKS="Domain: Aminotran_5 (57-347). E-value: 1.1e-25.
                     Score: 82.3. Matches aSDomain:
                     nrpspksdomains_AMK31_RS21900_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671936.1"
                     /locus_tag="AMK31_RS21900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21600"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_073942437.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-21, bitscore:
                     71.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPTETFDSLVRAEFTPKSTFLNTASNGLLPARSVTALHEAALLR
                     AEGRPLTPLYEDVEVCRAAFARLAGVPVTRVALGASVAAHTGVIAASLPAGAEVLTAED
                     DFTSVLNAFHVRGDLKVRTVPLERIAESVRPGTALVAVSAAQSADGRIADLPALREAAR
                     THGARTYVDFSQAAGWLPMDADAYDFAAAVSFKWLLGPHGTAFLVVPEDFGGLTPLLAG
                     WVAAEKPWDSCYGPVAEYARSARRFDLTHALFTFAGLRRSLELIEELGVAAVHAHDVAL
                     ADRFRAGLAMLGHEPVPAPGSAIVSVPGLGVRQPELSEAGIEVSNRAGNLRAAFHLYNT
                     AADVDRLLDVLSD"
     aSDomain        complement(6495..7364)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS21900_Aminotran_5.1"
                     /evalue="1.10E-25"
                     /label="AMK31_RS21900_Aminotran_5.1"
                     /locus_tag="AMK31_RS21900"
                     /protein_end="347"
                     /protein_start="57"
                     /score="82.3"
                     /tool="antismash"
                     /translation="VEVCRAAFARLAGVPVTRVALGASVAAHTGVIAASLPAGAEVLTA
                     EDDFTSVLNAFHVRGDLKVRTVPLERIAESVRPGTALVAVSAAQSADGRIADLPALREA
                     ARTHGARTYVDFSQAAGWLPMDADAYDFAAAVSFKWLLGPHGTAFLVVPEDFGGLTPLL
                     AGWVAAEKPWDSCYGPVAEYARSARRFDLTHALFTFAGLRRSLELIEELGVAAVHAHDV
                     ALADRFRAGLAMLGHEPVPAPGSAIVSVPGLGVRQPELSEAGIEVSNRAGNLRAAFHLY
                     NTAADVDRL"
     gene            complement(7644..8357)
                     /locus_tag="AMK31_RS21905"
                     /old_locus_tag="AMK31_21605"
     CDS             complement(7644..8357)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989367.1"
                     /locus_tag="AMK31_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21605"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_073942277.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYVGKARFEKALAAFPHRDEVEVVHRSFELDP
                     GRAKGDTGPVIPMLARKYGMSEEQAQAAEDNLGAQAAAEGLAYRTRGRDHGNTFDMHRL
                     LHHAKQYGRQGELIQLLYEANFAEEQSVFDDTERLVEIAVAAGLDAAEARTVLADPDAY
                     AAEVRADEQEAAQLGATGVPFFVLDRKYGISGAQPADVFTQALTQAWGERSPLTLIDQG
                     DADACGPDGCAVPQH"
     gene            complement(8450..8944)
                     /locus_tag="AMK31_RS21910"
                     /old_locus_tag="AMK31_21610"
     CDS             complement(8450..8944)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019329308.1"
                     /locus_tag="AMK31_RS21910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21610"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_198948534.1"
                     /transl_table=11
                     /translation="MVSNRVRACPVIRTAVPAEVGTLVALHARARATYYPDGIPDDGAD
                     WSAAWRAAVERPDGHVLCAVEGGRVVGLASFRTPEDTGAETVKLFQFHVDPGHWRTGVG
                     TALHAACVEQWRAERRRTAVLDVHADNTRAQAFYARQGWEPDPDGEPGHHLRLRFPVDG
                     K"
     gene            complement(8978..9586)
                     /locus_tag="AMK31_RS21915"
                     /old_locus_tag="AMK31_21615"
     CDS             complement(8978..9586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436202.1"
                     /locus_tag="AMK31_RS21915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_21615"
                     /product="DUF1349 domain-containing protein"
                     /protein_id="WP_073942278.1"
                     /transl_table=11
                     /translation="MDVELPELPFPLRTYGPDGHWSYEDGVLTGWAGPRQDRFVPPTGE
                     ALEPAGDAPRLLGAPEGDFQLIARVTVGFGAAFDAGVLYVHVGERAWAKLCLEYSPDVP
                     AVCTVVTRGHSDDANSFTVEGSSVWLRVSRTGRAFAFHASRDGERWTFVRLFTLGEEKE
                     TGAALVGFMTQSPMGEGCVVTYDHIGFRPDWPEDLRDGS"
     misc_feature    10270..10285
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.0"
                     /tool="antismash"
ORIGIN
        1 ccggaaggac tgcgggagga tgatcgagac catcgcccgc gcgtgggaga agcccagcga
       61 acgggcggcc tccatctgtc ccttggggat ggcctggatg cccgcgcgga acgtctccgc
      121 catgtaggcg gcggcgacca ggccgagcgc gagggcgacc ttgccgtagg tgccgccgac
      181 gatctccgtg ccggggaagg ccagcgggac ggccaccccg atgaagatga agatcagcag
      241 ggcgggcagg ccgcggaaga tctcgatgta gacgccggcg agccagcggt acggacccac
      301 ggacgacagc cgcatcagcg cgatgaccat gccgagcacc aggccgacgg cgaagccgga
      361 cacggtgtag agcacggtgt tcttcagcgc cagcgtgatg acctcgggga acatctgctc
      421 cgcgatgtcc cgctgggcga actggttggc cagccggccc cagtcggccg cgaccgcgaa
      481 ggcgatcacg gccgcgacga agacgacgta ctggacgccg cgcgagatgc tgcgcttctg
      541 gcgccggctc aggcccttcc gcttcggcag gaccgctgtg tccgggctcg tcatgaggcg
      601 gacggggagg ccgcggactc gtcgtacggg ccgatccact gctcgtacag cttcttgtac
      661 gtgccgtccg ccttggcgtc cgcgatcgcc ttgttgatgg cctcgcgcag cttgtcgttg
      721 cccttcttga ccgtgaagcc gtactgctcg ccggtgttga tctgctcggc gacctcgaag
      781 gcgtcggcgt tggccttgtc cttcagccag ccctggacga ccgggtagtc gatgacgacc
      841 gcgtcgacct ggccggtgcg caggccgttg aggacggcgt cggaggactc gaaggagacc
      901 gggtcgaggc cctggctctt ggcgtagtcc tcacccgtgg tctgcgcctg ggcgccgacc
      961 ttctcgccct tgaggtcggc gacggaggag atgccgctgt ccttgtcggc gaggacggcc
     1021 tgggtggcgt cgaagtacgg gtccgagaag tcgacgttct tcttgcgctc ctcggtgatg
     1081 gtcatgccgg cggcggcgag gtcgcactcg ccggagttga ggaacgcgcc ggtcttgaag
     1141 ttctcgaacg gggtgtcgac gatgtcctgc ttcacgccga ggtcgtcggc gaccaggtcg
     1201 atcagggcga cgtcgaagcc ctgcaccttg ccgtcgatct ccgactggaa cggcgggtac
     1261 ggcaggtggg tgcaggtggt gagctgcccg gccttgacga gctcgacgcc gccggcggcc
     1321 gtcttggtgc cgccttcgcc gttgtcgctg gacgtgcagc cggccaggag gacgagtccg
     1381 gccgtcgcgg tggtggcggc cagggcgcgg gcccggcgcc cgaggacggt gttcacgggg
     1441 acctcctgtt aagggaactg agagttccga ttataaggaa atgtttgggc cactcaaatc
     1501 aaaccgatgg ttgtgagcgg gttcgaccta agaagtcggc accggggtgg gtcaggggcc
     1561 gggacagggg gctgccggag ggcgtgtcag ggctaccctc gactgcgtcc gcccgtgggc
     1621 gaagtccgcg tccaccccgt gagcgaagag agcaccgccg tgacccaccc gttcctcgac
     1681 ctgcccccgc tgaccgccgc gcggttcgcc gccatcgagg accgggtcgc ccggctgctc
     1741 ggcacccggc aggacgtcgt gatcatgcag ggtgaggcac tgctgccgct ggagggggcc
     1801 atccgggcca ccgcgggacc gggcaccacc gcgctgaacg tgatcacggg cccctacggg
     1861 cagaccttcg gcgactggct gcgggactgc ggggcgacgg tccacgacct ctccgtgccg
     1921 ttccacacgg cggtcagcgc cgagcagatc cgcaaggcgt tcgccgagca ccccggcatc
     1981 gacttcgtgt cgctggtgca cgccgaggcc gcgaccggca acaccaaccc ggtcgccgag
     2041 atcggcgagg tcgtccggga gcacggcgcg ctgttctacc tggacgcggt cgcctccgtc
     2101 ggcgccgagc cggtgctgcc ggacgcgtgg ggcgtggacc tgtgcgtgat cggggcgcag
     2161 aaggcgatgg gcggcccggc gggcgtgtcc gcggtgtcgg tgagcgagcg ggcgtgggcc
     2221 cggatggcgg cgaacccgca ggcgccgcgc cggtcctacc tctccctcct cgactggaag
     2281 gagcgctggg tcgacggcgg ccgcaaggcg ctgctgcacg cgccggcgca gctggagatg
     2341 ctggcgctgg aggcgtgcgt cgagcggatc gaggcggagg gcctggagac ggtgatggcc
     2401 cggcaccggt ccgccgcgtc ggcgacccgc gcgggcgcgc tggccctcgg cgggggcctg
     2461 gagccgtacg tccacgacgc ggcggaggcg gccccggtgg cgacgacgct gcgcgccccg
     2521 tccggcgtgg cggcctccga cctggtcgcc cgtgccctgg cgaccgaccc cgcgctgccg
     2581 ctggccgcgg gcggcggcgc gctggcccgg gagatgatcc gcgtcaacca ctacggcccc
     2641 gacgccgccc cgggcaccat ccaggcggcc ctcgcggccc tgggcgcggc actggccgaa
     2701 cagggcctcc cggtggaccc ggacgcggcc cgccgcgcgg cggaacaggc ctggcactga
     2761 gcgaccaggg gtccgggagc ccgcccccgg accccgggcc atttcatcga ggaacgtatt
     2821 gacgggctta tcggggcttg aattcattct cttttcgaaa tcaaatccgg ggtagcttcc
     2881 cgtattcttc tgccccgttt ccccaaccct aaacgcgaag attctgcgaa caccgaacgg
     2941 gtcgttccgg gcagatctcg cgagggttac acgggtgtga cgcgttacac accgcgcccg
     3001 ttttgcgaag tgaatcccgc acaaattcgg gcatctccca gcggtctcgc gcgatcaccc
     3061 gcgcccgcgt gataacacac gaccgcgcca cacccaagcc ctttccccca tgcaattttg
     3121 aatttcgctc gctaaattca atccgcatga ctgccgcaca agcagaccta cacatcgacc
     3181 gcccgtcggt ggcggacgga gccgctttct ggcggctcgc caaggaatcc ggaaccctcg
     3241 acctgaactc ctcctacagc tatctgctgt ggtgccggga cttcgccgcg acctccgcgg
     3301 tggcccgtga cggcgacgga gaacccatcg ggttcgtcac cgggtatctg cggccggacc
     3361 gtccgcggac cctgctcgtc tggcaggtgg ccgtcgacgc cgcgcaccgc ggccgcggga
     3421 tcgcggcccg gctgctcgac gggctggccg cccgggtggc ggccgagcgc gaggtcatct
     3481 gcgtggagac caccatcacc ccgggcaaca ccgcctcgca gcggctgttc acctccttcg
     3541 cggagcgcca cggcgcccgc gtggagcgcg aggtcgtctt cgacacgccg ctgttcccgg
     3601 acggcccgca cgaccccgaa gtcctgtacc gcatcggccc gttgaccccc cacctctcgc
     3661 actgaggagc gattcgtcgt gaccatcacc cagcccgacc tgagcgtctt cgagaccctg
     3721 gagtccgagg tgcgcagcta ctgccgcggc tggcccaccg tcttcgaccg ggcgcacggc
     3781 agccgtatgt acgacgagga cggccacgag tacctggact tcttcgccgg agccgggtcg
     3841 ctcaactacg gccacaacaa cccggtcctg aaacgggcgc tgctcgacta cctggagcgg
     3901 gacggcgtca cccacggcct ggacatgtcg accaccgcca agcggtcgtt cctgcagacc
     3961 ttccaggacc tggtgctgcg cccgcgggac ctgccgtaca aggtgatgtt cccgggcccg
     4021 accggcacca acgcggtgga gtccgcgctg aagctggccc ggaaggtgaa ggggcgcgag
     4081 gcgatcgtgt ccttcaccaa cgccttccac gggatgtccc tgggctccct cgccgtcacc
     4141 ggcaacgcct tcaagcgggc cggcgccggc atcccgctgg tgcacggcac gccgatgccg
     4201 ttcgacaact acttcgacgg ccgggtgccg gacttcctgt ggttcgagcg gctgctggag
     4261 gaccagggct ccgggctgaa caaacccgcc gccgtgatcg tggagaccgt gcagggcgag
     4321 ggcggcatca acgtggcccg cccggagtgg ctgcgcgcgc tcgccgagct gtgcgagcgg
     4381 caggacatgc tgctcatcgt cgacgacatc cagatggggt gcggccgtac cggcgccttc
     4441 ttctccttcg aggaggccgg catcaccccg gacatcgtca ccgtctccaa gtccatcagc
     4501 ggctacggcc tgccgatgtc gctgtgcctg ttcaagcccg agctggacgt gtgggagccg
     4561 ggcgagcaca acggcacctt ccgcggcaac aacccggcgt tcgtcacggc caccgccgcc
     4621 ctggagatgt actggaccga cggctccgcc atggagaagc agacccggtc gcgcggcgag
     4681 caggtcgagc aggcgctgat cgccgtcacc gaggagaacc tggccgacgt caaggagtac
     4741 cgcggccggg gcctggtgtg gggcctggag ttccacgaca aggaccgggc cggccgggtg
     4801 gcgcgccgcg ccttcgagct ggggctgctg atcgagacct ccggcccgga gagcgaggtc
     4861 gtcaagctgc tgcccgcgct gaccatcact cccgacgagc tggacgaggg gctgacgacc
     4921 ctcgcccgtg ccgtccggga aaccgcctga ccacatctcg aaacccgccg accgcactat
     4981 ccaggaggca tcgcaacacc gtgatcgtcc gttcgttcaa ggacatcgaa ggcaccgacc
     5041 ggcatgtgaa ggccgcgtcc gggacgtggg agagcaaacg catcgtcctc gccaaggaga
     5101 gggtcggctt ctccctgcac gagacgatcc tctacgcggg cacggagacg tccatgtggt
     5161 acgccaacca catcgaggcc gtggtctgcg tcgagggcga ggccgagctg accgaccacg
     5221 agaccgggcg gacgtacacc atcacgcccg ggaccatgta cctcctggac ggccacgagc
     5281 ggcacacgct caaggtcaag gaggacttcc gctgcgtctg cgtgttcaac ccgcccgtga
     5341 ccggccggga ggaccacgac gagaacggcg tctacccgct gctcaccgag cccgaggagg
     5401 tgtgacatca ccatgaccac gaccacgacc acgaccacca ccgcgaccgt caccgatctc
     5461 tacccgaccc gcggcgccag tgaggtgctg gtcccgcgcc aggacccggt cgtctgggct
     5521 gcgccggacg cccccggccc gatcgggccg gacggcctgc aggccttcga gcgcgacggc
     5581 ttcctcgcca tcgaccagct catcaccgag gacgaggtcg ccgtctaccg gcaggagctg
     5641 gagcggctgg tctccgaccc ggcgatccgc gccgacgagc gctccatcgt cgagccgaag
     5701 tcgcaggaga tccgctcggt cttcgaggtg caccggatca gcgaggtgtt cgcgaacctg
     5761 gtgcgggacg agcgggtcgt cggccgggcc cggcagatcc tcggctcgga cgtctacgtc
     5821 caccagtcgc ggatcaacgt caagcccggc ttcggcgcca gcggcttcta ctggcactcc
     5881 gacttcgaga cctggcacgc cgaggacggc ctgccgaaca tgcggacggt gtccgtctcg
     5941 atcgcgctga ccgagaacta cgacaccaac ggcgggctca tgatcatgcc cggctcgcac
     6001 aagacattcc tgggctgcgc gggcgccacg ccgaaggaca actacaagaa gtccctgcag
     6061 atgcaggacg cgggcacgcc ctccgacgag gcgctgacca agctggcctc cgagtacggc
     6121 atccggctgt tcaccggcaa ggccggctcg gcgacctggt tcgactgcaa cgccatgcac
     6181 ggctccggcg acaacatcac gccgttcccg cgcagcaacg tgttcatcgt gttcaacagc
     6241 gtggagaaca cggcggtcga gccgttcgcg gccccggtac gccgaccgga gttcatcggg
     6301 gcgcgggact tcacgccggt gcggtgaacc cggccggggg tccgggggtt gcccccggga
     6361 gacacagcat cggggctcgg gacttcacgc cggtgcggtg aacccggcgg cgctgaggtg
     6421 acatacggga gcgggcggtg ccttcacggc accgcccgct cccgtgtgcg cgttcagtcc
     6481 gacagcacgt ccagcaggcg gtccacgtcg gcggccgtgt tgtagaggtg gaaggcggcc
     6541 cgcaggttgc ccgcgcggtt cgacacctcg atgcccgcct cgctcagttc cggctggcgg
     6601 acgccgaggc cgggcaccga gacgatcgcc gatccggggg cgggcacggg ctcgtggccg
     6661 agcatcgcga gcccggcccg gaaccggtcg gcgagcgcca cgtcatgggc gtgcaccgcg
     6721 gccacgccca gctcctcgat cagttcgagt gagcggcgca ggccggcgaa ggtgaacagc
     6781 gcgtgggtga ggtcgaaccg ccgcgcgctg cgggcgtatt cggccaccgg cccgtagcag
     6841 ctgtcccacg gcttctccgc cgcgacccag ccggccagca gcggggtcag cccgccgaag
     6901 tcctcgggaa cgacgaggaa ggccgtgccg tgcgggccga gcagccactt gaaggagacg
     6961 gccgcggcga agtcgtaggc gtcggcgtcc atcggcagcc agccggcggc ctgggagaag
     7021 tcgacgtagg tgcgcgcccc gtgggtgcgg gccgcctcgc gcagggcggg caggtcggcg
     7081 atccgtccgt cggccgactg ggcggcgctg accgcgacca gcgcggtgcc ggggcggacg
     7141 gactcggcga tccgctccag cgggaccgtg cggaccttga ggtcgccgcg gacgtggaac
     7201 gcgttcagca cggaggtgaa gtcgtcctcg gcggtgagga cctcggcgcc ggcgggcagg
     7261 gaggcggcga tcaccccggt gtgcgcggcg accgacgcgc cgagggcgac ccgcgtcacc
     7321 gggaccccgg ccagccgggc gaaggcggcc cggcagacct cgacgtcctc gtacagcggg
     7381 gtcagcggcc tgccctcggc ccgcagcagg gccgcctcgt gcagggcggt gacgctgcgg
     7441 gcgggcagca ggccgttgct cgcggtgttc aggaaggtgg acttgggggt gaactcggcg
     7501 cggaccaggc tgtcgaaggt ctccgtgggc tccatggctc cactgtgcgg cccggtgacc
     7561 tcgccgtcca ttgcgaattt ctgttgacga cgtcccagtg ttgcttatgc atccgcgccg
     7621 acctgcggtt ttgccggccc ggctcagtgc tgcggcaccg cgcagccgtc cgggccgcac
     7681 gcgtcggcgt ccccctggtc gatgagggtg agcggggagc gctcgcccca cgcctgggtg
     7741 agggcctggg tgaagacgtc ggcgggctgg gcgccggaga tgccgtactt ccggtcgagg
     7801 acgaagaacg gcacgccggt ggcgccgagc tgggcggcct cctgttcgtc ggcgcggacc
     7861 tcggcggcgt aggcgtctgg gtcggcgagc accgtgcggg cctccgcggc gtccagcccg
     7921 gcggcgacgg cgatctccac gagccgttcg gtgtcgtcga agacggactg ctcctcggcg
     7981 aagttggcct cgtacagcag ctggatcagc tcgccctgcc ggccgtactg cttggcgtgg
     8041 tggagcaggc ggtgcatgtc gaaggtgttg ccgtggtcgc ggccgcgggt gcggtaggcc
     8101 aggccctcgg cggcggcctg cgcgcccagg ttgtcctcgg cggcctgcgc ctgctcctcg
     8161 gacatgccgt acttgcgcgc gagcatcggg atgacggggc cggtgtcgcc cttggcgcgg
     8221 cccgggtcca gctcgaagga gcggtgcacc acctcgacct cgtcgcggtg cgggaaggcc
     8281 gccagcgcct tctcgaagcg ggccttgccc acgtagcacc aggggcaggc gatgtcgctc
     8341 cagatctcga cgcgcatgtt ctccgctctc cagctcggtt cactgtgcgg agactccctc
     8401 cgcgaaggta tgtgaacctt caaacggctg gattcattcc cgccgcgact cacttcccgt
     8461 cgaccgggaa gcgcagccgg agatggtgac cgggctcccc gtccgggtcg ggctcccagc
     8521 cctgccgggc gtagaaggcc tgggcacggg tgttgtcggc atgcacgtcc aggacggccg
     8581 tgcgccgccg ctcggcccgc cactgttcga cgcaggcggc gtgcagggcc gtcccgaccc
     8641 cggtgcgcca gtggccgggg tcgacgtgga actggaacag cttgaccgtt tccgcaccgg
     8701 tgtcctccgg tgtccggaag gaggcgaggc cgaccacccg cccgccctcg acggcgcaca
     8761 gcacatggcc gtccggccgc tcgacggcgg cccgccaggc ggcggaccag tcggcgccgt
     8821 cgtccgggat cccgtcgggg tagtaggtcg cccgggcacg ggcgtgcagc gcgacgaggg
     8881 tgccgacctc ggcgggcacg gcggtgcgga tcaccgggca ggcgcggaca cgattgctga
     8941 ccatgccacg gaagacggga ttccgccggt cccggtttca gcttccgtcg cgcaggtcct
     9001 cgggccagtc cggccggaac ccgatgtggt cgtacgtcac cacacagccc tcccccatgg
     9061 gcgactgcgt catgaagccg acgagggccg ccccggtctc cttctcctcg ccgagcgtga
     9121 acagccggac gaaggtccac cgctcgccgt cccgggaggc gtggaaggcg aaggcgcgcc
     9181 cggtccggct cacccgcagc cagaccgaac tgccttccac ggtgaaggag ttggcgtcgt
     9241 cggagtgtcc ccgggtgacc accgtgcaga cggcgggcac gtccggggag tactccaggc
     9301 agagcttggc ccacgcccgt tcgccgacgt ggacgtagag caccccggcg tcgaaggccg
     9361 cgccgaaccc gacggtgacc cgcgcgatca gctggaagtc cccctcgggc gcccccagca
     9421 gccgcggcgc gtccccggcg ggctccagcg cctccccggt gggaggcacg aaccggtcct
     9481 gccggggccc ggcccacccg gtgagcacgc cgtcctcgta ggaccagtgc ccgtcggggc
     9541 cgtatgtgcg aagggggaag gggagttcgg gaagctcgac gtccatgact gcattctcca
     9601 cggggcggtg accgtcctcg ggggaacccc gcaccccggc gctaccgctc cagcaccccg
     9661 ttgaaccgcc ggggcagccc cagcggattc tcgtcccgca gctccgcggg gagcagcgcg
     9721 gccggcgtcc cctggtacac gaccggccgc agccaccgct cgatggcggt cccgcccacc
     9781 gacgtggagg tcgaggtcgt cgcggggtag ggcccgccgt gatgctgcgc cggtgccacg
     9841 gcgacccccg tcggccaccc gttgaccagc acacgcccgg cgagcggggt cagctcggcg
     9901 aggatctcgg cgccccgccc ctcaccggcg gcctccccgg aggacaggtg cacggtcgcc
     9961 gtgaggttcc cgggcagccg cgacagaacc gccttggcct ctccctcgtc ctggtagcgg
    10021 gcgacgacgg tcaccggccc gaagcactcc tcgagcagca ggtcgtgctc gccctcccgg
    10081 gccagcttct ccgccggcac ggtcaggaag cccgggctga cggtgtgctc cccgccctcg
    10141 cccggcgtca ccggggcctc cacgtccggc agttcggccc gctcggcgac cccggcgacg
    10201 aagttgtccc gcatccggtg gtcgagcagc accccggcgt cgacggcgct caccgcgtcc
    10261 gtgagcgact tgacgagctg gtcgcccgcg tcaccggccg gggcgaggac caggcccggc
    10321 ttcacacaga actggccgac gcccagggtc atcgacccgg cgagcccgga gccgatggcg
    10381 tcggcgcgtt cggccgccgc ggcct
//
