LOCUS       NZ_LIVZ01000003        23650 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0107 scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_LIVZ01000003
VERSION     NZ_LIVZ01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0107
  ORGANISM  Streptomyces sp. TSRI0107
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 743720)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743720)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905845.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,745
            CDSs (total)                      :: 7,667
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 200
            CDSs (without protein)            :: 200
            Pseudo Genes (ambiguous residues) :: 0 of 200
            Pseudo Genes (frameshifted)       :: 85 of 200
            Pseudo Genes (incomplete)         :: 158 of 200
            Pseudo Genes (internal stop)      :: 13 of 200
            Pseudo Genes (multiple problems)  :: 51 of 200
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:19:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 457801
            Orig. end                         :: 481451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVZ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23650
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(micKC and not PKS_KS)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..23650
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-iii"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22592
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22592
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12592](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12592
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(1002..1017)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(1012..1027)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            1061..2290
                     /locus_tag="AMK31_RS09005"
                     /old_locus_tag="AMK31_08880"
     CDS             1061..2290
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_28"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676700.1"
                     /locus_tag="AMK31_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08880"
                     /product="glycosyltransferase"
                     /protein_id="WP_073940132.1"
                     /sec_met_domain="Glyco_transf_28 (E-value: 1.2e-13,
                     bitscore: 46.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGSRGDVAPYTGLGRALSRAGHQVTLVTHGAFEPLVADSGLGF
                     HALPVDPRAELETSRGRGLHRSASGVGKLLRVVGMARALVGRMTDDLLAAARTSEVLLL
                     SSSLAPLGHTLAEGLRLPSMGVYLQPLAATGEFAPPVLGAGSWGGVGNRLAGHGVGAAV
                     ERVFSGAVPAVRARLGLPALGPGAARRAREKRNWPILHGFSPLVVPRPRDWRAGLEVTG
                     YWWPYDRDLRLPAGLRDFLDAGPPPVFVGLGSATVPDPAGLSAGIVAALRRAGLRGVIQ
                     RGWGGLAADGDDMLTVGEVPHAALFPRMAAVVHHAGAGTTAAGVRAGVPAVPVPVQFDA
                     GFWAARLVALGVAPRALPLRRVTADALAAALVEATRDAGYRERARALGSRVRAEDGTAA
                     VVERVNRLRG"
     gene            complement(2368..4341)
                     /locus_tag="AMK31_RS09010"
                     /old_locus_tag="AMK31_08885"
     CDS             complement(2368..4341)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655786.1"
                     /locus_tag="AMK31_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08885"
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
                     /protein_id="WP_073939854.1"
                     /transl_table=11
                     /translation="MHLLNLGILAHVDAGKTSLTERLLHSAGVIDEIGSVDAGSTRTDT
                     LALERQRGITIKSAVVSFPLDGVTVNLIDTPGHPDFIAEVERVLGVLDGAVLVVSAVEG
                     VQAQTRVLMRTLRRLRIPTLLFVNKIDRRGAAYEDVLRAAAERLSAAVVPMGTATGLGT
                     PGARFTPRPVPAALDVLADHDDDLLAAYVDGRVPDALVRAALAEQTRQGLVHPAYAGSA
                     ITGAGVDALIDGIGRLLPTAGGDPDGPVSGTVFKVERGPAGEKVAYARLFSGTLRTRDR
                     IRFGARGREGRVTAVHVFEDGTDVRRDAVGAGRIARLWGLGEVRIGDWLGVPRTTDGHL
                     FAPPTLETVVEPVRPADRRALHLALTQLAEQDPLIGLRHDEVRQETSVSLYGEVQKEVV
                     QATLADDYGLDVAFRETTPLCVERLTGTGAAVEFIKKDDNPFIATVGLRVDPAPVGAGT
                     QFRLEVELGSMPYAFFKAVEDTVRETLGQGLYGWRIPDCTVTMTHSGYWPRQSHAHQGF
                     DKSMSSTGADFRGLTPLVLAEALRRAGTRVHEPMHRFRLEAPADTLGALLPVLSALRAV
                     PRTTETRGALCVLDGVVPAALVHALEQRLPGLTRGEGELESAFDHYAPVDRGAAVPRRP
                     RTDHNPLNRKEYLLNLTGRTAS"
     gene            4498..5601
                     /locus_tag="AMK31_RS09015"
                     /old_locus_tag="AMK31_08890"
     CDS             4498..5601
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988901.1"
                     /locus_tag="AMK31_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08890"
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_073939855.1"
                     /transl_table=11
                     /translation="MRDILPVLSGWYAAAEPFGLATVVAVSGSAPRDPGAAMAVGPGGE
                     AVGSVSGGCVEGAVFELAREVAASGRARLEKFGYGDEDAFAVGLTCGGEITVLVRPVSP
                     GHDPSFGAVAASVAGGRPVTVATVTDGPAPRGATLAVWPGEVSGTLGTSGLDAAVTADA
                     RGELALGATGVRHYGPRGERRADEVSVFLHSFAPPPRMLVFGAIDYAAAVARIGVFLGY
                     RVTVCDARPVFATPERFPPGVEVVVDWPDRWLRGTGTDERTVICVLTHDPKFDVPLLAE
                     ALRRPAAYIGAMGGRRTHDERARKLAGAGVGAAELARLRSPIGLALGARTPEEVAVSVA
                     AEIVALRRGGSGTPLAATTGAVHPPRP"
     gene            complement(5604..6113)
                     /locus_tag="AMK31_RS09020"
                     /old_locus_tag="AMK31_08895"
     CDS             complement(5604..6113)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040481.1"
                     /locus_tag="AMK31_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08895"
                     /product="metallophosphoesterase"
                     /protein_id="WP_073939856.1"
                     /sec_met_domain="Metallophos_2 (E-value: 3.7e-28, bitscore:
                     93.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLLMSDTHVPKRARELPAPLLAELPRADVVFHAGDWVDTATLD
                     LLERHSRRLVAVYGNNDGPELRARLPEVAHAELGGLRFGAVHETGPAQGRETRCAARFP
                     DLDVLVFGHSHIPWDTTAPSGLRLLNPGSPTDRRRQPHCTYMTATVADGELTDVTLHRL
                     PPRRDR"
     gene            complement(6136..6315)
                     /locus_tag="AMK31_RS41420"
     CDS             complement(6136..6315)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823378.1"
                     /locus_tag="AMK31_RS41420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_073939857.1"
                     /transl_table=11
                     /translation="MTTPTSDKPVARRPETGWSRARRMKEKPALRTCVSAVRDPEGPAR
                     PDLALEGNIVRGED"
     gene            complement(6387..6743)
                     /locus_tag="AMK31_RS09030"
                     /old_locus_tag="AMK31_08900"
     CDS             complement(6387..6743)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569985.1"
                     /locus_tag="AMK31_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08900"
                     /product="DUF6479 family protein"
                     /protein_id="WP_073939858.1"
                     /transl_table=11
                     /translation="MNTTASEVAASGSGVGMAVILVGGVVITAALIWAVLLGIRARKRE
                     PRRPRPDEQPRLPDSGPVHETREQRAPHGMGEGERLTPHELRPTGGTPSGDQRRPRWDE
                     GSSGSFGGGGSGAT"
     gene            complement(6885..7304)
                     /locus_tag="AMK31_RS09035"
                     /old_locus_tag="AMK31_08905"
     CDS             complement(6885..7304)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823379.1"
                     /locus_tag="AMK31_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08905"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_073939859.1"
                     /transl_table=11
                     /translation="MTQHVRDIMTADPVTVEPQTSVAAVARIMRDEDIGAVLVTEGDDL
                     RGLVTDRDLVVRSISEGGDPEQTTVAGACSEDLFTLQPDEDLDNAIQLMREHAVRRVPV
                     VEQGHPVGIVSLGDLAMERDPGSALGDISVARPNT"
     misc_feature    complement(7269..7283)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(7351..9795)
                     /locus_tag="AMK31_RS09040"
                     /old_locus_tag="AMK31_08910"
     CDS             complement(7351..9795)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068579.1"
                     /locus_tag="AMK31_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08910"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_073939860.1"
                     /transl_table=11
                     /translation="MVNDGAAGRGTVTPRAEIALRAITDDRDTPERLHRVLEQSLVFAG
                     ATFAAVYAPDEDGDLLCLVESAGVPRTLYGLRDSYPVAGRSPAADAHRDRRPVWVSPAE
                     LAARADSRRTPGPEFHLAALPASRDTHGGCLLAVSEDPHGFDTDQRKALELIADAVTCP
                     APPAHPEGGELPPHAFALAMDTGRVEVGDGILDLFGLTRDDFDGKVETLLGLTVPEDLP
                     SLMSVVEADHMSVGDRELEFRVRRPAGPPRWLRLRGRMQPGGEGQQARLVGTVVDASQL
                     RSDVTDVARVQRLAAALSTAGTVRDVSQAVVAALRRPLRADRIALAELEHDRLVVTVLD
                     PPEPEAWPELWRLEWRTEWPDAPVRAMPTLAAALREGRAQIWPSGTTLEPALADVGPGG
                     LAVLPLSAGGRMAGACLIGWDSPHDFGPDERALLTASAGLAGQALMRAHAFDAEHELVG
                     MLQRQLLPRRLPRLPGAEAVARYLPATAGLEVGGDWYDVIPLPDHHVALVIGDVQGHSP
                     AAATLMGQMRTALRAYAVEGHPPDVVVSHANRLLVDMETDLFATCAYVDVDMEEGTAWC
                     VRAGHLHPVLRHPDGSAQVVETEGGPPLGVLTQADFPMTPIRLQPGTLLALTTDGLVES
                     ADTDIDEGMDRFAQRLARSDPAHLGLVADGLLGNARRSDDVALLLMRYDGMAVRPRRET
                     WSVWRVPEAVRHARRFTKRTLRAWGVAAHADAVLLIVSELVTNALVHTEGPVRMDLTLV
                     GNRMRIAVADASPRTPVKPTSIGWEATGGRGLLLVEAMSAAWGTVPVSGGKQVWSELVL
                     EP"
     gene            10001..12592
                     /gene="lanKC"
                     /locus_tag="AMK31_RS09045"
                     /old_locus_tag="AMK31_08915"
     CDS             10001..12592
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128990.1"
                     /locus_tag="AMK31_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08915"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_073939861.1"
                     /sec_met_domain="micKC (E-value: 1.3e-232, bitscore: 769.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.4e-10, bitscore: 36.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.8e-06, bitscore:
                     21.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADGHFYDTPDRLTGDGHTAAPLYAVARREVPEGWR
                     AARTGDWLTMTPLDADGEPLPGPAQGWKIHASATRANAERIAEIVWDYCVPRRIPFKFV
                     PAAHLLHLRNAKYAPREGSGKFVTVYPVDEEQLRLVLTELGALLKGFEGPYILTDLRWD
                     DGPLHVRYGAFARSYVVDERGSLVPAVRDGEGRLVPDRRDPSFRVPEWVTLPDFLAPQL
                     AARNATTVGDLPYRIEKALHFSNGGGVYAGTDTRDGRRVVLKEGRPHAGLAADGADAIA
                     RLEREKRALEQVAGTGVVPEVRDWFTLGEHRFLVMDFVEGRPLNSFFAERHPLLVPDPD
                     PRAVADYTAWALRIHRAVERAVDAVHERGIVFHDLHVFNIMVAPDEESVFLLDFEAAAP
                     VAENGRQVVAHPGFFAPPDRRGADVDRYALACLRLALFMPVTTLFVIDRGKAAHLAEVI
                     AEQFPDVPRAFLDEAVAEITRDAAGPARGGSARLVEPADWPHSRDSMVKAILASATPER
                     TDRLFPGDIAQFSDGGGLGLAHGAAGVLHALAETGAQRYEEGERWLLDRTAPPPAGTPL
                     GLYDGLAGVALVLDRLGHRQRALDLVDGILRERWQNLSSDLHGGLAGLGLVLGHLAGTT
                     GEPGLRERADEAAEIVVRRLAEPLPEAPRRRAGLLRGATGQALFLLRRHEATGDGELLA
                     AAGRALRRDLASCVVREGGALEVDEGWRTLPYLGDGSVGLGMVIDDYLAHATDDTGELE
                     RARAGVLTAATCRFYAQPGLFQGRAGMILHLGRTTAPGADVRARLAEQLAGLGWLAMPY
                     QGQLAFPGHQMMRLSMDLATGTAGCLLALGAALGDTPAALPFLPPPAGRPS"
     gene            12671..12787
                     /locus_tag="AMK31_RS09050"
                     /old_locus_tag="AMK31_08920"
     CDS             12671..12787
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="AMK31_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08920"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_073939862.1"
                     /transl_table=11
                     /translation="MALLDLQTMEADEHTGGGGASTVSLLSCISAASVLLCL"
     CDS_motif       12671..12733
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMEADEHTGGGGAS"
                     /locus_tag="AMK31_RS09050_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12734..12787
                     /prepeptide="core"
                     /locus_tag="AMK31_RS09050_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="27.00"
                     /molecular_weight="1603.0"
                     /monoisotopic_mass="1601.9"
                     /core_sequence="TVSLLSCISAASVLLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMEADEHTGGGGAS"
                     /leader_location="[12670:12733](+)"
                     /alternative_weights="1621.0"
                     /alternative_weights="1639.0"
                     /alternative_weights="1657.0"
     misc_feature    12678..12698
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            complement(12858..13463)
                     /locus_tag="AMK31_RS09055"
                     /old_locus_tag="AMK31_08925"
     CDS             complement(12858..13463)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386627.1"
                     /locus_tag="AMK31_RS09055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08925"
                     /product="response regulator transcription factor"
                     /protein_id="WP_073939863.1"
                     /transl_table=11
                     /translation="MIRVLLVHDSSLVRSVLAEWLSREPDLGVDDAPWQAAPGRARSLR
                     PDVCAADLDYTGRYGIPPLGELCGRGGERPPRLLVLATADRPGLLRRAVEAGALGYVDK
                     AGSPERLVRGIRCVAAGERFVDNTLGLGFLKASQIPLTRRELSVLSLAAEGASIAEIAG
                     SLHLSRGTVRNYMAAITRKTGARNRIDAIRISQGEGWL"
     misc_feature    complement(13332..13334)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     cand_cluster    13435..23650
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    13435..23650
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18434:18650](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      18435..18650
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     misc_feature    complement(13551..13568)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            13753..15900
                     /locus_tag="AMK31_RS09060"
                     /old_locus_tag="AMK31_08930"
     CDS             13753..15900
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117170.1"
                     /locus_tag="AMK31_RS09060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08930"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_073939864.1"
                     /transl_table=11
                     /translation="MVGVDDGQPHTRAPAAERQPAGEPLLSLALAAMLDGVHAHSGAVY
                     LLSPDGQVLEMAVMAGLPRAFSAPWERVGVGAPIPVAEAVRERRLVWVGGEEEMARRYP
                     RVAVVLPYPFALAAVPVVTGGTVYGAVFVTWPGSHAPALTDRIREQLTSACDRLALRLE
                     RAARESRPVLPEPDLLAAPVVGGTPGTIGAVEAARMVSRLPYGLCSLDIHGRVAFANPA
                     AAELIGEPVSRLVGTQLWASVPWLNDPVYEDRYRAALFSQHATSFVALRPPGEWLSFRL
                     YPSTSGLSVRITRARSVSPTGQAEPSAGEGPSRLVTISQVLTLASALTEAVGVQDVVQL
                     VADELAPAVGSHALVLLASRGGRLRVLGHRGYPDPRLVERFDGTPLGSATPGAHALHTG
                     VPAFFESREELERLYPARAESPDGFAAWAYLPLIASGRPVGTCVLAYSGPRHFAADERS
                     VLTSMAGLIALALERALLYDAKHQLAHGLQAALLPPSLPPLPGIDAAARYLPSTRGMDI
                     GGDFYDAVPSAGTAVAVIGDVQGHNVTAAGLMGQIRTAVRAYTAVGQSPQEVMGSTNRL
                     LIDLGTDLFASCLYLRLNPRHARAVMARAGHPPPLLRRPDGRVRVLDLAGGPLLGIDAS
                     AVYPTTEVDFAPGSVLVLYTDGLIESPGVDIEEALAALGELLTEAGRLPLDELADVLVG
                     QGAGAAERADDVALLLLRARG"
     gene            complement(15965..17362)
                     /locus_tag="AMK31_RS09065"
                     /old_locus_tag="AMK31_08935"
     CDS             complement(15965..17362)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430713.1"
                     /locus_tag="AMK31_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08935"
                     /product="S1 family peptidase"
                     /protein_id="WP_073939865.1"
                     /transl_table=11
                     /translation="MSHKRIPKRKAVLAAGGVAALGAAAILLPNANASQDGAPEAKSAP
                     RTLKSADASDLADQLAGLLGDAFAGSYYDADRQQLVVNVVGDDNQLVVQAKKAGAAVRQ
                     VENSAAELKAAAQTLKSEATIPGTAWAVDPRTNKVLVTADSTVTGAKWDTLESTVQSLG
                     SGMATLRKSNGTFKTFASGGDAIFGGGARCSLGFNVTAGDGTPAFLTAGHCGVAAQQWS
                     DAEGGAPIGTVDQAVFPGEGDFALVKYDDPATQAPSEVNAEGQTVPILQAAEATVGQEV
                     FRMGSTTGLADGTVTGLDATVNYPEGTVTGLIQTNVCAEPGDSGGSMFTQDGLALGLTS
                     GGSGDCTVGGETFFQPVTTALEAVGATLEGADGAGGAGADEGAGAGGEQEGAGGAEEGA
                     GGAQEGVGGAEEGVGGAEEGVGGAEEGAGDAQEGVGGEQAGAGEQAGGGDEAAEEAGDS
                     GLTQNHS"
     misc_feature    complement(17433..17449)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.54"
                     /tool="antismash"
     misc_feature    17557..17577
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            17568..17981
                     /locus_tag="AMK31_RS09070"
                     /old_locus_tag="AMK31_08940"
     CDS             17568..17981
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676669.1"
                     /locus_tag="AMK31_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08940"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_073939866.1"
                     /transl_table=11
                     /translation="MTMTTAEAEKILSVNFAPWVLELGLTVEALGDDRATLRLPWSGRL
                     AREGGALSGQALMAAADTATVIAVSAARGAFVPMTTVQQSTSFQRPVAEADVLITAVLT
                     KLGRRMAFADIAMTVEPGGDLAARASTVYAILG"
     misc_feature    complement(18188..18203)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     misc_feature    complement(18417..18433)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     gene            18435..18650
                     /locus_tag="AMK31_RS09075"
                     /old_locus_tag="AMK31_08945"
     CDS             18435..18650
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="AMK31_RS09075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08945"
                     /product="hypothetical protein"
                     /protein_id="WP_073939867.1"
                     /sec_met_domain="strepbact (E-value: 1.3e-37, bitscore:
                     123.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVETVEISDAELDNVAGGLHVNALGTVTGLVDGVAPVSGL
                     VDTVVGTVEGVTGLNTAPVTNLVAGL"
     gene            18752..19558
                     /locus_tag="AMK31_RS09080"
                     /old_locus_tag="AMK31_08950"
     CDS             18752..19558
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="AMK31_RS09080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08950"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_073939868.1"
                     /transl_table=11
                     /translation="MQFRQQALARLQSPEELDLPVRLARPQGWLVLSVTVVAMAAASVW
                     AVTGSVSSTVSAPAILTHGQGSYVLQSPVAGQVTEILAKEGERLPADAPVLKIRTAEGE
                     TVVRTLAAGRLTALAATIGQILATGANVAAVEKVAARDAPLYATVYVPAENASAIPADA
                     PVDLTVQTVPTQEYGVLRGHVKSVDRSPQTAQRIAAFLGDSQLGEQFTKDGRPVAVLVR
                     LDRSASTESGYAWSTTDGPPHALTSMTVATGSIRLADQRPVDWLLP"
     gene            19555..21777
                     /locus_tag="AMK31_RS09085"
                     /old_locus_tag="AMK31_08955"
     CDS             19555..21777
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040519.1"
                     /locus_tag="AMK31_RS09085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_08955"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_073939869.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.4e-38, bitscore:
                     126.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAEETRGRRRAAPPRRTVPGTRRRTVRTPTVLQMEAVECGAA
                     SLAMVLGHYGKHVPLEELRIACGVSRDGSRASNLLKAARGYGLTAKGMQMDLAALAEVR
                     APAVLFWEFNHYVVYDGMGRRFGRRGVWVNDPGKGRRFVSTEDFDGSFTGVVLVMEPGE
                     DFTRGGRRPGVLGAMPARLRGTAGTLPAAVLASLLLVLVGAALPALSRTYIDMFLIGGQ
                     TSLLDVLFASMGACVLLTLVLTWLQQANLHHGRIISSTLSSARFLRHLLRLPVTFFSQR
                     SPADLVQRLQSNDAVAETLARDLAAAGVDAVVVVLYAVLLYTYDPQLTFVGVGVALLNI
                     VAMRVVIRLRATRTAKLRADNARLTTTAYSGLQLIETMKATGGEDGYFRKWAGQHATTL
                     EEQQRLGVPSAWLGVVAPTLATLNSALILWIGGMRAIEGHISVGLLVAFQALVTRFTAP
                     LTRLNGVAGRIQDFAADVARLKDVENFRADPLYSRAGGESTRRLHGHVELENITFGYSP
                     LDKPLLTGFDLTVGPGQQVALVGGSGSGKSTVSRLIAGLYTPWEGVIRIDGQRLEDIPR
                     GALAASVSFVDQDVFLFEGTVRDNVALWDPSIPDDAVVEALRDAALYDVVMRRPGGIHS
                     RVEQDGRNFSGGQRQRLEIARSLVRRPSILVLDEVTSALDAETELVVMDNLRRRGCACV
                     VIAHRLSTVRDSDEIVVLQHGTVVERGRHEELVARGGAYAALVRER"
     misc_feature    23594..23607
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
ORIGIN
        1 gcgcgctgcg ggtgctcgcc cgggccgggt tcaggctgcc tgccgcgctc gccaacaacg
       61 gcaccgccag ccaccccggg ctgcgccggg tcgtcacccg gttcttcaac gcccggcgcg
      121 tggccgccgc cgtgccggtg atcgagcgtg tcgccgacga actgctcacc gcggcggccg
      181 agcggatcga cgccgtgggc gacggcgacc tgttcacgtc cttcgcgcag gtactgccgt
      241 gccgggtgct gatggagctg ctgggtatcg acgacgtccc cgcggccacg ctgatccgct
      301 ggagcgacgc ctcgctggaa ctgttctggg gccggcccac gccggaacgc cagctggaac
      361 tggcgccgct cgtcgccgag ttccaccagt ggctgacccg taccgtgcgg gacggcgccg
      421 ctcggcccgg ctccttcatc gcggccctcg gagagcaccg gctgcccgac ggggagcggc
      481 tcgacgtggc caccgcggtc ggggcctgct tcttcgtctt cgtcgccggg cagtccacga
      541 ccgggcagct catctcgacc gtgctgcgcc gcgcgctggc cgaggagggg ctgtgggcac
      601 gcctcgccgg cgaaccgggc ctcgccgagg cgtgggtcga ggaggtcctg cggcgcgaac
      661 cgccggtgac gacgtggcgc aggatcaccg cccgcccggt cgaactgggc ggggtgaccc
      721 tgccggaggg cgcgcaggtg ctgctgatgc tgatgggcag cggctccgat ccggaggtct
      781 tcaccgcacc ggaggagctg tgcccgcacc gggccgaggt ccgccatcat ctggccttcg
      841 gggtcggccg ccaccggtgc ccgggcgcct ccctggcgcg tacggaggcg gcggtggccc
      901 tgcgggccgc ggcgcgccgc ctgcccgggg tgcgtccggc ggagtcggcg gacgttccga
      961 tgctcggcct gctgtccttc cgggcgccgc tgcgggtcgc ggtgacacgg tcgtgacggc
     1021 cctcgcacgc ggcatactgg ccggcgtgcg agtggccatc atgacggcgg gatcacgggg
     1081 cgacgtggcg ccctacaccg gactcgggcg ggcgctgtcg cgggccgggc accaggtgac
     1141 gctggtgacc cacggggctt tcgaaccgct ggtggcggat tcggggctgg gattccacgc
     1201 gctgccggtg gatccgcggg cggagctgga gacttcgcgg gggcgggggc tgcaccgcag
     1261 cgcgagcggc gtcggcaagc tgctgcgggt ggtggggatg gcgcgggcgc tggtcgggcg
     1321 gatgaccgac gatctgctcg ccgcggcgcg gaccagcgag gtgctgctgc tgtccagttc
     1381 gctcgcgccg ctcgggcaca ccctcgccga ggggctgcgg ctgccgagca tgggtgtcta
     1441 tctgcaaccg ctggccgcca ccggggagtt cgcgccgccg gtactgggtg ccgggtcctg
     1501 gggcggtgtc gggaaccggc tcgccgggca cggggtgggc gcggccgtgg agcgggtgtt
     1561 ctcgggggca gtcccggcgg tacgggcccg gctggggctg ccggccctcg gtcccggcgc
     1621 ggcacggcgg gcccgggaga agcggaactg gccgatcctg cacggcttca gcccgctggt
     1681 cgtgccccgg ccgcgcgact ggcgggccgg actggaggtc accgggtact ggtggccgta
     1741 cgaccgtgac ctccgactcc cggccgggct gcgggacttc ctcgacgcgg gtccgccgcc
     1801 cgtgttcgtc ggtctgggca gcgcgaccgt gccggatccg gcggggctca gcgccgggat
     1861 cgtggccgcg ctgcggcgcg cggggctgcg cggggtgatc cagcggggct ggggcgggct
     1921 ggcggccgac ggggacgaca tgctgacggt cggggaggtg ccgcacgcgg cgctgttccc
     1981 caggatggcc gccgtggtcc atcacgccgg tgcgggcacc accgcggccg gggtgcgggc
     2041 cggggtgccc gccgtgcccg tgccggtgca gttcgacgcc gggttctggg cggcccggct
     2101 ggtggccctg ggcgtggcgc cccgcgcgct gccgctgcgc cgggtcaccg ccgacgccct
     2161 ggccgcggcc ctggtggagg cgacccgcga cgccgggtac cgggagcggg cgcgggcgct
     2221 cggctcccgg gtgcgggcgg aggacgggac cgcggcggtg gtggagcggg tgaaccggct
     2281 gcgcgggtag ggcacggccg ccggttcccg gcgttccggc gggccgttcg agcggcccac
     2341 tgggtcggtt ccggtccccc ggctccctca actcgccgtc ctgccggtga ggttgagcag
     2401 atactccttc cggttcagcg gattgtggtc cgtgcgcggc cgccggggta ccgcggcgcc
     2461 ccggtcgacg ggcgcgtagt ggtcgaaggc gctctccagc tcgccctcgc ccctggtgag
     2521 ccccggaagc cgctgctcca gcgcgtggac gagcgccgcc ggcaccacgc cgtcgaggac
     2581 gcacagcgcg ccgcgcgtct cggtggtgcg cggcaccgcc cgcagcgcgg acagcaccgg
     2641 cagcagagcg cccagcgtgt ccgccggcgc ctccagccgg aaccggtgca tcggttcgtg
     2701 cacccgggtg ccggcccggc gcagcgcctc ggccaggacc agcggggtca gcccccggaa
     2761 gtcggccccg gtgctggaca tgctcttgtc gaagccctgg tgggcgtggc tctggcgcgg
     2821 ccagtacccg gagtgggtca tggtgaccgt gcagtcgggg atccgccagc cgtacaggcc
     2881 ctgtcccaga gtctcccgca cggtgtcctc gacggccttg aagaaggcgt acggcatcga
     2941 gcccagctcc acctccagcc ggaactgcgt gcccgcgccg accggggcgg ggtcgacgcg
     3001 caggccgacg gtggcgatga aggggttgtc gtccttcttg atgaactcga ccgccgcacc
     3061 cgtcccggtc aggcgttcga cgcacagcgg tgtcgtctcg cggaaggcga cgtcgaggcc
     3121 gtagtcgtcg gcgagggtcg cctggacgac ctccttctgc acctccccgt acagcgacac
     3181 ggaggtctcc tggcgcacct cgtcgtgccg caggccgatc agcgggtcct gttcggccag
     3241 ctgggtgagc gcgaggtgca gggcccgccg gtccgccggg cggaccggtt cgacgacggt
     3301 ctccagggtc ggcggggcga agaggtgccc gtccgtggtg cggggcacgc cgagccagtc
     3361 gccgatcctg acctcgccga gaccccacaa ccgggcgatg cggcccgcgc cgaccgcgtc
     3421 ccggcggacg tccgtaccgt cctcgaagac gtgcacggcc gtcacccggc cctcgcggcc
     3481 ccgcgcaccg aagcggatcc ggtcgcgggt gcgcagggtg ccggagaaga gccgggcgta
     3541 cgccaccttc tcccccgccg gaccccgttc caccttgaag acggtgcccg agacgggccc
     3601 gtccgggtcg ccgccggcgg tgggcagcag ccgtccgatg ccgtcgatca gcgcgtccac
     3661 gcccgctccg gtgatcgcgg aacccgcgta cgcgggatgc accaggccct gccgggtctg
     3721 ctcggccagc gccgctcgca ccagggcgtc cgggacccgg ccgtcgacat aggcggcgag
     3781 caggtcgtcg tcgtggtcgg cgaggacgtc cagcgcggcc gggaccgggc ggggcgtgaa
     3841 gcgggccccg ggcgtgccga ggccggtggc ggtgcccatc gggacgacgg cggccgacag
     3901 ccgttcggcg gcggcgcgca gcacgtcctc gtaggccgcg ccacggcggt cgatcttgtt
     3961 gacgaagagc agggtgggaa tgcgcagccg gcgcagggtc cgcatcagca cccgtgtctg
     4021 cgcctggacg ccctcgacgg ccgagacgac caggacggcg ccgtccagca cgccgagcac
     4081 ccgctccacc tcggcgatga agtccgggtg gccgggggtg tcgatgaggt tgacggtcac
     4141 gccgtccagc gggaacgaga cgacggcgga cttgatggtg atgccgcgct gccgctccag
     4201 cgcgagggtg tcggtgcggg tgctgccggc gtcgacactg ccgatctcgt cgatgactcc
     4261 ggcgctgtgc agcagccgtt cggtcagact ggtcttaccg gcgtcgacat gggcgaggat
     4321 cccgaggttg agcaaatgca cgaagcgtca tgtccttggt ggtaggggcc gttccttgcg
     4381 ggatggacat ggacgcagcg cgcatggatc gctcctcggg gtgcgacgac gggtggtcgg
     4441 atgcagtgca gcagaaccgc gggcgaggcg ccaacggatt tacgacggga gcgggccgtg
     4501 cgggacattc ttccggtgct cagcggttgg tacgcggcgg ccgaaccgtt cggcctggcc
     4561 accgtcgtcg cggtcagcgg cagcgcgccc cgcgatcccg gcgcggcgat ggcggtcggg
     4621 ccgggcggcg aggccgtcgg cagtgtgtcc gggggctgtg tcgagggcgc cgtgttcgaa
     4681 ctggcgcggg aggtggcggc gagcggccgg gcgcggctgg agaagttcgg gtatggcgac
     4741 gaggacgcct tcgcggtcgg cctgacctgc ggcggcgaga tcaccgtgct ggtgcggccg
     4801 gtcagccccg gccacgaccc gtcgttcggc gcggtcgccg cgtccgtggc cgggggacgc
     4861 ccggtgaccg tggcgaccgt gaccgacggt ccggcgccgc gcggggccac gctggccgtc
     4921 tggcccggcg aggtgtccgg cacgctgggt acgagcggcc tggacgcggc ggtcaccgcc
     4981 gacgcgcgcg gcgaactcgc cctcggcgcc accggcgtac ggcactacgg gccgcgcggt
     5041 gagcggcggg cggacgaagt ctcggtgttc ctgcactcgt tcgcgccgcc gccgcggatg
     5101 ctggtgttcg gcgccatcga ctacgcggcg gccgtggcgc gcatcggtgt cttcctcggc
     5161 taccgggtca ccgtctgcga cgcccgcccg gtgttcgcca cgcccgagcg tttcccgccg
     5221 ggcgtggagg tggtcgtcga ctggccggac cgctggctgc gcggcaccgg gacggacgag
     5281 cgcacggtga tctgtgtgct gacgcacgat ccgaagttcg acgtgccgct gctggcggag
     5341 gcgctgcgcc ggcccgccgc gtacatcggg gcgatgggcg gccgccgcac ccacgacgag
     5401 cgggcgcgga agctggccgg ggccggggtc ggcgcggcgg aactggcccg cctgcgctcg
     5461 ccgatcggcc tggccctcgg ggcgcgcacg cccgaggagg tcgccgtgtc cgtcgcggcg
     5521 gagatcgtcg cgctgcgccg gggcggcagc gggactccgc tggccgcgac gacgggcgcg
     5581 gtgcacccgc cgcggccgta ggctcagcgg tcccggcgcg gtggcagccg gtgcagggtg
     5641 acgtcggtca gttcgccgtc ggcgaccgtc gccgtcatgt aggtgcagtg cggctgacgg
     5701 cggcggtcgg tgggcgagcc ggggttcagc agacgcaggc ccgacggggc ggtggtgtcc
     5761 caggggatgt ggctgtggcc gaagaccagc acgtcgaggt cggggaagcg ggcggcgcag
     5821 cgcgtctcgc ggccctgtgc gggtccggtc tcgtggacgg cgccgaagcg cagcccgccc
     5881 agttcggcgt gggccacctc ggggagccgg gcgcgcagtt cgggcccgtc gttgttgccg
     5941 tacacggcga ccagccggcg gctgtgccgc tccagcaggt cgagggtggc cgtgtcgacc
     6001 cagtcccccg cgtggaagac gacgtcggcg cgtggcagtt cggcgagcag cggcgcgggc
     6061 agctcccggg cgcgcttggg gacgtgggtg tcggacatca gcaacaggcg caccgcctca
     6121 gcgtacggcc gccggtcagt cctcacccct cacgatgttc ccctccaggg cgaggtccgg
     6181 gcgcgctggg ccctcggggt cccggacggc cgacacgcag gtgcgcaggg ctggtttctc
     6241 cttcatgcgc cgggccctcg accagcctgt ctcgggcctt cgggcgacgg gtttgtcact
     6301 ggtgggtgtc gtcacggcct gctcctctca cttcactgac gccaccccgg gtccccattc
     6361 gttgaagtgg gcaaacaccg gtcgggtcag gtggcgccgg acccgccccc gccgaaggag
     6421 ccgctggagc cctcgtccca gcgcgggcgg cgctggtcgc cgctgggggt gcccccggtg
     6481 ggcctcagtt cgtgcggggt gagccgttcg ccctcgccca tgccgtgcgg ggcccgctgc
     6541 tcccgggtct cgtggaccgg cccggagtcg ggcagcctgg gctgttcgtc ggggcggggc
     6601 cggcggggct cccgcttgcg cgcccggata ccgagcagta cggcccagat cagtgcggcg
     6661 gtgatgacga cgcctccgac gaggatgacg gccatgccga ccccggagcc cgaggcggcg
     6721 acttcgctgg cggttgtgtt catggacgtc gagtacccga agtcgccggg tgaatgacca
     6781 gtcacccccg gacgggtgcc ggtgtgcgac cggcgggccg gtcccggcct gaccgcggcc
     6841 gatcgggcgg ccctggccgg gccgccctcc gcggtgtgcg gtccctaggt gttcggccgg
     6901 gccacgctga tgtcgccgag ggccgagccc gggtcgcgtt ccatcgccag gtcgcccagg
     6961 gagacgatgc ccaccgggtg gccctgctcg acgacgggca cgcggcgcac ggcgtgttcg
     7021 cgcatcagct ggatggcgtt gtccaggtcc tcgtcgggct ggagcgtgaa caggtcctcg
     7081 ctgcacgcgc cggccaccgt ggtctgttcg gggtcgccgc cctcggagat cgaccggacg
     7141 accaggtcgc ggtcggtgac caggccccgc aggtcgtcgc cctcggtgac caggaccgcg
     7201 ccgatgtcct cgtcgcgcat gatccgggcg accgccgcga ccgacgtctg cggttccacg
     7261 gtcaccggat cggcggtcat gatgtcgcgg acgtgctgag tcatgacgta cctcctcgtc
     7321 gtcgtccgtc cgcgctccgg gtacccggtc tcagggctcc agcacgagct cgctccacac
     7381 ctgcttgccg ccgctgacgg ggacggtgcc ccaggccgcc gacatggcct cgacgaggag
     7441 caggccgcgg ccgccggtgg cctcccagcc gatgctggtc ggcttgaccg gggtgcgggg
     7501 cgaggcgtct gcgacggcga tccgcatccg gttgccgacc agcgtgaggt ccatgcggac
     7561 cgggccctcg gtgtgcacga gggcgttggt gacgagttcg gagacgatca ggaggaccgc
     7621 gtcggcgtgg gcggcgacgc cccaggcgcg cagggtgcgc ttggtgaagc ggcgggcgtg
     7681 ccgcacggcc tccgggaccc gccagaccga ccaggtctcc cggcgcgggc ggaccgccat
     7741 gccgtcgtag cgcatcagca gcagggcgac gtcgtcgctg cgccgggcgt tgcccagcag
     7801 gccgtcggcg accagcccga ggtgggcggg gtcggagcgg gcgagccgct gggcgaagcg
     7861 gtccatgccc tcgtcgatgt cggtgtcggc ggactccacg agcccgtcgg tggtgagggc
     7921 gagcaaggtg ccgggctgga gccggatcgg ggtcatggga aagtcggctt gggtgagcac
     7981 gccgagcggc gggccgccct ccgtctcgac gacctgggcg gagccgtccg ggtggcgcag
     8041 caccgggtgc agatggccgg cgcggacgca ccaggcggtg ccctcctcca tgtcgacgtc
     8101 gacgtaggcg caggtggcga agaggtcggt ctccatgtcg acgaggagcc ggttggcgtg
     8161 cgagacgacc acgtccggcg ggtgtccctc gacggcgtag gcgcgcagcg cggtgcgcat
     8221 ctggcccatc agggtggcgg cggccgggct gtggccctgc acgtcgccga tgacgagggc
     8281 gacgtggtga tcgggcagcg ggatgacgtc gtaccagtcg ccgccgacct ccagtccggc
     8341 ggtggcgggc aggtagcggg cgacggcctc ggcgccgggc agtctgggga gccggcgggg
     8401 cagcagctgg cgctggagca tgccgacgag ttcgtgttcg gcgtcgaagg cgtgggcgcg
     8461 catcagggcc tgtccggcga gtcctgcgga ggcggtgagc agggcgcgtt cgtcggggcc
     8521 gaagtcgtgc gggctgtccc agccgatcag gcaggcgccg gccatccggc cgccggcgga
     8581 cagcggcagt acggcgagac cgccggggcc gacgtcggcg agggcgggtt ccagggtggt
     8641 gccggagggc cagatctggg cgcggccctc gcgcagcgcg gcggcgaggg tgggcatggc
     8701 ccgcacgggc gcgtcgggcc actcggtgcg ccactccagg cgccacagtt cgggccaggc
     8761 ctcgggttcg ggcgggtcga ggacggtgac gacgagccgg tcgtgctcca gttcggcgag
     8821 ggcgatgcgg tcggcgcgca gcggccggcg cagggcggcg acgacggcct ggctgacgtc
     8881 acggaccgtc ccggcggtgg agagcgcggc ggccaggcgt tgcacgcggg cgacgtcggt
     8941 gacgtcggag cgcagctggg aggcgtcgac gacggtgccg acgagccgcg cctgctgtcc
     9001 ctcgccgccg ggctgcatac ggccgcgcag ccgcagccag cggggcgggc cggccgggcg
     9061 gcgcacgcgg aactccagtt cgcggtcgcc cacggacatg tggtcggcct cgaccacgga
     9121 catcagcgag ggcaggtcct cggggacggt gagcccgagc agggtctcga ccttgccgtc
     9181 gaagtcgtcg cgggtgaggc cgaacaggtc gaggatgccg tcgccgacct cgacgcggcc
     9241 ggtgtccatg gcgagggcga aggcgtgcgg cgggagttcg ccgccctcgg gatgggcggg
     9301 cggggcgggg caggtgacgg cgtcggcgat cagttcgagg gccttgcgct gatcggtgtc
     9361 gaagccgtgc gggtcctcgc tgacggcgag caggcagccg ccgtgggtgt cccggctcgc
     9421 gggcagcgcg gccaggtgga actccggtcc cggggtgcgc cggctgtcgg cgcgggcggc
     9481 cagctcggcg gggctcaccc agaccggccg ccggtcgcgg tgggcgtcgg cggccgggga
     9541 gcgcccggcg accggataac tgtcgcgcag cccgtacagc gtccggggga cgcccgccga
     9601 ctcgaccagg cacagcaggt ctccgtcctc gtcgggggcg tacacggcgg cgaaagtcgc
     9661 ccccgcgaag acgagtgact gttcgaggac gcggtgcagc cgttcggggg tgtcccggtc
     9721 gtccgtgatc gctcgcaggg cgatctcggc gcgcggcgtc accgttccac gtcccgcggc
     9781 gccgtcattg accacgtccg tattacagcg ctaatggggc gtccgcgcag cccctgtgtg
     9841 cgttccgtgg agccggcgcg gagtctgcgc gcagtccgcg gtcgaaaggt cccgaacatg
     9901 tcttgacccg tgcgtaccgc acaccgacct cgtgacaggc gtgactgtcc ggagccgccg
     9961 gccggctgga aggctcagtg gccgtcacgg agggggaggc atggacaagc ggtacgaggt
    10021 gtacgccctc gcggacgggc acttctacga cacgcccgac cggctcacgg gcgacgggca
    10081 caccgccgct ccgctgtacg cggtggcccg gcgcgaggtg cccgagggct ggcgtgcggc
    10141 gcgcaccggc gactggctga cgatgacgcc gctcgacgcg gacggcgagc cgctgcccgg
    10201 tccggcgcag ggctggaaga tccacgcctc ggccacccgg gcgaacgcgg agcggatcgc
    10261 ggagatcgtg tgggactact gcgtgccgcg ccgcatcccg ttcaagttcg tcccggccgc
    10321 gcatctgctg catctgcgca acgccaagta cgcgccacgc gagggcagcg gcaagttcgt
    10381 caccgtctac ccggtcgacg aggagcagct gcgcctggtg ctgaccgagc tgggcgcgct
    10441 gctgaagggc ttcgaggggc cgtacatcct gaccgatctg cgctgggacg acggtccgct
    10501 gcacgtccgc tacggcgcct tcgcgcggtc ctacgtggtc gacgagcgcg ggtcgctggt
    10561 gccggcggtg cgcgacggcg agggacggct ggtgccggac cggcgggacc cgtccttccg
    10621 ggtgccggag tgggtgacgc tgccggactt cctggccccg cagctggcgg cgcgcaacgc
    10681 gacgacggtc ggcgacctgc cgtaccgcat cgagaaggcg ctgcacttct ccaacggcgg
    10741 cggcgtgtac gcgggcaccg acacccgtga cgggcgccgg gtcgtgctga aggaggggcg
    10801 gccgcacgcg gggctcgcgg ccgacggggc ggacgcgatc gcccggctgg agcgggagaa
    10861 gcgggccctg gagcaagtgg ccggcaccgg ggtggtgccg gaggtgcgcg actggttcac
    10921 gctgggcgag caccggttcc tggtgatgga cttcgtcgag gggcggccgc tcaactcgtt
    10981 cttcgccgaa cggcacccgc tgctcgtccc cgaccccgat ccgcgggccg tcgccgacta
    11041 cacggcgtgg gcgctgcgca tccaccgggc ggtggagcgg gcggtggacg cggtgcacga
    11101 gcgcgggatc gtcttccacg acctgcacgt cttcaacatc atggtggcgc ccgacgagga
    11161 gtcggtgttc ctgctggact tcgaggcggc cgcgccggtg gccgagaacg gccgccaggt
    11221 cgtcgcccac ccggggttct tcgcgccgcc cgaccgccgg ggcgccgacg tcgaccgcta
    11281 tgcgctggcg tgtctgcggc tcgccctgtt catgccggtg accacgctgt tcgtgatcga
    11341 ccggggcaag gcggcgcatc tggccgaggt gatcgccgag cagttcccgg acgtgccgcg
    11401 ggcgttcctg gacgaggcgg tcgcggagat cacccgggac gcggccgggc ccgcccgcgg
    11461 cgggtcggcg cggctcgtcg aacccgccga ctggccgcac agccgggact ccatggtcaa
    11521 ggcgatcctc gcctcggcca cccccgagcg caccgaccgg ctcttccccg gcgacatcgc
    11581 gcagttctcc gacggcggcg ggctcggtct cgcgcacggc gcggccgggg tgctgcacgc
    11641 gctggccgaa accggcgcgc agcgctacga ggagggcgaa cgctggctcc tcgaccgtac
    11701 ggccccgccc ccggcgggca ccccgctggg cctgtacgac ggtctcgcgg gcgtcgcgct
    11761 ggtcctggac cggctcgggc accggcagcg ggcgctggac ctggtcgacg gcatcctgcg
    11821 cgagcgctgg cagaacctct cctccgacct gcacggcggg ctcgcggggc tcggcctggt
    11881 cctcgggcac ctcgccggca ccaccggcga gccgggcctg cgggagcggg ccgacgaggc
    11941 cgcggagatc gtcgtacgac ggctcgcgga gccgcttccg gaggcgcccc ggcggcgcgc
    12001 cgggctgctg cgcggggcga ccgggcaggc gctgttcctg ctgcggcgcc acgaggccac
    12061 cggcgacggt gagctgctgg cggcggccgg gcgggcgctg cggcgggatc tggcctcctg
    12121 cgtggtccgc gagggcgggg cgctggaggt ggacgagggc tggcgcaccc tgccgtatct
    12181 cggtgacggc agcgtcgggc tcggcatggt gatcgacgac tacctcgccc acgccacgga
    12241 cgacaccggg gagctcgaac gggcccgcgc gggggtgctc accgccgcca cctgccgctt
    12301 ctacgcgcag cccgggctct tccagggccg ggccgggatg atcctgcacc tcggccgcac
    12361 caccgcgccg ggtgccgatg tccgggcgcg gctggcggag cagctcgcgg ggctcggctg
    12421 gctcgcgatg ccgtaccagg gccagctggc cttccccggc caccagatga tgcggctctc
    12481 catggacctg gccaccggaa cggccggctg cctgctggcg ctgggcgccg ccctcggcga
    12541 cacgcccgcc gcgctgccgt tcctcccgcc gcccgccggg cggccctcat gacgcggcgt
    12601 cgccgaccgg cggcgtcgtg acccaacccg tccccacggg acgtctcacc atcacggaaa
    12661 ggaaaagaag atggcccttc tcgacctgca gacgatggaa gccgacgagc acaccggcgg
    12721 cggcggcgcg agcacggtga gcctgctctc ctgcatcagc gcggcgagcg tgctgctctg
    12781 tctctgaccg gcaccgcacc accagggccc cgggcggcag cgtccggggc cctgcccgtg
    12841 ccccgggccg gcaccggcta cagccagccc tccccctgcg agatgcggat cgcgtctatc
    12901 cggttgcggg cgccggtctt gcgggtgatg gcggccatgt agttgcggac ggtgccccgg
    12961 gacaggtgca ggctgccggc gatctccgcg atggacgcgc cctcggccgc cagcgacagc
    13021 acgctgagct cccgtctggt cagcggtatc tgggaggcct tgaggaagcc caggcccagc
    13081 gtgttgtcga cgaaacgttc ccctgcggcg acgcaccgga tgccccgcac caggcgctcc
    13141 ggcgagcccg ccttgtcgac gtagccgagc gcccccgcct ccacggcacg ccgcagcagc
    13201 cccggccggt ccgcggtggc cagcaccagc agccggggcg gtctctcgcc gccccggccg
    13261 cacagctcgc ccagcggcgg gatgccgtag cggcctgtgt agtccaggtc cgcggcacac
    13321 acgtccggcc gtaaggatcg cgcccggccc ggcgcggctt gccatggggc gtcgtcgacg
    13381 cccaggtcgg gttcccggct cagccactcc gccagaaccg atcgcaccag actcgaatca
    13441 tgcaccagaa gtacccggat caccgctgtc cctttcagct ctccgccgtc ggctcgtcgt
    13501 ggtgagcgcg tgcccattct tggtcccggc gctcctgcct gagcgcgcaa gatccggcca
    13561 acgggatgcg cgggggcgcg tacagcgcgc ccatgctcct tcccacgcat ccgttcgggg
    13621 ggcatgatca ccgggcttcg gggtacgcga ggcgcccttc gtcgcggccg gcgcgtccgc
    13681 ccagagatgg cgcggacggc cggggcgaga gagatttgat gccggggaca cggctcgcgg
    13741 cgccgcgagg aggtggtcgg cgtggacgac gggcagccgc acacccgggc accggcggcc
    13801 gagcggcagc cggccggcga gcccctgctg tcgctcgcgc tcgccgcgat gctcgacggc
    13861 gtgcacgccc actccggcgc ggtgtacctc ctctcccccg acggacaagt gctcgagatg
    13921 gcggtgatgg ccgggctgcc gcgggccttc tccgcgccct gggagcgcgt cggcgtgggc
    13981 gcgccgatcc cggtcgccga agcggtgcgc gaacggcggc tggtctgggt cggcggcgag
    14041 gaggagatgg cccgccgcta ccccagggtc gccgtggtcc tgccgtaccc cttcgcgctg
    14101 gccgcggtgc cggtggtgac gggaggcacg gtgtacggcg cggtgttcgt cacctggccc
    14161 ggctcccacg cgccggcgct gaccgaccgg atccgggagc agctgacgtc ggcctgcgac
    14221 cggctggcgc tgcggctgga gcgggcggcc cgggagagcc gcccggtgct gcccgagccg
    14281 gatctgctgg ccgcgccggt ggtcgggggc acaccgggca cgatcggcgc ggtcgaggcg
    14341 gcccggatgg tgtcccggct tccgtacggg ctgtgctcgc tcgacatcca cgggcgggtc
    14401 gccttcgcca acccggcggc ggccgaactg atcggtgagc cggtgtcccg gctggtgggc
    14461 acccagctgt gggcgtccgt accgtggctg aacgacccgg tctacgagga ccggtaccgg
    14521 gccgccctgt tcagccagca cgccacgtcg ttcgtggcgc tgcgcccgcc cggcgagtgg
    14581 ctgtccttcc ggctgtaccc gagcacgagc gggctcagtg tgcggatcac ccgggcccgg
    14641 tccgtctcgc cgacggggca ggccgagccg tcggccggtg aggggccgtc ccggctggtc
    14701 accatctcgc aggtgctgac gctggcgagc gcgctgaccg aggcggtcgg cgtgcaggac
    14761 gtcgtccagc tggtggcgga cgagctcgcc ccggccgtcg gcagccacgc cctggtcctg
    14821 ctggcctcgc ggggcgggcg gctgcgggtg ctggggcatc gcggctatcc cgatccgcgg
    14881 ctcgtggagc ggttcgacgg gacgccgctg gggtcggcga cgccgggggc gcacgccctg
    14941 cacaccggcg tgcccgcgtt cttcgagtcc cgggaggagc tggagcggct gtatccggcg
    15001 cgggcggaga gcccggacgg gttcgcggcc tgggcgtacc tgccgttgat cgcctccggg
    15061 cgcccggtgg gcacctgtgt gctcgcctac tccggtccgc gccacttcgc ggcggacgag
    15121 cggtcggtgc tgaccagcat ggccgggctg atcgcgctgg ccctggagcg ggccctgctg
    15181 tacgacgcca agcaccagct ggcgcacggc ctccaggcgg cgctgctgcc gccgtccctg
    15241 ccgccgctgc cgggcatcga cgcggccgcc cgctatctgc cgagcacacg gggcatggac
    15301 atcggtggcg acttctacga cgcggtgcct tcggcgggca ccgcggtcgc ggtgatcggc
    15361 gacgtgcagg ggcacaacgt gacggcggcc gggctgatgg ggcagatccg gaccgcggta
    15421 cgggcgtaca ccgccgtcgg ccagtcaccg caggaggtca tgggcagcac caaccggctg
    15481 ctgatcgacc tcggcaccga tctgttcgcc agctgcctgt atctgcggct gaacccgcgg
    15541 cacgcgcggg cggtgatggc gcgggccggg catccgccgc cgctgctgcg ccggccggac
    15601 gggcgggtcc gggtgctcga cctggcgggc gggccgctgc tgggcatcga cgcgtcggcc
    15661 gtgtatccga cgacggaggt cgacttcgcg cccgggtcgg tgctcgtgct gtacaccgac
    15721 gggctgatcg agtcccccgg cgtcgacatc gaggaggcgc tggccgcact gggcgagctg
    15781 ctgacggagg cggggcggct gccgctggac gagctggccg acgtactggt cgggcagggg
    15841 gcgggcgcgg cggagcgggc ggacgacgtg gcgttgctgc tgctgcgggc gcgggggtga
    15901 ggcgggccgg tacgacgaag gtccggcccc tccgccgagg ggccggacca cgtggtgggg
    15961 cgggtcagct gtgattctgg gtcaggccgg agtcgccggc ctcctcggcg gcctcgtctc
    16021 cgccgccggc ctgctcaccg gcgcccgctt gctcgccgcc gacgccctcc tgtgcgtcac
    16081 cggcgccctc ctcggcaccg ccgacgccct cttcggcacc gccgacgcct tcctccgcgc
    16141 ctccgacgcc ctcctgcgcg ccaccggcac cttcctccgc gccaccggcg ccttcctgct
    16201 caccgccggc gcccgcgcct tcgtccgcgc ccgcgccgcc ggcgccgtca gcgccctcca
    16261 gcgtcgcgcc gaccgcctcc agtgccgtgg tgaccggctg gaagaacgtc tccccgccga
    16321 ccgtgcagtc gccgctgccg ccggaggtca ggccgagggc gaggccgtcc tgggtgaaca
    16381 tcgagccgcc gctgtcgccg ggttcggcgc acacgttcgt ctggatgagg ccggtgaccg
    16441 tgccctcggg gtagttgacg gtggcgtcga gcccggtgac ggtgccgtcg gcgaggcccg
    16501 tggtggagcc catccggaac acctcctggc cgacggtggc ctccgccgcc tggaggatcg
    16561 ggacggtctg gccctcggcg ttcacctcgc tcggcgcctg ggtggcgggg tcgtcgtact
    16621 tgacgagggc gaagtcaccc tcgccgggga acaccgcctg gtcgacggtg ccgatcggcg
    16681 ccccgccctc ggcgtcggac cactgctgcg ccgcgacgcc gcagtgaccg gccgtcagga
    16741 aggcgggggt gccgtcgccg gcggtgacgt tgaagccgag cgagcagcgg gcgccgccgc
    16801 cgaagatggc gtcgccgccg gaggcgaagg tcttgaaggt gccgttggac ttccgcaggg
    16861 tcgccatgcc ggaaccgagg ctctgcacgg tggactccag cgtgtcccac ttggcgccgg
    16921 tgacggtgct gtcggcggtg acgaggacct tgttcgttct ggggtcgacg gcccaggcgg
    16981 tgccggggat ggtcgcctcg ctcttcaggg tctgcgcggc cgccttcagt tcggcggcgc
    17041 tgttctcgac ctgccggacc gccgcgcccg ccttcttggc ctggacgacg agctggttgt
    17101 cgtcgccgac cacgttgacg acgagctgct ggcggtcggc gtcgtagtag gacccggcga
    17161 acgcgtcgcc gagcagcccg gcgagctggt ccgcgagatc cgaggcgtcc gcggacttca
    17221 gggtcctggg ggcggacttg gcttccggcg cgccgtcctg ggacgcgttg gcgttcggca
    17281 gcaggatggc cgccgctccg agcgccgcca cgccgcctgc ggccagcacg gccttgcgct
    17341 tcggaattcg cttgtgactc aagacttctc gacctcctga gggaccgggg tccggccgcc
    17401 ctgtcggcgg ctgtcggggg tgggcgcctg gatggccact ggtacgcagg gcgcgctcgg
    17461 ggcgttcaat cgggtgtgcg aaaccggagg gaccgggatg tgtgccgacg ggacggcggt
    17521 gggggccgcg gtggggattc cgccgtggtt cggggaaatg tctccccatg acgatgacca
    17581 cggcggaagc cgagaagatc ctctccgtga acttcgcccc ctgggtcctg gaactgggcc
    17641 tgaccgtgga ggcgttgggc gacgaccggg cgacgctgcg gctgccctgg tccggccggc
    17701 tggcccggga gggcggcgcg ctgtcgggtc aggcgctgat ggccgccgcc gacaccgcga
    17761 cggtgatcgc cgtctcggcg gcgcggggcg cgttcgtgcc gatgacgacg gttcagcagt
    17821 cgacgtcctt ccagcgcccg gtggcggagg cggacgtgct gatcaccgcg gtgctgacca
    17881 agctgggccg ccggatggcg ttcgcggaca tcgcgatgac ggtggagccg ggcggggacc
    17941 tcgcggcccg ggcgagcacg gtctacgcga tcctgggctg acacgttccg cgaccggtcg
    18001 gtgacggtcg gttccggtca cggacgggaa cgagagcttc agggaatctg cacatcgaat
    18061 gcccaacggg ctcaccgcga gcggcggatc cgcacatgcc cgaggcggcg gccacgcctt
    18121 tgggaccgga gtgccggatt cgccgatccg gcggcaagag ccgggatgcg ccgatgccgt
    18181 gcggcatgtg aagaagtcgc cgacaagccg tgcgcgcacc tgcacggttg ggcacgcgga
    18241 gggctcaaaa ccccaggtga ggcgggtggt tgattggagg acggaggtcg cagcgtgctt
    18301 tgatccttcg caccgcgggg gccgcgaacg gcgcctctac ggggcgcctg gcgcctgcgg
    18361 tcgcggccgt ccgtctgtcc ccagaggggg ccgctccccc cttgtgaaat atccatatga
    18421 agggaagttc catcatgaac tccacccccc aggttgagac cgtcgagatc tccgacgccg
    18481 agctcgacaa cgtcgccggc ggtctgcacg tgaacgccct gggcaccgtg accggcctgg
    18541 tggacggcgt cgccccggtt tccggcctgg tcgacacggt cgtcggcacc gtcgagggtg
    18601 tcaccggcct gaacaccgcc ccggtcacca acctggtcgc cggtctctga tcgcaccccc
    18661 ggggtgcccc gccgagtccc ggagccgtat cccggctccg gggctcttcg gatgtccgtc
    18721 acgcaattcc acccggtgag ggatcagttc cgtgcagttc cgccaacagg ccctcgccag
    18781 gctccagtcg ccggaggagc tggaccttcc ggtgcgcctc gcccgtccgc agggctggct
    18841 cgtgctgtcc gtgacagtgg tcgcgatggc ggccgcctcg gtgtgggcgg tgacgggcag
    18901 cgtctcctcc acggtgagcg cgcccgcgat cctcacccac gggcagggca gttacgtcct
    18961 gcagagcccc gtcgccggcc aggtcaccga gatcctggcg aaggagggcg agcggctgcc
    19021 cgccgacgcc cccgtactga agatacgtac cgccgagggc gagaccgtgg tccgcaccct
    19081 cgccgcgggc cggctgaccg cgctcgccgc gacgatcggt cagatcctcg ccaccggtgc
    19141 gaacgtggcc gccgtggaga aggtcgccgc gagggacgcg ccgctgtacg cgacggtgta
    19201 cgtccccgcc gagaacgcct ccgccattcc cgccgacgcg cccgtggacc tcaccgtgca
    19261 gacggtgccc acccaggagt acggcgtgct gcgcggccat gtgaagtccg tggaccgctc
    19321 gccccagacc gcccagcgga tcgccgcgtt cctcggtgac agccagctcg gcgagcagtt
    19381 caccaaggac ggccggccgg tcgcggtcct ggtgcggctc gaccggtccg cgtcgacgga
    19441 gagcggttac gcctggtcga cgacggacgg cccgccgcac gccctcacct ccatgaccgt
    19501 ggccaccggc tcgatccggc tggccgatca gcgtcccgtc gattggctgc tgccgtgacc
    19561 accaccgccg aggaaacccg gggccggcgc cgggccgccc cgccgcggcg cacggtcccg
    19621 gggacccgcc gccggaccgt ccgcaccccc accgtgctcc agatggaggc cgtcgagtgc
    19681 ggcgccgcct ccctggcgat ggtgctcggc cactacggca agcacgtccc gctggaggag
    19741 ctgcgcatcg cctgcggtgt ctcccgtgac ggctcccgcg ccagcaatct gctgaaggcc
    19801 gcccgcggct acggcctgac cgccaagggc atgcagatgg acctggccgc gctcgccgag
    19861 gtgcgggcgc cggccgtgct gttctgggag ttcaaccact acgtcgtcta cgacggcatg
    19921 ggccgccgct tcggccgccg cggcgtctgg gtcaacgacc ccggcaaggg ccgccgtttc
    19981 gtgtcgacgg aggacttcga cggcagcttc accggtgtgg tgctggtgat ggagcccggc
    20041 gaggacttca ccaggggcgg gcgcaggccg ggcgtcctcg gcgccatgcc ggcccggctg
    20101 cgcggcaccg ccggcacgct gcccgccgcg gtgctggcga gcctgctgct ggtcctggtc
    20161 ggcgcggcgc tgccggcgct gagccggacg tacatcgaca tgttcctgat cggcgggcag
    20221 acctcgctgc tggacgtgct gttcgcgtcc atgggcgcgt gtgtgctgct cacgctggtc
    20281 ctgacctggc tgcagcaggc gaacctgcat cacggccgga tcatctcctc gacgctgtcc
    20341 agcgcccgct tcctgcgcca tctgctgcgg ctgccggtca ccttcttctc ccagcgcagc
    20401 ccggccgacc tggtgcagcg gctgcagtcg aacgacgcgg tcgccgagac gctggcccgt
    20461 gacctggcgg cggcgggcgt ggacgcggtg gtcgtggtgc tctacgccgt gctgctctac
    20521 acgtacgatc cgcagctgac gttcgtcggc gtcggggtgg cgttgctgaa catcgtcgcc
    20581 atgcgggtgg tgatccggct gcgcgcgacc cgtaccgcga agctgcgcgc cgacaacgcg
    20641 cggctgacga ccacggcgta cagcggtctc cagctgatcg agacgatgaa ggcgaccggc
    20701 ggcgaggacg ggtacttccg caagtgggcc gggcagcacg cgaccacgct ggaggagcag
    20761 cagcggctcg gcgtgccgag cgcctggctg ggtgtggtgg cgccgacgct cgccacgctg
    20821 aacagcgcgc tgatcctgtg gatcggcggc atgcgggcca tcgaggggca catctcggtg
    20881 ggtctgctgg tcgccttcca ggcgctggtg acccggttca ccgccccgct gacccggctg
    20941 aacggggtcg cgggccgcat ccaggacttc gcggcggacg tggcgcggct gaaggacgtg
    21001 gagaacttcc gcgcggaccc gctgtactcc cgcgcgggcg gcgagtcgac ccggcggctg
    21061 cacgggcacg tggagctgga gaacatcacc ttcggctaca gcccgctcga caagccgctg
    21121 ctgaccggct tcgacctgac ggtcggtccg gggcagcagg tggcgctggt cggcggttcc
    21181 ggcagcggca agtcgaccgt gtcccggctg atcgccggtc tgtacacacc gtgggagggc
    21241 gtcatccgca tcgacgggca gcgcctggag gacatcccgc gcggcgcgct cgcggcgtcc
    21301 gtctccttcg tcgaccagga cgtgttcctg ttcgagggca cggtccgcga caacgtggcg
    21361 ctgtgggatc cgtcgatccc ggacgacgcg gtcgtggagg cgctgcggga cgcggccctg
    21421 tacgacgtgg tgatgcgccg tccgggcggc atccacagcc gggtcgagca ggacgggcgg
    21481 aacttctccg gcgggcagcg ccagcgcctg gagatcgccc ggtcgctggt gcgccgcccc
    21541 agcatcctgg tgctcgacga ggtgaccagc gcgctcgacg ccgagacgga gctggtcgtg
    21601 atggacaacc tgcggcggcg cggctgtgcc tgtgtggtca tcgcccaccg gctgagcacc
    21661 gtgcgggaca gcgacgagat cgtggtcctc cagcacggca cggtcgtcga acgcgggcgg
    21721 cacgaggagc tggtggcgcg cggcggcgcg tacgcggcgc tggtcaggga gcggtgagat
    21781 gacgacggtc gacgagggcg acctggtcct gggcgccctg ggcgcgctgg gcacgccgat
    21841 cgacggcacc gccctgaccc ggctcgacct ggaggggccg caggtgctgt ggctggtggc
    21901 gtccggtgcg ctggacctgt tcgcggtgga cgcgggcggg cagggccact ggcaccatct
    21961 gggccgcctg gaggcgggca cgctgctgct cggcccggtc gccggcccgc agcacacgct
    22021 ggtggcgcgt ccggtgcggg actgcgtggt gcgccgcgtc ggcctgcgcg agctgtacca
    22081 gccggcggcc acgcagacgt ggtcgtacga cgagtacggc aacccgcagt acgtgccgcc
    22141 gacgacgagc ccgctggagt acgcgctcgc gctgggcgtc ggccgtggtc tgtcggtgct
    22201 cttccaggcg ccgatggcgg ccgagggggc gtcggcggtc accgacgagg acgtcttctg
    22261 gatgcaggtg ccgccgggca gcgtgcagta cggctccctg tacggcgcgg aggccgccgc
    22321 cgacctgctg atggacccgg cggtgtggca gagcatggtc gaccagcagt accgcctgct
    22381 gaccacgctg gaccgctgga tcgagcagct ggagcgcacc cacgagaccc gcaccgcggc
    22441 cggtatcaag gccggtgagc aggtgcgcgc gcaggccgac cggacgctgc tggcgtccat
    22501 cggccgctcg tcggcgcggc gcaccacgtc cgccgacgcg gacgccacgt acgcggtctg
    22561 ccggctggtg gcccgcgcgg ccgggatcac gctcgccgac cccgggcacg gcggcaccga
    22621 gagcgaccgc ctcgacccgg tggagcgcat cgcgctcgcc tcccgggtgc gtacccgggc
    22681 ggtgcggctg gacgggagct ggtggcggga cgacgtcggt ccgctggtcg ggcagcgggc
    22741 gctgtccggg gcgcccgtcg cgctgctgtg gcggcgcggc ggctatgtgg ccgtccatcc
    22801 ggcgaccggg cgggagacgc cggtcgagaa ggccaacgcg gccgagttcg agccgcgcgc
    22861 ggtgatgttc taccggccgc tgccggaccg cccgctgggc ccgctcggtc tgctgcggtt
    22921 ctgtatgcgg ggcacgcgcg gcgacatgac cgggctgctg ctcagcgggc tggtgacggt
    22981 ggcgatcggc gcgctggtgc cgatcgcgac cggcaaggtg ctcggcgagt acgtgccgaa
    23041 ggcgcaggcc gggctgatcg cgcaggtctg tgtcgcggtc gtcgtcggca gcgtggtcgc
    23101 ggcggcattc atgctgctgc agaacctgac catcctgcgc ctggagggcc gtatcgaggc
    23161 gacgctgcag ccggccgtgt gggacaggct gctgcggctg ccgacgaagt tcttcaccgg
    23221 ccggtccacc ggcgagctgg ccagtgcggc gatgggcatc agcgcgatcc gccgcctgct
    23281 cgcgggcgtc gggccgacgg tcgcccagtc ggtgacgatc ggcgccgtga acctggggct
    23341 gctgctctgg tacagcgtgc cgatggcgct ggcggcgctc ggcatgctcg tcgtcatcgc
    23401 cgccgtgttc ctcgggctcg ggctgtggca ggtgcgctgg cagcggcggc tgacggtgct
    23461 cacgaacaag ctgaacaacc aggccttcca gaccctgcgc ggcctgccga agctgcgggt
    23521 cgcggccgcc gagaactacg cgtacgccgc ctgggcgggc gagttcgcgc gcagccggga
    23581 gctgcagcag cggctgggcc ggatcaagaa cctctccgcg gtgctcggcg cggtgtatct
    23641 gccgctgtgc
//
