LOCUS       NZ_LIVZ01000002        29821 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0107 scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_LIVZ01000002
VERSION     NZ_LIVZ01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0107
  ORGANISM  Streptomyces sp. TSRI0107
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 817466)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817466)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905845.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,745
            CDSs (total)                      :: 7,667
            Genes (coding)                    :: 7,467
            CDSs (with protein)               :: 7,467
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 200
            CDSs (without protein)            :: 200
            Pseudo Genes (ambiguous residues) :: 0 of 200
            Pseudo Genes (frameshifted)       :: 85 of 200
            Pseudo Genes (incomplete)         :: 158 of 200
            Pseudo Genes (internal stop)      :: 13 of 200
            Pseudo Genes (multiple problems)  :: 51 of 200
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:19:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 29821
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVZ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29821
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29821
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29821
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[12661:15821]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12662..15821
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(50..676)
                     /locus_tag="AMK31_RS04195"
                     /old_locus_tag="AMK31_04115"
     CDS             complement(50..676)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656837.1"
                     /locus_tag="AMK31_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04115"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_073939000.1"
                     /transl_table=11
                     /translation="MGKLVSTVFVTLDGVYQAPGGPQEDTRDGFEQGGWVFPYVDDDFG
                     RFVDDVFGRVGAFLLGRRTYDIFAAYWPKVTDPDDPVAGPLNRLPKYVPSSTLTDPGWS
                     GTTVLRGDLAEEVGALKERTDGELQLHGSGALARSLLDLGLVDTLHLLTFPVVLGAGRR
                     FFTEGTVPTAFRRTAGSVTGAGVSIQSYEVAGRPEYGTVGDSENG"
     gene            875..1618
                     /locus_tag="AMK31_RS04200"
                     /old_locus_tag="AMK31_04120"
     CDS             875..1618
                     /NRPS_PKS="Domain: PKS_KR (10-184). E-value: 4.5e-10.
                     Score: 31.6. Matches aSDomain:
                     nrpspksdomains_AMK31_RS04200_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994011.1"
                     /locus_tag="AMK31_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04120"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_073939529.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-32, bitscore:
                     108.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPEAPLAGKVALVTGGSRGIGAATVLRLAREGADVALTYVSGKE
                     AAEDVVRAVEATGRRAVALRADSADAEEAAGAVERAASALGGLDVLVNNVGVGLLGPLD
                     GITLADVDRVLAVNVRGVFLASQAAAARMAEGGRIVTIGTCMTQRVPGPGGTLYAMSKA
                     ALTGLTKALARELGPRGITANIVHPGPIDTGMNPADGPYAAGQAAMTALGRFGTADEVA
                     ATVAHLAAASYVTGAEFSVDGGHAA"
     aSDomain        905..1426
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS04200_PKS_KR.1"
                     /evalue="4.50E-10"
                     /label="AMK31_RS04200_PKS_KR.1"
                     /locus_tag="AMK31_RS04200"
                     /protein_end="184"
                     /protein_start="10"
                     /score="31.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGGSRGIGAATVLRLAREGADVALTYVSGKEAAEDVVRAVE
                     ATGRRAVALRADSADAEEAAGAVERAASALGGLDVLVNNVGVGLLGPLDGITLADVDRV
                     LAVNVRGVFLASQAAAARMAEGGRIVTIGTCMTQRVPGPGGTLYAMSKAALTGLTKALA
                     RELGPRGITAN"
     CDS_motif       911..976
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK31_RS04200_0001"
                     /evalue="7.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK31_RS04200"
                     /protein_end="34"
                     /protein_start="12"
                     /score="15.4"
                     /tool="antismash"
                     /translation="LVTGGSRGIGAATVLRLAREGA"
     CDS_motif       1256..1402
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK31_RS04200_0002"
                     /evalue="3.30E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="AMK31_RS04200"
                     /protein_end="176"
                     /protein_start="127"
                     /score="0.5"
                     /tool="antismash"
                     /translation="AAAARMAEGGRIVTIGTCMTQRVPGPGGTLYAMSKAALTGLTKAL
                     AREL"
     gene            complement(1698..2813)
                     /gene="alc"
                     /locus_tag="AMK31_RS04205"
                     /old_locus_tag="AMK31_04125"
     CDS             complement(1698..2813)
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571646.1"
                     /locus_tag="AMK31_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04125"
                     /product="allantoicase"
                     /protein_id="WP_073939001.1"
                     /transl_table=11
                     /translation="MTAIPSFTGDANPYGGGDPYADYRTADLPFTQYANLADRQLGAGV
                     IAANDEFFAQRENLLVPERAEFDPEHFGHKGKVMDGWETRRRRGVSAEHPWPAAEDHDW
                     ALIRLGAPGVIRGIVVDTAHFRGNYPQSVSVEGASVAGSPSPEELLADDVKWTTLVPRT
                     PVGGHAANGFAVSAEQRFTHLRVNQHPDGGIARLRVYGEVVPDPKWLEVLGTFDVVALE
                     NGGQVEDASNLFYSPATNTIQPGRSRKMDDGWETRRRRDQGNDWIRYQLVSQSRIRAIE
                     IDTAYLKGNSAGWASVSVKDGEDGDWREILPRTRLQPDTNHRFVLPEPAVGTHARVDIF
                     PDGGISRLRLFGSLTEEGAQRLAARHQELGG"
     gene            complement(2867..4204)
                     /gene="allB"
                     /locus_tag="AMK31_RS04210"
                     /old_locus_tag="AMK31_04130"
     CDS             complement(2867..4204)
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071203.1"
                     /locus_tag="AMK31_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04130"
                     /product="allantoinase AllB"
                     /protein_id="WP_073939002.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.4e-24, bitscore:
                     80.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDAELVLRSTRVITPEGTRAATVAVARGTITAVLPYDAPVPDGA
                     RLEDLGDHVLLPGLVDTHVHVNDPGRTEWEGFWTATRAAAAGGITTLVDMPLNSLPPTT
                     TVDHLRIKQEVAAAKAHIDVGFWGGALPDNVKDLRPLHEAGVYGFKAFLSPSGVDEFPH
                     LDQEQLARSLAEIAGFGGLLIVHAEDPHHLDAAPQQGGPKYAHFLASRPRDAEDTAIAA
                     LIAQAKRLHARVHILHLSSSDALPLIAAAREEGVRVTVETCPHYLTLTAEEVPDGASEF
                     KCCPPIREAANQDLLWQALADGVIDCVVTDHSPSTADLKTDDFATAWGGISGLQLSLAA
                     VWTEARGRGHGLEDVVRWMSTRTSELVGLNRKGAIEAGRDADFAVLAPDETFTVDPAAL
                     QHRNRVTAYAGRTLSGVVKSTWLRGERIYADGEFTDPRGHLLTRTP"
     misc_feature    4367..4380
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.91"
                     /tool="antismash"
     misc_feature    complement(4381..4397)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.46"
                     /tool="antismash"
     gene            4486..5289
                     /locus_tag="AMK31_RS04215"
                     /old_locus_tag="AMK31_04135"
     CDS             4486..5289
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530714.1"
                     /locus_tag="AMK31_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04135"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_073939003.1"
                     /transl_table=11
                     /translation="MPTSSASTTDSARSANGGGGVQSLERAFDLLERMADAGGEVGLSE
                     LSASSGLPLPTIHRLMRTLVACGYVRQQPNRRYALGPRLIRLGESASRLLGTWARPYLA
                     RLVEETGETANMALLDGDEIVYVAQVPSKHSMRMFTEVGRRVLPHSTGVGKALLASFPD
                     DEVRALLARTGMPAATDKTITTADGFLAALDDVRELGYAVDDNEQEIGVRCLAVSVPDS
                     PTTAAISISGPAGRVTEAATERIVPVLQQVARELSEALASSTGAA"
     gene            complement(5370..5684)
                     /locus_tag="AMK31_RS04220"
                     /old_locus_tag="AMK31_04140"
     CDS             complement(5370..5684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431816.1"
                     /locus_tag="AMK31_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04140"
                     /product="DUF5955 family protein"
                     /protein_id="WP_073939004.1"
                     /transl_table=11
                     /translation="MLRSLGQRPVTGSGEDPRVAELRSAVSRLRRQLAAHPAEFPDRAV
                     AEDELAALAAMTVVGTPEIPRLRRSLLLIAGAIGSVSALSRSLADVRHAVELFGPPPRN
                     "
     misc_feature    complement(5484..5486)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5887..6486
                     /locus_tag="AMK31_RS04225"
                     /old_locus_tag="AMK31_04145"
     CDS             5887..6486
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071199.1"
                     /locus_tag="AMK31_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04145"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_073939005.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.3e-40, bitscore:
                     132.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTEDRIAGVLLAAGGGRRLGGRPKALLEHRGRPLIEHALGVLR
                     AAGCARVHVVLGARADAVRERAELPGCVLVENPEWEQGMGTSLRAGLASLAGTPARAAL
                     VSLVDQPGIGPEAVARVLAAYEDEHSLVSAAYAGVRGHPVLFGAAHWAGIEEAATGDQG
                     ARGYLREHAAEIRLVECGDVAQAYDIDTEADLVHLE"
     gene            6707..8329
                     /gene="aceB"
                     /locus_tag="AMK31_RS04230"
                     /old_locus_tag="AMK31_04150"
     CDS             6707..8329
                     /EC_number="2.3.3.9"
                     /GO_function="GO:0004474 - malate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aceB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133434.1"
                     /locus_tag="AMK31_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04150"
                     /product="malate synthase A"
                     /protein_id="WP_073939006.1"
                     /transl_table=11
                     /translation="MSAPAPSPLAIVDAEPLPRQEEVLTDAALAFVAELHRRFTPRRDE
                     LLARRAERRAEIARTSTLDFLPETAAIRADDSWTVAPAPAALNDRRVEITGPTDRKMTI
                     NALNSGAKVWLADFEDASAPTWENVVLGQLNLIDAYTRSIDFTDERTGKSYALRPNEEL
                     ATVVMRPRGWHLNERHLVVDGRPVPGAFVDFGLYFFHNAQRLLDLGKGPYFYLPKTESH
                     LEARLWNDVFVFAQDYVGIPQGTVRATVLIETITAAYEMEEILYELRDHASGLNAGRWD
                     YLFSIVKNFRDGGEKFVLPDRNAVTMTAPFMRAYTELLVRTCHKRGAHAIGGMAAFIPS
                     RRDAEVNKVAFEKVRADKDREAADGFDGSWVAHPDLVPIAMESFDKVLGDKPNQKDRLR
                     EDVHVEAADLIAVDSLDAKPTYAGLVNAVQVGVRYIEAWLRGLGAVAIFNLMEDAATAE
                     ISRSQIWQWINAGVVLDNGEQVTADLARKVAAEELANIRAEIGEEAFAAGHWHQAHDLL
                     LTVALDEDYADFLTLPAYEQLNG"
     gene            complement(8343..8636)
                     /locus_tag="AMK31_RS04235"
                     /old_locus_tag="AMK31_04155"
     CDS             complement(8343..8636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385728.1"
                     /locus_tag="AMK31_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04155"
                     /product="SelT/SelW/SelH family protein"
                     /protein_id="WP_073939007.1"
                     /transl_table=11
                     /translation="MSGATSDVRRVEIEYCTQCRWLPRAAWLAQELLTTFEAELTELAL
                     KPGTGGVFVVRVNDEVVWDRREQGFPEPTAVKRAVRDRVAPGKPLGHSEKPA"
     gene            complement(8633..9547)
                     /locus_tag="AMK31_RS04240"
                     /old_locus_tag="AMK31_04160"
     CDS             complement(8633..9547)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823965.1"
                     /locus_tag="AMK31_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04160"
                     /product="HipA family kinase"
                     /protein_id="WP_073939008.1"
                     /transl_table=11
                     /translation="MLREVTATRYVAPLHSGGSVPGIVEADDQGSYVVKFTGSAQGRKA
                     LVAEVIVGELARALGLRFPELVLVRFDPAIAAHEPHQEVRELHAASAGVNLGMDYLPGA
                     RDFTPELAEVFDVDPLEAGRIVWLDALTANVDRTVHSSNLMVWPTLGVAPPHLWLIDHG
                     AALVFHHRWGTTDPTKAYDFRHHALGQYGPDVRAADAELRPKVTGELLRAVTDEVPDAW
                     LADEPGFGGPEEVREAYVAYLHARVRSCDAWLPTDFPSREQLAEENARRAARTEQGRPD
                     WLKRVPDLHGKPAAEQDWSVHLG"
     misc_feature    complement(9795..9806)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     gene            9801..11024
                     /locus_tag="AMK31_RS04245"
                     /old_locus_tag="AMK31_04165"
     CDS             9801..11024
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520530.1"
                     /locus_tag="AMK31_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04165"
                     /product="cytochrome P450"
                     /protein_id="WP_073939009.1"
                     /sec_met_domain="p450 (E-value: 9.1e-16, bitscore: 52.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQPIIVLDPAGSDRHAEHRALRAQGPAARVDILGVQAWAVTDP
                     ALLKRLLTSPDVSKDGRAHWPAFAETVTRWPLALWIAVENMFTAYGPDHRRLRRMIAPA
                     FSARRIAAMKDAVDSMVTALLDELAALPPGEPVDLRAHLAYPLPIAVIGHLMGVPESRR
                     EAFRGVVDGVFDTTLTPAEAQANTTALYEQLDRLVADKRRTPGDDMTSLLIAARDHETD
                     GASLTGQELRDTLLLMISAGYETTVNVIDQSIHTLLTRPDQLELVRTGAVGWQDVVEET
                     LRHEPAVKHLPLRYAVNDIALPDGRTIARGEAILASYAAANRHPDWHRDPDTFDAARPD
                     QDHLAFGHGIHYCLGAPLARLEVATVLERLFDRFPHIRLAVPAAELRPVHSLISNGHQT
                     LPVHLHRP"
     misc_feature    9816..9830
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(11042..11518)
                     /locus_tag="AMK31_RS04250"
                     /old_locus_tag="AMK31_04170"
     CDS             complement(11042..11518)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552894.1"
                     /locus_tag="AMK31_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04170"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_073939010.1"
                     /transl_table=11
                     /translation="MKLSGGVEWALHCCVVLTAASEPVPAARLAQLHDVSPSYLAKQMQ
                     ALSRAGLVRSVQGKTGGYVLTRKASDITLLDVVQAVDGAAPAFVCTEIRQRGPLATPPE
                     KCVKPCPIARAMGAADAAWRASLAGVTIADLVTSVETDSGPDALPGIGTWLTGG"
     misc_feature    11535..11548
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            11638..12384
                     /locus_tag="AMK31_RS04255"
                     /old_locus_tag="AMK31_04175"
     CDS             11638..12384
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533866.1"
                     /locus_tag="AMK31_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04175"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_073939011.1"
                     /transl_table=11
                     /translation="MKITVIGGTGLIGSQLVSRLQDAGHDVVSASLSSGVDLLTGAGLD
                     EALADAHTVVNVTNSPTFDEQSPAFFRTSMDNLLAAGERAGVSHQVVLSIVGVDQVPEL
                     DYYRAKTLQEELLRKGPTPYSIVRATQFFEFMDAVLSWTSDAETVRLPATPVQPIASAD
                     VVEALADVAGAEPRNGILEVAGPDVLPLDEIGRITLAARGDGRAVVTDDQAGMFAAVRG
                     DVLVAGPDARLAPTRYQDWLSARLGG"
     gene            complement(12401..12619)
                     /locus_tag="AMK31_RS04260"
                     /old_locus_tag="AMK31_04180"
     CDS             complement(12401..12619)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK31_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK31_04180"
                     /product="hypothetical protein"
                     /protein_id="WP_073939012.1"
                     /transl_table=11
                     /translation="MTGSPERGGPVHVWSTATWNPVRALDERVEGAAEAMGPAASDQAL
                     CTALAFSPDGALPAESLDYRLALWRLG"
     gene            complement(12662..14164)
                     /locus_tag="AMK31_RS04265"
                     /old_locus_tag="AMK31_04185"
     CDS             complement(12662..14164)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119042.1"
                     /locus_tag="AMK31_RS04265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04185"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_241842551.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.5e-42, bitscore:
                     141.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPPAGGDSAAPHDVAARADAYAAAPLLNCLLREVARPVAGRAGV
                     HRLPGCGKLLRVRGGRRPAAPEVRTDGGWHRLDHPGLVELVSEELRRHTGRPNHELPAE
                     MADSRDAVAALLTARAHASTPTDPYARSEQCLITGHPHHPAPKARGGGPAAGWLPYAPE
                     AHARFPLTLLGVREDCVVEEGDPSALDALGEAPPGYRLLPAHPWQLELAGAALTAAFAD
                     GRLIRLGTTAFDTWPTAAIRTVHVPGRDLFLKFSLDVRVTNDIRRLWRHDLLRLTRTDT
                     AVRTAFAALDGPAAWLSDRGYRTAGFAFEELAVLVRDGLRDHVLPGATPCLAAGLVEGF
                     AGSPLDGLADPAAWWEAYLAQVVPPALAAFAGHGVVLEAHLQNCLIACDDDGMPVQALF
                     RDAEGVKLLTDVDRAAGWERLVYCLVVNHLLELADALAERHPGLDPWPAVRRELARHDL
                     PEIAGLLTAPALPAKTNLLLRWTGADGADARYLPLPNPLSTG"
     gene            14328..15821
                     /locus_tag="AMK31_RS04270"
                     /old_locus_tag="AMK31_04190"
     CDS             14328..15821
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119041.1"
                     /locus_tag="AMK31_RS04270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04190"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_073939014.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.9e-33, bitscore:
                     110.6, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRSPTAEAEVAGELAALRPDLAARYAAELPGARAAVLTRLWRAL
                     THEPLPWIERREAAGDGAVLRLRDGRRVHGPAPDPYATGAYVTAVRLDEVVYEDPARLM
                     ADLAVPHGTEFARELGHSVASMALSRAGQPAGERAWPARDWEWEQRVVDGHPYHPGCRS
                     RPGFSVAEQLAYAPEHRPVVGLGLLPVPGEACLVTGDWPADLRDGGRVLVPVHPWQAAH
                     VLKRPAGERLAGHPLMSLRTLALPGGPHVKTALSARLTSSVRDISVGSVAAATALSALA
                     EELADERLHFTRTLGAVTDGSPELAAVLRESPEVYAGAGERVVPVAALPGTGLPGEPGW
                     AAEFARLALTAGLRLLERGVALEAHGQNLLVVLSATGAPLRLVYRDLADIRVSPARLAR
                     HGIRPRVLPELPARVLTDEVTALRRKTFGSLVGGALAGVTGSAAALRAALEAVVRDLPD
                     TPDLAALTGEPLPVKALTLMRLSPGTPGDQWTRLPNPLV"
     gene            15867..17135
                     /locus_tag="AMK31_RS04275"
                     /old_locus_tag="AMK31_04195"
     CDS             15867..17135
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010355149.1"
                     /locus_tag="AMK31_RS04275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04195"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_073939015.1"
                     /transl_table=11
                     /translation="MITRRRLAAGAGALSAALAVGLSLPSTALADETTAGQPKVNLLLD
                     VSGSMRARDIDGQSRMAAAKQAFNEVLDATPEDVRLGIRTLGANYPGDDRKKGCRDTAQ
                     LYPVGPLDRTEAKTAVATLVPTGWTPIGPALLKAADDLDGGTGSKRIVLISDGEDTCAP
                     LDPCEVAREIAAKGIGLTIDTLGLVPNTKMRQQLSCIAEATGGTYTSVEHTDDLADRVN
                     QLVDRAADPVVTPVVTQGGSECAKAPTLESGLYTDREEFGQQRWYRVDLRPGQELRASV
                     SVSADRAVNPGYGVLLRAVTVHEREIVRGEAAGDGRTDVISTGLRYPKPETDEDEDDAS
                     VETVCLQVANSFSPASGVKTTPGLPLELTLDVVDGPSESDDVAAFGLGRGWWLLGALIV
                     AGFLAGVVWGWVSRWRIAVWRTN"
     gene            17135..17926
                     /locus_tag="AMK31_RS04280"
                     /old_locus_tag="AMK31_04200"
     CDS             17135..17926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003993982.1"
                     /locus_tag="AMK31_RS04280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04200"
                     /product="hypothetical protein"
                     /protein_id="WP_073939530.1"
                     /transl_table=11
                     /translation="MRIPRFSKVFGTALLLLGLAVAPAAADGTDAGDAPTEAGTSFRTA
                     TEIDQGQTATADASAGDYLYWSFPADAEQRPTVRATVKLPKTHAAETWQIDVYDGLRRR
                     QACQWGAQTRTAAADAGSVELACVLRTVRAWSEPWANDPLPGTYYVRLTAVGLPTGDLG
                     LPVGAELRVDSKDMGGAAAVDGRLAEPLVPGSAVAAAEPDEDASSAVLSSIEPEDGWAS
                     GWWSDRWVWTAVGGVLAALAGIGGYALTRGSGRPSRVPPNA"
     gene            complement(17994..18617)
                     /locus_tag="AMK31_RS04285"
                     /old_locus_tag="AMK31_04205"
     CDS             complement(17994..18617)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985051.1"
                     /locus_tag="AMK31_RS04285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04205"
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="WP_073939016.1"
                     /transl_table=11
                     /translation="MPPRRSYDQYCSAARALDVIGDRWTLLIVRELLAGPRRYTDLHAD
                     LPGVSTDVLASRLKDMERDGLTTRRRLPPPGAAYVYELTPRGRELLPVLQAVGAWGQAE
                     LGERRPTDAVRAHWFALPLLRGLEGQGVVEVRLDEGEFHLYVGAEDGPLYGDGPAPGEP
                     DARLVLDVGTCTAVARGEAALADAVRDGRVTVTGDGAIAKALRE"
     gene            18700..19908
                     /locus_tag="AMK31_RS04290"
                     /old_locus_tag="AMK31_04210"
     CDS             18700..19908
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-390). E-value:
                     2.1e-53. Score: 173.7. Matches aSDomain:
                     nrpspksdomains_AMK31_RS04290_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007390030.1"
                     /locus_tag="AMK31_RS04290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04210"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_073939017.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2e-52, bitscore:
                     173.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 6.6e-07, bitscore:
                     23.8, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7.5e-08,
                     bitscore: 27.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFRQSSKLSEVCYEIRGPVIEQANALEEAGHSVLRLNTGNPALF
                     GFEAPEEILQDMIRMLPRAHGYTDSRGVLSARRAVAQRYQTLGLEVDVDDVFLGNGVSE
                     LVSMAVQALLEDGDEVLIPAPDFPLWTAVTTLAGGKAVHYLCDEQAEWYPDLADMESKI
                     TDRTKAVVIINPNNPTGAVYPKEIVEGILDLARRHGLMVLADEIYDQILYDDAVHHSAA
                     ALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPKQHARDYLEGLTMLASMRLCANAPAQ
                     YAIQAALGGRQSIADLTAPGGRLHEQRNVAWEKLNEIPGVSCVKPKGALYAFPRIDPKV
                     HPIHDDEKFVLDLLLREKIQVVQGTGFNWPAPDHFRILTLPHADDLEAAIGRIGRFLSG
                     YRQ"
     aSDomain        18799..19869
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK31_RS04290_Aminotran_1_2.1"
                     /evalue="2.10E-53"
                     /label="AMK31_RS04290_Aminotran_1_2.1"
                     /locus_tag="AMK31_RS04290"
                     /protein_end="390"
                     /protein_start="33"
                     /score="173.7"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEILQDMIRMLPRAHGYTDSRGVLSARR
                     AVAQRYQTLGLEVDVDDVFLGNGVSELVSMAVQALLEDGDEVLIPAPDFPLWTAVTTLA
                     GGKAVHYLCDEQAEWYPDLADMESKITDRTKAVVIINPNNPTGAVYPKEIVEGILDLAR
                     RHGLMVLADEIYDQILYDDAVHHSAAALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     KQHARDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIADLTAPGGRLHEQRNVAWEK
                     LNEIPGVSCVKPKGALYAFPRIDPKVHPIHDDEKFVLDLLLREKIQVVQGTGFNWPAPD
                     HFRILTLPHADDLEAAI"
     gene            19929..20528
                     /locus_tag="AMK31_RS04295"
                     /old_locus_tag="AMK31_04215"
     CDS             19929..20528
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972709.1"
                     /locus_tag="AMK31_RS04295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04215"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_073939018.1"
                     /transl_table=11
                     /translation="MGDLFLVRHGETEWSRSGRHTGSTDVPLTEHGREEARRLVPLIRS
                     HRIGAAFVSPLQRARETAELIGLQEVRVDADLREWDYGAYEGVTTVEIQRERPGWFLFR
                     DGVAPGPAARPGETPEQIGERADRMLGKVDAALANTEGAVVLVAHGHILRVLTARRLGL
                     PPHDGALFQLATGALCRLGTEHGRPVIAGWNVRPPS"
     gene            20575..21204
                     /locus_tag="AMK31_RS04300"
                     /old_locus_tag="AMK31_04220"
     CDS             20575..21204
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996676.1"
                     /locus_tag="AMK31_RS04300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04220"
                     /product="hypothetical protein"
                     /protein_id="WP_073939019.1"
                     /transl_table=11
                     /translation="MTRPPTAAQRRVVDAADPVTGRLKGTEAQLAALVKRGLAFRHPRP
                     PHDHFLTPAGHRLREAEPTAPPPPPAPAERTGVFAARLGGEEDVPASGPARVREVHSAW
                     QGLLELRRMTNPDGATDRPCGWERTHLVQAAALALEAAGHRPEGPGSPGYRVRATPQPE
                     AVAVHEPDTEALRACAATLEGAGWQAGEHTEPRTRARYLLASPRRA"
     gene            21258..21680
                     /locus_tag="AMK31_RS04305"
                     /old_locus_tag="AMK31_04225"
     CDS             21258..21680
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972711.1"
                     /locus_tag="AMK31_RS04305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04225"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_073939532.1"
                     /sec_met_domain="4HBT_2 (E-value: 1.7e-25, bitscore: 85.0,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPFSVPVTVRGYETDTQGHLNQAVYLNYAEHARWSLLQAAGIR
                     QAALQAKGVGPVALETTIRYLRELLAGDEVEVTCEFVWGDGKTFRIRQHIVKADGTVAA
                     EIEAVGGLLDLKERRLLPDPRERFKELAADPAVFGL"
     gene            21686..22297
                     /locus_tag="AMK31_RS04310"
                     /old_locus_tag="AMK31_04230"
     CDS             21686..22297
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125449.1"
                     /locus_tag="AMK31_RS04310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04230"
                     /product="exonuclease"
                     /protein_id="WP_073939020.1"
                     /transl_table=11
                     /translation="MATRHVKPSLYISVDIEADGPIPGPYSMLSLGAAVAGVQDADGFT
                     AADPERRTFYRELRPISDEFVPEALTVSGLDRDRLRAEGLDPALALAQFVRWVREVGAE
                     AGAQPVMCGYPASYDWTFLYWYLIRFTGESPFGHSGCLDMKTLYATKAGVPLRAVAKRS
                     MPPETLPRRRHTHHALDDAVEQAELLINLMKWPGPGSSPR"
     gene            complement(22260..23675)
                     /locus_tag="AMK31_RS04315"
                     /old_locus_tag="AMK31_04235"
     CDS             complement(22260..23675)
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996701.1"
                     /locus_tag="AMK31_RS04315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04235"
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_073939531.1"
                     /transl_table=11
                     /translation="MSPEDPTARSGVHPVDEKLPPLKMATTGLQHVAAMYAGVVAPPLI
                     VGAAIGLSGTELTFLTGACLFTAGLATFLQTLGIWKIGARLPFVNGVTFAGVAPMTAIV
                     AATDDKSDALPIIFGAVIVAGLLGFLAAPFFSKAVRFFPPVVTGTVITLIGISLLPVAF
                     GWAQGSSPTADDFGSVTNLGLAGATLVIVLLLRRFTRGFVKQIAVLLGLVAGTLVAIPL
                     GVTDFSPVADADIVGFPTPFHFGAPQFQLAAILSMCVVMVVSMTESTADMLALGEIVDR
                     PADERTIAAGLRADTLGSAISPVFNGFMCSAFAQNIGLVAMTRIRSRFVVAAGGGFLVL
                     MGLCPVAASLIAVVPRPVLGGAGVVLFGSVAASGIQTLVRAGLDKDNNVLIVAVSLAVG
                     IIPITAPEFYHAFPETAKIVLDSGISTGCVAAVLLNFVFNHLGKGRDAQDVTHPMEAGE
                     EITGATTRAPATS"
     gene            complement(23931..25316)
                     /locus_tag="AMK31_RS04320"
                     /old_locus_tag="AMK31_04240"
     CDS             complement(23931..25316)
                     /EC_number="3.5.4.32"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191365.1"
                     /locus_tag="AMK31_RS04320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04240"
                     /product="8-oxoguanine deaminase"
                     /protein_id="WP_073939021.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.3e-61, bitscore:
                     203.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPSAAQRIVIENCAIATVDAGDTEYASGYLVLAGNRIESVGAGR
                     APEGLENVVRRIDASGHLATPGLVNTHHHFYQWITRGLATDHNLFNWLVALYPTWARID
                     ERMTYAAAQGSLAMMARGGVTTAMDHHYVFPHGSGDISGSIIRAAAEMGVRFTLARGSM
                     DRSEKDGGLPPDFAVETLEGALAATEETVKQHHDASFDAMTQVAVAPCSPFSVSTELMR
                     EGAELARRLGVRLHTHGSETVEEEKFCHELFGMGPTDYFESTGWLGEDVWMAHCVHMTD
                     SDIAAFARTKTGVAHCPSSNARLAAGIARVPDMLRSGVPVGLGVDGTASNESGELHTEL
                     RNALLINRLGTHREAALNARQALRLGTFGGAQVLGRAEQIGSLEPGKLADVVLWRMDTL
                     AHASIADPVTALVFGAAAPVTASFVNGRQIVEGGRLLTVDEDAVARSTREEAQRLARIA
                     AQG"
     gene            complement(25386..26798)
                     /locus_tag="AMK31_RS04325"
                     /old_locus_tag="AMK31_04245"
     CDS             complement(25386..26798)
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961386.1"
                     /locus_tag="AMK31_RS04325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04245"
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_073939022.1"
                     /transl_table=11
                     /translation="MAQPAQGPVKAPCSTPPVHTEDAVTSVHPVDEKLHPSRLVPAALQ
                     HIAAMYAGVVTPPLIIGQACGLDVAARTRLIAASLLIAGVATILQTIGVKGFVGNRLPF
                     VNAASSAGIAPILAIAETNDPGRQLPAIYGAVMVAGVFCLAVGPFFGRLLRFFPPLVTG
                     VVITLIGVTLMPVPVSWAQGGDKTAADFGAMRYLALAGFTLAVILLVQRFGRGFVKQVA
                     LLFGLLVGTLAAIPFGMADFSALKSAPVAALPAPFAFGAPEFQPAAILSLCIVMLVLMT
                     ESSAGMLALGEICDRRANAGTITRGLRTDGIATLIGPVFGGFPTSAFAQNVGVVSLTRV
                     RSRYVVAVAGATLLVLGAFPVLGAVVSLVPMPVLGGAGIVLFGSIAVSGIRTLSEAGLD
                     DSSNIILVAVALGAGIIPLAAPTFYADFPAWAQTVLGSGISAGALVAVTLNLFFHHLGT
                     RSRRPAPALKSS"
     gene            complement(26863..27786)
                     /gene="pucL"
                     /locus_tag="AMK31_RS04330"
                     /old_locus_tag="AMK31_04250"
     CDS             complement(26863..27786)
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514695.1"
                     /locus_tag="AMK31_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04250"
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_073939023.1"
                     /transl_table=11
                     /translation="MPTILGQNQYGKAENRVVKITRDGATHHIKDLNVSVALSGDMEEV
                     HYSGSNANVLPTDTTKNTVFAFAKEYGIESAEQFGIHLARHFVTSQEPIHRARIRIEEY
                     AWERIETSDANSKFIGADDVKHSFVRKGQEVRVTQITYDGERWEVVSGLKDLVVMNSTN
                     SEFWGYVKDKYTTLQEAYDRILATQVSGRWRFNWTDDEQKMPNWEKSYEQVKKHMLQAF
                     AETYSLSLQQTLYQMGSRIINNRSEIDEVRFSLPNKHHFLVDLEPFGLKNDNEVYFAAD
                     RPYGLIEATILRDGCEARIPVDMTNL"
     gene            complement(27793..28188)
                     /gene="uraH"
                     /locus_tag="AMK31_RS04335"
                     /old_locus_tag="AMK31_04255"
     CDS             complement(27793..28188)
                     /EC_number="3.5.2.17"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310076.1"
                     /locus_tag="AMK31_RS04335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04255"
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_073939024.1"
                     /transl_table=11
                     /translation="MSTSTTASVSTHILDTSVGRPAEGVAVRLSARAGRDADWQALGGS
                     ATDADGRCKDLPALPEGTTHVRLDFAVEPYFEKKQADAQQDAPANRDSGAAVFFPEVAI
                     TFAVVPGEHYHVPLLLNPFGYSVYRGS"
     gene            complement(28193..28708)
                     /gene="uraD"
                     /locus_tag="AMK31_RS04340"
                     /old_locus_tag="AMK31_04260"
     CDS             complement(28193..28708)
                     /EC_number="4.1.1.97"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675821.1"
                     /locus_tag="AMK31_RS04340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04260"
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="WP_073939025.1"
                     /transl_table=11
                     /translation="MTSTSTPPPGLTRFNALQESAAFAALHEACASTSWAKRLLAARPY
                     ASAEDLYAASDAAMADLTETDLAEAMAGHPPIGRPKPGDPTSAREQRGMAGASDALKAE
                     MLELNLAYQEKFGHVFLICATGRTGEQMRDAVKERIGNTPAEEREIVRTELGKINRIRL
                     ARLVEEDA"
     misc_feature    28782..28797
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.55"
                     /tool="antismash"
     misc_feature    complement(28787..28800)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.96"
                     /tool="antismash"
     misc_feature    28787..28801
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.33"
                     /tool="antismash"
     misc_feature    complement(28788..28801)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.52"
                     /tool="antismash"
     misc_feature    28855..28871
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    28875..28889
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: strong, score: 29.3"
                     /tool="antismash"
     gene            complement(28921..29289)
                     /locus_tag="AMK31_RS04345"
                     /old_locus_tag="AMK31_04265"
     CDS             complement(28921..29289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061921.1"
                     /locus_tag="AMK31_RS04345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04265"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073939026.1"
                     /transl_table=11
                     /translation="MTGAGDEPFITAVKPLVDAMGGVMLPPDEAGPDDVVLSWEGVDVV
                     AVRLPQLADSLDHILAAMERKRGMPLADLDRRAKQEIVRSLEARGAFAVRHGVETVAGA
                     LGVSRFTVYNYLNREKEG"
     gene            complement(29286..29537)
                     /locus_tag="AMK31_RS04350"
                     /old_locus_tag="AMK31_04270"
     CDS             complement(29286..29537)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983462.1"
                     /locus_tag="AMK31_RS04350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK31_04270"
                     /product="thiamine-binding protein"
                     /protein_id="WP_073939027.1"
                     /transl_table=11
                     /translation="MRLRVEFTTEPFDLDEAPAHAVVAREVIEAAELDEVDVGPFGNTA
                     EGGADQVLTAVDALLRKALNAGATRVSLQVNVVGEGDR"
     misc_feature    complement(29713..29731)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.11"
                     /tool="antismash"
ORIGIN
        1 caggccaatc gccaatcagc cgagtgaaca acgctccagg ccaatacacc tagccgttct
       61 cggagtctcc gacggtgccg tactcgggcc gccccgccac ctcgtacgac tggatggaca
      121 ccccggcccc ggtgacgctg ccggcggtgc gccggaacgc ggtcgggacg gtgccttcgg
      181 tgaagaagcg gcggccggcg ccgaggacga ccgggaaggt cagcaggtgg agggtgtcga
      241 cgaggccgag gtcgaggagg gatcgtgcca gcgcgccgct gccgtgcagc tggagttcgc
      301 cgtcggtgcg ctccttgagc gcgccgacct cctcggcgag gtcgccgcgc agcacggtgg
      361 tgccggacca tccggggtcg gtgagcgtgc tggaggggac gtacttcggc agccggttca
      421 gggggccggc gaccgggtcg tcggggtcgg tcaccttcgg ccagtacgcg gcgaagatgt
      481 cgtaggtgcg gcggccgagc aggaaggcgc cgacgcgtcc gaagacgtcg tcgacgaacc
      541 gtccgaagtc gtcgtcgacg tacgggaaga cccagccgcc ctgctcgaaa ccgtcgcggg
      601 tgtcctcctg ggggccgccc ggggcctggt agacgccgtc gagggtgacg aagacggtgg
      661 agacgagctt gcccatgacg agtgcccttc ctgggagtgc gcgggtctgc tgtcatcagt
      721 gcagacccgc cggaccggcg caactcgtcg gttcacccgg cgtgcggggc tcccggtggc
      781 cgaggtcgac gtccgttcac cgccggtctc cgggggcggg aacggctgga atggccgcat
      841 gaactcctcg aacaccatga acaccgtgaa ttccatgagc cctgaggcgc ccctcgccgg
      901 caaggtggct ctcgtgaccg gcggcagccg cgggatcggc gcggcgacgg tcctgcggct
      961 cgcccgggag ggcgcggacg tcgccctcac ctacgtcagc gggaaggagg ccgccgagga
     1021 cgtcgtacgg gccgtggagg cgacgggtcg ccgcgcggtg gcgctgcggg ccgactccgc
     1081 ggacgccgag gaggcggcgg gtgcggtgga acgcgccgcg tcggcgctcg gcggtctgga
     1141 cgtgctggtg aacaacgtgg gcgtcgggct gctgggcccg ctggacggca tcacgctcgc
     1201 cgatgtggac cgggtgctgg cggtgaacgt gcgcggggtg ttcctggcct cgcaggcggc
     1261 cgccgcgcgg atggccgagg gcgggcggat cgtcaccatc ggcacctgca tgacccagcg
     1321 ggtgccgggc cccggcggca cgctctacgc gatgagcaag gccgcgctga ccgggctgac
     1381 caaggcgctg gcccgggaac tgggcccgcg cgggatcacg gcgaacatcg tccacccggg
     1441 cccgatcgac accggcatga acccggcgga cggcccgtac gcggccgggc aggcggcgat
     1501 gaccgccctg ggccgcttcg ggaccgccga cgaggtggcg gcgacggtgg cccacctggc
     1561 cgccgcctcg tacgtcaccg gggcggagtt ctcggtggac ggcggccacg cggcctgagg
     1621 ccgcggaccg gctgaaacgc ggggcgcgcc ggtgctgtcc ggccggggcg ccccgcgggt
     1681 cgtgggcggg cggtgggtca gccgcccagt tcctggtggc gggcggccag ccgctgggcg
     1741 ccctcctccg tcagggagcc gaacaggcgc aggcgggaga tgccgccgtc cgggaagatg
     1801 tcgacgcggg cgtgggtgcc gaccgcgggc tccggcagga cgaagcggtg gttggtgtcg
     1861 ggctggaggc gggtgcgggg caggatctcc cgccagtcgc cgtcctcgcc gtccttgacg
     1921 gacaccgagg cccagcccgc gctgttgccc ttcaggtagg ccgtgtcgat ctcgatcgcg
     1981 cggatccggg actgggacac cagctggtag cggatccagt cgttgccctg gtcgcggcgg
     2041 cggcgggtct cccagccgtc gtccatcttg cgggagcggc ccggctggat ggtgttggtg
     2101 gcgggcgagt agaagaggtt ggaggcgtcc tcgacctggc cgccgttctc cagcgcgacg
     2161 acgtcgaagg tgccgaggac ttccagccac ttcgggtcgg gtacgacctc gccgtacacg
     2221 cgcaggcggg cgatgccgcc gtcggggtgc tggttgacgc ggaggtgggt gaagcgctgc
     2281 tccgccgaga cggcgaagcc gttcgccgcg tggccgccca ccggcgtgcg cgggacgagc
     2341 gtcgtccact tcacgtcgtc ggcgagcagt tcctcggggg acggggagcc ggccaccgac
     2401 gcgccctcga cagacaccga ctgcgggtag ttgccgcgga agtgggcggt gtcgacgacg
     2461 atgccgcgga tcacgccggg cgcgccgagg cggatcagcg cccagtcgtg gtcctcggcc
     2521 gccggccagg ggtgctcggc ggagacgccg cggcgccgcc gggtctccca gccgtccatc
     2581 accttgccct tgtggccgaa gtgctcgggg tcgaactcgg cgcgctcggg caccagcagg
     2641 ttctcccgct gggcgaagaa ctcgtcgttg gcggcgatga caccggcgcc gagctgccgg
     2701 tcggcgaggt tggcgtactg ggtgaagggc aggtctgcgg tgcggtagtc cgcgtacggg
     2761 tcaccgcctc cgtaggggtt cgcgtcgccg gtgaagctgg gtatcgccgt cacggtgatc
     2821 agttcttcct ttcgggagtc ggccgccggg tgcgggcggg cggcggtcag ggggtgcggg
     2881 tgagcaggtg cccccgggga tcggtgaatt caccgtcggc gtagatccgc tcgccgcgca
     2941 gccaggtgga cttcacgacg ccgctgaggg tgcggccggc gtaggcggtg acgcggttgc
     3001 ggtgctgcag ggccgccggg tcgacggtga aggtctcgtc gggcgcgagg accgcgaagt
     3061 cggcgtcgcg gccggcctcg atggcgccct tgcggttcag tccgaccagt tccgaggtcc
     3121 gcgtggacat ccagcggacg acgtcctcca ggccgtggcc gcgcccccgg gcctcggtcc
     3181 agacggcggc gaggctcagc tggaggccgg agatgccgcc ccacgcggtg gcgaagtcgt
     3241 cggtcttcag gtcggcggtg gacggggagt ggtcggtgac cacgcagtcg atgacgccgt
     3301 cggcgagcgc ctgccacagc aggtcctggt tggcggcctc gcggatgggc gggcagcact
     3361 tgaactcgct ggcgccgtcg gggacttcct cggcggtcag cgtcaggtag tgcgggcagg
     3421 tctccacggt gacgcggacg ccctcctcgc gggcggcggc gatcagcggc agcgcgtcgc
     3481 tggaggacag gtggaggatg tgcacgcgcg cgtggagccg cttggcctgg gcgatgagcg
     3541 cggcgatcgc ggtgtcctcg gcgtcgcgcg ggcggctggc gaggaagtgc gcgtacttgg
     3601 ggccgccctg ctgcggggcc gcgtcgaggt ggtgcgggtc ctcggcgtgc acgatcagca
     3661 ggccgccgaa tccggcgatc tccgccaggg agcgggccag ctgttcctgg tcgaggtgcg
     3721 ggaactcgtc gacgccggac ggcgacagga acgccttgaa gccgtagacg ccggcctcgt
     3781 gcagcgggcg caggtccttg acgttgtcgg gcagggcgcc gccccagaag ccgacgtcga
     3841 tgtgcgcctt ggccgccgcg acctcctgct tgatgcgcag gtggtcgacc gtggtggtgg
     3901 gcgggaggga gttgagcggc atgtcgacga gggtcgtgat gccaccggcg gccgccgcgc
     3961 gggtggcggt ccagaagccc tcccactcgg tgcggccggg gtcgttcacg tgtacgtggg
     4021 tgtcgacgag gccggggagg aggacgtggt cgccgaggtc ctccaggcgg gcgccgtccg
     4081 gcaccggggc gtcgtacggc agtacggccg tgatggtgcc ccgggcgacc gcgaccgtcg
     4141 cggcgcgcgt tccctcgggc gtgatgacgc gcgtcgagcg cagcaccagt tcagcgtcgg
     4201 acacccggac ccctctcttc gccgccgtgt cacttccggg aaaacgggcg tgaccgccac
     4261 gaaacaaact tcaacactct gttgaatccg cttcggagtc ttcactcccg ctcccccgcc
     4321 gtcaaggggc acactctcca cggtgcaccc tcgacggccg ctctggatgt ttccacaaag
     4381 cggaattaga attccagcaa gcagaacgta gctacgcaca agccaggagt caaccggccg
     4441 ccgggtaggc ttctgacctc ccgccagtcc cgaaaggaac gcgccgtgcc gacgtccagc
     4501 gccagcacca ccgactccgc caggtccgcc aacggcggtg gcggtgtcca gtccctcgag
     4561 cgcgccttcg atctgctgga acggatggcg gacgcgggcg gcgaggtcgg gctcagcgag
     4621 ctctcggcca gcagcggact gccgctgccc accatccacc ggctgatgcg caccctggtc
     4681 gcctgcggct acgtgcgcca gcagcccaac cgccggtacg cgctcggtcc ccgtctgatc
     4741 cgcctcggcg agtccgcctc ccggctgctc ggcacctggg cgcggcccta cctggcccgc
     4801 ctggtcgagg agaccggcga gacggcgaac atggccctgc tcgacggcga cgagatcgtc
     4861 tacgtggccc aggtgccgtc caagcactcg atgcgcatgt tcaccgaggt cggccggcgc
     4921 gtcctgccgc actccaccgg cgtcggcaag gcgctgctcg cgagcttccc ggacgacgag
     4981 gtgcgcgccc tgctggcccg cacgggcatg cccgcggcca ccgacaagac catcaccacc
     5041 gccgacggct tcctcgcggc cctggacgac gtgcgcgagc tcgggtacgc ggtcgacgac
     5101 aacgagcagg agatcggggt ccgctgcctc gcggtgtcgg tgcccgactc ccccaccacc
     5161 gccgcgatct ccatctcggg cccggcgggc cgggtcaccg aggcggcgac cgagcggatc
     5221 gtgccggtgc tccagcaggt ggcgcgggag ctgtcggagg ccctggcgag ctcgaccggc
     5281 gccgcctgac cctccctgcg ggacctcacc cgaacagccg aacagcccct ggccgggaag
     5341 gccaggggct gttctcgtat cgacccggat cagttccgcg gcggcggccc gaacagctcc
     5401 accgcgtgcc gtacgtcggc cagcgaccgc gacagcgcgc tgaccgaccc gatcgcaccg
     5461 gcgatcagca gcagcgagcg ccgtaaccgg gggatctcgg gcgtcccgac gacggtcatc
     5521 gcggcgagcg cggcgagttc gtcctcggcg accgcccggt ccgggaactc ggcggggtgg
     5581 gcggcgagct gacggcgcag ccgggacacc gcgctccgca gttccgccac tctcgggtcc
     5641 tcgccgctgc cggtcaccgg cctctgcccc aagctccgca acacagctct cccccctggc
     5701 acacccttgt gcccgtaccg ttcactcccc ctgtgcgccc cccgcacgaa tcgggcgccg
     5761 gggatgtgcg ggtcagtaaa cgccaccggg tgcgcgagcg ccaccacgag gagagaaatt
     5821 gagtccgcga ggacgacccg gtcgagccct tgtccggtat gcgggagcgt ccggtatgca
     5881 ggagccatga ctgacaccga ggaccggatc gccggggtgc tgctcgcggc gggcggcgga
     5941 cgccggctcg gcggacgccc caaggccctg ctggaacacc gggggcggcc gctgatcgaa
     6001 cacgcgctgg gggtgctgcg ggcggccggc tgcgcccgcg tccacgtggt gctgggggcg
     6061 cgcgccgacg ccgtacggga acgggccgag ctgcccggat gcgtactcgt ggagaacccg
     6121 gagtgggagc aaggcatggg cacctcgctg cgggccgggc tcgcctcgct ggccgggacg
     6181 ccggcccgcg cggcgctggt gtcgctggtg gaccagcccg gcataggacc ggaggcggtg
     6241 gcccgggtgc tcgcggcgta cgaggacgag cactccctgg tctcggcggc gtacgccggg
     6301 gtacgcggac accctgtgct gttcggggcg gcgcactggg cgggcatcga ggaggcggcg
     6361 acgggggacc agggcgcccg cggctatctg cgggagcacg cggccgagat ccgcctggtg
     6421 gagtgcggcg acgtcgccca ggcctatgac atcgacaccg aggccgacct ggtccacctt
     6481 gagtgagcgg ggtggcaccc ggcgacacct tgcctcgact cagagaatct cgacatcaac
     6541 aaaccattga agttccacaa tgaggaaact aatatccact gaccagaagc acccgacctc
     6601 ccccactctc ggacacgctc gagcgggggg acccccatcg cgggtgcgat ttcccccatt
     6661 cgtgcccctt ggcacccggt gccaccgctg aaggaagtga cagctcatgt ccgcaccagc
     6721 gccgtccccg ctggccatcg tcgacgccga gcccctgccc cggcaggagg aggtcctcac
     6781 cgacgcggcg ctcgccttcg tggccgagct gcaccggcgg ttcacgccgc gccgcgacga
     6841 actcctcgcc cgccgggccg agcgccgcgc cgagatcgcc cgcacctcca cgctcgactt
     6901 cctgccggag acggccgcca tccgcgcgga cgactcctgg acggtggccc ccgctccggc
     6961 cgcgctgaac gaccgccgcg tcgagatcac cggccccacc gaccgcaaga tgaccatcaa
     7021 cgccctcaac tcgggcgcga aggtctggct cgccgacttc gaggacgcct ccgcacccac
     7081 ctgggagaac gtggtcctcg gccagctcaa cctgatcgac gcctacaccc gcagcatcga
     7141 cttcaccgac gagcgcaccg gcaagtcgta cgccctgcgg ccgaacgagg agctggcgac
     7201 cgtcgtcatg cgcccgcgcg gctggcacct gaacgagcgt cacctggtcg tggacggccg
     7261 gccggtcccc ggcgccttcg tcgacttcgg cctgtacttc ttccacaacg cccagcgcct
     7321 gctcgacctc ggcaagggcc cgtacttcta cctcccgaag accgagtcgc acctggaggc
     7381 ccgcctctgg aacgacgtgt tcgtcttcgc gcaggactac gtcggcatcc cgcagggcac
     7441 cgtccgcgcg accgtgctga tcgagacgat cacggcggcg tacgagatgg aggagatcct
     7501 ctacgagctg cgcgaccacg cctccgggct gaacgcgggc cgctgggact acctcttctc
     7561 catcgtgaag aacttccggg acggcggcga gaagttcgtc ctgccggacc gcaacgcggt
     7621 cacgatgacc gccccgttca tgcgggccta caccgaactc ctggtccgca cctgccacaa
     7681 gcgcggcgcg cacgccatcg gcggcatggc cgcgttcatc ccgtcccgcc gcgacgccga
     7741 ggtcaacaag gtcgccttcg agaaggtccg cgccgacaag gaccgcgagg cggccgacgg
     7801 cttcgacggc tcctgggtcg cccaccccga cctggtgccg atcgccatgg agtccttcga
     7861 caaggtcctc ggcgacaagc ccaaccagaa ggaccggctg cgcgaggacg tgcacgtgga
     7921 ggcggccgac ctgatcgccg tcgactccct cgacgccaag ccgacgtacg cgggcctggt
     7981 caacgccgtc caggtcggcg tgcggtacat cgaggcctgg ctgcgcgggc tcggcgcggt
     8041 cgcgatcttc aacctgatgg aggacgccgc caccgcggag atctcccgct cgcagatctg
     8101 gcagtggatc aacgccgggg tcgtcctcga caacggcgag caggtcaccg ccgacctggc
     8161 gcgcaaggtc gccgccgagg agctggcgaa catccgcgcg gagatcggcg aggaggcgtt
     8221 cgccgcgggc cactggcacc aggcgcacga cctgctgctg acggtcgccc tcgacgagga
     8281 ctacgccgac ttcctgacgc tgccggcgta cgagcagctc aacggctgag ccgcacgcgg
     8341 actcacgcgg gtttctccga gtggcccagg ggtttccccg gggccactcg gtcgcgtacg
     8401 gcccgcttca ccgccgtcgg ctcggggaag ccctgctcgc ggcggtccca gaccacctcg
     8461 tcgttcaccc ggacgacgaa caccccgccc gtgcccggct tgagggccag ttcggtcagc
     8521 tcggcctcga aggtcgtcag cagttcctgc gccagccagg ccgcgcgggg cagccagcgg
     8581 cactgggtgc agtactcgat ctccacgcgc cgtacgtcgc tcgtcgcgcc gctcatccca
     8641 ggtgcaccga ccaatcctgt tccgccgccg gcttgccgtg caggtcgggc acccgcttca
     8701 gccagtccgg gcggccctgt tccgtccgcg ccgcgcggcg cgcgttctcc tccgccagct
     8761 gctcccggct cgggaagtcg gtgggcagcc aggcgtcgca ggaccgcacg cgcgcgtgga
     8821 ggtacgccac ataggcctcg cgcacctctt cggggccgcc gaagccgggt tcgtcggcca
     8881 gccaggcgtc cggcacctcg tccgtgacgg cccgcagcag ctccccggtc accttgggcc
     8941 gcagctcggc gtcggccgcg cggacgtccg gcccgtactg accgagggcg tggtgccgga
     9001 agtcgtacgc cttcgtcggg tcggtggtgc cccagcggtg gtggaagacg agcgcggcac
     9061 cgtggtcgat cagccacagg tgcggcggcg ccaccccgag cgtcggccag accatcaggt
     9121 tggagctgtg gaccgtgcgg tcgacgttcg ccgtcagcgc gtccagccag acgatccgcc
     9181 ccgcctccag cggatcgacg tcgaagacct ccgccagctc cggcgtgaag tcacgggcac
     9241 ccggcagata gtccattccg aggttgacgc ccgcgctggc cgcgtgcagc tcgcggacct
     9301 cctggtgcgg ttcgtgcgcg gcgatcgccg ggtcgaagcg gaccaggacc agctcgggga
     9361 agcgcagccc cagggcgcgc gccagctcac ccacgatcac ctcggcgacc agcgccttgc
     9421 ggccctgcgc cgagccggtg aacttcacga cgtaggagcc ctggtcgtcg gcctcgacga
     9481 ttccggggac ggagccgccg gagtgcaggg gcgcgacgta acgggttgcg gtgacctctc
     9541 tcagcatgtc ctcaagccac ccgcctcacc cagcagtccc gtcgacggcc gtccggctgc
     9601 tgcctccggc ctccggcaca cgaagtgagc atagtaaccg ggggtgatcg tcggcgagga
     9661 gcgccgtcct cgttatggcc ggttgacgcc ttgtcctcgt cgggcgcccc gacgaagcat
     9721 gggcccgcgg gtacgcctgg cccaccgcgt tccgtgtacc gagcgcgctt ccgaccacac
     9781 gcaccgagga gtccgcgttc gtgtccgagc agccgatcat cgtcctcgac cccgccgggt
     9841 ccgaccgtca cgccgagcac cgggccctgc gcgcccaggg gcccgcggca cgggtcgaca
     9901 tcctgggcgt ccaggcgtgg gccgtcaccg accccgccct cctcaagcgc ctgctgacca
     9961 gccccgacgt gtccaaggac ggccgcgcgc actggcccgc cttcgccgag accgtcaccc
    10021 gctggccgct cgcgctgtgg atcgcggtgg agaacatgtt caccgcctac ggccccgacc
    10081 accgccgtct gcgccgcatg atcgcccccg ccttcagcgc ccggcgcatc gccgccatga
    10141 aggacgccgt cgactccatg gtgaccgccc tgctcgacga gctggccgcg ctgcccccgg
    10201 gggaaccggt ggacctgcgg gcgcacctgg cgtatccgct gcccatcgcg gtgatcggcc
    10261 atctgatggg ggtgcccgag agccggcgcg aggccttccg cggcgtcgtc gacggcgtct
    10321 tcgacaccac cctcaccccg gccgaggcgc aggccaacac caccgccctg tacgagcagc
    10381 tggaccggct cgtcgccgac aagcgccgca cgcccggtga cgacatgacg tccctgctga
    10441 tcgccgcgcg ggaccacgag accgacgggg ccagcctgac cgggcaggaa ctgcgcgaca
    10501 cgctgctgct gatgatcagc gccggttacg agaccaccgt caacgtcatc gaccagagca
    10561 tccacaccct gctgacccgc cccgaccagc tggagctggt ccgcaccggg gccgtcggct
    10621 ggcaggacgt cgtcgaggag accctccgtc acgagccggc cgtcaagcat ctgcccctgc
    10681 gctacgccgt caacgacatc gccctgcccg acgggcggac catcgcccgc ggcgaagcga
    10741 tcctcgcctc ctacgccgcc gccaaccgcc accccgactg gcaccgcgac cccgacacct
    10801 tcgatgccgc ccgcccggac caggaccacc tggccttcgg gcacggcatc cactactgcc
    10861 tcggcgcacc gctggcccgg ctggaggtcg ccacggtcct ggaacgtctc ttcgaccgtt
    10921 tcccgcacat ccggctcgcc gtgcccgccg ccgagctgcg gccggtgcac tccctcatca
    10981 gcaacggcca ccagaccctc cccgtccacc tccaccgccc ctgaccggcc gccggggagc
    11041 gtcagccccc ggtgagccag gtgccgatgc ccggcagcgc gtccggtccg ctgtcggtct
    11101 ccaccgaggt gacgagatcg gcgatggtga cgccggcgag cgaggcccgc cacgcggcgt
    11161 ccgcggcgcc catcgcgcgg gcgatggggc acggcttcac gcacttctcc ggcggtgtcg
    11221 cgagggggcc gcgctgacgg atctcggtgc agacgaacgc cggagcggcc ccgtcgacgg
    11281 cctggaccac gtccagcagc gtgatgtcgc tcgccttcct ggtcagcacg tatccgccgg
    11341 tcttgccctg cacggaccgc accaggcccg cccgcgacag tgcctgcatc tgcttggcca
    11401 gatagctcgg cgacacgtcg tgcaactggg ccagccgggc ggccggcacc ggttcgctcg
    11461 ccgccgtcag gaccacacag cagtgcagcg cccattccac gccacccgac agtttcattc
    11521 cgccgcctcc ccggttgacc cggatacaga atatccgagt atcatctcgg acatcaggta
    11581 tccgagtttg cgctccgtcg gtgaccgacc tccggtgcgc gaagggaagg cctcaccatg
    11641 aagatcaccg tcatcggcgg caccggcctc atcggctccc agctcgtctc ccggcttcag
    11701 gacgcgggcc acgacgtggt ctccgcgtcg ttgtcctcgg gagtcgacct gctcaccggc
    11761 gccggactcg acgaggcgct cgccgacgcc cacacggtcg tcaacgtcac caactcgccg
    11821 accttcgacg agcagtcccc cgcgttcttc cgcaccagca tggacaacct gctggccgcg
    11881 ggcgagcgcg ccggagtgag ccaccaggtc gtcctgtcga tcgtcggcgt ggaccaggtc
    11941 cccgagctgg actactaccg cgcgaagacg ctccaggagg aactgctgcg caaagggccc
    12001 accccgtact cgatcgtgcg cgccacccag ttcttcgagt tcatggacgc cgtgctgtcc
    12061 tggacctccg acgccgaaac cgtccgcctg cccgccaccc cggtgcagcc gatcgcgtcc
    12121 gccgacgtgg tcgaggccct cgccgacgtg gccggcgcgg agccccgcaa cggcatcctc
    12181 gaggtcgccg gacccgacgt cctcccgctg gacgagatcg gccggatcac cctggccgcc
    12241 cgcggtgacg gccgcgccgt cgtcaccgac gaccaggccg gcatgttcgc cgccgtccgg
    12301 ggcgacgtcc tcgtcgcggg ccccgacgcc cgcctggcgc ccacccgcta ccaggactgg
    12361 ctgagcgccc ggctcggcgg ctgagccccg cctcgcggga tcagccgagt ctccacaggg
    12421 ccaggcggta gtccagggac tcggccggca acgcgccgtc ggggctgaag gccagggcgg
    12481 tacacagggc ctggtccgac gcggccggcc ccatggcctc cgccgccccc tcaaccctct
    12541 cgtccagcgc ccggacgggg ttccaggtgg cggtggacca gacgtggacc ggcccgcccc
    12601 gctcggggga gcctgtcaca ccggcgtgag caagtgccct gcggagcagc tgggttggcg
    12661 gtcagcccgt ggacagcggg ttgggcagcg gcaggtagcg ggcgtcggcg ccgtccgcgc
    12721 cggtccagcg cagcagcagg ttggtcttgg cgggcagggc gggcgcggtg agcaggccgg
    12781 cgatctcggg caggtcgtgc cgggccagtt cgcggcggac ggcgggccac gggtccagcc
    12841 ccgggtggcg ttcggcgagc gcgtcggcca gctccagcag gtggttgacg accaggcagt
    12901 acaccagccg ttcccagccg gccgcgcggt ccacgtcggt cagcagtttc acgccctcgg
    12961 cgtcccggaa cagcgcctgc accggcatgc cgtcgtcgtc gcaggcgatc aggcagttct
    13021 gcagatgggc ctccaggacg acgccgtggc cggcgaaggc ggccagggcg ggcgggacga
    13081 cctgggcgag gtaggcctcc caccaggcgg cggggtcggc gaggccgtcg agcgggctgc
    13141 ccgcgaagcc ctcgacgagt ccggcggcga ggcagggcgt ggcgccgggc aggacgtggt
    13201 cgcgcagtcc gtcgcggacc aggacggcga gttcctcgaa ggcgaatccg gcggtgcggt
    13261 agccgcggtc ggagagccag gcggcgggcc cgtcgagggc ggcgaaggcg gtgcggacgg
    13321 cggtgtcggt gcgggtcagc ctcagcaggt cgtgccgcca cagccggcgg atgtcgttgg
    13381 tgacgcgcac gtcgaggctg aacttcagga agaggtcgcg tccggggacg tggacggtgc
    13441 ggatcgcggc cgtcggccag gtgtcgaacg cggtggtgcc gagccggatc agccggccgt
    13501 cggcgaaggc cgcggtgagc gccgcgccgg ccagttccag ctgccagggg tgcgcgggca
    13561 gcagccggta gccgggcggg gcctcgccga gggcgtccag cgccgacggg tcgccctcct
    13621 cgacgacgca gtcctcgcgc acgccgagca gggtgagcgg gaagcgggcg tgcgcctcgg
    13681 gcgcgtacgg cagccagccg gcggccggtc ccccgccgcg cgccttgggt gccgggtggt
    13741 gcgggtggcc ggtgatcagg cactgctcgg agcgcgcgta cgggtcggtg ggggtgctcg
    13801 cgtgggcgcg cgcggtgagc agggcggcga ccgcgtcgcg gctgtcggcc atctcggcgg
    13861 gcagttcgtg gttgggccgg ccggtgtgcc ggcgcagttc ctcggagacg agctcgacca
    13921 gtccggggtg gtcgaggcgg tgccagccgc cgtccgtgcg cacctcgggc gcggcgggcc
    13981 gccggccgcc gcgcacccgc agcagctttc cgcagcccgg cagccggtgg acgcccgccc
    14041 ggcccgcgac gggccgggcg acctcccgca gcaggcagtt gagcagcggc gcggccgcgt
    14101 acgcgtcggc gcgggcggcg acgtcgtgcg gggctgcgga gtcgccgccg gcgggcgggg
    14161 gcatgaggtc cacgcgatcc actcgttcct acggtcttgc gagggtttcc agtttccgtg
    14221 cctctcgcgg agttccctac ggttctcccg gagacgatca gtatcgccgc cgtcacgccc
    14281 cgccgtgacc cgctcccgct cgccctatcc gtacggagga cccgaccgtg caccgttccc
    14341 ccaccgccga ggccgaggtc gccggtgagc tcgccgccct gcgcccggac ctggcagcgc
    14401 ggtacgcggc cgaactgccc ggcgcccggg cggccgtgct gacccgcctg tggcgggcgc
    14461 tgacgcacga gccgctgccg tggatcgaac gccgggaggc ggccggggac ggcgcggtgc
    14521 tgcggctgcg cgacggccgc cgggtgcacg gcccggcgcc ggacccgtac gcgaccggcg
    14581 cgtacgtcac cgccgtacgg ctcgacgagg tggtgtacga ggacccggca cggctgatgg
    14641 cggacctggc ggtgccgcac ggcacggagt tcgcccggga actcgggcac agtgtggcct
    14701 cgatggcgct gtcccgggcc gggcagccgg ccggggagcg ggcgtggccg gcgcgggact
    14761 gggagtggga gcagcgggtg gtggacgggc acccgtacca cccgggctgc cggtcccggc
    14821 ccggtttctc ggtggccgag cagctggcgt acgcgcccga gcaccggccg gtggtggggc
    14881 tgggcctgct gccggtgccg ggtgaggcgt gcctggtgac cggggactgg ccggcggatc
    14941 tgcgggacgg gggccgggtg ctggtgccgg tgcatccgtg gcaggcggcg catgtgctga
    15001 agcggccggc cggggaacgg ctcgcggggc atccgctgat gtccctgcgc accctcgcgc
    15061 tgccgggcgg gccgcatgtg aagaccgcgc tgagcgcccg gctgacgtcg tcggtgcggg
    15121 acatctccgt ggggtcggtg gccgccgcga cggcgctgtc ggccctcgcg gaggaactgg
    15181 cggacgaacg gctgcacttc acgcgcacac tgggcgcggt cacggacggc tcgcccgaac
    15241 tcgcggcggt gctgcgggag tcacccgagg tgtacgcggg ggcgggtgag cgggtggtgc
    15301 cggtggccgc tctgcccggc accgggctgc ccggggagcc gggctgggcg gcggagttcg
    15361 cgcggctcgc gctgaccgcc gggctgcggc tgctggagcg gggggtggcg ttggaggcgc
    15421 acggccagaa cctgctggtg gtcctgtcgg cgaccggtgc cccgctgcgg ctggtctacc
    15481 gcgatctcgc cgacatccgg gtaagcccgg cccgcctcgc ccggcacggc atccggccgc
    15541 gtgtgctgcc ggaactgccg gcgcgtgtcc tcaccgacga ggtgacggcg ctgcggcgga
    15601 agacgttcgg ttcgctggtg ggcggcgcac tcgccggggt gacgggttcg gcggcggcgc
    15661 tgcgggccgc gctggaggcc gtcgtacggg atctgccgga cacgcccgat ctcgcggcgc
    15721 tgaccgggga gccgctgccg gtgaaggcgc tgacgctgat gcggctgtcg ccggggacgc
    15781 ccggggacca gtggacccgg ctgcccaatc ctctggtgtg acggtccgtt ttggtggaca
    15841 ccccgctcgg tccataagat ccgccgatga tcacaagaag acggctggcg gcaggggccg
    15901 gtgccctgtc cgccgcgctg gcggtggggc tctccctgcc gtccacggcg ctcgccgacg
    15961 agaccacggc cggacagccc aaggtcaacc tccttctgga cgtgagcggt tcgatgcgcg
    16021 cccgcgacat cgacggccag tcccggatgg ccgcggccaa gcaggcgttc aacgaggtgc
    16081 tggacgccac tccggaggac gtccggctcg gcatccgcac gctgggcgcg aactaccccg
    16141 gcgacgaccg caagaagggc tgccgggaca ccgcgcagct ctacccggtc ggcccgctgg
    16201 accgcaccga ggccaagacg gccgtcgcca ccctggtgcc gaccggctgg acgccgatcg
    16261 gtccggcgct gctgaaggcg gccgacgacc tggacggcgg caccggctcc aagcggatcg
    16321 tgctgatcag cgacggtgag gacacctgcg ccccgctcga cccgtgcgag gtcgcccgcg
    16381 agatcgcggc caagggcatc gggctgacca tcgacaccct cggtctggtg cccaacacga
    16441 agatgcggca gcagctcagc tgtatcgcgg aggcgaccgg cggcacctac acctcggtcg
    16501 agcacaccga cgatctcgcc gaccgggtca accagttggt ggaccgggcg gcggacccgg
    16561 tggtgacccc ggtggtcacc cagggcggct cggagtgcgc caaggcgccg accctcgagt
    16621 ccggtctgta caccgaccgc gaggagttcg ggcagcagcg ctggtaccgg gtcgacctgc
    16681 ggccgggcca ggagctgcgc gcctcggtga gcgtgtccgc ggaccgcgcg gtgaaccccg
    16741 gctacggggt gctgctgcgg gccgtcacgg tgcacgaacg cgagatagtg cgcggcgagg
    16801 cggcgggcga cggccgtacg gacgtgatct cgacgggcct gcgctacccc aagccggaga
    16861 ccgacgagga cgaggacgac gcctccgtcg agaccgtgtg cctccaggtg gccaactcct
    16921 tctcgccggc ctccggcgtc aagaccacgc ccggcctccc gctggagctg accctcgacg
    16981 tggtggacgg gccgagcgag tcggacgacg tggccgcctt cggtctggga cgcggctggt
    17041 ggctgctggg cgcgctgatc gtcgccgggt tcctcgccgg tgtggtgtgg ggctgggtgt
    17101 cgcgctggcg gatcgcggtc tggaggacca actgatgcgt atcccgcgtt tctccaaggt
    17161 gttcggtacg gcgctgctcc tgctgggcct ggccgtggct cccgcggccg cggacggcac
    17221 cgacgccggg gacgcgccca ccgaggcggg cacgtccttc cgtacggcca ccgagatcga
    17281 ccaggggcag accgcgacgg cggacgcctc cgcgggcgac tacctgtact ggtcgttccc
    17341 ggcggacgcg gagcagcggc cgacggtccg ggcgacggtg aagctgccca agacgcacgc
    17401 cgccgagacc tggcagatcg acgtgtacga cggtctgcgc cgccgtcagg cctgccagtg
    17461 gggcgcgcag acccgcaccg ccgcggcgga cgcgggcagc gtggaactgg cctgtgtgct
    17521 gcgcacggtg cgggcctggt cggagccgtg ggcgaacgac ccgctgccgg gcacgtacta
    17581 cgtccggctg accgccgtcg gcctgcccac cggggacctg gggctgccgg tcggcgccga
    17641 actgcgggtg gattccaagg acatgggcgg cgcggcggcg gtggacggcc ggctggccga
    17701 gccgctggtg ccgggcagcg cggtggcggc cgcggagccg gacgaggacg cgtcgtcggc
    17761 ggtgctctcg agcatcgagc cggaggacgg ctgggcctcc ggctggtggt ccgaccgctg
    17821 ggtgtggacg gcggtgggcg gtgtgctcgc ggcactggcc gggatcggcg ggtacgcgct
    17881 gacgcgcggc tcggggcgtc cgtcccgggt tccgccgaac gcgtgacccc ctgaacaccc
    17941 ctgggaaggc ccgcccccgc gcgggccttt ctcgtctctc gttccctcgg gtctcattcc
    18001 ctcagggctt tggcgatcgc cccgtcgccg gtcacggtga cccgcccgtc ccgcaccgcg
    18061 tcggccaggg cggcctcgcc gcgcgcgacg gccgtgcagg tgccgacgtc caggacgagc
    18121 ctcgcgtcgg gctcgccggg ggcggggccg tcgccgtaga ggggaccgtc ctcggcgccg
    18181 acgtacagat ggaactcccc ctcgtcgagg cggacttcga cgacaccctg gccctccagc
    18241 ccgcgcagca gcggcagcgc gaaccagtgg gcgcgcaccg cgtcggtggg ccgccgctcg
    18301 cccagctcgg cctgccccca cgcgccgacg gcctggagca ccggcagcaa ctcgcgtccg
    18361 cgcggggtga gttcgtagac gtaggccgcg ccgggcggcg gcagccggcg cctggtggtc
    18421 agcccgtcgc gctccatgtc cttcagccgc gaggcgagga cgtccgtgct gacgcccggc
    18481 aggtccgcgt gcaggtcggt gtagcgtcgc gggccggcca gcagctcacg gacgatcagc
    18541 agggtccagc ggtcgccgat gacgtcgagc gcgcgggcgg cggaacagta ctggtcgtag
    18601 cttcggcgag gtggcatgcg acgcagtcta gacatgttgt tggactttcc aagcgactac
    18661 ttggtaaaac caagtgacac tggttacctg gaggggcgca tggagttccg gcagtcgagc
    18721 aagctcagcg aggtctgtta cgagatccgc ggcccggtca tcgagcaggc caacgcgctg
    18781 gaggaggccg ggcacagcgt gctgcgcctc aacaccggca acccggccct gttcggcttc
    18841 gaggcgccgg aggagatcct ccaggacatg atccggatgc tgccgcgggc gcacggctac
    18901 accgactcgc gcggcgtcct ctccgcccgc cgcgcggtcg cccagcgcta ccagacgctc
    18961 ggcctggagg tggacgtcga cgacgtgttc ctcggcaacg gcgtgtcgga gctggtctcc
    19021 atggccgtcc aggcgctgct cgaggacggc gacgaggtcc tcatccccgc ccccgacttc
    19081 cccctctgga cggcggtgac gaccctcgcg ggcggcaagg ctgtccacta cctgtgcgac
    19141 gagcaggccg agtggtaccc cgacctggcc gacatggagt cgaagatcac cgaccggacc
    19201 aaggcggtcg tgatcatcaa cccgaacaac ccgaccggcg cggtctaccc gaaggagatc
    19261 gtcgagggca tcctcgacct ggcccggcgg cacggcctga tggtcctcgc cgacgagatc
    19321 tacgaccaga tcctctacga cgacgccgtc caccactcgg ccgccgccct cgcccccgac
    19381 ctggtggtgc tgaccttctg cggcctgtcg aagacgtacc gggtggcggg attccgctcc
    19441 ggctggctgg tggtgacggg ccccaagcag cacgcgcgcg actacctgga gggcctgacc
    19501 atgctggcct ccatgcggct gtgcgccaac gcgcccgccc agtacgccat ccaggccgcg
    19561 ctcggcggcc ggcagtccat cgccgacctc accgcacccg gcgggcgcct gcacgaacag
    19621 cgcaatgtgg cctgggagaa gctgaacgag atccccggcg tgtcgtgcgt gaagccgaag
    19681 ggcgcgctgt acgccttccc ccgcatcgac cccaaggtgc acccgatcca cgacgacgag
    19741 aagttcgtcc tggacctgct gctccgcgag aagatccagg tcgtccaggg caccggcttc
    19801 aactggcccg cccccgacca cttccgcatc ctcaccctcc cccacgcgga cgacctggag
    19861 gcggcgatcg gacggatcgg acggttcctg agcggatacc ggcagtaggc cccacgtaac
    19921 ctggccgcat gggtgatctc ttcctcgtgc ggcacggtga gaccgagtgg tcccggtccg
    19981 gacggcacac cggatcgacg gacgtcccgc tgaccgagca cggccgggag gaggcgcggc
    20041 ggctggtgcc gctgatccgc tcccaccgga tcggggccgc gttcgtcagc cccttgcagc
    20101 gggcgcgcga gaccgcggag ctcatcgggt tgcaggaggt gcgggtggac gccgatctgc
    20161 gggagtggga ctacggggcc tacgagggcg tcaccaccgt cgagatccag cgcgagcggc
    20221 ccggctggtt cctgttccgg gacggggtcg cgccggggcc cgcggcgcgg cccggggaga
    20281 cgccggagca gatcggggag cgggccgacc ggatgctggg caaggtggac gcggcactcg
    20341 ccaacaccga gggcgccgtg gtgctggtcg cgcacgggca catcctgcgg gtgctgaccg
    20401 cgcggcggct cggtttgccg ccgcacgacg gggcgctgtt ccagctggcc acgggagcgc
    20461 tgtgccggct gggcacggag cacgggcggc cggtgatcgc cggctggaat gtcagacccc
    20521 cgtcgtagcc ttcgaggcga tgggtcctga cccgccgccg ggaaggagca cgccgtgacc
    20581 cgaccgccca ccgccgcgca gcggcgtgtc gtcgacgccg ccgatccggt caccggacgg
    20641 ctgaagggaa ccgaggcgca gctcgccgca ctggtgaagc gggggctcgc cttccggcat
    20701 ccccggccgc cgcacgacca cttcctcacc ccggccggac accggctgcg ggaggccgag
    20761 cccacggcgc ctcccccgcc gcccgcgccc gccgaacgca ccggcgtctt cgccgcccgt
    20821 ctaggtggtg aggaggacgt gcctgcatcg ggcccggccc gggtccgcga ggtgcacagt
    20881 gcctggcagg gtctgctgga gctgcgccgg atgaccaacc cggacggtgc cacggaccgg
    20941 ccgtgcggct gggagcggac acatctggtg caggccgccg cgctcgccct ggaggccgcc
    21001 ggacaccggc cggagggacc cggctcaccg gggtaccggg tgcgcgccac cccgcagccg
    21061 gaggccgtcg ccgtgcacga accggacacc gaggcgctgc gggcctgcgc ggccacgctg
    21121 gagggggcgg gctggcaggc cggcgagcac acggagccgc ggacccgggc gcgctatctg
    21181 ctggcctccc ctcggcgggc gtgagacccg cgcatgccaa gatcggacga agcaaccgcc
    21241 gaccgacagg ggacatggtg agcacgccgt tttccgtacc ggtgaccgtc cgcgggtacg
    21301 agaccgacac ccagggccac ctcaaccagg ccgtctacct caactacgcc gaacacgccc
    21361 gctggtccct gctccaggcg gccggcatcc gccaggccgc cctccaggcg aagggcgtgg
    21421 gaccggtggc gctggagacg accatccgct acctgcggga gctgctggcg ggcgacgagg
    21481 tcgaggtgac ctgcgagttc gtgtggggag acggcaagac gttccggatc cgccagcaca
    21541 tcgtgaaggc cgacggcacg gtcgccgcgg agatcgaggc ggtcggcggc ctgctcgacc
    21601 tgaaggagcg acggctgctc cccgatccgc gcgaacgctt caaggaactg gccgcggatc
    21661 ccgcggtgtt cgggctctga gccccatggc gacacgacac gtcaagccga gcctgtacat
    21721 ctcggtcgac atcgaggcgg acggcccgat cccagggccg tactccatgc tgagcctggg
    21781 ggcggcggtc gccggtgtgc aggacgccga cgggttcacc gcggccgatc ccgagcggcg
    21841 cacgttctat cgcgaactgc ggccgatcag cgacgagttc gtgcccgagg cgctcacggt
    21901 gagcgggctg gaccgcgacc ggctgcgcgc ggagggcctg gacccggccc tcgcgctcgc
    21961 ccagttcgtc cgctgggtgc gcgaggtggg cgccgaggcg ggcgcccagc cggtgatgtg
    22021 cggctacccg gcgtcgtacg actggacgtt cctgtactgg tacctgatcc gcttcaccgg
    22081 cgagagcccc ttcgggcact ccggctgcct ggacatgaag acgctgtacg cgacgaaggc
    22141 cggcgtcccg ctgcgggccg tcgccaagcg ctccatgcct cccgaaacgc tgccacggcg
    22201 ccgccataca catcacgcac tggacgacgc cgtggagcag gcggaactgt tgatcaacct
    22261 catgaagtgg ccggggcccg ggtcgtcgcc ccggtgatct cctctcccgc ttccatcggg
    22321 tgggtgacgt cctgggcgtc gcggcccttg ccgaggtggt tgaagacgaa gttcagcagg
    22381 acggcggcga cacagccggt cgagatgccg gagtccagga cgatcttcgc ggtctccggg
    22441 aaggcgtggt agaactccgg cgcggtgatc gggatgatgc cgacggccag ggagaccgcc
    22501 acgatcagca cgttgttgtc cttgtccagg ccggcccgca ccagggtctg gatgccgctc
    22561 gcggcgaccg agccgaacag gacgacgccc gcgccgccga ggaccgggcg gggcacgacg
    22621 gcgatgagcg aggcggcgac cgggcacagg cccatcagca ccaggaagcc accgcccgcg
    22681 gcgacgacga accggctgcg gatccgggtc atcgcgacga ggccgatgtt ctgtgcgaag
    22741 gcgctgcaca tgaagccgtt gaagacgggg ctgatggcgg agccgagggt gtcggcgcgc
    22801 agcccggcgg cgatggtcct ctcgtcggcc gggcggtcga cgatctcgcc gagcgcgagc
    22861 atgtcggcgg tcgactcggt catcgagacg accatcacca cgcacatgga gaggatggcg
    22921 gcgagctgga actgcggggc gccgaagtgg aacggcgtcg ggaagccgac gatgtccgcg
    22981 tcggcgacgg ggctgaagtc ggtcacgccg agcgggatcg ccaccagcgt gccggcgacc
    23041 aggccgagca gcacggcgat ctgcttgacg aagccgcggg tgaagcggcg cagcagcagc
    23101 acgatcacca gggtcgcgcc ggccaggccc aggttggtga cggagccgaa gtcgtcggcg
    23161 gtggggctgg atccctgggc ccagccgaag gcgaccggga gcagcgagat gccgatcagg
    23221 gtgatcacgg tgccggtgac gaccggcggg aagaaccgga ccgccttgct gaagaagggg
    23281 gcggcgagga agccgaggag gcccgcgacg atcaccgcgc cgaagatgat cggcagggcg
    23341 tcggacttgt cgtcggtggc ggcgacgatc gcggtcatgg gggcgacacc ggcgaaggtg
    23401 acgccgttga cgaaggggag ccgggcgccg atcttccaga tgcccagggt ctgcaggaag
    23461 gtggcgaggc ccgcggtgaa caggcaggcg ccggtgagga aggtcagttc ggtgccggag
    23521 aggccgatgg ccgcgccgac gatcaggggc ggggcgacga ctcccgcgta catggcggcc
    23581 acgtgctgca ggccggtggt cgccatcttc aggggcggaa gcttctcgtc gacgggatgc
    23641 acgccggaac gcgcggtggg gtcctcgggg gacatgggcg gtacggcttc gggctgagcg
    23701 gccacggcgg ctcctccggt cgggtacacg tcggctctga cgtgggtgtc agggaggtgg
    23761 tgcggttgtg gtcgtgcggg accgttgggg gggtggcgct ggggggaacg gtgaccgttc
    23821 cggggcgcgt gcgtccacac gcgccccgga gacggctgcc gtggatcccg ctcggatcca
    23881 cgggtcccgg ccgggagccg tccctctcgg ccggagtctt gtgaagcggg tcagccctgt
    23941 gcggcgatgc gcgccaggcg ctgggcttcc tcgcgggtgg agcgggcgac ggcgtcctcg
    24001 tcgacggtga gcaggcggcc gccctcgacg atctgccggc cgttgacgaa ggaggcggtc
    24061 accggggcgg cggcgccgaa gaccagcgcg gtcaccgggt cggcgatcga ggcgtgggcg
    24121 agcgtgtcca tcctccacag caccacgtcg gccagcttgc ccggctccag cgagccgatc
    24181 tgctcggcgc ggccgaggac ctgggcgccg ccgaaggtgc cgagccgcag cgcctgacgg
    24241 gcgttcagcg cggcctcgcg gtgcgtgccc aggcggttga tcagcagggc gttgcgcagt
    24301 tcggtgtgga gttcaccgga ctcgttggag gcggtgccgt cgacaccgag gccgaccggg
    24361 acgcccgacc tcagcatgtc ggggacgcgg gcgatgcccg cggcgaggcg ggcgttggac
    24421 gacgggcagt gggcgacgcc ggtcttcgtg cgggcgaagg cggcgatgtc ggagtcggtc
    24481 atgtggacgc agtgcgccat ccacacgtcc tcgccgagcc agccggtgga ctcgaagtag
    24541 tccgtcgggc ccatcccgaa cagctcgtgg cagaacttct cctcctcgac cgtctccgag
    24601 ccgtgggtgt gcagccgcac gccgagccgg cgggccagct cggcgccctc ccgcatgagt
    24661 tcggtggaga cggagaacgg cgagcagggg gcgaccgcca cctgggtcat ggcgtcgaag
    24721 gaggcgtcgt ggtgctgctt gacggtctcc tcggtggcgg cgagcgcacc ctcgagcgtc
    24781 tcgacggcga agtccggcgg caggccgccg tccttctcgc tgcggtccat cgagccgcgg
    24841 gccagcgtga accggacgcc catctcggcg gcggcgcgga tgatcgagcc ggagatgtcg
    24901 ccggagccgt gcgggaacac gtagtggtgg tccatggcgg tggtgacacc gccgcgggcc
    24961 atcatggcga gggatccctg cgcggccgcg tacgtcatcc gctcgtcgat gcgcgcccac
    25021 gtcgggtaca gcgcgaccag ccagttgaac aggttgtggt cggtggccag gccccgggtg
    25081 atccactggt agaagtggtg gtgggtgttg accagaccgg gcgtggccag atggccgctc
    25141 gcgtcgatcc ggcgtaccac gttctccagc ccctcggggg cccggcccgc tccgaccgac
    25201 tcgatgcggt tgccggcgag cacgaggtac ccggaggcgt actcggtgtc gcccgcgtcc
    25261 acggtggcga tcgcacagtt ctcgatgacg atgcgctggg ctgccgatgg tgccatggcg
    25321 cttccttgtc tttcagtggc ggcccgtgaa cggtgaggtg tccacgggga gggcacggca
    25381 ggaccctagg aggatttgag tgccggggcc ggccggcggc tccgggtgcc gagatggtgg
    25441 aagaacaggt tgagggtgac cgcgacgagc gcgccggcgc tgatgccgga tccgagcacg
    25501 gtctgcgccc aggccgggaa gtcggcgtag aaggtcggag cggccagcgg gatgatgccg
    25561 gcgccgagag ccacggccac caggatgatg ttggagctgt cgtcgaggcc cgcctccgac
    25621 agggtgcgga tgccgctgac ggcgatcgag ccgaacagca cgataccggc gccgccgagg
    25681 accggcatgg ggaccaggga gaccaccgcg ccgaggacgg ggaaggcgcc gaggacgagc
    25741 agggtggcgc cggcgacggc gacgacgtag cggctgcgta cccgggtgag ggagacgacg
    25801 ccgacgttct gagcgaaggc ggaggtgggg aagcctccga agaccgggcc gatcagggtg
    25861 gcgatgccgt cggtgcgcag gccgcgggtg atggtcccgg cgttggcgcg gcggtcgcag
    25921 atctcgccga gggcgagcat gccggcgctc gactcggtca tcagcacgag catcacgatg
    25981 cacagcgaca ggatcgccgc gggctggaac tcgggtgcgc cgaaggcgaa cggggcgggc
    26041 agcgcggcga cgggcgccga cttgagggcg ctgaagtcgg ccatgccgaa ggggatggcg
    26101 gccagggtgc cgacgagcag tccgaacagc agggcgacct gcttgacgaa gccgcggccg
    26161 aaccgctgga cgagcaggat gacggcgagg gtgaacccgg cgagcgccag gtacctcatg
    26221 gcgccgaagt cggcggcggt cttgtcgccg ccctgcgccc agctcaccgg gacgggcatc
    26281 agcgtgacgc cgatcagggt gatcaccacg ccggtgacca ggggcgggaa gaagcgcagc
    26341 agccgcccga agaacgggcc gaccgccagg cagaagacgc cggcgaccat caccgcgccg
    26401 tagatcgcgg ggagttggcg gcccgggtcg ttggtctcgg cgatcgcgag gatcggggcg
    26461 atgccggcgg aggaggccgc gttgacgaag ggcagccggt tgccgacgaa gcccttgacg
    26521 ccgatggtct gcaggatggt cgcgacaccc gcgatgagca ggctcgcggc gatcagccgg
    26581 gtgcgggccg cgacgtcgag tccgcaggcc tggccgatga tgagcggagg agtgacaacg
    26641 cccgcgtaca tcgcggcgat gtgctggagc gcggcgggga cgagccgcga ggggtggagc
    26701 ttctcgtcca ccgggtgcac ggacgtgacg gcgtcctcgg tgtgcaccgg cggggtggaa
    26761 caaggggctt tcaccggccc ctgtgcaggc tgtgccatgg tgttccctcc ggtgtggcgc
    26821 gcccccggtc cgggtggccg gaccgggggc gcgcgtcccg cgtcagaggt tggtcatgtc
    26881 gaccgggata cgggcctcgc agccgtcccg caggatggtg gcctcgatca ggccgtaggg
    26941 acggtccgcg gcgaagtaca cctcgttgtc gttcttcagc ccgaacggct ccaggtccac
    27001 caggaagtgg tgcttgttcg ggagggagaa gcggacctcg tcgatctcgc tgcggttgtt
    27061 gatgatccgc gagcccatct ggtacagcgt ctgctgcagc gacagggagt acgtctcggc
    27121 gaaggcctgg agcatgtgct tcttgacctg ctcgtaggac ttctcccagt tgggcatctt
    27181 ctgctcgtcg tcggtccagt tgaaccgcca gcggccggag acctgggtgg ccaggatgcg
    27241 gtcgtacgcc tcctggaggg tcgtgtactt gtccttgacg tagccccaga actcggagtt
    27301 cgtcgagttc atcacgacca ggtccttgag gccggagacg acctcccacc gctcaccgtc
    27361 gtaggtgatc tgggtgacgc ggacctcctg gcccttgcgg acgaaggagt gcttgacgtc
    27421 gtcggcgccg atgaacttgc tgttggcgtc ggaggtctcg atccgctccc aggcgtactc
    27481 ctcgatgcgg atccgcgccc ggtggatcgg ctcctggctg gtgacgaagt gccgggcgag
    27541 gtggatgccg aactgctcgg cggactcgat gccgtactcc ttggcgaacg cgaacaccgt
    27601 gttcttggtg gtgtcggtcg ggagcacgtt ggcgttggag ccggagtagt ggacctcttc
    27661 catgtcgccg ctgagcgcca cggagacgtt caggtccttg atgtggtggg tggcgccgtc
    27721 ccgcgtgatc tttacgactc ggttctcggc cttgccgtac tggttctgtc ccaggatcgt
    27781 gggcattgtc tgctagctcc ctcggtaaac ggagtagccg aacgggttga gcagcagcgg
    27841 tacgtggtag tgctcgcccg gtacgacggc gaaggtgatc gccacctcgg ggaagaacac
    27901 cgcggcaccg ctgtcccgat tcgcgggggc gtcctgctgc gcatcggctt gcttcttctc
    27961 gaagtacggt tcgacggcga agtcgagccg tacgtgggtc gtcccctccg gcagggccgg
    28021 aaggtccttg caccggccgt cggcgtcggt cgcgctgccg ccgagcgcct gccagtccgc
    28081 gtccctgccg gcgcgggcgg agagccggac ggcgacgccc tcggcggggc ggccgacgga
    28141 ggtgtccagg atgtgcgtgg acacggaggc ggtggtgctg gtgctcatgg tgtcaggcgt
    28201 cctcttcgac gagtcgggcc agtcggatgc ggttgatctt ccccagctcg gtgcggacga
    28261 tctcccgctc ctccgccggc gtgttcccga tccgctcctt gaccgcgtcc cgcatctgct
    28321 cgccggtcct gccggtggcg cagatcagga agacgtggcc gaacttctcc tggtaggcca
    28381 ggttcagttc gagcatctcc gccttgagcg cgtcggaggc gccggccatg ccgcgctgtt
    28441 cgcgggcgga ggtcgggtcg ccgggcttgg ggcggccgat cggcgggtgc ccggccatcg
    28501 cctcggcgag gtccgtctcg gtcaggtcgg ccatggcggc gtcgctggcc gcgtacaggt
    28561 cctcggccga ggcgtagggt cgggcggcga gcagccgctt ggcccagctc gtggaggcac
    28621 acgcctcgtg gagcgcggcg aaggccgcgg actcctgaag agcgttgaac cgggtgaggc
    28681 ccggcggcgg cgtggaagtg gaagtcacag gagcctccgt ggccgtttcg gccatcgtgc
    28741 tgaacgggct gcggatagct aacgccctgc gaaacagcac gtcaacactt tgttgaaaat
    28801 tcgcggtaac aaaagcggga tgacaaaagc cgccgccccg gaccgggacg gcggccgcac
    28861 acgactcgcc acgagggccg tccggccctc ctcctcgcgg tttcgatccc gactccggcg
    28921 tcagccttcc ttctcgcggt tgaggtagtt gtagaccgtg aagcggctga cgccgagcgc
    28981 gccggccacg gtctccacgc cgtgccgcac ggcgaaggca ccgcgcgcct ccagggaccg
    29041 cacgatctcc tgcttggccc ggcggtccag gtcggcgagc ggcatgccgc gcttgcgctc
    29101 catggcggcc aggatgtggt cgagggagtc cgcgagctgc ggcagccgta cggccaccac
    29161 gtcgacgccc tcccaggaga gcacgacgtc gtcggggccg gcctcgtcgg gcggcagcat
    29221 caccccgccc atggcgtcga ccagcggctt caccgccgtg atgaagggct cgtcacccgc
    29281 gccggtcacc ggtcaccctc ccccaccacg ttgacctgga gcgagacacg ggtggcgccg
    29341 gcgttcaggg ccttgcgcag cagggcgtcc acggcggtca gcacctggtc ggcgccgccc
    29401 tccgcggtgt tgccgaacgg gccgacgtcg acctcgtcca gctcggcggc ctcgatgacc
    29461 tcacgcgcca ccaccgcgtg cgcgggggcc tcgtcgaggt cgaagggctc ggttgtgaat
    29521 tccactcgca gtcgcacggg ctcaacctaa cgcgcgcggc ggacgttcgg gcaggcctgg
    29581 ggcccggtcc ctcttgacag cctcccgacg tccaggcagt cttcctcacg tcttccggta
    29641 agcagaaatc aacttccgca atgcgaaaga gcagggcgga gggcaagtca ggaagggagc
    29701 gcggatccga tgccaggttt tgaatccagc acagccgcag accagcgctt caacgtcaac
    29761 ctgtcgatcc tcttcacgga actcccgctc ctggagcgcc ccgcggccgc cgccgcggcc
    29821 g
//
