LOCUS       NZ_LIVV01000005        22602 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02009 scaffold5, whole genome shotgun sequence.
ACCESSION   NZ_LIVV01000005
VERSION     NZ_LIVV01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02009
  ORGANISM  Streptomyces sp. CB02009
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 908521)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908521)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905825.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:41:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,214
            CDSs (total)                      :: 8,139
            Genes (coding)                    :: 7,984
            CDSs (with protein)               :: 7,984
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 51 of 155
            Pseudo Genes (incomplete)         :: 117 of 155
            Pseudo Genes (internal stop)      :: 15 of 155
            Pseudo Genes (multiple problems)  :: 26 of 155
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:06:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 143749
            Orig. end                         :: 166351
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVV01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22602
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="2"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..22602
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22602
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12602](-)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12602)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            complement(944..1177)
                     /locus_tag="AMK27_RS20110"
                     /old_locus_tag="AMK27_19825"
     CDS             complement(944..1177)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017239797.1"
                     /locus_tag="AMK27_RS20110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19825"
                     /product="chaplin"
                     /protein_id="WP_073909981.1"
                     /transl_table=11
                     /translation="MNCKKAAAVVAGIIMAMGAATPAFADAGAEGIAVGSPGVLSGNVV
                     QIPIHVPINVCGNSVNVIGALNPAAFNTCANV"
     gene            complement(1348..1761)
                     /locus_tag="AMK27_RS20115"
                     /old_locus_tag="AMK27_19830"
     CDS             complement(1348..1761)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010277780.1"
                     /locus_tag="AMK27_RS20115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19830"
                     /product="rodlin"
                     /protein_id="WP_073909984.1"
                     /transl_table=11
                     /translation="MIKKIMAAAAVTASVVGASAAAASPALAIADDGGTTSLSGNAASQ
                     SFGNSKTVGDMSPQFSAVQGSLNKLCLGVPVKGNVGSVVGVLVPVAVQDINVLSSPQNQ
                     QCAENSTQAKGDEPLSHLLEDIPVLSGNGAYNG"
     misc_feature    complement(1746..1766)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.64"
                     /tool="antismash"
     misc_feature    complement(1787..1801)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            1980..2390
                     /locus_tag="AMK27_RS20120"
                     /old_locus_tag="AMK27_19835"
     CDS             1980..2390
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746400.1"
                     /locus_tag="AMK27_RS20120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19835"
                     /product="rodlin"
                     /protein_id="WP_073909987.1"
                     /transl_table=11
                     /translation="MIKKVMATAAAAVSIVGATAAVASPALAISNDGGTTSLSGNGAHQ
                     EYGNSATYGNMSPQFALVQGSLNKPCIGLPAKVNAGSLIGAIPIAVQDINVLSSPQNQQ
                     CTENSTQAKGDEALSHILDDIPILSGNGVGNN"
     misc_feature    complement(2632..2649)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     misc_feature    2788..2803
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.03"
                     /tool="antismash"
     gene            2806..3846
                     /locus_tag="AMK27_RS20130"
                     /old_locus_tag="AMK27_19845"
     CDS             2806..3846
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035816.1"
                     /locus_tag="AMK27_RS20130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19845"
                     /product="LCP family protein"
                     /protein_id="WP_073909993.1"
                     /transl_table=11
                     /translation="MKFPRSRRPRRPLLVPAVLAAVAALAPGALAAAPTGLPAPAQGLN
                     LLVVGIDSRKGLTAAEKERFRLGGKECDCTDVMMLVHVSAGNDRVDVVSLPRDSLTSFP
                     DRHRDRRTGKLHAAHQAKINGAWSEGGSAFAVETVESMTGLPVHRYLEIDFRRFMDTVD
                     RVDGGVPICTEKALKDPATGIDLQPGTRPVGGGEALQYVRSRKADGQMDFGRIRKQQKF
                     VVNTLERLREDVLHHPGRLKELAETLRGTGATARGITAPELVRLAWRLRNLRPDRTEFA
                     TVPVRGFHPVIAGVGSTVAWDEEGAAEVFRRLREDRPLPAADEVAPSQVSAATYRPAPG
                     ASLICP"
     misc_feature    complement(3881..3896)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    complement(3882..3898)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.05"
                     /tool="antismash"
     misc_feature    complement(3928..3942)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.5"
                     /tool="antismash"
     gene            3941..4348
                     /locus_tag="AMK27_RS20135"
                     /old_locus_tag="AMK27_19850"
     CDS             3941..4348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035815.1"
                     /locus_tag="AMK27_RS20135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19850"
                     /product="rodlin"
                     /protein_id="WP_073909996.1"
                     /transl_table=11
                     /translation="MKKLLATAAVAASVLGATAAGAGQALAIADDGGTTSLSGNGAHQE
                     FGNSATHGNMSPQFALVQGSLNKPCVGLPAKVNAGSLVGLVPIAVQDVNVLSSPQNQQC
                     TENSTQAKGDEPLSHILSDIPVLSGNGAGNS"
     gene            complement(4425..6446)
                     /locus_tag="AMK27_RS20140"
                     /old_locus_tag="AMK27_19855"
     CDS             complement(4425..6446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100998.1"
                     /locus_tag="AMK27_RS20140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19855"
                     /product="thioredoxin domain-containing protein"
                     /protein_id="WP_073909999.1"
                     /transl_table=11
                     /translation="MANRLAHETSPYLLQHADNPVDWWPWSAEAFEEARRRDVPVLLSV
                     GYSSCHWCHVMAHESFEDDATAALVNENFVAVKVDREERPDVDAVYMEAVQAATGQGGW
                     PMTVFLTPDAAPFYFGTYFPPEPRHGMPSFPEVLEGVKGAWADRRDEVGEVAERIVKDL
                     AGRSLAYGGDGVPGEEELAQALLGLTREYDATRGGFGGAPKFPPSMTLEFLLRHHARTG
                     SEGALQMAADTCEAMARGGIYDQLGGGFARYAVDRAWVVPHFEKMLYDNALLCRVYAHL
                     WKATGSDLARRVALETADFMVRELRTPEGGFASALDADSDDGTGRHVEGAYYAWTPDQL
                     TEVLGAEDAALAAAHYGVTEDGTFEHGSSVLQLPQEAGPADADRIASIAARLLAAREER
                     ERPGRDDKVVAAWNGLAIAALAETGALFDRPDLVERATEAADLLVRVHMDESARLTRTS
                     KDGRAGTNDGVLEDYADVAEGFLALAAVTGEGAWLDFAGFLLDLVLDRFTAEGGAFYDT
                     AHDAETLIRRPQDPTDNAAPSGWTAAAGALLSYAAHTGSDAHRAAAEGGLGVVKALGPR
                     APRFIGWGLAVSEALLDGPREIAVVGAPGDAVFQELRRTALLATAPGAVLAFGAPDSEE
                     FPLLKDRPPVAGGPAAYVCRHFTCDAPVTDPEALRRKL"
     gene            complement(6529..8076)
                     /locus_tag="AMK27_RS20145"
                     /old_locus_tag="AMK27_19860"
     CDS             complement(6529..8076)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381884.1"
                     /locus_tag="AMK27_RS20145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19860"
                     /product="hypothetical protein"
                     /protein_id="WP_073910002.1"
                     /transl_table=11
                     /translation="MTTDSITAVEAGPRDRVHAVRHRYAHRGDRATVQDWAYTLYLSVI
                     LGAVYVAPVVYLVRTTEALVSLPTAEAATPVACLVAAAVVGGAQLTGRFWGPLVLKPFL
                     LHVFMSTDLSPTDYLGTIARRRLAYAGLGTLLAVCTATFLTTDLFDRPGSALLPQTLAV
                     AVGIGAVAPAAWLWGQVRTVRENVLLATAVAGAAAATALLGSSSLLGGNGPWLVTGVLA
                     AAAVLLGRSAFRSVRTVDLARLARESARAAEAQTFAWTGTLHHALDLYRPQPRGLTSAL
                     TRPDGRLRGHLAQGAVRAVRTRGRAIAAAVFLPAGGALLTLGVAAPDARLATLSWTAGA
                     VGVYLGSGWVGESWRGLRDELTLAPLLGEWWGGMLARTLAWPVVAVAVPVGLASAVTLL
                     AGRPPQGGPADAVLLTAGSAVLVLGARFLREMKMNLPVELLLPLITPLGDLSALRVFVW
                     QFDGLVVVLAGVLVMNGMPSASGAALVALAAAACCVWAGLRRTGWSLRSLATRLRRA"
     gene            complement(8073..8705)
                     /locus_tag="AMK27_RS20150"
                     /old_locus_tag="AMK27_19865"
     CDS             complement(8073..8705)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970677.1"
                     /locus_tag="AMK27_RS20150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19865"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_073910005.1"
                     /transl_table=11
                     /translation="MSEVPAIAAEDASVVLDGTTLLAPTTFEVKPGEFWCLTGSNGSGK
                     TTLLRAFLGSRRLTDGAVLVRGETVDMARPRHRRLIASLVEPIPVARDMTLREQVTLVA
                     ASWYGNTAETAERADEIVGRLGLTALGTRFPSQLSSGQLQLFNLALTLVRPADVILLDE
                     PERHLDTDRVDLVAALLSERAEQGTSFLVATHEAAMVEACDGLMELG"
     gene            complement(8702..9439)
                     /locus_tag="AMK27_RS20155"
                     /old_locus_tag="AMK27_19870"
     CDS             complement(8702..9439)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970678.1"
                     /locus_tag="AMK27_RS20155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19870"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_073910008.1"
                     /transl_table=11
                     /translation="MSDPSVYDETAIEAYDLVSSMLSPGAGLVAWVSSHRPLDGRTVLD
                     LGCGTGVSSFALAEAGARVVAVDASRPSLDMLEKKRLDRAVEAVEGDFRDLRLDSAFDV
                     VTMSRNTFFLAQEQEEKIELLRGAARHLKPGGAVFLDCTDPAEFQRAGGDAQSVTYPLG
                     RDRMVTVTQTADRAGQHVLSIFLVQGAQTLTAFHEQATWATLAEIRLMARIAGLEVTGV
                     DGSYAGEPYTARSREMLVVLERQ"
     gene            complement(9432..10004)
                     /locus_tag="AMK27_RS20160"
                     /old_locus_tag="AMK27_19875"
     CDS             complement(9432..10004)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970679.1"
                     /locus_tag="AMK27_RS20160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19875"
                     /product="CypD family RiPP peptide-cysteine decarboxylase"
                     /protein_id="WP_073910011.1"
                     /sec_met_domain="Flavoprotein (E-value: 3.3e-11, bitscore:
                     38.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVEKFEGAELHVHVTGSISAALVPWWIHWLREFQPELVVNVSVT
                     PAASRFLAVRALRHLANGAVWVDSWDDPDVPREVNSGKSGASECFLVFPATLDTVMRLA
                     QGRADSPALMMLQLTDAPLVIADTFPGTNEIVENNVRNLKLRPNVEFAPRVNGVRASNR
                     QTAEVGFNLPGALAVANRMRKEGRSGE"
     gene            complement(10001..10561)
                     /locus_tag="AMK27_RS20165"
                     /old_locus_tag="AMK27_19880"
     CDS             complement(10001..10561)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970680.1"
                     /locus_tag="AMK27_RS20165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19880"
                     /product="hypothetical protein"
                     /protein_id="WP_073910014.1"
                     /sec_met_domain="cypI (E-value: 1.4e-30, bitscore: 102.2,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTDRIKGGAATVAVGALAAHLVATVLQNTPDSYNQDMRTFTGGW
                     PVPGWRFFAPNPGVQNVHLLVRETTDDGPTPWRDVTPVVPHGWTQVLYNPRSRGPKALF
                     DAMQQLSIMSANQADFSWVTQSLPYDLVLAASRAAVGDDARALQFLLMNVFPSAPADQR
                     MKPILTSEWIPLGTARRPAGAGA"
     gene            complement(10551..12068)
                     /locus_tag="AMK27_RS20170"
                     /old_locus_tag="AMK27_19885"
     CDS             complement(10551..12068)
                     /NRPS_PKS="Domain: Abhydrolase_1 (264-385). E-value:
                     4.7e-09. Score: 28.1. Matches aSDomain:
                     nrpspksdomains_AMK27_RS20170_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970681.1"
                     /locus_tag="AMK27_RS20170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19885"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_073910017.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-10, bitscore:
                     37.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAGVTLAASAGLVLARGNRKAQIAAAAVIGTCNRLSEIRTPYGR
                     DGADQMTAVITQYRALTALIPDQRLSDDLFLRAVNFQAGLSYAVSGISKAFGSSWVQGD
                     ALLEVLQTEAYGRGPAAAILRRYPRLCRALTVGTVVWETAFPLVYLLPRKQASYALTAV
                     KGFHIGVATAMELPRFVWGFFGSHGAVGYVLDTRGAPRTFEKAVLGIAGGAVLTSALIA
                     REKRRVAEQRRLGPKGAARLRHGDGEVEYRVDRPEEGTPSRAVIVLECGLGQSFESWEW
                     VAASLAEQHTVIRYHRSGYGLTTSRAADGELLAAVLDEVGAEGRIVVATHSIGSLSAAS
                     YLGEEPFAGRVDRLIVVDGTDPVLLDEDRTDRRRLGRFLQAQLYTLVAALTGIYEWAPN
                     AVERQAGYTPDVQYSHVQFVFSPRNVVNSVREYRRMRTEGAVDRLAAVDSVLVVASDEY
                     ADQQAVLAEKLGAKFEVVRGSAHRSIIGYREHAEQVEGAIRRFMDAY"
     aSDomain        complement(10914..11276)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK27_RS20170_Abhydrolase_1.1"
                     /evalue="4.70E-09"
                     /label="AMK27_RS20170_Abhydrolase_1.1"
                     /locus_tag="AMK27_RS20170"
                     /protein_end="385"
                     /protein_start="264"
                     /score="28.1"
                     /tool="antismash"
                     /translation="VIVLECGLGQSFESWEWVAASLAEQHTVIRYHRSGYGLTTSRAAD
                     GELLAAVLDEVGAEGRIVVATHSIGSLSAASYLGEEPFAGRVDRLIVVDGTDPVLLDED
                     RTDRRRLGRFLQAQLYT"
     gene            complement(12420..12602)
                     /locus_tag="AMK27_RS20175"
                     /old_locus_tag="AMK27_19890"
     CDS             complement(12420..12602)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypemycin"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033752.1"
                     /locus_tag="AMK27_RS20175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19890"
                     /product="cypemycin family RiPP"
                     /protein_id="WP_073910020.1"
                     /sec_met_domain="cypemycin (E-value: 3.8e-29, bitscore:
                     96.6, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTSSNSAEALAAQDFANTVLSAAGPGFHADCETPAMATPATPT
                     VAQFVVQGSTICLVC"
     misc_feature    12704..12720
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.19"
                     /tool="antismash"
     misc_feature    complement(12713..12728)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.67"
                     /tool="antismash"
     misc_feature    complement(12752..12767)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     gene            13191..16448
                     /locus_tag="AMK27_RS20180"
                     /old_locus_tag="AMK27_19900"
     CDS             13191..16448
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048013.1"
                     /locus_tag="AMK27_RS20180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19900"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_073910023.1"
                     /transl_table=11
                     /translation="MRDSHRAEAERLWERTVEEELRSSGSRAGAETLLARGRAALDSMA
                     AGAGEEYTAYVRALEEGAPGARTTAHRSSGPLFGGPALVAGVAAVAAVGADLALGTTTG
                     TALGAGAVVAVAGAAATVLKATGGRAEQAAPTAAAAPAAVADGAVEAARARWLTALEVR
                     GMRPFLERERAAPAGGAGDAPPADVAERPSWDRRTPAPRPPERLRGSDRSAAARRRAVL
                     ERSFGHLPDAGGDFAGRREELARITRWVQTGRASAETRPTVVLLHGEPGSGRTALAVRA
                     AHALRDQFRGACVVDLRGGASGERPLATREALLHLLNRLGAPRDRLLFREGATADQQAA
                     RLTELYQRQLTGVPVTVILDDAVDAAQVRALLPERSESLVLVTCREPLDLGDVAAHVLP
                     VAALDAAGAEELLRAAGGAADPGPYDAEALDRIRELCGGLPLALRAAGSLLRRRSMDDL
                     AEVLGRPGWGDAPLERALWARYFVDLDDEARRLLRRLSLAGRASLGAAAAAALLDGSGA
                     DGARLLRELAGAGLLAPVRGERYRLHDAVRGFAAARLLDEEDAAETAAAQERLIRNYAE
                     LADAVIRMVDGKMSTRANRFDGHGFGSLEAALSWLDEESSFITAALRHTDGVDQQTVLD
                     LLGALCDYCLLRGDLYRLGEINELAESVGQGQLSRSVQWRTGIAARQLGELDKARTTLT
                     SVVSLYQEAHQDPGAALALCSLGITLHHQGRLTEAAARLREALALQEPAALAADRGWTL
                     HALAAVERDRGDLAEATALLDRSLALHREHESPHGQAWAHFQRGQVLLLRGDLAGAEAG
                     LREALDGYGRIHDGRGAAWALTQLARARLAAGDAEPAVEGLRGALARHREQEDARGEAW
                     TLFHLAHALEERGDRDDAVRELGRARTMFSRMRDVYGLASARHHSGRVTRDQLAARTGG
                     LRNSGFARQLLVDARADFHRIGVPHGEAWTCLELAVIDAGNARVPQALALCDEARALFG
                     TYGDRRGADWARFLRCTLLPHAVPGNPEPGTVTAREELAALVADRHPARDPRLDDCAEA
                     YAVVLGRGVHPSTPWQAWDLGMVPNRHAREVLGVPVG"
     gene            complement(16562..16798)
                     /locus_tag="AMK27_RS20185"
                     /old_locus_tag="AMK27_19905"
     CDS             complement(16562..16798)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889022.1"
                     /locus_tag="AMK27_RS20185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19905"
                     /product="hypothetical protein"
                     /protein_id="WP_073910026.1"
                     /transl_table=11
                     /translation="MSAHLALTQLVPFAAEELDENKVTPGVLGFVVFAVLALAVWQLMK
                     SMNRHMGKVDFEEAPDPAAAPGAPAPSAGPAGK"
     gene            complement(16800..17681)
                     /gene="mca"
                     /locus_tag="AMK27_RS20190"
                     /old_locus_tag="AMK27_19910"
     CDS             complement(16800..17681)
                     /GO_process="GO:0010126 - mycothiol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mca"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045685.1"
                     /locus_tag="AMK27_RS20190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19910"
                     /product="mycothiol conjugate amidase Mca"
                     /protein_id="WP_073910029.1"
                     /sec_met_domain="PIG-L (E-value: 7.1e-26, bitscore: 87.2,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQLRLMAVHAHPDDESSKGAATMAKYVSEGVDVMVVTCTGGER
                     GSVLNPQLQGDAYVEANIHEVRRKEMDEAREILGVSQEWLGFVDSGLPEGDPLPPLPEG
                     CFALEDVDTAAGELVRKIRSFRPQVVTTYDENGGYPHPDHIMTHKISMVAFDGAADAEK
                     FPEAEFGPVWQPLKLYYNQGFNRPRTVALHEALLARGLESPYGEWLERWKEFGGKERTL
                     TTHVPCAEFFEIRDKALIAHRTQIDPDGGWFRVPMDIQKEVWPTEEYELSKALVPTSLP
                     EEDLFAGIRDNA"
     gene            17780..18181
                     /locus_tag="AMK27_RS20195"
                     /old_locus_tag="AMK27_19915"
     CDS             17780..18181
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035811.1"
                     /locus_tag="AMK27_RS20195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19915"
                     /product="DUF4307 domain-containing protein"
                     /protein_id="WP_073910031.1"
                     /transl_table=11
                     /translation="MSAVREQLPEGRYGRSADEAADRKLRITGAVLGVLFLGLMGWFGW
                     YYVVDSKISAEMIKFDVVSATEVQVHLEIRKDEGVKGVCTLRSRSEDGAEVARKDVRVD
                     EPAGRVDRVYSLRTTARATSAELMGCTAR"
     misc_feature    18280..18297
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.32"
                     /tool="antismash"
     gene            18371..18868
                     /gene="greA"
                     /locus_tag="AMK27_RS20200"
                     /old_locus_tag="AMK27_19920"
     CDS             18371..18868
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0070063 - RNA polymerase binding [Evidence
                     IEA]"
                     /GO_process="GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /gene="greA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101005.1"
                     /locus_tag="AMK27_RS20200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19920"
                     /product="transcription elongation factor GreA"
                     /protein_id="WP_073910034.1"
                     /transl_table=11
                     /translation="MTQTSDNVTWLTQEAYNKLKDELEYLSGPARTEITVKIAAAREEG
                     DLRENGGYHAAKEEQGKQELRIRQLTQLLEHAKVGEAPADDGVVEPGMVVTIAFDGDEN
                     DTTTFLLASREYASGDIETYSPQSPLGVGVNGKKAGDDAEYELPNGKKATVKILSAKPY
                     NG"
     misc_feature    complement(18384..18396)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            19012..21450
                     /locus_tag="AMK27_RS20205"
                     /old_locus_tag="AMK27_19925"
     CDS             19012..21450
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017239791.1"
                     /locus_tag="AMK27_RS20205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_19925"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_073910037.1"
                     /sec_met_domain="Pkinase (E-value: 5e-38, bitscore: 126.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGPLRAGTPRLIGPYELLARLGAGGMGEVFLGRGGGGADGTFVA
                     VKTVRRDVAGDPAFRDRFRREIRVAALVDSAYAAAPLGGDADAEVPWLATAYVPGPSLS
                     QAVRRGGALPVDSVRALGTAVARALADLHRAGVLHRDLKPGNVMLSVDGPRLIDFGIAR
                     SSTATTMTATGLMVGTPSFMSPEHVAGARRVTAASDVFCLGSLLCFAATGEDPFGDGPL
                     AAVLYRVSQAEADLARVPAELRDTVAACLALDPADRPTPEELAELLGGGTPKVFPWPGA
                     VRDHIGEYGTELAQLVASGGPLLEAAPADPGDAAANPDAPGLHSAATRAPVSAPAATGP
                     NGTGDPGDAAGRRRRVRLLAAAVALAVVAGGVGTYLLWPEGGPGKPQPPKAAPVAPRIP
                     GVDGRGLADSSGVVPQNTAQRPAGWKPWQAKLGDPALGCSAGEKVLVCRTTNGRYVALD
                     PASGKQLWDVPAAKDTPDQTYISGKGFPFTAGSATAPMVHDGSVVLVANGSLQVRDART
                     GAVRWQKPAVGPQGLWATRPVVADGIVFAATNVTEDALNVRAALTAFSLADGETIWSEE
                     LTNGETSFAERRAYEPVAYAKGVVYALSQGGLVSYDGRNGTQLGQVEPDAKDCWDIKVL
                     GTSAYCSGAGAGSDTDTALHQLDARTLAPKASLPGGLATAAPTAVGPRAVVAFDGGLRI
                     LDPRTGGTLASFPAGRAPAGLAQSWSSPLLAGDQIVYADYSALHTVRLGADGRPGDLKV
                     TPLPGAPGPRAEEEDYDPSFGNIVARQIREPEVLPVGGIAYVVFDKGAVASVALPGEKE
                     "
     misc_feature    complement(21948..21963)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.81"
                     /tool="antismash"
ORIGIN
        1 aggacggtgg cgctggcggt cggcgtcctg ccgttcatgg agatcccggg gccgctgcgg
       61 ggcctgcccc ggcattacgt cacccactcc agccaccacg gggagctgga ccgcttcgcc
      121 ggccgggacg tgaccgtcgt cggggccggg caggccgcac tggagacggc cgcgctcctc
      181 gtcgaggggg gcgccgcgac cgtacggatc ctcgcccgcg cggaccggct gaactggaac
      241 acgctgcccc cggccctcga ccggggcccg tggccgagcg tgcgcgcgcc gcacacgggg
      301 ctcggctgcg gctggcggaa caagctgtac gcggactccc cgggcgtctt ccgccggctg
      361 ccggccggga cgcgtgagcg gatcttcgac tcggcgctcg gcccggcggg tgcctggtgg
      421 ctgcgggagc ggttcgccgc ggtcggggac gtacgcctcg ggcagcggat caccgcggcg
      481 gcggtgacgg gggacgggcg gctgcggctc gacgtgaccg ggccggaggg ggccgcggtc
      541 ctggagaccg accatgtcgt cgcggccacc gggttcaccc cgagcctgga ccgggccggt
      601 gtgctctcgc ccgagctgcg cggcgcgttg cggacggtcg gcgcgggcgg cgccccggag
      661 gtcggccgtc tcttcgagtc ctcgtggccg ggcctgttcc tggccgggct gctcaccgct
      721 ccttcgtacg gtccgtcgat gcggttcgtc ttcggcgcgg agtacacggc ggggcgtctg
      781 gtgcgcgggg tgcggcggcg gttgcggacg ggggcccggg gcggggcggt gggccggccg
      841 cgtacgggcg ggaaggcgcc ggtctcggca tgagcgaggg ccggcccccg gggagcggac
      901 gctctcccgg ggccggcccc tgtgtctgcg tgccgcggag ggctcagacg ttggcgcagg
      961 tgttgaacgc ggccgggttc agcgcaccga tgacgttcac gctgttgccg cagacgttga
     1021 tcggcacgtg gatcgggatc tggacgacgt tgccggagag gacgcccggc gaaccgacgg
     1081 cgattccctc ggcgcccgcg tcggcgaagg cgggggtcgc cgcacccatg gccatgatga
     1141 ttccggcgac gacggcagca gccttcttac agttcatttc gtctgcatcc tttcggtggc
     1201 ggaacacttt tcacgcaaca caacgatcat gtcgtgcaaa ggaaacccgc gaaatcgacg
     1261 agttccgttc tttcactcca ttgcgcgcac ggacagggcc ggagggaacg cgatcgttcc
     1321 ctccggccct gtcgtgcgcg cgacggatca gccgttgtag gcgccgttcc cggagaggac
     1381 cgggatgtcc tccaggaggt gcgacagcgg ctcgtcaccc ttggcctggg tggagttctc
     1441 cgcgcactgc tggttctgcg gggaggagag gacgttgatg tcctggaccg cgaccgggac
     1501 gaggacgccg acgaccgagc cgacgttgcc cttgaccggg acgccgaggc agagcttgtt
     1561 cagcgagccc tggacggccg agaactgggg gctcatgtcg cccacggtct tggagttgcc
     1621 gaacgactgg ctcgcggcgt tgccgctgag cgaggtggtg ccgccgtcgt cggcgatggc
     1681 gagcgccggg gaggccgccg cagcagaagc gccgacaaca gaggccgtca cagccgcagc
     1741 cgccataatc ttcttgatca cggtgattcc gttcctgttc ccaccaatcg acgtgattga
     1801 tgcgacggga tcaactgcgc gcgggggccg aggttccggc gcttcacccg ttcgactggc
     1861 ccctcgttta gcgctgccga gtgcgctccg ccaagggggt gacacagcgg aacccttgcg
     1921 tccagagcca gttgatcagg cagctccctg cacggagccg gttctagaag ggaactcccg
     1981 tgatcaagaa ggttatggcc actgcggccg cagccgtctc catcgtcggc gccaccgccg
     2041 ccgttgcctc tcccgcgctc gccatctcca acgacggcgg caccacgtcg ctcagcggca
     2101 acggcgccca ccaggagtac ggcaactccg ccacgtacgg caacatgagc ccccagttcg
     2161 cgctggtcca gggctcgctg aacaagccgt gcatcggcct gccggccaag gtcaacgccg
     2221 gttcgctcat cggggccatc ccgatcgcgg tccaggacat caacgtcctg tcctccccgc
     2281 agaaccagca gtgcaccgag aactccaccc aggccaaggg tgacgaggcg ctctcgcaca
     2341 tcctggacga catcccgatc ctctcgggca acggcgtcgg caacaactga cgtcccgcct
     2401 tcgcgcgacg acgtccacac gtcaggggcc gccctccggg gcggcccctt tcgtctgctc
     2461 cgtaccgggc cggcccgtcg ctaccaggtc ggccagaccg gggtcgccat caggcgctcc
     2521 cactcgcggt cgggcatccc cggcaccgtc cggcccgcct gcacccactg ggtcacgagt
     2581 gaggaataga gggggaaagg tgtgcggtcg gccggggccg ggtcgctcac atatcggctc
     2641 ttcggaatga aggccatccg ttcccatttc ccgggatccg gcgccatctt cgctccttcc
     2701 gctgcgattc ccgcatcatt ccacaggcgt cgcgggagag tgattcgtcc tgttcatgtc
     2761 gcgtcgcgta tctgtgtgcg agagtgatcg aattaccgtg cgggcatgaa attcccgcga
     2821 tcacggcgcc cccgacgtcc gctgctcgtc ccggcggtgc tcgccgccgt cgccgccctc
     2881 gcccccggcg ccctcgccgc cgcccccacc ggtctccccg cccccgcaca ggggctgaac
     2941 ctcctcgtgg tcggcatcga cagccgcaag gggctcaccg cggcggagaa ggaacgtttc
     3001 cggctcggcg ggaaggagtg cgactgcacg gacgtcatga tgctcgtgca cgtctcggcc
     3061 gggaacgacc gcgtcgacgt ggtgagcctg ccccgcgact cgctcacctc cttccccgac
     3121 cggcaccgcg accggcgcac cggaaagctg cacgccgccc accaggcgaa gatcaacgga
     3181 gcctggtcgg aaggcggctc cgccttcgcc gtggagaccg tcgagtcgat gacggggctg
     3241 cccgtccacc gctacctgga gatcgacttc cggcgcttca tggacaccgt ggaccgcgtc
     3301 gacggcggcg tccccatctg tacggagaag gccctcaagg acccggccac cggcatcgac
     3361 ctgcagcccg ggaccaggcc ggtcggcggc ggcgaggcgc tccagtacgt gcggtcgcgg
     3421 aaggccgacg ggcagatgga cttcggccgc atccggaagc agcagaagtt cgtggtgaac
     3481 accctggagc ggctccgcga ggacgtcctc caccaccccg gccggctgaa ggaactcgcg
     3541 gagaccctgc gcgggacggg cgcgaccgca cgcgggatca ccgcgcccga gctggtccgg
     3601 ctcgcctggc ggctgcggaa cctgcgcccg gaccgtacgg agttcgccac cgtgcccgta
     3661 cgcggcttcc acccggtcat cgccggtgtc gggtccaccg tcgcctggga cgaggagggg
     3721 gcggccgagg tcttccggcg gctgcgcgag gaccggccgc tgccggcggc ggacgaggtc
     3781 gcgcccagcc aggtctccgc cgccacctac cggccggcgc cgggggcttc gctcatctgc
     3841 ccgtagtccg tccggtggac ttcgcggaac ctccgcaccg ctgaccagtt gatcagcacg
     3901 gctcggcact cagcgggcca cgatccgaaa ggcctgaaca atgaagaagc tgttggctac
     3961 ggctgctgtg gccgcgtcgg tgctcggcgc gacggcggcg ggtgccggac aggcgctcgc
     4021 catcgccgac gacggtggca ccacgtcgct cagcggcaac ggcgcccacc aggagttcgg
     4081 caactccgcc acccacggca acatgagccc gcagttcgcg ctcgttcagg gctccctgaa
     4141 caagccctgc gtcggcctgc cggccaaggt caacgccggt tcgctggtcg gcctcgtccc
     4201 gatcgcggtc caggacgtca acgtcctgtc ctccccgcag aaccagcagt gcaccgagaa
     4261 ctccacccag gccaagggtg acgagccgct ctcgcacatc ctcagcgaca tccccgtgct
     4321 gtccggcaac ggcgccggca acagctgagc gacgacgcac ggcacggcgc ggccccgccg
     4381 cccctcctcg gaggggttgc ggggccgtcc cctttccaga gggctcagag cttccggcgg
     4441 agcgcctccg ggtcggtgac cggcgcgtca caggtgaagt gacggcacac gtacgcggcg
     4501 ggaccaccgg ccaccggcgg acggtccttc aggagcggga actcctcgct gtcgggggcg
     4561 ccgaaggcga ggaccgcgcc gggggcggtc gccaggagcg cggtgcggcg cagttcctgg
     4621 aagacggcgt caccgggggc gcccaccacg gcgatctccc ggggcccgtc gaggagggcc
     4681 tcggagacgg ccaggcccca gccgatgaag cggggcgcgc gcgggccgag tgccttgacg
     4741 acgccgagac cgccctcggc cgcggcccgg tgggcgtccg agccggtgtg cgcggcgtac
     4801 gagagcaggg cgccggcggc ggcggtccag ccggacgggg cggcgttgtc cgtggggtcc
     4861 tgcgggcggc ggatcagcgt ctccgcgtcg tgggccgtgt cgtagaaggc gccgccctcg
     4921 gcggtgaagc ggtccaggac gaggtccagg aggaagccgg cgaagtcgag ccaggcgccc
     4981 tcgccggtga cggcggcgag ggcgaggaag ccctcggcga cgtcggcgta gtcctccagg
     5041 acaccgtcgt tggtgccggc ccggccgtcc ttggacgtgc gggtgaggcg ggcggactcg
     5101 tccatgtgga cccggacgag gaggtcggcg gcctcggtgg cgcgctcgac gaggtcgggg
     5161 cggtcgaaga gggcgccggt ctcggcgagc gcggcgatcg cgagaccgtt ccaggcggcg
     5221 acgaccttgt cgtcgcggcc cggacgctcg cgctcctcgc gggcggcgag gagccgggcg
     5281 gcgatcgagg cgatcctgtc ggcgtcggcc ggaccggcct cctgcgggag ctggaggacg
     5341 gagctgccgt gctcgaaggt gccgtcctcg gtgacgccgt agtgggcggc ggcgagggcg
     5401 gcgtcctccg cgccgaggac ctcggtgagc tggtcgggcg tccacgcgta gtaggcgccc
     5461 tcgacgtgcc ggcccgtacc gtcgtcgctg tccgcgtcca gcgcggaggc gaaaccgccc
     5521 tcgggggtgc gcagttcgcg gaccatgaag tcggcggtct ccagggcgac ccggcgggcc
     5581 aggtcgctgc cggtggcctt ccacagatgc gcgtacaccc ggcagagcag ggcgttgtcg
     5641 tacagcatct tctcgaagtg gggcacgacc caggcgcggt cgacggcgta ccgggcgaag
     5701 ccgccgccga gctggtcgta gatgccgccg cgggccatcg cctcgcaggt gtcggcggcc
     5761 atctggaggg cgccctcgga gccggtacgg gcgtggtggc ggagcaggaa ctccagggtc
     5821 atcgacggcg ggaacttggg ggcaccgccg aagccgccgc gggtcgcgtc gtactcgcgg
     5881 gtcagaccga ggagggcctg ggcgagttcc tcctcgccgg ggacgccgtc gccgccgtac
     5941 gcgagggacc ggcccgcgag gtccttcacg atgcgctccg cgacctcgcc gacctcgtcg
     6001 cgccggtcgg cccaggcgcc cttgacgccc tccaggacct cagggaagga gggcatgccg
     6061 tggcggggct cgggcgggaa gtacgtaccg aagtagaagg gggccgcgtc cggggtgagg
     6121 aagacggtca tcggccagcc gccctggccg gtggcggcct gcacggcctc catgtagacg
     6181 gcgtcgacgt cggggcgctc ctcgcggtcg accttgacgg cgacgaagtt ctcgttgacc
     6241 agggccgcgg tggcgtcgtc ctcgaaggac tcgtgcgcca tgacgtggca ccagtggcag
     6301 gagctgtatc cgacgctgag cagcacgggg acgtcgcggc gccgggcctc ctcgaaggcc
     6361 tcggccgacc acggccacca gtcgaccggg ttgtcggcgt gttgaaggag gtacggggag
     6421 gtctcatggg ccagtcggtt cgccatggtg tccatcctgc cctgccgccc cggagccacg
     6481 cgggacccct gccccaggcg gagcggggtc ggctcccgcg gggcgtcgct acgcccgccg
     6541 gaggcgggtg gcgagggagc ggagggacca gccggtgcgg cgcaggcccg cccagacgca
     6601 gcaggcggcc gcggccaggg ccaccagggc cgcgccggac gcggacggca tcccgttcat
     6661 gacgaggacg ccggccagga cgacgacgag tccgtcgaac tgccagacga agacgcggag
     6721 ggcggagagg tcgcccagcg gtgtgatgag ggggagcagc agttcgacgg gcaggttcat
     6781 cttcatctcg cgcaggaacc tggcgcccag cacgaggacc gcagaccccg ccgtgagcag
     6841 caccgcgtcg gccggtccgc cctggggcgg gcggccggcc aggagggtga cggcgctcgc
     6901 gaggcccacc gggacggcca cggcgacgac cggccaggcc agggtgcggg cgagcatccc
     6961 gccccaccat tcgccgagca gcggggccag ggtcagctcg tcgcgcagtc cgcgccagct
     7021 ctcgccgacc cacccggacc ccaggtagac gccgaccgcg ccggccgtcc aggacagggt
     7081 cgcgagccgg gcgtccggtg cggcgacgcc gagcgtcagc agggcgccgc cggccggcag
     7141 gaacaccgcg gccgcgatcg cccggccccg ggtgcggacc gcgcggaccg cgccctgggc
     7201 gaggtggccg cggagccgcc cgtcggggcg ggtgagggcg gaggtgagcc cgcgcggctg
     7261 cgggcggtac aggtcgagcg cgtggtggag ggtgccggtc caggcgaacg tctgggcctc
     7321 ggcggcgcgc gccgactcgc gggcgagccg ggcgaggtcg accgtacgga cggaccggaa
     7381 ggcggaccgg ccgagcagga cggcggcggc cgcgaggacg ccggtgacga gccacgggcc
     7441 gttcccgccc aggagggagg agctgccgag cagggccgtg gcggccgccg cgcccgccac
     7501 ggcggtggcg agcagcacgt tctcgcgcac cgtccggacc tggccccaca gccatgccgc
     7561 gggggcgacg gcgccgatgc ccacggcgac ggccagggtc tgcggcagca gtgcgctgcc
     7621 cggccggtcg aacaggtcgg tcgtgaggaa tgtcgccgtg cagaccgcca ggagcgtgcc
     7681 gagtcccgcg tacgcgagcc ggcgacgggc gatcgtgccg aggtagtccg tcggggacag
     7741 gtccgtcgac atgaacacgt gcagcaggaa cggcttgagc accagcggtc cccagaaccg
     7801 gccggtgagc tgggcgccgc cgaccaccgc cgccgcgacc aggcacgcca ccggcgtcgc
     7861 cgcctcggcg gtcggcaggg agaccagggc ctccgtggtt cgcaccaggt agacgacggg
     7921 cgccacgtag acggcgccga ggatgacgct gaggtagagg gtgtacgccc agtcctgcac
     7981 cgtggcgcgg tcgccgcggt gggcgtaccg gtgccggacc gcgtggacgc ggtccctggg
     8041 gccggcctcg acggcggtga tgctgtccgt ggtcatccca gctccatgag gccgtcgcag
     8101 gcttccacca tggcggcctc atgggtggcg accaggaacg acgtgccctg ctcggcgcgc
     8161 tcggagagca gggcggcgac gaggtcgacg cggtcggtgt cgaggtgccg ctcgggttcg
     8221 tcgagcagga tgacgtcggc gggccggacc agggtcagcg cgaggttgaa gagctggagc
     8281 tggccggagg agagctggga ggggaagcgg gtgcccagcg ccgtgagccc cagtcgcccg
     8341 acgatctcgt cggcgcgctc ggcggtctcc gcggtgttgc cgtaccagga ggcggcgacc
     8401 agggtcacct gctcgcggag cgtcatgtca cgggcgacgg ggatcggttc gacgagcgag
     8461 gcgatcaggc gccggtgccg gggcctggcc atgtcgacgg tctcgccgcg gacgaggacg
     8521 gcgccgtccg tcagcctccg gctgcccagg aaggcccgca acagggtcgt cttcccggag
     8581 ccgttgctgc cggtgaggca ccagaactcg ccgggcttca cctcgaacgt ggtcggcgcg
     8641 aggagggtgg tcccgtccag gacgaccgag gcgtcctccg cggcgatcgc cggtacttcg
     8701 ctcactgccg ctccagaacg accagcatct cccgcgagcg cgcggtgtag ggctctcccg
     8761 cgtacgaccc gtcgacgccc gtcacctcca gacccgcgat ccgtgccatc agccggatct
     8821 cggccagcgt agcccaggtg gcctgctcgt ggaacgcggt gagcgtctgc gcgccctgga
     8881 ccaggaagat gctcaggaca tgctggcccg cgcggtccgc ggtctgggtc accgtcacca
     8941 tccggtcccg gccgagcggg taggtgaccg actgcgcgtc gccgcccgcg cgctggaact
     9001 cggcggggtc ggtgcagtcg aggaagaccg cgccgcccgg cttcaggtgc cgggcggcac
     9061 cgcgcaggag ctcgatcttc tcctcctgct cctgggcgag gaagaaggtg ttccgggaca
     9121 tcgtgacgac gtcgaacgcg gagtcgaggc ggaggtcgcg gaagtcgccc tccaccgcct
     9181 cgacagcgcg gtcgagacgc ttcttctcca gcatgtccag ggacggccgc gaggcgtcga
     9241 ccgccacgac ccgcgctccg gcctcggcga gcgcgaacga ggacaccccc gtgccgcagc
     9301 ccaggtcgag cacggtccgc ccgtcgaggg ggcggtgcga ggacacccag gcgacgagcc
     9361 cggcccccgg ggagagcatc gacgacacca ggtcgtacgc ctcgatcgcc gtctcgtcgt
     9421 acacgctcgg gtcactcacc ggaacgccct tccttccgca tcctgttggc cacggcgagg
     9481 gcacccggca ggttgaaccc cacctcggcc gtctgccggt tgctcgcgcg tacgccgttg
     9541 acccgcggcg cgaactcgac gttcgggcgg agcttgaggt tccgcacgtt gttctcgacg
     9601 atctcgttgg tccccgggaa cgtgtccgcg atcacgaggg gcgcgtcggt cagctggagc
     9661 atcatgaggg cgggcgagtc cgcgcgcccc tgcgccaggc gcatcacggt gtccagcgtg
     9721 gcggggaaga cgaggaagca ctcggaggcg ccgctcttcc ccgagttgac ctcgcggggc
     9781 acgtccgggt cgtcccagga gtccacccac accgcgccgt tggccaggtg gcggagcgcc
     9841 cggaccgcca ggaaccgcga ggcggcgggc gtcaccgaca cgttgacgac cagttccggc
     9901 tggaactccc tgagccagtg gatccaccac ggcacgagcg ccgcgctgat ggagcccgtg
     9961 acatggacgt gcagctccgc gccctcgaac ttctccacgt tcacgcgccg gctcccgccg
    10021 gccggcgggc ggtaccgagg gggatccact cggaggtgag gatcggcttc atccgctggt
    10081 ccgcgggcgc gctgggaaac acgttcatca gcaggaactg cagtgcccgt gcgtcgtcgc
    10141 ccaccgcggc gcggctcgcc gcgagcacca ggtcgtacgg caggctctgg gtgacccagg
    10201 agaagtcggc ctggttcgcg ctcatgatgg agagctgctg catggcgtcg aagagcgcct
    10261 tgggtccgcg gctccgcggg ttgtacagca cctgcgtcca gccgtgcggc acgacggggg
    10321 tcacgtcgcg ccacggcgtc ggaccgtcgt cggtggtctc ccgcaccagc aggtgcacgt
    10381 tctgcacacc cgggttgggc gcgaagaacc gccagccggg aacgggccag ccgcccgtga
    10441 acgtgcgcat gtcctggttg tacgagtcgg gggtgttctg cagcacggtc gcgaccaggt
    10501 gcgccgcgag cgcaccgacc gcgacggtcg ccgccccgcc cttgatccgg tcagtaagca
    10561 tccatgaacc ttctgatagc gccctcgacc tgttcggcgt gctcccggta cccgatgatc
    10621 gaccggtgcg cggagccgcg taccacctcg aacttcgccc cgagcttctc ggccagcacc
    10681 gcctgctggt ccgcgtactc gtccgaggcg acgaccagga ccgagtcgac cgcggcgagc
    10741 cggtccaccg cgccctcggt gcgcatacgg cggtactcgc ggaccgagtt cacgacgttc
    10801 ctcggcgaga acacgaactg cacgtggctg tactggacgt cgggcgtgta gcccgcctgc
    10861 cgttccaccg cgttgggggc ccactcgtag atcccggtga gcgccgcgac gagcgtgtag
    10921 agctgcgcct ggaggaagcg gccgagccgc ctgcggtccg tgcggtcctc gtccagcagc
    10981 accgggtcgg tgccgtcaac cacgatcagc cggtcgacgc ggcccgcgaa gggctcctcg
    11041 cccaggtacg aggccgcgct cagcgatccg atcgagtggg tggccaccac gatccgcccc
    11101 tcggcgccga cctcgtcgag cacggcggcg agcagctcgc cgtcggccgc gcgggacgtc
    11161 gtgaggccgt atccggaacg gtggtagcgg atgaccgtgt gctgctcggc caggctcgcc
    11221 gcgacccact cccacgactc gaaggactgc ccgaggccgc actccaggac gatcaccgca
    11281 cgggagggag tcccctcctc ggggcggtcc acccggtact ccacctcgcc gtcgccgtgg
    11341 cgcagccgcg cggcgccctt ggggccgagc cggcgctgct cggcgacccg gcgcttctcg
    11401 cgggcgatca gcgcgctcgt gaggacggcg ccgccggcga tgccgaggac ggccttctcg
    11461 aaggtccggg gtgcgccgcg ggtgtccagg acgtagccga cggctccgtg ggagccgaag
    11521 aacccccaga cgaagcgggg cagttccatg gccgtcgcca cgccgatgtg gaagcccttg
    11581 acggccgtga gcgcatagga ggcctgcttg cgcggcagta ggtagacgag cgggaaggcc
    11641 gtctcccaca ccaccgtgcc gacggtgagg gcgcggcaga gccgcgggta cctgcgcagg
    11701 atcgccgcgg cgggtccccg gccgtacgcc tccgtctgca ggacttcgag cagggcgtcg
    11761 ccctggaccc agctgctgcc gaaggccttg gagattcccg agaccgcgta gctcagcccg
    11821 gcctggaagt tgaccgcgcg caggaagagg tcgtcggaga gccgctggtc gggaatcagc
    11881 gcggtgaggg cgcggtactg cgtgatgacc gccgtcatct ggtcggcgcc gtcccgcccg
    11941 tacggggtgc ggatctcgct cagccggttg caggtcccga tgaccgccgc ggcggcgatc
    12001 tgcgccttcc ggttgccgcg ggcgagcacc agtcccgccg atgcggcgag ggtcactccg
    12061 gcgagcacgc gcggagtacg cggatggtcg agtacgcggc ctatccggtg gcgcagtgtt
    12121 cctttcggat actgctgggc cgatgtaccc ctcagatatc cgtcctcttc gaattcttca
    12181 cggaggaaaa gggtctccgc ggccgccagt gcctgtccga ccgcaatcgg aagaaatacg
    12241 cgatcggctg cttcctgggc gcctttcgca ttcgaggcgc gctgccccag ccacttccat
    12301 ttcaccggat tgtccgtctc ccccgtcgca tacctggccg ccgtcgtgag tgctgcggaa
    12361 ccgcgcgccg gagaggcccg tgcgtgacgg gcctctccgg cggcaggctc agtcccgcat
    12421 cagcagacca ggcagatggt gctgccctgg accacgaact gggcgacggt cggcgtggcc
    12481 ggggtggcca tggccggcgt ctcgcagtcc gcgtggaagc ccgggcctgc cgcgctgaga
    12541 acggtgttcg caaagtcctg cgccgccagc gcctcggcgg aattcgagct cgtaagagtc
    12601 atttcagatc gcacttcact aacctttcgt cggtggtcat gcgagcgaat ggtccaggcg
    12661 tatcgaacgt tgccaccccc gtcgcccgct ctgtgtgaac gcgctgcaca acgtttgcaa
    12721 ctggaagctg cggaccgacc ttaggcagac cttcaagaac tcgtcaagcg caattgaccc
    12781 ggcaacttcc gcgtataaca caggacttgg aaagcatcag aagtgacagc tcttttcggc
    12841 cagcattacg gatcctttat acggggcgac tcggaagatt gggggcggtg attccgccgg
    12901 ccgcgaacgg tgtttgggag ggcgccgcgc ggcgaagccc cgtcacccgg gggccgggcg
    12961 ccgcggcccc gggcgccggg acccggcgag ccgggaccgg acggcatccg gccagttctc
    13021 gacccacaac tccccccacc gttcggcatg tcggacgttc cgtcgcggcc acccctcccc
    13081 tctccgctct cgcgccttcg cgccccgcgc agcacactgg acgcgcacgg tccggggcct
    13141 gacagggcct cagggacggg atggtcgggc acgcgcggag ggggacgcac atgcgggaca
    13201 gccatcgggc cgaggctgag cggctgtggg aacggacggt ggaggaggag ctgcggagtt
    13261 ccgggagccg ggcgggcgcg gagaccctgc tcgcccgggg ccgcgccgcg ctggactcga
    13321 tggcggcggg cgccggcgag gagtacacgg cgtacgtacg ggccctggag gagggagcac
    13381 ccggcgcccg caccaccgcg caccgctcct caggcccgct gttcggcggc cccgcgctcg
    13441 tcgcgggagt cgcggccgtc gccgcggtcg gcgcggacct ggcactcggg acgacgacgg
    13501 ggacggcgct cggcgcgggc gcggtggtgg ccgtcgcggg cgcggcggcc accgtgctca
    13561 aggccacggg cggacgtgcc gaacaggccg cgccgacggc cgcggcggcg cccgcggcgg
    13621 tcgcggacgg cgccgtcgag gcggcacggg cgcgctggct gaccgcgctg gaggtacggg
    13681 gcatgcgccc gttccttgag cgggagcggg ccgcacccgc aggcggcgcc ggggacgcac
    13741 ccccggccga cgtggcggag cggccctcct gggaccggcg gacgccggcc ccacggccgc
    13801 ccgagcggct gcgcggctcc gaccggagcg cggcggccag gcgccgggcc gtgctcgagc
    13861 ggtccttcgg ccatctgccc gacgccggag gggacttcgc cggccgacgg gaggaactcg
    13921 cccggatcac ccggtgggtg cagaccgggc gcgcctcggc ggagacccgg ccgacggtgg
    13981 tcctgctgca cggcgagccc gggtcgggac ggacggccct cgcggtacgg gcggcgcacg
    14041 cgctccgcga ccagttccgc ggcgcgtgcg tggtggacct gcggggaggc gcgagcggcg
    14101 agcggcccct ggcgacccgg gaggcgctgc tccatctgct caaccggctc ggcgcaccgc
    14161 gcgaccgtct cctcttcagg gagggcgcca ccgcggacca acaggcggcg cggctcacgg
    14221 agttgtacca gcggcagctg accggcgtgc cggtgacggt gatcctggac gacgccgtgg
    14281 acgcggccca ggtgcgggcg ctgctgccgg agcgttccga gagcctggtc ctggtgacct
    14341 gccgggagcc gctggacctg ggggacgtgg cggcgcacgt cctccccgtg gcggcgctcg
    14401 acgcggccgg ggcggaggag ctgctgcggg cggcgggcgg ggcggcggac cccggcccgt
    14461 acgacgcgga ggcgctcgac cggatccggg agctgtgcgg cggacttccg ctggcgctgc
    14521 gggcggcggg ctccctgctg cgccggcggt ccatggacga cctcgcggag gtgctcggcc
    14581 gcccgggctg gggcgacgcc cctctcgaac gcgccctgtg ggcacggtac ttcgtcgacc
    14641 tcgacgacga ggcgcggcgg ctgctccggc ggctttcgct cgccggccgg gcctccctcg
    14701 gcgccgcggc cgccgccgcg ctgctcgacg ggagcggcgc cgacggcgcc cggctgctgc
    14761 gggagctggc cggcgcggga ctgctcgccc cggtgcgcgg ggagcgctac cggctgcacg
    14821 acgcggtgcg cggcttcgcg gcggcccggc tcctcgacga ggaggacgcg gcggagaccg
    14881 cggcggcgca ggagcggttg atacggaact acgcggagct cgcggacgcg gtgatccgca
    14941 tggtcgacgg caagatgtcg acccgcgcca accgcttcga cggacacggc ttcgggtccc
    15001 tcgaagccgc cctgagctgg ctcgacgagg agtccagctt catcacggcg gcccttcggc
    15061 acacggacgg cgtcgaccag cagaccgtgc tcgatctgct gggcgcgctc tgcgactact
    15121 gcctgctgcg cggcgacctc taccggctcg gcgagatcaa cgaactggcc gagtccgtcg
    15181 ggcagggcca gctgtcccgc tcggtgcagt ggcggaccgg catcgcggcc cggcagctcg
    15241 gcgagctcga caaggcgcgc acgaccctga cgtccgtggt gtcgctctac caggaggccc
    15301 accaggaccc gggggcggcg ctcgcgctct gctcgctcgg catcaccctg caccaccagg
    15361 gccgcctcac ggaggcggcg gcccggctgc gggaggccct cgcgctccag gagccggcgg
    15421 cgctcgccgc cgaccggggc tggacgctgc acgcgctcgc ggccgtggag cgggaccgcg
    15481 gcgacctggc ggaggcgacg gcgctgctcg accggtcgct cgcgctgcac cgggagcacg
    15541 agtccccgca cggccaggcg tgggcgcact tccagcgggg ccaggtgctg ctgctgcggg
    15601 gcgacctggc gggcgcggag gccgggctgc gggaggcgct cgacggctac gggcggatcc
    15661 acgacgggcg cggcgcggcc tgggcgctga cccagctggc cagggcgcgg ctcgccgccg
    15721 gggacgccga gccggccgtc gaggggctgc gcggggcgct cgcccggcac cgggagcagg
    15781 aggacgcgcg cggggaggcg tggacgctgt tccacctggc ccacgccctc gaggagcgcg
    15841 gcgaccggga cgacgcggtg cgggagctgg gcagggcccg gacgatgttc tcgcggatgc
    15901 gggacgtgta cgggctggcc agtgcccggc accattcggg gcgggtcacc cgcgaccagc
    15961 tcgcggcccg caccggcggt ctgcgcaact cgggcttcgc ccggcagctg ctcgtggacg
    16021 cgcgggcgga cttccaccgg atcggggtgc cgcacgggga ggcctggacc tgtctggagc
    16081 tggcggtcat cgacgccgga aacgcccggg tgccgcaggc gctcgcgctg tgcgacgagg
    16141 cccgtgcgct gttcggtacg tacggcgacc ggcggggcgc ggactgggcc cgcttcctgc
    16201 gctgcacgct gctcccgcac gcggtgccgg ggaacccgga gccggggacg gtcacggcgc
    16261 gcgaggagct cgcggcgctg gtcgcggacc ggcatccggc gcgcgatccg cggctcgacg
    16321 actgcgccga ggcgtacgcg gtggtcctgg gccggggcgt ccacccgtcg acgccctggc
    16381 aggcctggga cctgggcatg gtgccgaacc ggcacgcccg ggaggtcctg ggggtaccgg
    16441 tgggatagcc cgccgcggca cgagggcgtc cccgccccgc agcgccgggc ggatggcccg
    16501 ccgcggcacg acggcgcccc cgggtccgta cctctgaggt acggacccgg gggcggttcg
    16561 gctacttgcc ggcggggccg gccgaggggg ccggggcccc cggggcggcg gccgggtccg
    16621 gggcctcctc gaagtcgacc ttgcccatgt ggcggttcat cgacttcatc agctgccaga
    16681 ccgcgagggc cagcaccgcg aagacgacga agccgaggac gccgggggtc accttgttct
    16741 cgtccagctc ttcggcggcg aaggggacaa gctgggtcag tgccaggtgt gcgctcatgt
    16801 caggcattgt cgcggatgcc cgcgaagaga tcttcctcgg ggagggaggt cggcaccagc
    16861 gccttgctga gctcgtactc ctccgtcggc cagacctcct tctggatgtc catcgggacc
    16921 cggaaccagc cgccgtcggg gtcgatctgg gtgcggtggg cgatcagggc cttgtcgcgg
    16981 atctcgaaga actccgcgca gggcacgtgg gtggtcagcg tccgctcctt gcccccgaac
    17041 tccttccagc gctccagcca ctcgccgtac ggggactcca ggccccgcgc gaggagcgcc
    17101 tcgtgcaggg cgaccgtgcg ggggcggttg aagccctggt tgtagtagag cttcaggggc
    17161 tgccagaccg ggccgaactc ggcctcgggg aacttctcgg cgtcggccgc gccgtcgaag
    17221 gccaccatcg agatcttgtg ggtcatgatg tggtcggggt gcgggtatcc gccgttctcg
    17281 tcgtaggtcg tgacgacctg cggacggaag gagcggatct tgcggaccag ttccccggcc
    17341 gcggtgtcga cgtcctccag ggcgaagcag ccctcgggga gcggcggcag cgggtcgccc
    17401 tcgggcaggc ccgagtcgac gaagcccagc cattcctggg agacgccgag gatctcgcgg
    17461 gcctcgtcca tctccttgcg gcgtacctcg tggatgttcg cctcgacata ggcgtcaccc
    17521 tggagctggg ggttcaggac cgagccgcgc tcgccgcccg tgcacgtcac gaccatgacg
    17581 tccaccccct cggacacgta cttggccatc gtggccgcac ccttgctcga ctcgtcgtcg
    17641 gggtgggcgt gaacggccat cagtcgcagc tgctcagtca agactcgatc ctcagtgatt
    17701 cgacgcggag cgtggtctct atagtgacgg aatcggggga gcgaaaattc cgccaccccc
    17761 ggcttcgaga ggatcgatca tgagcgcggt gcgagagcag ctgcccgagg ggcgctacgg
    17821 acgctccgcg gacgaggcgg ccgaccgcaa gctcaggatc accggcgccg tgctcggcgt
    17881 cctcttcctc ggactgatgg gctggttcgg ctggtactac gtcgtcgaca gcaagatcag
    17941 cgccgagatg atcaagttcg acgtggtgag cgccaccgag gtccaggtac acctggagat
    18001 ccgcaaggac gagggcgtca agggcgtctg caccctgcgc tcccgctccg aggacggcgc
    18061 cgaggtcgcc cgcaaggacg tccgggtcga cgagcccgcg ggccgggtcg accgcgtcta
    18121 ctcgctgcgc acgaccgccc gcgcgaccag tgcggagctc atggggtgta cggctcggta
    18181 gcggtgggta gggaccgggt gtcgagtccc ggcgcgtcac cccggtgacc tggggcgacg
    18241 ccatcttgat ggttatgtcc tcccgctttt cgccactcat tgttaggctc gtggtttcgc
    18301 ccacccggga cagcagagct ttcccgtgta gggcgatgct ttgtattccc agtacctacg
    18361 aggagcacct gtgacccaga ccagcgacaa cgtcacctgg ctcacccagg aggcgtacaa
    18421 caagctcaag gacgagcttg agtacctgtc tggtcccgcg cgcacggaga tcaccgtcaa
    18481 gatcgccgca gcccgcgaag agggggacct gcgcgagaac ggcgggtacc acgcggccaa
    18541 ggaggagcag ggcaagcagg agctccgcat ccggcagctg acccagctcc tcgagcacgc
    18601 caaggtcggc gaggctccgg cggacgacgg cgtcgtcgag ccgggcatgg tcgtcacgat
    18661 cgccttcgac ggcgacgaga acgacacgac gaccttcctg ctcgcctccc gcgagtacgc
    18721 gagcggcgac atcgagacct actcgccgca gtcgccgctc ggcgtcggtg tcaacggcaa
    18781 gaaggccggt gacgacgccg agtacgagct gccgaacggc aagaaggcca cggtgaagat
    18841 cctcagcgcg aagccgtaca acggctgagg cacagctctc cacgaagggc cggcccccac
    18901 cggggccggc ccttcgtgct gcgtacggcc ggcccccgtc ccgcacccac cgtccggtga
    18961 tgcgatgagg catgatgcgg cctgacgtcg cgtcacaagg gggatgacga agtgctggga
    19021 ccgctgcgcg cgggcacacc gcgcctgata ggaccgtacg aactgctcgc caggctcggg
    19081 gcgggcggga tgggcgaggt cttcctcggg cggggcggcg gcggcgcgga cggcacgttc
    19141 gtcgccgtga agaccgtccg gcgcgacgtc gcgggcgacc ccgccttccg cgaccgcttc
    19201 cgccgggaga tacgggtcgc cgcgctcgtg gacagcgcgt acgccgccgc cccgctcggc
    19261 ggtgacgccg acgccgaggt gccctggctg gccaccgcgt acgtccccgg gccgagtctc
    19321 tcgcaggccg tccggcgcgg cggcgcgctg cccgtggact ccgtccgcgc gctcggcacc
    19381 gccgtcgcac gggccctcgc cgatctgcac cgggccgggg tcctgcaccg ggacctcaag
    19441 cccggcaacg tcatgctctc cgtcgacggg ccccgtctca tcgacttcgg catcgcccgc
    19501 agcagcacgg ccaccacgat gaccgccacc ggtctgatgg tcggcacccc ttccttcatg
    19561 tcgcccgagc acgtggccgg cgcccggcgg gtgaccgccg cgtccgacgt cttctgcctc
    19621 ggctcgctgc tctgcttcgc ggcgaccggc gaggacccct tcggcgacgg tccgctcgcc
    19681 gccgtcctgt accgggtctc ccaggccgag gccgacctcg cccgggtccc ggcggagctg
    19741 cgcgacaccg tcgccgcctg tctggccctc gacccggcgg accggccgac gccggaggag
    19801 ctcgcggagc tcctcggcgg cggcacgccg aaggtcttcc cgtggcccgg ggcggtacgg
    19861 gaccacatcg gcgagtacgg cacggagctc gcccagctcg tcgcctccgg cgggccgctc
    19921 ctggaggccg ccccggcgga cccgggagac gcggcggcga accccgacgc acccggcctg
    19981 cactccgcgg cgacccgggc accggtctcc gcgccggccg cgaccggccc gaacggcacg
    20041 ggcgacccgg gcgacgcggc cggccgccgg cgccgggtcc ggctgctcgc ggccgccgtg
    20101 gccctggccg tcgtggccgg cggcgtcggc acgtacctgc tgtggccgga gggcgggccg
    20161 gggaagcctc agcccccgaa ggccgcgccg gtggcgcccc ggatcccggg cgtcgacggc
    20221 cggggcctcg ccgactcctc cggtgtggtc ccgcagaaca ccgcccagcg gccggccggc
    20281 tggaagccct ggcaggcgaa gctcggcgac ccggcgctcg gctgctcggc cggcgagaag
    20341 gtgctggtct gccggaccac gaacggacgc tacgtggcgc tggacccggc gagcggcaag
    20401 cagctgtggg acgtcccggc cgccaaggac acccccgacc agacctacat cagcggcaag
    20461 gggttcccct tcaccgccgg cagcgccacg gcccccatgg tccacgacgg cagcgtcgtc
    20521 ctcgtcgcga acggctccct ccaggtccgg gacgcgcgca ctggggcggt ccgctggcag
    20581 aagccggccg tcggcccgca gggcctctgg gccacccggc ccgtcgtcgc cgacgggatc
    20641 gtcttcgcgg cgacgaacgt gacggaggac gccctgaacg tgcgggccgc gctgacggcg
    20701 ttctccctgg ccgacggaga gacgatctgg tcggaggagc tcaccaacgg cgagacgtcc
    20761 ttcgccgagc gccgggcgta cgaacccgtc gcctacgcca agggcgtcgt ctacgccctc
    20821 agccagggcg gactcgtctc gtacgacggc cggaacggca cccagctcgg gcaggtcgaa
    20881 cccgacgcca aggactgctg ggacatcaag gtgctcggta cgtcggcgta ctgctccgga
    20941 gccggggcgg gcagcgacac cgacacggcc ctgcaccagc tcgacgcccg caccctcgcc
    21001 ccgaaggcgt cgctgcccgg cggcctcgcc acggcggctc ccacggcggt cggcccacgg
    21061 gccgtggtgg ccttcgacgg cggcctgcgg atcctcgacc cgcgcaccgg cgggacactc
    21121 gcctcgttcc cggccggccg ggctccggcc ggactggccc agagctggtc gtcgccgctg
    21181 ctcgccggcg accagatcgt ctacgccgac tactccgccc tccacacggt gcggctgggc
    21241 gccgacggca ggccggggga cctgaaggtc acgccgttgc cgggcgcccc cgggccgcgc
    21301 gccgaggagg aggactacga cccgagcttc gggaacatcg tcgccaggca gatccgggag
    21361 ccggaggtgc tgccggtggg cggcatcgcg tacgtcgtct tcgacaaggg cgcggtcgcc
    21421 tccgtcgccc tgcccggcga gaaggagtag tcccgtgctg gaagccctgc ccccgggccg
    21481 gcccgcgcag ctcgtcggcc cctaccggct cctcgcccgg ctcggcgccg gcggcatggg
    21541 cgaggtccat ctcgcctgcc gggcggacgc gccgacggcc gacccgtacc ggatggtcgc
    21601 ggtgaagacc gtacggagcg atctggaggt cgacggggac ttccggaccc ggttccggcg
    21661 ggagatcgcg gcggcccgga cggtcgacgg gccgggcgtg gcgcggctcg tcgacgcgga
    21721 cgccgacgcg gcctcgccgt ggctggcgac ggagtacgtg ccgggcccct cgctcgcgga
    21781 ggccgtcgta cggtccgggg cgctgcccgc cgcgacggtg cgggccctgg ggatcgccct
    21841 ggccaccgcc ctgtccggcg tccacggggc gaaggtgctg caccgcgacc tcaaaccggc
    21901 gaacgtcctg ctcggcacgg ccgggcccaa gctgatcgac ttcggcatcg cgcaggcctt
    21961 cgaggcgacg gcgctcacct cgaccggtct ggtcgtggga tcccccggtt tcatgtcgcc
    22021 ggagcacctg gcgggcagcc gcgcggtggt gcccgcgtcg gacgtgttct gtctgggcgc
    22081 ggtcctcgcg ttcgcggcga gcggccgggg gcccttccag gacgacgaga tggccgcggt
    22141 ggtctaccgg atcatccggg cggacgccga cctgaccggt gtcccggagg agctgcggcc
    22201 ggtggtggag cgctgcctgc ggctcgaccc ggccgagcgg ccgacggcgg cggagctggg
    22261 ggcgctcctc ggtgccggag cgggccccgg ggtcttcccc tggcccggcg gggtgctgtc
    22321 gctgctcgcc gagtacgggg aggcggcgcg gacggccggt gaggcggccg cctcgggcgc
    22381 gggcgtggcg gacctgccga cgctcgggcc ggtggtgccg tactccccga cggccgtccc
    22441 gaaccgtccg gcgaccccgc cggcggaccc cgtggcgccg cgccggcgcc gctggggcgc
    22501 ggccgtggcc ggtgcggtgg ccgtcgccgt cgcggccacg gccggtgtgg tcctggtgaa
    22561 ccgggacggc ggggacggcg gcgggacggc ggggccctcg gt
//
