LOCUS       NZ_LIVV01000001        20771 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02009 scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_LIVV01000001
VERSION     NZ_LIVV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02009
  ORGANISM  Streptomyces sp. CB02009
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1660693)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660693)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905825.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:41:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,214
            CDSs (total)                      :: 8,139
            Genes (coding)                    :: 7,984
            CDSs (with protein)               :: 7,984
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 51 of 155
            Pseudo Genes (incomplete)         :: 117 of 155
            Pseudo Genes (internal stop)      :: 15 of 155
            Pseudo Genes (multiple problems)  :: 26 of 155
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:06:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1206190
            Orig. end                         :: 1226961
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20771
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="8"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20771
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20771
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10771](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10771
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(771..1340)
                     /locus_tag="AMK27_RS05405"
                     /old_locus_tag="AMK27_05290"
     CDS             complement(771..1340)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521180.1"
                     /locus_tag="AMK27_RS05405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05290"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_073903982.1"
                     /transl_table=11
                     /translation="MNEIHAHLTSSAAEAARVTRGVTPEQLADPSGCTDWTVRELANHL
                     VLYTAHGLEHRALRTQLPDDLVARDFTADADWPEQYAAQLDRALAAWAKPEAWDGDIDL
                     GGGNTVPAGEIAAMLLAELALHGWDLARATGQDFSLPDDTGTYLLDVVERYAEMYREYE
                     GFASPTPVDPTAPAFTRAVATSGRTI"
     gene            complement(1620..2879)
                     /locus_tag="AMK27_RS05410"
                     /old_locus_tag="AMK27_05295"
     CDS             complement(1620..2879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057045.1"
                     /locus_tag="AMK27_RS05410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05295"
                     /product="saccharopine dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_073902908.1"
                     /transl_table=11
                     /translation="MRVLLVGAGGVGSAITKIAARRGFFDQFVVADYDLARAEAAVAAL
                     GSEETRFSACRVDASDEAAVTRLLTERGCDVLMNATDPRFVMPLFNAALAAGSHYLDMA
                     MSLSHPHPDEPHSVCGVKLGDEQFARAAEWEKSGRIALVGMGVEPGLSDVFARYAADEL
                     FDEIEEIGIRDGADLSVEGYDFAPSFNIWTTIEECLNPPVVYERERGWFTTAPFSEPEV
                     FDFPEGIGPVECVNVEHEEVLLIPRWVGARRVTFKYGLGEDFIDKLKTLHALGLDSTTP
                     VAVRGEDGNPVRVSPRDVVAACLPDPAALGDRMTGKTCAGTWVKGTKDGAPREVYLYHV
                     VDNQWSMREYGSQAVVWQTAVNPVVALELLATGAWSGPGVLGPEALPPRPFLDLLTAYG
                     SPWAVREQDPTTPGSTQAPA"
     gene            3004..3720
                     /locus_tag="AMK27_RS05415"
                     /old_locus_tag="AMK27_05300"
     CDS             3004..3720
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033232.1"
                     /locus_tag="AMK27_RS05415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05300"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073902911.1"
                     /transl_table=11
                     /translation="MAKEVVPEEARRRRRPTRQGTVLSERLIVETALRMVREHGSAGLS
                     ARRLGAALGADPSTLYRYFDGMDGLTRAIGEELIGRALAGWAATGQWREDLRSLGLRIH
                     GAYLAHPQAALLTASRVTGRPREITADEAILGSLRGAGFADGDAVWIYHAYIDQCLAFA
                     ALDAGALALTAKVRAADEEMWESTYARLPADAYPNIAATAGLLAERMPHSAYPVALDML
                     LESAERQLEAGGGVAT"
     gene            complement(3849..4790)
                     /gene="ppk2"
                     /locus_tag="AMK27_RS05420"
                     /old_locus_tag="AMK27_05305"
     CDS             complement(3849..4790)
                     /EC_number="2.7.4.1"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006793 - phosphorus metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ppk2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010046971.1"
                     /locus_tag="AMK27_RS05420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05305"
                     /product="polyphosphate kinase 2"
                     /protein_id="WP_073903984.1"
                     /transl_table=11
                     /translation="MLSGLSVDETNPEQPVLLSAEGAPIRTWRENYPYDRKLRRGEYER
                     DKRILQIELLKLQRWAKDTGARVVVVCEGRDAAGKGGTIRRFTERLNPRGARIVALDKP
                     TEREAGQWYFQRYVTHLPGPGEIVFFDRSWYNRAGVERVMGFCSDDEYALFLRQCPVFE
                     RMLVDDGIHLVKFWFSVSRSEQRTRFAIRQVDPVRQWKLSPTDLASLDRWDDYTTAKVD
                     MFRATDTAHAPWTVVKTNDKRRGRLEAMRSLLWRMDYVSKDPEAVGDPDPLVVGAADTL
                     LEAGEETSTLSPTPLTSHHHGPGAHPERNPDT"
     gene            5395..5688
                     /locus_tag="AMK27_RS05425"
                     /old_locus_tag="AMK27_05310"
     CDS             5395..5688
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK27_RS05425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK27_05310"
                     /product="hypothetical protein"
                     /protein_id="WP_073902913.1"
                     /transl_table=11
                     /translation="MSTQQGPDRTDRRHPTDRRYGPDEAAEAGEVLTRDPQNQQAEQGE
                     DPLAIPVPDWPDSVAPASAPAGTGGRGDAEPREPESSTESGSEAPDVDEPVD"
     gene            complement(5727..6500)
                     /locus_tag="AMK27_RS05430"
                     /old_locus_tag="AMK27_05315"
     CDS             complement(5727..6500)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268249.1"
                     /locus_tag="AMK27_RS05430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05315"
                     /product="restriction endonuclease"
                     /protein_id="WP_079188201.1"
                     /transl_table=11
                     /translation="MRATDVDRVAVRRDSRVWRDLVLAVGLVGIGVSGLTLFLKAAQTA
                     GSRGSGVVAAVLVVLGALGVLSVGLSTFKRDMPSLRLRGRGRRQDIRREYLIPAPAAPA
                     AHTVPDIRSEALDHTAVDPDGFEHTVAALCARDGCTPVEVVGGAGDLGADVIAVTVDGR
                     RVVIQCKQYAPDNHVGSQDLQRFGGTCFTIHEADVAVVVTTSSFTGPAAEYAATCGIIC
                     VDGEALDAWTNHTTPAPWDASDTEPTVPLPLGAQG"
     gene            6973..7617
                     /locus_tag="AMK27_RS05435"
                     /old_locus_tag="AMK27_05320"
     CDS             6973..7617
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238304.1"
                     /locus_tag="AMK27_RS05435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05320"
                     /product="GAP family protein"
                     /protein_id="WP_073902916.1"
                     /transl_table=11
                     /translation="MFLDLIVIGTAISLGPLHNSAFILLLSSRRGFRKGLAFLLSWLAN
                     LVAVIACVVLLTGGKPPAHNSAPSTVAIVAKLVIGVALVLYGLRRHRRPPAPHGPPRWA
                     ARIDDASLGTAAALAWLLQPWGLVGVGAATAVDADLSTLNDWLALSAYCLLATLSLVVM
                     EMYAVRAPEAATARLNALRSWLEQHQQQLIVGLSLAVGLWVTARSVYELIA"
     gene            complement(7901..8233)
                     /locus_tag="AMK27_RS42645"
                     /old_locus_tag="AMK27_05325"
     CDS             complement(7901..8233)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025563.4"
                     /locus_tag="AMK27_RS42645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05325"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_158076899.1"
                     /transl_table=11
                     /translation="MATGSCLDDSQQFGLRGYGCNGGVYQKWNVHVWGDGTRQLRNLAT
                     NECLFDDGFTLATHACNSTREQSWFAHKSGDRVTFQSQATGECLDDSQYGLRTIPCLYN
                     RNQTWR"
     gene            complement(8764..9786)
                     /locus_tag="AMK27_RS05445"
                     /old_locus_tag="AMK27_05330"
     CDS             complement(8764..9786)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019357618.1"
                     /locus_tag="AMK27_RS05445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05330"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_241847309.1"
                     /transl_table=11
                     /translation="MKRIHFTGQDLMRIRVAGTIGTAAETLDSLKLLHAAGVGLGFRRW
                     QVSVRGRLDEQVGPLLVLLPPQGPAVDLWSLAGDSVCIEEAVDRLLGASRELLRIEFEN
                     IRFPPAHRAWARNLVDGDREAWLQVAAALRACHGVAVAPYWGRVRSHLGEVRATYANAM
                     AEGGVDHLLNTLSGPMLRWRPPVLELDHPHEADVHLNGRGLVIAPTLFSVGHAELMHPM
                     LDPAAAPVLAVPTVTDVLVGSTLWDGGAASTGQALVELLGRTRAAILEALAVGRSTAAP
                     GRSTTDLARRLSIAPATVSHHTSVLRNSGLVTTRRDGKAVLHTVTSMGMALLDPGSHAL
                     "
     misc_feature    complement(9388..9390)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..10771
                     /locus_tag="AMK27_RS05450"
                     /old_locus_tag="AMK27_05335"
     CDS             10001..10771
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="AMK27_RS05450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05335"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_158076900.1"
                     /sec_met_domain="CDPS (E-value: 8.2e-19, bitscore: 64.6,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNPSPSPSPSLLPAPSLSSAPPERRRRTSYRATVESVSPLAHRD
                     TSDAHAACFLGVSLDNSSFSPARFDAMLTWVSHRYSRCTVLIGDSIHRLTLASTRGMDP
                     DRALAHALDLGQQFMRDRQPALDAHRARTEFTFVTCGEVQETPEYAEFHHELSTLFAKD
                     EDFRASVEAFGRAYHAKRSATVDDAELRRRIDTSSAYFLEEFAVFCCLTRRDLPVMVYP
                     GQFSTLAEIAAGRHPQAPDELRDLILVSLRVRGR"
     misc_feature    10121..10123
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11026..11039
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.84"
                     /tool="antismash"
     gene            11053..11601
                     /locus_tag="AMK27_RS05455"
                     /old_locus_tag="AMK27_05340"
     CDS             11053..11601
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264688.1"
                     /locus_tag="AMK27_RS05455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05340"
                     /product="DUF1062 domain-containing protein"
                     /protein_id="WP_073902925.1"
                     /transl_table=11
                     /translation="MLTTWVVMPTCLPAVLRRCHTCGAERCRANGKFRVNANHKLLDAW
                     LLVLCTSCGETAKLTVLERAHVRSVPPALLDRMHDNDPGLAAELLQDPVLRRRNRVALD
                     WDGAWRLDTGGTAHPDGEAVDVSVRFAARIPVRPVRLIADGFGLSRAEVGRLIAEGRIV
                     SADRLNGRLSGDFTFLHKP"
     gene            complement(11722..12930)
                     /locus_tag="AMK27_RS05460"
                     /old_locus_tag="AMK27_05345"
     CDS             complement(11722..12930)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557406.1"
                     /locus_tag="AMK27_RS05460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05345"
                     /product="hypothetical protein"
                     /protein_id="WP_073902928.1"
                     /transl_table=11
                     /translation="MRSIEDLIPRAGSDDTAGLREVDAQELARYVVDRGHPWWRRRPCV
                     IALTRRVPERYVPELIACVQDPRDTSEVRRSLLDLLADRTELLPWLRHEDRAADTSYGM
                     GEAFLKARGLLGDRTAARGLATLAASPQRSARDAGDAGLDGLVDRYGADAILAELGEGR
                     PEDREFHVWMRYRADEDVTDALADPDRRVAYVAHSLATDTDRLRAYLDEAPTTEAKVWA
                     AYALYGLTEDRAEARAVYDRLGRPRVEVEGLDEELRRVIVHAYGPGCERPSDPRWRLEA
                     VCADPPARPDVDDQLRRATAALAAAGLAPKPPVSCGEDNQQGDGTYHVIEVGGDRLLIS
                     TLGPFATAEEDAPDAARCALASAGFRWIDGETGAIRVTDLCVYSFGRRDSLTVDALLFF
                     WQD"
     gene            13017..13898
                     /locus_tag="AMK27_RS05465"
                     /old_locus_tag="AMK27_05350"
     CDS             13017..13898
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657825.1"
                     /locus_tag="AMK27_RS05465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05350"
                     /product="arginase family protein"
                     /protein_id="WP_073902931.1"
                     /transl_table=11
                     /translation="MTLPGERGLAVVDAPSVLGLRPSGVQELPDAVLGGVARVARVEPP
                     AYDPVRDAGTGVLNPGGIARYSVRLADVVGEVLDSGSFPVVLGGDCSILLGNLLALRRR
                     GRYGLLFLDGHTDFYRPSAEPTGEVASMELALATGRGPRRLADLEGLGPLVRDEDVVAF
                     GFRDADESAAAGSLPLPPRLYALALDDVRAAGAREAARGAVARLAEREGYWVHLDVDVL
                     DDAIMPAVDYRQPGGLSWAELEDVLRTVLGHERAAGFDVTIFNPRLDPSGTVAGRLTDC
                     LRRALAVEDPAV"
     gene            complement(14069..14692)
                     /locus_tag="AMK27_RS05470"
                     /old_locus_tag="AMK27_05355"
     CDS             complement(14069..14692)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK27_RS05470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK27_05355"
                     /product="hypothetical protein"
                     /protein_id="WP_073902934.1"
                     /transl_table=11
                     /translation="MHTATRPALVLTTALVLGLGLPQPAAAHGDNLDVVITGHRDGHVL
                     TEVTWENDGDPVDEQVAALVSAVSADGLRTAGPWKLVRGTRPTAWTTAEALPTGVWKVT
                     VAAGQPALGHSERQLTVAAAPSSPSTASTPGGTAATPARTPHSARVTSPAPKASPSPSK
                     TASAAESEDEQTWGPWLTTIGLAVASLAGAAAGIWIRRRRGGRR"
     gene            complement(14992..17079)
                     /locus_tag="AMK27_RS05475"
                     /old_locus_tag="AMK27_05360"
     CDS             complement(14992..17079)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891101.1"
                     /locus_tag="AMK27_RS05475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05360"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_241847310.1"
                     /transl_table=11
                     /translation="MTAAMAVAAVIAGGIAYGAGRADSERTPLARLETPVTTVADTAVP
                     AAAPARSVEPEPIEKKPDNQPAKGMVYDGLKVAPEGDRCAGVYATATGLCTHGPDAPPK
                     GVDIKKDTPPAVKSVAPASDPAKPAAPRPAPRTGQGPSQDAPAVDAKAPRTPAAASPSP
                     STAAPAATGTTTAAAGPAGQTVQCDGDGSTGNRVQVVYVHGPGRDRYSQYLASFRKWAA
                     DADLIYSASAEETGGVRHIRYVTAADCTPTVLNIELPDSALSEFSATNRALAAKGLDRR
                     DRKYMIFADAQVYCGIGTFAGDERPAQSNLSNFGPSYGRTDSGCWGGHTAAHELGHNLG
                     AVNNSAPNTSRGAHCTDEWDVMCYSDTPYYPQMRNVCTNRASENILDCNHDDYFHTSPR
                     PGSYLATHWNIADNQFLMRTKGGGTGPDPTPNPTPSPTSTPTRTPTPTPTPTPTPTPTP
                     TQTGPRPGAGPDVTVGQIQADSVVVSWPRVGGASWYQVLLDGRHLTWVQGTALRIYNLR
                     PGTSHTAAVSVRDGQGRDSGPGRATSFRTAGAGGTTTPGTRYLLSNGSTGLSAQLWGGR
                     SADGTVLVGAQSNGYEQQQWYFDDAGSGLVRVRSAASAKCLQPGGTPAPGMWVAQQPCA
                     AGSSAQQWRMTVADGAVTLTDRSGSYALTVSTRPYYGSWLLDLQRVDGRPAQIWTARRA
                     G"
     misc_feature    17163..17177
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.89"
                     /tool="antismash"
     misc_feature    17232..17245
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.11"
                     /tool="antismash"
     misc_feature    17232..17246
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.46"
                     /tool="antismash"
     misc_feature    complement(17293..17306)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.06"
                     /tool="antismash"
     misc_feature    complement(17362..17375)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.52"
                     /tool="antismash"
     misc_feature    17416..17430
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            17774..>18277
                     /locus_tag="AMK27_RS43450"
                     /pseudo=""
     CDS             17774..>18277
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="AMK27_RS43450"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRGPLLSLRGITKHFGGVVALDAVDLRVDRGQVLGLVGDSGAGK
                     STLVKAVSGVVPPDAGTIEWQGVPVELRRPVDARRLGIATVYQDPSLVDRLDVVANLYL
                     GRELRRFGVLRQIEMEKRTIALLERLAISLPGIRTPVKSLTLGQRQTVAIARALLDRPE
                     LVVLD"
     gene            <18506..19600
                     /locus_tag="AMK27_RS43455"
                     /old_locus_tag="AMK27_05365"
                     /pseudo=""
     CDS             <18506..19600
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389479.1"
                     /locus_tag="AMK27_RS43455"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_05365"
                     /product="ATP-binding SpoIIE family protein phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LAVTLQQSLLPRGLPAQDAVEAAHRYLPAQAGVGGDWFDVIPLSG
                     ARVALVVGDVVGHGLHAAATMGRLRTAVNNLAMLDLPPDELLTHLDEVVARIDDEQTAG
                     GREDAVIGATCLYAVYDPVTCRCQLARAGHLPAMLLSPDGTTDIPDTPVGPPLGLRGLP
                     FTTVEFDVPEGSQLVFYTDGLVESRTHDIDVGLERLRTVLSHPGRSPEETCRAVLRGML
                     PADSADDIALLVARTRALPGDRIAEWNVPPDPSAVSASRAAATAQLRRWGLDDLVLGTE
                     LILSELVTNAMRHGGSPIGVRLVYGRTLICQVADGSNTSPRVRLAADTDEGGRGLFLVG
                     QIAQRWGTRYTEAGKIIWTEQRLP"
     misc_feature    19778..19790
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
ORIGIN
        1 gttggcgcgg ctacaccccg atgtctggcc tggacctcgc cgacgggagc gtccggtgga
       61 cgacaccgtc ggccgtgacc tccgtacaaa ccctcgcatg ggccggtggg gtgctgaccg
      121 ggagcggccg cgaggccgtt ctcctcgatc cggccgacgg gagcgacctg gctcggtggc
      181 ggctgccgga cccgctcgcg gggcccgacg cgaaggcgtt cgtcccggtg gacgcggagc
      241 gggtggtggc gatctgcgag ggctcgtccc tggtgacgct cgggctcgac gccgacgagc
      301 ccacaccgct cgggtcctac gatccgttca gggcagtggg tcgcatccgc ggctcggtct
      361 ggatgctgcg gtccggcaat gggctcctcg ccgtggatcc cgcagacggg acgtcgacat
      421 ggtcggtcga ggaggaccgg cggatcgtgg ccgaccccct tccgtgcggc gacggtgtcc
      481 tggtggggga tgccaacggc ggcatccggc tgttggggct cgacggccgg accgtggaag
      541 ggtgctccct gcccggccga cggctggacg cgctggccgc cgccgacgac ggcgggctgt
      601 tctttgcggc gaaggggaca ttcggcgcct tcagcgttgg gccggaggcc cggctgtcga
      661 ccacgtccgc agcgggcgcc tgagccccct ccggccgtga ccccactccg tacgatccga
      721 gatccgagat ccgagaccct gggcacggtt tgtgcccggt gtggcggagg tcagatggtg
      781 cggccgctgg tcgcgacggc gcgagtgaag gcgggggcgg tggggtccac cggggtgggg
      841 gaggcgaagc cctcgtactc gcggtacatc tcggcgtagc gttccacgac gtcgaggagg
      901 tacgtgccgg tgtcgtccgg caggctgaag tcctggcccg tcgcacgggc caggtcccag
      961 ccgtgcaggg cgagttcggc gaggagcatg gcggcgatct cgccggcggg cacggtgttc
     1021 ccgccaccga ggtcgatgtc accgtcccat gcctcgggct tcgcccaggc ggcgagggcc
     1081 cggtcgagct gggctgcgta ctgctcgggc cagtcggcgt ccgctgtgaa gtcgcgtgcg
     1141 accaggtcgt cggggagctg cgtacgcagg gcgcggtgtt cgaggccgtg ggcggtgtag
     1201 aggaccaggt ggttggccag ctcgcggacg gtccagtcgg tgcagccgga ggggtcggcg
     1261 agctgctcgg gggtgacgcc gcgggtgacc cgggcggctt cggcggcgct gctggtgagg
     1321 tgtgcgtgga tctcgttcat gacgtccacg ctagggaccc cgtccgcgtc ggtcttgaac
     1381 tttcccgaca cgttcttgga gggggtctgc caattgcgcc gctgccgctt gcgccgccgt
     1441 cggtcgcacc gctgtcggtt gtgccgctcg cctgcgtacg ggatgggcgt ggtcgtcggg
     1501 gttgcgtggc cgggccgggg gctcaccccg gcgtcccccg gaccagccga cccgcgacgt
     1561 gaggccggct gcccgcttgc tgatcggcgc gcgggcaggc gcccgggtca gggggcgtgt
     1621 caggcgggtg cctgggtgct gccaggtgtg gtcgggtcct gttcgcgcac ggcccagggg
     1681 gagccgtacg cggtgaggag gtcgaggaag gggcgcggcg ggagggcttc cgggcccagg
     1741 acacccggcc ccgaccaggc gccggtggcg aggagttcga gggccaccac cgggttgacg
     1801 gcggtctgcc agacgacggc ctgggagccg tactcgcgca tcgaccactg gttgtcgacc
     1861 acgtggtaca agtacacctc gcgcggcgcg ccgtccttcg tgcccttgac ccaggtcccg
     1921 gcgcaggtct ttccggtcat ccggtccccg agtgccgcag ggtcgggcag gcaggcggcg
     1981 accacgtcgc ggggcgagac acggaccggg tttccgtcct cgccgcggac ggcgacgggc
     2041 gtggtcgagt cgaggcccag ggcgtgcagc gtcttgagct tgtcgatgaa gtcctcgccg
     2101 aggccgtact tgaaggtgac ccggcgcgcg ccgacccagc gcgggatcag gaggacctcc
     2161 tcgtgctcga cgttgacgca ctcgaccggg ccgatgccct cggggaagtc gaagacctca
     2221 ggctcgctga acggggcggt ggtgaaccag ccgcgctcgc gctcgtacac cacgggaggg
     2281 ttcaggcact cctcgatcgt cgtccagatg ttgaaggacg gtgcgaagtc gtagccctcg
     2341 acggagaggt cggcgccgtc gcggatgccg atctcctcga tctcgtcgaa gagctcgtcg
     2401 gcagcgtagc gggcgaagac gtccgagaga ccgggctcga cacccatgcc gacgagtgcg
     2461 atgcggcccg acttctccca ctcggcggcc cgtgcgaact gctcgtcgcc gagcttcacc
     2521 ccgcagacgc tgtgcggttc gtcggggtgc gggtgcgaga gggacatggc catgtcgagg
     2581 tagtggctgc ccgccgccag cgcggcgttg aacaggggca tcacgaaacg cggatcggtg
     2641 gcgttcatga ggacgtcgca tccgcgctcg gtgagcagcc gggtgaccgc cgcctcgtcg
     2701 gaggcgtcga cgcggcaggc gctgaaccgg gtctcctcgc tgcccagggc cgcgaccgcg
     2761 gcctcggccc ttgcgaggtc gtagtcggcg acgacgaact ggtcgaagaa gccgcggcgg
     2821 gcggcgatct tggtgatcgc gctcccgaca ccgccggcgc ccacaagcag aacacgcatg
     2881 gcacagtcct ttctcggtga ggcgggtgcc tctgggggct gatggaaccc ggtgctccga
     2941 gttaaggtca atgatgttgg cataaggcgg cagacccgga cggcgacacg gaagagcgtg
     3001 gcgatggcga aggaagtggt ccccgaggag gcccgcagac gacggcgccc cactcggcag
     3061 ggcacggtgc tctccgagcg gctcatagtc gagacggcac tgcggatggt gcgtgagcac
     3121 gggagcgccg gcctgtccgc acggcggctc ggcgccgcac tgggtgcgga ccccagcacc
     3181 ctgtaccggt atttcgacgg catggacggg ctcacccgcg ccatcggcga ggagctgatc
     3241 ggccgggcgc tggccggctg ggcggcgacg gggcagtggc gtgaggacct gcgctcactg
     3301 ggactgcgca tccacggcgc ctacctcgcc catccgcagg cggcgctgct gaccgcgagc
     3361 cgggtgaccg ggcggccgcg ggagatcacc gccgacgagg cgatcctcgg gagcctgcgc
     3421 ggcgcggggt tcgcggacgg ggacgcggtg tggatctacc acgcctacat cgatcagtgc
     3481 ctggccttcg cggcgctcga cgcgggagcc ctcgcgctca cggcgaaggt gcgcgcggcg
     3541 gacgaggaga tgtgggagtc gacgtacgcc cgactgccgg ccgacgcgta tccgaacatc
     3601 gcggccacgg cagggctgct ggccgagcgc atgccgcaca gtgcgtaccc ggtcgcgctg
     3661 gacatgctgc tggagagcgc cgaacgccag ctcgaagccg gcggcggcgt cgccacctga
     3721 gcggacctga ggccctgagg ccctgaggcc ctgaggcctc cggcgtgggc tgccggaagc
     3781 cgccggtcgg acagcccacg cgggaggtct caggtccgct cgtgggagac atgggagaaa
     3841 tacgcctcct acgtgtccgg gttcctctcc ggatgggccc ccgggccgtg atggtgcgag
     3901 gtcaggggcg tgggggagag ggtggaggtc tcctcaccgg cctcgaggag ggtgtccgcc
     3961 gcaccgacga cgagagggtc gggatccccc acggcctcgg gatccttgct cacgtagtcc
     4021 atgcgccaga ggaggctgcg catggcctcc agacgtccgc gccgcttgtc gttggtcttg
     4081 acgaccgtcc agggggcgtg cgccgtgtcc gtcgccctga acatgtcgac cttggcggtg
     4141 gtgtagtcgt cccagcggtc cagggacgcc agatcggtgg gggagagctt ccactgccgc
     4201 accgggtcga cctgccggat cgcgaaccgg gtgcgctgct ccgaccgcga caccgagaac
     4261 cagaacttca ccaggtggat gccgtcgtcg accagcatgc gctcgaacac cgggcactgg
     4321 cggaggaaca gcgcgtactc gtcgtccgag cagaacccca tcacccgctc gacacctgcc
     4381 cggttgtacc aggagcgatc gaagaagacg atctcgccgg ggccgggaag gtgggtgacg
     4441 taacgctgga agtaccactg cccggcttcc cgctccgtcg gcttgtccag agcgacgatc
     4501 cgggcgcccc gggggttcag ccgctcggtg aaccgccgga tggtgccgcc cttgccggcg
     4561 gcgtcgcggc cctcgcacac gacgaccacc cgcgcgccgg tgtccttggc ccaccgctgc
     4621 agcttcagca gctcgatctg caggatccgc ttgtcccgct cgtactcgcc tcgccgcagc
     4681 ttgcggtcgt aggggtagtt ctcccgccag gtacggatcg gggcgccctc ggcactgagg
     4741 agaacgggct gctcggggtt ggtctcgtcc acgctcaggc cgctgagcag atccgttcgg
     4801 tccgggtccg ggtctcggtc tcggtctcgg tctgggtctc ggtccgggtc cgggtctcgg
     4861 tcccgatctc ggtccggggc acggttcggg gccctgtctc tgtcctggct ctcgccgtga
     4921 ccctcgttcc ggtcaccggc gccgctgatt cctgtcacac cattcacctc atcgccgtgt
     4981 cctcagctgc aggcccgccc cttcaccagg accggaactc ttcacagcgc tcctgccccg
     5041 atcatggagg accatcggcc gaggtcatgg tgttcgtaga gcctccgccg cgagtccacc
     5101 cggtcgtcgg tggagaagga cgctgcggca cgaagatcgc gagctggatg acgacccgga
     5161 ctacgagtct gatctacgag ccggatcgcg agccgggtgg tgaacgggtg gtctgctggt
     5221 gacggggtag tcgcgtaagc ggacgctgct ccctccgggg tctacggacc aatggggcct
     5281 ccgggcttcc ggctgcctgg gcctccggga cggtgagtgc acacgtccca gagaccatgg
     5341 cggcttcgtc aggcagggag ccgccaccag aatccacccg aggagtgagc tcgtatgagt
     5401 actcagcagg ggcccgaccg gacggaccgg cgccatccga ccgacaggcg ttacgggccg
     5461 gacgaggcgg cggaagcggg cgaggtgctc acccgcgacc cgcagaacca gcaggcggag
     5521 cagggggagg atcctctggc gatacccgta ccggactggc cggactccgt ggcgccggca
     5581 tccgccccgg ccggaaccgg aggccgaggc gacgcagaac caagggagcc agagtcgagc
     5641 accgagtcag gcagcgaggc ccccgacgtc gatgaaccgg tggactgagt gaagtgagtg
     5701 gacggaagcg atccgccagt ttcccctcac ccctgggcgc ccagggggag ggggaccgtc
     5761 ggctccgtgt cggacgcgtc ccacggggcg ggcgtggtgt ggttcgtcca tgcgtccagc
     5821 gcctcgccgt ccacgcagat gatcccgcac gtggcggcgt actcggcggc aggcccggtg
     5881 aaggagctcg tggtcacgac gacggccacg tccgcctcgt ggatggtgaa gcaggtgccg
     5941 ccgaaccgct gcaggtcctg ggatccgacg tggttgtccg gtgcgtactg cttgcactgg
     6001 atgacgaccc gccggccgtc gacggtgacc gcgatgacat cggcgcccag atcccccgcc
     6061 ccgcccacca cttccacggg ggtacagccg tccctcgcgc acagcgcggc caccgtgtgc
     6121 tcgaagccgt cagggtccac cgctgtgtgg tccaaggcct cgctgcggat gtcgggaacg
     6181 gtgtgagcgg cgggggcggc gggggcaggg atcaggtact cccgccggat gtcctgcctg
     6241 cgcccgcgcc cgcgcaggcg aagggacggc atgtcccttt tgaaggtcga cagtccgacg
     6301 gacagtacgc cgagtgcgcc gagcaccacg aggaccgccg cgacgacccc cgagccgcgg
     6361 cttcccgccg tctgggcggc tttgaggaag agcgtcagac cggagacacc tatccccacg
     6421 agccccacag ccagcaccag atcgcgccag accctggagt cccttctgac cgcaaccctg
     6481 tcgacatcgg tcgccctcat cccaacccct cccaccctca cgtgtcgacc gaccgtctgt
     6541 ccgcgcgcga ggcctcgaaa cgtggctgcc gaagtgatcg ttgtggcgtg cgtctccgga
     6601 catctgcgca cgtctgtgca tgtctccgtg cgtttcggtg cgtctctggc cggcccgacg
     6661 tacggccgac gtacgggctg acgcccgact gacgcccgac tgacggccga ctgacccccg
     6721 gctgacccag ggctgaggta cggcgctcgg ccggggcgtg ggtgaaggtg ctgcgtcgcc
     6781 tcggcgaccg cggcgtgccc ggggctcggg cgaaggtggg tgacgtgcgg gcgtggcctc
     6841 cttgaccggt ccctccgcca cctgcagagt cgggatgcgg cacccgtacc agcgccgccc
     6901 cctctgccgg ccggtccgta cgtcctgcgg tccgccggca caccaccctc acgtccggga
     6961 gcggctgatt cgatgttcct cgacctgatt gtgatcggta cggccatcag cctggggccc
     7021 ctgcacaaca gcgccttcat tctcctgctc tcctcgcggc gcggctttcg caagggcctg
     7081 gccttcctgt tgtcgtggtt ggccaacctc gtcgcggtga tcgcctgtgt ggtgctgctg
     7141 accggtggca agcctcccgc gcacaacagc gcgccctcga ccgtcgcgat cgtcgcgaaa
     7201 ctcgtcatcg gcgtggcact cgtgctgtac ggcctgcgcc ggcaccgccg accgcccgct
     7261 ccgcacggcc cgccgcgctg ggccgcccgg atcgacgacg cctccctggg caccgcggcc
     7321 gcccttgcct ggctgctcca gccgtggggg ctggtcggcg tgggggccgc gaccgccgtc
     7381 gacgccgacc tctccaccct caacgactgg ctggccctga gcgcctactg cctcctggcc
     7441 acgctcagcc ttgtcgtgat ggagatgtac gcggtccggg cgcccgaagc ggcgaccgcc
     7501 cggctcaacg ccctgcggag ctggctggag cagcaccagc agcagctgat cgtcggtttg
     7561 tccctggccg tcggcctgtg ggtgacggcc aggagcgtct acgaactgat cgcttgacac
     7621 gtacggccgc ggcgcgaccg ttcgccgggg ccgaccgggg ccgaccgggg ccgaccgggg
     7681 ccgaccgggg ccgaccgggg ccgaccgggg ccgaccgggg ccgaccgggg ccgaccgggg
     7741 ccgaccgggg ccgaccgggg ccgaccgggc ccgaccgggt gcgaccgacg cggcccggcc
     7801 tggcgaaccg gccgcacctg ccgcacaccc gaccccgccc ggccaggtcc tgtccccgac
     7861 ccccgtgggg acaggattcc cggccgggcg ggtcaccgca tcagcgccag gtctggttgc
     7921 ggttgtacaa gcacgggatc gtccgcagcc cgtactggct gtcgtccagg cactcgcctg
     7981 tggcctggct ctggaaggtc acccggtcgc cgctcttgtg cgcgaaccag ctctgctcgc
     8041 gcgtcgagtt gcaggcgtgg gtcgcgagcg tgaagccgtc gtcgaagagg cactcgttgg
     8101 tcgcgaggtt ccggagctga cgggtgccgt caccccacac gtgcacgttc cacttctggt
     8161 agacgccccc gttgcagccg tagccgcgca ggccgaactg ctgactgtcg tcgaggcacg
     8221 acccggtggc catgttcgcg aacgtctgca ccacgtcggc tgcgcgcagg gcgccgacag
     8281 cagtccctgt cgtttgctgg gcagaggcgg tggcgacctt tccggtgtgg gcggacggct
     8341 gggttcgcgg ctgcgccgac accgccgtgg acccgacggc caggagtcct gccgcggtca
     8401 gaagcgcgag tgtccccctg cggaaggaac gtgagaagga atgaggggag gagcgcggga
     8461 gggggcgcgg tgaggaatgc gtacgcatct ctttcgtcct ttcatcaatg ccaccgcgaa
     8521 cgaacgaacg tcgaacgagc gacgagcgaa cggcgtcggc ggcccttcgt caaccaggct
     8581 ctgcagcacg ccggtcgact cctggcgtgg ccggttgact cgcgctcacc gtaggttcga
     8641 gatcggtggc ggggccaagc attcgagctc cgtcgaaacc atgggaagag tcccgtggag
     8701 cccgccgaga gtttgtctat aggtcgtccg caatcggtcc gtagttcgtc cgcgggcgct
     8761 cggtcacagc gcgtgcgagc ccggatccag cagagccatg cccatcgagg tcacggtgtg
     8821 gaggaccgcc ttgccgtccc tacgggtcgt gaccaggccg gagttacgga gcacggacgt
     8881 gtggtggctc accgtcgccg gcgcgatgct gagccgacgc gccagatccg tggtgctgcg
     8941 gcccggagcc gcggtgctgc ggccgacggc cagcgcctcc aggatcgcgg cgcgtgtacg
     9001 tcccagcagc tccaccagcg cttgaccggt ggacgcggcg ccgccgtccc acagcgtgct
     9061 gcccaccagg acatcggtga cggtcgggac ggcgaggacg ggggcagcgg ccggatccag
     9121 catggggtgc atcagctcgg cgtgcccgac ggagaacaac gtgggggcga tgacgagacc
     9181 gcgcccgttc aagtggacgt ccgcctcgtg cggatggtcc agttcgagga ccggtggccg
     9241 ccagcgcagc atcgggccgg agagcgtgtt caacaggtgg tcgactccgc cttcggccat
     9301 cgcgttcgca tacgtcgcgc ggacctcgcc cagatgcgag cgcaccctgc cccagtacgg
     9361 agcgaccgcc acgccgtggc aggcccgtaa ggccgcggcg acctggagcc acgcttcgcg
     9421 gtccccgtcc accaggttgc gtgcccaggc gcggtgcgcg ggagggaagc ggatgttctc
     9481 gaactcgatg cgcagcagtt cccgggacgc gccgaggagc cggtccaccg cctcctcgat
     9541 gcacaccgag tcgccggcca ggctccatag gtcgacagcg gggccctggg gcggcaacag
     9601 gaccaggagc gggcccactt gttcgtccag gcgtcctcgg accgatacct gccagcgccg
     9661 gaatccgagg ccgacgccgg cggcgtgcag cagcttcaga ctgtcgagcg tctcggctgc
     9721 cgtgccgatc gtcccggcca ctcggatccg catcagatcc tggcccgtga agtgaatccg
     9781 cttcaccgag cattccgttt ccgcgttccc gttcgcacac atcagtcttg tgtgcgggcc
     9841 gatggccgca caacggccaa tcaggccaga cagcacgcga agctgcggat ggccgacggg
     9901 ccgcctgccg ttccgaaggc tgaggcaacg tttctgcagt cggtggcatc agacagggcg
     9961 accatccgtg cccagcgatc ccttcaggcg gaagaccacc gtggacaatc cctccccctc
    10021 accctccccc tcccttctcc ctgctccctc cctctcctcc gcacccccgg agagaaggcg
    10081 ccggaccagc taccgggcca ccgtcgaatc cgtctccccc ttagcccacc gcgacacctc
    10141 cgacgcgcac gcagcgtgct tcctcggcgt cagcctggac aacagcagct tcagccccgc
    10201 caggttcgac gccatgctca cctgggtctc gcaccgttac agccgctgca ccgtgctgat
    10261 cggcgacagc atccaccgcc tcaccctggc ctcgacccgc ggcatggacc cggaccgggc
    10321 cctcgcgcac gccctcgacc tggggcagca gttcatgcgc gaccggcagc ccgccctgga
    10381 cgcccaccgg gcgcggaccg agttcacctt cgtcacctgc ggcgaggtcc aggagacccc
    10441 ggagtacgcc gagttccacc acgagctgtc cacgctgttc gccaaggacg aggacttccg
    10501 cgcctcggtg gaggccttcg gccgcgccta tcacgccaag cggtccgcca cggtcgacga
    10561 cgcggaactc cggcgacgca tcgacacctc cagcgcctat ttcctggagg agttcgccgt
    10621 cttctgctgc ctcacccgcc gagacctgcc ggtcatggtc tacccagggc agttcagcac
    10681 cctcgccgag atcgccgccg ggcgccatcc ccaggccccc gacgaactcc gcgacctgat
    10741 tctcgtctcc ctccgggtac gaggccggta gcccgccgcc tcgcactccg cgtacgaggc
    10801 cggtagcccg ccgcctcgtc tccctccgcc ggtacggggg cgggcagccc gccccccgta
    10861 ccggtcccgc gcgaaaacct gtggaacggc ggcaccgtgc gcccgtacgg tgctgccgag
    10921 tcccgtcgtc gaaccaaggg caggccgttg tacaccgttt gagattcccc gagcgctgaa
    10981 ccgtcgcgcg tcgcgccctg cgcgccgtgc tccttcttgc tgcggatttc tcactgaaac
    11041 cggtgtactc ctgtgctcac cacctgggtg gtcatgccca cctgccttcc tgcggtcctt
    11101 cgccgttgcc acacctgcgg agccgaacgc tgccgggcga acggcaagtt ccgcgtcaac
    11161 gccaaccaca aactgctcga cgcctggctc ctcgtgctct gcacctcctg cggggagacg
    11221 gcgaaactca cggtcctgga gcgggcccac gtccgctccg taccgcccgc gctgctcgac
    11281 cggatgcacg acaacgaccc cggtctggca gcagagttgc tccaggatcc ggtgctacgg
    11341 cgccgcaacc gcgtcgccct cgactgggac ggcgcctggc gcctggacac cggcggaacc
    11401 gctcacccgg acggcgaggc ggtcgacgtc tcggtccgct tcgccgcccg gattcccgta
    11461 cggccggtcc ggctgatcgc cgacggcttc ggtctgtcgc gggccgaggt cgggagactg
    11521 atcgcggagg gcaggatcgt ctcggcggac cggctgaacg gccggctctc gggcgacttc
    11581 accttcctgc acaagccctg agccgtccac ggatgaaggg gttgtccggc ggcaccggcc
    11641 gccggacaac cccgggccca ccccgtggtc ttctcctgcc ggtgaagacc acccctggtc
    11701 ctgccagggg aagaccaccc tctagtcctg ccagaagaac agcagcgcgt cgaccgtgag
    11761 ggagtcgcgt cgaccgaagg agtagacgca gaggtccgtc acccggatcg cccccgtctc
    11821 cccgtcgatc cagcggaagc ccgccgatgc gagcgcacac cgggcagcgt ccggagcgtc
    11881 ctcctcggcg gtcgcgaacg gcccgagggt gctgatcagc agccggtccc cgccgacctc
    11941 gatcacgtgg tacgtcccgt ccccctgctg gttgtcctcg ccgcatgaga ccggcggttt
    12001 cggcgccagt ccggccgccg cgagggcggc cgtcgcccgg cggagctggt cgtccacgtc
    12061 aggccgggcg ggcggatcgg cgcagacggc ctcgagccgc caccgcgggt cgctcgggcg
    12121 ctcgcagccg ggaccgtacg cgtggacgat cacccgccgg agctcctcgt ccaggccctc
    12181 gacctcgacc cgggggcgcc ccagccggtc gtagaccgcc ctggcctcgg cccggtcctc
    12241 ggtgaggccg tacagcgcgt acgccgccca gaccttcgcc tcggtggtcg gcgcctcgtc
    12301 gaggtaggcg cgcagacggt ccgtgtcggt cgcgagcgag tgggcgacgt acgcgacccg
    12361 ccggtccggg tccgcgagcg cgtcggtcac gtcctcgtcg gcgcggtacc gcatccagac
    12421 gtggaactcc cggtcctcgg ggcgcccctc gccgagttcg gccaggatcg cgtccgctcc
    12481 gtaccggtcc acgaggccgt ccagaccggc atcacccgcg tcgcgcgcgc tccgctgcgg
    12541 cgaggcggcg agcgtcgcca gtccgcgcgc ggccgtgcgg tcgccgagca ggccacgcgc
    12601 cttcaggaag gcctcgccca tgccgtacga ggtgtcggcc gcgcgatcct cgtgccgcag
    12661 ccagggcagc agctcggtcc ggtcggcgag caggtcgagg agggacctgc gcacctcgga
    12721 ggtgtcccgg gggtcctgga cgcacgcgat cagctcgggg acgtaccgct cggggacgcg
    12781 gcgggtcagc gcgatcacgc acggccggcg gcgccaccac gggtgcccgc ggtccaccac
    12841 gtaccgggcg agttcctgcg cgtcgacctc ccgcaggcct gcggtgtcgt cggatccggc
    12901 ccgcggtatc aggtcctcga tgcttcgcat ccggggatgc tactgcccgg gcaaggccct
    12961 gagcaggcct gttccaccgg cgcgcgcggt ctgcccgacg gggacaccat ggacgtatga
    13021 cgctgcccgg cgagcgtggc cttgccgtcg tcgatgcgcc gtccgtactc ggactgcggc
    13081 cgtccggggt gcaggagctg ccggacgccg tgctcggcgg agtggcgcgg gtcgcgcggg
    13141 tcgaaccgcc cgcgtacgac ccggtgcggg acgccgggac aggggtgctc aacccaggtg
    13201 ggatcgcgcg gtactccgtg cggctggcgg atgtcgtcgg cgaggtgctc gactccggga
    13261 gctttcccgt cgtcctgggc ggcgactgca gcatcctgct cgggaacctg ctcgccctgc
    13321 ggcgcagggg ccggtacggg ctgctgttcc tcgacggcca cacggacttc taccggccgt
    13381 ccgccgagcc caccggcgag gtcgcgtcca tggaactcgc cctggccacg gggcgcggcc
    13441 cccggcggct cgccgatctg gaggggctgg ggccgctggt gcgggacgag gacgtcgtcg
    13501 ccttcggttt ccgggacgcc gacgagtccg ccgccgcggg gagcctgccg cttccgccgc
    13561 ggctgtacgc cctcgcgctc gacgacgtgc gcgcggccgg cgcgcgggag gccgcgcgcg
    13621 gcgccgtagc ccgccttgcc gagcgggagg ggtactgggt ccacctcgac gtcgacgtcc
    13681 tggacgacgc gatcatgccc gccgtggact accggcagcc cggcgggctg agctgggccg
    13741 agttggagga cgtcctgagg acggtgctgg gccacgagcg ggccgccggg ttcgacgtca
    13801 cgatcttcaa cccgcggctc gacccctccg ggacggtcgc gggccgtctg accgactgct
    13861 tgcgacgcgc cttggcggtc gaggacccag cggtgtagcg cggcggtcgt ccgcggcggt
    13921 gtcggctggg gcccttcgac ggcccccgcg tcgatccggg gtccgaccgg gggcccgtcg
    13981 ccccagggcc cgaccggggg tccgtcgccc ggggcccggt cgcggacttg cggcggaccg
    14041 gtgcgagccg gggcgcgtgc tgtcgccgtc agcgtcggcc tcccctcctg cgccggatcc
    14101 agattcccgc ggcggctccg gccagtgagg cgaccgcgag cccgatcgtg gtcagccagg
    14161 gaccccaggt ctgctcgtcc tcgctctcgg ccgcgctggc ggtcttcgac ggggacgggg
    14221 acgccttcgg agccggcgac gtcacccgcg cgctgtgagg agtgcgggcc ggcgtggccg
    14281 cggtgccgcc cggagtcgac gcggtactgg gtgacgaggg ggccgccgcc accgtcaact
    14341 gccgttcgga gtgcccgagt gcgggctgtc cggccgcgac cgtgaccttc cagacgccgg
    14401 tcggcagggc ttcggcggtg gtccaggcgg tgggtcgggt gccgcggacg agcttccagg
    14461 ggccggccgt gcggaggccg tccgcgctga cggcactgac cagcgcggcg acctgctcgt
    14521 cgacgggatc gccgtcgttc tcccaggtca cctcggtcag gacgtggccg tcccggtgac
    14581 cggtgatgac gacgtcgagg ttgtcgccgt gtgcggcggc gggctgcggc aggccgaggc
    14641 cgaggacgag cgctgtggtg aggacgagtg cggggcgggt ggcggtgtgc atggcggtgc
    14701 tccggtccgg tacgggaggg atggcgtggg ccttcccggc tggggctgac gagtcgtgtc
    14761 ccgagcggtg cgcgcggttc gcggggatgg cggttcgcga gggcgagggt tcgagccggt
    14821 ggtggtacgc cagggggagg gtgttcctag cggcgagggt tcgcgcgggt gatggtgcgc
    14881 gggggcgggc tttcgtggcg gtggtggtac gcaagggcga gggttcgcga gggcgggccg
    14941 ccgttcggcg gcccgcccca ggtgcgacgc ggacgggacc cgcgggccgg ttcagccggc
    15001 ccggcgggcc gtccagatct gcgccggccg gccgtccacg cgctggaggt cgagcaacca
    15061 ggacccgtag tacgggcggg tgctgacggt cagtgcgtag gagccgctcc ggtcggtgag
    15121 ggtcacggcg ccgtccgcga ccgtcatccg ccactgctgg gcggaggagc cggccgcgca
    15181 gggctgctgg gccacccaca tgcccggggc gggcgtgccg ccgggctgca ggcacttggc
    15241 tgaggccgcc gaccggacgc gtacgagacc gctgcccgcg tcgtcgaagt accactgctg
    15301 ctgctcgtaa ccgttgctct gagcaccgac cagtaccgtg ccgtcggcgc tccggccgcc
    15361 ccacagctgg gcgctcagtc cggtgctgcc gttggagagc agatagcggg tgccgggggt
    15421 ggtggtgccg cccgctccgg cggtacggaa gctcgtcgcc cggcccggtc cgctgtcacg
    15481 gccctggccg tcgcggacgg agacggcggc ggtgtgcgag gtgccaggcc gtaggttgta
    15541 gatccgcagc gcggtgccct gcacccaggt caggtgcctg ccgtcgagga gcacctggta
    15601 ccaggacgct ccgccgaccc ggggccagct caccacgacg gagtccgcct ggatctggcc
    15661 gacggtcacg tcaggcccgg cgcctggccg cggcccggtc tgcgtggggg tcggcgtcgg
    15721 tgtcggcgtg ggcgtcggcg tgggcgtcgg cgtccgggta ggagtggatg tcgggctggg
    15781 tgtggggttc ggcgtcgggt ccggtccggt gccgccgccc ttggtccgca tgaggaactg
    15841 gttgtcggcg atgttccagt gcgtggcgag gtagctgccc ggccgtggac tggtgtggaa
    15901 gtagtcgtcg tggttgcagt cgaggatgtt ctcggaggcc cggttggtgc agacgttgcg
    15961 catctgcggg tagtacgggg tgtccgagta gcacatcacg tcccactcgt ccgtacagtg
    16021 cgcgccccgg ctggtgttgg gcgcgctgtt gttgaccgca ccgaggttgt gacccagttc
    16081 gtgggccgcg gtgtgtccgc cccagcagcc gctgtcggta cgcccgtacg aggggccgaa
    16141 gttgctcagg ttggactggg ccggccgttc gtcccccgcg aaggtgccga tgccgcagta
    16201 cacctgcgcg tcggcgaaga tcatgtactt gcggtcgcgt cggtcgaggc ccttggcggc
    16261 gagcgcgcgg ttggtggcgc tgaactccga cagcgcggag tcgggcagtt cgatgttgag
    16321 gaccgtgggt gtgcagtccg ctgccgtcac gtaccggatg tggcggacgc cgccggtctc
    16381 ctcggcgctg gccgagtaga tgaggtcggc gtcggcggcc cacttgcgga aggaggcgag
    16441 gtactgggag taccggtcgc gtcccgggcc gtggacgtac acgacctgga cccggttgcc
    16501 ggtgctgccg tcgccgtcgc actggacggt ctgcccggcg ggcccggcgg cggccgtggt
    16561 ggtcccggtg gctgccggag cggcggtgga gggactcggt gacgcggcgg ccggcgtacg
    16621 cggtgccttc gcgtcgacgg cgggcgcgtc ctgcgaaggg ccctggccgg tacggggcgc
    16681 gggccgcggt gccgccggtt tcgcgggatc gctcgcgggt gccacggact tgacggccgg
    16741 gggagtgtcc ttcttgatgt cgacgccctt gggcggcgcg tcggggccgt gggtgcacag
    16801 cccggtggcc gtggcgtaga cgcccgcgca gcggtctccc tcaggggcca ccttgagccc
    16861 gtcgtacacc atgcccttgg ccggctggtt gtccggcttc ttctcgatgg gctcgggctc
    16921 cacgctcctg gccggcgcgg cggcgggaac ggcggtgtcg gcgacggtgg tgacgggggt
    16981 ctcgaggcgg gcgagcggag tcctctccga gtccgcccgt cccgccccgt aggcgatccc
    17041 gccggctatg acggccgcga cggccatcgc ggcggtcacg ccgatgaagg gtctgcgggg
    17101 ccgtgcccgg cgggtacgac tgtccttcgg cttcctatgt ctaggcatgc acacctcaac
    17161 tctttggtca gaagactggg tgcgcggaag cctgtcagaa ccttcccgtg gagaattggg
    17221 acaaagggga gagtgttcaa ataatccatt ccgttaccta cgcctccgta tctgatgaac
    17281 actcaactgg ctttagaata aagctagttg aggaaaagct gacgccttgg tccaggcctt
    17341 tcaggtgctc ccgttatgcg attgaaataa ttcctgatgg ttattgacgc gaattcagtg
    17401 aaggattcat ctaatttctc acctcgtgaa tcccttcgat caccacccgt gagcacgcct
    17461 gcgggccgag cccgctttcc ggcccggcgc gtcggctgcg agacggtcct gacgcctcct
    17521 gacgccgccg gaaggtcccg ccctcgtcgg cggcggcccg ggcgcgccga agagcggggg
    17581 cgttcctgga cggtgggacg agtccgcggg aacgtgccgc cgaacggggc gttctcgcgt
    17641 gtcccgtctc caccgttcac cgggcgggca ccggagtgga caacccttgc cgaaggttcc
    17701 tcggaaggcc cgcccggtcg ggcggcggac cgggtgccgt ccgacgggcc gcggagaggg
    17761 tggaggtggg cgagtgccca gggggccgct cctgtccctg cgcgggatca ccaagcactt
    17821 cggtggcgtc gtcgctctcg acgcggtcga cctccgggtg gaccggggac aggtgctcgg
    17881 tctggtgggt gacagcggag cgggcaagag cactctggtg aaggcggttt ccggtgtcgt
    17941 cccgccggat gcggggacca tcgagtggca gggcgtcccg gtcgagctgc gccgacccgt
    18001 cgacgcccga cgcctcggca tcgccaccgt ctaccaggac ccgtcgctcg tcgaccgcct
    18061 ggacgtggtc gccaatctct acctcggccg cgaactgcgc aggttcgggg tcctgcggca
    18121 gatcgagatg gagaagcgga ccatcgccct gctcgaacgc ctcgccatca gcctccccgg
    18181 catccgcacc cccgtgaagt cgctcaccct gggccagcgt cagaccgtgg ccatcgcacg
    18241 tgcgctgctg gacaggcccg aactggtcgt cctggacgag ccgaccgcca cgctcacggt
    18301 gggacagacc tcgcggatgc tcgacctgat ccgcctgctg cgggaccagg gccacgcggt
    18361 gatcatggtc agccacaacc tcgacgacgt gcaggccgtc gccgaccgca tcgccgtgct
    18421 ccgcctgggc tgcaacgggg gtgagttcga atcccggtac accagccagg aacagctcgc
    18481 ggccgccatc agcggcggcc atccactcgc ggtgacgctc cagcagagcc tcctgccacg
    18541 cgggctgccg gcgcaggacg ccgtcgaggc cgcccaccgg taccttcccg cacaggcggg
    18601 cgtgggcgga gactggttcg acgtgatccc gctgtccggc gcccgcgtcg cactcgtggt
    18661 cggcgacgtc gtcggacacg gcctgcacgc cgccgccacc atggggcggc tccgtaccgc
    18721 cgtgaacaac ctcgccatgc tcgatctgcc ccccgacgaa ctcctcaccc acctcgacga
    18781 ggtcgtcgcc cgcatcgacg acgagcagac cgccggcggc cgcgaggacg ccgtcatcgg
    18841 cgccacctgc ctctacgccg tctacgaccc ggtcacctgc cgctgccagc tcgcccgcgc
    18901 cgggcatctg ccggccatgc tgctgagccc cgacggcacc acggacatcc ccgatacgcc
    18961 ggtcggcccg ccactggggt tgcgcgggct gcctttcacc acggtcgagt tcgacgtccc
    19021 cgagggcagt cagctggtct tctacaccga cgggctggtg gagtcgcgga cccacgacat
    19081 cgacgtgggc ctggagcgcc tgcgcacggt cctgtcccac ccggggcgca gcccggagga
    19141 gacctgccgg gccgtgctca gggggatgct tcccgcggac tcggccgacg acatcgccct
    19201 gctggtcgcg cgtacccgcg cgttgcccgg cgacaggatc gccgagtgga acgtcccgcc
    19261 cgacccctcg gcggtgtccg ccagccgggc cgccgccacg gcccagctgc gccgctgggg
    19321 actcgacgac ctcgtcctcg gtacggagct gatcctgagc gaactggtca ccaacgccat
    19381 gcggcacggc ggcagcccga tcggcgtccg cctggtgtac gggcggacgc tgatctgcca
    19441 ggtcgccgac ggcagcaaca cctcgccgcg cgtacggctg gcggcggaca cggacgaggg
    19501 cggacgcggc ctcttcctgg tcggccagat cgcccagcgc tgggggacgc ggtacaccga
    19561 ggccgggaag atcatctgga ccgaacagcg cttgccctga cgcggtgaac cccgtacccg
    19621 gggaaacgcg gccggacacg gcgcccgggc gcacggcgga gtggggagga gcgcgaggag
    19681 gcatgcggga gcgcgagagc gcttccgggt cgaacacctg acgcccggcc gcctgcccga
    19741 aaggatgaac ggagcccgtc accggcgttt cgccccggtg ccgccgtcac cctgctgacg
    19801 tgcgcaagga gttcgagaac agggtcccgc cccagcggcc gtcccgtccc gccgccgtcc
    19861 cgggcccgcc tccccccggc ccgccccacc accggcacgt ggcatcgctg cgggaccgga
    19921 cgcagtactg ggtggaccgc accgtggtga agggcatgac cgcggcggcg ggctggctcg
    19981 cgctggtctg cctggctgtg gtggcaccgg cgagcgccct cctcgtctgg accgacaacc
    20041 gctcgcccga caccctccag ggcaaggtcg cgaccgtctg gcggaccgtc ggccagacac
    20101 tccggatcgg cggcgaggtc ggcccgccgc tgcggatggt cctctccgtc ctgctggccc
    20161 tcgtctccct cctctacgtc tcgactctcg tcggcctcgt caccaccgcg atcaccgacc
    20221 ggctgaccga gctccagcgc ggccagtcga cggtcgtgga gcgcggccac tcactggtcc
    20281 tcggctggtc cgagcagacc ccgacgctcg tcgccgagct gctcgccgcg catgcccagc
    20341 ggcggaacag cgcggtcgtg gtcctcgccg accgcgacaa gctcgacatg gagcgggagt
    20401 tgcgggcggt tctcgccgcc gccggcgtcc gacgcgtccg gctcctctgc cgacgcggcc
    20461 gccccgccga cccggcggct ctcgcccgcg tcagcccggc cgccgcagga gcggtcgtgg
    20521 tgctgccgcc ggacaccccc gaggccgaca cccaggtcgt caagacgctg ctcgcgctac
    20581 gggccgtggt cggcgacacg aggccggtac gggtcgtggc ggcggtccgg cagacccagc
    20641 acgtcgccac cgcgcggctc gccgccgggc ccggcgcggt cgtcctcgac gtcgacggca
    20701 tcgcggcccg gaccctcgtc cagtgcgtca tcgaacccgg cctgtcgctg gtcctggagg
    20761 acctgctcga c
//
