LOCUS       NZ_LIVV01000001        22199 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02009 scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_LIVV01000001
VERSION     NZ_LIVV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02009
  ORGANISM  Streptomyces sp. CB02009
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1660693)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660693)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905825.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:41:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,214
            CDSs (total)                      :: 8,139
            Genes (coding)                    :: 7,984
            CDSs (with protein)               :: 7,984
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 51 of 155
            Pseudo Genes (incomplete)         :: 117 of 155
            Pseudo Genes (internal stop)      :: 15 of 155
            Pseudo Genes (multiple problems)  :: 26 of 155
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:06:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 707685
            Orig. end                         :: 729884
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22199
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22199
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22199
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12199](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12199)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    123..137
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(875..889)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.63"
                     /tool="antismash"
     misc_feature    complement(879..894)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     gene            948..1757
                     /locus_tag="AMK27_RS03145"
                     /old_locus_tag="AMK27_03090"
     CDS             948..1757
                     /NRPS_PKS="Domain: ECH (12-261). E-value: 4.9e-54. Score:
                     175.1. Matches aSDomain:
                     nrpspksdomains_AMK27_RS03145_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057883.1"
                     /locus_tag="AMK27_RS03145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03090"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_073903873.1"
                     /transl_table=11
                     /translation="MGGTAGTEHLGVRREGATLVLTLNRPEAKNALSLPMLVGLYDGWL
                     EADADDGIRSVVLTGAGGSFCAGMDLKALAGKGMEGEQYRDRLKADPDLHWKAMLRHHR
                     PRKPVIAAVEGYCVAGGTEILQGTDIRVAAASATFGLFEVRRGLFPIGGSTVRLPRQIA
                     RTHALEMLLTGRPYSAEEAARIGLVGRVVPDGTALDAALGIAERINACGPLAVEAVKAS
                     VYETAEMTETEGLAAELKRGWPVFDTADAKEGARAFAEKRTPEYRRE"
     aSDomain        984..1730
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK27_RS03145_ECH.1"
                     /evalue="4.90E-54"
                     /label="AMK27_RS03145_ECH.1"
                     /locus_tag="AMK27_RS03145"
                     /protein_end="261"
                     /protein_start="12"
                     /score="175.1"
                     /tool="antismash"
                     /translation="RREGATLVLTLNRPEAKNALSLPMLVGLYDGWLEADADDGIRSVV
                     LTGAGGSFCAGMDLKALAGKGMEGEQYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGY
                     CVAGGTEILQGTDIRVAAASATFGLFEVRRGLFPIGGSTVRLPRQIARTHALEMLLTGR
                     PYSAEEAARIGLVGRVVPDGTALDAALGIAERINACGPLAVEAVKASVYETAEMTETEG
                     LAAELKRGWPVFDTADAKEGARAFAEK"
     gene            1828..2817
                     /locus_tag="AMK27_RS03150"
                     /old_locus_tag="AMK27_03095"
     CDS             1828..2817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058750.1"
                     /locus_tag="AMK27_RS03150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03095"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_073902468.1"
                     /transl_table=11
                     /translation="MTPPSEVLRAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRTES
                     GEVLVPPVEYDPATAAELRDLVEVGTTGTVTTWAWNPAPRPAQPLATPFAWVLVRLDGA
                     DTALLHALDAPGPEAVRTGMRVRVRWAAERSGAITDIACFEPHDSDPVAEPGPDPVAER
                     VADPVAHDGRFDDPVTGIVAPARLDYTYSPGRAQTRYLHALGERRTVGERCPSCAKVYV
                     PPRGACPTCGVATTDRVEVGPRGTVTTYCIVNIKAKNLDIEVPYVYAHIALDGAGLALH
                     GRIGGIPYDQVRMGLRVEPVWSEEGRYPDHYRPTGEPDADYDTYKELL"
     gene            2814..3884
                     /locus_tag="AMK27_RS03155"
                     /old_locus_tag="AMK27_03100"
     CDS             2814..3884
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031484.1"
                     /locus_tag="AMK27_RS03155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03100"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_073902469.1"
                     /transl_table=11
                     /translation="MTPHRPAREVAIVAFAQSDHRRRTDDLSEVEMVMPVLHDVLRQTG
                     LRTSDIGFTCSGSSDYLAGRAFSFTMALDGVGAWPPISESHVETDGAWALYEAWVKLLT
                     GEADTALVYSYGKCSPGSVRDVLTRQLDPYYLAPLWPDSVALAALQAQALVDAGATDEP
                     ALAAIAGRSREDAAANPHAQLPGARPQGEYVVQPLRTGDCPPIGDGAAAVILAVGDRAR
                     ELCSRPAWIRGMDHRIEAHSLGVRDLTDSPSTRLAAERAGAFEAPVDTAELHAPFTSQE
                     VVLRRALDLDRSVRVNPSGGALAANPVMAAGLIRLGEAAARIHRGDSDRALAHATSGPC
                     LQQNLVAVLEGEPHVR"
     gene            3874..5058
                     /locus_tag="AMK27_RS03160"
                     /old_locus_tag="AMK27_03105"
     CDS             3874..5058
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031483.1"
                     /locus_tag="AMK27_RS03160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03105"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_073902470.1"
                     /transl_table=11
                     /translation="MSGKAVTSKEPVAVVGVGQTKHVAARGDVSIAGLVREAAVRALED
                     AELTWADIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAA
                     NLVAARVHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGA
                     PDAIGSLVAYKDRRNALKNPYAHLHEHDLTLEKVQASPMLWDPIRYSETCPSSDGACAM
                     VLTDRTGAARSPRPPAWVHGGAMRSEPTLFAGKDFVSPQAGRDCAADVYRQAGITDPRR
                     EIDAVEMYVPFSWYEPMWLENLGFAEEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPI
                     GASGMIRFAEAALQVRGEAGEHQVDGAHRALGHAYGGGAQFFAMWLVGDTPPTG"
     gene            5095..5514
                     /locus_tag="AMK27_RS03165"
                     /old_locus_tag="AMK27_03110"
     CDS             5095..5514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890858.1"
                     /locus_tag="AMK27_RS03165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03110"
                     /product="ACT domain-containing protein"
                     /protein_id="WP_073902471.1"
                     /transl_table=11
                     /translation="MNAERDLTRLLAGMRPELDPGRYVFTTVEGPAPAGVAPVVTVTED
                     EGLTLVVRQEEADAAGLPYDYVAGRITLRVHSALDAVGLTAAVAGALAGEGLSCNVVAG
                     FHHDHLFVEHARADEALAVLEGLTAGGSGDPRGQA"
     gene            6242..9016
                     /locus_tag="AMK27_RS03170"
                     /old_locus_tag="AMK27_03115"
     CDS             6242..9016
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530292.1"
                     /locus_tag="AMK27_RS03170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03115"
                     /product="AAA family ATPase"
                     /protein_id="WP_241847360.1"
                     /transl_table=11
                     /translation="MLAYAAPAGLGKTTLLTEIRRRAGARGCTVLSARGGDQEQRVPFH
                     VARQLLQPQLAHAADAELRERLGSWYDIVGPALGLRASAEGSPPDPQGLRDGLDWVLTH
                     LAVRRAPLVVVLDDVHWADPESLGWLAAFAPRAEELPMLLVVAYRPDELPAEGVEFTGR
                     RSGQRPLDLAPLTSSAVARLVRDRVGAHADDSFCRDFWSVTAGNPFEAVELAAKVRDQG
                     LEPTADGAHELPDLSAALKGSGLVTRLERLGPATVRLAWACAVLGTEISPQLAGAVAGL
                     GDEAVADCAARLREARVLAEAEQADDPLQFVHPLIATTVYRSIPDATRVALHGQAAWCV
                     VDAGLGPTAAARHLLETHPEGDPWVVAQLRAAAGENLRAGAPDAARRFLARALREPPAP
                     GDRAAVLYELGCSSLLTEPATTVNHLRAALEEPVGDPALRHGIVYRLAQVLAHSDRLVE
                     ASELLGEEARVATDARSRLRMQAEKFMWDALRADEPESPARSRRLAALADRLTGRDVTE
                     RYIIGLRAWDATLRAEPASLALKEAERALEGGLTWADESRGFEVPVLVALLHLYADRPG
                     RAEELFAAGTAEFEKQGWRGAHLAFAYTLIGYIRFRRGRLMEAEDFARAGLRLAERVGA
                     RTPALWYATGVMIEVLIARGRTEEAVQVAREHDFGEPFPAAVTIPDCETVHAELLLATG
                     RTQEAAEELAAVGRRLDPRGKRNPSCCPWQLHLALAEAATSPSKALATAHEAVARARQY
                     GAPSAIGQALRVTAEVSEPADRVKLLEESVDWLDQSPAAYELARSLVALGAALRRTERA
                     AEAAEHLYRGLEAAQDCGADALVEVARAELAAAGLRPRALHPAGTDTLTARERAAADLT
                     VRDQDATAILGVDATTVARLLSAVYRKLGTDRTGLAQALRNTGREPRDPAGQD"
     gene            9073..9573
                     /locus_tag="AMK27_RS03175"
                     /old_locus_tag="AMK27_03120"
     CDS             9073..9573
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="AMK27_RS03175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03120"
                     /product="hypothetical protein"
                     /protein_id="WP_073902472.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLFGGRGPAMIIGNLPEGSPARELTDGQIPFEVAQLLAALENDEPVEVLDTEDV
                     PVMQGDNLLIVRRLKLSESRISCVQFDRSDNVLVTIASWDRPITDDLYALLKPLPAELF
                     QQG"
     gene            9590..9955
                     /locus_tag="AMK27_RS03180"
                     /old_locus_tag="AMK27_03125"
     CDS             9590..9955
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031477.1"
                     /locus_tag="AMK27_RS03180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03125"
                     /product="S4 domain-containing protein"
                     /protein_id="WP_030314775.1"
                     /transl_table=11
                     /translation="MSARVDSWIWAVRLTKTRAQAAAACRAGHVKVNGERAKPAQAVKP
                     GDEVRVFHGGRERIVEVKELHTKRVGPPVAVEAYVDNSPPPPPREHVAVAAVRDRGAGR
                     PTKRDRRELDELRGRHS"
     gene            complement(10001..12199)
                     /locus_tag="AMK27_RS03185"
                     /old_locus_tag="AMK27_03130"
     CDS             complement(10001..12199)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031476.1"
                     /locus_tag="AMK27_RS03185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03130"
                     /product="Geosmin synthase"
                     /protein_id="WP_073902473.1"
                     /sec_met_domain="T1TS (E-value: 2.1e-82, bitscore: 274.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQPFVMPDFYVPYPARLNPHLEAARTHTRDWAREMGMLEGSGVW
                     EQHDLDSHDYALLCSYTHPDCDEEALNLVTDWYTWVFFFDDHFLEIFKRPQDRAGGKTY
                     LDRLPLFMPADPAAGMPEPTNPVEAGLADLWLRTVPAMSAGWRVRFAEATEHLLYESLW
                     ELDNINDGRIANPVEYIEMRRKVGGAPWSAGLVEYAAGAEVPAQVAYSRPLRVLRDAFS
                     DAVHLRNDLFSYQREVEDEGENSNGVLVLEKFLGCTTQEAANAVNDLLTSRLQQFENTA
                     LTEVPLLAAEKGLDAAECAAVAAYAKGLQDWQSGGHEWHMRSSRYMNEGMVGGPSHLEG
                     VLGTSALDIRTLFGRPAASRLRALTHVPHQPVGPSLLPEFDLPYPLALSPHHAEARRLS
                     LDWAERFGLLDDLWDRPLAEGFDLALCSAGLDPDATLEELELSAEWLTWGTYGDDYYPA
                     VFGRSRNLRGAKEQTERFKSCLTLDDPAAGTALAANPLERSLADLWARTAGPMTPGARG
                     QLRYALDAMLDSWLWELHNQAQHRVPDPVDYIEMRRSTFGSELTMLMARLRHDEALPPE
                     LFRSGTVRALENAVMDYGTLINDLFSYQKEIEVEGEVHNGVLVLQKFFDCDYPTAVAMV
                     DDLMRGRLRQYEHLKKREVPLLYQDFGLDAAGRSAFGAYLRELEDWLAGILNWHRKVRR
                     YAAEDVHAGSGAALLRRGPTGLGTSAARMADLLGPVGV"
     gene            complement(12359..14290)
                     /locus_tag="AMK27_RS03190"
                     /old_locus_tag="AMK27_03135"
     CDS             complement(12359..14290)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031475.1"
                     /locus_tag="AMK27_RS03190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03135"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_073903875.1"
                     /transl_table=11
                     /translation="MVALASTALLLPLLSAAPPAGAEAPDAGVLQEQFARAAARHGVPE
                     SVLLAVAYIQSRWDAHGGAPSVTGGYGPMHLTDAVTALAEAPPHHSDGTEDPRGDSSRA
                     VRSGAGATEPAAVPSAGSLPARLRTLERASALSGIPAEELRTRTAANVEGGAALLAAAQ
                     RESGRPASADPADWYGAVARYSGADDSATATRYADDVFDVIRSGESRTTDSGQTVTLAA
                     APAVAPDTAQIAGLGLRPPAGGPVECPRTVACEWIPAPYEEFGDGDYGNHDKANRPASQ
                     SIDYIVVHDTEATWDVTLKLVQDPTYVSWQYSLRSSDGHVAQHVALKDVGWHAGNWFVN
                     AKSVGLEHEGFLTAPDSWYTEAMYRSSARLVRYLAARYDIPLDRQHILGHDNVPGTVTS
                     TIKGMHTDPGPYWDWAHYFTLLGRPITPSAGPRSGVVTIRPDFGSHRPVYTGCASAGEA
                     CAPHGSGAVRLHTAPSADAPLVRDIGLRPDGQESTTGVNDTGARASTGQSYAVAERRGD
                     WTAVWYLGQKAWFHNPAKEPTAVNARGLVLTPREGLASVPVYGRAYPEASAYPTGVPVQ
                     AVSPLPYQLLAGQRYVVGDRTPGEYYFAPVFDSSGHTVVRGQEQYYQIQFGHRVAFVKA
                     ADVRVSPS"
     misc_feature    complement(14524..14539)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            complement(14643..15770)
                     /locus_tag="AMK27_RS03195"
                     /old_locus_tag="AMK27_03140"
     CDS             complement(14643..15770)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="AMK27_RS03195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03140"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_073902474.1"
                     /sec_met_domain="APH (E-value: 6.7e-17, bitscore: 58.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPQHRIVPAGAGPYLAPAPQAVRPRRWVTGTGT
                     QPISGRIDLSGPQGAQLKIAIASVHRICPEFNPVQVLRRSGRSVLIVGTTGRTTAVAKC
                     LLDHSPAWVERFRHEIASYRSFVRHRPPVRAPRLIAADPENCTLVIERMPGRAAALSRH
                     PVEAPPRADVRAALGAIARLNAWRPPAGTFDAPLDYGARIARYHELGLFTDRDRDDLQK
                     LLHGLSHAGGRQGMGQFCHGDALLSNILLSPAGPVLVDWEHAGWYLPGYDLATLWAVLG
                     DAPLARRQISQLAQQAGAASRDAFLVNLMIVLTREIRTYETAVQRTMKEAPPAGSVPVP
                     TGALAPGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    complement(15456..15458)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16005..17498
                     /locus_tag="AMK27_RS03200"
                     /old_locus_tag="AMK27_03145"
     CDS             16005..17498
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031473.1"
                     /locus_tag="AMK27_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03145"
                     /product="hypothetical protein"
                     /protein_id="WP_073902475.1"
                     /transl_table=11
                     /translation="MSGHTNTRLADLFGLAGWSKGELARLVNRQAAAMGHPQLATDTSR
                     VRRWIDRGETPRDPVPRVLAALFTERLGRVVTIEDLGFVRHGRSGKQQDVRKTENPDGL
                     PWAPDRTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSVLSNAMHDWLQTDPARQRAPQR
                     ASDPLHADPAGFDRYEAAPIGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHADHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAQDGSGERVLPRTRAMFHTIEAWAQASMGRGQA
                     MRRTLGEAEDLFVSDRRDEEHPSWMQNFDEADLHGMQALAYRTLADHDPAAAVPAQRHA
                     KLALELRRGGHNRSKLFDHISLASACFIADDPEQADRYARLALMSMGETSSHRTWDRLR
                     EMYRLTGQYAGYARIEHLREEIELALPRSPVNRPRTGQA"
     misc_feature    16047..16062
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.1"
                     /tool="antismash"
     gene            complement(17711..19180)
                     /locus_tag="AMK27_RS03205"
                     /old_locus_tag="AMK27_03150"
     CDS             complement(17711..19180)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571683.1"
                     /locus_tag="AMK27_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03150"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_073902476.1"
                     /transl_table=11
                     /translation="MPSPLFADHPAQQPEPGAVDALISQTRRLRGELVAVRREAVVNDD
                     DPQQRWQRALCDLAVHQLDDLGAHLGQLRAGVPEQLVTEEPAETAPDTSLPTAPGTAYG
                     EVAPQRTGSLLSRVGSAEWNLLTDEVSWSEELFQIFGRTRENGPMSLDEMPTMVFVDDQ
                     PVLQTMVTDCLIDGKPIDGEFRIVRTDGCVRTVHMTGEPVLDADGCTASMWAVLRDVSE
                     LRRSERAVRESRDSLERSRHIEQTERRVAVELQEAVLPPWRGSLRFAHDGPAPLDVAAH
                     YLPAASTGLIGGDWYDALALPDGDALLTVGDLTGHGVAATSSMAMLLGALRGMAVAGIR
                     PAALMGHLNQLLETSVQPALGSAMCCRYDPVAQTLTWAQAGHPAPLLFRDGTGHVLRRP
                     EGVLLGATTGAVYGEAETRLIPGDLLVLHTDGLTRGSGADDDTGTRRLLALGRRLSGAR
                     DSQDGVRAVVEEFGEEQREDDACVMVVRVGH"
     gene            19675..20682
                     /locus_tag="AMK27_RS03210"
                     /old_locus_tag="AMK27_03155"
     CDS             19675..20682
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975157.1"
                     /locus_tag="AMK27_RS03210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03155"
                     /product="hypothetical protein"
                     /protein_id="WP_198955808.1"
                     /transl_table=11
                     /translation="MDAASVLPVLAAVPPGVLTGTGTATLVELADPLDPQTVLTRLRAA
                     AASPGPLVLCLAGQLHLDRRQQLPHLALARTTPATLRYTALPWHWLGAELAARAPGTTT
                     VVADLAADPAVCERLTTTPGFLHLGPGPTLYGRVTPAPRRGELLAPAYLRSWAELWRSG
                     ARLPYATLHAESAARAAGATPEAFLLAPAPVPAPVADQDPHPAILAAATAGRHGEAAAV
                     AAAWEREALRRHGPRSAEAVHWTEVRADLARLAGEPARSCELWLSAAEARLALGQRTDD
                     PDVEGAVDRAHHQWERIVDRARARALGPVLITLRQRVPGRRPGALAALKRRMAD"
     gene            20761..21963
                     /locus_tag="AMK27_RS03215"
                     /old_locus_tag="AMK27_03160"
     CDS             20761..21963
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151325.1"
                     /locus_tag="AMK27_RS03215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK27_03160"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_073902477.1"
                     /sec_met_domain="PALP (E-value: 7e-61, bitscore: 202.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLATTQRSLADPSVHHPLWPPLTEGCPITSTDEVAHPLDIDYA
                     YDEVPADLFARPAAHGLERWSPLLPPLAAPGLGEGNTPLVELPDGVWIKDESRNPTWSH
                     KDRLNRVAISAAVASGALGVVVSSSGNHGAAAAAYAARAGLPCAVFTAPDAPPAVASHL
                     RAYGATVLTLPYESVRPLMRRIVDELGFQNVSSVTDTAHTGHPFGPEGYKTIAYEIALD
                     LGRAPAAVHVPTGYGELLFGVAKGFQELVRLGVTDSVPRLYATEPAAAGALAEALRTGA
                     PVARVPVGPTTAYAIDCEVNSYRGVLAVRATGGAARTVTDAQMAAAQDELAAQGLWCET
                     SAAAGLAGLRAHGPREDEGPVVCVVTSSGYKDVATGRDTAAPTAADWATIEASLKEARG
                     R"
ORIGIN
        1 cacgtacttg cggtgcagga cgacccgctg gccgtagttg aaggcgatga acgcggtcag
       61 cgtggaggtg ccgtgcatca ggggcggcgc ggggaagaag gtgatgccgg cgccgccggc
      121 ggcgacccgc tcggccagtt cctcggggcg cttcaccgct tcgcccgagg ggtccccgcc
      181 gaagagaccg gcgaagaaca ggtcctcctg gcgccacagg acgcccttgg gcatcccggt
      241 cgtgccgccg gtgtagatga tgaagaggtc gtcggccgag cgcggtccga agccgcgcgc
      301 gggtgaaccg gcggcctccg cctcggtgta ggggacgcag tccacctccg cggcgctctc
      361 gggcggggtc cccacccgca cgaggtgccg cagcttctcc gtctgcggca gcgccgccgc
      421 gacccggtcg gtgaactcgg cgtcgaagac gagtgcggcc aggtcggcgt cccggtagag
      481 gtagacgagc tcctcctcca cgtaccggta gttcacgttg accggaacga tccgcgcctt
      541 gaggcaggcg aggacggtct gcaggtactc gatgccgttg tacaggtgga ggccgaggtg
      601 ttcgccgggc cggatgcccg cgtcgacgag gtggtgcgcg atccggttgg cggcctcgtc
      661 gagtccggcg taggtgagcc ggcgctcctc gcccgtcccc ggatggtcga cgtacaccag
      721 cgcctcgcgg tcggggaccg cgtcgacgac cgattcgaac aggtcggcaa ggttgtactc
      781 caccgttcct cctgaccccg gttcgcactg actcggcggt cattagagcg ccgaccggcg
      841 acagggggaa gggggtgcgc agaagaatct gactgagtgt cagaaaacta ttgaactgga
      901 cccccggcta ctgcaacctg ttccagaact ggagacggga gacccccatg ggcggcactg
      961 ctggcaccga acacctcggc gtacggcgcg aaggcgccac gctcgtcctc accttgaacc
     1021 ggcccgaggc caagaacgcc ctctcgctgc cgatgctcgt cggcctctac gacggctggc
     1081 tggaggccga cgccgacgac ggcatccgct ccgtcgtcct caccggcgcg ggcggctcct
     1141 tctgcgcggg catggacctc aaggccctgg ccggcaaagg aatggagggc gagcagtacc
     1201 gggaccggct caaggccgac cccgacctgc actggaaggc gatgctgcgc caccaccgcc
     1261 cccgcaaacc cgtcatcgcc gcggtggagg gctactgcgt cgccggcggc accgagatcc
     1321 tccagggcac cgacatccgg gtcgcggccg cctcggcgac cttcggactc ttcgaggtcc
     1381 ggcgcggact gttcccgatc ggcggctcca cggtccgcct gccccggcag atcgcccgga
     1441 cccacgccct cgagatgctc ctcacgggcc gcccctactc ggcggaggag gccgccagga
     1501 tcggcctcgt cggccgggtc gtccccgacg gcaccgccct cgacgcggcc ctcggcatcg
     1561 ccgagcggat caacgcctgc ggaccgctcg ccgtcgaggc agtgaaggcc tccgtctacg
     1621 agaccgccga gatgacggag acggagggcc tggccgccga actcaagcgc ggctggccgg
     1681 tcttcgacac ggcggacgcg aaggaggggg cgagggcgtt cgccgagaag cggacgccgg
     1741 agtaccgacg ggagtgacgg gcgagcgggg tcagaccccc gcgcagcggc ccccgcaccc
     1801 accaccgacc gcccacaagg agcccgcatg acacctccgt cggaagtcct ccgcgcaccc
     1861 ctcgtcgtcg aattcccctt cacccgttcc ctcggccccg tccagtccgc cttcctcacc
     1921 ggcctccgcg agcggaccgt cctcggcgtc cgcaccgagt ccggcgaggt cctcgtcccg
     1981 cccgtcgagt acgaccccgc caccgccgcc gagctccgcg acctcgtcga ggtgggcacc
     2041 accggaaccg tcaccacctg ggcctggaac cccgcgcccc gccccgcgca gcccctcgcg
     2101 acccccttcg cctgggtcct cgtccgtctc gacggcgccg acaccgccct cctgcacgcc
     2161 ctcgacgccc ccggtcccga ggccgtccgg accggcatgc gcgtccgtgt ccgctgggcc
     2221 gccgaacggt ccggtgccat cacggacatc gcgtgcttcg agccgcacga cagcgacccg
     2281 gtcgccgaac ccggccccga cccggtcgcc gaacgggtcg ccgatccggt cgcccacgac
     2341 ggccggttcg acgaccccgt caccggcatc gtcgcccccg cccgcctcga ctacacctac
     2401 agccccggcc gcgcccagac ccgctacctg cacgccctcg gcgagcggcg gaccgtcggc
     2461 gagcgctgcc cctcctgcgc caaggtctac gtgccgcccc gcggcgcctg ccccacctgc
     2521 ggagtcgcca ccaccgaccg ggtcgaggtc ggaccgcgcg ggaccgtcac cacgtactgc
     2581 atcgtcaaca tcaaggcgaa gaacctcgac atcgaggtcc cgtacgtcta cgcccacatc
     2641 gccctcgacg gcgccggcct cgccctccac ggccgcatcg gcggcatccc gtacgaccag
     2701 gtccgcatgg gtctgcgcgt cgagcccgtg tggagcgagg aaggccgcta ccccgaccac
     2761 taccggccca ccggcgagcc cgacgccgac tacgacacct acaaggagct gctgtgacgc
     2821 cgcaccggcc ggcccgcgag gtggcgatcg tcgccttcgc ccagagcgac caccgccgcc
     2881 gcaccgacga cctctccgag gtcgagatgg tcatgcccgt cctgcacgac gtcctgcggc
     2941 agaccggcct caggacctcc gacatcggct tcacctgctc cggttcctcc gactacctgg
     3001 cgggccgcgc cttctccttc acgatggcac tcgacggcgt cggcgcctgg ccgccgatct
     3061 ccgagtccca cgtcgagacg gacggcgcct gggcgctcta cgaggcctgg gtgaagctcc
     3121 tcaccggcga ggccgacacc gccctcgtct actcctacgg caagtgctcg cccggctccg
     3181 tccgcgacgt cctcacccgc cagctcgacc cctactacct ggccccgctc tggccggact
     3241 cggtcgccct cgccgccctt caggcgcagg cgctcgtcga cgcgggcgcc accgacgaac
     3301 ccgccctcgc ggcgatcgcc ggccgcagcc gcgaggacgc cgccgcgaac ccccacgccc
     3361 agctgcccgg cgcccgcccc cagggcgagt acgtcgtcca gccgctgcgc accggcgact
     3421 gcccgcccat cggcgacggc gccgccgccg tgatcctcgc cgtcggcgac cgggcccgcg
     3481 aactctgctc ccgccccgcc tggatccggg gcatggacca ccgcatcgag gcccactccc
     3541 tcggtgtccg cgacctcacc gactcgccct ccacccgcct cgccgccgaa cgcgccggag
     3601 ccttcgaggc ccccgtcgac accgccgaac tccacgcgcc cttcacctcc caggaggtcg
     3661 tcctgcgccg ggccctcgac ctcgaccgga gcgtgcgggt caacccgtcc ggcggagcgc
     3721 tcgccgccaa ccccgtcatg gccgccggcc tcatccggct cggcgaggcc gccgcccgca
     3781 tccaccgggg cgactccgac cgcgccctcg cccacgccac ctccgggccc tgcctccagc
     3841 agaacctggt cgccgtcctg gaaggagagc cgcatgtccg gtaaggccgt gacatcgaag
     3901 gagcccgtcg ccgtcgtcgg cgtgggccag accaagcacg tcgccgcccg cggggacgtg
     3961 tcgatcgccg gactcgtccg cgaggccgcc gtccgggccc tggaggacgc ggagctgacc
     4021 tgggcggaca tcgacgccgt cgtcatcggc aaggcgcccg acttcttcga gggcgtgatg
     4081 atgccggagc tgtacctcgc cgacgcgctc ggcgcggtcg gcaagcccat gctccgggtg
     4141 cacacggccg gatccgtcgg cggctccacc gcgctggtcg ccgccaacct ggtcgccgcc
     4201 cgcgtccacc gcaccgtcct caccctggcg ttcgagaagc agtccgagtc caacgccatg
     4261 tggggcctct ccctgcccgt gcccttccag cagccgctgc tcgccggagc cggcggcttc
     4321 ttcgcgccgc acgtgcgcgc gtacatgcgg cggaccggcg cgcccgacgc gatcggctcc
     4381 ctcgtcgcgt acaaggaccg gcgcaacgcg ctcaagaacc cgtacgccca tctccacgag
     4441 cacgacctca ccctggagaa ggtgcaggcc tccccgatgc tctgggaccc gatccgctac
     4501 tccgagacct gcccctcgtc ggacggcgcg tgtgcgatgg tcctcaccga ccggacgggc
     4561 gccgcccgtt cgccccgccc gcccgcctgg gtgcacggcg gcgcgatgcg cagcgaaccg
     4621 accctcttcg ccggcaagga cttcgtctct ccgcaggcgg gccgggactg cgccgccgac
     4681 gtctaccggc aggccggcat caccgacccc cgacgtgaga tcgacgccgt cgagatgtac
     4741 gtgccgttct cctggtacga gccgatgtgg ctggagaacc tcggcttcgc ggaggagggc
     4801 gagggctgga agctcaccga ggcgggggtg accgaactcg acggcgacct gcccgtgaac
     4861 ccgtccggcg gagtgctctc caccaacccc atcggggcgt ccgggatgat ccgcttcgcc
     4921 gaggccgcgc tccaggtgcg cggcgaggcg ggcgagcacc aggtcgacgg cgcccaccgg
     4981 gccctgggcc acgcctacgg aggcggcgcc cagttcttcg ccatgtggct cgtgggagac
     5041 accccgccca ccgggtgagc cgcgccgccg ggccgggcgc ctaccctggc ggccatgaac
     5101 gcggaacgtg atctcacccg gctgctcgcc gggatgcggc cggagctcga ccccggccgc
     5161 tacgtcttca ccacggtgga aggccccgcc ccggccgggg tcgcaccggt ggtcaccgtc
     5221 accgaggacg agggcctcac cctcgtcgta cggcaggagg aggcggacgc cgccggcctc
     5281 ccgtacgact acgtggcggg ccggatcacc ctgcgcgtgc actccgcgct cgacgccgtc
     5341 ggactgacgg ccgccgtcgc cggcgcgctc gccggggagg gactcagctg caacgtggtg
     5401 gcgggcttcc accacgacca cctcttcgtg gaacacgcgc gcgcggacga ggcgttggcc
     5461 gtgctcgaag ggctcacggc aggcggatcc ggcgaccccc gcgggcaggc ctgaggacgg
     5521 tcgccggggc acccgggcga ggccgtcgga caccggacgt ccgacggcac ctccgccggc
     5581 cgggagccgc aggtcacccg gtccgccgac accggcccga ccagggcgga cgcggccgcg
     5641 acggccgcgg cgaaggcgct ttccaccgct ccgcgccgaa ccgaatatgc cagctgcgac
     5701 acggcgggat tttgcttggc cgtttgaccg ccccacctca ctccttcggg cgtacgctgg
     5761 gactttcgcg gggcttcccg ctcggcactc ctcaccgtgc gccgggcgcg cgccccctgt
     5821 gtgggggtgg aacgtggcac gtcaggaagg cgcgtcggtc cgtcagggag ccggcctctt
     5881 cgagcgcgag gccgcgctcg ccgcagccga ggaggcgctc gacctcctga ccggtctgtc
     5941 ggacgagccg ttgtggccgg tcgccgtacc ctcaccccgc gagacgcgcg gcccgcacct
     6001 cgtcgccgtc cccgacgaat cctccgccca ggacaccgat caggcgaccg gcccgctgcc
     6061 cacaccgtcc gcggaccacc ggggccccgg cggccgtacc gggctgcgac ccgtgcccga
     6121 cagcggcgcc ggacccgcgt cgcttccgga gcaccggccc ggccccggtt ccgtgttcac
     6181 ctccgcggcc gacgacggcg ccgcgaccgc cgcgcgcccc caagtcctcc gccgcggcgg
     6241 catactcgcc tacgccgccc ccgccggcct cggcaagacc accctgctca ccgagatccg
     6301 gcgccgcgcc ggcgcccgcg gctgcaccgt gctctccgcg cgcggcggcg accaggagca
     6361 gcgggtcccg ttccacgtcg cccggcagct cctccagccg cagctggccc acgccgccga
     6421 cgccgaactc cgcgagcgtc tcggctcctg gtacgacatc gtcggccccg cactcgggct
     6481 ccgcgcctcc gccgaaggct ccccgcccga cccgcagggt ctgcgcgacg gactcgactg
     6541 ggtcctcacc cacctcgccg tccgccgcgc gcccctcgtc gtggtcctgg acgacgtcca
     6601 ctgggccgac cccgagtccc tcggctggct cgccgcgttc gccccgcgcg ccgaggagct
     6661 gcccatgctc ctcgtcgtcg cctaccgccc cgacgaactc cccgccgagg gagtcgagtt
     6721 caccggacga cggtccggcc agcgccctct ggacctcgcc ccgctgacct cgtccgccgt
     6781 cgcccggctc gtccgcgacc gcgtcggcgc ccacgccgac gacagcttct gccgcgactt
     6841 ctggtccgtc accgccggca accccttcga ggcggtcgaa ctcgccgcca aggtccgtga
     6901 ccagggcctc gaacccaccg ccgacggagc ccacgaactc cccgacctct ccgccgccct
     6961 caagggcagc ggcctcgtca cccggctcga acggctcgga cccgccaccg tccgcctcgc
     7021 ctgggcctgc gcggtcctcg gcaccgagat ctcaccccag ctggcaggcg ccgtcgccgg
     7081 tctcggggac gaggccgtcg ccgactgcgc cgcccggctc cgcgaggcgc gcgtcctcgc
     7141 cgaggccgaa caggccgacg atcccctcca gttcgtccac ccgctcatcg cgaccaccgt
     7201 ctaccgctcc atcccggacg ccacccgcgt cgccctgcac ggtcaggccg cctggtgcgt
     7261 cgtcgacgcc gggctcggcc ccaccgcggc cgcccgccac ctcctggaga cccatcccga
     7321 gggcgacccc tgggtcgtcg cccagctgcg cgccgccgcc ggcgagaacc tccgcgccgg
     7381 agcccccgac gcggcccgcc gcttcctcgc ccgcgccctg cgggagccgc ccgcccccgg
     7441 cgaccgggcc gccgtcctct acgaactcgg ctgctcctcg ctcctcaccg agcccgccac
     7501 caccgtcaac catctgcggg ccgccctgga ggaaccggtc ggcgacccgg cgctccgcca
     7561 cggcatcgtc taccgcctcg cccaggtcct cgcccacagc gaccgcctcg tcgaggcctc
     7621 cgagctgctc ggcgaggagg cccgggtcgc gaccgacgcc cgcagccgac tgcggatgca
     7681 ggccgagaag ttcatgtggg acgccctgcg cgccgacgaa ccggagtcgc ccgcccggtc
     7741 ccggcgcctc gcggcgctcg ccgaccggct caccggccgc gacgtcaccg agcggtacat
     7801 catcgggctc cgcgcctggg acgccaccct gcgcgccgaa cccgcctcgc tcgccctgaa
     7861 ggaggccgag cgcgccctcg aaggcggcct cacctgggcc gacgagagcc ggggcttcga
     7921 ggtcccggtc ctcgtggccc tgctccacct ctacgccgac cggcccggcc gcgccgagga
     7981 gctcttcgcc gccggaaccg ccgaattcga gaagcagggc tggcgcgggg cgcacctcgc
     8041 cttcgcgtac accctcatcg gctacatccg cttccggcgc ggccggctga tggaggccga
     8101 ggacttcgcc cgcgccggac tccgcctcgc cgagcgcgtc ggcgcccgca cccccgccct
     8161 ctggtacgcc accggcgtca tgatcgaggt cctcatcgcc cgcggccgta cggaagaggc
     8221 cgtgcaggtc gcccgcgagc acgacttcgg cgagccgttc cccgcagccg tcaccatccc
     8281 cgactgcgag accgtccacg ccgaactgct gctcgccacc ggccgcaccc aggaggccgc
     8341 cgaggagctg gccgccgtcg gcaggcgcct cgacccgcgg ggcaagcgca acccctcctg
     8401 ctgcccctgg cagctccacc tcgcgctcgc cgaggcggcg acctccccgt cgaaggccct
     8461 cgccaccgcc cacgaggccg tcgcccgcgc ccgccagtac ggggcgccct ccgcgatcgg
     8521 ccaggcgctc cgcgtgaccg ccgaggtgtc cgagcccgcc gaccgcgtga agctcctgga
     8581 ggagtccgtc gactggctgg accagtcgcc cgccgcgtac gagctggccc gctccctcgt
     8641 cgcgctcggc gcggccctgc gccgcaccga gcgtgccgcg gaggccgccg agcacctcta
     8701 ccggggcctg gaggccgccc aggactgcgg cgccgacgcc ctcgtcgagg tggcccgcgc
     8761 cgagctcgcg gcggccgggc tccgcccccg ggccctccac cccgcgggca cggacacgct
     8821 caccgcccgt gagcgcgccg ccgccgatct caccgtccgc gaccaggacg cgaccgcgat
     8881 cctcggtgtc gacgccacca ccgtggcccg gctcctctcc gccgtctacc gcaagctcgg
     8941 aaccgaccga acgggcctcg cgcaggccct caggaacacc ggccgggagc cccgggaccc
     9001 cgcaggacag gactgaccgc gccgagccgc ccggcgcgtc gcatcgcgcg ccggggcacg
     9061 taccatggcc gtatgtcctt cctccgccgc cgcagcgccg ccactcccgc gggcccggac
     9121 ttcgatgtcc tggccatgga cccgggggac tggcccggta atctcggcgc cggcctgctg
     9181 cccgctcccg acggctcctg ccagggcgtc ttcctccggt acgacctgtt cggcggccgc
     9241 ggccccgcga tgatcatcgg caatctgccc gagggctccc cggcgcgcga gctcaccgac
     9301 ggccagatcc ccttcgaggt ggcccagctg ctcgccgccc tcgagaacga cgagccggtc
     9361 gaggtcctcg acaccgagga cgtccccgtg atgcagggcg acaacctcct gatcgtccgt
     9421 cgcctcaagc tctccgagag ccgcatctcc tgcgtccagt tcgaccgcag cgacaacgtc
     9481 ctcgtcacga tcgccagttg ggaccggccg atcaccgacg acctgtacgc gctgctcaag
     9541 ccgctgcccg ccgagctgtt ccagcagggc tgacggggag cgggggccga tgagcgcacg
     9601 cgtcgacagc tggatctggg cggtccgcct caccaagacc cgtgcccagg ccgccgcggc
     9661 ctgccgggcc ggacacgtca aggtcaacgg cgagcgggcc aagcccgccc aggcggtgaa
     9721 gcccggcgac gaggtccggg tcttccacgg cgggcgggag cggatcgtcg aggtcaagga
     9781 actccacacc aagcgggtcg gcccgccggt cgccgtcgag gcgtacgtgg acaacagccc
     9841 gcccccgccg ccgcgcgagc acgtggccgt cgccgccgtc cgggaccggg gcgccgggcg
     9901 tcccaccaag cgcgaccgcc gcgaactcga cgagctgcgc ggccggcaca gctgatcgcc
     9961 ggagcgtgga gcggcccgcc gggccgcccc acctcccgcc tcagaccccg accgggccaa
    10021 ggagatccgc catccgggcc gccgaggtgc cgagaccggt cggcccacgc cgcagcagcg
    10081 ccgcaccact gcccgcgtgc acgtcctccg ccgcgtagcg ccgcaccttc cggtgccagt
    10141 tcaggatgcc cgcgagccag tcctccaact cccgcagata tgccccgaag gccgacctgc
    10201 ccgccgcgtc gagcccgaag tcctggtaga gcagggggac ttcacgcttc ttgaggtgct
    10261 cgtactggcg cagccggccg cgcatcaggt cgtcgaccat ggccaccgcc gtggggtagt
    10321 cgcagtcgaa gaacttctgg agcaccagaa cgccgttgtg cacctcgccc tcgacctcga
    10381 tctccttctg gtacgagaac aggtcgttga tcagcgtccc gtagtccatg accgcgttct
    10441 ccagggcgcg cacggtcccc gagcggaaca gttccggcgg cagcgcctcg tcgtgccgca
    10501 accgggccat cagcatggtc agttcggagc cgaaggtgct ccggcgcatc tcgatgtagt
    10561 cgacggggtc gggaacccgg tgctgcgcct ggttgtgcag ctcccacagc cagctgtcca
    10621 gcatggcgtc gagcgcgtac cgcagctggc cgcgggcccc cggcgtcatg gggcccgcgg
    10681 tccgggccca gagatcggcg agcgagcgct ccaacgggtt cgcggcgagc gccgtgcccg
    10741 cggccggatc gtccagtgtc aggcaggact tgaacctctc ggtctgctcc ttggcacccc
    10801 gaaggttccg ggagcggccg aagacggcgg ggtagtagtc gtctccgtag gtcccccagg
    10861 tcagccactc ggcgctgagc tccagctcct ccagagtggc gtccgggtcg agtccggccg
    10921 agcacagggc caggtcgaag ccctccgcca gcggccggtc ccagaggtcg tcgaggagcc
    10981 cgaaccgctc ggcccagtcg agcgacagcc gacgggcctc cgcgtggtgc gggctgaggg
    11041 cgagcgggta cggcaggtcg aactcgggca gcagggaagg gcccacaggc tggtgcggca
    11101 catgggtgag cgcccgcagc cgcgacgctg ccgggcgccc gaagagggtg cggatgtcga
    11161 gggcggaggt gccgagcacc ccttcgaggt gcgaagggcc gccgaccatg ccctcgttca
    11221 tgtaccggct ggagcgcatg tgccactcgt ggccgcccga ctgccagtcc tgcagcccct
    11281 tcgcgtacgc cgcgacggcc gcgcactcgg ccgcgtcgag gcccttctcg gcggcgagca
    11341 gcggcacttc ggtgagggcc gtgttctcga actgctggag ccgtgaggtc agcaggtcgt
    11401 tgacggcgtt cgccgcctcc tgggtcgtgc agccgaggaa cttctcgagg acgagcacgc
    11461 cgttgctgtt ctcgccctcg tcctccacct cgcgctggta cgagaagagg tcgttgcgca
    11521 gatggaccgc gtcggagaag gcgtccctga gcacccgcag cggccgggag tacgccacct
    11581 gggccgggac ctccgcaccc gccgcgtact cgacgagccc cgccgaccag ggcgcgccgc
    11641 ccaccttgcg ccgcatctcg atgtactcga cggggttggc gatccgcccg tcgttgatgt
    11701 tgtcgagctc ccagagggac tcgtacagca ggtgctccgt cgcctccgcg aaccgcaccc
    11761 gccagcctgc cgacatggcg ggaacggtcc gcagccagag gtcggcgagc cccgcctcga
    11821 cggggttggt cggctcgggc atgcccgccg ccgggtccgc cggcatgaac agcggcagcc
    11881 ggtccagata ggtcttgccg ccggcccggt cctggggccg tttgaagatc tccaggaagt
    11941 ggtcgtcgaa gaagaagacc caggtgtacc agtcggtgac gaggttgagc gcctcctcgt
    12001 cgcagtcggg gtgggtgtac gagcagagca gcgcgtagtc gtgcgagtcg aggtcgtgct
    12061 gctcccagac ccccgagccc tccagcatcc ccatctcccg cgcccagtca cgggtgtgcg
    12121 tgcgggcggc ctccaggtgg gggttgagcc gcgccggata cggaacatag aaatccggca
    12181 taacgaaggg ctgaggcatc tgctgaaggg ccttccggtg agcatgagct gtgtccggcc
    12241 cacctttacc cgtcgcccgt acggcgcacg cgatctcccg aatagtccta tgaacgccga
    12301 aagggtggtg ccggatcgtt catccgccac cacccttctg ctttgggcca tgcttgcgtc
    12361 aggacgggga aacccgcacg tcagcagcct tcacaaaggc cactcgatgg ccgaactgga
    12421 tctggtagta ctgctcctgt ccccggacga ccgtgtggcc gctgctgtcg aacaccggcg
    12481 cgaagtagta ctcgcccggg gtccggtcgc ccaccacgta ccgctgcccc gcgagcagct
    12541 ggtacggcag cggcgacacc gcctgcaccg gcacacccgt cggatacgcc gaggcctccg
    12601 gataggcccg cccgtacacc ggcaccgagg ccagcccctc gcggggcgtc aggacgagcc
    12661 cccgcgcgtt caccgccgtc ggctccttcg ccggattgtg gaaccaggcc ttctgcccga
    12721 ggtaccagac cgccgtccag tcgccccggc gctccgccac cgcgtagctc tgcccggtcg
    12781 acgcccgcgc cccggtgtcg ttgaccccgg tggtcgactc ctgcccgtcc ggccgcagac
    12841 cgatgtccct caccaggggc gcgtcggcgc tcggcgcggt gtgcaggcgc accgccccgc
    12901 tgccgtgcgg cgcgcacgcc tcgcctgccg aggcacagcc cgtgtagacc ggcctgtggg
    12961 acccgaagtc gggccggatc gtcaccacac cggaccgggg gccggcactc ggggtgatcg
    13021 gccggccgag cagcgtgaag tagtgcgccc agtcccagta cgggcccggg tccgtgtgca
    13081 tgcccttgat cgtggacgtc accgtccccg gcacgttgtc gtgccccagg atgtgctgcc
    13141 ggtcgagcgg gatgtcgtac cgggcggcga ggtaccgcac gagccgcgcc gacgaccggt
    13201 acatcgcctc cgtgtaccag gagtccggcg cggtgaggaa cccctcgtgc tccaggccca
    13261 cggacttggc gttcacgaac cagttgcccg cgtgccagcc gacgtccttg agcgccacgt
    13321 gctgggcgac gtgcccgtcg gaggagcgca gcgagtactg ccacgagacg tacgtcgggt
    13381 cctgcaccag cttcagggtg acgtcccagg tggcctcggt gtcatggacg acgatgtagt
    13441 cgatcgactg ggaggcgggc cggttcgcct tgtcgtggtt gccgtagtcg ccgtcgccga
    13501 actcctcgta cggcgccggg atccactcgc aggccaccgt gcgcggacac tccacgggcc
    13561 cgccggccgg cgggcgcagg ccgagtccgg cgatctgcgc cgtgtcgggc gcgaccgcgg
    13621 gggcggccgc cagcgtcacc gtctgcccgc tgtccgtcgt ccgcgactcg cccgaccgga
    13681 tcacgtcgaa cacgtcgtcc gcgtaccggg tggcggtcgc cgagtcgtcg gcgcccgagt
    13741 accgcgccac cgccccgtac cagtcggccg ggtccgcgct cgccggccgg ccggactccc
    13801 gctgcgccgc ggccagcagc gccgcgccgc cctcgacgtt cgcggccgta cgggtccgca
    13861 gctcctcggc cggaatcccg gacagcgcgg acgcccgctc cagggtgcgc agccgcgcgg
    13921 gcagcgaacc ggcggacggg acggcggcgg gctcggtcgc ccccgcgccg gagcgcacgg
    13981 cgcgcgagga gtccccgcgc gggtcctccg taccgtccga gtggtgcggc ggcgcctcgg
    14041 caagcgccgt caccgcgtcc gtcagatgca tcggaccgta gccgccggtc acactcggcg
    14101 caccgccgtg ggcgtcccag cgcgactgga tgtacgcgac ggcgaggagc acgctctccg
    14161 gtacgccgtg gcgcgcggcc gcccgcgcga actgttcctg gaggacaccc gcgtcgggcg
    14221 cctcggcacc ggccggcggg gcggcggaca ggagcgggag cagcagggcg gtcgacgcga
    14281 gggcgaccag ggccttcggc agacgacgcg acggcgtacg tccgggggac gcggaacggg
    14341 gcaaggcagc ctccagaggc ggggggtgac accggggcgt gcggggccga acccgtacag
    14401 gggtatcggc tcccggacga tccgtcaatc acgcccacgc acaggcaagt tcccacgtca
    14461 gagcgggaac ggaggcaggc cggcggagtt tcgcggagac gggtcccggg cctgggacgc
    14521 gtcagtggag tggaccattg gctcgccccg ccgagggcgg agacgccagt gcgccgcgtc
    14581 ccggtgtgtc ggcaccgggc acacggcgca ccccccccgt gtcgtcggtc gggcccgccc
    14641 gttcagcgcg tcccgaccgc cgcgcgcacg gcccgccgtg ccatggcgca gtcgtcgtgc
    14701 agccgcctca ggagcagccg ctgttcctcg ccgggcgcga gcgcgcccgt gggcaccggt
    14761 acggaaccgg ccggcggagc ctccttcatg gtgcgctgca ccgccgtctc gtaggtccgg
    14821 atctcccggg tcagcacgat catcaggttc accaggaagg cgtcccggga ggccgcgccc
    14881 gcctgctggg cgagctgact gatctggcgc cgggcgagcg gcgcgtcccc gagtacggcc
    14941 cacagggtcg ccaggtcgta gccgggcagg taccagccgg cgtgctccca gtcgacgagg
    15001 accgggcccg cgggggagag gaggatgttg gagagcaggg cgtcaccgtg gcagaactgg
    15061 cccatgccct ggcggccgcc cgcgtgcgac agcccgtgga gcagcttctg caggtcgtcc
    15121 cggtcccggt cggtgaagag accgagctcg tggtagcggg cgatccgggc gccgtagtcc
    15181 agcggcgcgt cgaacgtccc ggccggcggc cgccaggcgt tgagccgggc gatcgcgccg
    15241 agcgcggccc gcacgtccgc gcggggcggg gcctcgacgg ggtggcgcga gagcgccgcc
    15301 gcccgtcccg gcatccgctc gatcaccagc gtgcagttct ccgggtcggc cgcgatcagc
    15361 cggggcgccc gcaccggcgg acggtggcgg acgaaggagc ggtaggaagc tatctcgtgc
    15421 cggaaccgct cgacccacgc gggggagtgg tccagtaaac acttcgcgac cgccgtggtc
    15481 cgcccggtcg ttccgacgat cagtacggaa cgtccgctgc gccgcagcac ctggaccggg
    15541 ttgaactccg ggcagatgcg gtggacggag gcgatcgcga tcttcagctg cgccccctgg
    15601 gggccggaga gatcgattct cccgctgatc ggctgggtac ccgtgccggt cacccagcgc
    15661 cgcggccgta cggcctgcgg ggcgggtgcg aggtagggtc cggcgccggc cgggacgatc
    15721 cggtgctgcg gccggggcgg ggcggacacg gaggacgatg ctgtgtacat ggaggtgaca
    15781 gatcccttcg tgtgccgacg agttgcgtgc gtcgccccgc ccgccccccg gtccgcaccc
    15841 tggggaatga gggccggtcg gcggggcggg gtggcgcatt cctacctgac acccgggcgc
    15901 gggtggcgga acatctcgcg caccctggcg aagcctggcg aattgtcgcc aggcctatga
    15961 cagagggcta ctgtcaactc agccgagaac ctgggggctt agacgtgagc ggacacacca
    16021 acacccgcct ggcggacctg ttcggcctgg ccggatggtc caagggcgaa ctcgcgagac
    16081 tggtcaaccg gcaggcggcg gccatgggcc acccccagct ggcgaccgac acctcgcggg
    16141 tgcggaggtg gatcgaccgg ggcgagaccc cgcgtgatcc cgtcccccgg gtgctggcag
    16201 cactgttcac cgagcgactc ggccgtgtcg tgaccatcga ggacctcggg ttcgtacgac
    16261 acgggcgcag cggaaagcag caggacgtca ggaagacgga gaaccctgac gggctgccct
    16321 gggcacccga tcgtacggcg gcggtcctca ccgaattcac gggaatggac ctcatgctca
    16381 accgacgcgg cctggtgggc gcgggtgccg cgcttgccgc cggctccgta ctcagcaatg
    16441 ccatgcacga ctggctgcag accgaccccg ctcgccagcg ggccccccag cgggccagcg
    16501 atcccctcca cgccgacccc gccgggttcg accgctacga ggccgccccc atcgggtcgg
    16561 aggagatcga ggcgctggag cactcggtgg aggtgttccg tgcctgggac gcctcccggg
    16621 gtggcggact ccagcgcaag gccgtggtgg gccagctcaa cgaggtgggc ggcatgctcg
    16681 cctaccgcca cgccgaccac cttcagcggc gcctctgggg cgtcgccgcc aacctggccg
    16741 tcctggccgg ctggatgtcc cacgacgtgg gcctcgaacc cacggcgcag aagtacttcg
    16801 tgatcgccgc ccacgcggcc cgcgagggcg gcgaccggcc gagggccggt gaggcgctgt
    16861 cccgtgccgc ccgtcagatg gtgcacctgg gcaggcccga cgacgccctc gacctgatga
    16921 agctcgccca ggacggctcg ggcgaacgcg tcctgcccag gacccgggcc atgttccaca
    16981 ccatcgaggc ctgggcgcag gcctcgatgg gccggggcca ggccatgcgc cgcaccctcg
    17041 gcgaggccga ggacctgttc gtgtccgacc ggcgcgacga ggagcacccc agctggatgc
    17101 agaacttcga cgaggccgac ctgcacggca tgcaggccct cgcgtaccgc accctggcgg
    17161 atcacgaccc ggccgcggcc gtccccgccc agcgccacgc caagctggcg ctcgaactgc
    17221 ggcgcggcgg gcacaaccgc tcgaagctct tcgaccacat ctcgctcgcc tcggcctgct
    17281 tcatcgccga cgaccccgag caggccgacc ggtacgcccg gctcgccctg atgtccatgg
    17341 gggagacctc gtcccaccgc acctgggacc ggctccgcga gatgtaccgg ctcaccgggc
    17401 agtacgccgg ctacgcgagg atcgagcacc ttcgcgagga gatcgagctg gcactgccga
    17461 ggtccccggt caaccggccg aggacggggc aggcctgagg cggccgagcg ccggggggcc
    17521 gggtctgctg tcgatgcggg gatcgccgag gtcggccgtg tcgctgacag ggtgagttcc
    17581 ctctgatcgc gctgccgtgc cacagcgtcg tggtgcgccg gtgcgtgggt ccgtgtagcc
    17641 cggaaccacg atcacggtca cgggttggcg gtcccgcgaa aggtcccgtg tcccgtcgtc
    17701 gcccggtggt tcagtgtccg acccggacaa ccatcacaca ggcgtcgtcc tcgcgctgtt
    17761 cctcgccgaa ctcctcgacg accgcacgca ccccgtcctg ggagtcccgt gccccgctga
    17821 ggcgccggcc gagcgcgagc agtcgtcgcg tacccgtgtc gtcgtcggcg ccgctgccgc
    17881 gggtgagccc gtcggtgtgc aggacgagca ggtcaccggg gatcagccgg gtctcggcct
    17941 cgccgtacac ggctccggtc gtggccccga ggaggacgcc ctcgggccgc cggaggacgt
    18001 gccccgtccc gtcgcggaac agcagcgggg cggggtggcc ggcctgcgcc caggtcaggg
    18061 tctgggcgac cgggtcgtag cggcagcaca tcgcgctgcc gagggccggc tgtacggagg
    18121 tctccaggag ctggttgagg tgacccatca gagcggcggg ccggatcccg gccacggcca
    18181 tgccgcgcag cgcgccgagg agcatggcca tcgaggaggt cgcggcgacc ccgtggcccg
    18241 tcaggtcccc gacggtgagc agcgcgtccc cgtcgggcag ggcgagtgcg tcgtaccagt
    18301 cgccaccgat cagaccggtg ctggcggccg ggaggtagtg cgcggccacg tcgagagggg
    18361 cgggcccgtc gtgggcgaag cggagcgatc cgcgccacgg cgggagcacc gcttcctgga
    18421 gctcgacggc gacccgtcgc tcggtctgct cgatgtggcg gctgcgctcc aggctgtccc
    18481 ggctctcccg gacggcccgt tcgctgcgcc gcagttcgct gacatcgcgg agcacggccc
    18541 acatcgaggc ggtgcagccg tcggcgtcga ggacgggctc gcccgtcatg tgcacggtgc
    18601 gcacacagcc gtcggtccgc acgatccgga actcgccgtc gatcggcttc ccgtcgatca
    18661 gacagtccgt caccatcgtc tggaggacgg gctggtcgtc gacgaagacc atcgtgggca
    18721 tctcgtccag tgacatcggg ccgttctcgc gcgtgcgtcc gaagatctgg aacagctctt
    18781 cggaccagct gacctcgtcg gtcaggaggt tccactcggc gctgccgacg cgggacagca
    18841 gggagccggt gcgctgcggg gcgacctcgc cgtacgcggt gccgggggcg gtggggagcg
    18901 aggtgtcggg tgcggtctcc gccggctcct cggtgacgag ctgctcgggg acacccgccc
    18961 ggagctggcc caagtgggct cccaggtcgt ccagttggtg aacggccagg tcgcacaggg
    19021 cacgctgcca gcgctgctgg gggtcgtcgt cgttcaccac ggcttcccgg cgcacggcga
    19081 cgagctcgcc gcgcaggcgg cgggtctgcg agatcagcgc gtccaccgcg cccggctccg
    19141 gctgctgggc ggggtgatcc gcgaacagtg gggacggcat gtcgtactcc gatacaggcg
    19201 cggcacggcc aggccaggtg gggaagtgag gcccggatac gactgtggca cagcgtggga
    19261 cgacccgtaa gggatttggc aacactcgat ccggtggtgc ttccggcata tgtcaaaggc
    19321 ccagcgatta tcggccaggg cgcgacgggt tacggttccg gggtggtgaa cgacgaggga
    19381 ttcggcccgg tgagcacgcg cacggcggtc acgggcgggg cgactacggg gacgggggcg
    19441 ggggcgggag agagcgcgac gggagcctcc ggtacggcag ttacgcatgt gacggagggg
    19501 acgcgtacga gggggacgga agccgcccgg gcgaccccgg cggcgggtac gacgggtgcg
    19561 aagcctcagg ccccttccgc cgctccggca acagccgcca ccgccaacgc cgtcggcacc
    19621 gccaccggca ccgcctttct gctcgccgcg gcccccgccg ggcgcgggcg cgccatggac
    19681 gccgcgtccg tactgccggt cctcgccgcc gtcccgcccg gagtcctcac cggaacgggc
    19741 accgccaccc tcgtcgaact cgccgatccg ctcgacccgc agaccgtcct cacccgcctg
    19801 cgcgccgccg cggcgagccc cggtccgctc gtgctctgcc tcgccggaca gctccacctc
    19861 gaccgcaggc agcaactccc ccacctcgcg ctcgcccgca ccaccccggc gaccctccgc
    19921 tacacggccc tgccctggca ctggctcggc gccgaactcg ccgcccgcgc acccggcacc
    19981 acgacggtcg tcgcggacct cgcggcggac cccgccgtct gtgaacgcct caccaccacg
    20041 ccgggcttcc tgcacctcgg gcccgggccg accctctacg gcagagtgac ccccgccccg
    20101 cgcaggggcg aactcctcgc ccccgcctat ctgcggtcct gggcggagct ctggcgctcc
    20161 ggcgcccgcc tcccgtacgc cacgctccac gccgagtccg ccgcccgggc ggccggtgcc
    20221 acgccggagg ccttcctcct ggcgcccgcc ccggttcccg caccggtcgc ggaccaggac
    20281 ccgcaccccg cgatcctggc cgccgcgacg gccgggcgcc acggcgaggc ggccgcggtg
    20341 gcagcggcct gggagcgcga ggccctgcgc cgccacgggc cccgctccgc ggaggccgtc
    20401 cactggaccg aggtccgggc cgacctcgcc cgcctcgccg gggagcccgc ccgcagctgc
    20461 gaactctggc tctccgcggc cgaggcccgg ctcgcgctgg ggcagcgcac ggacgacccc
    20521 gacgtcgagg gagccgtgga ccgggcccac caccagtggg aacggatcgt cgaccgggca
    20581 cgggcccgcg ctctcggccc ggtgctcatc accctgcgac agcgggtccc gggccgccgg
    20641 cccggagcac tggcggcctt gaagcgacgc atggctgact gaagcccgcc aagggacgcc
    20701 tggggcggac tagcccgcca ggagccccgt acacgatcgc cccgcacgaa aggccctcgc
    20761 gtgacctcgc tcgccaccac ccagcgttcg ctcgccgacc cgtccgtgca ccatccgctc
    20821 tggcccccgc tcaccgaggg ctgccccatc acctcgaccg acgaggtcgc ccaccccctc
    20881 gacatcgact acgcctacga cgaggtgccc gccgacctgt tcgcgcgccc cgccgcccac
    20941 ggcctggaac ggtggtcccc gctccttccc ccactggcgg cgccggggct cggcgaaggc
    21001 aacaccccgc tggtcgaact ccccgacggc gtctggatca aggacgagtc ccgcaatccg
    21061 acgtggagcc acaaggaccg cctcaaccgg gtcgcgatca gcgccgcggt cgcctccgga
    21121 gccctcggcg tcgtcgtctc ctcctcgggg aaccacggcg cggccgccgc cgcgtacgcg
    21181 gcccgtgccg gactgccctg cgccgtgttc accgccccgg acgccccgcc cgccgtggcc
    21241 tcccacctcc gcgcctacgg agcgacggtg ctgaccctcc cgtacgagtc ggtccggccc
    21301 ctgatgcggc ggatcgtcga cgagctcggc ttccagaacg tcagcagcgt cacggacacc
    21361 gcccacaccg gacacccctt cgggcccgag gggtacaaga cgatcgcgta cgagatcgcc
    21421 ctcgacctcg gccgcgcgcc cgccgccgtc catgtgccca ccggatacgg cgagttgctg
    21481 ttcggcgtgg ccaagggctt ccaggagctc gtacggctcg gggtcaccga ctccgtgccc
    21541 cgcctgtacg ccacggagcc cgccgcggcc ggcgccctcg cggaggcgct ccgcaccggc
    21601 gcgcccgtcg cgcgggtccc ggtgggcccg accaccgcgt acgccatcga ctgcgaggtc
    21661 aacagctacc gcggtgtact cgccgtccgt gcgaccggag gcgcggcccg cacggtgacg
    21721 gacgctcaga tggctgcggc ccaagacgag ttggccgcgc aggggttgtg gtgcgagacc
    21781 tcggcggcgg cgggcctcgc cggactgcgt gcccacgggc cgcgcgagga cgagggcccg
    21841 gtggtgtgcg tggtcacgtc cagcggctac aaggacgtgg ccaccggaag ggacaccgcc
    21901 gccccgacgg ccgcggactg ggcgacgatc gaggcgtccc tgaaggaggc gcgggggcgc
    21961 tgaggcggcc ggggcgggag gaacccgact agggggcgag gccgctcccg gccgcggccg
    22021 gcaggacgac ccggacgccg aactcgtagg tgccggtcgc ccccgcgatc ccgatgaaca
    22081 gcagggcgaa gttctcctgg ccccgcgccg tcgcgatccc gcccaggtcg agcagcgcgt
    22141 cgtcggtcca gccgaggtcg cggaccagac cgcgcaccac cttcttcgcc tccgtgtcc
//
