MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 42.0 93.0 186.0 8.85e-59
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 45.0 98.8 182.0 4.54e-57
QCT05734.1 Tri1 BGC0001983.3 other:other 47.0 93.0 180.0 1.54e-56
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 43.0 92.6 176.0 1.12e-54
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 42.0 94.2 173.0 8.98e-54
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 45.0 95.5 173.0 3.12e-53
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 45.0 93.4 171.0 8.58e-53
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 46.0 93.0 171.0 1.66e-52
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 45.0 96.7 169.0 3.33e-52
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 45.0 93.0 169.0 5.11e-52
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 44.0 92.6 168.0 1.22e-51
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 42.0 95.1 167.0 1.58e-51
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 41.0 92.6 167.0 1.63e-51
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 44.0 91.8 166.0 6.89e-51
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 44.0 91.8 166.0 6.89e-51
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 42.0 92.6 162.0 1.95e-49
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 45.0 92.2 162.0 2.92e-49
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 44.0 94.7 161.0 8.91e-49
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 37.0 92.6 159.0 3.19e-48
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 45.0 93.0 160.0 5.06e-48
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 41.0 93.8 154.0 3.81e-46
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 39.0 99.2 154.0 5.59e-46
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 38.0 92.2 153.0 9.81e-46
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 37.0 93.8 153.0 1.16e-45
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 42.0 91.8 150.0 4.81e-45
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 43.0 91.8 150.0 6.57e-45
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 42.0 91.4 150.0 9.02e-45
AVO00817.1 May18 BGC0001661.5 PKS 42.0 93.8 149.0 2.27e-44
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 38.0 93.0 148.0 6.87e-44
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 37.0 95.1 147.0 1.59e-43
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 41.0 94.2 147.0 1.8e-43
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 40.0 92.2 149.0 2.36e-43
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 40.0 95.9 146.0 3.95e-43
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 41.0 92.2 146.0 5.89e-43
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 41.0 90.9 146.0 5.89e-43
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 40.0 95.9 146.0 1.03e-42
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 38.0 92.2 144.0 3.94e-42
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 37.0 91.8 143.0 1.27e-41
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 37.0 91.8 143.0 1.27e-41
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 42.0 86.4 141.0 1.95e-41
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 37.0 94.7 141.0 4.06e-41
ALJ99857.1 FlsR1 BGC0001904.2 PKS:Type II aromatic 42.0 86.4 140.0 5.68e-41
AAL15604.1 Sim1 BGC0000270.5 PKS 38.0 99.2 141.0 6.53e-41
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 38.0 99.2 141.0 6.53e-41
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 39.0 91.8 142.0 6.57e-41
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 37.0 91.8 140.0 1.16e-40
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 40.0 91.8 140.0 1.43e-40
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 38.0 91.8 140.0 2.92e-40
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 38.0 94.2 138.0 5.67e-40
AFI57015.1 QmnRg3 BGC0000133.5 PKS 39.0 92.2 133.0 2.9e-38
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 38.0 98.8 134.0 3.58e-38
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 35.0 93.4 132.0 7.7e-38
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 39.0 96.3 132.0 1.03e-37
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 36.0 95.1 132.0 1.7e-37
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 35.0 93.4 130.0 4.28e-37
ABW71856.1 putative_regulator BGC0000303.5 NRPS:Type I 36.0 97.9 131.0 5.88e-37
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 33.0 93.8 129.0 8.51e-37
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 36.0 92.2 125.0 2.98e-35
ADB02841.1 AzicR3 BGC0000202.5 PKS 36.0 96.7 125.0 6.55e-35
AEA29625.1 Por2 BGC0000409.5 NRPS:Type I 37.0 86.8 124.0 8.76e-35
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 35.0 92.2 123.0 2.38e-34
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 35.0 92.2 123.0 2.38e-34
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 39.0 95.1 122.0 8.12e-34
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 35.0 92.2 121.0 2.1e-33
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 33.0 93.8 117.0 3.43e-32
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 35.0 91.8 116.0 1.37e-31
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 34.0 95.1 112.0 7.21e-30
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 29.0 93.4 107.0 2.86e-28
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 31.0 93.0 106.0 7.9e-28
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 28.0 92.6 105.0 1.7e-27
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 29.0 92.6 105.0 1.7e-27
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 28.0 93.0 103.0 8.41e-27
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 43.0 45.7 97.0 4.07e-25
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 41.0 53.5 91.0 3.19e-22
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 36.0 50.2 82.0 1.11e-17
ABK32284.1 Jer4 BGC0000080.5 PKS 37.0 48.1 79.0 1.07e-16
ABK32252.1 Amb4 BGC0000014.5 PKS 37.0 48.1 79.0 1.46e-16
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 39.0 45.3 79.0 2.44e-16
ADB02831.1 AzicR2 BGC0000202.5 PKS 33.0 68.7 73.0 3.08e-15
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 30.0 89.7 71.0 1.06e-14
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 31.0 73.7 71.0 1.17e-14
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 30.0 88.1 71.0 1.66e-14
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 39.0 51.0 70.0 3.63e-14
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 27.0 85.6 70.0 3.74e-14
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 29.0 64.6 69.0 6.23e-14
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 30.0 85.2 69.0 9.12e-14
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 32.0 75.7 68.0 1.61e-13
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 32.0 85.2 67.0 2.93e-13
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 41.0 46.1 67.0 4.91e-13
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 29.0 68.3 67.0 6.06e-13
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 27.0 93.0 66.0 8.34e-13
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 31.0 68.7 66.0 9.94e-13
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 28.0 68.3 66.0 1.15e-12
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 30.0 86.0 66.0 2.01e-12
CAF05630.1 hypothetical_protein BGC0001053.5 NRPS:Type I+PKS 35.0 46.5 67.0 2.17e-12
BAW35646.1 putative_two-component_system_response_regulator BGC0002356.3 PKS+other:other 28.0 88.1 64.0 4.7e-12
AWC08650.1 putative_two-component_system_response_regulator BGC0001662.4 PKS 28.0 88.1 64.0 6.47e-12
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 32.0 59.7 63.0 8.04e-12
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 33.0 54.3 63.0 1.36e-11
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 26.0 84.8 63.0 1.36e-11
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 26.0 85.2 62.0 2.74e-11
ctg1_orf18 BGC0000053.5 PKS 33.0 54.3 61.0 6.88e-11
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 28.0 95.1 61.0 1e-10
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 30.0 86.0 59.0 3.46e-10
BAW27696.1 regulator BGC0001764.4 NRPS:Type I 26.0 84.8 59.0 3.85e-10
BBD82049.1 LuxR_family_transcriptional_regulator BGC0001920.4 ribosomal:RiPP 29.0 97.1 59.0 4.73e-10
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 26.0 85.6 58.0 6.67e-10
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 28.0 74.5 58.0 8.82e-10
ACI88882.1 AlnR5_two_component_response_regulator BGC0000195.5 PKS:Type II 32.0 51.4 57.0 1.26e-09
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 33.0 46.9 57.0 1.7e-09
ABD65961.1 two-component_system_response_regulator BGC0000341.5 NRPS:Type I 30.0 52.7 57.0 2.22e-09
WP_030193597.1 response_regulator_transcription_factor BGC0002669.2 ribosomal:RiPP 30.0 67.1 56.0 3.71e-09
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 30.0 55.6 56.0 4e-09
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 30.0 55.6 55.0 7.43e-09
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 34.0 49.4 55.0 7.73e-09
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 28.0 58.8 54.0 2.36e-08
ACR33059.1 response_regulator BGC0000495.5 ribosomal:RiPP:Lanthipeptide 27.0 74.9 54.0 2.55e-08
QUQ72355.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 29.0 87.7 54.0 2.63e-08
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 29.0 86.4 54.0 2.99e-08
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 28.0 74.5 52.0 6.53e-08
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 27.0 86.4 52.0 9.27e-08
AKT74265.1 TxnRg4 BGC0002141.3 PKS 29.0 59.7 51.0 1.86e-07
ACX83628.1 putative_two-component_response_regulator BGC0000221.5 PKS 28.0 55.6 50.0 2.22e-07
ATD51275.1 two-component_system_response_regulator BGC0001650.4 NRPS:Type I 34.0 52.3 50.0 2.83e-07
QDQ37907.1 two-component_system_response_regulator BGC0001979.4 PKS 29.0 59.7 49.0 8.6e-07
AFL68048.1 response_regulator_with_CheY-like_receiver_domain_and_winged-helix_DNA-binding_domain BGC0001524.3 NRPS:Type I+PKS 33.0 41.6 49.0 1.29e-06