LOCUS       NZ_LIWC01000008        23717 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Amycolatopsis sp. CB00013 scaffold8, whole genome shotgun sequence.
ACCESSION   NZ_LIWC01000008
VERSION     NZ_LIWC01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Amycolatopsis sp. CB00013
  ORGANISM  Amycolatopsis sp. CB00013
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 356912)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356912)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905755.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:05:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,488
            CDSs (total)                      :: 8,430
            Genes (coding)                    :: 8,383
            CDSs (with protein)               :: 8,383
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 17 of 47
            Pseudo Genes (incomplete)         :: 38 of 47
            Pseudo Genes (internal stop)      :: 1 of 47
            Pseudo Genes (multiple problems)  :: 9 of 47
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 119512
            Orig. end                         :: 143229
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIWC01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23717
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23717
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23717
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13717]"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13717
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(240..794)
                     /locus_tag="AMK34_RS40195"
                     /old_locus_tag="AMK34_39910"
     CDS             complement(240..794)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336203.1"
                     /locus_tag="AMK34_RS40195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39910"
                     /product="isochorismatase family protein"
                     /protein_id="WP_073849046.1"
                     /transl_table=11
                     /translation="MTTLDNRPNTALLVVDVQNAVVDEGYERDAVVAKIGGLVGRARRE
                     GVPVVWVQHSDDGLVRGSEEWRIVGELNQEEAEPVVEKSYGDSFEDTDLERVLAERGVG
                     RLVVVGAETDACIRSTLHGAIVRGYDATLVGDAHTTVDKTEWGGIAPELVIAHTNLYWR
                     YQAAPGRKGGTVMSEDVDFSG"
     gene            complement(862..1689)
                     /locus_tag="AMK34_RS40200"
                     /old_locus_tag="AMK34_39915"
     CDS             complement(862..1689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630552.1"
                     /locus_tag="AMK34_RS40200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39915"
                     /product="acetylxylan esterase"
                     /protein_id="WP_038522741.1"
                     /transl_table=11
                     /translation="MGRLRARTLIAGMVALATVGLAPAATAATGIDTRWSEPGPYAVTV
                     EALDSAHTVYRPSRLERHPVILWGNGTGANPKTYDGLLRHLASHGFVVAAADTPNAGSG
                     QEMLAGATTLIAENSRPGSRYEGKIDTAHIGATGHSQGGGGAIAAGADARVTTTIPIEP
                     GPQGSATALKGPSFFLGGQFDTIVIPGLLVIPRYRLADQVPAIYGELRGATHFTPVGDG
                     GGFRGAITAWFRFWLSGDERARAEFFGPSCGLCRDGAWSAVQRNTKALAVPGA"
     gene            complement(1828..2379)
                     /locus_tag="AMK34_RS40205"
                     /old_locus_tag="AMK34_39920"
     CDS             complement(1828..2379)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK34_RS40205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK34_39920"
                     /product="hypothetical protein"
                     /protein_id="WP_143202769.1"
                     /transl_table=11
                     /translation="MIDNGRFAMRFRSMTASVLLGCALCVAPAALGAGPSSLAIQPCPE
                     VNDPPDYTISNGAKAWMKTNLRSDYLRGPGTITYNKTTTSSVNASITGTTSAEAGVIFA
                     KASVSLAVSVGASYSKADSWSYAATVPAGKTLRLQQYKEGRSFTVQKYRIVPPCKVKYL
                     WKKNAVAPVKSPSYLWQLIG"
     gene            complement(2460..3641)
                     /locus_tag="AMK34_RS40210"
                     /old_locus_tag="AMK34_39925"
     CDS             complement(2460..3641)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (20-385). E-value: 6.5e-51.
                     Score: 165.3. Matches aSDomain:
                     nrpspksdomains_AMK34_RS40210_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032870.1"
                     /locus_tag="AMK34_RS40210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39925"
                     /product="cysteine desulfurase-like protein"
                     /protein_id="WP_073849047.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2.4e-49, bitscore:
                     162.6, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.3e-06,
                     bitscore: 22.2, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.7e-06, bitscore:
                     21.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDVAALRLHFPSLADGTAFFDGPAGTQTPRPVADAIAGTLTGP
                     LSNRGKVSPSELNAENAVSGFRDAYADFLGVPAEGVVHGRSATQLTYDFSRHLAKSWRE
                     GDEIVVSRLDHDANVRPWVQAAERAGMTVRWLDIDPETTELDLDSLVLTERTRLVAVTA
                     ASNVLGTKPQIRRIADLAHDAGALVFVDGVHYAAHELVDVPALGADFFVCSPYKFLGPH
                     CGVLGASPALLETVEPDKLVPSPDSVPERFEFGTLPYEMLAGATAAVDFLAALDPGAGG
                     SRRERLANSMNSLHEHESTLRARLEEGLGDAVTVHCKAADRTPTVLMGLGGREREAQRH
                     LAERNVVAPAGSFYAHEVFAALKLEDPALRVGLAPYTSIDDVDRLLDGLSTFG"
     aSDomain        complement(2487..3581)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK34_RS40210_Aminotran_5.1"
                     /evalue="6.50E-51"
                     /label="AMK34_RS40210_Aminotran_5.1"
                     /locus_tag="AMK34_RS40210"
                     /protein_end="385"
                     /protein_start="20"
                     /score="165.3"
                     /tool="antismash"
                     /translation="FFDGPAGTQTPRPVADAIAGTLTGPLSNRGKVSPSELNAENAVSG
                     FRDAYADFLGVPAEGVVHGRSATQLTYDFSRHLAKSWREGDEIVVSRLDHDANVRPWVQ
                     AAERAGMTVRWLDIDPETTELDLDSLVLTERTRLVAVTAASNVLGTKPQIRRIADLAHD
                     AGALVFVDGVHYAAHELVDVPALGADFFVCSPYKFLGPHCGVLGASPALLETVEPDKLV
                     PSPDSVPERFEFGTLPYEMLAGATAAVDFLAALDPGAGGSRRERLANSMNSLHEHESTL
                     RARLEEGLGDAVTVHCKAADRTPTVLMGLGGREREAQRHLAERNVVAPAGSFYAHEVFA
                     ALKLEDPALRVGLAPYTSIDDVDRL"
     gene            complement(3722..5707)
                     /locus_tag="AMK34_RS40215"
                     /old_locus_tag="AMK34_39930"
     CDS             complement(3722..5707)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032871.1"
                     /locus_tag="AMK34_RS40215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39930"
                     /product="peptidase S8/S53 subtilisin kexin sedolisin"
                     /protein_id="WP_073849048.1"
                     /transl_table=11
                     /translation="MKLRSITKRMFVLGLLTVLGTTGATSVATAEPQAPPTDVNATGKP
                     RGGWEPVGPNSVGGMLAVSPAGLAMMQPSPPALWLSGDRGASWSVRRGLPQDTSIQGFF
                     VDPANPDRMLAVGNKPAGFLGEWRGMLVRTTDRGQTWETLREWYPDGAFGMATDPTGRV
                     VVVQNMDSLSVSTDGGEHWNDVPRTWPREGNASPVGALKLTMVGDDAYLTTVLPEYALW
                     VVRGVSGKEPQAELVYRANGEINQVASDGKRFVVTVGPELHGSTDGGKTWTVLRRDPGE
                     QTLREPRFLGGRLYVSTYNDIDVSADFGRTWSRKPVPAAGEGVSDMIDLPAGPGKPATT
                     LISSLYRGVYADEGKRGYQQIGVPGESIRDLVTTGNLLRESVVAAGVQEIYNTPLPRGK
                     VAAADRVWQSHPADRLHEDARLSVSPSRPDVVWQVTRNGFSLDVLRSGDGGRTWEFAAK
                     AKEGLPRAIFAHPADPNRVLVSAFAPSGYVLYRSNDAGKTWEKLATDNGFIAFAGDPWN
                     PDRVWGGDSDGLSRSDDGGKTWTHVTSQPVSAISISRWGGGRVLIGGAGIHLSEDGGKT
                     FRRVFDGEDPREISRILPHPFDFRVWFASNATGGGVLRSTDFGRTWSPVPGALPDSRVL
                     SLAVSADGRYLFAGTAQSGAYRLTLY"
     misc_feature    5674..5687
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.82"
                     /tool="antismash"
     misc_feature    complement(5674..5687)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.27"
                     /tool="antismash"
     misc_feature    5692..5706
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.27"
                     /tool="antismash"
     gene            complement(5824..6627)
                     /locus_tag="AMK34_RS40220"
                     /old_locus_tag="AMK34_39935"
     CDS             complement(5824..6627)
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032872.1"
                     /locus_tag="AMK34_RS40220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39935"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_073849049.1"
                     /transl_table=11
                     /translation="MLIEISVLLGFGCLSGVTTVLFGFGGGFITVPVVYAFALADPEHA
                     QDAMHVAVATSTAVMVVNAGSATLAQLRTGRLRRDYLWPLIAFIGLGAVLGSFTATVAD
                     EGVLRWLFVAYLALTIADSVARKGFVSRREDDGPRALGGVTTIAGGTGIGAVASFLGVG
                     GSVLTVPLMRRKGLPMADATALANPLSLPVAVIGTAVYAFAATGTSSGGAHVGYVDLVA
                     AGALLCGSLPTIAVTRRVVGRIPDRAHAIAYLALLAAALIAIVIR"
     gene            6719..7492
                     /locus_tag="AMK34_RS40225"
                     /old_locus_tag="AMK34_39940"
     CDS             6719..7492
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630557.1"
                     /locus_tag="AMK34_RS40225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39940"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_038509915.1"
                     /transl_table=11
                     /translation="MRDIPIDEVDHLDRAVVAIRTDYPPGHRILPHRHRRAQFLYSATG
                     SMRVETADGTWTIPTRRAVLVPPETVHQVFTTTVSTRSLYIEPKAVPWFPRRCQVVEVS
                     ALLRELLNEAVGVPELYTARGRDAAVIGLTLHEIRRSAPVRLDLPLPKHERLRAQCESF
                     LDAPDIHDPASEWANRLHVSERTLNRLFTAETGMGFARWRQRACVLHSLSLLSDGLPIA
                     AIAASLGYESPAAFSTMFTRLLGTSPRDYRAASAL"
     gene            complement(7636..8451)
                     /locus_tag="AMK34_RS40230"
                     /old_locus_tag="AMK34_39945"
     CDS             complement(7636..8451)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336209.1"
                     /locus_tag="AMK34_RS40230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39945"
                     /product="DUF1206 domain-containing protein"
                     /protein_id="WP_083650150.1"
                     /transl_table=11
                     /translation="MSTTKARQVRHNKAVQVLGRIGMGCYGLVYLLIGYLAARVAVGGG
                     GQEADGRGAITEVGSTPAGGVLLWVLAVGLVAYGLWQGLLAAVGYTWIDKQRTRTVKRV
                     TSGVRCLVGISLGVYAAKVALGAGEQGSGDQKQQEFTAWLLGLPAGPFLVTVVAVIVFG
                     VAVGSAVKGIRRTFDQDLDLAKLPSGTRRWVERLGRIGYVARGVVFGVVSVLVGYAALT
                     HDPSRSGGLDAALRTLAAQPFGTVLLIVVAVGVAAFGVYCVGAARAQRG"
     gene            complement(8544..8954)
                     /locus_tag="AMK34_RS40235"
                     /old_locus_tag="AMK34_39950"
     CDS             complement(8544..8954)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336210.1"
                     /locus_tag="AMK34_RS40235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39950"
                     /product="hypothetical protein"
                     /protein_id="WP_073849051.1"
                     /transl_table=11
                     /translation="MYCLRAVIVTESARRRVLDSLEGARLVPLGQDLSLMPVAETRFDT
                     GPLAECSEHGAVAYVEAEYFGGAGTQFAQVWEGGETVLGPLQVDEDEPDPADGSPISQA
                     LRRLGVLKGDHFDEFDAVGLGRHRDTDDWLSA"
     gene            9067..9642
                     /locus_tag="AMK34_RS40240"
                     /old_locus_tag="AMK34_39955"
     CDS             9067..9642
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336211.1"
                     /locus_tag="AMK34_RS40240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39955"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_073849052.1"
                     /transl_table=11
                     /translation="MTATYTFDVFSSLDGYGAHTGDWGGYWGKQGPEFLEHRLALYSEK
                     QRMVFGASTFRTNMEMLNAEIPDVEALDPWVSRLKHLPATVVSTTLREPLAWPDATVVS
                     GDAVDVVARLKEESEVPLRSHGSLSMNRALMAAGLVDRVQVTVFPVITGKTGADAIFRG
                     AADFDLELLESRTFDGRVQELVYRPAPH"
     gene            complement(9675..9968)
                     /locus_tag="AMK34_RS40245"
                     /old_locus_tag="AMK34_39960"
     CDS             complement(9675..9968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032876.1"
                     /locus_tag="AMK34_RS40245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39960"
                     /product="hypothetical protein"
                     /protein_id="WP_051972394.1"
                     /transl_table=11
                     /translation="MYAPSLLDPAAEELKLADVLGHGATGVAREARTLLGERFSSVTFM
                     YVLMRAFEVEYTAARDASRWHEFHGGPYALSDADLEALLAPWLGAPAASITA"
     gene            complement(10001..11107)
                     /gene="rlmN"
                     /locus_tag="AMK34_RS40250"
                     /old_locus_tag="AMK34_39965"
     CDS             complement(10001..11107)
                     /EC_number="2.1.1.192"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmN"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336213.1"
                     /locus_tag="AMK34_RS40250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39965"
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="WP_038509905.1"
                     /sec_met_domain="PF04055 (E-value: 7.8e-24, bitscore: 79.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALPLVFDAPKRGLPPRHLADLTAAERAAAVAELGEKPFRAKQL
                     SNHYFSRLTVNPEEMTDIPAASREKLVGDLMPTLLTEIKALACDDGTTRKTLWRAHDGT
                     LLESVLMRYPDRATLCISSQAGCGMACPFCATGQGGLDRNLSTAEIVDQVRSAAAVMRD
                     GQMPGGPGRLSNIVFMGMGEPLANYKRVVAAVRRITDPSPEGLGIGQRSVTVSTVGLAP
                     AIRKLADEKMQVRLAVSLHTPDDELRDTLVPVNERWSVDEVLSAARYYADTSGRRVSIE
                     YALIRDVNDQPWRAELLAKRLRQHLGQLVHVNVIPLNPTPGSKWDASPKPVEREFVRLV
                     NAGGVACTVRDTRGQEIAAACGQLAAEN"
     misc_feature    complement(11286..11299)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.19"
                     /tool="antismash"
     gene            11327..11461
                     /locus_tag="AMK34_RS43820"
     CDS             11327..11461
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004561011.1"
                     /locus_tag="AMK34_RS43820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_257485210.1"
                     /transl_table=11
                     /translation="MISTFERPAAVVVHNRAVVHNRAVVHNRAVVHNRAVVHNRSAAK"
     gene            11549..13717
                     /locus_tag="AMK34_RS40255"
                     /old_locus_tag="AMK34_39970"
     CDS             11549..13717
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226216.1"
                     /locus_tag="AMK34_RS40255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39970"
                     /product="YcaO-like family protein"
                     /protein_id="WP_073849053.1"
                     /sec_met_domain="TIGR03604 (E-value: 3.8e-80, bitscore:
                     263.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 6e-61, bitscore: 201.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSEEVRPRLDGIEITDLEPELCFLVTPNGGQFYIAAPTGEFRAW
                     ASRCDGTRTRSELLDGMDPDYAEMMDILEADGCLRPDRGTEADDVTTTAIVLTGSPVLI
                     EPLAEILEAVGYASVETVPYFHDLSEMDLNNTVVVSAFDHPAYTELIALDALCAGSGVR
                     WLPLRRERGRVIAGPAIAPGGIDFADVVARRRSAAQDPRVVEAFLSAPSDSTPLRPGDA
                     RWALTTLAVHLGRWLSGGRTAMTTGEIELNPADLTEIRRPILPVPDRARTVPTVTDPEL
                     LVDDQTGIVTGVGEIPPTPGMPARLRVCAVDVADMRRVTNWPNDRQAFGTSWYDFDLAR
                     QSAIGEAVERYCGSWLAPEREVCFGSYNQFLRYGVPAVDPRRLNLYSASQYRSPGFPFA
                     PLTRDTECSWVEGFSHTTGEPVWVPAFLFSNERRPGEAHFADPLIAGLASGTTEEHAVT
                     SGLEEVLERDTTMLWWANTPRLGRLSIPDEIRSLIADATDDYEVALIHLDNEFDVPVIA
                     AAVFDRVKRWLSIGFAARPDALEAAKKALAEGFTLQHTCHALDDERELSGMRRDLPHLG
                     NLKPHRADRRYLDSYRHDFADVADLLCQQQIYLDPRAAKRVKPWVMDLPSRDWADLPAL
                     GERRLKAYQARVEGRGFEVISVDLTTCDVAAAGFHAAHTLVPGLVSNFPAGSPLWGNGR
                     IADAAVELGWRDEPLAEHELNVFPLPHA"
     misc_feature    complement(11585..11599)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    11591..11605
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            13717..14925
                     /locus_tag="AMK34_RS40260"
                     /old_locus_tag="AMK34_39975"
     CDS             13717..14925
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226215.1"
                     /locus_tag="AMK34_RS40260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39975"
                     /product="MFS transporter"
                     /protein_id="WP_038509901.1"
                     /transl_table=11
                     /translation="MATADLLGLPSTRGRFPLIAAQSVDALGTGLFLPFAVVYFHAAKG
                     LSLTAVGAALSIAALIALPSGPLAGRLIDRFGPGRMVITANLIRAVTFTGYVFADEAWH
                     LVVLAAVTFWGEGMFWPSTGALVAQVADDGQRARWYAMERALRNVGIGLGGLLGAAMVA
                     WGGTAGYTAIVLVNAASFVVAAVLVASWRAPAGTPRETEPEAAPAGGYRKVFADRIFRG
                     VLVTVFVFALCDLALTVLLSAYVLDGLKLPAWQPGVLFTVNTVLIVLAQTVVSRRVERR
                     SMPRTLRLSAAVWAISFALFALVPTGESTAAFLVLALAMIVFTCAELLQAPTSSALTVA
                     IAPARLRGRYLGLEELVWSAARVIAPAMFTWLLSHGPALPWLVLIGFCGVAIVVLGRLN
                     RAL"
     gene            14915..15382
                     /locus_tag="AMK34_RS40265"
                     /old_locus_tag="AMK34_39980"
     CDS             14915..15382
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559290.1"
                     /locus_tag="AMK34_RS40265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39980"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073849054.1"
                     /transl_table=11
                     /translation="MRSELDDVYCRVYREPPYLEGEDDVARFGVLFAEHAALPGFAMTT
                     VREAGTIGGFAYGVRREAGWWPGRATAPAPSWLDGEELFYVYELALVPELRGRGLGRAL
                     LDDLLKERPERFAVLASRVEAPARRLYHRWGWRKVGAFDSGGIDLLALALS"
     misc_feature    15429..15447
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            15471..16082
                     /locus_tag="AMK34_RS40270"
                     /old_locus_tag="AMK34_39985"
     CDS             15471..16082
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032878.1"
                     /locus_tag="AMK34_RS40270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39985"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_038522736.1"
                     /transl_table=11
                     /translation="MRRRPFPPEHGRPAFGPWARGGFGDFPPGPGGPGHRHRHGRRGGP
                     GGRRGKRGDVRAAILALLSEQPRHGYEIIREIGERSGGFWKPSPGSVYPTLQMLADEGL
                     VISKDENGKKLFELTESGRAAAEQQDAVPPWEQIAHDVDPVEVNLRKAGATLAAAVAQV
                     MHAGSESQQARTVDVLNEARRTIYGILGEAEDTAPDEDTE"
     gene            complement(16028..16867)
                     /locus_tag="AMK34_RS40275"
                     /old_locus_tag="AMK34_39990"
     CDS             complement(16028..16867)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336215.1"
                     /locus_tag="AMK34_RS40275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39990"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_073849055.1"
                     /sec_met_domain="PCMT (E-value: 2.3e-06, bitscore: 21.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWFPRALSSSRRGGEEVLPSPNIWYYQKAYEVENRAQDVDDEIW
                     RVLTGARDWSGADVLDIGCGDGFHLPRFAATARSVVGVEPHEPLVRDARNRVERLANVE
                     VRQGRAQRLPLPDAAFDVVHARTAYFFGPGCEPGLREAERVLRPGGLMMIVDLDVTSEP
                     YGRWMRLDLPHYDPPGVEKFFARQGFDCRKVMTRWLFEDAAAMEAVLKIEFSAPVAAKA
                     IAEVRRLNEVSSGAGEKQVTLPVGYRVHTRAKPTGLVVPDHSVSSSGAVSSASPRMP"
     gene            16983..17828
                     /locus_tag="AMK34_RS40280"
                     /old_locus_tag="AMK34_39995"
     CDS             16983..17828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630575.1"
                     /locus_tag="AMK34_RS40280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_39995"
                     /product="VOC family protein"
                     /protein_id="WP_038509894.1"
                     /transl_table=11
                     /translation="MSLGSAAHTSVIPSGIPCWIELACRDEAAAQAFYSGLFDWEFTVQ
                     RDPATPTGRYSIATLNGVPTGGLYRAGADGPSGWSVHISVSQAAAAAEWVDSLGGRVTL
                     GPMAIPHRGSIVHAIDACGAHVVFWEPPATWEFATGVPNTFSGADLNTHDGAAADHFYC
                     RLFDYTSHQIGDGASLDYAEWLIEHEPVLYRYVMGSEYRPDTPPHWMVYLALDPARGAD
                     AAAGQALMLGGAVVVQPYDTPYGRMAILADPDGSVFAVIDHSRAVEGWGTAEVDDPYDD
                     "
     gene            complement(17841..18737)
                     /locus_tag="AMK34_RS40285"
                     /old_locus_tag="AMK34_40000"
     CDS             complement(17841..18737)
                     /EC_number="2.7.7.41"
                     /GO_function="GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336218.1"
                     /locus_tag="AMK34_RS40285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_40000"
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="WP_037342324.1"
                     /transl_table=11
                     /translation="MSQVSEEREDRVENPEPVPAEKPEPAQKVSRAGRNLPAAIGVGLL
                     LGAAIVTSLLTVRFLFIGIIAIAIAVGTIELAGALKRAAGIRIALVPVLVGGQAMIWLA
                     WPYGREGALTAFVLTVLVCLLWRLPGGADGYLRDISASVFAAAYIPLFGAFAAMLVPPE
                     DGVGRVLAFMIGVVASDTGGYIAGVLGGKHPMAPTISPKKTWEGFAGSLVAGVVAGALT
                     LSLLLDGHAWQGVLFGAAIVCTATLGDLVESLIKRDLGVKDMGNMLPGHGGLMDRLDSL
                     LPSAVVSWLLLSAFVPV"
     gene            complement(18737..19294)
                     /gene="frr"
                     /locus_tag="AMK34_RS40290"
                     /old_locus_tag="AMK34_40005"
     CDS             complement(18737..19294)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="frr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943637.1"
                     /locus_tag="AMK34_RS40290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_40005"
                     /product="ribosome recycling factor"
                     /protein_id="WP_038509892.1"
                     /transl_table=11
                     /translation="MIDETLLDAEEKMEKAVSVAKEDLSSVRTGRAHPGMFSRVVVDYY
                     GAPTPLNQLAGVNIPEARMALIKPYDQTSLNAIEKAIRESDLGVNPSNDGNVIRIVIPQ
                     LTEERRKEMVKVAKSKGEDARVSIRSVRRKAKEELDRIKKDGEAGEDEVVHAEKELQNL
                     TDTYTHKVDELVKHKEAELLEV"
     gene            complement(19346..20089)
                     /gene="pyrH"
                     /locus_tag="AMK34_RS40295"
                     /old_locus_tag="AMK34_40010"
     CDS             complement(19346..20089)
                     /EC_number="2.7.4.22"
                     /GO_function="GO:0033862 - UMP kinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223864.1"
                     /locus_tag="AMK34_RS40295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_40010"
                     /product="UMP kinase"
                     /protein_id="WP_005154669.1"
                     /transl_table=11
                     /translation="MGVRVEGGYRRVLLKLGGEMFGGGSIGVDPDVVHSVAQQIADVAR
                     TGVQIAVVIGGGNYFRGAELSQRGMDRDRADYMAMLGTVMNCLALQDFLEKEGLPTRVQ
                     TAITMGQVAEPYIPRRAERHLEKGRVVIFGAGVGMPYFSTDTAAAQRALELGCEAVLMA
                     KAVDGVYTADPKSDPTAEMFHEISHREVLERDLKVADATAFSLCMDNNMPIIVFNLLTE
                     GNIARAVSGERIGTLVDTPADGVPA"
     gene            complement(20183..21007)
                     /gene="tsf"
                     /locus_tag="AMK34_RS40300"
                     /old_locus_tag="AMK34_40015"
     CDS             complement(20183..21007)
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tsf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074497.1"
                     /locus_tag="AMK34_RS40300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_40015"
                     /product="translation elongation factor Ts"
                     /protein_id="WP_038509890.1"
                     /transl_table=11
                     /translation="MANYTAADVKRLRELTGSGMMNCKKALEENDGDFDKAVEFLRIKG
                     AKDVGKRAERATAEGLVAGDGGVLIELDSETDFVAKNEDFQALAAKIVEVAKAEKTSDV
                     EKLKAASLDGKTVEEQVQELAARIGEKLELRRVAAYEGTTTTYLHRRGADLPPAVGVLI
                     EYTGEGEAAAEAARGAAMQVAALKAKYLTREEVPAEIVENERRVAEATAREEGKPEQAM
                     PKIIEGKVNAYYKDNVLLEQPSVKDNKKTVKALLDEAGVAVSRFARFEVGQA"
     gene            complement(21100..21972)
                     /gene="rpsB"
                     /locus_tag="AMK34_RS40305"
                     /old_locus_tag="AMK34_40020"
     CDS             complement(21100..21972)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032886.1"
                     /locus_tag="AMK34_RS40305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_40020"
                     /product="30S ribosomal protein S2"
                     /protein_id="WP_007032886.1"
                     /transl_table=11
                     /translation="MAVVTMKQLLDSGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQQ
                     TLTYIDRAYEFIKETVAHGGTIMFVGTKKQAQEAIASEASRVGMPYVNQRWLGGMLTNF
                     QTVHKRLLRLKELESQEQTGGFAGLTKREILTLTREKDKLEKTLGGIRDMAKVPSIVWI
                     VDTKKEHIAVGEARKLNIPVVAILDTNCDPDEVDYPIPGNDDAIRSAALLTKVVAEAAA
                     AGLMARSSRNGSSADAKPEAGVATDEPLAEWEKELLAGSETAAADAKEAAAATDAPTEA
                     PAEQATASS"
     misc_feature    22152..22166
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            22355..22960
                     /locus_tag="AMK34_RS40310"
                     /old_locus_tag="AMK34_40025"
     CDS             22355..22960
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016336223.1"
                     /locus_tag="AMK34_RS40310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_40025"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_073849056.1"
                     /transl_table=11
                     /translation="MTMTTCSRPVTRHSFALDRAGGRHRRPGRPRRLPRLAILATLLAI
                     FASAAMPGTARGAPSPQGRLSWPLSPVPSVTRYFEPPSTPYGPGHRGIDLASAPGTNVL
                     AAAEGVVMFAGQVAGRGVVSIDHDGGLRTTYQPLALTVTAGDQVYRGQVLGTLAAGHPG
                     CPEPACLHFGVRRGEEYVDPLALIGEPSEIRLKPWEGD"
     misc_feature    complement(23532..23546)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
ORIGIN
        1 cgaccacccg actccagcct ggagatctcc tcgtcctgca caccgaaggc ctctcggagg
       61 cgcgttccgc cgacggcgca cggttctctc tcgccgggag cctggacgcc aacgccggac
      121 acgtaccgcc cgagatcgcc cgtcgcgtgc tgcaggcggc gaagtcccac tgccacaaca
      181 ctttcgccgg tgacgccggt ctgctactcg ctcactggcc gggaacgccg tgaagccgct
      241 cagccactga aatcgacgtc ttcgctcatc accgtccctc cctttcggcc cggcgcggcc
      301 tgataccgcc agtacaggtt cgtgtgcgcg atgaccagtt ccggcgcgat tccgccccac
      361 tcggtcttgt ccacggtcgt gtgcgcgtcg ccgaccagcg tcgcgtcgta cccgcggacg
      421 atggcgccgt gcagcgtcga acggatgcag gcgtcggtct cggccccgac gaccacgagc
      481 cgtccgacac cgcgttcggc cagcaccctc tccaggtcgg tgtcctcgaa cgagtcaccg
      541 taggactttt cgacgaccgg ctcggcttcc tcctggttca gttcgccgac gatgcgccat
      601 tcttcgcttc ctcgcacgag cccgtcgtcg gagtgctgca cccagacgac cgggacgcct
      661 tcccgccgtg ccctgccgac gagcccgccg atcttcgcga ccacggcgtc gcgctcgtag
      721 ccctcgtcga cgacggcgtt ctggacgtcg acgacgagga gcgcggtgtt cggccggttg
      781 tcgagagtgg tcatgacggg tatccctcca ggtcaggctg ctgaggcaga ccctagcccc
      841 ggccaccgac aagaacggcg atcaagctcc cggaacggcc agcgccttcg tgttgcgctg
      901 gacagcggac cacgcgccgt cccggcacaa tccgcaggac gggccgaaga actccgcgcg
      961 ggcccgctcg tcaccggaaa gccagaaccg gaaccacgcc gtgatggcgc cgcggaaccc
     1021 gcctccgtcg ccgacgggcg tgaagtgggt cgcgccgcgg agttcgccgt agatcgcggg
     1081 gacctggtcc gcgaggcggt agcgcgggat gaccagcagc ccggggatga cgatggtgtc
     1141 gaactggccg ccgaggaaga acgaaggacc cttgagtgcc gtggcggagc cctgcggccc
     1201 cggttcgatc gggatcgtgg tggtgacgcg cgcgtcggcg ccggcggcga tcgctccgcc
     1261 gccgccctgg gaatggccgg tggcgccgat gtgcgcggtg tcgatcttcc cctcatagcg
     1321 gctgccggga cgggagttct cggcgatcaa ggtcgtggca ccggccagca tctcctgccc
     1381 cgaaccggcg ttcggggtgt cggccgccgc gacgacgaaa ccgtgggagg ccagatgccg
     1441 cagcaggccg tcataggtct tcgggttcgc gccggtcccg ttgccccaca ggatgaccgg
     1501 atgcctctcc agccgcgaag gccggtacac ggtgtgcgcg ctgtcgaggg cttcgacggt
     1561 caccgcgtag gggcctggtt cgctccaccg ggtgtcgata ccggtcgcgg ccgtcgcggc
     1621 gggtgcgagg ccgacggtgg cgagcgcgac catcccggcg atcagtgtcc gtgcgcgaag
     1681 tctccccatg atggccaccc gtcccgttcc gccaggaccc cgttgcccac ggcgttcctc
     1741 tcagggtgtc ggcccggtca ccgtacgtcc atggggccga tcacaagatc gggcggacga
     1801 gtcttgtgat cggccccaaa gcgagggtca gccgatgagc tgccacaggt agctcggact
     1861 cttcaccggt gcgacggcgt tcttcttcca gaggtacttc accttgcagg gtgggacgat
     1921 gcggtacttc tgcacggtga aggaacggcc ttccttgtac tgctgcagcc gcaacgtctt
     1981 ccccgcgggc acggtcgcgg cgtaggacca ggaatcggcc ttcgagtagc tcgcgccgac
     2041 gctcaccgcc agcgagacac tcgccttcgc gaagatgacg cccgcctcgg cgctggtcgt
     2101 gccggtgatg gacgcgttga ccgacgaggt cgtcgtcttg ttgtaggtga tcgtgcccgg
     2161 cccgcgcagg tagtcactgc gcaggttcgt cttcatccag gccttggcgc cgttcgagat
     2221 cgtgtagtcg ggcggatcgt tgacctcggg acagggctgg atcgcgagcg acgagggccc
     2281 cgccccgagt gccgcgggcg ccacgcacag ggcgcaaccg agaagaacag aagcggtcat
     2341 cgaccggaaa cgcatcgcga acctcccgtt gtcgatcatg accgaacggt aatacggctc
     2401 ctggtgacgg cgtggaaatc caacctgttc gagttacgcc cgactgtcca ctgtggtctt
     2461 cacccgaacg tcgaaagccc gtccagcaac ctgtcgacgt cgtcgatgct ggtgtacggt
     2521 gccagcccga cccggagcgc cggatcctcc agcttcaagg ccgcgaagac ttcgtgggcg
     2581 tagaaggatc ccgccggcgc gacgacgttc ctttcggcga gatgccgttg cgcctcgcgc
     2641 tcccggccac cgaggcccat cagcacggtc ggggtccggt ccgccgcctt gcagtggacg
     2701 gtgacggcgt cgcccagccc ctcctccagc ctggcgcgca acgtgctttc gtgctcgtgc
     2761 aacgagttca tcgaattcgc gagccgttct cgccgtgatc cgcccgctcc ggggtccagc
     2821 gcggcgagga agtccaccgc cgccgtggca cccgcgagca tttcgtaggg cagcgtgccg
     2881 aattcgaacc gctcgggcac gctgtcgggc gacggcacga gcttgtccgg ctcgacggtt
     2941 tcgagcaggg cgggcgacgc gccgagcacg ccgcagtgcg ggcccaggaa cttgtacggc
     3001 gagcagacga agaaatccgc tccgagcgcg ggcacgtcca ccagttcgtg ggcggcgtag
     3061 tgcactccgt ccacgaacac cagcgccccg gcgtcgtggg cgagatcggc gatccggcgg
     3121 atctgcggct tggtgccgag gacgttcgag gctgccgtga ccgcgaccag cctcgtccgt
     3181 tcggtgagga cgagggaatc gaggtcgagt tccgtggttt ccgggtcgat gtcgagccaa
     3241 cggacggtca ttccggcgcg ctcagcggcc tggacccacg gccggacgtt ggcgtcgtga
     3301 tcgagacggc tgacgacgat ctcgtcgccc tcgcgccagc ttttggccag gtgccgggaa
     3361 aagtcgtacg tcagctgggt ggcgctgcgg ccgtggacga cgccttcggc aggcacaccg
     3421 aggaagtccg cgtaggcgtc gcggaagccc gagacggcgt tctccgcgtt gagttcggac
     3481 ggactgacct tgccccggtt cgacaacgga ccggtcagcg tcccggcgat ggcgtcggcg
     3541 acgggccggg gtgtctgggt acccgcgggt ccgtcgaaaa aggcggttcc gtcggcgagg
     3601 gaggggaagt ggagccggag ggcggcgaca tcgatggcca tgtccccgac tctgacatcc
     3661 ggcgaggcac gcgtaaacgc ttcgtggccg gaacttcctc cggccacgaa gcgtctcgga
     3721 ctcagtacag cgtcaaccgg tacgcgccgg actgcgcggt cccggcgaac agataccggc
     3781 cgtccgcgct gaccgccagg gagagcaccc tggaatcggg cagcgcgccg ggcacgggcg
     3841 accaggtgcg gccgaagtcc gtgctgcgca gcacgccgcc gccggtcgcg ttgctcgcga
     3901 accacacccg gaagtcgaac ggatgcggca ggatccggct gatctcacgg gggtcctcgc
     3961 cgtcgaagac ccggcggaac gtcttgccgc cgtcttcact cagatggatg cccgcgccgc
     4021 cgatgagcac gcggccgcca ccccatcggc tgatcgagat cgcactgacc ggctggctgg
     4081 tcacgtgggt ccaggtcttg ccgccgtcgt ccgaccggga caggccgtcg gagtccccgc
     4141 cccagacccg gtccgggttc cacggatcac cggcgaacgc gatgaagccg ttgtcggtcg
     4201 cgagcttctc ccaggtcttc ccggcatcgt tgctgcggta gagcacgtag ccgctgggag
     4261 cgaaggccga gacgagcacc cggttcgggt cggccgggtg ggcgaagatc gcccggggga
     4321 ggccttcctt cgccttcgcc gcgaattccc aggtccgccc gccgtcgcca ctgcggagca
     4381 cgtcgagcga gaaaccgttc cgggtgacct gccagacgac gtccggtcgg ctcggcgaga
     4441 cggacagacg cgcgtcctcg tgcagccggt cggccgggtg cgactgccag acccggtccg
     4501 ccgcggccac cttgccgcgc gggagcggcg tgttgtagat ctcctgcaca cccgccgcga
     4561 cgacgctctc gcgcagcagg ttcccggtgg tcacgaggtc gcggatggat tcgccaggga
     4621 caccgatctg ctgatagccc cgcttgccct cgtccgcgta cacgcctcga tagagcgagg
     4681 agatcagcgt cgtggcgggt ttgcccggtc cggcggggag gtcgatcatg tcgctgacgc
     4741 cttcgcccgc cgcgggcacc ggtttgcggg accaggtgcg gccgaagtcc gcgctgacgt
     4801 ctatgtcgtt atacgtcgac acgtacagcc gtccaccgag gaaacgcggt tcgcgcaggg
     4861 tctgctcgcc gggatcgcgg cgcagtaccg tccaggtctt gccgccgtcg gtggagccgt
     4921 gcagttcggg gccgaccgtg accacgaagc gcttgccgtc cgaggcgacc tggttgatct
     4981 cgccgttggc ccggtagacg agttcggcct gcggctcctt gccgctgacc cctcggacca
     5041 cccagagggc gtactcgggg aggaccgtcg tgaggtaggc gtcgtcgccg accatcgtga
     5101 gcttgagcgc gccgaccggc gaggcgttgc cctcacgcgg ccaggtcctc ggcacgtcgt
     5161 tccagtgctc gccaccatcg gtgctgacgc tcagcgaatc catgttctgc accacgacca
     5221 cccggccggt cgggtccgtg gccatgccga acgcaccgtc ggggtaccac tcgcgcaggg
     5281 tttcccaggt ctggccgcgg tcggtggtcc gcaccagcat gccgcgccat tcgccgagga
     5341 agcccgccgg tttgttgccc accgcgagca tccggtccgg gttcgccgga tcgacgaaga
     5401 atccctggat ggaggtgtcc tgcggcagtc cgcggcgcac actccaggaa gcgccgcgat
     5461 cgccggagag ccacagagcg ggcgggctcg gctgcatcat cgcgaggccg gccggcgaaa
     5521 cggcgagcat cccgccgacg ctgttcgggc cgaccggttc ccagccgccg cgcggcttcc
     5581 cggtcgcgtt gacgtccgtg ggcggtgcct ggggttcggc ggtggccacc gacgtcgccc
     5641 cggtggtgcc gagaaccgtc agcagcccga gaacgaacat gcgtttggtg atcgatctca
     5701 gtttcatgcg ggagatcttg gcgcaagatc cggaaaagag atagaggatt cgtcggatct
     5761 ttgcctggcg ataacccctt cccatcttcg ataagccttg tcaagacttg acttaccgaa
     5821 aactcatcgg atgactatgg cgatcagcgc ggcggcgagc agggcgaggt acgcgatcgc
     5881 gtgcgcacgg tccgggatcc ggccgaccac ccggcgcgtc acggcgatgg tcgggagcga
     5941 tccgcacagc agcgcgcccg cggccacgag gtcgacgtag ccgacgtgag cgccgcccga
     6001 ggacgtgccc gtcgccgcga aggcgtagac ggctgtgccg atcaccgcca cgggcaggct
     6061 cagcgggttc gcgagcgcgg tcgcgtcggc catcggcagt cccttgcgcc gcatgagcgg
     6121 cacggtgagg acgctgcccc cgacgccgag aaagctcgcc acggcaccga tcccggtccc
     6181 gcccgcgatg gtggtgaccc cgccgagagc acgcggtccg tcgtcctccc gtctgctcac
     6241 gaaacctttc cgggcgacgc tgtcggcgat ggtcagcgcg aggtaggcga cgaagagcca
     6301 gcgcaggaca ccctcgtcgg ccacggtggc ggtgaaggag ccgagcacgg cgcccaaacc
     6361 gatgaaggcg atgagcggcc acagatagtc gcggcggagc cggcccgtcc gcagctgggc
     6421 gagggtcgcg ctcccggcgt tgaccaccat cacggcggtc gacgtggcca ccgccacgtg
     6481 catcgcgtcc tgtgcgtgct ccggatccgc gagcgcgaag gcgtagacga cgggcacggt
     6541 gatgaacccg ccgccgaatc cgaaaaggac ggtggtgacg ccgctcaggc aaccgaaccc
     6601 gaggagcacc gagatctcga tcagcactcc ctcgacggta ggccccggcg gcacggcggg
     6661 cattcgaaag gtcgccagtt tctttcgcgg atcggacacc cggcgtagcc tcggtgaggt
     6721 gcgtgacatc cccatcgacg aggtcgacca tctcgaccgc gcggtggtgg cgatccgcac
     6781 cgattaccca ccggggcacc ggatcctccc gcatcggcac cggcgggcgc agttcctcta
     6841 cagcgcgacc gggtcgatgc gggtcgaaac ggccgacggc acgtggacca tcccgacccg
     6901 gcgcgcggta ctcgtcccgc cggagaccgt ccatcaggtg ttcacgacga ccgtgagcac
     6961 ccggagcctg tacatcgagc cgaaggcggt gccgtggttc ccgcgccgct gccaggtcgt
     7021 cgaagtgtcc gcgctgctcc gggaactcct gaacgaggcc gtcggcgtgc cggagctgta
     7081 caccgctcgc ggacgagacg ccgcggtcat cggcctgacc ctgcacgaga tccgccggtc
     7141 cgcgccggtc cggctcgacc tcccgctgcc gaagcacgaa cgtctgcgag cccagtgtga
     7201 gtcctttttg gacgctccgg acatccacga tcccgcgagc gagtgggcga accggctgca
     7261 cgtgagcgaa cggacgctga accggctctt caccgcggag accgggatgg gtttcgcccg
     7321 ctggcggcaa cgggcctgcg tcctgcattc cctgtcactg ctgtcggacg gcctgcccat
     7381 cgccgcgatc gccgcctcgc tcggctacga gagccccgcc gcgttctcga cgatgttcac
     7441 tcggcttctc ggcacttcac cgagggacta tcgcgccgcg tccgcgctct gaacccggtg
     7501 tctcgcccag gcgaacaaag gagttcgtcg catcagtaag aacgtactcg tcaccggcac
     7561 cgcacgaggg aaaccgccgc cgccttgggt tccctggcgg aatcttcgcc ggattccgac
     7621 tacgcctgac ggcgctcatc cacgctgtgc tcgtgccgcc ccgacgcagt acacaccgaa
     7681 ggccgcgacc ccgaccgcca ccacgatgag gagcacggtg ccgaacggct gggcggccaa
     7741 ggtccgcagg gcggcgtcga gcccgccgga acgggacggg tcatgcgtca acgccgcgta
     7801 cccgaccagt acggagacca ctccgaacac gacacccctt gccacgtaac cgatcctgcc
     7861 cagacgctcc acccatcgcc gcgtccccga cgggagcttc gcgaggtcga ggtcctgatc
     7921 gaaggtccgg cgtatcccct tcaccgccga gcccaccgcg acgccgaaca cgatgacggc
     7981 caccacggtc accaggaacg ggccggcggg caatccgagc agccaggcgg tgaactcctg
     8041 ctgcttctgg tcgccgctgc cctgttcccc cgcccccaag gcgaccttgg ccgcgtacac
     8101 gccgagcgaa atccccacca ggcagcgcac tccggacgtc acccgcttga cggtgcgagt
     8161 gcgctgcttg tcgatccacg tgtagccgac ggcggccagc aacccctgcc acaggccgta
     8221 ggccaccagt cccaccgcca atacccacaa cagcaccccg cccgccgggg tcgaaccgac
     8281 ctcggtgatc gcgccgcgtc cgtcggcctc ctgtccgcca ccgccgacgg cgacacgcgc
     8341 cgccaggtac ccgatgagca gatacaccag cccgtagcag cccatgccga tccgtccgag
     8401 cacctggacg gccttgttgt ggcgcacctg tctcgccttg gtcgtggaca tccggtccac
     8461 ctcctcagag tctccatcga gtgtcgccgc cgagggtgaa gaccgccgcg tgactggtcc
     8521 gtccggccca gcgcgaagga ggcttaagcg gacagccagt cgtcggtgtc acgatgcctg
     8581 ccgagaccga cggcgtcgaa ctcgtcgaag tggtcgccct tgagcacgcc cagccgtcga
     8641 agcgcctggg agatcgggct gccgtcggcc gggtcgggtt cgtcttcgtc gacctgcagc
     8701 gggccgagaa cggtctcgcc gccttcccac acctgagcga actgcgtccc ggcgccaccg
     8761 aagtactcgg cctcgacgta cgccacggcc ccgtgctcgg agcactcggc gagcggcccg
     8821 gtgtcgaatc gcgtctcggc caccggcatc agcgacaggt cctgcccgag cggcacgagc
     8881 ctcgcacctt cgagcgaatc gagcactcgg cgccgtgcgg actcggtgac gatgacggct
     8941 cgcaggcaat acatgcccgc atcctgccag ttcgccgtcc cgcgaagatt tttccgccga
     9001 cgatgtctat ccgcgccgcc cgcgttcgta gccagggtga gagacgaact cacccgaagg
     9061 agcatcatga ccgcgaccta cacgttcgac gtcttttcca gcctcgacgg ctacggcgcc
     9121 cacaccggcg attggggcgg ttactggggc aagcaaggcc ccgaattcct cgaacaccgt
     9181 ctggccctgt actccgagaa gcagcggatg gtcttcggcg cctccacgtt ccggacgaac
     9241 atggagatgc tcaacgcgga gatcccggac gtcgaggcgc tggatccgtg ggtctcccgg
     9301 ctgaagcacc tgccggcgac ggtcgtctcg acgaccctgc gggagccgct cgcctggccg
     9361 gacgcgaccg tcgtgagcgg ggacgcggtc gacgtcgtcg cccggctcaa ggaggagtcc
     9421 gaagtgccgc tgcgctcgca cggcagcctg tcgatgaacc gggcgctgat ggccgccggc
     9481 ctggtcgatc gcgtgcaggt gacggttttc ccggtgatca ccgggaaaac cggggcggac
     9541 gcgatcttcc gcggtgcggc cgacttcgac ctcgaactgc tcgagagccg gacgttcgac
     9601 gggcgtgtcc aggagctcgt ctaccggccg gctccgcact gaccatccac aaaggacggt
     9661 cgcgtcgatc ccgcctacgc ggtgatcgac gcggccggtg ccccgagcca gggcgccagc
     9721 agggcttcga ggtcggcgtc cgacagcgcg tacggtccgc cgtggaactc gtgccaccgc
     9781 gaagcgtccc gcgccgccgt gtactccacc tcgaacgccc gcatcaggac gtacatgaag
     9841 gtcaccgagc tgaaccgctc accgagcaac gtcctggcct cgcgcgcgac accggtcgcg
     9901 ccatggccga gtacgtccgc gagcttcagc tcctccgcag ccgggtccaa caggctgggg
     9961 gcatacatca cgacaaaatc tccatcactg aaaggaaaac tcagttctcg gcggcgagct
    10021 gaccgcacgc cgccgcgatc tcctgaccac gcgtgtcacg caccgtgcac gccacaccgc
    10081 ccgcgttcac cagccggacg aactcccgct ccaccggctt cggcgaggcg tcccacttgc
    10141 ttcccggcgt cgggttcagc gggatcacgt tcacgtgcac caactggccc aggtgctgac
    10201 gaagccgctt cgccagcagt tcagcacgcc aaggctggtc gttgacgtcc cggatcagcg
    10261 cgtactcgat cgacacgcgg cggccggaag tgtccgcgta gtaccgggcc gcggacagga
    10321 cctcgtccac cgaccagcgc tcgttcaccg gcaccagtgt gtcccgcagt tcgtcgtccg
    10381 gcgtgtgcag cgaaaccgcc aggcgcacct gcatcttctc gtccgccagc ttccggatcg
    10441 ccggcgcgag acccaccgtc gacacggtca ccgaacgctg accgatcccg aggccctccg
    10501 gcgagggatc ggtgatccgc cggaccgccg ccaccacccg cttgtagttc gcgagcggct
    10561 cgcccatgcc catgaagacg atgttcgaca ggcggccggg accgccgggc atctgtccgt
    10621 cgcgcatcac ggcggcggcg gagcggacct ggtcgacgat ctccgcggtc gacaggttcc
    10681 ggtcgaggcc gccctgcccg gtcgcgcaga aggggcacgc catgccgcac cccgcctggc
    10741 tcgagatgca cagggtcgcg cggtccgggt agcgcatcag cacgctctcc agcagcgtcc
    10801 cgtcgtgcgc gcgccacaag gtcttgcggg tggtcccgtc gtcgcaggcg agcgccttga
    10861 tctcggtgag cagtgtcggc atcagatcgc cgacgagctt ctcccgcgac gcggccggga
    10921 tgtcggtcat ctcctccggg ttcaccgtga gccgcgagaa gtagtggttc gaaagctgtt
    10981 tcgcgcggaa cggcttctca cccagctcgg cgacggccgc ggcccgctcg gcggcggtga
    11041 gatcggcgag gtggcgcggc gggaggccgc gcttgggcgc gtcgaagacg agagggaggg
    11101 cagtcatagc tcattcagtg tcccacgtcc acctgcgacg cacctcggcc gccctggatc
    11161 gctgttcccc aggtcacgtg agccgtgccc ggaccgaccc atgcgtcgtt cacgccggat
    11221 cgtgcggatc gcacgtcagg agacgtccgg aggtcacgtc cggcgccaga cttgttcatg
    11281 tcacgccacg gagcgtgacg accccgagtg aactacagga ggaaccatga tctcgacctt
    11341 cgagcgcccc gccgccgtcg tcgtccacaa ccgcgccgtg gtccacaacc gcgcggtcgt
    11401 ccacaaccgc gccgtcgtgc acaaccgcgc ggtcgtgcac aaccgttccg ccgccaagta
    11461 accggccgac cagccgcccg cgccgccgcg atcccggcca cggggatcgc ggcggcgagg
    11521 cgggagtcca ggaaacgatg gggttgccat ggggtccgaa gaggtcagac cgcggctcga
    11581 cgggatcgag atcaccgatc tcgaaccaga gctctgcttt ctcgtcacgc ccaacggggg
    11641 acagttctac atcgccgcgc ccaccgggga attccgcgcc tgggcgagcc gttgcgacgg
    11701 cacccggacc cgctccgagc tgctggacgg catggatccg gactacgcgg aaatgatgga
    11761 catcctcgaa gcggacggct gcctccgtcc cgaccggggc accgaggccg acgacgtcac
    11821 caccaccgcg atcgttctca ccggctcgcc cgtgctcatc gagccgctgg cggagatcct
    11881 cgaggcggtc gggtacgcga gcgtcgaaac ggtcccttac ttccatgacc tgtccgaaat
    11941 ggacctgaac aacacggtcg tggtctccgc cttcgatcac cccgcctaca ccgaattgat
    12001 cgcgctggac gcgttgtgcg ccggaagcgg ggtgcgctgg cttccgttgc gccgcgaacg
    12061 cggccgggtg atcgccggac ccgcgatcgc gcccggcggc atcgatttcg ccgacgtcgt
    12121 cgcgcggcgc cgctccgccg cgcaagaccc gcgtgtcgtc gaggcgttcc tttccgcccc
    12181 ctccgactcc accccgcttc ggcccggtga cgcccgctgg gcgctgacca ccctcgccgt
    12241 ccatctcgga cgctggctct ccggcgggcg aaccgccatg accaccggcg agatcgaact
    12301 caacccggcg gacctgaccg agatccgccg cccgatcctc cccgtccccg accgggcccg
    12361 gaccgttccc accgtgaccg atcccgagct gctggtggac gatcagaccg ggatcgtgac
    12421 cggcgtcggc gaaatcccgc ccactccggg aatgcccgcc cggctgcggg tctgcgcggt
    12481 cgacgtcgcg gacatgcgcc gggtgacgaa ctggcccaac gaccgccagg ccttcggcac
    12541 gtcgtggtac gacttcgacc tcgcacggca gtcggccatc ggcgaagcgg tcgagcggta
    12601 ctgcggaagc tggctcgctc cggagcgcga agtgtgcttc ggcagctaca accagttcct
    12661 ccgctacggc gtccccgcgg tcgaccctcg acggctgaac ctctattcgg cttcgcagta
    12721 ccggtcgccg ggtttcccgt tcgcgccgct cacccgggac acggagtgtt cgtgggtgga
    12781 aggcttctcc cacaccaccg gcgaacccgt gtgggttccg gctttcctgt tctcgaacga
    12841 acgccggccc ggggaagcgc atttcgccga ccctctgatc gccggcctcg cgagcgggac
    12901 caccgaggag cacgccgtca cgtccggcct cgaagaggtt ctcgagcgcg acacgaccat
    12961 gctctggtgg gccaacacac cacgactcgg ccgtctctcg atcccggacg agatccggtc
    13021 gctcatcgcc gacgccaccg acgactacga ggtcgcgctc atccacctgg acaacgagtt
    13081 cgacgtcccg gtgatcgccg cggcggtgtt cgaccgggtg aagcgctggc tgtcgatcgg
    13141 cttcgcggcc cggccggacg cgctggaggc cgccaagaag gcgctcgccg aaggcttcac
    13201 gctccagcac acctgccacg cactcgacga cgaacgcgag ttgtccggta tgcgccggga
    13261 cctgccgcat ctgggcaacc tcaaaccgca ccgggccgat cggcgctacc tggactcgta
    13321 tcgccacgat ttcgccgacg tcgcggatct cctttgccag caacagatct acctcgaccc
    13381 acgggccgcg aagcgagtga agccctgggt catggacctg ccgagccgcg actgggccga
    13441 ccttcccgcc ctcggcgagc ggcggctcaa ggcctaccaa gcccgcgtcg aaggccgggg
    13501 gttcgaggtg atcagcgtcg acctgacgac ctgtgacgtc gcggccgccg gattccacgc
    13561 cgcgcatacg ctcgtgccgg gcctcgtttc gaacttcccc gccggctcgc cgttgtgggg
    13621 gaacggaagg atcgccgacg cggccgtgga actcggctgg cgggacgaac ctctcgccga
    13681 gcacgaactc aacgtcttcc cgcttcccca cgcgtgatgg ccaccgcgga cctgctcggt
    13741 ctccccagca cccgcgggcg gttcccgctc atcgcggcgc aaagcgtcga cgcgctcggg
    13801 accggtctgt tcctcccgtt cgccgtcgtg tacttccacg cggccaaggg cctgtcgctg
    13861 acggccgtcg gagcggcgct gtcgatcgcg gcgctgatcg cgttgccgtc ggggccgctc
    13921 gcgggacggc tgatcgaccg gttcggacca ggccggatgg tgatcaccgc caacctgatc
    13981 cgggcggtga ccttcaccgg ctacgtcttc gccgacgagg catggcatct ggtcgtcctg
    14041 gccgcggtga ccttctgggg cgagggcatg ttctggccgt cgaccggcgc gctggtggcg
    14101 caggtggccg acgacggcca gcgcgcccgc tggtatgcga tggaacgcgc gctgcgcaac
    14161 gtcggcatcg ggctcggcgg gctcctcggc gcggcgatgg tcgcgtgggg cggcaccgcc
    14221 ggctacacgg cgatcgtgct ggtgaacgcc gccagtttcg tcgtcgccgc ggttctggtc
    14281 gcgtcgtggc gcgccccggc gggcaccccg cgcgagaccg aaccagaggc cgctcccgcc
    14341 ggcggctacc ggaaggtgtt cgccgaccgg atctttcgcg gcgttctcgt gaccgtcttc
    14401 gtcttcgcgt tgtgcgacct ggcgttgacc gtcctgctga gcgcctacgt cctcgacggc
    14461 ctgaaactgc cggcttggca gcccggggtc ctgttcacgg tcaacacggt gctgatcgtg
    14521 ctcgcgcaga ccgtggtgtc acgccgggtc gagcggcgaa gcatgccacg cacactccgg
    14581 ctctcggccg cggtctgggc gatctcgttc gccctgttcg cgctggtacc caccggagag
    14641 tccacggcgg cgttcctcgt gctcgccctc gcgatgatcg tcttcacctg cgccgaactg
    14701 ctccaggcgc cgaccagcag cgcgctgacc gtcgcgatcg ccccggcgcg gctgcgcggc
    14761 cgctatctcg gcctcgaaga actcgtgtgg agcgcggcgc gggtgatcgc cccggcgatg
    14821 ttcacctggt tgctgtcgca cggtccggct ctgccgtggc tggtgctgat cggcttctgt
    14881 ggcgtggcga tcgtggtgct gggcagactg aaccgtgcgc tctgaactgg acgacgtcta
    14941 ctgccgcgtc tatcgcgaac cgccttacct cgaaggcgag gacgacgtcg cccggttcgg
    15001 cgtgctgttc gccgaacacg ccgcgctccc cgggttcgcc atgacgacgg tgcgcgaagc
    15061 cggaacgatc ggcggcttcg cctacggggt ccggcgagaa gccggctggt ggcctggccg
    15121 tgcgacggct ccggctccct cgtggctcga cggcgaggag ctgttctacg tatacgaact
    15181 ggcgctcgtc cccgagctcc gtggccgcgg actgggccgc gctctactcg acgacctgct
    15241 gaaagagcga ccggaacggt tcgccgtact cgcctcacgc gtcgaggcgc cggcgcggcg
    15301 gctctatcac cgttggggat ggcggaaggt cggcgcgttc gactccggcg gcatcgacct
    15361 gctcgcactc gccctctcct gagacccaga tcaccgaaga cgggttgccg tacgactgtt
    15421 tccgatatat cgtgaacgag tcggaacatt acgaagagag gattcacatc atgcgacgac
    15481 gacctttccc tccagaacac ggccgacccg ccttcgggcc ctgggctcgc ggcggcttcg
    15541 gcgacttccc cccgggcccg ggtgggccgg gccaccggca ccggcacggc cgtcgcggcg
    15601 gccccggtgg acggcgcggc aaacgcggtg acgtccgcgc cgcgatcctg gcgctgcttt
    15661 ccgagcagcc gaggcacggc tacgagatca tccgtgagat cggcgaacgc agcggcggct
    15721 tctggaagcc gagccccggc tcggtctacc cgaccctgca gatgctggcc gacgaaggcc
    15781 tggtgatcag caaggacgag aacggcaaga agctgttcga gctcaccgaa tccggccgcg
    15841 ccgcggccga gcagcaggac gccgtcccgc cgtgggagca gatcgcccac gacgtcgacc
    15901 cggtcgaggt gaacctgcgc aaggcgggcg cgaccctggc cgcggcggtc gcgcaggtca
    15961 tgcacgccgg cagcgaaagc cagcaggccc gcaccgtcga cgtcctcaac gaggcacgcc
    16021 ggacgatcta cggcatcctc ggcgaggccg aggacaccgc cccggacgag gacacggagt
    16081 gatccggcac gacgaggccg gtgggcttgg cgcgcgtatg cacgcgatag cccaccggca
    16141 gcgtcacctg cttctcccct gcacctgacg aaacctcgtt gagccgccgg acctccgcga
    16201 tcgccttcgc cgcgaccgga gcgctgaact cgatcttcag caccgcttcc atcgcggcgg
    16261 cgtcttcgaa cagccaccgc gtcatcacct tgcggcagtc gaatccctga cgcgcgaaga
    16321 acttctcgac cccgggcggg tcgtagtgcg gcagatccag ccgcatccag cggccgtagg
    16381 gctcactcgt cacgtcgaga tccacgatca tcatcagccc acccgggcgc agcacccgct
    16441 ccgcttcgcg aagaccgggt tcgcaaccgg ggccgaagaa gtacgcggtg cgggcgtgga
    16501 cgacgtcgaa agccgcgtcc ggcaagggaa gccgctgcgc acgcccctgc cgcacctcga
    16561 cgttcgccag ccgctccacg cggttccgcg cgtcacggac gagcggctca tggggttcga
    16621 cgccgaccac cgaccgcgcc gtcgcggcga accgcggcag gtggaaaccg tcaccacagc
    16681 cgatgtcgag gacgtccgcc ccggaccaat cgcgggcccc ggtgagcacg cgccagatct
    16741 cgtcgtcgac gtcctgcgcg cggttttcga cctcgtaggc cttttggtaa taccagatgt
    16801 tcggactcgg cagcacctcc tcgccgccgc ggcgggagga ggagagagct cggggaaacc
    16861 agcgcacgga agctccaacg aagggacacc gggccgggtt ccggagtatc cgggccgaaa
    16921 tctttgacgg aaacaatgcg gtcagcgact agactttact cccaccggta agggagaacc
    16981 gcatgtcgct tggctcggcc gcccacactt ccgtcatacc ttcgggaatc ccgtgctgga
    17041 tcgagctcgc gtgcagagac gaagcggccg cacaagcctt ctacagcggg cttttcgact
    17101 gggagttcac cgtccagcgt gatccggcga cgccgaccgg ccggtattcg atcgcgacgc
    17161 tgaacggcgt cccgaccggt ggtctgtacc gcgcgggcgc ggacggaccg tccggctgga
    17221 gcgtccacat ctcggtgtcc caggcggccg ccgccgccga atgggtggac agtctcggtg
    17281 gccgggtcac actcggaccg atggcgatcc cccatcgcgg cagcatcgtg cacgccatcg
    17341 acgcgtgcgg cgcgcacgtc gtcttctggg agcctcccgc cacctgggag ttcgcgaccg
    17401 gggtgccgaa caccttcagc ggcgcggatc tcaacaccca cgacggcgcg gcggcggatc
    17461 acttctactg ccgcctcttc gactacacca gccaccagat cggcgacggc gcgtcgctcg
    17521 actacgccga atggctcatc gagcacgaac cggtgctgta ccggtacgtc atgggctcgg
    17581 aataccggcc ggacactccc ccgcactgga tggtctacct cgccctcgac ccggctcgcg
    17641 gcgcggacgc cgcggccgga caggcgttga tgctcggcgg tgccgtcgtg gtccagccct
    17701 acgacacccc gtacggccgg atggcgatcc tcgccgaccc ggacggttcg gtcttcgccg
    17761 tgatcgacca ctcccgggcc gtcgagggct ggggtaccgc cgaagtcgac gatccctacg
    17821 acgactgagc cgggcagagg ctagacgggg acgaacgccg agagcagcaa ccaggagacg
    17881 acggccgaag gaagcaagga gtcgagccgg tccatcaagc cgccgtgtcc cggcagcatg
    17941 ttccccatgt ccttgacgcc gaggtcgcgt ttgatcagcg actcgacgag atcgcccagc
    18001 gtcgccgtgc agacgatcgc cgcgccgaac agcacaccct gccaggcgtg gccgtcgagc
    18061 aggaggctca gggtcagcgc gccggcgacg acaccggcca cgagggaacc ggcgaaacct
    18121 tcccaggtct tcttcgggct gatcgtgggc gccatcgggt gtttgccgcc cagcacaccg
    18181 gcgatgtagc caccggtgtc cgaagcgacg acgccgatca tgaacgccag cacccggccc
    18241 acgccgtcct ccggcgggac gagcatggcg gcgaaggcac cgaaaagcgg gatgtacgcg
    18301 gcggcgaaga ccgacgcgct gatgtcgcgc agatacccgt ccgcgccgcc gggcaaccgc
    18361 cacagcaggc agacgagcac cgtcagcacg aacgccgtca gcgcgccttc gcggccatac
    18421 ggccaggcca gccagatcat cgcctgaccg ccgacgagca ccgggaccag cgcgatccgg
    18481 atgcccgccg cgcgcttcaa tgccccggcc agctcgatcg tgccgaccgc gatggcgatc
    18541 gcgatgatgc cgatgaacag aaagcgcacg gtgagcaggg acgtgacgat cgccgcgccc
    18601 agcagcagcc ccaccccgat cgcggcgggc aggttacggc cggcgcggga aaccttttgc
    18661 gccggttccg gcttctccgc cggaaccggt tccgggttct ccacccgatc ctcgcgttcc
    18721 tcgctcacct ggctcatcag acctcgagta gctcggcttc cttgtgtttc accagctcgt
    18781 ccaccttgtg ggtgtaggtg tcggtgaggt tctggagttc cttctcggcg tggacgacct
    18841 cgtcctcgcc cgcctcgccg tccttcttga tccggtcgag ttcttccttg gccttgcggc
    18901 ggacgctgcg gatcgagacg cgggcgtcct cacccttgga cttggcgacc ttcaccatct
    18961 ccttgcggcg ctcttcggtg agctgcggga tgacgatgcg gatcacgttg ccgtcattgc
    19021 tcgggttgac gccgaggtcc gactcgcgga tcgccttctc gatggcgttg agcgaggtct
    19081 ggtcgtaagg cttgatcaac gccatccggg cttcggggat gttgacgccc gcaagctggt
    19141 tcagcggggt cggcgcgccg tagtaatcga cgacaacgcg cgagaacatc ccggggtggg
    19201 cccggccggt gcgtaccgac gacaggtcct ccttggcgac ggacaccgct ttttccatct
    19261 tctcctcggc gtcgaggagg gtctcgtcga tcacggcaac tcccgttgtt gtgtatgcgt
    19321 accgattacg gagatcagag caggactacg cgggcacccc gtcggcgggg gtgtcgacca
    19381 gggtgccgat cctttcaccg ctgaccgcac gggcgatgtt cccctcggtg aggagattga
    19441 acacgatgat cggcatgttg ttgtccatgc acaggctgaa cgcggtggcg tcggcgacct
    19501 tgaggtcccg ttccagcacc tcgcggtggc tgatctcgtg gaacatctcg gcggtcgggt
    19561 cgctcttcgg gtccgcggtg tagacgccgt cgacggcctt cgccatcaag acggcctcgc
    19621 agccgagttc gagcgcgcgc tgcgcggcgg cggtgtccgt cgagaagtac ggcatgccga
    19681 ccccggcgcc gaagatgacg acgcggccct tctccaggtg acgctcggcg cggcgcggga
    19741 tgtacggctc ggcgacctgc cccatggtga tggcggtctg cacccgggtg ggcaggccct
    19801 ccttctccag gaagtcctgc aacgccaggc agttcatgac ggtgccgagc atcgccatgt
    19861 agtccgcgcg gtcgcggtcc ataccgcgct gcgacagttc cgcgccgcgg aagtagttgc
    19921 caccgccgat cacgacggcg atctgcacgc ccgtccgcgc gacgtcggcg atctgctggg
    19981 cgaccgagtg caccacatcg ggatcgaccc cgatggaacc gccgccgaac atctcgccgc
    20041 ccagtttcag cagcacccgc cggtatccgc cttcgacccg gacacccatg tcgccctccc
    20101 taatgctctg aaacccgact gtgccccgtc cccgatggac ggagacgggg cacagtggtg
    20161 gttcttgtgt tccgcgcctg gatcaggcct ggccgacctc gaaccgggcg aaccggctca
    20221 cggccacgcc ggcctcgtcg agcagggcct tgacggtctt cttgttgtcc ttgaccgacg
    20281 gctgctcgag caggacgttg tccttgtagt aggcgttgac cttgccctcg atgatcttgg
    20341 gcatggcctg ctccggcttg ccctcttcgc gggcggtcgc ctcggcgacg cgacgctcgt
    20401 tctcgacgat ctcggccggg acctcttcgc gggtgaggta cttcgccttg agcgcggcga
    20461 cctgcatggc agcgccacga gcggcctcgg cggcggcttc gccctcaccg gtgtactcga
    20521 tgagcacgcc gacggcgggc gggaggtccg caccgcgacg gtgcaggtac gtggtggtgg
    20581 tgccctcgta ggcggcgaca cggcgcagct cgagcttctc accgatacgg gcggccagct
    20641 cctggacctg ctcctcgacg gtcttgccgt cgagcgaggc ggccttcagc ttctcgacgt
    20701 cgctggtctt ctcggccttc gcgacctcga cgatcttcgc ggcgagggcc tggaagtcct
    20761 cgttcttcgc gacgaagtcg gtctcggagt cgagctcgat cagcacgccg ccgtcaccgg
    20821 cgacgaggcc ctcggcggtg gcgcgctcgg cgcgcttgcc gacgtccttg gcgcccttga
    20881 tgcgcaggaa ctcgacggcc ttgtcgaagt cgccgtcgtt ctcctccagc gccttcttgc
    20941 agttcatcat gccggagccg gtcagctccc ggagacgctt cacgtctgcg gcggtgtagt
    21001 tcgccatcgt gggtgtgtcc gtcctttttc aggtacgaga aagtcttttg gggaattcac
    21061 tcgtggggcc gcccggaggc ggccccacga gcgggtggat caggaggagg cggtggcctg
    21121 ctcggccggg gcctcggtcg gcgcgtcggt cgcggcggcg gcttccttgg cgtccgcggc
    21181 ggcggtctcg gagccggcga gcagctcctt ctcccactcg gccagcggct cgtccgtggc
    21241 gacgcccgcc tcgggcttgg cgtcggcgga ggaaccgttg cggctggagc gggccatcag
    21301 accggcggcg gcggcctcgg ccacgacctt ggtcagcagc gcggccgaac ggatcgcgtc
    21361 gtcgttaccc gggatcgggt agtcgacctc gtccgggtcg cagttggtgt ccaggatcgc
    21421 gacgaccggg atgttcagct tgcgagcctc gccgacggcg atgtgctcct tcttcgtgtc
    21481 gacgatccac acgatgctcg gcaccttggc catgtcgcgg ataccgccga gggtcttctc
    21541 gagcttgtcc ttctcacggg tgagcgtgag gatttcgcgc ttggtcaggc cggcgaaacc
    21601 accggtctgc tcctgcgact cgagctcctt caggcggagg agacgcttgt gcaccgtctg
    21661 gaagttggtc agcatgccgc cgagccagcg ctggttcacg tagggcatgc ccacgcgcga
    21721 ggcctcggag gcgatggctt cctgagcctg cttcttcgtg ccgacgaaca tgatggtgcc
    21781 gccgtgcgcg acggtttcct tgatgaactc gtacgcacgg tcgatgtacg tcagcgtctg
    21841 ctgcaggtcg atgatgtaga tgccgttgcg ctcggtgaag atgtagcgct tcatcttcgg
    21901 gttccaccga cgggtctggt gcccgaagtg cacgccgctg tcgagcagct gcttcatggt
    21961 gacgacggcc attgccggaa tcaacctctt ctgtgtcgtg cgcgcccggc tccgccggaa
    22021 cgcgcttgct cggttcgtcg ctctcggccg ggtggccgat cgccctggtg ccgatgctcg
    22081 ggcccggacc ctgtggcgaa gtgacctcag ggaccgccgg gccgtgtgcc cccgcctgtc
    22141 ctgaccctcc gtgaggagat cggccatcgg gagcgcgcac gtgcacgcga agtcagtccg
    22201 ctgccgcgga ccgcgcaaaa gagtctactc cctgtcgcca ccgggtaccg caccggcagc
    22261 ccctgatgag aggggttgtc cacaaccgcc tcggttatcc acagattccc ccggcgcgcc
    22321 ccgcacgcca cgccggtccc ccagcctgga acacatgacc atgacgacct gttcccgccc
    22381 tgtcaccagg cactccttcg ccctcgaccg cgccggcggg aggcaccgcc gccccgggcg
    22441 tcctcggcgg cttccgcgcc tcgcgatcct cgcgaccctg ctcgcgatct tcgcgtcggc
    22501 ggcgatgccg ggaacggcca gaggcgcccc ctccccgcaa gggcgactct cgtggccgct
    22561 ctcgccggta ccgagcgtca ccaggtactt cgagccgccc tcgactccgt acgggcccgg
    22621 ccatcggggc atcgacctcg cctcggcacc gggcacgaac gtgctcgcgg ccgccgaagg
    22681 agtggtgatg ttcgccgggc aggtggcggg ccgcggcgtg gtgtcgatcg accacgacgg
    22741 agggctgcgc accacctacc aaccactcgc cctgacggtc accgcgggtg atcaggtcta
    22801 ccgggggcag gtgctcggga cgctcgcggc gggccatccc ggctgcccgg agccggcgtg
    22861 cctgcatttc ggcgtccggc ggggcgagga gtacgtcgat ccgctcgcgt tgatcggcga
    22921 gccgtcggag atccggctca aaccatggga aggagattga gtgaccgtta cggaacgggc
    22981 tcggggcagc cgggccgcct ccgtcgccgc ggcgtctcgg gtgcgggagt gcgatggccg
    23041 tcctccgcgg tgccgccacg tgctccttct ccgcacaatg cggtgattcg cgtgtcctgg
    23101 cggcggacac acgtgattgg acggcgaaca cgcgtgattg gggggcgaac acgcgtgatt
    23161 ggaggcgggg ctcgccgtgg cgcgtggggg gcttaggcct gctcgaccag tttggcgcgc
    23221 agccgcatga cggcgcgggt gtgcagctgg ctgacccgtg actcggtgac gccgaggacc
    23281 ttgccgatct cggcgagcgt caggctctcg aagtagtaga gaccgaccac gatccggtcg
    23341 cgttcggtga gctgcgcgat cgcctgcgcc agctggcggc ggttgtcctg gtcgaccagg
    23401 acggccaccg ggtcgacggc gccgtcgtcg ggcagggtgt cgaccagcga gccgctgtcc
    23461 ttgcccgcgg cgacgaggtc ttccagtgcg atgacgctgg tcagctgcat ctgcccgtag
    23521 aactcgcgca gatcgtcgac gctgatttcg agctcggccg cgagttcggc gtcggtcggt
    23581 gtgcggttga gccgggcgcc gaggcgttcc agggcgcgct cggcctcgcg ggccttgctg
    23641 cggaccgccc tcgggaccca gtcctgggag cggagatcgt cgaggatcgc gccgcggatg
    23701 cgctgcatgg cgtaggt
//
