LOCUS       NZ_LIWC01000003        23493 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Amycolatopsis sp. CB00013 scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_LIWC01000003
VERSION     NZ_LIWC01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Amycolatopsis sp. CB00013
  ORGANISM  Amycolatopsis sp. CB00013
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 1488769)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1488769)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905755.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:05:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,488
            CDSs (total)                      :: 8,430
            Genes (coding)                    :: 8,383
            CDSs (with protein)               :: 8,383
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 17 of 47
            Pseudo Genes (incomplete)         :: 38 of 47
            Pseudo Genes (internal stop)      :: 1 of 47
            Pseudo Genes (multiple problems)  :: 9 of 47
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 718203
            Orig. end                         :: 741696
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIWC01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23493
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23493
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23493
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13493](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13493)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(69..84)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.97"
                     /tool="antismash"
     misc_feature    complement(573..587)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(804..818)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(1023..1037)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            1054..1890
                     /locus_tag="AMK34_RS22915"
                     /old_locus_tag="AMK34_22650"
     CDS             1054..1890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332678.1"
                     /locus_tag="AMK34_RS22915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22650"
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="WP_073846742.1"
                     /transl_table=11
                     /translation="MTQTGERRRPAEPGRRPRSERVKRTPRAERTQRLKQRRGRRSADD
                     RRRSARPTRHKELRRRWVALLSVLTAVALVYLLWFSSMLGVQQVDVVGASSVPADQIRA
                     AAAVPDQKPMLRLDTDEIRDKVAQMPGIATVDVSRSWPSTLEITVTERTAIAFFDSGPG
                     GDGVHLVDGGGVVFKTVKERPAGLPELKLPLVSADDPVTRAVTGVLGVIPQQLLKQVTT
                     ATAKTPGSVEFALADGKTVRWGTSADTERKAKVLAALLTREGKVFDVSAPDLPTVS"
     gene            complement(2139..2888)
                     /locus_tag="AMK34_RS22920"
                     /old_locus_tag="AMK34_22655"
     CDS             complement(2139..2888)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332679.1"
                     /locus_tag="AMK34_RS22920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22655"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_038516423.1"
                     /transl_table=11
                     /translation="MDFERSLDLLWRDRGEARQPTRGRKPKLTLDQVIATAVALADRAG
                     EATVSMSQIAKELGAGTMTLYTYVPGKTELLDLMVDSVLAERNLPGPGDPRPDGWREQV
                     RLYAERTLAVFRAHPWLRSTSMVRPVLGPGLMAGQEYVIAAVSDIGLEPRKAAAAANSI
                     EIYVQANATLFAETAQVEQETGESTDAWWGQRSVFWEKYFDVTRHPAMTRIWESGGYDA
                     DTCEAADETFAFGLERMLDGIEALVTR"
     misc_feature    2923..2939
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            2984..3817
                     /locus_tag="AMK34_RS22925"
                     /old_locus_tag="AMK34_22660"
     CDS             2984..3817
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637674.1"
                     /locus_tag="AMK34_RS22925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22660"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_073846743.1"
                     /transl_table=11
                     /translation="MTILVTGATGSVGRLLVDELVEAGAPVRALTVNPAKAALPEQVEV
                     AKGYLGKPETLPEALEGIETVYLAPLAAKVDDFVKLAKEAGVRRVVALSGSNADDPADN
                     SSGVDYAIIEKAVREAEFDWTFLRPGAFMNNTLGWAETIKAERMVREAYPESRMTPIDL
                     ADIAAVAAHVILTEGHVGKKHTLSGPTAISQREQVAAISAALGEEVVFQELTREEANKQ
                     WAAAGVPAEIAEWLLDGFAYFTENPDKPTGVVQELTGRPGVTYAEWAVANVEAFR"
     gene            complement(3924..4688)
                     /locus_tag="AMK34_RS22930"
                     /old_locus_tag="AMK34_22665"
     CDS             complement(3924..4688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029318.1"
                     /locus_tag="AMK34_RS22930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22665"
                     /product="hypothetical protein"
                     /protein_id="WP_016332681.1"
                     /transl_table=11
                     /translation="MSFFTDGPRSRPLFPVPEQELFGYNGRPWVETPHEYIVPAILPWS
                     MPLGRAERTIVALRGIEVWPESVSFQLSVYSRDLLLDEPGEGLIDHRRVPDYNALLVGV
                     LFPDGRRASSETISVPSATKPDQPVLRAQGLGGSAFHVDHEIFLWPLPPDGPLEFIVQW
                     LDRDIEESRTSLDGTAIRDAAKEAGEIWPGLPARKSHGLPVRRVGAQAMITPAWPRESQ
                     APPPLPQPSSPPPASDQPRGAPLPTRLPRRAR"
     gene            complement(4812..6869)
                     /locus_tag="AMK34_RS22935"
                     /old_locus_tag="AMK34_22670"
     CDS             complement(4812..6869)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332682.1"
                     /locus_tag="AMK34_RS22935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22670"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_073846744.1"
                     /sec_met_domain="Pkinase (E-value: 7.6e-47, bitscore:
                     156.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTDPTLVGTLLEGRYRVDKLLARGGMSSVYRGVDTRLDRQVAI
                     KIMDPRFADDRSFVERFEREARSAARLHHPHVVAVHDQGFDTPGGEESGRAFLVMELVD
                     GGTLRELLAERGPLDVALALSITEPVLSALAAAHAAGLVHRDVKPENVLIGRGGTALSG
                     GVVKVGDFGLVRAVASAGTTSSSVILGTVAYVSPEQVATGATTSRGDVYSAGILLYEML
                     TGRPPYTGDTALSVAYRHVNDDVPRPSELRPGIPPQLDELILRATRRDPEQRPADAAAF
                     LAELNHLRTVLGVPAVPVPVPLPADADRETDAERTTPGIPAIPAVAPAAAATTVLPPVA
                     EATLPVTGPRGTQALHREPQIPAAQPPRTPPPRPKPAADDEQPGSRKRLYLMIAAAVLV
                     LGGLIGAFAFILNDSGPTSSSVPKLTGMNQAAAGDALRSAKLTPAYTEEYSDTAAQHTV
                     IRSDPAEGTSLAPGATVNVVLSKGRPIVPDIQAGTSQQDAETAIKAAQLTPVQGEQEYS
                     DVAKNKVVRVDPGPGSQLNIGGQVTIILSKGPEPLPPVPDVTGQSKDAAFQILQQAGFQ
                     PFQAGEEFSDQFAAGQVIRTDPKGGGKASNRRIGVFVSNAVEVPNVTFKRMEEAIQILK
                     QAGLEPDRQGRGNGNGHGGGNGGFDFVLEQDPQPGTKVPKGTKVKIKGFG"
     misc_feature    complement(6888..6901)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    6928..6942
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            7056..7424
                     /locus_tag="AMK34_RS42325"
                     /old_locus_tag="AMK34_22675"
     CDS             7056..7424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="AMK34_RS42325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22675"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_038516415.1"
                     /transl_table=11
                     /translation="MSGIPVADDVLDADVAVLPLPEVATALGVSANKVRQMLRDGHLIA
                     VRRKGELYVPVAFLVKDGVVKGLAGTITVLADSGFSRTEMLRWLFAEDETLPGTTPVNA
                     LRTSHGTEVKRRAQAMAF"
     gene            complement(7393..8571)
                     /locus_tag="AMK34_RS22940"
                     /old_locus_tag="AMK34_22680"
     CDS             complement(7393..8571)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332684.1"
                     /locus_tag="AMK34_RS22940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22680"
                     /product="MFS transporter"
                     /protein_id="WP_083649968.1"
                     /transl_table=11
                     /translation="MRSRYRLAVYLTGATVARTGDELSGPALLLLGLSVDGSAATGSAL
                     LAGLTISAAAGGPLLGALLDRSPRPGRLLAWALLAYAGGLGAVLALVELPAAIVVAIAA
                     GLLNPALAGGWTAQLPQVRGGTPLERASTLDAMTFTAASLAGPGLAGLVAAYAGAPAAV
                     ALAITLVAAAFPAAWSLPATEAKPTRPIRRQLADGFAVLFRNRALLRATATSTVSFVGI
                     GIAVVCYPLLGAQRLGNPGFGALLLTVLAAASLVANAVLARKPPPPDRTVFASTVLLGS
                     SFLLAAAGHDVVLLLVAAVLAGFAEGPQLSALFAIRHREAPAAVRAQVFTTAASVKITG
                     LAVGAAVAGPLSALSVTAALGAAAGFQLLAAATYVLVGTSGRTRTPSPARAA"
     gene            8594..9154
                     /locus_tag="AMK34_RS22945"
                     /old_locus_tag="AMK34_22685"
     CDS             8594..9154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332685.1"
                     /locus_tag="AMK34_RS22945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22685"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_073846745.1"
                     /transl_table=11
                     /translation="MTSAQRDFLPGRSARAAAQRAVDLMVVLLAPDPSASAVRSVLEAH
                     GETSVELTPPDVASLREAAVELREVFAARDAAGAAGVLNRLLARYAHPPRLTDHADGFG
                     WHLHVDADDDGPWGAWLVTSSALALAVLLSDRQAPPGGLCAASGCGKPFAHLGGGSPRR
                     YCSTRCATRERVAAHRRDRSRTP"
     gene            complement(9216..10004)
                     /locus_tag="AMK34_RS22950"
                     /old_locus_tag="AMK34_22690"
     CDS             complement(9216..10004)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332686.1"
                     /locus_tag="AMK34_RS22950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22690"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_038516409.1"
                     /transl_table=11
                     /translation="MTSASNRKIRIGVQLQPQHAEYKAIRRAASEAEDLGVDIVFNWDH
                     FYPLYGEPEGLHYECWTMLGAWAESTSRVEIGALVTCNSYRNPELLADMARTVDHISDG
                     RLILGIGSGWFEKDYDEYGYEFGTAGGRLDDLAEALPRIESRFGKLNPAPTRKIPVLIG
                     GGGEKKTLRLVAKHADIWHGFGDPEVVERKVKILDQHCADVGRDPKEIERSVAVDGEPE
                     ELGPKLLDLGVSLFTVATGGPDYNLDKLRSWIEWRDKQQS"
     gene            complement(10001..10930)
                     /locus_tag="AMK34_RS22955"
                     /old_locus_tag="AMK34_22695"
     CDS             complement(10001..10930)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332687.1"
                     /locus_tag="AMK34_RS22955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22695"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_073846746.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.2e-111,
                     bitscore: 366.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.9e-61,
                     bitscore: 203.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELDAAGITEPALRAAYTECRRINAHYGRTFFLATRLLPPRTRP
                     FAHALYGFARMADEVVDNPAPGTDPAVALDEVATLVARVFDGDTPADPVLTALADTVRR
                     HDLDRDLFDAFLRSMAMDLKITEYATYADLREYIHGSAEVIGLQMLPIFGTVVPVEEAV
                     PGAAALGEAFQLTNFLRDVGEDLDRGRLYLPTEELAAFGVDRELLEFSRARGLPDRRVR
                     RALAVAVARNRAVYRRAEAGIPLLREESRDCVRTALVLYEGILDEIVALGYDVLNTRAV
                     VPHRRRLGVALPRLLASTWSNSRLRLRS"
     gene            complement(10927..12402)
                     /gene="crtI"
                     /locus_tag="AMK34_RS22960"
                     /old_locus_tag="AMK34_22700"
     CDS             complement(10927..12402)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637666.1"
                     /locus_tag="AMK34_RS22960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22700"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_073846747.1"
                     /sec_met_domain="DAO (E-value: 4.8e-18, bitscore: 62.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGPSDHVVVIGGGLAGLSATLHLLGAGRRVTLLEQDKTPGG
                     RAGQADFGGNTVDTGASVLTMPELLDEAFSAVGESLADNLTLTRLDPAYRARFADGSTI
                     AVHTEAAAMEAEIREAAGPAEAEGYRRLRRWLTELYAVQKDHFIGANFDSPFDLVRPEL
                     AKLAALGGFGRLGPKIGGFLRDDRVRRLFSFQALYAGLDPARAIGAYGVISYMDTVGGV
                     YYPSGGMGEIARAMANAAERAGAELRFGTEAAWLERVSSRVRAVRTRTGERIPCDTVVL
                     ATELGTAYRLLGARPRRPLPLRYSPSAVVLHGHAPKTWPDLGHHTIFFGHAWEKTFSEI
                     IREGKLMSDPSLLVTRPTATEPALAPGGDQVISVLAPAPNLVRGKIDWGRVGPAYRAEL
                     LRTLEKRGLTGFSDDFSVDEMITPAGWAERGLTAGTPFSLAHTFAQTGPFRPGNLMRAV
                     DNVVLAGCGTTPGVGIPPVVISGRLAAGRVTGR"
     gene            complement(12402..13493)
                     /locus_tag="AMK34_RS22965"
                     /old_locus_tag="AMK34_22705"
     CDS             complement(12402..13493)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332689.1"
                     /locus_tag="AMK34_RS22965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22705"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_073846748.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-47, bitscore:
                     158.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTSAYDADLPAHVERALAGFLERAGAEIRRTEPTVGAGIDALAG
                     FVLGGGKRLRPTFAWWGWRGAGGDPSGPDVEGVLQAVASLELIQACALIHDDLIDSSDS
                     RRGSPTVHIAGAKLHADSGWLGSPSTFGLATAVLVGDLALAWADDMFGEAPLPPAALAA
                     ARPAWRAMRTEVLAGQYLDVRTQATGDASPEAALHICKLKTAAYTVQRPLHLGAALGGA
                     DDALIATLREFGDEVGVAFQLRDDLLGVFGDPSVTGKPAGDDLREGKRTLLVALGLQRA
                     AEQGKDAAAKVISDAIGDAHLSEDAVETVREALQDVGAVDAVERRIDELTDSAMAALDR
                     AHLAEPAPAALTGLVVKATQRTY"
     gene            complement(13616..14164)
                     /locus_tag="AMK34_RS22970"
                     /old_locus_tag="AMK34_22710"
     CDS             complement(13616..14164)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332690.1"
                     /locus_tag="AMK34_RS22970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22710"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_073846749.1"
                     /transl_table=11
                     /translation="MDGHWDGYDSIGGSVPLDLVNTVSWRHDPARREDRLSAPERLSEW
                     VVLVGAGTGRLEISQAVLEAVKGFRETLYRVLVSDSPDATPLRKPLLAAYRHAELTPSL
                     PLRWQVPLVDDTALPHFLALAAEDLLRSGELERIRECEGPGCGWIFTDHTRNRSRRWCS
                     SSDCGNRARAKRHYDKTRV"
     gene            14212..14880
                     /locus_tag="AMK34_RS22975"
                     /old_locus_tag="AMK34_22715"
     CDS             14212..14880
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029308.1"
                     /locus_tag="AMK34_RS22975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22715"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_038516394.1"
                     /transl_table=11
                     /translation="MTTLRRNYLAGARVGLGLGVATFVLGVTFGAYSQTLGWGIAAPIV
                     ASIVVFSGSAQFAMATALAGGGNLAVAVGAAALINARFLPMGAAVAADLRGGRLRRAWE
                     GQAVVDGSWVAAHLGEGRFDREKLIGCTLVQLPAWVLGTVLGVLAAPPPDVVSRFGLDV
                     VFPGFFLVLLIDELRRSRQAVLTAALAACLAGILVLFVPVGLALIGASAAALVGLGVRR
                     "
     gene            14877..15182
                     /locus_tag="AMK34_RS22980"
                     /old_locus_tag="AMK34_22720"
     CDS             14877..15182
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637662.1"
                     /locus_tag="AMK34_RS22980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22720"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_073846750.1"
                     /transl_table=11
                     /translation="MTLWLTIVLVALVSIGFKAAGPVLLGDRTLPPRLAGVIALLAPAL
                     LAGLVLTDVAGPAWSGLDWTLCAGLAAIAVTYVLRVPVLAAILCGVVVTAVLRFLV"
     gene            complement(15179..15856)
                     /gene="merB"
                     /locus_tag="AMK34_RS22985"
                     /old_locus_tag="AMK34_22725"
     CDS             complement(15179..15856)
                     /EC_number="4.99.1.2"
                     /GO_function="GO:0018836 - alkylmercury lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0046413 - organomercury catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="merB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332693.1"
                     /locus_tag="AMK34_RS22985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22725"
                     /product="organomercurial lyase"
                     /protein_id="WP_073846751.1"
                     /transl_table=11
                     /translation="MSAETDTSWDEDVRVAVYRAFAEHGRPPTAPELADAAHGSLAVAK
                     QALHRLAERRHLVLDECEHVVLAHPFAAIPLGFSVMGERTLWWGGCAWDAFAIPHLVKG
                     EPEVLVSTRCRGCGEPQALMVNDRTPPKGGLVAHFLVPVARMWDDVVHTCANQRLFCGE
                     SCVDEWLAETGQDKGYVMDLATLWRLAAGWYDGRLDHGYTRRDPAAAAAYFEQAGLSGP
                     FWH"
     gene            15994..16878
                     /locus_tag="AMK34_RS22990"
                     /old_locus_tag="AMK34_22730"
     CDS             15994..16878
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332694.1"
                     /locus_tag="AMK34_RS22990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22730"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_037343226.1"
                     /transl_table=11
                     /translation="MTSVVERLQGDGPVFSIEFFPPRDAADEAVLWKSIRELEPLDPAY
                     MSITYGAGGSSRDGTIRSIARVATETTLVPMAHLTAVNHSVAELRNVIGWYAAVGVRNI
                     LALRGDPPGDVYGDWVPHPDGLNYAEELVELVRSLGDFCVGVSAFPYGHPRSANLEADT
                     EYLVRKLRAGADFAIAQLFFEPEDFLRLRDRVAATGCEALVIPGIMPLTTPRTLHTSIK
                     LSGAPAPRRLLDRLEPLADDPKAFRAAGIDAVTELGERLIAEGVPDLHFYTFNRSKATR
                     EVVSRLGLVPARA"
     gene            16921..18606
                     /locus_tag="AMK34_RS22995"
                     /old_locus_tag="AMK34_22735"
     CDS             16921..18606
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075033.1"
                     /locus_tag="AMK34_RS22995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22735"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_073846752.1"
                     /transl_table=11
                     /translation="MASTARSVHEICDRYVDEYAAADPVAATTFGISGYDDQLTDYSPA
                     GHAARAAIAARALADIAAAEPVDDGERAAKAVFSERIALNLEIHEAGLDIAALNVIESP
                     VQELRMVFDFMPTETAQDWATIAARMARVPEALDGLRTSLLASADAGRVAALRQVGKVA
                     EQAETWAGLKDETGFFETLASGAKDVDEKLRAELGQAAHAAQEAYAEFAGFLRAELAPL
                     APVKDAVGAEVYQLWSRVFTGATLDLDEAYAWGWAEFTRLETEMREVAGRIKPGATLAE
                     AAAALDADPKYTVRGRAEFQAWMQNLSDNALKSLRGKHFDISDRVMALECKIAPPGGTV
                     GAYYTGPSEDFSRPGRMWWSLPQGRDEFTTWREVSTVYHEGAPGHHLQIATAVDQSESL
                     NKYQRLLAFTSGHAEGWALYSERLMEDLGFLADDGELFGMLSEQLFRAARVIVDIGMHL
                     ELEIPAGPGFHEGERWTPELGLEFMLTRTVTDPAHVHDEIDRYLGWPGQAPSYKLGERL
                     WLTAREEARARQGDAFDIKQFHTRALALGGMGLDTLREMLAALD"
     misc_feature    complement(18649..18661)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.58"
                     /tool="antismash"
     misc_feature    complement(18707..18720)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            18910..19791
                     /locus_tag="AMK34_RS23000"
                     /old_locus_tag="AMK34_22740"
     CDS             18910..19791
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637657.1"
                     /locus_tag="AMK34_RS23000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22740"
                     /product="DMT family transporter"
                     /protein_id="WP_073846753.1"
                     /transl_table=11
                     /translation="MSVAVPTRARSSAALVLAGVLWGSGGLAGSLLASRAGLHPLSVAA
                     YRLLIGGVIATGYLWLTGGLRGLPRTPQARRRLLAVGGLFALFQTSYFASVSLSSVSVA
                     TMTTIGSAPVLLAVATVVKTRRLPGAWTAVSLAGSLAGLALLQWTPGQEADVAGVLFAL
                     LAAAGFAALTLVTATRVEGLDPLPTTAFGCLIGGAALTPAALWFGMAVPFQADVLALVV
                     YFGVVPTALAYAAYFRGLESAHPVLAALSALLEPLTAALLSMAVLGERLGAVGWCGAVV
                     LIAALAVAYTKP"
     gene            complement(19788..20351)
                     /locus_tag="AMK34_RS23005"
                     /old_locus_tag="AMK34_22745"
     CDS             complement(19788..20351)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332697.1"
                     /locus_tag="AMK34_RS23005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22745"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_016332697.1"
                     /transl_table=11
                     /translation="MTAMSSECTRYVQLSADEFRARLPEALTIYVNAMRYPEGTAEQRA
                     PMWLTHALREGWRCMAALDADGVLLGLAYGYKGRGGQWWHEQVRHGLTRREGQAAAEHW
                     MSDYFELTEIHVSPESQGKRIGEDLLRRLLDGVPSAHVLLSTPEGTSRAWNLYRRVGFV
                     DVLRDYHFAGDPRPFAILGRTLPL"
     gene            complement(20348..20869)
                     /locus_tag="AMK34_RS23010"
                     /old_locus_tag="AMK34_22750"
     CDS             complement(20348..20869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156538.1"
                     /locus_tag="AMK34_RS23010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22750"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_073846754.1"
                     /transl_table=11
                     /translation="MSTIDHPSVAKVAAALAEAGQQAAADGIRILPAEVRTAAQAAEAL
                     GVEVGAIANSLVFRSRTGDTESALLALTSGAHRADTGLLASLTGADEIGKADADFVRAH
                     TGQPIGGVAPVGHPKALTTLVDTALRAHEVVWAAAGHPKSVYPTTFDGLVALTGGTPAD
                     VAGDRQDGRP"
     misc_feature    complement(20483..20485)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20975..20990)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 28.4"
                     /tool="antismash"
     misc_feature    20976..20989
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.19"
                     /tool="antismash"
     misc_feature    complement(20976..20989)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            21091..21573
                     /locus_tag="AMK34_RS23015"
                     /old_locus_tag="AMK34_22755"
     CDS             21091..21573
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156540.1"
                     /locus_tag="AMK34_RS23015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22755"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_007029300.1"
                     /transl_table=11
                     /translation="MSVSVVSPDEAERPGGTAQPALPMSLRPPAPPAAVSLYAQARRGL
                     AEAERENDPAERFIGAYLAALRGAAAVLEARGRPHRGRARPASGWVLLDSVAPELKEWA
                     AFFAANSATRAAAQAGITGKVTVELADELTRAATVFLELVRRVVHGLPMGDSAHVA"
     gene            21598..22362
                     /locus_tag="AMK34_RS23020"
                     /old_locus_tag="AMK34_22760"
     CDS             21598..22362
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637653.1"
                     /locus_tag="AMK34_RS23020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22760"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_038516374.1"
                     /transl_table=11
                     /translation="MAGQAMIDQGRFLEVIGAETELMAQVAHTASADAPVPTCPGWTLG
                     EVLRHVGSVYRVTRRWITDGRRPEHWQRKPGPGQTLDEYFREGRDELVAELSAHDPDEL
                     APTWWPADRSYGFWRRRMAHETTIHRIDAESAAGRDVSEIPEDVAVDGIDEALVLWFGQ
                     RLPLLGLSGTKTGSVGVRTAGHTWIARAGPTETVAWRCSADEAQRADDLITGKPDKIYR
                     WLWGRAGPTAVTVSGDQDMAGQLWALLRLATR"
     gene            22518..23201
                     /locus_tag="AMK34_RS23025"
                     /old_locus_tag="AMK34_22765"
     CDS             22518..23201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332701.1"
                     /locus_tag="AMK34_RS23025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_22765"
                     /product="VOC family protein"
                     /protein_id="WP_073846755.1"
                     /transl_table=11
                     /translation="MVAHLVNLVFDSALPRDLAGFWEGLFSWDAPFEPAFRSETRPKGR
                     KNRLHLDLASRSPGHQAELVDRALSLGARHIDIGQGPPEEKRVPWVVLADPEGNEFCVL
                     EPREQYEGTGAIAAVVVDALDPERLARFWAAALGWEIGVREETIVGLRPPDGRGPWVEF
                     LATKEDKLERNRLRFEVAPGPGGSRAAEVRRLLGLGALGRGTARQGAVSLVDPEGNEFS
                     VLTPR"
ORIGIN
        1 gacgcacggc aagacgtcga cgacgtcgat gctgaccgtc gcgctgcagc agtgccgtct
       61 cgacccgtcg ttcgccatcg gcggcgacct caacgagtcg ggcgcgaacg cgcatcacgg
      121 cgagggcggg gtcttcgtcg ccgaggccga cgagagcgac ggatcgttcc tggcctactc
      181 gccgtcggtc gccgtggtga ccaacgtcga gccggaccac ctggaccacc acggcacggc
      241 cgaggcgtac gtctcggtgt tcgccgactt cctcggccgg atcgtgccgg gcgggctgct
      301 catcgtctgc ggtgacgacg agggtgccga gaagctgggc gcgctggccg cggagcgggg
      361 catccgcgtc cgccgctacg ggcgttcggt caccggcgcc gacgacgcga aggtgctcga
      421 ctacgccccc gcgccggacg gcggcgtcgt ccggatctcg ttgcggggcg aggagatcgt
      481 actccgggtc gcggtgccgg gtgagcacat ggcgctgaac gcgatcgccg cgctgctggc
      541 cgggatcgag ctcggcgcgc cggtcgaagg actggccgaa gggctcgccg cgttcggcgg
      601 cgtgcggcgg cggttcgagt tcaagggccg cgcgggcgac gtccgcgtgt acgacgacta
      661 cgcgcaccac ccgaccgagg tcgacgcgca gctgcgcgcg gtgcggacgg ccgcgggcca
      721 gggccgggtc gtcgtggtct tccagccgca tctgtactcg cgcacgaagg cgttctcgaa
      781 ggagttcgcg gccgcgttgt cgctggccga cgaggtcgtc gtgctggacg tcttcggggc
      841 gcgcgagaag ccggagcccg gggtgagcgg cgcgctcatc gccgaccaga tctccggtgt
      901 tcccgtgcac taccagcccg cgttcgacgt cgcggcgaag ctcgcggcgg atctggtcga
      961 acccggcgac ctgctggtga ccatgggcgc cggcgacgtc acgcagctcg gcccggagat
     1021 cctggccgaa ctggaccggc gggcgggcta gtcatgacac agaccgggga acgccgccgc
     1081 ccggccgaac ccggtcggcg tccgcgctcc gaacgggtca agcggacccc acgggccgaa
     1141 cggactcagc ggctgaagca gcggcgcggc aggcggtcgg cggacgaccg ccgccgttcc
     1201 gcccggccga cccggcacaa ggagctgcgg cggcgctggg tcgcgctgct ttcggtgctg
     1261 accgccgtcg ccctcgtcta cctgctgtgg ttcagctcga tgctgggggt gcagcaggtc
     1321 gacgtcgtcg gggcgagctc cgtgcccgcg gaccagatcc gcgccgcggc ggcggtgccg
     1381 gaccagaagc cgatgctgcg cctggacacc gacgagatcc gcgacaaggt ggcgcagatg
     1441 cccggtatcg cgaccgtcga cgtctcccgg tcgtggccga gcaccctcga gatcaccgtg
     1501 accgaacgga ccgccatcgc gttcttcgac agcgggcccg gcggcgacgg cgtgcacctc
     1561 gtcgacggcg ggggagtggt gttcaagacc gtcaaggaac ggcccgccgg gctgcccgag
     1621 ctcaaacttc cgctggtctc ggccgacgac ccggtgaccc gcgcggtgac cggtgtcctc
     1681 ggcgtgatcc cgcagcagtt gctcaagcag gtcaccaccg cgacggcgaa gacccccggc
     1741 agcgtcgagt tcgcgctggc cgacgggaag accgtgcggt gggggacctc ggccgacacc
     1801 gaacgcaagg cgaaggtcct ggccgcgctg ctcacccgcg agggcaaggt cttcgacgtc
     1861 tcggcccccg acctgcccac cgtctcctga cgcgtttcgt cctctggatg cggtgccccc
     1921 gacgtggcac tgggtgtgtt ggtctattca aggccgggtg gcgggcgttc tcgatggggg
     1981 tcgtgagtgg taaatagcgt tagaacgcta cttaccactc acgaccccag cgggaaacac
     2041 ctgaatcggg cacgaacact cgagcctgca attcgtcctc tggatgcggt agttcgtatc
     2101 gccgactacc gcatccagag gacgaaatgc ggtagtgctc agcgggtgac gagggcttcg
     2161 atgccgtcca gcatgcgttc caggccgaac gcgaaggtct cgtcggcggc ttcgcaggtg
     2221 tccgcgtcgt agccgccgct ctcccagatc cgtgtcatcg ccggatgccg cgtcacgtcg
     2281 aagtacttct cccagaacac cgaccgctgc ccccaccagg cgtccgtcga ctccccggtc
     2341 tcctgctcga cctgcgccgt ctcggcgaaa agcgtcgcgt tcgcctgcac atagatctcg
     2401 atgctgttcg cggccgcggc cgccttgcgc ggctccagcc cgatgtccga caccgccgcg
     2461 atcacgtact cctggcccgc catcagcccg ggcccgagca ccggccgcac catggacgtc
     2521 gaacgcagcc acgggtgtgc ccggaacacc gccagcgtgc gctcggcgta gagccgcacc
     2581 tgctcgcgcc agccgtccgg ccgcggatcg ccggggccgg ggaggttccg ttcggcgagc
     2641 acggaatcga ccatgagatc gagcagttcc gtcttgccgg ggacgtaggt gtagagcgtc
     2701 atcgtgccgg cgccgagttc cttggcgatc tggctcatcg acacggtcgc ctcgcccgcc
     2761 cggtcggcga gcgcgacggc ggtggcgatc acctggtcga gggtcagttt gggttttcgt
     2821 cccctggtcg gctgccgggc ttcgccgcgg tcacgccaca acagatcgag gctgcgctcg
     2881 aagtccatcc acactccact cggccgtgaa gctggattct acattctcgt atggggtacg
     2941 gttaatctga tcccgtaggg cgtacgaaaa ggagtgggga atcgtgacga tcctggtgac
     3001 cggtgcgacc ggaagcgtcg gcaggctgct cgtcgacgaa ctggtggagg ccggggcgcc
     3061 ggtgcgggcg ctgaccgtca acccggcgaa ggcggcgctg cccgagcagg tggaggtcgc
     3121 caagggctac ctgggcaaac cggagacgct gccggaagcc ctcgaaggta tcgagaccgt
     3181 gtacctggcg ccgctcgcgg cgaaggtgga cgacttcgtg aagctggcga aggaggccgg
     3241 ggtgcgccgc gtggtggcgt tgtcgggcag caacgccgac gacccggcgg acaactcgag
     3301 cggggtggac tacgcgatca tcgagaaggc cgtccgggag gcggagttcg actggacgtt
     3361 cctgcggccg ggcgcgttca tgaacaacac cctcggctgg gcggagacga tcaaggccga
     3421 gcggatggtc cgcgaggcct accccgagtc gcggatgacg ccgatcgacc tcgcggacat
     3481 cgccgccgtc gcggcgcacg tcatcctcac cgaggggcac gtcggcaaga agcacacgct
     3541 gagcgggccg acggcgatca gccagcgcga acaggtcgcc gccatctcgg ccgcgctcgg
     3601 cgaagaggtg gtcttccagg aactcaccag ggaagaagcg aacaagcagt gggccgccgc
     3661 cggggtcccg gccgagatcg ccgagtggct gctcgacggc ttcgcgtact tcaccgagaa
     3721 ccccgacaag ccgaccggcg tcgtccagga actcaccggg cggcccggcg tcacctacgc
     3781 ggagtgggcg gtggcgaacg tcgaagcgtt ccgctgagcc gtcactcgcg tgattgaagc
     3841 cgtatctcgc gtgattggag acgttccggc ttcgatcacg cgagatccgg ccaggaacac
     3901 gcgagatacg ggttgccggc ccctcagcgg gcccggcggg ggaggcgggt cggcagtggg
     3961 gcgccccgcg gctggtccga agcggggggc ggggacgatg gctggggcag cgggggcggg
     4021 gcctgcgatt cgcgcggcca ggccggggtg atcatcgcct gggccccgac ccggcggacg
     4081 ggcagcccgt gcgacttccg ggcgggcagg ccgggccaga tctcgcccgc ctccttggcc
     4141 gcgtcgcgga tggcggtgcc gtcgagcgag gtgcgcgact cctcgatgtc gcggtcgagc
     4201 cactggacga tgaactccag cggcccgtcg ggcggcagcg gccacaggaa gatctcgtgg
     4261 tcgacgtgga acgccgaacc gcccagcccc tgcgcgcgca gcaccggctg atccggtttg
     4321 gtggccgacg gcacggagat ggtctccgaa ctggcccgcc tgccgtcggg gaacagcacc
     4381 ccgaccagca gcgcgttgta gtccgggacc cggcggtggt cgatcaggcc ttcgccgggt
     4441 tcgtcgagca ggagatcccg cgagtacacc gacagctgga aggacaccga ctccggccac
     4501 acctcgatgc cacgcagcgc cacgatggtc cgttcggcgc ggcccagcgg catcgaccag
     4561 ggcaggatcg ccgggacgat gtactcgtgc ggcgtctcca cccaggggcg gccgttgtag
     4621 ccgaacagtt cctgttccgg caccgggaac agggggcggc tgcgcggacc gtccgtgaag
     4681 aagctcatcg tggcgcggcg gaacgcgggg tgaagctgtc cgacctgccg ttcacgccgc
     4741 cgactaccac catgcgctca cggtagccga tgaccatgcc ggtactgaac ggtttcaaag
     4801 cacctttcgc gtcacccgaa gcccttgatc ttcaccttcg tgcccttcgg caccttggtg
     4861 cccggctgcg gatcctgctc caggacgaag tcgaaaccac cgtttccgcc gccgtgaccg
     4921 ttcccgtttc cgcgaccctg acggtccggc tccagacccg cctgtttcag gatctggatc
     4981 gcctcctcca tccgcttgaa ggtcacgttc ggtacttcga cggcattcga aacgaacacg
     5041 ccgatccggc ggttgctcgc cttgccgccg cccttcgggt cggtgcggat cacctgaccg
     5101 gcggcgaact ggtcggagaa ctcctcgccg gcctggaacg gctggaagcc cgcctgctgc
     5161 aggatctgga acgcggcgtc cttgctctgg cccgtgacgt ccgggaccgg cggcagcggc
     5221 tcggggccct tggacaggat gatcgtgacc tgcccgccga tgttcagctg cgaaccgggg
     5281 cccgggtcga cgcggaccac cttgttcttg gcgacgtcgc tgtactcctg ctcgccctgg
     5341 accggcgtca gctgcgcggc cttgatcgcc gtctccgcgt cctgctggct cgtcccggcc
     5401 tggatgtccg gcacgatcgg acggcccttc gacagcacga cgttgaccgt ggcgcccggc
     5461 gcgagcgacg tgccctccgc ggggtcggag cggatcaccg tgtgctgggc ggcggtgtcg
     5521 ctgtactcct cggtgtaggc cggggtcagc ttcgccgacc ggagcgcgtc accggcggcg
     5581 gcctggttca tcccggtcag cttcggcacc gacgacgacg tcgggccgga gtcgttgagg
     5641 atgaaggcga acgcgccgat caggccgccg agcaccagta ccgcggccgc gatcatcagg
     5701 tagagccgct tgcgcgaccc cggctgttcg tcgtccgcgg ccggtttggg ccgcggggga
     5761 ggcgtgcggg gcggctgcgc ggccgggatc tgcggctcgc gatgcagcgc ctgcgttccg
     5821 cgcggcccgg tgacaggaag ggtcgcctcg gcgaccgggg gcagcacggt cgtcgcggcc
     5881 gcggccggag ccaccgccgg gatggcgggg ataccggggg tggtgcgctc ggcgtcggtc
     5941 tcgcggtcgg cgtcggcggg cagcgggacg ggcaccggga ccgccgggac gccgaggacg
     6001 gtgcgcagat ggttcagctc ggcgaggaac gccgcggcgt cggcgggccg ctgctcgggg
     6061 tcgcggcgag tggcgcgcag gatcagctcg tccagctgcg gcgggatacc cggccgcagc
     6121 tcgctcgggc gcgggacgtc gtcgttgacg tgccggtacg ccaccgagag cgcggtgtcg
     6181 ccggtgtacg gcgggcgtcc ggtgagcatt tcgtagagca ggatcccggc cgagtagacg
     6241 tcgccgcgcg aggtggtcgc gccggtcgcg acctgctcgg gcgagacgta ggcgacggtg
     6301 ccgaggatga cgctcgaact cgtggtgccc gcgctcgcga ccgcgcggac cagcccgaag
     6361 tcgcccacct tgaccacgcc gcccgacagc gcggtccccc cgcggccgat gaggacgttc
     6421 tccggtttga cgtcgcgatg caccaggccg gcggcgtgcg cggcggccag cgcggagagg
     6481 accggttcgg tgatgctcag cgcgagcgcg acgtccagcg gaccgcgttc ggcgagcagt
     6541 tcgcgcaggg tgccgccgtc gacgagctcc atgaccagga acgcgcggcc ggactcctcg
     6601 ccgccggggg tgtcgaagcc ctggtcgtgc accgccacca cgtgcgggtg gtgcagccgg
     6661 gccgccgaac gggcttcccg ctcgaagcgt tcgacgaagg acctgtcgtc ggcgaaccgc
     6721 gggtccatga tcttgatggc gacctggcgg tccaggcggg tgtcgacgcc gcggtacacc
     6781 gacgacatcc caccgcgtgc gagcagcttg tccacccggt agcggccctc gagcagagtg
     6841 cccaccagcg tggggtccgt gcgtgtcacg gctatggatc gtacggaagt acccatgttc
     6901 tggtgtacgg gacctgggtc gccggggatc acgattctcg acatttcgtc gaatcggcgg
     6961 tatccgtgac catgcgggca ctgtccgtca cagctcgcgg ccgtcaccca tgcgcactaa
     7021 cggaggggga gacggaatgt ggcacagtgt cacctgtgag tggtattccc gtcgccgacg
     7081 acgttctcga tgccgatgtg gccgttctcc cgcttccgga ggtcgcgacc gccttgggcg
     7141 tttcggccaa caaggtccgc cagatgctgc gcgatggcca cctgatcgcc gtccggcgca
     7201 agggtgagtt gtacgttccg gtcgcgttcc tggtgaagga cggcgtggtc aaggggctgg
     7261 cgggcaccat caccgtgctc gcggactccg ggttcagccg gacggagatg ctgcgctggc
     7321 tcttcgccga ggacgagacc ctgcccggga ccacgccggt caacgcgctc cgcaccagcc
     7381 acggcaccga ggtcaagcgg cgcgcgcagg cgatggcgtt ctagtccgcc cggacgttcc
     7441 gaccagtaca tacgtcgcag ccgcgagaag ctggaatccc gccgcggcac ccagcgcggc
     7501 ggttacggag agtgcgctca acggtccagc gaccgcggct ccgaccgcga gtccggtgat
     7561 cttcacgctc gccgccgtcg tgaaaacctg agctcgcacc gccgcgggcg cctcgcgatg
     7621 ccggatggcg aacagcgccg aaagctgggg tccttccgcg aaaccggcga gtacggcggc
     7681 gaccagcagg agcaccacgt cgtgacctgc cgccgcgagc aggaagctcg agcccagcag
     7741 gacggtgctg gcgaacacgg tgcgatccgg cggcggtggc ttgcgggcca gtacggcgtt
     7801 cgcgaccagt gacgcggcgg ccagcacggt gagcaggagc gcgccgaacc ccggattccc
     7861 cagtcgctgg gcgccgagca gcggatagca gaccacggcg atcccgatgc cgacgaagga
     7921 cacggtggac gtcgcggtgg cccgcagcag cgcgcggttg cggaagagga ccgcgaaccc
     7981 gtcggcgagc tgacggcgga tcggtctcgt gggcttcgcc tcggtggcgg gcagcgacca
     8041 tgcggcgggg aaggcggccg cgaccagcgt gatcgcgagc gccaccgcgg ccggggcgcc
     8101 ggcgtacgcg gcgacgagcc cggcgagtcc cggtccggcg aggctcgcgg cggtgaacgt
     8161 catcgcgtcc agcgtgctcg cccgctccag cggtgtcccg ccgcggacct gcggcagctg
     8221 cgccgtccag ccgcccgcca acgcgggatt gagcagcccc gccgcgatgg ccaccacgat
     8281 cgccgcgggg agctcgacca gcgcgagcac cgcgccgagc ccgcccgcgt acgcgagcag
     8341 cgcccacgcc agcagccgtc ccggtcgcgg gctgcggtcg agcagggcgc cgagcagcgg
     8401 cccgcccgcc gccgcggaga tcgtcaggcc cgcgagcagc gcggacccgg tcgcggccga
     8461 gccgtcgacg ctgagaccca gcaggagcaa cgcaggcccg gacagctcgt cgccggtcct
     8521 ggcgaccgtc gcgccggtca ggtagacggc gagcctgtaa cggcttctca tgactgagac
     8581 gttacagtgg gatatgactt cagcgcagcg ggatttcctg cccggccggt cggcgcgggc
     8641 ggcggcacag cgcgcggtgg atctgatggt cgtgctgctg gcgccggatc cgtcggcttc
     8701 cgcggttcgt tccgtcttgg aagcgcacgg cgaaacgtcg gtcgagttga ctccgccgga
     8761 cgtcgcgtcg ttgcgcgagg cggccgtgga actgcgggag gtgttcgcgg cgcgggatgc
     8821 cgcgggggcg gccggcgtgc tcaaccggct gctggcccgc tacgcgcatc cgccgcggct
     8881 gaccgatcac gcggacgggt tcggctggca tctccacgtg gacgccgacg acgacgggcc
     8941 gtggggcgcg tggctggtga cgtcgtccgc gctggcgctg gccgtgctgc tgtcggaccg
     9001 tcaggcgccg ccgggtgggc tgtgtgccgc ttcgggctgc gggaagccgt tcgcgcactt
     9061 gggcggtggg agcccgcggc ggtactgctc gacgcggtgc gctacccggg agcgggtggc
     9121 ggctcaccgg cgcgatcggt cccggacgcc atgaaaggtc ctttccttgc aaaatttgca
     9181 aggaaaggac ctttcatggc gcgtgaagga gcgggtcagg actgctgctt gtcccgccac
     9241 tcgatccagg accgcagctt gtcgaggttg tagtcgggtc cgccggtcgc cacggtgaac
     9301 agcgagacac ccaggtccag cagcttcggg ccgagttcct cgggctcacc gtcgacggcg
     9361 accgaacgct cgatctcctt cgggtcgcgc ccgacgtcgg cgcagtgctg gtcgaggatc
     9421 ttgaccttgc gctccaccac ctccgggtcg ccgaagccgt gccagatgtc ggcgtgcttc
     9481 gcgaccaggc gcagcgtctt cttctcgccg ccaccgccga tcagcaccgg gatcttgcgg
     9541 gtcggcgccg ggttcagctt gccgaaccgg ctctcgatgc gcgggagcgc ctcggccagg
     9601 tcgtcgagcc gcccgcccgc ggtgccgaac tcgtagccgt actcgtcgta gtccttctcg
     9661 aaccagccgg agccgatgcc gaggatcagc cgtccgtcgg agatgtggtc gacggtgcgg
     9721 gccatgtcgg cgagcagttc ggggttgcgg tagctgttgc acgtcaccag cgcgccgatc
     9781 tcgacccgcg acgtcgactc cgcccaagcg cccagcatcg tccagcactc gtagtgcagc
     9841 ccttcgggct cgccgtagag cgggtagaag tggtcccagt tgaagacgat gtccacaccg
     9901 aggtcttcgg cctccgaagc cgcccgtcgg atcgccttgt actcggcgtg ctggggctga
     9961 agctggacgc cgatccggat cttcctgttc gaagcagagg tcatgatcgc agcctaagcc
    10021 tggagttgct ccacgtgctc gccagcagtc tcggcagcgc gacacccaga cggcggcggt
    10081 gggggacgac cgcgcgcgtg ttcaacacgt cgtacccgag ggccacgatc tcgtcgagga
    10141 tgccttcgta gagcacgagc gcggtccgca cgcagtcacg ggattcctcg cgcagcaacg
    10201 ggatgcccgc ttcggcgcgg cggtacacgg cccggttgcg tgccaccgcg acggcgagcg
    10261 cgcgccgcac ccgccggtcg ggcaggccgc gggcgcggga gaattcgagc agctcgcggt
    10321 cgacgccgaa cgcggccagt tcctcggtcg gcaggtacag ccgcccccgg tccaggtcct
    10381 cgccgacgtc gcgcaggaaa ttggtcagct ggaacgcctc gcccagcgcg gcggcgccgg
    10441 gtacggcttc ctcgaccggg acgacggtgc cgaagatcgg cagcatctgc aggccgatca
    10501 cctcggccga accgtggatg tactcccgga ggtcggcgta ggtcgcgtat tcggtgatct
    10561 tgaggtccat cgccatggac cgcaggaacg cgtcgaacag gtcgcggtcg aggtcgtggc
    10621 gccgcacggt gtcggcgagc gccgtcagca ccggatcggc gggcgtgtca ccgtcgaaga
    10681 cccgcgcgac cagggtggcg acctcgtcca gcgcgaccgc cggatcggtg ccgggcgcgg
    10741 gattgtcgac cacctcgtcc gccatgcgtg cgaagccgta cagcgcgtgc gcgaacggcc
    10801 gcgtccgcgg cggcagcagc cgggtcgcga ggaagaaggt gcggccgtag tgcgcgttga
    10861 tgcggcggca ttcggtgtac gcggcccgca acgccggttc ggtgatgccc gcggcgtcga
    10921 gttcgctcat cggccggtga cccttcccgc cgcgagcctg ccggagatca ccaccggcgg
    10981 gatgccgacg cccggcgtgg tcccgcagcc ggccagcacg acgttgtcca ccgcccgcat
    11041 caggttcccc ggccggaacg ggccggtctg cgcgaacgtg tgcgcgagcg agaacggcgt
    11101 gcccgcggtg agcccgcgtt ccgcccagcc cgccggggtg atcatctcgt cgacggagaa
    11161 gtcgtccgag aagccggtga ggccgcgttt ttccagcgtg cgcaggagtt ccgcgcgata
    11221 cgcgggcccg acccggcccc agtcgatctt gccgcggacg aggttcggcg ccggggccag
    11281 taccgagatc acctggtcgc cgccgggcgc gagggccggt tcggtcgccg tcggccgggt
    11341 caccagcagc gaaggatcgc tcatcagctt gccttcgcgg atgatctccg agaacgtctt
    11401 ctcccaggcg tggccgaaga aaatggtgtg gtggcccaga tccggccacg ttttcggcgc
    11461 gtgcccgtgc agcacgacgg ccgacggcga gtaccgcagc ggcagcggac gccgggggcg
    11521 ggcaccgagc agccggtacg cggtgccgag ttcggtcgcg agaaccaccg tgtcgcaagg
    11581 gatccgctca cccgtgcggg tccgtaccgc gcgcacccgc gaggaaaccc tttccagcca
    11641 agcggcttcg gtgccgaaac gcagctccgc gccggcgcgt tcggccgcgt tcgccatcgc
    11701 ccgcgcgatc tcgcccatcc cgcccgacgg gtagtagacc ccgccgacgg tgtccatgta
    11761 ggagatgacg ccgtacgcgc cgatcgcgcg cgccggatcg agccccgcgt agagcgcctg
    11821 gaaggagaac agccggcgca cccggtcgtc gcgcaggaac ccgccgatct tcgggccgag
    11881 ccgtccgaaa ccgcccagcg cggccagctt cgccagctcc ggacgcacga gatcgaacgg
    11941 cgaatcgaag ttcgcgccga tgaagtggtc cttctgcacc gcgtacagct cggtcagcca
    12001 gcggcgcagc cgccggtagc cctcggcctc ggccggaccg gcggcctcgc ggatctcggc
    12061 ctccatcgcc gccgcctcgg tgtgcacggc gatcgtgctc ccgtcggcga accgcgcgcg
    12121 atacgcgggg tcgagccgag tcagcgtgag gttgtccgcc agggattcgc cgacggcgga
    12181 gaaggcttcg tcgagcagtt ccggcatggt cagcacgctg gcgccggtgt cgacggtgtt
    12241 gccgccgaaa tccgcctgtc cggcccggcc gccgggagtc ttgtcctgct ccagcagggt
    12301 cacccggcgt ccggcgccga gcaggtgcag cgtcgccgac agcccggcga gcccgccacc
    12361 gatcaccacc acgtggtcac tcggaccggt gaccgtgcgc atcagtaggt ccgctgggtc
    12421 gccttgacga ccagcccggt cagcgcggcg ggagcgggtt cggccaggtg ggcgcggtcc
    12481 agcgcggcca tcgcggagtc ggtgagctcg tcgatacggc gttccaccgc gtcgacggcg
    12541 ccgacgtcct gcagtgcttc gcgcacggtc tcgacggcgt cttcggacag gtgtgcgtcg
    12601 ccgatggcgt cggagatgac cttcgcagcc gcgtccttgc cctgttcggc cgcccgctgg
    12661 agacccagcg cgaccagcag cgtccgcttg ccctcacgca ggtcgtcgcc cgcgggtttg
    12721 ccggtgaccg acgggtcgcc gaacacgccg agcaggtcgt cccgcagctg gaacgccacg
    12781 ccgacctcgt cgccgaactc gcgcagcgtc gcgatcaggg cgtcgtcggc gccgccgagc
    12841 gcggcaccga ggtgcagcgg gcgctggacg gtgtacgcgg ccgtcttgag cttgcagatg
    12901 tgcagcgccg cctcggggga ggcgtcgccg gtggcctggg tgcggacgtc gaggtactgc
    12961 ccggcgagca cctcggtgcg catcgcgcgc cacgccggcc gcgccgccgc gagggccgcg
    13021 ggcgggagcg gggcctcgcc gaacatgtcg tcggcccagg ccagcgcgag gtcgccgacc
    13081 aggacggcgg tcgcgagccc gaacgtgctc ggcgaaccca gccagccgct gtcggcgtgc
    13141 agtttggcgc ccgcgatgtg caccgtcggc gaaccgcggc gcgaatcgga ggagtcgatg
    13201 aggtcgtcgt ggatcagcgc gcacgcctgg atcagctcca ggctcgccac cgcctgcagg
    13261 acaccttcga cgtccggccc gctcgggtcg ccgcccgcgc cgcgccagcc ccaccaggcg
    13321 aacgtcgggc gcaggcgttt gccgccgccc agcacgaatc cggccagcgc gtcgatcccg
    13381 gccccgaccg tcggctcggt gcggcggatt tcggcaccgg cgcgctcgag gaatccggcc
    13441 agcgcccgct cgacgtgggc gggcagatcg gcgtcgtagg cggacgtgtc catgagcaca
    13501 tcctccggga aggacgtcgt cgtgacccag tcgggtgcct tcgaatgtgg cggaactcgc
    13561 cgcattccgt cctctgaatg cggtagttgc ccgcgcaagg accgcattca gaggactaaa
    13621 cgcgggtctt gtcgtagtgc cgcttcgccc gcgcccggtt cccgcagtcc gacgaactgc
    13681 accagcgccg cgaccggttg cgcgtgtggt cggtgaagat ccagccacag ccggggccct
    13741 cgcactcccg gatccgttcc agttccccgg accggagcag gtcctcggcc gccagcgcga
    13801 ggaagtgcgg caacgcggtg tcgtccacca acggcacttg ccaccgcagc ggcagggacg
    13861 gcgtgagttc ggcgtgccgg tacgccgcga gcagtggctt ccgcagcgga gtggcgtccg
    13921 gtgaatccga caccagcacg cgatacagcg tttcgcggaa gcccttcacc gcctccagga
    13981 cggcttggga gatctccagc cgtccggtgc ccgcgccgac caggacgacc cactcggaca
    14041 gccgttccgg cgccgaaagc cggtcttccc gccgggccgg atcgtgccgc caggaaacgg
    14101 tgttgaccag gtccaacggc acgctcccgc cgatgctgtc gtacccgtcc cagtggccgt
    14161 ccacgaatcc tcctaatggt caaaactagt ttagcttgtt agggtcgagg tatgacgaca
    14221 ctccggcgga actacctggc cggcgcccgt gtcgggctcg gactgggtgt cgcgaccttc
    14281 gtcctcggtg tcaccttcgg cgcgtacagc cagaccctcg gctgggggat cgccgccccc
    14341 atcgtcgcct cgatcgtggt gttctccggc tcggcccagt tcgcgatggc caccgcgctc
    14401 gcgggcggcg gcaacctcgc ggtcgcggtc ggcgcggccg ccctgatcaa cgcgcggttc
    14461 ctgccgatgg gcgccgccgt cgccgccgat ctgcgtggcg gacgcctgcg ccgcgcgtgg
    14521 gaaggccaag ccgtcgtcga cggttcatgg gtcgccgccc acctcggcga aggacgcttc
    14581 gaccgcgaga aactcatcgg ctgcacgctc gtccaactgc ccgcgtgggt gctggggacg
    14641 gtgctcgggg tgctggccgc gccgccgccg gacgtcgtct cccggttcgg gctcgacgtc
    14701 gtgttccccg gcttcttcct ggtcctgctc atcgacgaac tgcgccggtc acggcaggcg
    14761 gtgctgaccg cggcgctcgc cgcctgcctt gccgggatcc tggtgctgtt cgtcccggtc
    14821 gggctcgcgc tgatcggcgc ttcggccgcc gcgctggtcg ggctgggggt gcggcgatga
    14881 cgctctggct cacgatcgtc ctggtggcgc tggtcagcat cgggttcaag gcggcgggac
    14941 cggtcctgct cggcgaccgg acgctgccgc cgcggctcgc gggggtgatc gcgttgctcg
    15001 cgcccgcgct gctggccggg ctcgtgctta cggacgtggc cggcccggcc tggtccgggc
    15061 tcgactggac gctttgcgcc ggtctggccg cgatcgcggt gacgtacgtg ctgcgcgtgc
    15121 cggtgctcgc cgcgatcctc tgcggcgtgg tcgtcacagc ggtgctgcgg ttcctcgtct
    15181 agtgccagaa cggtccgctc agcccggcct gctcgaagta ggcggccgcc gcggccgggt
    15241 cccggcgggt gtagccgtgg tcgagcctgc cgtcgtacca gccggccgcg agccgccaca
    15301 gcgtcgccag atccatgacg taacccttgt cctgccccgt ttccgccagc cattcgtcca
    15361 cacaggactc accgcagaac aggcgctggt tggcacaggt gtgcacgacg tcgtcccaca
    15421 tccgcgccac cgggaccagg aaatgcgcga ccagaccacc cttcggcggg gtccggtcgt
    15481 tcaccatcag cgcctggggt tcgccgcagc cgcggcaacg ggtggacacc agcacctcgg
    15541 gctcgccctt gaccagatgc gggatcgcga acgcgtccca cgcgcagcca ccccaccaca
    15601 acgtgcgctc gcccatcacg gagaacccga gcgggatcgc cgcgaacgga tgcgccagca
    15661 cgacgtgctc gcattcgtcg aggacgagat gccgccgctc cgcgagccgg tgcagtgcct
    15721 gtttcgccac cgcgagcgat ccgtgggcgg cgtcggccag ttccggggcc gtcggcggcc
    15781 tcccgtgctc ggcgaacgcg cggtagaccg ccacgcggac gtcctcgtcc cagctggtgt
    15841 cggtttcggc gctcatggcg gctccctgtg ctcgtctccg agtctcccca ggtcggcccc
    15901 cgtcggcaac cgctcgtacg tggccgaagt cgcccgtcca tagcctgaga gggggctccc
    15961 agccagcgga cattccccct taacatgggc cgtatgacgt cggtggtcga gcggttgcag
    16021 ggtgatggac ccgtgttctc catcgagttc ttcccgcccc gggacgcggc cgacgaggcc
    16081 gttctatgga agtcgatccg ggaactcgag ccgctggacc cggcttacat gtcgatcacc
    16141 tacggcgcgg gcggctccag ccgggacggc acgatccgca gcatcgcccg cgtcgcgacc
    16201 gaaaccacgc tggtgccgat ggcgcacctc accgccgtga accactcggt cgcggaactg
    16261 cgcaacgtca tcggctggta cgccgccgtc ggcgtgcgga acatcctcgc gttgcggggc
    16321 gacccgccgg gcgacgtcta cggcgactgg gtcccgcatc cggacgggct gaactacgcc
    16381 gaggaactcg tcgaactggt gcgttctctc ggcgacttct gcgtcggagt ctcggccttc
    16441 ccgtacggcc accctcgctc ggccaacctc gaagccgaca ccgaatacct cgtgcgcaag
    16501 ctgcgcgcgg gcgcggattt cgcgatcgcg cagctgttct tcgaaccgga ggacttcctc
    16561 cgcctgcgtg accgggtggc ggccaccggc tgcgaagcgc tggtcatccc cggcatcatg
    16621 ccgctgacca cgccgcggac gctgcacacg tccatcaagc tgtccggcgc gcccgcgccg
    16681 cggcggctgc tggaccggct ggagccgctg gccgacgacc cgaaggcctt ccgcgccgcg
    16741 ggtatcgacg cggtgaccga gctgggcgag cggctcatcg ccgaaggcgt ccccgacctg
    16801 cacttctaca cgttcaaccg gtccaaggcc acgcgtgagg tggtcagcag gctcgggctc
    16861 gtccccgcgc gggcgtaact ccgtaccgaa gtcgcccgcg atcccggtag cgtgccggtc
    16921 atggcttcaa ccgcgcgaag tgtgcacgag atctgtgacc ggtacgtcga cgagtacgcc
    16981 gcggccgacc cggtcgccgc gacgacgttc ggaatctccg gatacgacga ccagctgacc
    17041 gactattcgc ccgccgggca cgcggccagg gccgcgatcg ccgcgcgcgc actggccgac
    17101 atcgccgcgg ccgaaccggt cgacgacggt gaacgcgcgg ccaaggccgt gttcagcgag
    17161 cggatcgcgc tgaacctcga aatccacgaa gcgggcctcg acatcgcggc gctgaacgtg
    17221 atcgaaagcc cggtgcagga actgcgcatg gtcttcgact tcatgcccac cgagaccgcg
    17281 caggactggg cgacgatcgc cgcccggatg gcgagggtgc ccgaagcgct cgacggtctc
    17341 cgtacgtcgc tgctcgcgtc cgccgacgcg ggccgggtgg cggcgttgcg gcaggtcggc
    17401 aaggtcgccg aacaggccga aacctgggcc gggctgaagg acgagaccgg tttcttcgag
    17461 accctcgcct ccggcgcgaa agacgtcgac gagaagctcc gtgccgaact cggccaggcc
    17521 gctcacgccg cccaggaggc gtacgcggag ttcgccggtt tcctccgcgc cgagctcgcc
    17581 ccgctggcgc cggtcaagga cgccgtcggc gccgaggtct accagctgtg gtcccgggtg
    17641 ttcaccggcg ccaccctcga cctggacgag gcctacgcct ggggctgggc cgagttcacc
    17701 cgcctcgaaa ccgagatgcg cgaggtcgcc ggccggatca aacccggtgc caccctcgcc
    17761 gaggcggccg ccgccctcga cgccgacccc aagtacaccg tgcgtggccg ggcggaattc
    17821 caggcctgga tgcagaacct gtccgacaac gcgttgaagt cgttgcgcgg caagcacttc
    17881 gacatctccg accgggtgat ggcgctggag tgcaagatcg ccccgcccgg cggcaccgtc
    17941 ggcgcgtact acaccggccc gagcgaggac ttctcccgcc ccggccgcat gtggtggtcg
    18001 ctgccgcagg gccgggacga gttcaccacc tggcgcgagg tcagcaccgt ctaccacgag
    18061 ggcgcgccgg gtcaccacct gcagatcgcg accgcggtcg accagtcgga gtcgctgaac
    18121 aagtaccagc ggctgctcgc gttcacctcc gggcacgccg agggctgggc gctgtactcc
    18181 gagcggctca tggaggacct cgggttcctc gccgacgacg gcgaactgtt cggcatgctg
    18241 tccgagcagc tgttccgcgc cgcgcgggtg atcgtcgaca tcggcatgca cctggaactg
    18301 gagatcccgg cgggccccgg tttccacgag ggcgaacggt ggacacccga gctgggcctg
    18361 gagttcatgc tcacccggac cgtcaccgac ccggcccacg tgcacgacga gatcgaccgc
    18421 tacctgggct ggccggggca ggcgccgtcg tacaagctcg gcgaacggct ctggctcacc
    18481 gcccgcgagg aggcccgcgc gcggcagggc gacgcgttcg acatcaagca gttccacacg
    18541 cgggcgctgg cgctcggcgg gatggggctg gacacgctgc gggagatgct ggccgctctc
    18601 gactgacccg ccactcccgc ccgccccgtg ccaggaacgg tcctttcctt gcaaatttcg
    18661 ccaggaaagg accgttcctt gcatccggag ggggcctccg cgtgccgcaa ttcacgtgcc
    18721 cccggtaccg cggccttgat acgttccctc tcgtgcaccg gatctttctc gtcaccccac
    18781 cccccgctgc ctgagcgggg tgtctccggc cgcgcggcgt tcccgccgcc cggccgatcc
    18841 gtgctgcact gaagcacccc gcgtcgtcga cgtcctttcc gacagacaca gacgcaggag
    18901 cgtttcccca tgtccgttgc cgtacccacg cgtgcccgat cgtcggccgc gctcgtcctc
    18961 gccggggtcc tctggggatc cggcggcctc gccggatccc tgctcgcctc ccgggcgggg
    19021 ctccatccgc tgagcgtcgc cgcgtaccgg ctgctcatcg gcggcgtgat cgccaccggc
    19081 tacctctggc tcaccggagg ccttcgcggc cttccccgca cgccacaggc ccgtcgccgc
    19141 ctcctggcgg tcggcgggtt gttcgcgctc ttccagacca gctacttcgc ctcggtctcg
    19201 ctgagttccg tgagcgtcgc gacgatgacc accatcggca gcgcgccggt gctgctcgcc
    19261 gtcgcgacgg tcgtcaaaac ccgccgcctg cccggagcgt ggacggcggt gtccctggcc
    19321 gggtcgctcg ccgggctcgc gctgctgcaa tggacgccag ggcaggaagc cgacgtcgcc
    19381 ggtgtcttgt tcgccctgct cgccgcggcc gggttcgccg cgctgacact cgtgaccgcg
    19441 acccgggtcg aggggctgga tcccttgccc accacggctt tcggctgcct gatcggcggc
    19501 gccgcactca ctcccgccgc gttgtggttc gggatggccg tgccgtttca ggccgacgtg
    19561 ctcgcgctcg tcgtctactt cggcgtcgtg cccacggcgc tggcgtacgc cgcgtacttc
    19621 cgcggcctcg aaagcgcgca tccggtcctg gccgcgttgt ccgcgctgct cgaaccgctg
    19681 accgccgcgc tgctgtccat ggccgtgctc ggggaacggc tcggcgccgt gggctggtgc
    19741 ggcgcggtgg tgctcatcgc cgcgctcgcg gtcgcctaca cgaaacccta gagcggcagc
    19801 gtccggccga ggatcgcgaa gggccgcgga tccccggcga agtggtagtc ccgcagcaca
    19861 tcgacgaatc cgacgcgccg gtacaggttc caggcccggc tggtgccttc cggcgtggaa
    19921 aggaggacgt gggcgctggg cacgccgtcg agcagccgtc gcaggaggtc ttcgccgatc
    19981 cgcttcccct ggctttcggg gctgacgtgg atctcggtga gctcgaagta gtcggacatc
    20041 cagtgctcgg cggcggcctg gccctcgcga cgggtcaggc cgtggcggac ctgttcgtgc
    20101 caccactggc cgccgcggcc cttgtagccg taggcgagcc cgagcaggac gccgtccgcg
    20161 tcgagcgcgg ccatgcagcg ccagccttcg cgcagcgcgt gcgtgagcca catcggcgcg
    20221 cgttgctccg ccgtgccttc ggggtagcgc atggcgttga cgtagatggt cagcgcctcg
    20281 gggagccggg cgcggaactc gtccgcggac agctggacgt agcgggtgca ttccgaggac
    20341 atcgcggtca cgggcgccca tcctgcctgt cgcccgcgac gtccgcggga gtgcccccgg
    20401 tcagcgcgac gaggccgtcg aacgtcgtgg ggtacaccga cttcggatgc cccgcggccg
    20461 cccagacgac ttcgtgggcg cgtaacgcgg tgtcgacgag ggtggtcaac gccttcgggt
    20521 gaccgaccgg ggcgacgccg ccgatcggct gcccggtgtg cgcgcggacg aaatccgcgt
    20581 ccgccttgcc gatctcgtcg gcgccggtca gtgaagcgag gaggccggtg tcggcgcggt
    20641 gcgcgccgga ggtcagggcg agcagggccg attcggtgtc gccggtgcgg ctgcggaaga
    20701 cgaggctgtt cgcgatcgcg ccgacctcga caccgagtgc ttcggcggcc tgggcggccg
    20761 tgcggacttc ggcggggagg atccggatcc cgtccgcggc ggcctgctgg cccgcctcgg
    20821 cgagcgcggc cgcgaccttg gccaccgagg gatggtcgat ggtgctcata cgcctatgag
    20881 atcacgtggc cgatgccgtg tcccgcacca catgcggcga tcaccccgct acggggttga
    20941 agaaatgagc acttcagggt tacattggag ttgttcgaac agacgttcga cattcggtga
    21001 gcgcgcaccg gtaggtgccc ggcgcggggg cgggggaagc gcctcggcgc cgggcaccgg
    21061 ccggcgctca cgtacaggag gagggtcgtc atgtccgttt cggtcgtgtc ccccgacgaa
    21121 gccgagaggc cggggggcac cgcgcagccc gccctgccca tgtcgttgcg cccgccggca
    21181 ccacccgcgg cggtctcctt gtacgcacag gcgaggcggg ggctcgccga agcagagcgg
    21241 gaaaacgatc ccgcggagcg gttcatcggc gcctatctcg ccgcgctgcg gggcgccgcg
    21301 gcggtactgg aggcccgcgg ccgtccgcac cggggccgtg cccgcccggc gagcggctgg
    21361 gtgctgctcg actccgtcgc gcccgaactg aaggaatggg cggcgttctt cgcggccaac
    21421 tcggcgacgc gggccgccgc gcaggcgggt atcaccggca aggtcaccgt cgaactggcg
    21481 gacgagctga cgcgggccgc cacggtgttc ctggaactgg tgcgacgggt ggtgcacggg
    21541 ctgccgatgg gtgattcggc acatgtcgcc tgaatcaccg gggagagggg gtgcccgatg
    21601 gccgggcagg ccatgatcga ccagggcagg ttcctggagg tgatcggcgc cgaaaccgag
    21661 ctgatggctc aagtggcgca caccgcgtcc gccgacgcgc cggtcccgac ctgccccggc
    21721 tggacactcg gcgaggtcct ccggcacgtg ggcagcgtgt accgggtcac ccgccgctgg
    21781 atcaccgacg ggcggcgtcc cgagcactgg cagcgcaaac cggggccggg gcagaccctg
    21841 gatgagtact tccgcgaggg ccgggacgag ctcgtcgccg agctgtccgc gcacgatccg
    21901 gacgaactgg caccgacctg gtggccggcg gaccgcagtt acgggttctg gcggcgccgg
    21961 atggcgcacg agacgacgat ccaccggatc gacgcggaga gcgcggccgg ccgggacgtg
    22021 tcggagatcc ccgaagacgt ggcggtcgac gggatcgacg aggcgctggt gctctggttc
    22081 gggcagcggc tgccgttgct cgggctgtcc ggcaccaaga ccggatccgt cggtgtccgc
    22141 accgcgggcc acacctggat cgccagggcc ggccccacgg agacggtcgc ctggcggtgc
    22201 tcggccgacg aagcccagcg cgcggacgat ctgatcaccg ggaagccgga caagatctac
    22261 cgctggctct ggggccgggc gggtccgacg gcggtgacgg tcagcggaga ccaggacatg
    22321 gcgggacaac tctgggccct tctgcggctc gcgacccgat gaccggtcgg tggggaagcc
    22381 aaaccggtca agagcgggtc gacggagctg aagatgtgcc tgtagagcga ccgaacacgt
    22441 gaacctactc ggccgccgtt ggtcgcgggt tcacctacga caaggaaagt gtcggtggtg
    22501 ccgtctaggt tcacggtgtg gtggcacatc tggtgaacct ggtcttcgat tcggcccttc
    22561 ccagggatct ggcgggtttc tgggaagggc tgttcagctg ggacgcgccg ttcgagccgg
    22621 cgttccggtc cgaaacgcgc cccaaagggc gcaagaaccg gctgcatctg gatctggcga
    22681 gccgttcgcc cgggcaccag gccgagctgg tggaccgtgc gctgtccctc ggcgcacgac
    22741 acatcgacat cggccagggc ccgccggagg agaaacgggt gccgtgggtg gtgctcgcgg
    22801 atccggaggg caacgagttc tgcgttctcg agcctcgaga gcagtacgag ggcaccggcg
    22861 cgatcgcggc ggtcgtcgtc gacgccctcg acccggagcg gctcgcgcgg ttctgggcgg
    22921 ccgcgctggg ctgggagatc ggcgtccggg aagagacgat cgtgggcctg cggccgccgg
    22981 acggtcgcgg cccctgggtc gagttcctcg ccacgaaaga ggacaagctg gagcggaacc
    23041 ggctgcgctt cgaggtcgcg ccggggccgg gcgggagccg ggcggccgaa gtccggcgcc
    23101 tgctggggct gggcgcgcta gggcgcggta cggcgagaca aggcgccgtg tccctggtgg
    23161 atccggaggg caacgagttc agcgtgctca cgccccgctg agtgtttcgc cccggttgcg
    23221 cggcggcgtc gaacgctgac ctgagcgaaa cacccgcgcc gtgggcaggc aacaaccggc
    23281 cgggaccgtt gaggtcatgg agacctatcg agcccggccc accctggtcc atcccggcga
    23341 agagacggcg gccgcttcgg cctggcgtgt ccggatccgc gtcgacgacc ggcccggcac
    23401 gctggccagg atcgcgatcc ggctggccga cctcgagtgc aacatcctcg ggctgtcggt
    23461 gctgccggtg cccggcggcg tgctcgacga aat
//
