LOCUS       NZ_LIWC01000002        20687 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Amycolatopsis sp. CB00013 scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_LIWC01000002
VERSION     NZ_LIWC01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Amycolatopsis sp. CB00013
  ORGANISM  Amycolatopsis sp. CB00013
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 1966077)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1966077)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905755.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:05:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,488
            CDSs (total)                      :: 8,430
            Genes (coding)                    :: 8,383
            CDSs (with protein)               :: 8,383
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 17 of 47
            Pseudo Genes (incomplete)         :: 38 of 47
            Pseudo Genes (internal stop)      :: 1 of 47
            Pseudo Genes (multiple problems)  :: 9 of 47
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 731969
            Orig. end                         :: 752656
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIWC01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20687
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="3"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20687
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20687
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10687](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10687)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    780..794
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.96"
                     /tool="antismash"
     misc_feature    838..853
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.05"
                     /tool="antismash"
     misc_feature    840..854
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(842..853)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            990..2090
                     /locus_tag="AMK34_RS13485"
                     /old_locus_tag="AMK34_13375"
     CDS             990..2090
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441636.1"
                     /locus_tag="AMK34_RS13485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13375"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_005165317.1"
                     /transl_table=11
                     /translation="MGRPIRTRRQATLASLAAELGVSRTTVSNAYNRPDQLSPELRRRV
                     LETARRLGYPGPDPVARSLRTRKAGAVGLLLTENLSYAFRDPAAVGVLEGLALACEDAG
                     VGLHLVPASPGREDVAAVHRAGVDGFVVYSVPDDDPHLGAVLERPVPTVIVDQPRVDGV
                     DRVGPDDAAAVTAMAEHLISLGHRQIGVLCMRLARERNDDFVSIQRQSAAHFHVQRIRL
                     EALAAAFSAAGVDWATVPVVERFDHTVDDGASAARQLLDAYPQVTAVICTSDILALGAL
                     AEAERRGLRVPQDLTVTGFDGITEAERSGLTTVHQPVLEKGKAAGKLLLSSADRVGPKV
                     ITLQTELRVGRTSAPPRTAEERWFGP"
     misc_feature    complement(1001..1018)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            2142..2633
                     /locus_tag="AMK34_RS13490"
                     /old_locus_tag="AMK34_13380"
     CDS             2142..2633
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020641910.1"
                     /locus_tag="AMK34_RS13490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13380"
                     /product="carbonic anhydrase"
                     /protein_id="WP_073845557.1"
                     /transl_table=11
                     /translation="MTSIDVLLKRNQELGDVTPGDRSSPRPSLHVTILTCMDARIRVFE
                     IFGMIQGEAHILRNAGGVVTDDMIRSLALSQRKLGTREVLIVQHTDCGLSMVTEDDFKD
                     ELEAASGLRPTWSVEAFRVVEDSVRRSVQRVRRSDFLAHTDNVRGFVYDVKLGRLTEVE
                     "
     gene            2652..3527
                     /locus_tag="AMK34_RS13495"
                     /old_locus_tag="AMK34_13385"
     CDS             2652..3527
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165321.1"
                     /locus_tag="AMK34_RS13495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13385"
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="WP_037335292.1"
                     /transl_table=11
                     /translation="MGVDADVLTEWFDEVGRDLPWREPECSAWGVLVSEIMLQQTPVAR
                     VQPIWLEWMARWPVPSALAASSQGEVVRAWGKLGYPRRALRLHAAAAVIAAEHGDVVPS
                     DVDTLLALPGIGAYTARAVAAFAYGKRAPVVDTNVRRVVARAVHGAGDAGPPSNTRDMA
                     DVEALLPPEDAPAAKLSAALMELGALVCTARSPRCADCPIYEDCAWQRAGKPAYAGPAK
                     QVQKFAGTDRQVRGLLLDVLRGSEGPVEKARLDLVWDESGQRDRCLDSLLVDGLLEQTR
                     DGLFALPGEH"
     misc_feature    2673..2688
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            3616..4578
                     /locus_tag="AMK34_RS13500"
                     /old_locus_tag="AMK34_13390"
     CDS             3616..4578
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028566.1"
                     /locus_tag="AMK34_RS13500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13390"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_143202448.1"
                     /transl_table=11
                     /translation="MADFDRRTALKGGLTVSAVGLLGTATISAADAASGVAEPKIYDTT
                     AWNARPPAGAIEVQNHKPTYIVVHHTVDPGNVTDYTLEHAFWASRSIQNFHMDTRGWID
                     TGQQFTNSRGGHITEGRHRSLEILRGGTRHVLGANVGNNNSTCIGIENEGLYSKEDVTP
                     ALWDSLVKLVAYIASQYGISPEFIKGHRDFNSTECPGTVLYNRLPELRTEVGKLLGTAS
                     PKVDLPEWPLLKPGDSGPRVRTAQELLRARGFAVPVDGLFGQSTKDAVAAVAARNGLER
                     DTCGATAATDETGFLGSDVWPLIVGSGTDPRALKARLAG"
     misc_feature    complement(3617..3631)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(4523..5677)
                     /locus_tag="AMK34_RS13505"
                     /old_locus_tag="AMK34_13395"
     CDS             complement(4523..5677)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337737.1"
                     /locus_tag="AMK34_RS13505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13395"
                     /product="MFS transporter"
                     /protein_id="WP_073845558.1"
                     /transl_table=11
                     /translation="MLSLPALLALTTTVFLGCLAEVLPAGLLLGMSEDLGVSPSATGQL
                     VTVYAITTAVTAIPLTGATLRVPRKRLLLALIFGFLATNLVIAVSSSYPLILATRIASG
                     ALTGVMWSLVAGYAMRLAPPGLTGRALAVAMSGTPIGFALGVPAGTALGEFADWRWAFA
                     AMALISVPLLAWVSVAVPAVPAERTEVTRPLAASRLPGMRPVLATVALFSLGHNVAYTY
                     IGPVLAGLDAAPMLGAVLLVFGCATVGGLVAAGSALDSRPRAVLVSCSAVTAAAIVLLG
                     VGDGVHGLVLVAAALWGLGFGGAPTAFQAVTALLAGPTADAAQSLTIAAWNGAVAGGAL
                     VGGLLLPLGTSSLPWCAAVLILAPLLFSRRVVPSAPADRCRSRR"
     gene            5844..7283
                     /locus_tag="AMK34_RS13510"
                     /old_locus_tag="AMK34_13400"
     CDS             5844..7283
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337738.1"
                     /locus_tag="AMK34_RS13510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13400"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_073845559.1"
                     /transl_table=11
                     /translation="MTVRIRWQEPLCTALLATTMLGACPASAVAKPAPGSDGYVHVSPD
                     GTVLGPDPYYPKDGNGGYDVDRYSLALDYAPYSMFLSGKATITATATQELDRFDLDLRG
                     LTVRSVTVDGMAATFRREGEHELVITPRTPLADGARFTVVVGYDGRPEPIATARGRVGW
                     LATYGDSAVATGQPRSAMTWFPVNGTEVDKATLRVSVTVLDEFSVLGNGFQVSDVHAGV
                     GRHTVTWSEETALAPSTAMLGIGRWEVERITLPGGRTAINAYHPCAVDKRKIGGRLPEV
                     LEFLTGKFGDYPQSAAGGLFLDRSLGYTHGAQTRPVYGRAATIADLVYASAYQWWGAGV
                     SGKMWRDALMPESIARYAVWLWDEKNGVDPDRRYREMVTKVRDDAAFWAPKLTDPGKGT
                     EFAPTAKAVLMVHALRRLVGDDAFFQILAGFPVINPQGNQNWHDFELYVSAMTQRDLGE
                     FNHAWLDGTVRPPDSLLFPGS"
     gene            complement(7711..8688)
                     /locus_tag="AMK34_RS13515"
                     /old_locus_tag="AMK34_13405"
     CDS             complement(7711..8688)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337739.1"
                     /locus_tag="AMK34_RS13515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13405"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_073845561.1"
                     /transl_table=11
                     /translation="MTKEFDVVQLDVHHLRVIRAIADTGSLSRAAIALGVTQPAVSAQL
                     KRLENMLGYQLFDRCEGGVTPTPMGELLLRRTAALLPQLDKLLEDIEQRVCPSGPPAVV
                     RVAAVASALVACLPSLVTRLWPEVSEVQVVHDDHPERLLPLLAQRRAELALVKDYPGYE
                     LEIPANVDTAVVVTEPTFVLLPAFHPLAREKVVDLCDLRDESWVMVSDSSAATFTKYFA
                     DTCARHGFTPSFTHQVTSQQVALLVVKAGAIGLSQPICDPGDHGVVTRPLRGDVLPRRH
                     VLAWNKETFVAGRREELLSAVVDAYWAEARTAPVYAEYLAGPRE"
     gene            complement(8685..9998)
                     /locus_tag="AMK34_RS13520"
                     /old_locus_tag="AMK34_13410"
     CDS             complement(8685..9998)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165331.1"
                     /locus_tag="AMK34_RS13520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13410"
                     /product="cytosine permease"
                     /protein_id="WP_073845562.1"
                     /transl_table=11
                     /translation="MEHDDFSLRRVPAERRYSWVSVALQRFGQVSSFHQFLLGAVLGFG
                     MTFWGAVLAITIGSVLLEIITILMGVAGTREGLSTSVLARWAGFGTGGSSLVGLLMTVS
                     LAGWFGVQNDVFAHGLHALMGGPPVWVWALAGGALVTAIVVFGFHAMAWTAYLTVPAFL
                     ALAGFSIISALGDHSLPALMAEPPPGPSMSLAQGTTLVAGAFIMGAIMTPDMTRFNRTA
                     SDVVKQTLVSVTLGQYLIGLIGVLLAHAAKSADVVGIITSSSGVLGTLILVTAILKIND
                     WNLYSSSLGLVNAVQVLLSRRLDRTTATLLLGGLGTVLSAIGILDHFTTFLTWVGVLTP
                     PVAGVVIAEYYVVRRWKPELDATRASGELPPTCPSWVPAALICWAAGAAVGVWLPWGIP
                     TVNSVFAAFLLYVLLGRRTTAAAVPAATTSSGGSKTRS"
     gene            complement(10001..10687)
                     /locus_tag="AMK34_RS13525"
                     /old_locus_tag="AMK34_13415"
     CDS             complement(10001..10687)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337741.1"
                     /locus_tag="AMK34_RS13525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13415"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_038520806.1"
                     /sec_met_domain="CDPS (E-value: 1.7e-77, bitscore: 256.9,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPLPLTEHCADPLARAEHVCLGVSPFNSHFTVERIADLARWAM
                     SAFRGFHFFVPDGPSAFTLEALGYDPVRAAQKAQRQGNYTRNKIVRALQQVCPSDPHTL
                     ILDAAALEADSAYLGLLSEAHQRFATDPEFAEQCLGATGWVLDRRLPEGEHPTRDQLRS
                     AVRYFLAELPMFVGTVAVAGVESSVFAYHQRVGFLERLYRGELSWRPLPGQGFVVLEQA
                     VPERVE"
     gene            10847..11800
                     /locus_tag="AMK34_RS13530"
                     /old_locus_tag="AMK34_13420"
     CDS             10847..11800
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337742.1"
                     /locus_tag="AMK34_RS13530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13420"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_038520809.1"
                     /transl_table=11
                     /translation="MEIQVRHLRVICEIAAAGSLNRAAAGLGLGQPALSHQLRRIERMV
                     GGPLFHRDQHGVRPTELGALILRRARAIVLTFDELEHDFHRQEPETGESIRIGWNDSAI
                     TGSLLGGLRDLRPGEPFRTRADTSRTRLLAQVANRGIDLALIMICGRRGLPVPPEVRTL
                     TLVEEPSFVAIPAEHPLAGEEEIELAELAGEDWIVSSGGDGCRVVFREMCLAHGFDPRI
                     THDVDIDTAREDLVSGGYGVGLVQPTRPPADGLAIRPLAGAPMCVRHVLAWREDGPCAH
                     GVPELATEARAGYWRLAERTASYRSWLHRHGRVAAG"
     gene            11893..12243
                     /locus_tag="AMK34_RS13535"
                     /old_locus_tag="AMK34_13425"
     CDS             11893..12243
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028559.1"
                     /locus_tag="AMK34_RS13535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13425"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_037335273.1"
                     /transl_table=11
                     /translation="MLPLITRTELLSRMESGSVVVVDTMPVAYFDKEHLPEARNIPGFP
                     YERAAEFTDRLAPVVLPDKAAAIVVYCANTPCRNSEFVGRRLLELGYTNVRKYREGIED
                     WVANDLPTWSSS"
     gene            12256..12690
                     /locus_tag="AMK34_RS13540"
                     /old_locus_tag="AMK34_13430"
     CDS             12256..12690
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337744.1"
                     /locus_tag="AMK34_RS13540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13430"
                     /product="thioredoxin family protein"
                     /protein_id="WP_038520812.1"
                     /transl_table=11
                     /translation="MSKVKRFVCVLAGALALVTGFGGGVASAAPKAENVMTVTSANYAE
                     VMDISKQKLVIMDFGATWCPPCRQMKPVIERLAGEYGGRFLLGEVDVDRSRDLSTRYNI
                     RYLPTLVGVRNAAELPSSRNIGYPGEARLRAWIDAQLAKG"
     gene            complement(12672..13469)
                     /locus_tag="AMK34_RS13545"
                     /old_locus_tag="AMK34_13435"
     CDS             complement(12672..13469)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-117). E-value:
                     1.2e-21. Score: 69.4. Matches aSDomain:
                     nrpspksdomains_AMK34_RS13545_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337745.1"
                     /locus_tag="AMK34_RS13545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13435"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_143202449.1"
                     /sec_met_domain="PF00561 (E-value: 1e-17, bitscore: 61.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3e-18, bitscore:
                     64.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGSLVVIQRDGLVTFGGDGPPIVLLHGLMGRATTWWRVARRLEP
                     YGRVHGLDARGHGRGPRGGPWRTERFTDDVAEMLRTFDEPAVLIGHSMGGLHAWVTAAR
                     HPELVRAVVCEDFAPDQRGRTVDTWRGYFESWPVPFRSLAHVREFFGDTGDYFIECVEE
                     REDGYHLIASLTDLYEIAAEWGRRDFWEFVERVKCPLLAIEGERTAMPHGQQAELAARV
                     PGGLGRHIVVQGAGHVVHDEAPETYLGAVEAFLSEVIGQPFAS"
     aSDomain        complement(13119..13409)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK34_RS13545_Abhydrolase_1.1"
                     /evalue="1.20E-21"
                     /label="AMK34_RS13545_Abhydrolase_1.1"
                     /locus_tag="AMK34_RS13545"
                     /protein_end="117"
                     /protein_start="20"
                     /score="69.4"
                     /tool="antismash"
                     /translation="PPIVLLHGLMGRATTWWRVARRLEPYGRVHGLDARGHGRGPRGGP
                     WRTERFTDDVAEMLRTFDEPAVLIGHSMGGLHAWVTAARHPELVRAVVCEDF"
     CDS_motif       complement(13158..13217)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK34_RS13545_0001"
                     /evalue="8.20E-05"
                     /label="NRPS-te1"
                     /locus_tag="AMK34_RS13545"
                     /protein_end="104"
                     /protein_start="84"
                     /score="15.2"
                     /tool="antismash"
                     /translation="PAVLIGHSMGGLHAWVTAAR"
     misc_feature    complement(13455..13457)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13468..14910
                     /locus_tag="AMK34_RS13550"
                     /old_locus_tag="AMK34_13440"
     CDS             13468..14910
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028556.1"
                     /locus_tag="AMK34_RS13550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13440"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_073845565.1"
                     /transl_table=11
                     /translation="MRSRVPAAGLVLGVVCALIIGCTADPPPATPPPPPPMNPAPGASG
                     AGDPYYPMDGNGGYDATEYQVGITYDPAKGRLDGDTTVIAKATQDLNRYNLDLRGLTVQ
                     SVEVDGKPAKFAREGEFELVVTPAEPIRNGTSFRTKVLYGGDPSATPKAGGSENGWQKS
                     KDGGAFIVGEPHSASFWYPVNETPRDKAMFTLNARVPDGWTVISNGREIQKTAANGWTT
                     TSWQERTPVAAYLTTVAIDKFTVDRMALPDGTPVVNAYAPGAEDRRDTGRRLPEIIGFL
                     SSKFGPYPVDAAGGIYLDEDIHFSLETQTRPTYAKWADLITVVHETAHQWFGDSVTLNS
                     WSDICLNECLASYAQWLWQESRDNENLDDRYRAALEIMRGSTDFWKPKLVGMGAGQEFH
                     GVYDKGILAVHALRRKIGEGAFARLLKEWPAAHRNANASWADFEAFTIKLSEQDLRPFF
                     DAWFHGTTIPPDAELLPGTLRG"
     misc_feature    13759..13761
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15081..16283)
                     /locus_tag="AMK34_RS13555"
                     /old_locus_tag="AMK34_13445"
     CDS             complement(15081..16283)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165347.1"
                     /locus_tag="AMK34_RS13555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13445"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_241832765.1"
                     /transl_table=11
                     /translation="MADTKILISGASVAGPALAFWLTRYGFQVTVVERAPSLRPGGQAV
                     DLRGTAKEVARRMGLDERIRAACTDTKGETLVDRKNRTKATIRADDFDGDGVVAEIEIL
                     RGDLTEVLYEATRERTEYVFGDRITALDERADGVGVTFASGSRATYDLVIGADGLHSGV
                     RALAFGEESRFVRHLGSYLAFFTVPNRLGLRNWAVGYDDVGRAAGIRGVRDGDEAMAYF
                     GFASPKIDYDYRDVDAQKALVRRFATGMEWEAPWLLDRMDEAPDFYFDSCAQVIMDSWS
                     RGRVGLLGDAAFCPSPLSGQGTSLAFVGAYVLAGELAAGLDTGLKRYEAVMREFVEKTQ
                     ELGRENAESIFAKSRTGLRMRYLAMRVMRLKPFAALASRKMRDVVNGIALPDYPAPHSE
                     D"
     misc_feature    complement(16317..16328)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.15"
                     /tool="antismash"
     gene            16345..16653
                     /locus_tag="AMK34_RS13560"
                     /old_locus_tag="AMK34_13450"
     CDS             16345..16653
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084240.1"
                     /locus_tag="AMK34_RS13560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13450"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_038520818.1"
                     /transl_table=11
                     /translation="MAVVKINAIEVPEGAGPELEKRFAARLHAVDDQPGFLGFELLRPV
                     SGESRYFVYTKWESEEAYQAWASGPAREAHAGERAKPVSTGANLLEFEVVQASKPGE"
     gene            16646..17458
                     /locus_tag="AMK34_RS13565"
                     /old_locus_tag="AMK34_13455"
     CDS             16646..17458
                     /EC_number="2.3.1.286"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337749.1"
                     /locus_tag="AMK34_RS13565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13455"
                     /product="Sir2 family NAD-dependent protein deacetylase"
                     /protein_id="WP_073845569.1"
                     /transl_table=11
                     /translation="MSELERAAELIDGAGALLVCAGAGMGVDSGLPDFRGDEGFWKAYP
                     PYERLGISFVELADPRHFAEDPKLAWGFYGHRLALYRATVPHDGFRLLSSWGARKPGGT
                     RAFTSNVDGQFQKAGYPHVAEAHGSIHHLQCLERCTKEIWSADDVEVPIDEDTMRARTP
                     LPSCPRCGGLARPNILMFGDYDWLGQRSQAQLDELNAWRRAHRDLVVVELGAGQAVPTV
                     RRYSELASAATGALVRINPREPGIRHGRGVSLATNGLETLEALDALLS"
     gene            complement(17451..18281)
                     /locus_tag="AMK34_RS13570"
                     /old_locus_tag="AMK34_13460"
     CDS             complement(17451..18281)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028552.1"
                     /locus_tag="AMK34_RS13570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13460"
                     /product="hypothetical protein"
                     /protein_id="WP_073845571.1"
                     /transl_table=11
                     /translation="MRKLWGVLALSLLAACVPGQLPPSEAKSALGFAARPGEANAFGAQ
                     DPVAEIQRLFRPGPGRTGVALTRAGRTAIGVGFREFPGESRSDPIAWVSGDGGTREIVL
                     PQDRPGHWAPTAIAADGERVLVTAALGGDVRVWASGDAGATWTVSQVLVRASDVWFSTA
                     LRVGGKWLLAGGSAAGALVVTGEPDAWEIAPLGDGRILGGTVGKAGEPVLFGDHVEWNR
                     GKTSNRSCSVVWVGQGGWQRGELGCPAGRLTAAMTLDDGRVVLKGDRDLWVRPS"
     gene            complement(18307..19335)
                     /locus_tag="AMK34_RS13575"
                     /old_locus_tag="AMK34_13465"
     CDS             complement(18307..19335)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337750.1"
                     /locus_tag="AMK34_RS13575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13465"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_073845572.1"
                     /transl_table=11
                     /translation="METAAPARSIGILDGMVIEERPVRPAARPGAGRKLVSGLLIAAVV
                     PFAVLTGLRLVGYDGNTYTIAALALTPYAGIATLVLGVLALVLRRWWTAVVALVLTCTI
                     ASMVLPRAFANEQRALDGKHVRVLASNMLGGGADPARIVGYVKEHQVDVLSLTELTPEA
                     ITALDRAGLFQVLPYHVLHPAEWASGSGLVSKYPLTPLKLSGDSDYKQPSAGVDLGDGV
                     RVEVVAVHPSAPMWDRHEWVAEAKDLPYADAEHDIRILAGDFNASLDHALFRELLTRGY
                     VDAADELGKALEGTWTNGIAPPVAIDHVLADKRTAIADFKVLETPGSDHDAVYAEIVLP
                     GK"
     gene            19473..20450
                     /locus_tag="AMK34_RS13580"
                     /old_locus_tag="AMK34_13470"
     CDS             19473..20450
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028550.1"
                     /locus_tag="AMK34_RS13580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_13470"
                     /product="daunorubicin resistance protein DrrA family ABC
                     transporter ATP-binding protein"
                     /protein_id="WP_038520829.1"
                     /transl_table=11
                     /translation="MTHAIRAEGLVKHYGETKALDGVDLEVPAGKVVGVLGPNGAGKTT
                     AVRILATLIRPDRGHASVFGYDVVKNPMAVRSMIGLTGQYASVDEDLSGTENLVLIGRL
                     LEFSRADAKKRAADLLERFELTDAAGRAIKTYSGGMRRRLDLAASLVGRPKVLYLDEPT
                     TGLDPHARNEVWAVVRTLVADGTTVLLTTQYLEEADQLADTITVFDHGHVVANGRADEL
                     KRRTGGQTLQVRPSALADLDAVERILAGLTGVRPNRDDDTGLLTAPVADPVLLSTLVRK
                     LDEAGITADELALRLPSLDEVFLALTGKKTDESTKDATPEGSLV"
ORIGIN
        1 cggggtggtg gtctgcgcgt tgttgatcag ggccttgacc tgcttgccgg agatcagctg
       61 cttgacctcg ttgagcgcgg cggcgggcac gtcctgctcc gcttccacgg cctcggcgaa
      121 ggcgggcgga gtcgcgtcgg tgaccttcgc gctgtcgagc aggtagtgcg cgacgggctc
      181 ggtcgcgacg accttggcgt tcgaggcgcc caggcccgag accttcttca gcagttcctg
      241 ggtcttgccc ttgaacgcgg tcgcgttggc ggtgaaggcg tccttcgagg cgggctggat
      301 ctccccgagc ttcgcggcga cctggtcggc gatcttctcg acgccgggga ggctgtacca
      361 gacgtgctcg ttctcgttgc cggtcgcggc gatgtcgacg gcgaccagct tctgcgcgcc
      421 ggtggcctgg tcggcgagct tcgagaagaa ctcgtcgtag ccgccgccgt tggacagcgt
      481 cagcttcgcg ttcttcgcgg cgatggcgtc gctcgcggtg gtctcgtagg agtgcgggtc
      541 ggccgacggg tcgtggatga tcgaggtgac ctcgaccttg tcgccgccga cggcggtcac
      601 gacgctgccc cagacgtcgg tcgaggcgac gaccttgatc ttctcgccac ccgggttcgc
      661 ggcggacgcg ttcggcgaac cggagcccgt cgacgccttg tcgctcgacg cgcaagccgt
      721 cgcgccgagc gcgaggacgg ccagggccga cacggccgcg aaaacactct tagtacggcg
      781 ggaattcatt tactgcactc ctgcggatgc ccaggccagg tgtccccaat gccgggtaat
      841 ggaaaccgtt gtcagattca actgtacccc atccggatga ccatgttccc cgtccaggcg
      901 cgagctgtac ccagggtcac tctgaatcga gacctgccac acgtcgggtg atgcttctgc
      961 aaaacgttct gaaccgttac ggtttgcgga tgggccgtcc tatccgcacc aggaggcagg
     1021 cgacactggc gtcgttggcc gcagagctcg gtgtgtcgag gaccaccgtc tccaacgcct
     1081 acaaccgacc cgaccagctg tcccctgagc tgcgccgccg cgtcctcgag accgcgcgcc
     1141 gcctcggcta cccgggcccg gacccggtgg cccgttcact gcggacgcgc aaagccggcg
     1201 ctgtcggtct tttgctcacc gaaaacctgt cctacgcctt ccgcgacccc gccgccgtcg
     1261 gcgtgctcga agggctcgcg ctggcctgcg aagacgcggg cgtcggcctg cacctggtcc
     1321 cggcgagccc gggccgggaa gatgtcgcgg ccgtgcaccg cgccggcgtc gacggcttcg
     1381 tcgtctactc ggtgcccgac gacgaccctc atctgggcgc cgtgctggag cgcccggtgc
     1441 cgacggtgat cgtcgaccag ccgcgcgtgg acggcgtcga ccgggtcggc ccggacgacg
     1501 cggccgcggt gaccgccatg gccgagcacc tcatctcgct gggacaccgg cagatcggcg
     1561 tgctgtgcat gcggctggcc cgtgagcgca acgacgattt cgtctccatc cagcggcaga
     1621 gcgccgccca cttccacgtc cagcggatcc ggctggaggc gctggccgcc gcgttctcgg
     1681 cggccggggt cgactgggcg accgtgccgg tggtcgagcg cttcgaccac accgtggacg
     1741 acggcgcgtc ggccgcgcgc cagctgctcg acgcgtatcc gcaggtcaca gccgtgatct
     1801 gcacctcgga catcctcgcc ctcggcgcgc tggccgaggc ggagcgccgc gggctgcggg
     1861 tgccgcagga tctgacggtc accggcttcg acggcatcac cgaggccgag cgttccgggc
     1921 tcaccacggt ccaccagccg gtgctggaga agggcaaggc tgcgggcaag ctgctgctca
     1981 gctccgccga ccgggtcggg cccaaggtga tcacgctgca gacggaactc cgggtcgggc
     2041 gcacgtccgc gccgccgcga acggccgaag aacgctggtt cgggccgtga tctgcgtccg
     2101 cacgcgttgc cgtcgccccg cgcgtcggtt ccaatgaaca cgtgacctca atcgacgtac
     2161 tgctcaagcg aaaccaggag ctgggtgatg tcactcctgg tgaccgctcg tctccgaggc
     2221 catcgctcca cgtgacgatc ctgacctgca tggacgcccg tatccgggtg ttcgagatct
     2281 tcggcatgat ccagggtgaa gcgcacatcc tgcgcaacgc gggcggcgtc gtcaccgacg
     2341 acatgatccg ctcgctcgcg ctcagccagc ggaagctcgg cacgcgcgag gtgctgatcg
     2401 tgcagcacac cgactgcggc ctgtccatgg tcaccgaaga cgacttcaag gacgaactcg
     2461 aagccgccag cgggctgcgg ccgacgtggt cggtcgaggc gttccgggtg gtggaggaca
     2521 gcgtgcgccg gtcggtgcag cgcgtgcggc gcagtgactt cctggcgcat accgacaatg
     2581 tgcgcggttt cgtctacgac gtaaaactag gccgcctgac cgaggtcgag taagggtttt
     2641 aagctgactc ggtgggcgtc gacgcggatg tgctgaccga atggttcgac gaagtggggc
     2701 gcgacctgcc ctggcgtgag ccggaatgct ccgcctgggg cgtgctcgtc agcgagatca
     2761 tgctgcagca gaccccggtc gcgcgcgtcc agccgatctg gctcgaatgg atggcgcgct
     2821 ggccggtgcc gtcggcgctg gcggcgtcgt cgcagggcga ggtcgtgcgt gcctggggca
     2881 aactcggcta tccgcggcgc gcgctgcggc tgcacgccgc ggcggccgtc atcgccgccg
     2941 aacacggcga cgtcgttccg tccgatgtgg acactctgct cgcgttgccg gggatcggcg
     3001 cgtacaccgc ccgcgcggtc gcggccttcg cctacggcaa acgcgcgccg gtggtggaca
     3061 cgaacgtccg tcgcgtggtc gccagagcgg tgcacggcgc gggtgacgcc gggccgccgt
     3121 cgaacacccg cgacatggcc gacgtcgagg cgctgctccc gccggaggac gcgcccgccg
     3181 cgaaactctc ggcggcactg atggaactcg gcgcgctcgt ctgcacggcg cgctcgccgc
     3241 gctgcgcgga ctgcccgatc tacgaagact gcgcgtggca gcgcgcgggc aaacccgctt
     3301 acgccgggcc cgcgaagcag gtccagaagt tcgccggcac cgaccgtcag gtgcgcggtt
     3361 tgctgctcga cgtcctgcgc ggcagcgaag ggccggtcga gaaggcgcgg ctcgatctcg
     3421 tgtgggacga atccgggcag cgtgaccgtt gcctcgactc cctgctcgtc gacggcctcc
     3481 tcgaacagac ccgggacggc ctgttcgcgc tgcctggcga acactaacgc attacgacaa
     3541 aagttggtca atggttgtca tcggcgcgat ggcgggttag ttttccggcc aacgcgcatg
     3601 atgggagtta cgcccgtggc cgacttcgac cgacgtaccg cgctcaaggg cggcctgacg
     3661 gtaagcgccg tcgggctact ggggacagcg acgatttccg ccgccgatgc ggcgtctggg
     3721 gtggcagaac ccaagattta cgacacgacg gcctggaacg cccgcccgcc ggccggggcg
     3781 atcgaggtgc agaaccacaa accgacgtac atcgtcgtgc accacacggt cgatccgggg
     3841 aacgtcaccg actacacgct cgaacacgcc ttctgggcgt cgcgttcgat ccagaacttc
     3901 catatggaca cccgtggctg gatcgacacc ggccagcagt tcacgaacag ccgcggcggg
     3961 cacatcaccg aagggcggca ccgcagcctg gagatcctgc gcggcgggac ccggcacgtg
     4021 ctgggcgcga acgtgggcaa caacaacagc acctgcatcg gcatcgagaa cgagggcctc
     4081 tacagcaaag aggacgtcac gcccgcgctc tgggactcgc tggtgaagct ggtcgcgtac
     4141 atcgcgtcgc agtacgggat ctcgccggag ttcatcaagg gacaccggga cttcaactcg
     4201 accgaatgcc cgggaaccgt gctgtacaac cggcttcccg agctgcgcac ggaggtcggc
     4261 aagctgctgg gcaccgcgtc gcccaaggtg gacctgccgg agtggccgct gctcaaaccc
     4321 ggcgactccg gacctcgcgt gcggacggcg caggaactcc tgcgggcacg cggtttcgcc
     4381 gtcccggtcg acggcctgtt cggacagtcc acaaaggacg cggtcgccgc ggtggcggcc
     4441 cgcaacgggc tggagcgcga tacctgcggt gcgacggcgg cgaccgacga gaccgggttc
     4501 ctcggctccg acgtctggcc gctcatcgtc ggctccggca ccgatccgcg ggcgctgaag
     4561 gcacgactcg ccggctgaac aggagcggcg cgaggatcag cacggccgcg caccacggga
     4621 gcgacgacgt tcccagtggc agcagcagcc cgccgacgag ggctcccccg gcgacggcgc
     4681 cgttccaggc cgcgatcgtg agcgactggg cggcgtcggc cgtggggccc gcgagcaagg
     4741 cggtgacggc ctggaacgcg gtcggcgcgc cgccgaatcc gaggccccac aaggccgcgg
     4801 cgacaagcac gagtccgtgg acaccgtcgc cgacccccag caggacgatg gcggcggcgg
     4861 tcacggcgga gcacgacacg agcaccgcgc gcggacggct gtcgagcgcg gagccggccg
     4921 cgaccagccc gcccaccgtg gcgcagccga acaccagcag caccgcgccc agcatcggtg
     4981 ccgcgtcgag cccggcgagc accggaccga tgtaggtgta ggccacgttg tgccccaacg
     5041 agaacagcgc caccgtcgcc aatacgggac gcattcccgg cagcctcgac gcggccagcg
     5101 ggcgggtgac ttccgtccgc tccgcgggta cggcgggcac cgcgacggaa acccaggcca
     5161 gcaacggcac ggagatcagc gccatcgcgg cgaacgccca gcgccagtcg gcgaattcgc
     5221 cgagcgcggt ccccgcgggc acgcccagcg cgaagccgat cggcgtgccc gacatcgcga
     5281 cggccagcgc gcgtccggtg agtcccggcg gggcgagccg catcgcgtaa cccgcgacga
     5341 gcgaccacat caccccggtc agcgcaccgg aagcgatccg tgtcgccagg atcagcggat
     5401 acgacgagga caccgcgatc accagattcg tcgccaggaa gccgaagatc agcgccagga
     5461 gcaagcgttt gcgcggcaca cggagggtcg ctcccgtgag cgggatggcg gtgaccgcgg
     5521 tcgtgatcgc gtagaccgtc accagctgcc cggtggccga cggcgagacg cccagatcct
     5581 cggacattcc cagcagcaat ccggcgggga gcacttcggc gaggcagccg aggaacaccg
     5641 tggtcgtcag cgcgagcagc gccgggaggg acagcatgcc tcgacgatct cttccgctgg
     5701 gtgacgcggg tagtccctgg cgggtatgcc gcgcggttat cggccgggat aacccggcgg
     5761 catgaccggc tggcagtgcc gcgcgccgcg cggacgtacg cacgatgacc gggcaccctc
     5821 cccgttagag agaaggctcg ttcatgaccg tgcggattcg gtggcaggag ccactgtgca
     5881 ccgcgttgct cgccaccacg atgctcggcg cctgcccggc ttcggcggtc gccaagccgg
     5941 cccccggcag cgacgggtac gtgcacgttt cacccgacgg caccgtcctc ggacccgatc
     6001 cttactaccc gaaggacggc aacggcggtt acgacgtcga ccgatactcc ctcgcgttgg
     6061 actacgcgcc gtactcgatg ttcttgagcg gcaaggcgac catcaccgcg accgcgaccc
     6121 aggagctgga ccggttcgac ctcgacctgc ggggtctcac cgtccgttcg gtaaccgtcg
     6181 acggtatggc cgcgacgttc cgccgggagg gtgaacacga gctggtgatc acgccacgga
     6241 ccccgttggc cgacggtgcg cggttcaccg tggtggtcgg ttacgacggg cgtccggaac
     6301 cgatcgccac ggcgcgggga cgggtcggct ggctggccac gtacggcgat tccgccgtcg
     6361 ccaccgggca gccgcgttcg gcgatgacct ggttcccggt caacggcacc gaagtcgaca
     6421 aggcgaccct gcgcgtctcc gtcaccgtgc tggacgaatt ctccgtgctg ggcaatggtt
     6481 ttcaggtctc cgacgtgcac gccggcgtcg ggcggcacac cgtcacctgg tctgaggaaa
     6541 ccgcgctcgc gccgagcacg gcgatgctcg gcatcggccg ctgggaggtc gagaggatca
     6601 cccttcccgg tgggcggacc gcgatcaacg cctaccaccc gtgcgccgtg gacaagcgga
     6661 agatcggcgg gcggctgccg gaggtcctgg aattcctcac cgggaagttc ggcgactatc
     6721 cgcagtcggc ggcgggcggg ctgttcctcg accgctccct cggctacacg cacggcgccc
     6781 agaccaggcc ggtgtacggc cgcgccgcca cgatcgccga tctggtgtac gcgagcgcgt
     6841 accaatggtg gggagcgggg gtgagcggca agatgtggcg cgacgcgctg atgcccgagt
     6901 caatcgcgcg gtacgcggtg tggctgtggg acgagaagaa cggcgtcgat ccggatcgtc
     6961 gctaccgcga gatggtgacg aaggtgcgcg acgacgcggc tttctgggcg ccgaagctca
     7021 ccgatccggg caagggcacc gaattcgcgc cgacggccaa agcggtgctg atggtgcacg
     7081 cgctgcgccg tctcgtcggc gacgacgcgt tcttccagat cctggcgggc ttcccggtga
     7141 tcaatccgca gggaaaccag aactggcacg acttcgagct ctacgtctcc gcgatgaccc
     7201 aacgcgatct cggcgagttc aaccacgcgt ggctggacgg cacggtgcgg ccgccggact
     7261 cgctgctctt tcccgggagc tgaacgacct cgtgagtggt gaggacggtg ggttgcgaaa
     7321 gccactttcg caaccttcaa cgttgcgaaa gtggctttcg caacatcggc cgtgaccggg
     7381 cccggtaccg ccctggcgat catgtcgcga aagccacttt cgagacgtct gatgtcccga
     7441 aagtggcttt cgcgacacac cgccggtggt tctcttgagg ggtcgtgctc gcgggccggg
     7501 tcggcggtgg ggcgaaggct cccttcgccg cgtctaatcc ggtgaaggga gccttcaccc
     7561 cggtcacccg cccgcgccga ccatcccgcc cgccagcgcc cgtgtcgcga aacccacttt
     7621 cgcgacgcgt tcgacaggtg gaagagcgcg gtgacccctt ggtgtccctt gtggacggtg
     7681 ggccgcgcac cacacgtcac ctttgcctca ctactcacga ggcccggcca ggtattccgc
     7741 gtagacgggc gccgtccgcg cctcggccca gtacgcgtcg acgacggcgg agagcagctc
     7801 ttcccgccgt cccgccacga acgtctcctt gttccaggcg agaacatgcc tgcgcggcaa
     7861 cacatccccg cgcagcggcc gcgtcacgac gccgtggtcg cccggatcgc agatcggctg
     7921 ggacagcccg atcgcgcccg ctttgaccac caacagtgcc acctgctgcg aagtcacctg
     7981 atgggtgaac gacggcgtga aaccgtgccg cgcgcaggtg tcggcgaagt acttggtgaa
     8041 cgtggccgcc gatgaatcgg acaccatcac ccacgattcg tcccgcagat cgcacaggtc
     8101 gacgaccttc tcccgcgcca gcggatggaa agccggcagg aggacgaagg tcggctcggt
     8161 caccaccacc gcggtgtcca cgttcgcggg gatttcgagc tcgtaacccg gatagtcctt
     8221 gaccagcgcc aattccgcgc gacgctgggc cagcagcggc aacagccgct cgggatggtc
     8281 gtcgtgcacg acctgtacct cggagacctc cggccacaac cgggtcacca gcgacggaag
     8341 acacgccacc agcgcactgg ccaccgcggc cacccggacc acggcgggcg gaccgctggg
     8401 gcagacgcgc tgctcgatgt cttcgagcag tttgtccagc tgtggcagca aagcggccgt
     8461 gcggcgcaac agcagctccc ccatcggggt cggtgtcacg ccgccttcgc accggtcgaa
     8521 cagctggtag cccagcatgt tctccagccg tttgagttgc gcggaaaccg cgggctgggt
     8581 gacgcccagc gcgatcgcgg cacgggaaag gctgcccgtg tccgcgatcg cccggatcac
     8641 ccgcaggtgg tggacatcca gctgtacgac gtcgaactcc tttgtcacga acgggttttc
     8701 gacccgccgg aagaagtcgt ggccgcggga accgccgcgg ccgtggtccg tctgccgaga
     8761 agaacataca gcagaaatgc cgcgaaaacg gagttcaccg tggggattcc ccacggcagc
     8821 cagaccccca ccgccgcccc ggccgcccag cagatcagcg cggcgggaac ccaggacggg
     8881 caggtgggcg gcagttcccc cgacgcacgg gtggcgtcca gctccggttt ccagcgccgg
     8941 accacgtagt actcggcgat caccaccccc gccaccggcg gcgtgagcac gccgacccag
     9001 gtcaggaagg tggtgaagtg gtcgaggatg ccgatcgcgg agagcaccgt gccgaggccg
     9061 ccgagcagca gggtcgcggt ggtgcggtcc agccgccggg acagcagcac ctgcacggcg
     9121 ttcaccagcc cgagcgagga cgagtagagg ttccagtcgt tgatcttcag gatcgcggtg
     9181 accaggatca gcgtgccgag caccccggac gacgaggtga tgatcccgac cacgtcggcg
     9241 cttttcgccg cgtgcgcgag cagcaccccg atcaggccga tcaggtactg gccgagggtg
     9301 acgctgacca gggtctgttt caccacgtcg gacgcggtcc ggttgaaccg ggtcatgtcc
     9361 ggcgtcatga tcgcgcccat gatgaaggca cccgccacca gcgtggtgcc ctgcgccagc
     9421 gacatcgacg gccccggcgg cggctcggcc atcagcgcgg gcagcgaatg gtcgccgagc
     9481 gccgagatga tcgaaaaccc cgccagcgcc aggaaagcgg gcaccgtcag gtacgccgtc
     9541 cacgccatcg cgtggaagcc gaacacgacg atcgcggtga ccagcgcgcc gcccgcgagc
     9601 gcccacaccc acaccggcgg gccgcccatc aacgcgtgca gaccgtgggc gaagacgtcg
     9661 ttctgcaccc cgaaccagcc ggccaggctc accgtcatca ggagcccgac cagcgacgat
     9721 ccgccggtgc cgaacccggc ccagcgcgcg agcaccgaag tcgaaagccc ttcccgggtg
     9781 ccggcgaccc ccatcaggat ggtgatgatc tccagcagca cggaaccgat cgtgatggcg
     9841 aggaccgcgc cccagaacgt catcccgaaa cccagcaccg cgccgagcag gaactgatgg
     9901 aacgaggaaa cctgcccgaa ccgttgcagc gcgacggaaa cccaggagta gcggcgttcg
     9961 gcgggtaccc ggcgcaggga gaagtcgtcg tgttccacgc tcactccacg cgttccggga
    10021 cggcttgttc gaggacgacg aaaccttggc ccggcaacgg ccgccacgag agttcgccgc
    10081 ggtagagccg ttcgaggaag ccgacccgct ggtgataggc gaacacggag ctttcgacgc
    10141 cggccacggc gacggtgccg acgaacatcg gcagctcggc gaggaagtac cggaccgcgc
    10201 tgcgcagctg gtcacgggtg gggtgttcgc cttcgggcag gcgccggtcc agcacccagc
    10261 ccgtggcgcc gaggcactgc tcggcgaact ccggatcggt ggcgaaccgt tggtgcgcct
    10321 cggaaagcag gccgaggtac gcgctgtcgg cctccagcgc cgcggcgtcc agtatcaagg
    10381 tgtgcggatc cgaagggcag acctgctgta gcgcgcggac gatcttgtta cgcgtgtaat
    10441 tgccctgtcg ttgcgccttt tgcgcggcgc ggaccgggtc gtaaccgagc gcttcgaggg
    10501 tgaacgcgga cgggccgtcc gggacgaaga aatggaatcc ccgaaaggcc gacatggccc
    10561 agcgggcgag atcggcgata cgttccaccg tgaaatggct gttgaacggg ctgacgccga
    10621 gacaaacgtg ctcggcccgc gccagcggat cggcgcaatg ctccgtgagt ggcagtggtc
    10681 gcggcaagac ggctcctgat tcgcgtgatc tgcggggcgt cgaccgaacg tagccacggc
    10741 actcctgcgc gggtattgcc ggagaatgtt gtcaccgggt tatgagaaat cggctgtctc
    10801 tactttcggg ggtgccgggc gcgaaccggt cgcggtatac gaagtcatgg agattcaggt
    10861 tcggcatctt cgcgtgatct gtgagatcgc cgccgccggc agtctcaatc gtgccgcggc
    10921 cgggctggga ctcgggcaac ccgcgctcag ccaccagttg cgccggatcg agcggatggt
    10981 cggcggcccg ctgttccacc gcgaccagca cggggtgcgg cccaccgaac tcggcgccct
    11041 gatcctgcgg cgggcacggg cgatcgtgct caccttcgac gaactggagc acgacttcca
    11101 ccggcaggaa cccgagacgg gcgaatcgat ccggatcggc tggaacgaca gcgccatcac
    11161 gggttcactg ctcggcggcc tgcgcgacct gcgtcccggc gagccgttcc gcacgcgcgc
    11221 cgacacttcg cgcacgcggc tgctcgcgca ggtcgcgaac cggggcatcg acctggcgct
    11281 gatcatgatc tgcggccgtc gcggtctccc cgtgccgccg gaagtgcgga cgctgacgct
    11341 ggtcgaggag ccgtctttcg tcgccatccc cgcggaacat ccgctcgccg gcgaagagga
    11401 gatcgagctc gccgaactcg ccggggagga ctggatcgtg tcgagcggcg gcgacggctg
    11461 ccgggtggtg ttccgcgaaa tgtgtctcgc gcacggtttc gatccgcgga tcacccacga
    11521 cgtcgacatc gacaccgcac gggaagacct ggtcagcggc gggtacgggg tcgggctggt
    11581 ccagccgacc cggccaccgg cggacgggct ggccatccgg ccgctggcgg gcgcgccgat
    11641 gtgcgtgcgg catgtgctgg cgtggcggga agacggtcca tgcgcgcacg gggtcccgga
    11701 actcgccacc gaggcgaggg cgggctattg gcggctcgcc gaacggacgg cgtcgtaccg
    11761 ctcctggttg caccgccacg gaagggtggc cgccggataa cccctcggca tgccgaggcg
    11821 gcactagagc gtgtcccgcg aggcgtccga cgatgtgaat cgtcaatcac ggtcgccgaa
    11881 agaaggggca ccatgctgcc gttgatcacc cgtacggaac tgctttcccg gatggagtcc
    11941 ggttcggtgg tcgtggtcga cacgatgccg gtcgcctatt tcgacaagga acatctgccg
    12001 gaagcgcgca acattccggg tttcccgtac gaacgggccg ccgaattcac cgaccggctg
    12061 gcacccgtgg tgcttccgga caaggccgcc gcgatcgtcg tctattgcgc gaacacgccg
    12121 tgccgcaaca gtgaattcgt cggacggcgg ctgctggagc tcggatacac gaacgtccgc
    12181 aagtaccgcg aaggcatcga agactgggtc gcgaacgatc ttccgacctg gtcttcgtcc
    12241 tgaaaggaga tcgtcttgtc caaggtcaaa cgattcgtct gcgtgctggc cggtgcgctg
    12301 gcactcgtca ccggattcgg cggcggcgtg gcttcggccg caccgaaggc cgagaacgtg
    12361 atgacggtga cttcggccaa ctacgccgag gtcatggaca tctcgaagca gaagctggtc
    12421 atcatggact tcggcgcgac ctggtgcccg ccgtgccgcc agatgaaacc ggtgatcgag
    12481 cggctcgccg gtgaatacgg cgggcggttc ctgctgggcg aggtcgacgt cgaccggagc
    12541 cgtgacctgt ccacccggta caacatccgt tacctcccga cgctggtcgg cgtccgcaac
    12601 gccgccgaac tgccgtcgtc gcggaacatc ggttacccgg gcgaagcgcg gttgcgcgcc
    12661 tggatcgacg ctcagctcgc gaagggctga ccgatgacct cggagagaaa cgcttcgacg
    12721 gcaccgaggt aggtctccgg cgcttcgtcg tgcaccacgt gcccggcgcc ttggacgacg
    12781 atgtgccgtc cgaggccgcc gggcacgcgg gcggccagtt cggcctgctg gccgtgcggc
    12841 atcgcggtgc gttcgccctc gatcgcgagc agcggacatt tgacgcgttc gacgaactcc
    12901 cagaaatcac gccgtcccca ctcggccgcg atctcgtaca ggtccgtgag cgacgcgatc
    12961 aggtgatagc cgtcttcgcg ttcctcgacg cattcgatga agtagtcgcc ggtgtcgccg
    13021 aagaactcgc gcacatgggc cagcgaccgg aacgggaccg gccacgactc gaaatacccg
    13081 cgccaggtgt ccacggtccg gccgcgctga tccggcgcga agtcctcgca gaccacggcg
    13141 cggacgagtt cgggatgccg ggccgcggtg acccacgcgt gcaggccgcc catcgaatgt
    13201 ccgatcagga ccgcgggttc gtcgaaggtc cgcagcattt ccgcgacgtc gtcggtgaac
    13261 cgttcggtgc gccagggccc gccgcgcggc ccgcgtccgt gtcctcgcgc gtcgaggccg
    13321 tggacacgcc cgtacggttc gagccttcgc gcgacccgcc accacgtcgt cgccctgccc
    13381 atcagcccgt gcagcaggac gatcggtggc ccgtcaccgc cgaaagtgac caacccgtcg
    13441 cgctgaatca ccactaagct cccctccatg cgcagccgtg tccccgccgc cggtctggtc
    13501 ctgggggtcg tctgcgccct gattatcggc tgcaccgccg atcctcctcc ggccacgccc
    13561 cctccgccgc cgccgatgaa cccggcgccg ggtgcttcgg gcgcgggcga cccgtattac
    13621 ccgatggacg gaaacggcgg ctacgacgcg accgagtacc aggtcgggat cacttacgac
    13681 cccgcgaaag ggcgtctcga cggcgacacc acggtgatcg cgaaagcgac ccaagacctc
    13741 aatcggtaca acttggactt acgcggcttg acggtccaat ccgttgaagt ggacgggaaa
    13801 ccggcgaagt tcgcgcgcga gggcgaattc gaactggtgg tgacgcccgc cgagccgatc
    13861 cggaacggga cctccttccg caccaaggtc ctctacggcg gcgacccgtc ggcgacgccc
    13921 aaggcgggcg gcagcgagaa cggctggcag aagtcgaagg acggcggcgc gttcatcgtc
    13981 ggcgagccgc attcggcgtc gttctggtat cccgtcaacg aaaccccgcg cgacaaggcg
    14041 atgttcaccc tcaacgcccg cgtgccggac ggctggaccg tcatctcgaa cggacgcgag
    14101 atccagaaga ccgcggcgaa cggctggacg acgacgtcct ggcaggaacg cacccccgtg
    14161 gcggcgtacc tgaccacggt ggcgatcgac aagttcaccg tcgaccggat ggcgctcccg
    14221 gacgggacgc cggtggtcaa cgcgtacgcg ccgggcgccg aggaccggcg cgacacgggc
    14281 aggcggctgc cggagatcat cggcttcctg agctcgaagt tcgggccgta cccggtggac
    14341 gccgcgggcg gcatctatct cgacgaggac atccacttct cgctggagac ccagaccagg
    14401 ccgacctatg cgaaatgggc cgacctgatc accgtggtgc acgaaaccgc acaccagtgg
    14461 ttcggcgatt cggtgacgct gaattcctgg tcggacatct gtctcaacga atgtctcgcg
    14521 tcgtacgcgc aatggctgtg gcaggagtcg cgggacaacg agaacctgga cgaccgttat
    14581 cgcgccgcac tggagatcat gcggggcagc accgatttct ggaagccgaa gctggtcggc
    14641 atgggggcgg ggcaggaatt ccacggcgtc tacgacaagg ggatcctggc agtccacgcg
    14701 ctgcggcgga agatcggcga aggcgctttc gcgcggctgc tgaaggaatg gccggcggcg
    14761 caccggaacg ccaacgcgag ctgggcggat ttcgaggcgt tcacgatcaa gctttcggag
    14821 caggacctgc ggccgttctt cgacgcttgg ttccacggga cgacgatccc gccggacgcg
    14881 gaactccttc cgggcaccct gcgaggctga ccccacctca ccccgcattt agtcctctaa
    14941 atgcgggccg tgcgggcacc tcacccacgc actggcgcgt tgcgaaagcc actttcgcaa
    15001 ccttcaacgt tgcgaaagtg gctttcgcaa caccggcgga gcccacgcga ccagccgccg
    15061 cggcaccccc actcacgcat ttagtcctct gaatgcgggg ccgggtagtc cggcagggcg
    15121 atgccgttca cgacgtcccg catcttccgc gaggccaggg cggcgaacgg cttcagccgc
    15181 atgacccgca tcgccagata ccgcatccgc aaacccgtcc gcgacttcgc gaagatcgac
    15241 tccgcgttct cccgccccag ctcctgggtc ttctcgacga actcgcgcat gacggcttcg
    15301 tagcgtttca gcccggtgtc gagaccggcg gcgagttccc cggcgagcac gtacgcgccg
    15361 acgaacgcca ggctcgtgcc ctgcccggac agcggcgaag ggcagaaagc ggcgtcgccc
    15421 agcagcccga cgcggccgcg cgaccaggag tccatgatca cctgggcgca cgagtcgaag
    15481 tagaagtcgg gcgcctcgtc catccggtcc agcagccagg gcgcttccca ctccatcccg
    15541 gtggcgaacc ggcggaccag cgccttctgc gcatcgacgt cgcggtagtc gtagtcgatt
    15601 ttcggcgacg cgaacccgaa gtacgccatc gcctcgtcgc cgtcgcggac gccgcggatc
    15661 ccggcggccc ggccgacgtc gtcgtagccg acggcccagt tccgcaggcc gagccggttc
    15721 ggcacggtga agaacgccag gtacgagccg agatgccgga cgaaccggga ttcctcgccg
    15781 aaggccagcg cccgcacgcc cgaatgcagc ccgtccgccc cgatgaccag gtcgtaagtc
    15841 gccctcgaac cactcgcgaa ggtgacgccg acgccgtcgg cccgctcgtc cagcgcggtg
    15901 atccggtcgc cgaagacgta ctccgtccgc tccctggtcg cttcgtagag cacttcggtc
    15961 aggtcgccgc ggaggatctc gatctccgcg acgacaccgt cgccgtcgaa gtcgtcggcg
    16021 cggatggtgg ccttcgtgcg gttcttccgg tcgacgagcg tctcgccctt cgtgtccgtg
    16081 caggccgcgc ggatgcgttc gtcgagcccc atccggcggg cgacctcctt ggccgttccg
    16141 cgcaggtcga cggcctggcc gccgggacgc aacgacggcg cgcgctccac gacggtcacc
    16201 tggaagccgt accgggtgag ccagaaggcc aaggccggtc cggcgacgct cgctccggag
    16261 atgaggatct tggtgtcagc catcgcctgg aaggtcccac gcatcacatc gcggcgcaaa
    16321 acgatttcgt cgtaggctgg cggcatggct gtcgtgaaga tcaacgcgat cgaggtaccc
    16381 gaaggcgcag gccccgagct ggagaagcgg ttcgccgcgc ggctgcacgc cgtcgacgat
    16441 cagcccggtt tcctcggctt cgagctgctc cgcccggtct ccggcgagtc gcgctacttc
    16501 gtctacacca agtgggagtc cgaagaggcg taccaggcgt gggcgtccgg cccggcgcgt
    16561 gaagcgcacg cgggcgagcg cgcgaagccg gtctccacgg gtgcgaacct gctggaattc
    16621 gaggtcgtcc aggcttcgaa gccgggtgag tgaactcgaa cgagccgcgg aactgatcga
    16681 cggcgccggc gcgctgctcg tctgcgccgg tgccgggatg ggcgtcgact ccggcctgcc
    16741 cgatttccgg ggcgatgaag gtttctggaa ggcatatccg ccgtacgagc ggctgggcat
    16801 cagcttcgtc gagctcgccg acccgcgtca tttcgccgag gatcccaagc tggcctgggg
    16861 tttctacggg catcggctag cgctgtatcg cgccaccgtc ccgcacgacg ggttccgtct
    16921 cctgtcgtcc tggggagcac gcaaaccggg cggcacccgc gctttcacgt ccaatgtgga
    16981 cggacagttc cagaaggcgg gttatccgca cgtcgccgag gcgcacggct ccatccatca
    17041 ccttcagtgc ctcgaaaggt gcaccaagga gatctggtcc gcggacgacg tcgaggtccc
    17101 gatcgacgaa gacaccatgc gcgcgcggac cccgctgccg tcctgcccgc gctgcggcgg
    17161 tctcgcccgg cccaacatcc tgatgttcgg cgactacgac tggctcgggc agcgcagcca
    17221 ggcccagctc gacgagctga acgcgtggcg ccgcgcgcat cgcgacctcg tggtggtgga
    17281 actcggcgcc ggacaggccg tgccgacggt gcggcggtac tcggagctgg ccagcgccgc
    17341 gaccggcgcc ctggtgcgga tcaacccgcg tgaacccggg atccggcacg gccgcggtgt
    17401 ctccctcgcg accaacggcc tggaaaccct cgaagcgctg gacgccctgc tcagctaggc
    17461 cgcacccaca ggtcgcggtc gcccttcagc accacacgcc cgtcgtcgag ggtcatcgcg
    17521 gcggtgagcc gtccggccgg gcagccgagc tcaccgcgct gccagcctcc ctgcccgacc
    17581 cacaccaccg agcacgaccg attcgacgtc ttgccccggt tccactcgac gtggtccccg
    17641 aacagcacgg gctcacccgc cttgccgacg gtcccgccga ggatccggcc atcgccgagc
    17701 ggagcgattt cccaggcatc gggctcgccg gtcacgacca gcgcaccggc cgcggaacct
    17761 ccggccagca gccatttccc gcccacccgg agcgcggtgg agaaccagac gtcgctcgcc
    17821 cgcaccagca cctgcgagac cgtccaggtg gcgcccgcgt caccagatgc ccacacccgg
    17881 acgtctccgc cgagggccgc ggtcacgagc acccgctcgc cgtcggcggc gatcgcggtc
    17941 ggcgcccagt gacccggcct gtcctgcggc aacacgatct ctcgggtgcc tccgtcccca
    18001 gatacccacg cgatcgggtc cgaccggctt tccccgggga actcccggaa gccgacgccg
    18061 atcgcggtcc ggcccgcgcg ggtcagcgcc accccggtcc ggccgggccc tggccggaac
    18121 agccgctgga tctcggcgac cggatcctgg gcaccgaagg cgttcgcctc gccgggccgg
    18181 gcggcgaagc ccagcgcgct cttcgcctca ctcggcggca actgccccgg gacacaggcc
    18241 gcgagcagcg acagcgcgag cactccccag agcttcctca tgggcgggaa gcctgccagc
    18301 ggaaggtcac tttccgggca gcacgatctc cgcgtagacg gcgtcgtgat cgctgccggg
    18361 cgtctccagc accttgaagt ccgcgatggc cgtccgtttg tccgccagca cgtggtcgat
    18421 cgcgaccggc ggcgcgatcc cgttcgtcca ggtgccctcc aacgccttcc ccagctcgtc
    18481 ggccgcgtcc acgtatcccc tggtcagcaa ctcacggaag agcgcgtggt ccaggctcgc
    18541 gttgaagtcg cccgccagga tccggatgtc gtgctcggcg tcagcgtacg gcaggtcctt
    18601 ggcctcggcg acccattcat gccggtccca catcggcgcc gacggatgca ccgcgacgac
    18661 ctcgacgcgg acaccgtccc cgagatccac acccgcgctg ggctgcttgt aatccgagtc
    18721 gccgctcagt ttcaacggcg tgagcgggta cttcgacacg agcccggagc cggacgccca
    18781 ctcggccgga tgcagcacgt ggtacggcag gacctggaac aacccggccc ggtcgagcgc
    18841 ggtgatcgcc tcgggggtca gctcggtcag gctcaggacg tcgacctggt gttccttcac
    18901 gtagccgacg atcctggccg gatccgcccc gccgccgagc atgttcgacg ccagcacgcg
    18961 gacgtgcttc ccgtcgagcg ccctctgctc gttcgcgaag gcgcgcggca ggaccatgga
    19021 cgcgatcgtg caggtcagca ccagtgcgac gaccgcggtc caccagcggc gcagcaccag
    19081 cgcgagaacg ccgaggacga gcgtcgcgat cccggcgtac ggggtcagtg cgagcgcggc
    19141 gatcgtgtac gtgttgccgt cgtagccgac cagccgcagc ccggtcagca ccgcgaacgg
    19201 cacgaccgcc gcgatgagga gcccgctgac cagcttccgt ccggcgccgg gacgcgccgc
    19261 cggacgaacc ggacgttctt cgatcaccat gccgtcgagt atgccgatcg agcgcgccgg
    19321 ggcagcggtc tccacaacac cttcacaacc tcctcacacg gcgtctacca gcgcttatca
    19381 gttcctgtca gccgctgcca gcgcgctgtg cgcggtctgc caggccaggg gtgcaccttt
    19441 gtccgcgggg cgagatccac aggaggaaag cgatgactca cgcgatcagg gccgagggcc
    19501 tggtcaaaca ctatggggag acgaaggcgc tcgacggggt cgatctggag gtcccggcgg
    19561 gcaaggtggt cggggtgctg gggccgaacg gcgcggggaa gacgaccgcc gtccggatcc
    19621 tggccacctt gatccggccg gaccgcggcc acgcgagcgt cttcgggtac gacgtcgtca
    19681 agaacccgat ggcggtccgg agcatgatcg ggctgaccgg gcagtacgcg tcggtcgacg
    19741 aggacctttc cggtacggag aacctcgtcc tgatcggcag gctgctggag ttctcgaggg
    19801 cggacgcgaa gaagcgcgcg gccgatctgc tggaacggtt cgagctcacc gacgccgccg
    19861 gccgcgcgat caagacctac tcgggcggga tgcggcggcg gctcgacctc gccgcgagcc
    19921 tggtcggccg tcccaaggtg ctgtacctgg acgagccgac caccgggctc gacccgcacg
    19981 cccgcaacga ggtctgggcc gtggtccgga cgctggtcgc cgacggcacg acggtgctgc
    20041 tcaccacgca gtacctggag gaggccgacc agctggccga cacgatcacc gtgttcgacc
    20101 acgggcacgt cgtggcgaac ggtcgggccg acgagctcaa gcggcggacc ggcggccaga
    20161 cgctgcaggt gcggccgtcc gcgctcgccg acctcgacgc cgtcgagcgc atcctggccg
    20221 ggctcaccgg ggtccggccg aaccgggacg acgacaccgg gctgctcacc gcacccgtcg
    20281 ccgatcccgt cctgctgtcc actttggtcc gcaagctgga cgaagcgggg atcaccgcgg
    20341 acgagctggc gctgcggctg cccagcctcg acgaggtgtt cctcgcgctg accggcaaga
    20401 agaccgacga gtccacaaag gacgctactc cggaagggag cctggtatga cgaccatcgc
    20461 cgcgcccgca ccaccacggc gcgtatcact gtcgagcagc acgcggcacg ggctttccct
    20521 cgcctggcgc ggagtgctga agatccgcaa gaacccggag cagctggccg acgtcacgct
    20581 cgcgccgatc atcttcctgg tcatgttcgt ctacctgttc ggtggcgcga tcatgggcag
    20641 caccgagagc tacctccaga tgatcgtgcc cggcatcatg gtgttca
//
