LOCUS       NZ_LIWC01000001        21131 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Amycolatopsis sp. CB00013 scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_LIWC01000001
VERSION     NZ_LIWC01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Amycolatopsis sp. CB00013
  ORGANISM  Amycolatopsis sp. CB00013
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 2203332)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2203332)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2014
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905755.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:05:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,488
            CDSs (total)                      :: 8,430
            Genes (coding)                    :: 8,383
            CDSs (with protein)               :: 8,383
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 17 of 47
            Pseudo Genes (incomplete)         :: 38 of 47
            Pseudo Genes (internal stop)      :: 1 of 47
            Pseudo Genes (multiple problems)  :: 9 of 47
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:01:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1113834
            Orig. end                         :: 1134965
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIWC01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21131
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21131
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21131
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11131](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11131)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(277..960)
                     /locus_tag="AMK34_RS04960"
                     /old_locus_tag="AMK34_04920"
     CDS             complement(277..960)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334387.1"
                     /locus_tag="AMK34_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04920"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_073844576.1"
                     /transl_table=11
                     /translation="MDERPITTAQRNFRRVAGELESMGTQDRFTYIFRSRLWSSSSASG
                     PGSESVQTRELSDQLPLLLDRFGVRTLLDLPCGDYGWLSQVDLDLDHYIGADIVPDLIE
                     LNAERFRGDPVHEFQVLDLTADPLPKADLVLCRDCLVHLSFADIERALRNLRRSGSRYL
                     LTTTFTELGTNNDIVTGDWRPLNLCREPFGFPEPLAVLVEGCTEEGGAYADKSLGLWEI
                     SAIVD"
     misc_feature    1022..1033
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(1065..1076)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(1103..1309)
                     /locus_tag="AMK34_RS42485"
     CDS             complement(1103..1309)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK34_RS42485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143202335.1"
                     /transl_table=11
                     /translation="MTTKIFPCVRAFFARCEMLIATAGYGRTSVKLAEIRAVMLTLGSL
                     VQALGRPWPTRSAYQQRVTGLIG"
     gene            1624..2025
                     /locus_tag="AMK34_RS04965"
                     /old_locus_tag="AMK34_04925"
     CDS             1624..2025
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK34_RS04965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK34_04925"
                     /product="hypothetical protein"
                     /protein_id="WP_228694976.1"
                     /transl_table=11
                     /translation="MTIQPDNAKTPDNGPPQRVKVVIEHVEKPARRVATSAEMIRAARP
                     LLRTPGRHRKVQSRDSWLCLAMAVLAGWAPTLRMCLLLTVGGAIVVGVVEISTPKVGVS
                     AGTSIGLLTLFGAWIVKSRQGKSRREPSL"
     misc_feature    complement(2071..2085)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.44"
                     /tool="antismash"
     gene            2149..3603
                     /locus_tag="AMK34_RS04970"
                     /old_locus_tag="AMK34_04930"
     CDS             2149..3603
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101037.1"
                     /locus_tag="AMK34_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04930"
                     /product="trypsin-like serine protease"
                     /protein_id="WP_241832685.1"
                     /transl_table=11
                     /translation="MRRARRLGALVVSVLAAATALGGSASAETVQSFHTSLDPASVRES
                     VRYLVENYRVSEQEALRRLELQTDGGKLDELLRRDRGAEYGGMWLDQDRGQLVVAMTKP
                     AAAEPYLRAMPSRSAVRTQQVQHSLQQLTAAKERVAAKVGAGPDAVYLPSVSESENRVV
                     LWERDWVARAKAAVATETNTAQRATAEESGMVVSRVLKNPNALATPNVDLGFCHPLYCT
                     NYGPMRGGLRLDMKRDDGTWGGCTSGFNLRSTGGGFPGKGWVLTAGHCMRTKTNNTPTQ
                     HNGNDVLQQHGIEKSSYPYDYAALPYVNDAASTKWLEGQTGRNRVLKYCRNGGMDSNGD
                     TPCGAQATSVDEYITGARKLAEIKAGYVVCASGTASSKVNYPDSVDSGAGAGYLVGTRC
                     GRVLSTDVGINTDLCARPGDSGGPLFSQADHAALGILVGNQQSRSGPCQAGELNNYAPI
                     ETITTDLSERIASQGSTFAVITTPNG"
     gene            complement(3661..4092)
                     /locus_tag="AMK34_RS04975"
                     /old_locus_tag="AMK34_04935"
     CDS             complement(3661..4092)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334391.1"
                     /locus_tag="AMK34_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04935"
                     /product="hypothetical protein"
                     /protein_id="WP_241832686.1"
                     /transl_table=11
                     /translation="MSYEGWHTGARIGTGTGDGRMLAYQDSGVEAECVFRAGESTLFNI
                     MSTGYGSDTTERGFAVWSARPGALGAIDPGVTRLDVTDADGVVVQAEIVAHTFAVDVDL
                     GPAPRTIDEVFAPWEPPELTVRVYGEDDALRYEGPLLTR"
     gene            4430..4681
                     /locus_tag="AMK34_RS04980"
                     /old_locus_tag="AMK34_04940"
     CDS             4430..4681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032717.1"
                     /locus_tag="AMK34_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04940"
                     /product="hypothetical protein"
                     /protein_id="WP_038513300.1"
                     /transl_table=11
                     /translation="MTAQRTITDEIGEIGVWLMGEFGGRLPANVISRVLNASKRDLEGR
                     IDPEELGEMFHTLCRFRLQRILAADERITVKIPDARLS"
     gene            complement(4653..6113)
                     /locus_tag="AMK34_RS04985"
                     /old_locus_tag="AMK34_04945"
     CDS             complement(4653..6113)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334393.1"
                     /locus_tag="AMK34_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04945"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_073843255.1"
                     /sec_met_domain="Aldedh (E-value: 7.5e-153, bitscore:
                     506.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITNDRLFIGGEWTAPSDPTRLDIVSPHDRSVLGRVVQALPADVD
                     RAVAAARLAFDEGPWPRTPPEERIAVLRRLNALREARADEIAELISAENGSALWFTRAG
                     QPGVGRLAVSYLKAAEEFGWEETLTPSDPSAPFRSIVRREPIGVVAAIIPWNSPFSASM
                     AKIVPALLAGNTVVLKVSPENSLSMTLLADLLKEAGLPSGVISVLPADRETSEYLVKHP
                     GVDKIAFTGSTAAGRRIASLAGERLKRVSLELGGKSAAVILPDAVMADVIAGLKFGSLL
                     NNGEACIAQTRILAPRDRYDEAVAGLEEMMESLVVGDPADEKTFIGPMVRPDQQRRVRD
                     YIEIGIAEGARLVTGGSGIPPGLDKGNYVTPTLFADVESTMRIAQEEIFGPVLVVIPYT
                     DEDDAVRIANDSEYGLSGGVWSADEDRALAVARRMRTGTVTVNGAPIGFDGPFGGYKAS
                     GIGREYGAAGLAQYVELKTVTKGERPGS"
     gene            6191..6727
                     /locus_tag="AMK34_RS04990"
                     /old_locus_tag="AMK34_04950"
     CDS             6191..6727
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334394.1"
                     /locus_tag="AMK34_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04950"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073843256.1"
                     /transl_table=11
                     /translation="MRADATRNLEAVLTTGARMLAHDPSASISAIAAEAGVDRRTVYRR
                     FASREELLSAIYDSRLTAVEQVVRAARLTETAVPVALHRYVEGIIEVNRAWPVELTRMR
                     AEPSIQDRRNRLSAEVDTFLQRATDEGFLRADVPDGWSGRLLIQLLHLASREDMDPPRA
                     ADLLVETFLNGVGAR"
     misc_feature    6765..6778
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            6793..7890
                     /locus_tag="AMK34_RS04995"
                     /old_locus_tag="AMK34_04955"
     CDS             6793..7890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334395.1"
                     /locus_tag="AMK34_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04955"
                     /product="ionic transporter y4hA"
                     /protein_id="WP_073843258.1"
                     /transl_table=11
                     /translation="MAASPRRFPLSWTTVMPVLAIVVLALSWGRDLGAVPVIIVALALG
                     GTVLAAVHHAEVVAHRVGEPFGSLVLAIAVTVIEVALIVTMMSSGGPEAGTLARDTVFA
                     AVMITMNGIAGISLMVGARRYGETHFNPEGSGGALATVATLATVSLVLPTFTTSTPGPA
                     FNGTQLTFAAVASLLLYGLFVLTQTVRHRDFFLPVDSEGSVKEEEHAEPPTNKAALTSL
                     GLLLVALVAVVGLAKVESPAIEAGVSAAGFPQSFVGVVIAMLVLLPETLAATRAARRDR
                     MQTSINLAYGSAIASIGLTIPTIALASIWLDGPLLLGLGATHIVLLALTIAVSVLTVVP
                     GRATRLQGGVHLVLLASFLVLAINP"
     gene            7945..9936
                     /gene="ligA"
                     /locus_tag="AMK34_RS05000"
                     /old_locus_tag="AMK34_04960"
     CDS             7945..9936
                     /EC_number="6.5.1.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="ligA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635616.1"
                     /locus_tag="AMK34_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04960"
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="WP_073843260.1"
                     /transl_table=11
                     /translation="MNARDRIQELADQIVVLRDAYYRGSPKVADADYDAIEDELRGLIE
                     ANPELAPEPNPLDQVGAPAVLHAPIRHSRPMLSLEKATKPEQVEAFFARFPGQPVVVMP
                     KLDGLSLALVYENGRLARAVTRGDGTTGDDVTMLVRALTDGVPDKVDAPGRVEVRGEAV
                     MLRSTFAAYNKVHPDKPLINPRNAAAGTLRAKDPATVAERRLQFFAFDLSTEPDSAETD
                     LDGALRTLGFAAADMRHCEDAESAQAVITTIEQQRNDLDYDLDGAVLRLADRDAYAAAG
                     TRSSSPRGALAFKFAAEEKTTVLADVVWDVGKTGKIAPVAWLEPVFVGGTTVTRATLAN
                     QEVIKARGIKIGDTVLVRRAGDVIPFVAGVLDAAKRTGEEREIVPPSVCPSCEEPLTEQ
                     GNSRELFCTNVACPAQTVRRLIHWASRAAADIDAIGGVWIERLAEAGILEHPSDFYRLT
                     KERLLEFDRIGDISATRMIESIDASRAVGLRRALIGLAIPMASEGTAARLCRAGFGSLE
                     AVVDAGEEGLVAVEDIGPKVAASLIEHLTRLRPELERLREVGVSLDVREEDLPPVVAAG
                     APLEGKTVVVTGSISDPRSGEKVPRPTFQRLCEKAGATIASSVSANTDLLITGADVGAS
                     KLTKAEKLEVEVVDQGVIWGQLIEAGVV"
     gene            complement(10001..11131)
                     /locus_tag="AMK34_RS05005"
                     /old_locus_tag="AMK34_04965"
     CDS             complement(10001..11131)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159832.1"
                     /locus_tag="AMK34_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04965"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_073843262.1"
                     /sec_met_domain="T1TS (E-value: 9.8e-54, bitscore: 180.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQGALATLLAGPSGLGTSAARLAARLTAVPQEAPAPEEPGLDP
                     AYAYRPWGDGSAPPLYCPVTERINDPLAVEVDRRLVLWAGECGFDEDECEQIGNAGFGR
                     LVMLAHPDCEDPERLLISAKLNAAWWAADDLYADDTSLGAVPAELPPKLALAMAAMDPV
                     PSLGEFSRDLDETLRNDRVLVALGSATDFLRRSGTAAQVQRVCYSTFAMFVSWTAYAAW
                     RHSGKYPPAWEYLAARQHDSFYTSMTLIDVLGGYELTSNLYYDPRVREAAIQAGTAAVL
                     VNDVHSVTKDLEDESPPCNAVLLIADDRKCTIEEATAITVELHNDVVRDFQAAHEKLSA
                     VPSVELQRFLRGLRGWMGGGFEWHSTSPRYRTKPSV"
     gene            complement(11149..12012)
                     /locus_tag="AMK34_RS05010"
                     /old_locus_tag="AMK34_04970"
     CDS             complement(11149..12012)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032723.1"
                     /locus_tag="AMK34_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04970"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_073843264.1"
                     /transl_table=11
                     /translation="MTIARTPAPAKVLRTEYQKSVASYWNKEKDPVNLRLGDVDGLYHH
                     HYGVGEVDWSVLEGPEETRDERIIAEMHRLETAQADVLLDHLGDVKPDDHLLDAGCGRG
                     GSSIMANARFGCHVDGISISEKQVEFANHQADIRGVADRVRYHFRNMLDTGFESGSRKA
                     IWNNESTMYVDLHELFAEHARQLEFGGRYVTITGCYNDVTGGRSKAVAQIDQHYTCNIH
                     PRSEYFKAMTANDLVPISVVDLTPDTIPYWELRAKSSVATGIEGPFLDAYREGSFHYLL
                     IAADRV"
     gene            complement(12066..13454)
                     /locus_tag="AMK34_RS05015"
                     /old_locus_tag="AMK34_04975"
     CDS             complement(12066..13454)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334401.1"
                     /locus_tag="AMK34_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04975"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_038513284.1"
                     /transl_table=11
                     /translation="MTAATPEADRRLSLGPAAARNLATTTKTRPQMQSITPRWLLKMLP
                     WVEATGGTFRVNRRLTYAIGDGRVSFTNVGTEVRVVPQELAELALLRGFDDEDTLTALA
                     DRFVQHEYQPGETIVSHGAPLDEVVLVAHGKIAKVVPGEYGAEASVGSMADGDHFGDEM
                     LAGIDRNWPFTAKAVTPVIVLTLRAEDFADLNGRSEAMRRHVQDMLSHKGKPQNAKGEA
                     EIGMSSGHDGEPLLPGTFVDYEISPREYDLAVAQTALRVHTRVTDLYNGPMDQFEEQLR
                     LTISALRERQEHDLINNREFGLLHNADLKSRFQTRSGPPTPDDMDELVSRRRKTKFFLA
                     HPRAIAAFGRECTRRSLYPEGTTVDGKVVAAWRGVPLLPCDKIPITENGTSSILAMRTG
                     VEDNGVIGLHQTGLPDEYEPGLNVRFDGISDQAVASYLVSTYYSAAVLVPDALGVLENV
                     EVAR"
     gene            complement(13451..14872)
                     /locus_tag="AMK34_RS05020"
                     /old_locus_tag="AMK34_04980"
     CDS             complement(13451..14872)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159827.1"
                     /locus_tag="AMK34_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04980"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_038513282.1"
                     /transl_table=11
                     /translation="MTVTESGTSAEGVQGSENPQLSLGRAAARNLATTTKSVPQMQGIS
                     SRWLLKSLEWVQVNGGAYRVNRRLNYAVGDGRVTFSKAGTEVSVIPAELGELKPLKGYD
                     DEEVLAELARRFEQQEVAAGDVLVEFGHRADRVFLIAHGKISKTGPGHYGDETALGVVK
                     DGDYFGAQALVDDDGIWEFTAKASTACTVLTLTRQDFERVLEQSESLQAQIEQASQDSG
                     RSNDFGEAEIDISSGHDGEPLLPGTFVDYETSPREYELSVAQTVLRVHSRVSDLYNQPM
                     DQTEQQLRLTIEALRERQEHEMINNTDFGLLHNADFTQRIATRTGPPTPDDFDDLLALV
                     WKDPGFFLAHPRTIAAFSRECSKRGIYPTGTDLGGHKVPSWRGVPILPCNKIPVSQTST
                     SSVLLIRTGEKNQGVVGLRQIGLPDEYEPGLNVRFMGISEQAIISYLVSTYYSAAVLVP
                     DALAVLEAAELGREG"
     misc_feature    complement(15050..15061)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.42"
                     /tool="antismash"
     gene            15387..15998
                     /locus_tag="AMK34_RS05025"
                     /old_locus_tag="AMK34_04985"
     CDS             15387..15998
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032728.1"
                     /locus_tag="AMK34_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04985"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_038513280.1"
                     /transl_table=11
                     /translation="MTPPARWNRYWDGKSRNYDREMQFMDRKLFGDSRAWACGQATGDV
                     LEVAVGTGLNLPLYPEGVTLTGIDLSDGMLAIARGRAERLGHPVTLRRADAHDLPFDAD
                     SFDTVVCTLGLCAIPDDGKALREMARVLRPGGRLILLDHIVSSSRAVRGLQWIAEKITV
                     PMAGEHFLRRPFDKIGDLGLAVEQRERFKLGLVERLVARK"
     misc_feature    complement(16018..16032)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            16042..16473
                     /locus_tag="AMK34_RS05030"
                     /old_locus_tag="AMK34_04990"
     CDS             16042..16473
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK34_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK34_04990"
                     /product="hypothetical protein"
                     /protein_id="WP_073843266.1"
                     /transl_table=11
                     /translation="MTFPQQQSPLWQQYPVAPPKKTPNTGLIVGIAAGALVVTGGAIAV
                     TVALATGGSAPEVDPDPFSAQAGDCLSADEDAGSNGAFSSSAVRVHCSDGSANYTVIAQ
                     LSSSSGSDCNAVPGYEYGNPVVYDFTSGQSRELCVMPKG"
     gene            complement(16419..17243)
                     /locus_tag="AMK34_RS05035"
                     /old_locus_tag="AMK34_04995"
     CDS             complement(16419..17243)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334406.1"
                     /locus_tag="AMK34_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_04995"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_241832687.1"
                     /transl_table=11
                     /translation="MLVHQSALLRNNTVIVDGEEGVLLVDPGITEGEMACLANDLAESG
                     RSVVAGFATHPDWDHALWHAAFGDVPRYGTDRCAAYLRDLRSKEDWKADFAEGLPPEIA
                     GEVPFELFGLITALPAGSTRIPWDGPELRIVEHPAHAPGHAALVIEKHGVLVAGDMLSD
                     VLVPMFDDTADPLGDYLTGLRLLEEVADDVEVVVPGHGAVGGAGQTRARIDLDRAYVHA
                     VRNGRTPDDPRIGSSAEPGWEWVSDLHAGQVQRLTQPLGMTQSSRDCPEVKS"
     gene            complement(17262..17840)
                     /locus_tag="AMK34_RS05040"
                     /old_locus_tag="AMK34_05000"
     CDS             complement(17262..17840)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334407.1"
                     /locus_tag="AMK34_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_05000"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073843270.1"
                     /transl_table=11
                     /translation="MTAPTGRRERKKAATRQKIAETALRLFLERGYDAVGIREVAAEAD
                     VAVTTLFSHFASKEALVFEQDANFEQGLTRAVTERPAGDPLIPALCREVHAMVRHCTAE
                     GAAPIWRMIDGSPALREYEDAMRLRHAESLAAAIAADPESARSSTACRTIARFVLDAYS
                     IGREAADPEAAVDEIFRMIEAAWEVTAAC"
     gene            17910..18803
                     /locus_tag="AMK34_RS05045"
                     /old_locus_tag="AMK34_05005"
     CDS             17910..18803
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (14-182). E-value: 6.7e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_AMK34_RS05045_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550955.1"
                     /locus_tag="AMK34_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_05005"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_073843272.1"
                     /sec_met_domain="ADH_N (E-value: 9.6e-09, bitscore: 32.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8e-09, bitscore:
                     32.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQVIFTEFGGPEVLQLVDAEEPHAGPGQVRIAVRAAGVNPVDWR
                     IREGQVLGAHPTVLPSGVGLDAAGVVDEVGEGVDGVAIGDSVFGEGASTYAEFAVLSAW
                     AVMPDGLTFEEAAGYPSVVETALRLIREADVRPGETLLVSGASGGVGSAVLQIARERGI
                     TVIGTAGAANQGYLRDLGALATTYGEGWVDRVRRLGRVDAALDLAGSGVIAELVELTGD
                     PGKVLSIADLGAPEFGVRFSGVAGSVPDALTEAVDLISRGKLHIPVEKSYSLADAAAAH
                     ADSHAGHTRGRRVIVV"
     aSDomain        17952..18455
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK34_RS05045_PKS_ER.1"
                     /evalue="6.70E-34"
                     /label="AMK34_RS05045_PKS_ER.1"
                     /locus_tag="AMK34_RS05045"
                     /protein_end="182"
                     /protein_start="14"
                     /score="109.3"
                     /tool="antismash"
                     /translation="LQLVDAEEPHAGPGQVRIAVRAAGVNPVDWRIREGQVLGAHPTVL
                     PSGVGLDAAGVVDEVGEGVDGVAIGDSVFGEGASTYAEFAVLSAWAVMPDGLTFEEAAG
                     YPSVVETALRLIREADVRPGETLLVSGASGGVGSAVLQIARERGITVIGTAGAANQGYL
                     RDLGA"
     CDS_motif       18099..18134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK34_RS05045_0001"
                     /evalue="2.20E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="AMK34_RS05045"
                     /protein_end="75"
                     /protein_start="63"
                     /score="8.0"
                     /tool="antismash"
                     /translation="GLDAAGVVDEVG"
     CDS_motif       18321..18383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK34_RS05045_0002"
                     /evalue="4.30E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="AMK34_RS05045"
                     /protein_end="158"
                     /protein_start="137"
                     /score="16.1"
                     /tool="antismash"
                     /translation="GETLLVSGASGGVGSAVLQIA"
     CDS_motif       18618..18641
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK34_RS05045_0003"
                     /evalue="6.90E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="AMK34_RS05045"
                     /protein_end="244"
                     /protein_start="236"
                     /score="-2.5"
                     /tool="antismash"
                     /translation="FGVRFSGV"
     gene            complement(18810..19289)
                     /gene="rraA"
                     /locus_tag="AMK34_RS05050"
                     /old_locus_tag="AMK34_05010"
     CDS             complement(18810..19289)
                     /GO_function="GO:0008428 - ribonuclease inhibitor activity
                     [Evidence IEA]"
                     /GO_process="GO:0051252 - regulation of RNA metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rraA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032734.1"
                     /locus_tag="AMK34_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_05010"
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="WP_038513267.1"
                     /transl_table=11
                     /translation="MIDSFTTADLVDEHGDRLRVCDTQFRQFGGHRTFSGPIRTVSCHE
                     DNGLVKKLLATPGDGAVLVVDGGGSLHSALTGDMIAKSAVDNGWAGIVVNGAVRDSAEL
                     AGLPLGVKALGTNPRKSSKAGVGAVDVPVGFGGVTFTPGDTLYSDDDGVVILPAA"
     gene            complement(19286..19891)
                     /locus_tag="AMK34_RS05055"
                     /old_locus_tag="AMK34_05015"
     CDS             complement(19286..19891)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334410.1"
                     /locus_tag="AMK34_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_05015"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073843273.1"
                     /transl_table=11
                     /translation="MTRLTRAEQQRRTHENLLAAGRQVFLRRGFLAATVEEIAADAGYT
                     RGAVYKHFGGKEGLWLAIIEADADGHLRGLREALAQATSRDEVIAALNPVDVADKDAAK
                     WSAAAAEVLAATAQQPETATLVAAIQRRHDDEVVALLAEHTRRLRLEPALPLDQAVVML
                     GALGIGLALRQTVAPAADPAAILTHALDTLFPPYTREP"
     gene            19952..20188
                     /locus_tag="AMK34_RS05060"
                     /old_locus_tag="AMK34_05020"
     CDS             19952..20188
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK34_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK34_05020"
                     /product="hypothetical protein"
                     /protein_id="WP_038513263.1"
                     /transl_table=11
                     /translation="MDFLAPVAAFLSLPLFLAGFAWYAARARRCGVSQSLLAPIEEIWD
                     PIAHKTNIEIQIEAERSPETPSPGDPPEFSIRR"
     gene            complement(20172..20792)
                     /locus_tag="AMK34_RS05065"
                     /old_locus_tag="AMK34_05025"
     CDS             complement(20172..20792)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159796.1"
                     /locus_tag="AMK34_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK34_05025"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_073843274.1"
                     /transl_table=11
                     /translation="MKIAVVGALGMAGSRVVAEAVSRGHHVTAVFRSTPPKSPHPGVEV
                     VRGDATDVDRMSAVFAGVDAVVGATRPRPGAEDTVAATVTALLDAAAGTRVLVVGGAGP
                     LRSPSGGLVIDDPVFVPAAWRTIASASMTQLQACEAHTGDWVYLSPPAHLEPGVRTGAY
                     RRGTTTILAAADGSSRISAEDLAVAIVDELENPGQDRHFTVGY"
ORIGIN
        1 tctgacggcg aagtgggagc gagagctggg ttacgcgctg cgcaagaacc tgtggacgtt
       61 caccgagaac cggatcgccg tccggttcca gtacgaatgg cacgaccggg ccggacagtg
      121 gtggcgcagc tacggcaacg agctctggga gttcgacgag cacggcctca tgagccgccg
      181 cgaggcgagc atcaacgacg tcgccatctc cgagaccgag cgacgcatct tcggcccgcg
      241 ccctcaggag gaacacggcg aggagttccc gctccgctag tccacgatcg ccgagatctc
      301 ccagagcccc aaggacttgt cggcgtaggc gccgccctct tcggtgcacc cctcgaccag
      361 tacggccagt ggctcgggga acccgaatgg ttcccggcac aggttcagcg gccgccagtc
      421 tccggtcacg atgtcgttgt tggtgccgag ttcggtgaac gtcgtggtca gcaggtatcg
      481 ggagccgctc cgccggaggt tgcgcaacgc ccgctcgatg tcggcgaaac tgagatgtac
      541 caagcaatcc cggcacagca cgagatcggc cttcggcagc gggtcggcgg tcagatcgag
      601 cacctggaac tcgtggaccg gatcgccccg gaatcgctcc gcgttcagct cgatgagatc
      661 gggcacgatg tccgcaccga tgtagtggtc aaggtcgaga tccacctggc tgagccagcc
      721 gtagtcgcca cacgggagat cgagcagcgt ccgaaccccg aagcgatcga ggagcagagg
      781 caactgatcg ctcagctccc gcgtttggac ggactcggag ccgggcccgg aggccgacga
      841 ggaactccac agccgggagc ggaagatgta ggtgaaacga tcctgggtcc ccatgctctc
      901 cagctcgccg gcgaccctcc ggaagttgcg ctgcgccgtg gtgatcggtc gttcgtccac
      961 ttccgcatcg tagatgacct cgcgccccac cacgccactg tcacgctcgc tcgcagctca
     1021 agtacatgaa ggcccgcttc cttgcgtcta gcgcaaggaa gggggccttc atgtacttgg
     1081 ggaaggaggc cttcacggac cttcagccaa tcagaccagt cactcgctgt tggtaagccg
     1141 agcgggtcgg ccacgggcga ccaagcgcct gaacgagtga acccaacgtg agcatgactg
     1201 ctcgaatctc ggcgagcttg accgaagttc gaccgtaccc ggcagttgcg atcagcattt
     1261 cgcatcgtgc gaaaaaggcg cgcacgcagg ggaagatctt ggtcgtcacc tgcgaagaga
     1321 accgcagctg cactttcacg ccgacgccgg gaaaggcaaa ttgccgagct gccgacggcg
     1381 ctgctccatt cggcccctcc cgctactttt agtagttttc cgggtcaccc agaccgttga
     1441 gcgacgcgtg cataccgttc agcgcgacac acgctgtact actgaacggt cacagtccgc
     1501 tttcgccaag atgtcctcag ccgcaccggt caagaaccgg taacgcacgc gtggccccct
     1561 gctgtcacag gaggccacgc ggatgtccat tcgcaagctc gctagaacaa ggacaggacg
     1621 gtcgtgacca tacagcctga taacgcgaag acaccagaca acggaccgcc ccaacgggtc
     1681 aaggtcgtca tcgaacacgt cgaaaagccg gctcggcggg tcgcgacgtc cgcggagatg
     1741 atccgcgcgg cgcggccgct gctgaggacg ccgggacgcc atcgcaaagt gcagagccgc
     1801 gacagctggc tctgcctggc gatggcggtc ctcgccggct gggcgccgac cttgcggatg
     1861 tgccttctgc tgacggtcgg cggcgccata gtcgtcggcg tcgtcgagat cagcactccg
     1921 aaagtcgggg tgtcggcggg gaccagcatc ggtctcctga ctcttttcgg cgcctggatt
     1981 gtcaagtccc gacaaggtaa atcgcggcga gagccgagtc tgtaaacgaa ttccgccccg
     2041 tgcccgcctc gtcgcgggca cggggcgcgg caatgtcgga aaatctccac gcccgttcgg
     2101 tgccctccgg ttaaatgatc gcgaagtccc gacatgtgag gagatctcgt gcggagagct
     2161 agaagactgg gggccctggt cgtttcggtg ctggctgcgg ccacggcact gggcggctcg
     2221 gcgtcggccg aaaccgtgca gtcgttccac acctcgctcg accccgcttc ggtgcgggag
     2281 tcggtgcgct atctcgtcga gaactaccga gtgagcgaac aggaggcgtt gcgccgcctg
     2341 gaattgcaga ccgacggcgg caagctggac gaactgctgc gacgcgaccg cggcgccgag
     2401 tacggcggca tgtggctcga ccaggaccgg gggcagctgg tcgtcgcgat gaccaaaccc
     2461 gcggcggccg agccgtatct gagggcgatg ccctcccgtt ccgctgttcg cacgcaacag
     2521 gtccagcact cgttgcagca gctcacggcg gccaaggaac gcgtcgcggc caaggtcggc
     2581 gcgggaccgg acgcggtcta cctgccgtcg gtgagtgagt cggaaaaccg tgtcgtgctt
     2641 tgggaacgcg actgggtggc gcgggcgaag gctgccgtgg ccaccgagac gaacaccgcg
     2701 cagcgggcca cggcggagga atccggcatg gtcgtctccc gggtgctgaa gaatccgaac
     2761 gcgctggcca cgccgaacgt ggatctcggt ttctgtcatc cgctctactg cacgaactac
     2821 ggtccgatgc ggggtggtct ccggctggac atgaagcggg acgacggcac ctggggcggc
     2881 tgcaccagcg ggttcaacct gcggtccacc ggtggcggtt tccccggcaa gggctgggtg
     2941 ctcaccgccg ggcactgcat gcggacgaag accaacaaca cgccgaccca gcacaacggc
     3001 aatgacgtcc tgcagcagca cggcatcgag aagagctcgt atccgtacga ctacgcggcc
     3061 ctgccgtacg tcaacgacgc ggcgtcgacg aagtggctcg aaggccagac cggccgcaac
     3121 cgtgtgctga agtactgccg caacggaggc atggacagca acggcgacac cccgtgcggt
     3181 gcgcaggcca cctcggtcga cgagtacatc accggcgcgc gcaagctcgc cgagatcaag
     3241 gccgggtatg tcgtctgcgc ttccggcacg gcgtcgagca aggtgaacta ccccgattcc
     3301 gtcgacagcg gagcgggtgc cggctacctc gtcgggaccc gctgtggccg ggtcttgtcc
     3361 acggacgtcg gcatcaacac cgacctgtgc gctcgtccgg gtgactccgg cgggcctctg
     3421 ttcagccagg ccgaccacgc ggcactgggc atcctggtcg gcaaccagca gtcccgctcg
     3481 ggcccctgcc aggccggtga gctcaacaat tacgcgccga tcgagacgat cacgaccgat
     3541 ctcagcgagc ggatcgccag tcagggatcc accttcgcgg tgatcacgac tccgaacggc
     3601 tgatctcgcc agtaactgga ggcccccttc gtcgcggacg cggtgaaggg ggccttcgcg
     3661 tcacctggtc agcaagggac cttcgtagcg caacgcgtcg tcctcgccgt acacccggac
     3721 cgtcagctcc ggcggctccc agggtgcgaa cacctcgtcg atcgtccggg gcgccggccc
     3781 caggtccacg tccacggcga aggtgtgtgc cacgatctcg gcctggacga cgacgccgtc
     3841 cgcgtcggtc acgtccagcc gggtcacccc ggggtcgatc gctcccagcg cgcccggccg
     3901 cgcgctccac accgcgaaac cgcgctccgt ggtgtcactc ccgtatccgg tgctcatgat
     3961 gttgaacagt gtgctttctc ccgcccggaa gacgcattcc gcctcgacgc ccgagtcctg
     4021 gtaggccagc atccgcccgt ccccggtgcc ggtcccgatc cgggctccgg tgtgccaccc
     4081 ctcgtatgac acctgacccg ccgatcccga ggatcggtaa agctccgtca gggtcatcag
     4141 ttccgcgatc caccgcgcgg tttgttcatc acttgccggg gccactacgc gtgtgccctc
     4201 ctctccgact gtccacaatg gtcaccatcg aggctggcac acccggatgt cgatcacatc
     4261 ggggtttccc cggagatcgc cccgcccact gcacggttcg gtgcaaccgg cgtcggcgat
     4321 taggccgagc agagcaatct cgcgggatcc ccgtcatggg tgatccggtc gcccgtcgga
     4381 gtgtcgccgg ggcgaaccgg cgacactccg aagcagaggg gtacggctga tgaccgcgca
     4441 gcgcacgatc acggacgaga tcggcgaaat cggtgtctgg ctgatgggcg aattcggcgg
     4501 ccggttgccc gcgaacgtga tcagccgggt gctcaacgcg agcaagcgcg acctcgaagg
     4561 ccgcatcgac cccgaagagc tgggcgagat gttccatacg ctctgccggt tccggctgca
     4621 gcggatcctg gccgcggacg agcggatcac ggtcaagatc ccggacgctc gcctttcgtg
     4681 acggtcttga gctcgacgta ctgagcgagg ccggccgcgc cgtattcacg gccgatgccg
     4741 ctggccttgt agccgccgaa gggaccgtcg aagccgatcg gcgccccgtt gacggtgacc
     4801 gtcccggtgc gcatccgtcg tgcgacggcg agcgcgcggt cctcgtcggc cgaccagaca
     4861 ccgccggaga gcccgtactc ggagtcgttg gcgatgcgga ccgcgtcgtc ctcgtcggta
     4921 taggggatga cgacgagcac gggcccgaag atctcctcct gggcgatgcg catcgtgctc
     4981 tccacgtcgg cgaacaacgt cggcgtgacg tagttgccct tgtccagacc tggcgggatt
     5041 ccggagcctc cggtgaccag gcgcgcgccc tcggcgattc cgatctcgat gtagtcgcgc
     5101 acccgccgct gctggtccgg ccgcaccatc gggccgatga aggtcttctc gtcggccggg
     5161 tcgccgacca cgagcgattc catcatctcc tcgagcccgg cgacggcctc gtcgtaccga
     5221 tcgcgcggcg cgaggatccg tgtctgcgcg atgcaggctt cgccgttgtt gagcagtgat
     5281 ccgaacttca gcccggcgat cacgtccgcc atgaccgcgt cgggcaggat caccgccgcg
     5341 gacttcccgc ccagctccag gctgacccgc ttcagccgct cccccgccag cgacgcgatc
     5401 cggcggccgg cggcggtcga accggtgaac gcgatcttgt cgacgccggg gtgcttcacc
     5461 aggtattcgc tggtctcccg atccgcgggc agcacgctga tcactccgga cggcagccct
     5521 gcctccttga gcaggtccgc gagcagggtc atgctgagcg agttctccgg cgagaccttg
     5581 aggacgacgg tgttccccgc cagcagcgcc gggacgatct tggccatcga cgccgagaac
     5641 ggcgagttcc acgggatgat cgcggcgacc acgccgatcg gctcccgtcg cacgatcgaa
     5701 cggaacggcg cggacgggtc cgagggcgtg agcgtctcct cccacccgaa ttcctccgcc
     5761 gccttcaggt acgagacggc gagacgtccc actccgggct gtccggccct cgtgaaccag
     5821 agagcggaac cgttctcggc cgagatgagc tcggcgatct cgtccgctcg ggcctctctc
     5881 agcgcgttca ggcgccggag caccgcgatc cgctcctccg gcggcgtccg tggccacgga
     5941 ccttcgtcga aggcgagccg ggccgcggcg acggcgcggt cgacgtcggc cggaagagct
     6001 tggacgacgc gtccgagaac cgaccggtca tgcggggaca cgatgtccag ccgcgtcgga
     6061 tcgctcggtg ccgtccactc gcctccgatg aagagcctgt cgttcgtgat catcgttccg
     6121 cctctctaac tgtcacagtg aagtagcact tatgacggtt aacgacacag cagcgtgata
     6181 cattcccgga atgagagccg acgctacgcg caatctcgaa gccgtcctga ccaccggcgc
     6241 gcgcatgctc gctcacgacc cgtcggccag catcagcgcg atcgccgccg aagccggtgt
     6301 cgacaggcgc accgtctatc ggcgcttcgc ctcccgcgag gaactcctgt ccgccatcta
     6361 cgactcgcgg ctgaccgcgg tcgagcaggt cgtccgcgcc gcccggctca ccgagacggc
     6421 ggtccccgtg gccttgcatc ggtacgtcga aggcatcatc gaggtcaacc gcgcctggcc
     6481 ggtcgagctg acccggatgc gcgccgaacc ctccatccag gaccgccgga accggctctc
     6541 cgccgaggtg gacacgttcc tccagcgggc caccgacgaa ggatttctcc gcgcggacgt
     6601 cccggacggc tggtccggcc ggttgctgat ccagctcctc catctcgctt cgcgggagga
     6661 catggacccc ccgcgcgccg ccgatctgct cgtcgagacc ttcctgaacg gggtcggcgc
     6721 tcgctaagaa cttcgtcacc cctcgaccca catggagcgg cgacgtcacg cagagtgtgc
     6781 gaaggtggcg gcatggccgc ttccccaagg cgattccccc tgtcctggac caccgtcatg
     6841 ccggtcctcg ccatagtcgt gctggcgttg agctggggcc gcgacctggg cgcggtgccg
     6901 gtgatcatcg tcgcgctcgc gctcggcggg acggtgctgg ccgcggtgca ccacgccgaa
     6961 gtggtggcgc atcgcgtcgg ggagcctttc ggctcgctgg tgctggcgat cgcggtcacg
     7021 gtcatcgaag tcgcgctgat cgtgacgatg atgtcctccg gcggccccga ggccgggacg
     7081 ctggcccgcg acacggtgtt cgcggcggtg atgatcacca tgaacggcat cgccggcatt
     7141 tcgctcatgg tcggcgcccg tcggtacggc gagacgcact tcaaccccga aggcagcggc
     7201 ggcgcgctcg ccacggtggc gacgctggcc accgtcagtc tcgtgctgcc gaccttcacc
     7261 accagcaccc cggggccggc gttcaacggc acgcagctca ccttcgccgc cgtcgcctcg
     7321 ctgctgctct acggcctctt cgtgctcaca cagaccgtgc gccaccgcga cttcttcctg
     7381 ccggtcgaca gcgagggttc ggtcaaggaa gaggaacacg ccgagccgcc gaccaacaag
     7441 gccgcgctca ccagcctcgg cctgctgctc gtcgcgctgg tcgccgtcgt cggcctggcg
     7501 aaggtcgaat cccccgccat cgaagcgggg gtcagcgcgg cgggcttccc gcagtcgttc
     7561 gtcggcgtcg tgatcgccat gctggtgctg ctgccggaaa cgctggccgc taccagggcc
     7621 gcgcggcgcg atcggatgca gaccagcatc aacctcgcct acggttcggc gatcgcgagc
     7681 atcgggctca ccatcccgac catcgcgctg gcgtcgatct ggctggacgg gcccctcctg
     7741 ctgggcctcg gcgcgacaca tatcgtgctg ctggcgctga cgatcgcggt cagcgtgctc
     7801 accgtcgtcc ccggccgcgc gacccggctg cagggcggcg tgcacctggt cctgctggcc
     7861 tcgttcctgg tgctcgccat caacccgtga cacgagtcct cttcggaccg ggttctgtcg
     7921 ggggtcccgg gtaatctcag ccccgtgaac gctcgggacc gcatccaaga actcgccgat
     7981 cagatcgtcg tccttcgcga cgcctactac cggggctcgc cgaaggtggc cgacgccgac
     8041 tacgacgcga tcgaagacga attgcgcggg ctcatcgagg cgaatcccga gctcgccccg
     8101 gagccgaacc cgctcgacca ggtcggcgcg cccgccgtcc tgcacgcgcc catccgccac
     8161 tcacggccga tgttgtcgct ggagaaggcg accaaaccgg agcaggtcga ggcgttcttc
     8221 gcccggttcc ccgggcagcc ggtggtcgtc atgccgaagc tcgacggact gtcgctcgcc
     8281 ctcgtctacg agaacggccg cctcgccagg gcggtcaccc gcggcgacgg gaccacgggc
     8341 gacgacgtga ccatgctggt ccgggcgctg accgacggcg tcccggacaa ggtcgacgcc
     8401 cccggccggg tcgaggtccg cggcgaggcc gtcatgctgc gttccacttt tgccgcctac
     8461 aacaaggtcc acccggacaa gccgctgatc aacccgcgca acgccgccgc cggcaccctg
     8521 cgcgcgaagg atccggccac cgtcgccgaa cggcgtctac agttcttcgc gttcgacctc
     8581 tccacggagc ccgacagcgc ggaaaccgat ctcgacggcg cgctgcggac gctcgggttc
     8641 gccgccgccg acatgcggca ctgcgaagac gccgagtcgg cgcaggccgt catcacgacc
     8701 atcgagcagc agcgcaacga tctcgactac gacctcgacg gtgcggtgct gcgcctggcg
     8761 gatcgcgacg cgtacgccgc cgccggaacg cggtccagtt caccgcgcgg ggcgctggcc
     8821 ttcaagttcg ccgccgagga gaagaccacc gtgctcgccg atgtcgtctg ggacgtcggc
     8881 aagaccggca agatcgcgcc cgtcgcgtgg ctggagccgg tgttcgtcgg cgggaccacc
     8941 gtcacgcggg cgacgttggc caaccaggag gtcatcaagg cccgcgggat caagatcggc
     9001 gacaccgtgc tggtgcggcg tgccggcgac gtgatcccgt tcgtggccgg tgtcctcgac
     9061 gccgccaagc ggaccggcga ggagcgggag atcgtgccgc cgtcggtgtg cccgtcgtgt
     9121 gaagagccgc tgaccgaaca gggcaacagc cgggaactgt tctgcaccaa cgtcgcctgt
     9181 cccgcccaga ccgtccggcg gctgatccac tgggcgtcgc gcgcggccgc cgacatcgac
     9241 gcgatcggcg gcgtctggat cgagcggctc gccgaggccg ggattctcga acacccgtcg
     9301 gacttctacc ggctcaccaa ggaaaggctg ctggagttcg atcgcatcgg cgacatctcc
     9361 gccacccgca tgatcgagtc gatcgacgcg agccgggccg tcggcctgcg ccgcgcgctg
     9421 atcggtctcg cgatcccgat ggcctccgaa ggcaccgccg cgcggctgtg ccgggccggg
     9481 ttcggttcgc tggaagccgt cgtggacgcg ggcgaagagg ggctcgtagc cgtcgaggac
     9541 atcggtccga aggtcgccgc gtccctgatc gagcacctca cccgcctccg tcccgagctc
     9601 gagcggctgc gcgaagtcgg agtctcgctg gacgtacgtg aagaagacct cccgccggtc
     9661 gtcgcggcag gcgctccgct ggaaggcaag acggtcgtgg tcaccggatc gatcagcgac
     9721 ccgcgctccg gcgagaaggt gccgcgcccg accttccagc ggctgtgcga aaaggcgggc
     9781 gcgacgatcg cgtcgtcggt ctcggcgaac acggacctgc tcatcaccgg cgcggacgtc
     9841 ggcgcgagca agctcaccaa ggccgaaaag ctcgaagtcg aggtcgtgga ccagggcgtg
     9901 atctggggcc agctgatcga ggccggtgtc gtctgacctc ctcccgcgtt tagtcctctg
     9961 aatgcggaag ttcgtgtcgc gaaccaccgc atccagagga ctaaacgctg ggcttcgtcc
    10021 ggtagcgcgg gctcgtcgag tgccattcga aaccgccgcc catccagccc cgcaatccgc
    10081 gcaggaaccg ttgcagctcc acggaaggaa ccgcgctcag cttttcgtgg gcggcctgga
    10141 agtcacggac gacgtcgttg tgcagctcga cggtgatcgc cgtggcctct tcgatcgtgc
    10201 atttccggtc gtcggcgatc agcaggaccg cgttgcaggg cggcgattcg tcctccagat
    10261 ccttggtgac ggagtgcacg tcgttgacga gcactgccgc cgtgcccgct tggatcgccg
    10321 cctcgcggac ccgagggtcg tagtagaggt tcgacgtcag ttcgtacccg ccgaggacgt
    10381 cgatcaacgt catcgaggtg tagaagctgt cgtgctgcct ggcggcgaga tactcccacg
    10441 cgggcgggta tttcccgctg tggcgccacg ccgcgtaggc cgtccagctc acgaacatcg
    10501 cgaaggtcga gtagcagaca cgctggacct gcgcggccgt cccggatcgc cgcaggaaat
    10561 ccgtcgccga gcccagtgcc accaggaccc ggtcgtttcg cagcgtttcg tcgaggtctc
    10621 ggctgaattc gcccagcgac ggcaccgggt ccatcgcggc catcgccagc gcgagcttcg
    10681 gcggcagctc ggccggcacc gcgccgagcg acgtgtcgtc ggcgtagagg tcgtcggccg
    10741 cccaccaggc ggcgttgagc ttcgccgaga tcaacagccg ctccggatcc tcgcagtccg
    10801 gatgggcgag catgacgagc ctgccgaagc ccgcattccc gatctgctcg cactcgtcct
    10861 cgtcgaaccc gcactccccc gcccacagca ccagccgccg gtcgacctcc acggcgagcg
    10921 ggtcgttgat ccgttcggtg acggggcaat acagcggcgg tgccgacccg tcaccccacg
    10981 gccggtacgc gtaagccggg tcgagaccgg gttcctcagg tgccggagcc tcctgaggaa
    11041 ccgcggtcag ccgggccgcc agccgggcgg cggacgtgcc cagcccgctc ggaccggcca
    11101 gcagcgtggc gagcgcaccc tgttcggtca tcgcttcgct ctccaggttc agacgcggtc
    11161 cgcggcgatg agcagatagt ggaagctgcc ttcgcggtag gcgtcgagga acggtccttc
    11221 gatcccggtc gccaccgaag acttcgcccg cagctcccag tacgggatcg tgtccggcgt
    11281 cagatccacc accgagatcg gcaccaggtc gttggccgtc atggccttga agtactcgct
    11341 gcgcggatgg atgttgcacg tgtagtgctg gtcgatctgc gcgacggcct tcgaccggcc
    11401 accggtcacg tcgttgtagc acccggtgat ggtgacgtag cggccgccga actccagctg
    11461 tcgcgcgtgc tcggcgaaca gttcgtggag gtccacgtac atggtgcttt cgttgttcca
    11521 gatcgccttg cgcgagccgc tttcgaagcc ggtgtcgagc atgttgcgga agtggtagcg
    11581 cacccggtcg gcgacgccgc ggatatccgc ctggtgattg gcgaactcga cctgtttctc
    11641 cgagatcgag atcccgtcga cgtggcagcc gaacctcgcg ttggccatga tgctggaccc
    11701 gccgcggccg cagccggcgt cgaggaggtg gtcgtcaggt ttgacgtcgc cgaggtgatc
    11761 gagcaggacg tcggcctgcg ccgtctcgag gcgatgcatt tcggcgatga tccgctcgtc
    11821 gcgggtctct tcggggcctt ccagcaccga ccagtcgacc tcgccgaccc cgtagtggtg
    11881 gtgatagagc ccgtccacat cgcccagacg caggttgacc gggtccttct ccttgttcca
    11941 gtacgacgcc accgacttct gatactcggt gcgcagaacc ttggcgggag cgggagtacg
    12001 ggcgatggtc acgtgcgtgg tcctttctgg agcgttgttg ttcgttgtcg tcgcggggcg
    12061 aggggtcacc gcgcgacctc gacgttctcc agcacaccga gcgcgtcggg cacgagcacg
    12121 gcggcggagt agtaggtgct gaccaggtag ctggcgaccg cctgatccga gatgccgtcg
    12181 aaccgcacgt tcagtcccgg ctcgtactcg tcgggcaggc cggtctggtg cagcccgatc
    12241 acgccgttgt cctccacacc ggtccgcatg gcgaggatcg atgacgtgcc gttctcggtg
    12301 atcgggatct tgtcgcaggg caggagcggc accccgcgcc acgcggcgac caccttgccg
    12361 tcgacggtgg tgccctccgg atacaggctg cggcgcgtgc attccctccc gaacgcggcg
    12421 atcgcgcgcg gatgggcgag gaagaacttc gtcttgcggc ggcggctgac gagttcgtcc
    12481 atgtcgtcgg gtgtcggcgg accggaccgg gtctggaacc gcgacttgag atcggcgttg
    12541 tgcagcaacc cgaactcacg attgttgatc aggtcgtgct cctgccgctc acgcagcgcc
    12601 gaaatggtca gccggagttg ctcttcgaac tggtccatcg gcccgttgta gagatcggtc
    12661 acccgcgtgt gcacccggag cgccgtctgc gcgacggcca ggtcgtactc gcgcggcgag
    12721 atctcgtagt cgacgaacgt acccggcagc aacggctcac cgtcgtgtcc ggacgacatc
    12781 ccgatctcgg cctcgccctt ggcgttctgc ggctttccct tgtgcgacag catgtcctgc
    12841 acatggcggc gcatcgcctc cgaccggccg ttgaggtcgg cgaagtcttc ggcgcgcagg
    12901 gtcagcacga tcaccggggt gacggccttg gcggtgaacg gccagttccg gtcgataccg
    12961 gcgagcatct cgtcgccgaa atggtcgcca tcggccatgc tgccgacgga ggcttcggca
    13021 ccgtactcac ccggcaccac cttggcgatc ttgccgtgcg cgaccagcac gacctcgtcg
    13081 agcggagcac cgtggctgac gatcgtctcg ccgggctggt actcgtgctg cacgaaccgg
    13141 tcggcgagcg cggtgagcgt gtcctcgtcg tcgaaacccc gcagcagagc caattccgcg
    13201 agttcctgcg ggacgacccg gacctccgtg ccgacgttgg tgaagctcac ccgtccgtcg
    13261 ccgatcgcgt aggtcaaccg ccggttgacc cggaaggtac caccggtcgc ctcgacccag
    13321 ggcagcatct tcagcagcca gcgcggcgtg atgctctgca tctgcggccg cgtcttggtg
    13381 gtcgtcgcca ggttccgcgc ggcggctggg ccgagactga gccgccggtc ggcctccggc
    13441 gtcgcggcgg tcatccttcg cggccgagtt cggcggcttc gaggacggcc agcgcgtccg
    13501 gtacgagcac ggcggcggag tagtaggtgc tgaccaggta ggagatgatc gcctgctccg
    13561 agatacccat gaaccgaacg ttgagccctg gctcgtattc gtccggcagg ccgatctgac
    13621 gcaggccgac gacgccctgg ttcttctccc cggtgcggat cagcagcacg gaactggtgc
    13681 tggtctggct caccgggatc ttgttgcacg gcaggatcgg gacgccacgc cacgacggca
    13741 ccttgtgccc gccgaggtcg gtgccggtcg ggtagatgcc gcgtttgctg cactcacggc
    13801 tgaacgcggc gatcgtgcgc ggatgcgcga ggaagaagcc ggggtccttc cacaccaggg
    13861 cgagcaggtc gtcgaagtcg tccggcgtcg gcgggccggt gcgcgtcgcg atccgctggg
    13921 tgaagtcggc gttgtggagc aggccgaagt cggtgttgtt gatcatttcg tgctcttgcc
    13981 gctcacgcag cgcttcgatg gtcaggcgca actgctgttc ggtctggtcc atcggctggt
    14041 tgtagagatc ggacacccgg ctgtggaccc ggagcacggt ctgggcgacg ctcagttcgt
    14101 attcgcgcgg cgaggtctcg tagtcgacga acgtacccgg cagcagcggc tcaccgtcgt
    14161 gtccggacga gatgtcgatc tcggcctcgc cgaagtcgtt ggagcgtccg gagtcctgcg
    14221 acgcctgctc gatctgcgcc tgcagcgatt cggactgttc gaggacgcgc tcgaagtcct
    14281 ggcgggtcag ggtgagcacg gtgcaggcgg tggacgcctt ggcggtgaac tcccagatgc
    14341 cgtcgtcgtc cacgagggcc tgcgcgccga agtagtcgcc gtccttgacg acgccgagcg
    14401 cggtctcgtc accgtagtga ccggggccgg tcttgctgat cttgccgtgc gcgatgagga
    14461 acacccgatc ggcgcggtgc ccgaattcga cgagtacgtc gccggccgcc acttcctgct
    14521 gttcgaagcg gcgcgcgagt tcggcgagga cctcttcgtc gtcgtatccc ttgagcggtt
    14581 tcagttcacc gagttccgcc gggatcacgc tgacctcggt gcccgccttc gagaaggtca
    14641 cccgcccgtc gccgaccgcg taattgagcc gccggttgac ccggtaggca ccgccgttca
    14701 cctgaaccca ttcgagggac ttcagcagcc accgggaaga aattccctgc atctgcggaa
    14761 cggatttggt cgtcgtcgcc aggtttcgcg cggcggcgcg acccaaactc agctgcgggt
    14821 tttccgaccc ctggacacct tcggcggaag tgcccgattc ggtcacggtc acagcaaggt
    14881 ccacccttcg atagtcgtgt gaacaaacaa gatccacaaa tcgcggcgtg ccggtcatgc
    14941 cccgaagtgc ggccccgcag gatcaacata gcaaggggtt tttcccacac aagcgcactt
    15001 tcaggtaata cgacaaggcc acccgaatgc cgattttccc attgtgcagg aaagcttttg
    15061 ccagcgtcac tcggcgcttt atggccgcca cgcaatcggg ccagtaattg ttctgaggtg
    15121 tcacgcgggg ccgcgccgaa actccccgcc gtgcccgcgg cacggccgtt tgagtggccc
    15181 caccggactc tttcgggtcg cctccgcatc gtcgttcgcc actggcttga cagacagcga
    15241 cgaaacagag ggttgcgtcg ggacactccg tcgggtcatg ctcagccgtt gctgacatat
    15301 cagcgatggc tgtactgtcc cgcgcgtgcc gacccgaatc ggtgccgaac cctggtctcc
    15361 ctcctcgatg gagtgaaagg agccccatga ctccgcccgc acggtggaac cggtactggg
    15421 acggcaaatc ccgcaactat gaccgggaaa tgcagttcat ggaccggaag ctcttcggtg
    15481 attcgcgggc gtgggcctgc ggacaggcca ccggcgacgt cctcgaagtc gccgtcggga
    15541 ccggcctgaa cctgccgctc tatcccgaag gggtcacgct caccggcatc gacctcagcg
    15601 acgggatgct cgccatcgcc cgcggccgcg ccgaacgcct cggccatccg gtgacgctac
    15661 ggcgcgccga cgcgcacgac ctgcctttcg acgcagattc gttcgacacc gtggtctgca
    15721 ccctcggact ctgcgccatc cccgacgacg gcaaggcgtt gcgggagatg gcccgggtgc
    15781 tccggcccgg cggcaggctc atcctgctcg accacatcgt gagttcgtcc cgcgcggtcc
    15841 gcggtctgca atggatcgcc gagaagatca ccgtgccgat ggcgggcgag cacttcctcc
    15901 ggcggccgtt cgacaagatc ggcgatctcg gcctggccgt cgaacagcgg gagcggttca
    15961 aactcgggct ggtggaacgg ctcgtcgccc gcaaatgagc cgtgtcatcc gaatttcatc
    16021 gacgcggacg atcctgagga cgtgaccttc cctcagcagc agtcgcccct ctggcagcag
    16081 taccccgtcg caccgccgaa gaagacgccg aacaccgggc tgatcgtcgg catcgccgcc
    16141 ggggcgctcg tcgtcaccgg tggagcgatc gcggtgaccg tcgcgctcgc caccggcggc
    16201 agtgcccccg aggtcgaccc cgacccgttt tccgcacagg ccggggattg cctgtcggcc
    16261 gacgaagacg ccggctccaa cggcgcgttc agctccagcg ccgtgcgggt gcactgttcg
    16321 gacggttccg cgaactacac ggtgatcgca cagctttcga gcagttccgg ctcggactgc
    16381 aacgccgtgc ccggctacga gtacggcaac cccgtcgtct acgacttcac ttcggggcag
    16441 tcgcgcgaac tctgcgtcat gcccaagggc tgagtaaggc gctgcacttg cccggcgtgc
    16501 agatcgctca cccactccca tccgggttcg gccgacgagc cgatccgcgg gtcgtcggga
    16561 gtgcggccgt ttcgcacggc gtggacatac gcccggtcca ggtcgatccg tgcgcgcgtc
    16621 tggccggcgc caccgacggc cccgtggccg ggcacgacga cctcgacgtc gtccgccacc
    16681 tcttcgagca gccggagccc ggtcaggtag tcgccgagcg gatcggcggt gtcgtcgaac
    16741 atcggcacca ggacgtcgga aagcatgtcg ccggcgacga gaacaccgtg cttctcgatc
    16801 accagcgcgg catggccggg agcgtgagcc ggatgctcga cgatccgcag ttccgggccg
    16861 tcccaaggaa tccgcgtgct tccggcgggc agagcggtga tgaggccgaa cagctcgaac
    16921 ggcacctcac cggcgatctc cggcggcagc ccttcggcga agtcggcctt ccagtcctct
    16981 ttcgaccgaa gatcgcgcag gtaggcggcg cagcgatccg tgccgtagcg gggcacgtcg
    17041 ccgaacgcgg cgtgccagag cgcgtgatcc caatcgggat gggtcgcgaa acccgccacc
    17101 acgctccggc cggactcggc caggtcgttc gcgaggcagg ccatttcgcc ttcggtgatc
    17161 ccgggatcga cgagcagcac gccttcctcg ccatcgacga tgaccgtgtt gttgcggagc
    17221 agcgcgctct ggtggaccag cacaccgttc gcgatctggg gtcaacatgc cgcggtgacc
    17281 tcccaggctg cttcgatcat ccggaagatc tcgtccaccg cggcctcggg atcggccgcc
    17341 tccctgccga tcgagtaggc gtcgagcacg aacctcgcga tagtccggca ggcggtcgag
    17401 gaccgcgccg actccggatc ggccgcgatc gccgccgcca gcgactccgc gtggcgcagc
    17461 ctcatcgcgt cctcgtactc ccgcagagcg ggcgatccgt cgatcatgcg ccagatcggg
    17521 gcggcgccct ccgcggtgca atgccgcacc atcgcgtgca cctcacggca cagtgcggga
    17581 atgagcgggt ctccagccgg ccgttcggtg accgcccgcg taaggccctg ctcgaagttc
    17641 gcgtcctgct cgaacaccaa agcctctttc gaggcgaaat gggagaagag ggtcgtgacg
    17701 gcgacgtcgg cctccgcggc cacctcgcgg atgccgaccg cgtcgtatcc gcgctccagg
    17761 aaaagccgca aggcggtctc ggcgatcttc tgacgggtcg cggccttctt ccgctcgcga
    17821 cgtccggtcg gcgctgtcat gcggtgaagc taccagatac gaaacaacaa ccgtttcaaa
    17881 acactaaccg ttagtgctac ggtcgtcgca tgaagcaagt gatcttcacc gagttcggtg
    17941 gaccggaagt tctgcaactc gtcgacgccg aagagccgca cgcgggcccc ggccaggtac
    18001 gcatcgccgt gcgagcggcc ggagtgaacc ccgtcgactg gagaatccgc gaaggccagg
    18061 ttctcggcgc gcatccgacc gtgctgccgt ccggcgtagg cctcgacgca gccggcgtgg
    18121 tggacgaggt gggcgaaggc gtcgacgggg tcgcgatcgg cgactccgtg ttcggcgagg
    18181 gtgcgagcac ctatgccgag ttcgccgtgc tgtcggcctg ggcggtcatg cccgacgggc
    18241 tcaccttcga ggaggcggcc ggatatccgt ccgtcgtcga gaccgcacta cggctcatcc
    18301 gcgaagccga tgtgcgcccc ggcgagacac tgctggtcag cggcgcgtcc ggcggggtcg
    18361 gctcggcggt actgcagatc gctcgtgaac gcggcatcac cgtgatcggc acggcgggcg
    18421 ccgcgaacca gggctatcta cgggatctgg gcgcgctcgc cacgacctat ggcgaaggct
    18481 gggtggaccg tgtgcggcgg ctcggccggg tcgacgctgc cctcgacctg gccgggtcag
    18541 gcgtgatcgc ggaactggtc gagctgaccg gggatccggg gaaggttctc tcgatcgccg
    18601 atctcggcgc gcccgagttc ggcgtccgtt tctccggcgt ggccggaagc gtgccggacg
    18661 cgctgaccga ggccgtcgac ctcatctcac ggggcaagct gcacatcccc gtcgagaagt
    18721 cctattcgct cgccgatgcc gcggcggcac acgccgacag tcatgccggg cacacccgcg
    18781 gccgccgggt catcgtcgtc tgagcgaggt caggcggcgg gaaggatcac gacgccgtcg
    18841 tcgtcggagt agagcgtgtc gccgggagtg aaggtcactc ccccgaagcc gaccgggacg
    18901 tcgacagcgc cgacacccgc cttggagctc ttgcgcgggt tggtgccgag cgccttcacc
    18961 ccgagcggga gcccggcgag ctcggcgctg tcgcgtaccg cgccgttgac gacgatgccg
    19021 gcccagccgt tgtcgacggc ggacttcgcg atcatgtcgc cggtgagcgc gctgtgcagg
    19081 gaaccgccgc cgtcgaccac caggacggcg ccgtcacccg gagtggccag gagtttcttg
    19141 accaagccgt tgtcctcgtg acaggagacg gtgcggatcg ggccggagaa ggtccggtgc
    19201 ccgccgaact gccggaactg ggtgtcgcag acgcgcagcc ggtcgccgtg ttcgtcgacg
    19261 aggtcggcgg tggtgaagga atcgatcacg gctcccgagt gtagggcggg aagagcgtgt
    19321 ccagcgcgtg ggtgaggatg gcggcgggat ccgcggcggg cgcgaccgtc tgacgcagcg
    19381 caaggccgat gcccagggca ccgagcatca cgacggcctg atccagcggc agggcgggtt
    19441 cgagacgcag gcgacgggtg tgttcggcga gcagggcgac cacttcgtcg tcgtggcgcc
    19501 gctggatcgc cgcgaccagc gtggcggttt ccggttgctg cgccgtcgcg gcgagcacct
    19561 ccgcggccgc cgcgctccac ttcgccgcat ccttgtcagc gacgtcgacg gggttcagcg
    19621 ccgcgatcac ctcgtcgcgc gaggtggcct gagcgagtgc ttcgcgcagt cctcgcagat
    19681 ggccgtccgc atcggcttcg atgatcgcca gccacagccc ttccttgccg ccgaagtgct
    19741 tgtagacggc gccgcgggtg tacccggcgt cggcggcgat ctcctcgacc gtcgccgcga
    19801 ggaaaccgcg ccgaaggaag acctggcgtc cggcggccag caggttctca tgggtgcggc
    19861 gctgctgttc ggcccgcgtc agcctggtca tcgtctcgca ttcagtaaca gagtgtttct
    19921 ggaaacgcga cgttactgta ccgtcgtccg catggacttc ctggcaccgg tggcggcgtt
    19981 tctgagcctt cccctcttcc tggccggatt cgcgtggtac gccgcgcggg cccggcgttg
    20041 cggtgtcagc cagtccttgc tcgcgccgat cgaggagatc tgggatccga tcgcgcacaa
    20101 gacgaacatc gagatccaga tcgaggccga gcggagtccg gagacgccct cccccggcga
    20161 tccacccgag ttcagtatcc gacggtgaaa tggcggtcct gtcccggatt ctcgagttcg
    20221 tcgacgatgg cgacggcgag atcctccgcc gaaatccggg acgacccgtc cgccgcggcg
    20281 aggatggtcg tcgtccctcg ccggtaggcc ccggtccgga cgccgggctc gaggtgcgcg
    20341 ggtgggctga ggtagaccca gtcgcctgtg tgcgcttcgc aggcttggag ctgcgtcatg
    20401 ctggccgagg cgatggtccg ccacgccgcc gggacgaaca ccggatcgtc gatcacgagc
    20461 ccgcccgacg gcgagcgcag cggccccgcg ccgccgacga ccaggacacg ggtaccggcc
    20521 gccgcgtcga gcagcgccgt gaccgtggcg gcgacggtgt cttccgcgcc gggccggggt
    20581 ctcgtcgcgc ccacgacggc gtcgactccc gcgaagacgg cgctcatccg atcgacgtcg
    20641 gtggcgtcac cgcgcacgac ctcgacaccc ggatgcggcg atttcggcgg tgtactgcgg
    20701 aaaacggcgg tgacgtggtg tccacgggaa acggcttcgg cgacgacgcg ggaacccgcc
    20761 atccccaacg ctccgacgac ggcgatcttc atcgaacggc acccttcggg gtgatctggc
    20821 cagcgacgat cgaggccagg gcgagcgcga acccggcgag ctggatcggg ccgagcgact
    20881 gaccgaggag cgcggcgccg agcagcgcgg cgaccatcgg cgagagcagg ccgagaacgg
    20941 cgaccgaggt gaccggcagc gacgtgattc cgcggaacca caggacgtag gcgagcaatc
    21001 cgccgatcag gccgagccag aggtagccga gagccgcgtc caggtcgatg gcgggcgggg
    21061 ctccttcgaa caggaaggtc accggcacca ggaacaatcc gcccgcggtg agctgccacg
    21121 aggcgaaggc c
//
