LOCUS       NZ_LIVW01000007        21077 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02115 scaffold7, whole genome shotgun sequence.
ACCESSION   NZ_LIVW01000007
VERSION     NZ_LIVW01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02115
  ORGANISM  Streptomyces sp. CB02115
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 472852)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472852)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905645.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,651
            CDSs (total)                      :: 7,572
            Genes (coding)                    :: 7,475
            CDSs (with protein)               :: 7,475
            Genes (RNA)                       :: 79
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 34 of 97
            Pseudo Genes (incomplete)         :: 79 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 23 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:09:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 82594
            Orig. end                         :: 103671
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVW01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21077
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21077
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21077
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11077](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11077
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    532..550
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.84"
                     /tool="antismash"
     misc_feature    complement(735..750)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    952..966
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(2208..2225)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            2423..2806
                     /locus_tag="AMK28_RS39255"
     CDS             2423..2806
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS39255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143203476.1"
                     /transl_table=11
                     /translation="MESYARKAGALTGVDPRFGVPALVTITEPESTFNNQRWRADTVDA
                     NARGRIVADGHPQNCSRGATLCIPTIFAAFHQEETATTPYAVVAAGCATINDVRDRYRV
                     DRAGSHSASRVQQADPKRSARGY"
     misc_feature    complement(2987..3003)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.39"
                     /tool="antismash"
     gene            3065..5662
                     /locus_tag="AMK28_RS30445"
                     /old_locus_tag="AMK28_29990"
     CDS             3065..5662
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_29990"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_143203477.1"
                     /transl_table=11
                     /translation="MTLVVFVALFAVIRAVGGQGDKWQATGWMNAVAVPAEWFMQFVEG
                     ASRLVKGGSEGASLSARLGCLLLLILLFVALRRWMLMYYAHKPGAVDVKKLVSSAPGME
                     HQLEGLSAQLRKQLSETNLYPPTALPAEAPADNFLDLLGDVDLEPKKLGTSLLRLFSRL
                     RPKIAYTVRGVLRQREQEPGFGVTVTVTSYAIRGSRTESIWSAAWEDAIQEAGYWVMAT
                     LVPVTRAGRRPPWQGWRGRDLPPELFAAYQQARELSQERKFDDALDRYYEALRLDPTNL
                     YLRTQIAGIQEQLWLHLDALETYYGAILLDGQNSAQRNARSAMRSWDPRRTLRHRYGWW
                     RSGLLEARFRYAVVLGVAERTADQWCKVDDPPCPRRAHARKEIRQALAPALAARHWRVL
                     TGLTPPGRDRPFGPDQEGIARQWLETELGEERRRYPIVREIFQLACGQEMRQLAADYPR
                     MIRLRHPFVRAHGTLTRTSLRLNRDVWAPLRLAWAHEDAERDGMGHLENPLSWPSSAET
                     LVRRTKRARGAFHEVRRCLSGGWRLWQDNYNAACVYAVAMNGTKGQSGSQERRALADLA
                     VDELEGAAHADVSGFHPVTRSWLLIEDPDLEKLRQESRFIRFERETYPHAAPDRHRPER
                     PLRPEMKAYDRQLLNGCAAVMEHTWRLRRGQLPVEPYVLGEWFAGEAELWRCVDRIAAN
                     QGRNWRDRERLLQRVREVADSRLLVKCGLPSRLPEMDDLLDDAAWDTLDGVQESIKNFE
                     ETFEKRLSELDAAVAVRPNDSANHRSPILLSAQWLAAVRQNGASPAFVKRAAAHQACSD
                     YETAWRAVRDLLDPDASATALSDALQRFHAPHGTWQVLAVMRTSGPHGLRRAG"
     gene            <5832..5960
                     /locus_tag="AMK28_RS40350"
                     /pseudo=""
     CDS             <5832..5960
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387266.1"
                     /locus_tag="AMK28_RS40350"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RVEHASARMKRYQIPRDRRQRGNGLHHAVQAVATLHDHALAA"
     gene            complement(6019..6477)
                     /locus_tag="AMK28_RS30450"
                     /old_locus_tag="AMK28_29995"
     CDS             complement(6019..6477)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512479.1"
                     /locus_tag="AMK28_RS30450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_29995"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_030589514.1"
                     /transl_table=11
                     /translation="MRLNDLDERIVHALAEDARRSYADIGAIVGLSAPAVKRRVDRLRA
                     EGAITGFTVRVDPAALGWETEGFIEIYCSRNTSPDAIKQGLARYPEIASASTVTGEADA
                     VVQVFAADMRHFEQVLERIAGEPYVERTKSVLVLSPLLRRYSAEAPPV"
     gene            complement(6615..8072)
                     /locus_tag="AMK28_RS30455"
                     /old_locus_tag="AMK28_30000"
     CDS             complement(6615..8072)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607337.1"
                     /locus_tag="AMK28_RS30455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30000"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_050359358.1"
                     /sec_met_domain="Aldedh (E-value: 5e-157, bitscore: 517.8,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFFTDLAHQYIDGEWRPGKGSWDIIDFNPFDGEKLASIPVATAE
                     EVDQAYRAAERAQQAWADTNPYTRRTVLEKALHLVEEREPEISDAIVAELGGTRLKAAF
                     ELHLAKEFLREAIQLALRPAGQILPSPTEGKENRVYRVPVGVVGVISPFNFPFLLSLKS
                     VAPALALGNAVVLKPHQNTPICGGTLLARIFEDAGLPAGLLNVVITDIAEIGDTLLEHP
                     VPQVISFTGSDKVGRHVATVCARNLKRAVLELGGNSALIVLDDADVDYAVDAAVFSRYV
                     HQGQVCMAANRILVDRAVEAEFTEKFVAKVASLTVGDPADPATQIGPLINSSQAESISK
                     LVDQTVAAGATALLHGRADGNLVSPSVLTGLAADSPVLHQEIFGPVALLVPFDGEDEAV
                     RIANDTPYGLSGAVHTGNIERGVRVGQRIHTGMIHINDGTVHDEPIVPFGGEKSSGLGR
                     LNGDSMVEAFTTQKWISIQHGRSQFPF"
     misc_feature    complement(8229..8242)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.01"
                     /tool="antismash"
     gene            complement(8237..9703)
                     /locus_tag="AMK28_RS30460"
                     /old_locus_tag="AMK28_30005"
     CDS             complement(8237..9703)
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960551.1"
                     /locus_tag="AMK28_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30005"
                     /product="GuaB1 family IMP dehydrogenase-related protein"
                     /protein_id="WP_073745188.1"
                     /transl_table=11
                     /translation="MRFLEPGTGRYTESPAVPYDLTYDDVFMVPGRSAVGSRQGVDLSS
                     PDGTGTTIPLVVANMTAIAGRRMAETIARRGGLVVIPQDIPIEVVTDVISWVKTRHLVL
                     DTPIELAPGQTVADALSLLPKRAHGAGVVVDADRRPVGVVTDHDLTGVDRFTQLSEVMS
                     KDLVLLDADIDPRDAFNKLDGANRKLAPAVDAQGRLVGILTRKAALRATLYTPATDAEG
                     KLRIAAAVGINGDVAGKAKQLLDAGADVLVVDTAHGHQESMISAVKAVRALDPQVPIVA
                     GNIVAAEGVRDLIEAGADIIKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEAKKHGKH
                     VWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQQSADGRFYKESFGMASAR
                     AVKNRTSDESAYDRARKALFEEGISTSRMFLDPTRPGVEDLVDSIIAGVRSSCTYAGAG
                     SLAEFAEKAVVGVQSAAGYAEGKPLHASWS"
     misc_feature    9703..9717
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.9"
                     /tool="antismash"
     misc_feature    9710..9719
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    9711..9724
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    complement(9712..9725)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.18"
                     /tool="antismash"
     misc_feature    9713..9726
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    9714..9727
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.7"
                     /tool="antismash"
     gene            10001..11077
                     /locus_tag="AMK28_RS30465"
                     /old_locus_tag="AMK28_30010"
     CDS             10001..11077
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960550.1"
                     /locus_tag="AMK28_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30010"
                     /product="terpene cyclase"
                     /protein_id="WP_073745190.1"
                     /sec_met_domain="T1TS (E-value: 1.6e-88, bitscore: 292.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSELPDIYCPFPQRTNPHVAHTRGHLDTWTRRTGLVHRESARKR
                     FEQADFGSFVGMVYPTADEEHLDLVADWFVWLFLVDDQLDDGHLGRSPDRVRNVVDRMR
                     AVVDGSAPEPLSGEDVPAAVTALADLWKRTMPNAAPHWRTRFAWHLVTYLTTATTWEAG
                     NRAEDVVPAEDTYIAKRRHTGAIHVCMDLIEIVAGIDAPESIHNDPRFITALEAACNHV
                     CWANDVYSFEKEQVLGEIHNLVHLVRHHRGFGEQQALDHVAERLAMETERFLTAEDELL
                     ELYPELSGMLVPYLDGMRSWMRGNLDWSRRTPRYNPADVGQYEEPEEYLEETVLGVPPA
                     RTEAAAPAPCAVEAPPAG"
     gene            complement(11148..12143)
                     /locus_tag="AMK28_RS30470"
                     /old_locus_tag="AMK28_30015"
     CDS             complement(11148..12143)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490194.1"
                     /locus_tag="AMK28_RS30470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30015"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_007453211.1"
                     /transl_table=11
                     /translation="MRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLET
                     ALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPAEEQEDAPDPENLGEVAAD
                     LLGELVAEGDVLGLAWGRSTIHMAAALDRLPPCTVVQLTGVYDAGTAERGSVEAVRRAA
                     QVSGGEAHPIYAPMLLPDPATAAALREQTGIARAFEYFDKVTVAAVSIGSWEPGISTVH
                     DMLSDAERAHYASLGVAAEMSAHLFDSDGRRVGRDLGERCITVEADRLRRIPEVVAIAG
                     GQRKAAAIGAVLRSGLVTSLVTDTAAADYLLTESPAGVRPALERADPDGE"
     gene            complement(12277..12960)
                     /gene="rpe"
                     /locus_tag="AMK28_RS30475"
                     /old_locus_tag="AMK28_30020"
     CDS             complement(12277..12960)
                     /EC_number="5.1.3.1"
                     /GO_function="GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpe"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044795.1"
                     /locus_tag="AMK28_RS30475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30020"
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="WP_050359361.1"
                     /transl_table=11
                     /translation="MAQINPSILSADFARLAEEAKAVEGADWLHVDVMDNHFVPNLTLG
                     VPIVEALSKATDTPLDCHLMIEDADRWAPQYVEAGAGSVTFHAEAAAAPVRLAREIRAK
                     GARASMALKPATPIEPYEDLLPELDMLLIMTVEPGFGGQSFLDIMLPKIRRTRELISKH
                     GLELWLQVDGGVSAATIERCAEAGADVFVAGSAVYGAQDPAAAVRELRAQADAATAVAP
                     WACGH"
     misc_feature    complement(12947..12960)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    13045..13057
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(13048..13068)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            complement(13134..14567)
                     /locus_tag="AMK28_RS30480"
                     /old_locus_tag="AMK28_30025"
     CDS             complement(13134..14567)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512473.1"
                     /locus_tag="AMK28_RS30480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30025"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_073745192.1"
                     /transl_table=11
                     /translation="MNDQPRRRPAKPHRRPQKDPVRFLAFEALRAVDERDAYANLVLPP
                     LLKKARAKGDFDSRDAALATELVYGTLRRQGTYDAIVAACIDRPLREVDPPVLDVLNMG
                     VHQLLGTRIPTHAAVSASVELARVVLGEGRAKFVNAVLRKVTAHDLDGWVEKVAPSYDE
                     DAEDHLSVVHSHPRWIVSALWDALGGGRAGIEDLLEADNERPEVTLAARPGRSTTDELA
                     AALGEDNSLPGRWSPYAVRMAEGGEPGALEAVQEGRAGVQDEGSQLVAAALAAAPVEGR
                     DTRWLDGCAGPGGKAALLAALAAGRGAALLAAEKQPHRARLVERALAGNPGPYQVITAD
                     GTRPPWLPGTFDRILMDVPCSGLGALRRRPESRWRRRAEDLEAFAPLQRGLLREALKAV
                     RVGGVVGYATCSPHLAETRVVVEDVLKGRGGEPVEAEWIDARPLMPGVPALGEGPDVQL
                     WPHLHGTDAMYLALLRRTG"
     gene            complement(14705..15637)
                     /gene="fmt"
                     /locus_tag="AMK28_RS30485"
                     /old_locus_tag="AMK28_30030"
     CDS             complement(14705..15637)
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576375.1"
                     /locus_tag="AMK28_RS30485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30030"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_050359363.1"
                     /transl_table=11
                     /translation="MKLVFAGTPEVAVPALDALIASGRHEVAAVVTRPDAPAGRGRRLV
                     ASPVAERAEEAGIEVLKPARPRDEEFLARLREIAPDCCPVVAYGALLPKVALDVPARGW
                     VNLHFSLLPAWRGAAPVQHAVMAGDEVTGASTFLIEEGLDSGPVYGVLTEEVRPTDTSG
                     DLLTRLAFAGAGLLAATMDGIEDGTLHAVPQPHDGVTLAPKITVEDAQVQWSAPALRVD
                     RVVRGCTPAPGAWTLFRGERLKLIQATPVLDRTDLAPGELSAAKNNVYVGTGSHAIELL
                     WVQPQGKKPMKGADWARGVRIVHGELLGL"
     misc_feature    complement(15622..15636)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            15971..16531
                     /locus_tag="AMK28_RS30490"
                     /old_locus_tag="AMK28_30035"
     CDS             15971..16531
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057355.1"
                     /locus_tag="AMK28_RS30490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30035"
                     /product="hypothetical protein"
                     /protein_id="WP_073745194.1"
                     /transl_table=11
                     /translation="MADHATHDAQARASLHLLVRDIERVRRQVDALRTLTAQLGNVYRP
                     RRSGPSAGFVVYGRAPAPTVRLAQELRDSVETLVTAAVDFDRSLGFSWDAVGSALGVTK
                     QAVHRRYGTRRATPQPAAETGGETTAVPRPVSVVPGLAGSSAGGPGSPVPSVPAARSMP
                     PQPSAQPVRDELRPGAFPGPRNG"
     gene            complement(16632..18776)
                     /locus_tag="AMK28_RS30495"
                     /old_locus_tag="AMK28_30040"
     CDS             complement(16632..18776)
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044799.1"
                     /locus_tag="AMK28_RS30495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30040"
                     /product="primosomal protein N'"
                     /protein_id="WP_073745196.1"
                     /transl_table=11
                     /translation="MSSENEQSAEPGAGAPEQLALIRETVRRAKVPRAKPRTWRGAALA
                     EELPVARVLVNKGVLHLDQYFDYAVPEELDADAQPGVRVRVRFGAGGRNVQGGRREGGG
                     LIDGFIVERLAESDYQGALAALASVVSPEPVLGPDLLALCRAVADRYAGSLADVLQLAV
                     PPRNGRAESRPSPDPLPPPQAPEPGTWERYGQGPAFLRALADGGAPRAVWTALPGPHWP
                     AEIAGAVAATLSSGRGALVVVPDGRAAGRVDAALTEALGNGRHALLTADSGPEKRYRQW
                     LAVRRGSVRAVVGTRAAMFAPVQDLGLVVIWDDGDSSHSDDNAPFPHVREVLELRAAQG
                     RCGFLLGGTGCTVEAAQLVESGWALPLLADRERLRRAAPLVRTVGDGELARDGAARSAR
                     LPSLAWQTVRDGLRSGPVLVQVPRRGYAPRLACERCRTPARCRHCAGPLQAPDQQDLNC
                     TWCGRAERAWHCAECGSTRLRAQIVGARRTAEELGRAFPAVPVRTSGRDHILDAVPDAP
                     ALVVSTPGAEPVADGGYAAALLLDGWAMLGRPDLRAGEEALRRWTAAGALVRGQDEGGT
                     VVIVAEPTERAVQALVRWDPAGFARRELAERAELGFPPVSRMASATGPAEALAAFLRTA
                     GLPPEAEILGPVPVPSAEPGRPRRPGDAPPGETWERALIRVVPGRGAALARALKTALAA
                     RMAKGATDPVRIRIDPPDIG"
     gene            complement(18909..20117)
                     /gene="metK"
                     /locus_tag="AMK28_RS30500"
                     /old_locus_tag="AMK28_30045"
     CDS             complement(18909..20117)
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187586.1"
                     /locus_tag="AMK28_RS30500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_30045"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_007453217.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDTILDALLREDPASRVAVETL
                     ITTGLVHVAGEVTTKAYADIPNLVRNKVLEIGYDSSKKGFDGASCGVSVSIGAQSPDIA
                     QGVDTAYEKRVEGDEDELDKQGAGDQGLMFGYACDETPELMPLPIHVAHRLSRRLSEVR
                     KNGTIPYLRPDGKTQVTIEYDGDKAVRLDTVVVSSQHASDIDLDSLLAPDIREFVVEHV
                     LAQLVEDGIKLDTEGYRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLAARCEVQVAYAIGKAEPVGLFVETFGTAAVDT
                     EKIENAIGEVFDLRPAAIIRDLDLLRPIYAQTAAYGHFGRELPDFTWERTDRVDALRAA
                     AGL"
     misc_feature    complement(20345..20358)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.51"
                     /tool="antismash"
     misc_feature    20592..20606
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.5"
                     /tool="antismash"
ORIGIN
        1 cgtcggtgcc ggtgccggag aggcaggagc ggctggggcg gctccgtcag gtgctgccgg
       61 agcggcagga gcggcaggag cggcaggagc ggcaggagcg gcaggagccg ctgctccctc
      121 agctgcggcc ggagcagcgg gagtggccgg agcagcagct ccgcccgcat ccttcttctc
      181 agcatccggc ccggccgcgt cgcccgagtc cgtctccgcg gtttcaggtg cgtcgacctt
      241 cggcgccagc gcctggatct ccccgaccca gcccactatc tgtcctccga gaatctccag
      301 ggtgccgcct tgtccgtcgc ggtggaacga ccacccgtag tcgctgctcg acttcgcctc
      361 gaacacgccg tgcgactcgg aggagctgcg ctgcaccttg ccgccgattc cgaagtaccc
      421 gacgctgccg ccgtaactcg tcgactcggc gctggtgctg ttggtgctgt cggagaccgc
      481 cttctggaag gcgtcgcccg cattccccca gttgtcggcc gtgatcttca cgttgcgcac
      541 gacaatgaac cccttgggca ccatcgggag cagtttgtcg cttccggctg gcggtatctg
      601 cccgtccacc gtgccgtcgc tgatacagcc cttcttcttg ccgacgatgt accagccgtc
      661 catgtggaag agatcaccaa gcagccaggg acgctcgatg ctggcgagga accactcgaa
      721 cttcaccgtc gccgtggaac tgacatccga gaagttggac cgggacgcgc tgtccgcgtg
      781 cgttcccgag gtgctgctgc tgtccgagtg cgaggcattg gccccgatgc tcaggagccc
      841 ggcgctgaag cccacgcccc ctgaggtggc agaggcgtag ttgtcgtagt acgagcggct
      901 gaactggttg ctcccacccg cagcggacga gttgaacgag ctggacgtgg catcaacgct
      961 gttgacgccg aagctcttgt tcgtgtggtc ccaccacgag accgggtcga tgtaggacca
     1021 aggaaccttc gccgccacgg caccggagag ccccagcgag tacccctcga agagcttgcg
     1081 cgcctgggcg atgaacgtcg cggcagcgct gcctccgatg gactgcgtcg tcgcgatggc
     1141 atcctcgatc tccttggcgc ccatggcgtg caggtcgttc cacgccctgt ccaccgcgcc
     1201 ctggaacttc gcgctgacca ccggccagac ctggccctgg gccgggtccg tcatggcggc
     1261 cgcgtgggcg ctggcgtagg cgctcaccgc gtcttcccac gccttcctgt tgtggttgta
     1321 gatctcgtac ttccgcgtgt atcccgtcat gttgccgtcg gcgtcgaaga cgaacagcgt
     1381 cttcttggcg gcgtcgatgc gcgcctggac ctcgggcgtg ggcgggggcg ccggctcggc
     1441 ctgcattccc gccagcgcgg tctggtacgc gaagctgacc ttgcggtcgg gccatgagga
     1501 ggcgatgccg ttcctggtga ccatcagcat gttgtcgaca cgctgtgagg tgttgaacgc
     1561 cgactggatc gcgtgctgga gctgggcatc gggctgtgga ggcgtggccg ccagagcggc
     1621 cgcgggagtg gtgccctcgg gtgcgggcgg agcggcgggg gcagcggggg cgaatcggct
     1681 gtcggtgctc gcgccggggg ccgacgagcc gccggcaggg gtccagggaa aggagtacat
     1741 cgaggggtcg atcggctgtc ccacgggcag gtgcatgtag accgcggtgc cggacggctt
     1801 gccgtccgga cccaccatcc tggccgtgat cgcctggtgg atctgatcga gcgcggcaag
     1861 cagagcctgc gtgacacccc cggtcacctg gagttgctgg tccgcgggca tggccttctc
     1921 ctttcgctca gaaacgtgcg agtcacttca gaaagcgcgg cagagatcgg agaagcagca
     1981 cgaaacggga gtcggacgtc atgtgaatcc ggccgggtcg acaaaggcac gaagacggac
     2041 cgcttcaggc gaccaatggt gagtacttga tgcttggtta ggactcttcc cagtattcaa
     2101 cattgggatc gagcgtgcac ctcagcgcgg atctcacgac cgctggcaac tctctccgac
     2161 gacgagaagc taaggcagga ccagaatgga gacagaagtt gacagagtat ccgcactaga
     2221 ggcctctcaa gccctgggcc caggaggcga cgcgcatggt gcggctcggc agcactcaat
     2281 tcggcaatcc ctgaccgggc tcgggcgcat cgcgggcttc gctgtggact gactgccgcg
     2341 gcggcccggc ggcagcgccc gcgcaaaagg gaaggttcag cctggcccag gtcacgtaca
     2401 acgatccgaa ggacgggccg ggatggagag ctacgcccgg aaggcaggcg ccctgacggg
     2461 cgtggatcca cgcttcggag tgccggcgtt ggtcacgatc acagagccgg aatccacttt
     2521 caacaaccag cggtggcggg ccgacacagt ggacgcgaac gcacgtggcc gcatcgtggc
     2581 cgacgggcat ccgcagaact gctcgcgcgg cgccacactg tgcattccca ccatcttcgc
     2641 cgccttccat caggaggaaa ccgccacgac gccgtacgcc gtggtagccg ctgggtgcgc
     2701 caccattaac gacgtacgtg atcgctatcg cgtggaccgg gcgggttccc attccgcatc
     2761 acgtgttcag caggccgatc cgaagaggtc tgcccgcgga tactgagggc tctcccgggg
     2821 acaggatggt tgtctcgtca attgtccggt tcgagacgcc acatgaggcc cggacggtca
     2881 gccgcgccgg ccgctgcccc gcatgcgcac cacgtgcccg tcggcttgcc gggtggcgaa
     2941 aacgtagaag acttggctgt aaaggcgagc acgaccaggg gcagccatgt tctctcgttc
     3001 cgaacaccaa tctcctgccg atgggtcttc gctacgagcg ccgcacgtga tgcgttcggc
     3061 ggcgatgaca ctcgtcgtct tcgtcgccct gttcgccgtg atccgcgctg tcggcggcca
     3121 gggagacaag tggcaggcga cgggctggat gaacgccgtc gcggtacccg ccgagtggtt
     3181 catgcagttc gtcgagggtg cctcccgcct ggtgaaggga ggcagcgagg gcgcttcgct
     3241 cagtgcccgg ctcggttgtc tgctgcttct catcttgctg ttcgtggcgc tccggcgctg
     3301 gatgctgatg tattacgccc acaagcccgg tgccgtggac gtgaagaagc tcgtttcctc
     3361 cgcaccgggc atggagcatc aactggaggg actttcggcg cagttgcgca agcagctgtc
     3421 ggaaacgaac ctctaccctc cgacggccct gcccgcggag gcgccggctg acaactttct
     3481 cgatctgctc ggtgacgtcg acctcgaacc caagaagctg ggcacgagcc tgctccgcct
     3541 cttcagccgc ctacggccca agatcgccta cacggttcga ggagtcctcc ggcaacgcga
     3601 acaggagcct ggtttcggtg tcaccgtcac tgtcacctcc tacgcgatcc ggggcagtcg
     3661 cacggaatcc atctggagcg cggcatggga ggacgcgata caggaggcgg gatactgggt
     3721 gatggcaacg ctggtgcccg tcactcgggc cggccggcgc cctccctggc agggatggcg
     3781 cggccgagac ctgccgcccg agctgttcgc cgcctaccag caggctcggg agctcagcca
     3841 ggagcggaag ttcgacgacg cactggaccg ctactacgag gcgttgcggc tcgacccgac
     3901 caacctctac ctccgcacgc agatcgccgg gatacaggag cagctctggc ttcacctgga
     3961 tgccttggag acctactacg gagccatcct tctggacgga cagaacagcg cgcagcgcaa
     4021 cgcacggtca gcaatgcgct cctgggaccc gcgccggacc ctccggcatc gctacggatg
     4081 gtggcgaagc ggcctcctgg aggcgcgatt ccgctacgcc gtcgtcctcg gggtggcgga
     4141 aaggaccgcc gaccagtggt gcaaggtcga cgatccaccg tgcccgcggc gggcacacgc
     4201 ccgaaaggag atccggcagg ctctggcccc cgctctcgcc gcacggcact ggcgtgtcct
     4261 caccggtctc acgccaccgg gccgcgacag gccgttcggg ccggaccagg aaggaatcgc
     4321 caggcagtgg ctcgagacgg agctcggcga ggagcggcgt cggtatccga tcgtccgtga
     4381 gatcttccag ctggcctgcg ggcaggagat gcgccaactc gctgcggact atccccgcat
     4441 gatccgcctc cggcacccct tcgtccgggc tcacggaaca ctcacccgga cctccctgcg
     4501 gctcaaccgg gatgtatggg cacccctgcg actggcctgg gcccacgagg acgcggagcg
     4561 tgacggcatg gggcacctgg agaacccgct gtcctggccc tcgtccgcgg agacgctcgt
     4621 gcgcaggacc aagagggccc gaggcgcctt ccacgaggtg cgccgatgcc tgtccggcgg
     4681 atggcgtctg tggcaggaca actacaacgc cgcgtgtgtg tacgcggtgg cgatgaacgg
     4741 aaccaagggg cagtcgggga gtcaggaacg cagagccctt gcggacctgg ccgtggacga
     4801 actggagggc gcggcgcacg ccgatgtgag cggctttcat ccggtgacgc ggtcgtggct
     4861 gctcatcgag gacccggatc tggagaagct gcgccaggag agccggttca tccgtttcga
     4921 gcgggagacc tatccccatg ccgcgccgga ccgtcatcgg cccgagcgac ctctgcggcc
     4981 ggagatgaag gcctacgaca ggcagttgct gaacggatgc gccgcggtca tggagcacac
     5041 gtggcgtctc aggcgcgggc agctgcccgt cgagccgtac gtcctcggcg agtggttcgc
     5101 cggcgaggcc gagctctggc ggtgcgtgga ccgcattgcc gcgaaccagg ggcgcaactg
     5161 gcgtgaccgc gagagactcc tgcagcgtgt cagggaggtc gccgacagca ggctgctggt
     5221 caagtgcggg ctgccgtcga ggctgcccga gatggacgac ctgctggacg acgcggcctg
     5281 ggacacactc gacggcgtgc aggaaagcat caagaacttc gaggagacgt tcgagaagcg
     5341 cctctcggag ttggacgctg ccgtggcggt gcggcccaac gattcggcca accaccggtc
     5401 cccgatcctg ctcagcgctc agtggctggc cgccgtgcgg cagaacggcg catcgccggc
     5461 cttcgtcaag agggccgctg cccatcaggc gtgctcggac tacgaaaccg cgtggcgggc
     5521 cgtacgcgat ctcctcgacc ccgatgcgag cgccacggcg ctctcggacg cactgcagcg
     5581 cttccacgcg ccccacggca catggcaggt gcttgctgtg atgagaacga gcgggcccca
     5641 cggcctccgg cgagccggct gacccggcgg ggccacgccg cacgccgcct ggccgccgcg
     5701 tacgcctcac tcgttgagca ggacagggtc gcccagtgga aaccctgtca ggccccgtct
     5761 caagcgtgtt gcagaaggct ggggtgcggg tgtttctcct gcatgggtgg ggtgttgcgg
     5821 gctgaggcgg ccgcgtggaa cacgcctcag cgcgcatgaa gcgctaccag atccctcgcg
     5881 accgtcgaca acgcggaaac ggcctccacc atgcggtcca ggccgtcgcc accctgcatg
     5941 accacgccct ggccgcatga tccgcacgac accagagccc ggcttcaccc gcccggcacc
     6001 ggacgtccgc aacacgcttc agacgggcgg cgcctccgcc gaataccgcc gcagcagcgg
     6061 cgagagcacc aggacggact tggtccgctc gacgtacggc tcccccgcga tccgctccag
     6121 gacctgttcg aagtggcgca tgtcggcggc gaagacctgc accaccgcgt ccgcctcccc
     6181 ggtcaccgtc gaggccgagg cgatctccgg gtagcgggcg aggccctgct tgatggcgtc
     6241 cggggaggtg ttgcggctgc agtagatctc gatgaagccc tcggtctccc agccgagcgc
     6301 cgcggggtcg acccgcacgg tgaagccggt gatcgccccc tcggcccgca gccggtcgac
     6361 gcggcgtttc acggcggggg cggagaggcc gacgatcgcg ccgatgtcgg cgtaggaacg
     6421 ccgggcgtct tcggcgaggg cgtggacgat gcgttcgtcg aggtcgttca ggcgcacgtc
     6481 gggcggttca cttctctgcg gtgggtcggc ttgcgggagg cggagcgtgc cgcctcccgc
     6541 agtagaccat gccccgccgc cgagggcgtg cccgacgcga tggccccgcc cggccgggac
     6601 cgggcgggag gcgatcagaa ggggaactgc gagcggccgt gctggatgga gatccacttc
     6661 tgggtggtga aggcctcgac catcgagtcg ccgttcagcc ggccgaggcc ggagctcttc
     6721 tcgccgccga aggggacgat cggctcgtcg tggacggtgc cgtcgttgat gtggatcatg
     6781 ccggtgtgga tgcgctgccc gacccgcacc ccgcgctcga tgttgccggt gtggacggcg
     6841 ccgctgaggc cgtacggggt gtcgttggcg atgcggacgg cctcgtcctc accgtcgaag
     6901 ggcaccagca gggcgacggg gccgaagatc tcctggtgca ggacgggcga gtcggcggcg
     6961 aggccggtca gcacggaggg gctgaccagg ttgccgtcgg cgcggccgtg caggagggcc
     7021 gtcgccccgg cggccacggt ctggtcgacg agcttggaga tggactcggc ctgcgaggag
     7081 ttgatcagcg ggccgatctg ggtggccggg tcggccgggt cgccgacggt gagcgaggcg
     7141 accttggcga cgaacttctc ggtgaactcc gcctccacgg cgcggtcgac caggatgcgg
     7201 ttggcggcca tgcagacctg gccctggtgg acgtaccggc tgaagaccgc cgcgtcgacg
     7261 gcgtagtcca catcggcgtc gtcgagcacg atcagggcgc tgttgccgcc gagttcgagg
     7321 acggcgcgct tgaggttccg ggcgcagacg gtggcgacgt ggcggccgac cttgtccgag
     7381 ccggtgaagg agatgacctg cggcacgggg tgctccagca gggtgtcgcc gatctccgcg
     7441 atgtcggtga tcacgacgtt cagcagcccg gcgggcaggc ccgcgtcctc gaagatcctg
     7501 gccagcaggg tgccgccgca gatcggggtg ttctggtgcg gcttgaggac gacggcgttg
     7561 ccgagggcca gcgcgggggc cacggacttg agggagagca ggaaggggaa gttgaacggg
     7621 ctgatcacac cgacgacccc gacgggcaca cggtagacgc ggttctcctt gccctcggtc
     7681 ggcgagggga ggatctgtcc ggcggggcgc agcgccagct ggatcgcctc gcggaggaac
     7741 tccttggcca ggtgcagttc gaaggcggcc ttcagccggg tgccgccgag ctcggcgacg
     7801 atcgcgtcgc tgatctccgg ctcgcgctcc tcgacgaggt gcagcgcctt ctccaggacg
     7861 gtccgcctgg tgtacgggtt ggtgtccgcc cacgcctgct gggcgcgctc ggcggcgcgg
     7921 taggcctggt cgacctcttc ggcggtggcg accgggatcg aggcgagctt ctccccgtcg
     7981 aacgggttga agtcgatgat gtcccaggac cccttccccg gcctccactc gccgtcgatg
     8041 tactggtggg ccaggtcagt gaagaaggac atgagatccc ttaccgcaga gaggcagcag
     8101 ctgagtgcgc ttcatattac ttactattca acagagttga agcgcatacc cgacggcctc
     8161 ccggagtccg gaaacaacgc tgccctctcc ggcacgaagt accggaaagg gcagcgttgt
     8221 tgcgtcgatt ttgggatcaa ctccagctgg cgtggagcgg cttgccctcg gcgtagccgg
     8281 cggcgctctg gacgccgacg accgccttct cggcgaattc cgccagggag ccggcgcctg
     8341 cgtaggtgca ggaggagcgg acgcccgcga tgatcgagtc gacgaggtcc tcgactcccg
     8401 ggcgcgtcgg gtcgaggaac atccgcgagg tggagatgcc ctcctcgaag agcgccttgc
     8461 gggcgcggtc gtacgcggac tcgtccgagg tgcggttctt cacggcgcgg gccgaggcca
     8521 tcccgaagga ctccttgtag aagcggccgt cggcggactg ctggaggtcg ccgggcgact
     8581 cgtacgtgcc cgcgaaccag gagccgatca tcacgttgga cgcgccggcg gcgagcgcca
     8641 tcgcgacgtc gcgcgggtgc cggacgccgc cgtccgccca gacgtgcttg ccgtgcttct
     8701 tcgcctcggc ggcgcactcc aggacggcgg agaactgcgg gcggccgacg ccggtcatca
     8761 tccgggtggt gcacatggcg ccggggccga cgccgacctt gatgatgtcc gcgcccgcct
     8821 cgatcaggtc gcgcacgccc tcggcggcga cgatgttgcc cgcgacgatc ggcacctgcg
     8881 ggtcgagggc ccgtacggcc ttcaccgcgc tgatcatgga ttcctggtgg ccgtgggccg
     8941 tgtccacgac gaggacgtcg gcgcccgcgt ccaggagctg cttggccttg ccggccacgt
     9001 cgccgttgat gccgacggcg gccgcgatgc gcagcttgcc ctcggcgtcg gtggcggggg
     9061 tgtagagcgt ggcgcgcagg gcggccttgc gggtgagtat gccgacgagg cgtccctggg
     9121 cgtcgaccgc gggggcgagc ttgcggttgg cgccgtcgag cttgttgaag gcgtcgcgcg
     9181 ggtcgatgtc cgcgtcgagc agcaccaggt ccttggacat gacctcggag agctgggtga
     9241 agcggtcgac gcccgtgagg tcgtggtcgg tgacgacgcc caccggacgg cggtcggcgt
     9301 cgacgacgac gcccgcgccg tgggcccgct tgggcagcag ggacagcgcg tcggcgacgg
     9361 tctggccggg ggccagctcg atcggggtgt cgaggacgag gtggcgcgtc ttgacccagg
     9421 agatgacgtc ggtgacgacc tcgatcggga tgtcctgggg gatgacgacg aggccgcccc
     9481 ggcgggcgat ggtttcggcc atccgccggc ccgcgatggc ggtcatgttg gcgaccacga
     9541 gcggaatggt ggtgccggtt ccgtcgggcg acgagaggtc cacgccctgc cgggagccga
     9601 ccgcggagcg gcccgggacc atgaagacat cgtcgtacgt gaggtcgtac gggaccgcgg
     9661 gggactctgt gtagcgaccg gtgcccggct caagaaaacg cataacactc attttttcat
     9721 acgaaacggt gcaggtcgtt tccccgaaga cacaacaaaa gacccccgcg ttcgtctttt
     9781 cctccgaaga ggcggtcggg ggctccgggc aagtggaacc tgccttaccc acggacccta
     9841 cccgaacagg attcaatcat tcgtgatcac catccctgga ccgggtgaca aggggtcagg
     9901 tagcttcaaa cccgcaggtc tcgggggtgt ccgaagcgtc gatcgggctc gtcggcaccc
     9961 ctgggcacac cgtttgaccg gagaggatcc cgatccgcct gtggacagcg aactgccgga
    10021 catctactgc ccgttcccgc agcggaccaa cccgcacgtg gcacacaccc gggggcatct
    10081 ggacacctgg accagacgga cgggtctggt ccaccgcgag tccgcaagga agcggttcga
    10141 gcaagccgat ttcggatcgt tcgtcggcat ggtctacccg accgccgacg aggagcacct
    10201 cgatctggtg gccgactggt tcgtctggct cttcctggtc gacgaccagc tcgacgacgg
    10261 ccacctcgga cgttcacccg accgggtgag aaacgtcgtc gaccggatgc gcgcggtggt
    10321 cgacggctcc gcccccgagc cgctgtcggg cgaggacgtc ccggccgccg tgaccgccct
    10381 ggccgacctg tggaaacgta cgatgccgaa cgccgccccg cactggcgga cccggttcgc
    10441 gtggcacctg gtcacctacc tcacgaccgc cacgacctgg gaggcgggca accgagccga
    10501 ggacgtggtg cccgcggagg acacgtacat cgccaagcgg cggcacaccg gggccatcca
    10561 cgtctgcatg gacctcatag agatcgtggc gggcatcgac gccccggagt cgatccacaa
    10621 cgacccccgc ttcatcaccg cgctggaagc cgcgtgcaac cacgtgtgct gggccaacga
    10681 cgtgtactcc ttcgagaagg agcaggtgct cggcgagatc cacaacctcg tccacctggt
    10741 ccgccaccac cggggcttcg gggagcagca ggcgctggac cacgtcgcgg agcgcctcgc
    10801 gatggagacc gagcggttcc tgaccgccga ggacgagctg ctggagctgt atccggagct
    10861 gtccgggatg ctggtgccct acctcgacgg gatgcggagc tggatgcgcg gcaacctgga
    10921 ctggtcgcgc cggacgccgc gctacaaccc cgccgacgtg ggccagtacg aggagcccga
    10981 ggagtatctg gaggagacgg tgctgggcgt gccgcccgcg cgcaccgagg ccgccgcccc
    11041 cgccccgtgc gcggtcgagg ctccgccggc cggctgacgc gggtcaggac gcaccgaggg
    11101 ccgtgcaccg gatacggtgc acggccctcg atgtgttccc gccgatgtca ctccccgtcg
    11161 gggtcggccc gctccagcgc cggacggacg cccgcggggg actcggtgag cagatagtcg
    11221 gccgcggcgg tgtccgtcac caggctggtg acgaggccgg agcgcagcac cgcgccgatc
    11281 gccgccgcct tgcgctgacc accggcgatc gcgaccacct cgggaatccg gcgcagccgg
    11341 tccgcctcca cggtgatgca gcgctcaccc aggtcacggc cgacccggcg gccgtcggag
    11401 tcgaagaggt gcgcggacat ctcggcggcg acgccgagcg aggcgtaatg ggcgcgctct
    11461 gcgtccgaga gcatgtcgtg gaccgtggag atgcccggct cccaggagcc gatggagacg
    11521 gcggcgaccg tcaccttgtc gaagtactcg aaggcccggg cgatgccggt ctgctcgcgc
    11581 agcgcggcgg ccgtcgccgg gtcgggcagc agcatcgggg cgtagatggg gtgtgcctcg
    11641 ccgccggaga cctgagccgc ccggcggacc gcctcgaccg agccgcgctc ggcggtgccc
    11701 gcgtcgtaca cgccggtcag ctggacgacc gtgcacggcg ggagccggtc gagggcggcc
    11761 gccatgtgga tggtggagcg gccccaggcc aggccgagca catcgccctc ggcgaccagc
    11821 tcgcccagga ggtcggccgc gacctcgccc aggttctccg ggtcgggggc gtcctcctgc
    11881 tcctcggccg gggactcgac gaccaccgcg tgccgcaggc cgtaacgggc ccgcagggcg
    11941 tcggagcgtt cggcgtccag ctcggccggt acccggatct cgatgcgtac gagatcgcgt
    12001 tcgagggctg tctccaggac ccgggccacc ttgaagcggc tcacgccgaa ctcctcggcg
    12061 atctggatct tggacttgcc ctccaggtag aaccggcggg ccatggccgc cgcctgcacc
    12121 aactccgcgg gtcccatccg catggctgac cgacccgccg agatgccaga caccgcgatc
    12181 tcctcactgc tgttcacacg cccgatacgc cgttcatcct gtcagatccg gcgatccttg
    12241 atcggccctg tcggaccacg ttcatctgcc cttggttcag tgtccgcacg cccagggggc
    12301 gacggccgtg gccgcgtccg cctgcgcccg cagctcccgc accgccgccg ccgggtcctg
    12361 cgcaccgtag accgcggagc ctgccacgaa gacgtcggcg ccggcctcgg cgcagcgctc
    12421 gatggtggcg gccgagaccc cgccgtcgac ctggagccac agttcgaggc cgtgcttgct
    12481 gatcagctcc cgggtgcggc ggatcttcgg cagcatgatg tccaggaagg actggcctcc
    12541 gaagcccggc tcgaccgtca tgatcagcag catgtccagc tcggggagca ggtcctcgta
    12601 cggctcgatg ggcgtcgcgg gcttgagcgc catcgaggcg cgcgccccct tcgcccggat
    12661 ctcccgcgcc aggcgcaccg gagccgccgc ggcctccgcg tggaaggtga ccgatccggc
    12721 ccccgcctcc acgtactggg gggcccagcg gtccgcgtcc tcgatcatga ggtggcagtc
    12781 cagcggggtg tccgtggcct tgctgagcgc ctcgacgatc ggcacgccga gggtcaggtt
    12841 gggcacgaag tggttgtcca tgacatcgac gtggagccag tccgcgcctt cgacggcctt
    12901 cgcctcctcg gcgagacgcg cgaaatcggc ggacaggatg ctggggttga tctgcgccat
    12961 gacccaagcc tgccacgtct cacgccggtt ccccgcctcg atgggccccg aagcctcaca
    13021 cggccatcac agttcgcaca ttctgcgcat tttgccagcg ctttactctt cttttgctgt
    13081 tcacggagtg agacggccgg ccggccctcc tccgcgcagg gccggccgga cgctcagccg
    13141 gtccggcgca gcagcgccag gtacatcgcg tcggtaccgt gcagatgcgg ccacagctgg
    13201 acgtcggggc cctcccccag ggcgggcacc ccgggcatca gcgggcgggc gtcgatccac
    13261 tccgcctcca ccggctcccc gccacggccc ttgaggacgt cctcgaccac cacgcgggtc
    13321 tccgcgagat gcggcgagca ggtcgcgtag ccgaccacgc cgccgacccg tacggccttc
    13381 aacgcctcgc gcagcaggcc gcgttggagt ggggcgaagg cttccaggtc ctcggcgcga
    13441 cgccgccagc gggactccgg acgacgccgc agcgcgccca ggccggagca gggcacgtcc
    13501 atcaggatcc ggtcgaacgt gccgggcagc cacggcgggc gggtgccgtc cgcggtgatc
    13561 acctggtacg ggccggggtt gccggcgagc gcccgctcga ccagccgggc gcggtgcggc
    13621 tgcttctcgg cggcgagcag ggcggcgccc cggccggcgg cgagggcggc gagcagcgcg
    13681 gccttgccgc cggggcccgc gcagccgtcc agccagcggg tgtcacggcc ctcgacgggt
    13741 gcggcggcca gggcggcggc gacgagctgg ctgccctcgt cctggacgcc cgcccggccc
    13801 tcctggacgg cctccagcgc tccgggctcg ccgccctcgg ccatccggac cgcgtacggg
    13861 gaccagcggc ccggcaggga gttgtcctcg cccagggccg ccgccagctc gtcggtggtg
    13921 gagcggccgg ggcgggccgc caatgtcacc tcgggccgct cgttgtcggc ttcgagaagg
    13981 tcctcgatgc ccgcccggcc gccgcccagc gcgtcccaga gggcggagac gatccagcgg
    14041 gggtgggagt gcacgacgga caggtggtcc tcggcgtcct cgtcgtacga cggggcgacc
    14101 ttctccaccc agccgtcgag gtcgtgcgcg gtgaccttgc gcagcaccgc gttgacgaac
    14161 ttcgcgcgcc cctcccccag caccacccgg gcgagctcca cactggcgga gacggccgcg
    14221 tgggtgggga tgcgggtgcc gagcagctgg tggacgccca tgttcaggac gtcgaggacc
    14281 ggcgggtcga cctcgcgcag cggccggtcg atgcaggccg ccacgatcgc gtcgtaagtg
    14341 ccctgccggc gcagcgtccc gtagaccagc tcggtcgcca gcgccgcgtc ccggctgtcg
    14401 aagtcaccct tggcgcgggc cttcttcagc agcgggggca gcacgaggtt ggcgtacgcg
    14461 tcacgctcgt cgacggcccg gagcgcctcg aaggcgagga aacggaccgg gtccttctgc
    14521 ggacgacggt ggggcttggc gggacggcga cgcggctggt cgttcacgtg aaaggtgctc
    14581 cgctgatggt gagaggggcg aaccctccca gcgtacgtcg ccgcccccgg gcgcccgaac
    14641 ggcagcccgg gccccggaac gccgcccggg cccggggacc tcccccgccg cccggggtgc
    14701 ctctctacag gccgagcagc tcgccgtgga cgatgcggac gccgcgcgcc cagtcggcgc
    14761 ccttcatcgg cttcttgccc tgcggctgga cccagagcag ctcgatcgcg tgcgacccgg
    14821 tgcccacgta cacgttgttc ttggcggcag aaagctcgcc gggggccagg tcggtgcggt
    14881 ccaggacggg cgtggcctgg atcagcttga gccgctcgcc gcggaacagg gtccaggcgc
    14941 cgggggccgg ggtgcagccg cgcaccaccc ggtcgacccg cagggcgggc gcggaccact
    15001 ggacctgggc gtcctcgacg gtgatcttcg gggccagggt gacgccgtca tggggctggg
    15061 gcacggcgtg cagcgtgccg tcctcgatgc cgtccatggt ggcggcgagc agcccggcgc
    15121 cggcgaaggc gagccgggtc agcaggtcgc cgctggtgtc ggtggggcgg acctcctcgg
    15181 tgaggacgcc gtagaccggg ccggagtcca ggccctcctc gatcaggaag gtcgacgcgc
    15241 cggtcacctc gtccccggcc atcaccgcgt gctggaccgg cgccgcgccc cgccaggcgg
    15301 gcagcaacga gaagtgcagg ttgacccagc cccgggcggg cacgtcgagg gcgaccttgg
    15361 gcagcagcgc gccgtaggcg acgaccgggc agcagtccgg ggcgatctcg cgcagccggg
    15421 cgaggaactc ctcgtcccgg ggcctggcgg gcttcagcac ctcgatcccg gcctcctccg
    15481 cgcgctcggc caccgggctc gcgacgagcc ggcggccccg cccggcgggg gcgtccggac
    15541 gggtcacgac ggcggccacc tcatggcggc cggaggcgat cagggcgtcc agtgcgggga
    15601 cggcgacttc gggggtgccg gcgaagacga gcttcatggg tggctgactg cctctcgggc
    15661 caagacgtac ggtgacgagc agcacaccag tctaggggct ctcgttcgga tcacaccggg
    15721 gcccgcgagc ccggcccgat ccgaacgaga gcccctgggg tctccgtccg ggcgtggtcc
    15781 ggcggggcca ctgcgggcga gcgccgcccg ggggggcgta cgcgcgccgc gcacgccccg
    15841 tgcatatgca catacgcccc gatagcgtga ccacataccc ggctcgggcg ttggtcaaag
    15901 gagattgacc gaagcgggcc gccccgattg cggcccgatc cctttcaacg ccggttcgag
    15961 aggcttcttc atggccgacc acgcaaccca cgacgcccaa gcgcgggcca gtctgcatct
    16021 tctggtgcgg gacatcgagc gggtccggcg gcaggtggac gcgctgcgca ccctcaccgc
    16081 ccagctgggc aacgtctacc gtccgcgccg ctccggcccc tccgcgggct tcgtcgtcta
    16141 cggcagggcc ccggccccca ccgtccgcct cgcgcaggaa ctgcgggaca gcgtcgagac
    16201 cctggtcacg gccgcggtgg acttcgaccg ctcgctgggc ttctcctggg acgcggtggg
    16261 ctccgccctc ggcgtcacca agcaggccgt gcaccgccgt tacggaacgc gccgggccac
    16321 gccgcagccc gcggccgaga cgggcggcga gaccacggcc gtgccgcgcc cggtctccgt
    16381 agtaccgggg ctggccggat cctccgccgg ggggcccggc tccccggtgc cctcggtccc
    16441 ggcggcccgc tcgatgccgc cgcagccgtc ggcccagccg gtccgcgacg agctgcgtcc
    16501 cggcgccttc ccgggtcccc gcaacggctg accgcacgcc gccctctgcc ccaccgtgcc
    16561 ggtcgcacgg cggggcagtc ccctgcccgg acccgaaagg cccggaccct cgaagggcct
    16621 cccccggggc ctcagccgat gtcgggcggg tcgatcctga tgcgcaccgg gtcggtcgcc
    16681 cccttggcca tgcgggccgc gagcgccgtc ttcagcgcgc gggcgagcgc cgccccccgc
    16741 cccgggacca cccggatcag ggcccgctcc caggtctcgc ccggcggggc gtcccccggt
    16801 cgccggggcc tgccgggctc ggccgacggg accggcaccg gacccaggat ctcggcctcc
    16861 ggcggcagcc cggcggtccg gaggaacgcg gccagggcct cggcggggcc ggtcgccgag
    16921 gccatccggg agaccggagg gaagcccagc tcggcccgct ccgccagctc ccgccgggcg
    16981 aatcccgccg ggtcccagcg gaccagcgcc tgcaccgcgc gctccgtcgg ttcggccacg
    17041 atcaccaccg tgccgccctc gtcctggccc cggaccagcg cgcccgccgc cgtccaccgg
    17101 cgcagcgcct cctcccccgc ccgcaggtcg ggccggccga gcatggccca gccgtccagg
    17161 agcagggccg ccgcgtatcc gccgtcggcg acgggctccg cgccgggggt ggagacgacc
    17221 agggcaggtg cgtcgggcac cgcgtccagg atgtggtcgc gccccgaggt gcggacgggc
    17281 acggcgggaa aagcccggcc cagctcctcc gcggtgcggc gggcgccgac gatctgggcg
    17341 cgcagccggg tcgagccgca ctccgcgcag tgccaggccc gctcggcccg cccgcaccag
    17401 gtgcagttca gatcctgctg gtccggggcc tggagagggc ccgcgcagtg ccggcagcgg
    17461 gcgggggtgc ggcagcgttc gcaggcgagg cggggtgcgt aaccccggcg gggcacctgg
    17521 accagcaccg gaccgctgcg caggccgtcg cgcacggtct gccaggcgag gctgggcagc
    17581 cgggcggacc gggcggcgcc gtcccgggcc agctcgccgt ccccgaccgt acggacgagg
    17641 ggcgcggccc ggcgcagccg ctcccggtcg gcgaggagcg gcagcgccca gccgctctcc
    17701 acgagctggg cggcctcgac ggtgcagccg gtcccgccga ggaggaagcc gcagcggccc
    17761 tgtgccgccc gcagctccag gacctcgcgg acatgcggga agggcgcgtt gtcgtcgctg
    17821 tggctggagt ccccgtcgtc ccagatgacg accaggccga ggtcctggac gggggcgaac
    17881 atggcggccc tggtccccac gaccgcccgc accgagcccc ggcgcaccgc gagccactgc
    17941 cggtagcgct tctcggggcc ggagtcggcg gtcagcaggg cgtgccggcc gttgccgagc
    18001 gcctcggtca gggccgcgtc gacccgtccg gcggcccgtc cgtccgggac gacgacgagc
    18061 gcgccgcgcc cggaggagag cgtcgccgcg acggccccgg cgatctcggc gggccagtgc
    18121 gggccgggca gggcggtcca caccgcgcgc ggcgcaccgc cgtcagccag tgcgcgcagg
    18181 aaggccgggc cctggccgta ccgctcccag gtgcccggct cgggggcctg gggcgggggc
    18241 agcgggtccg gggagggcct ggactcggcg cggccgttgc ggggcgggac tgcgagctga
    18301 aggacgtcgg cgaggctgcc cgcgtaccgg tcggcgacgg cgcggcagag tgcgagcagg
    18361 tcgggcccga ggaccggctc cggggagacc acggaggcga gggcggccag tgcgccctga
    18421 tagtcggatt cggcgaggcg ctcgacgatg aagccgtcga tcaggccgcc gccctcacgc
    18481 cgtccgccct ggacgttgcg cccgcccgcg ccgaagcgca cccggacgcg gacgcccggc
    18541 tgtgcgtcgg cgtccagctc ctcggggacg gcgtagtcga agtactggtc gaggtggagg
    18601 acgcccttgt tgaccaggac gcgggcgacg ggcagttcct cggcgagcgc ggcgccccgc
    18661 caggtccgcg gcttggcacg gggcaccttc gcccggcgca cggtctcccg gatcagcgca
    18721 agctgctccg gcgccccggc accgggttcg gcggactgct cgttctcgct gctcacagct
    18781 gaattcctac cagagagcac tgacagcggc gggggcacgg cagcggggcc cggccaccgc
    18841 gttcggtgtc cgggccccgc tgtcgtactc gatgacaccc gccccgctgt cgtacgcggg
    18901 cggtttcgct acagaccggc ggcggcgcgc agggcgtcca cgcggtcggt gcgctcccag
    18961 gtgaagtcgg gcagctcacg gccgaagtgg ccgtaggcgg cggtctgggc gtagatcgga
    19021 cggagcaggt cgaggtcccg gatgatcgcg gccggacgga ggtcgaagac ctcgccaatc
    19081 gcgttctcga tcttctcggt gtcgaccgcg gcggtgccga aggtctccac gaacagtccg
    19141 acgggctcgg ccttgccgat cgcgtacgcg acctggacct cgcagcgcgc ggcgagaccg
    19201 gcggccacca cgttcttggc gacccagcgc atcgcgtacg cggcggagcg gtcgaccttg
    19261 gacgggtcct tgcccgagaa ggcgccgccg ccgtgccggg ccatgccgcc gtaggtgtcg
    19321 atgatgatct tgcggccggt gaggccggca tcgcccatcg ggccgccgat ctcgaagcgg
    19381 ccggtcgggt tcaccaggag gcggtagccc tcggtgtcca gcttgatgcc gtcctcgacg
    19441 agctgcgcga gcacgtgctc gacgacgaac tcgcggatgt cgggtgcgag cagcgagtcc
    19501 aggtcgatgt ccgacgcgtg ctgcgaggag acgaccaccg tgtccagccg gaccgccttg
    19561 tcaccgtcgt actcgatggt gacctgggtc ttgccgtcgg ggcgcaggta ggggatggtc
    19621 ccgttcttgc gcacctcgga cagtcgccgg gagaggcggt gcgcgacgtg gatcgggagc
    19681 ggcatcagct ccggcgtctc gtcgcaggcg tagccgaaca tcaggccctg gtcgcccgcg
    19741 ccctgcttgt cgagctcgtc ctcgtcgccc tcgacccgct tctcgtacgc ggtgtcgacg
    19801 ccctgtgcga tgtccggcga ctgcgcgccg atcgacaccg agacgccaca ggaagcaccg
    19861 tcgaagccct ttttggagga gtcgtaaccg atctccagaa ccttgttgcg cacgaggttg
    19921 gggatgtcgg cgtaggcctt ggtggtgacc tcgcccgcga catgcaccag accggtggtg
    19981 atcaaggtct cgacggcgac gcgcgaggcg gggtcctcgc gcaggagcgc gtcgagaatc
    20041 gtgtcgctga tctggtcagc gatcttgtcg gggtgaccct cggtgacaga ttccgaggtg
    20101 aagagacggc gggacacatc gctccctggg gttgcagcgg ctgctggctg atcatgggtg
    20161 gtacgaccga gagctgcgct cggcgcgtac cgtcggccag tttatcggtc gcatcaggcg
    20221 accggggcag gtgtctcgcc ctttgggagg ttcgtgacgt gcgccacgcg gggctccagt
    20281 aggacaatcc acccttcctg gcctttgttt taggccttat gggacgattt cgctcgcccg
    20341 gagggttgat tgtgaaatcg gctggaacct tcccgcgacg agatcccaga ccgtgtcggc
    20401 gagcgcttcc ttgggaccgt acggcaccgg cgtctccgtg ccgtcggcgg cgaggacgac
    20461 cgcttcgttc tcctccgagc cgaaggtctt gcgctccccc acctcattga ccacgagaag
    20521 gtcgcagccc ttgcgtcgga gcttcgcacg gccgttgacc agcacgtcgt cggtctcggc
    20581 ggcgaatccg acgacgatct ggtccggacg ggcccgctcg ccggagacct cggcgaggat
    20641 gtcggggtta cggaccaggg ggacggcggg cgcctcctcg ccgtccttct tcttgatctt
    20701 gccggaggcg tacgcggcgg ggcggaagtc ggccaccgcg gccgccatca ccacgacgtc
    20761 cgcgtcgggg gcggccttca gcactgcctc gcgcagctgg acggcggtgc cgacgcggag
    20821 gacgtcggcc ccggccgggt cgggcagccc ggtgttggcc tcgatcaggg tgacccgggc
    20881 cccccgggcc acggcggtgc gcgccagcgc gtacccctgc ttgccggagg agcggttgcc
    20941 caggaagcgc accgggtcga gcggctcgcg cgtgcctccg gcgctgatca ccacatggcg
    21001 gccggcgagg tcgggctcgg tgaccccgcg cgccagcacc cggcggcaga cctcgtagat
    21061 ctcgccgggg tcgggga
//
