LOCUS       NZ_LIVW01000005        22214 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02115 scaffold5, whole genome shotgun sequence.
ACCESSION   NZ_LIVW01000005
VERSION     NZ_LIVW01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02115
  ORGANISM  Streptomyces sp. CB02115
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 630329)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630329)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905645.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,651
            CDSs (total)                      :: 7,572
            Genes (coding)                    :: 7,475
            CDSs (with protein)               :: 7,475
            Genes (RNA)                       :: 79
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 34 of 97
            Pseudo Genes (incomplete)         :: 79 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 23 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:09:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 218555
            Orig. end                         :: 240769
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVW01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(153..950)
                     /locus_tag="AMK28_RS26130"
                     /old_locus_tag="AMK28_25750"
     CDS             complement(153..950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766343.1"
                     /locus_tag="AMK28_RS26130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25750"
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_073743747.1"
                     /transl_table=11
                     /translation="MAEGQWSPGRKEADADEFRPVLDIVEPARQRRLTVLLRLLLLIPH
                     FIVLFVLHIAAFFTVIVGWFAALVLGRLPDPVFRFLTGVLGYDMRVSASDMLLIDRYPP
                     FALTPPTDYPVQIEVRPTPLNRLAVLFRVFLMIPAAIVQSLAVYGWWALAFVWWLITLC
                     LGRMPRPLFEATAATLRYRMRFSAYVMMLTPAYPKGLFGDDDLAVAPERSRSATRPLVL
                     SSAAKWLVVLFLVLGLAGHVISSVTASTSDDIDDTYDTRLVGP"
     gene            complement(1063..1827)
                     /locus_tag="AMK28_RS26135"
                     /old_locus_tag="AMK28_25755"
     CDS             complement(1063..1827)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458443.1"
                     /locus_tag="AMK28_RS26135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25755"
                     /product="VanZ family protein"
                     /protein_id="WP_073743749.1"
                     /transl_table=11
                     /translation="MLVRGAVLTVVLLGLVAFSVLLAKVTLTPSPASEDLVTANLRPGR
                     SLRQYAEDYTFLAACKQAGGNLLLGVPFGLLLPFFVPRRLRMIRTTLLTAVAMAVVELI
                     QGALVEGRAFDVDDVILNTAGALLGYFVLGRRISHRYYTYTDDSGSPGPSAEKPEAEPK
                     RAPGPAARTKAVRKGTAPTKTARTKAAPTKTVPTKTARTKAGQRDRPKPAASAPAKKRG
                     ARTGRTDGAASGGPRATGSGAVRSLLDRLRGR"
     gene            1976..2476
                     /locus_tag="AMK28_RS26140"
                     /old_locus_tag="AMK28_25760"
     CDS             1976..2476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971171.1"
                     /locus_tag="AMK28_RS26140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25760"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_073744232.1"
                     /transl_table=11
                     /translation="MSAHTKRDLLDEADRLRSEGRPEEARERLLALTAQYPDDAEVACR
                     TAWIHDVLGLESEAVPYYERALAHPELASEDRHGVLLGLGSTYRILGRYGQAVETLRRG
                     VEEFPDDGSLRAFLAMALYNTDEHHEAMRLLLELTAATSRDPRVQQYRRAMEHYAKDLD
                     ETV"
     gene            2642..3325
                     /locus_tag="AMK28_RS26145"
                     /old_locus_tag="AMK28_25765"
     CDS             2642..3325
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458446.1"
                     /locus_tag="AMK28_RS26145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25765"
                     /product="YoaK family protein"
                     /protein_id="WP_073743751.1"
                     /transl_table=11
                     /translation="MPWHREWALLLLSGASGAADAFVFLCVGQVFAGVMTGNLVLLGAS
                     AAGAGEDGVALKVAVALGAYFCGVAAGALLTGRRGPRVRVLLGAEVVLLGAAAALWGLE
                     LVTSYGDRLGLLALVAVAMGVQGRVRVTPTNYFTGTLTSLAGRVALRELRGGDGWVLGR
                     LAAVVAGAALAALAERWWSPGAALGAVVMAAGALVLETAPYRGGRPGPGKGKPRPDRGN
                     PAGAV"
     gene            complement(3549..3809)
                     /locus_tag="AMK28_RS26150"
                     /old_locus_tag="AMK28_25770"
     CDS             complement(3549..3809)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606682.1"
                     /locus_tag="AMK28_RS26150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25770"
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_032794154.1"
                     /transl_table=11
                     /translation="MKSRIHPVSRPVVFRDRAADVAFLTRSTADSGERVTWEDGNSYPV
                     IDVDTSSASHPFYTGGSQVLDTAGRVEQFRRRYGTGETAGS"
     gene            complement(3874..4038)
                     /gene="rpmG"
                     /locus_tag="AMK28_RS26155"
                     /old_locus_tag="AMK28_25775"
     CDS             complement(3874..4038)
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192346.1"
                     /locus_tag="AMK28_RS26155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25775"
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_032794160.1"
                     /transl_table=11
                     /translation="MARSETRPVVTLRSTVGTGRSYVTRKNRRNNPDRLELRKFDSAAG
                     RHVLFREVR"
     misc_feature    4082..4097
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    4084..4098
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.29"
                     /tool="antismash"
     misc_feature    complement(4086..4097)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    4180..4195
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            4349..5776
                     /locus_tag="AMK28_RS26160"
                     /old_locus_tag="AMK28_25780"
     CDS             4349..5776
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="AMK28_RS26160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25780"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_073743753.1"
                     /transl_table=11
                     /translation="MPSPLFADRPAPQLPAHDAVDALIHRTRQLRGDVDAVRRDAVVFD
                     EDDPQLRWQRALCELAVQHLDSLDQHLGQLRAGLPDPRADDAPRAVGAPDDPGAGTPLN
                     RVGSAEWNLLTDESSWSEELYEIFGRPPGSTPLSLDDLPSVLLPEDQPVLTAMVTGCLV
                     DGRPMDGEFRIVRPDGRTRTLHMTGEPVLDAEGCTASMWAVLRDVSELRRSEQAVSRDR
                     ASVRREEHIERTEHRMAVELQEAVLPPWRGPLRLPSQGPGALDIAAHYLPSESSGLIGG
                     DWYDAMELPDGRTLLTVGDLTGHGIPATSAMAMMLGALRGMAVAGIEPGALMGHLNQVL
                     ETSIQPALGSALCCRFDPDTSILSWAQAGHPAPLLFRHGSGRLLPPPDGMLLGAASNVL
                     FEQDEVRLYPGDVLVLHTDGLTRRGNRGAGPEALFALAPRFADARTAQECVRSVVEEFG
                     GAERLDDACVLVARIGA"
     gene            complement(5828..7318)
                     /locus_tag="AMK28_RS26165"
                     /old_locus_tag="AMK28_25785"
     CDS             complement(5828..7318)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606686.1"
                     /locus_tag="AMK28_RS26165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25785"
                     /product="hypothetical protein"
                     /protein_id="WP_073743755.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDSGTEHNPDQL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSTIAGPMYDWLHSDPALVADAPR
                     TDDPLHADPAGLDRYEAAPVGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQASMGRGQA
                     MRRTLGEAEELFISDKSDVPPPSWMQMFDEADMHGMQALAFRTLAEHDQGAAIIAQRHA
                     KQALELRVNGRQRSKIFDYISLASACFIANDPDQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFAGHAGIQDLREEIELSMPPSQKKAKGTQT"
     gene            7550..8686
                     /locus_tag="AMK28_RS26170"
                     /old_locus_tag="AMK28_25790"
     CDS             7550..8686
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="AMK28_RS26170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25790"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_073743756.1"
                     /sec_met_domain="APH (E-value: 5.3e-18, bitscore: 60.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGAGGGPYLAPHAGAPVQGPGRARRASG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGTTGRATAV
                     AKCLLDHSPAWTERFRHEIAAYRAFVRHRPPVRAPRLIAADPENCTLVIERMPGRVAAL
                     TRHPAEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYASRIARYHELGLFTDRDLGD
                     LQKLLHGLAHAGGKQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWA
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRTMREAPATGAG
                     ADRPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    7871..7873
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9163..9837
                     /locus_tag="AMK28_RS26175"
                     /old_locus_tag="AMK28_25795"
     CDS             9163..9837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="AMK28_RS26175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25795"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_073743758.1"
                     /transl_table=11
                     /translation="MPRISTLRITRSHKIATAVLVAAGSVSAIAATGGTSEAQTTATRS
                     SISVEPVAAAGIPTAKDAAAKKAAQETAAKEAAAKKAVAARKATAEKDAAEARSEKQAA
                     NRSTERKAVTPKKFANNLDGWIRESLDIMKKKDIPGSYEGLHRNIMRESSGNPNAVNDW
                     DINAQNGIPSKGLLQVIQPTFDAYHVKGTPKKLTDPVANITAAANYAADRYGSIDNVDS
                     AY"
     misc_feature    complement(9885..9899)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.2"
                     /tool="antismash"
     gene            10001..12214
                     /locus_tag="AMK28_RS26180"
                     /old_locus_tag="AMK28_25800"
     CDS             10001..12214
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956438.1"
                     /locus_tag="AMK28_RS26180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25800"
                     /product="terpene synthase family protein"
                     /protein_id="WP_073743760.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-85, bitscore: 283.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTRAWARSMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDREGGKRY
                     LDRLPAFMPMERGAPTPDPENPVEAGLADLWARTVPSMSDAWRARFAEATENLLNESLW
                     ELANIHEGRIANPVEYIEMRRKVGGAPWSAGLVEYAANAEVPAPVADARPLRVLRDAFS
                     DGVHLRNDLFSYQREVEDEGENSNGVLVLEKFLGCSTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLCAEKSLDPTQTAAVLAYVKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVPGFG
                     MSAASIRFTFRSETSRARGQSHVPYQHVGPSLLPGFDLPFGTTLSPHLEGARVRIVDWA
                     RRMGILEAQPGVPGSNIWDEERLVAIDLPLCAAGLDPDATPDELDLSSGWLAWGTYGDD
                     WFPVVHGRTRDLAGARLANERLSLFMPLDGEGTPEPVNALERSLGDLWRRTAAPMDAGG
                     RRTFRASIESMTESWLWELANQAQNRIPDPVDYVEMRRATFGSDLTMSLCRLGHGRKVP
                     DEVYRSGPMRSLENAAADYACLMNDLFSYQKEIEYEGEVHNGVLVVQNFFGVDYPTGVA
                     IVHDLMNSRLRQFLHVAEVELPVLYEDFGLDAEAREILAGYVQELKHWIAGILIWHRGC
                     RRYREEDLRRGHGTPWHISGPTGLGTSAAQVTRLMAQLAGSPV"
     gene            complement(12292..12849)
                     /locus_tag="AMK28_RS26185"
                     /old_locus_tag="AMK28_25805"
     CDS             complement(12292..12849)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956439.1"
                     /locus_tag="AMK28_RS26185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25805"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_073743761.1"
                     /transl_table=11
                     /translation="MHAPQTDGRLLKGERRKEELIEATLQVVAREGVAGVSHRAVAREA
                     GLPATAAAYHFTSIDDLLTAALTRCMEQDAQRMLRLAEEADGGPEGVTALAELMEKVVK
                     GPGRLLAEYELYLLAARRPELRGPTRHWLEAISAYGHRYTDDPVRVRVLKGVIDGLLLQ
                     GLLTDTPPTAAEFEAVLRHVLL"
     gene            complement(12905..14164)
                     /locus_tag="AMK28_RS26190"
                     /old_locus_tag="AMK28_25810"
     CDS             complement(12905..14164)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458464.1"
                     /locus_tag="AMK28_RS26190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25810"
                     /product="MFS transporter"
                     /protein_id="WP_073743763.1"
                     /transl_table=11
                     /translation="MANPYGVLFRTPGSRAFTAAGFVARMPLSMAGIGIIAMVSQMRGD
                     YGLAGAVSATFTLSMALCGPRISRAVDRRGQSRVLPPVAGLSVLALGALLLCARYDAPA
                     WTLFGCAAVAGAMPNMAAMVRARWTHALKGSDRLHTAYSLESVVDELTFVVGPALSVAL
                     CTALFPEAGPLVAGVLLVLGVLLFVPQKRTEPPVARPADGHPHTGSAIRSGALRLLALT
                     LVAGGAIVGTVDVVSVSFAEQQGSPAGAGIVLAVYAAGSAVAGLVFGTLRLRTPLPRLL
                     VIGTAGTALTTLPLLLVGDLVTLSAAVFLPGLFFAPTMIVVMGLVERTVPPAVLTEGMT
                     WAITGLSVGVASGAAVSGAIVDRLGPGGGFVVAVAAGAAALLTASCARRPLERSLRQRA
                     ERDAEGPAEEQAEAPGRAAH"
     misc_feature    14232..14246
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            complement(14379..14879)
                     /locus_tag="AMK28_RS26195"
                     /old_locus_tag="AMK28_25815"
     CDS             complement(14379..14879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="AMK28_RS26195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25815"
                     /product="hypothetical protein"
                     /protein_id="WP_003971159.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPEGSPARETEEGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     misc_feature    14882..14892
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(14956..16122)
                     /locus_tag="AMK28_RS26200"
                     /old_locus_tag="AMK28_25820"
     CDS             complement(14956..16122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="AMK28_RS26200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25820"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_050361618.1"
                     /transl_table=11
                     /translation="MSKEPVAVVGIGQTKHVAARHDVSIAGLVREAAVRALEDAGLAWS
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDAVGS
                     LVAYKDRRNALKNPYAHLHDHDITLEKVRAAPMLWDPIRYSETCPSSDGACAMILTDRE
                     GAARSPHPPAWVHGGAMRSEPTLFAGKDFVSPQAGKDCAADVYRQARITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFADEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGRAGEHQIDGATRALGHAYGGGAQFFAMWLVGAEPPPG"
     gene            complement(16115..17167)
                     /locus_tag="AMK28_RS26205"
                     /old_locus_tag="AMK28_25825"
     CDS             complement(16115..17167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515105.1"
                     /locus_tag="AMK28_RS26205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25825"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_056708039.1"
                     /transl_table=11
                     /translation="MRDVAIVAFAQTTHRRRTDELSEVDLLMPVLHEVLGATGLKANEI
                     GFTCSGSADYLAGRAFSFTMALDGVGAHPPISESHVEMDGAWALYEAWVKIQTGEADTA
                     LVYSYGKSSPGRVRDVLTRQLDPYYLAPLWPDSVALAALQAQALIDAGATDEGALAEVA
                     ARNRTAAADNPHAQLTGDVPAGDYLVHPLRTGDCPPIGDGAAAVVLAAGDTARALCARP
                     AWIRGIDHRIEAHALGVRDLTDSPSARLAAERAGVFERPVDTAELHAPFTSQEVILRKA
                     LGLGDEVRVNPSGGALAANPVMAAGLIRLGEAAARIHRGESDRALAHATSGPCLQQNLV
                     AVLEGESAHV"
     gene            complement(17168..18115)
                     /locus_tag="AMK28_RS26210"
                     /old_locus_tag="AMK28_25830"
     CDS             complement(17168..18115)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="AMK28_RS26210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25830"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_073743765.1"
                     /transl_table=11
                     /translation="MSDVLSAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRTEDGTV
                     LVPPVEYDPVTANEIRDLVEVAPTGTVTTWAWNPSPGRDQPLGTPFAWVLVRLDGAGTA
                     LLHALDAPRPDAVRTGMRVRIRWAATRTGAITDIACFEPCDGEPGASEPAPHTGEFPEP
                     VTGIVTPARLDYVHTPGRAQSAYLTALEGHRTVGERCPACRKVYVPPRGACPTCGVATA
                     EQVEVGPRGTVTTFCIVNIKAKNLDIEVPYVYAHIALDGADLALHGRIAGIPYDQVRMG
                     LRVEPVWVEGARHPDHYRPTGEPDADYDTYKELV"
     gene            complement(18160..18960)
                     /locus_tag="AMK28_RS26215"
                     /old_locus_tag="AMK28_25835"
     CDS             complement(18160..18960)
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 5.1e-53. Score:
                     171.8. Matches aSDomain:
                     nrpspksdomains_AMK28_RS26215_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956444.1"
                     /locus_tag="AMK28_RS26215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25835"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_073743767.1"
                     /transl_table=11
                     /translation="MGGTEHLTVRREGATLVLTLNRPQARNALSLPMLVGLYDGWLAAD
                     ADDTVRSVVLTGAGGAFCAGMDLKALAGGGMEGERYRERMTADPDLHWKAMLRHHRPRK
                     PVIAAVEGPCVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPRTH
                     ALEMLLTGRPYTADEAAAIGLIGRVVPDGTALEEALVVAERVNACGPLAVEAVKASVYE
                     GAELTESEALAAELKRGWPVFATEDAKEGARAFAEKRPPVYRRA"
     aSDomain        complement(18187..18933)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK28_RS26215_ECH.1"
                     /evalue="5.10E-53"
                     /label="AMK28_RS26215_ECH.1"
                     /locus_tag="AMK28_RS26215"
                     /protein_end="258"
                     /protein_start="9"
                     /score="171.8"
                     /tool="antismash"
                     /translation="RREGATLVLTLNRPQARNALSLPMLVGLYDGWLAADADDTVRSVV
                     LTGAGGAFCAGMDLKALAGGGMEGERYRERMTADPDLHWKAMLRHHRPRKPVIAAVEGP
                     CVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPRTHALEMLLTGR
                     PYTADEAAAIGLIGRVVPDGTALEEALVVAERVNACGPLAVEAVKASVYEGAELTESEA
                     LAAELKRGWPVFATEDAKEGARAFAEK"
     misc_feature    19014..19029
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    19015..19031
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    19019..19033
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.75"
                     /tool="antismash"
     misc_feature    complement(19036..19049)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            19127..20749
                     /locus_tag="AMK28_RS26220"
                     /old_locus_tag="AMK28_25840"
     CDS             19127..20749
                     /NRPS_PKS="Domain: AMP-binding (8-438). E-value: 1.2e-66.
                     Score: 216.9. Matches aSDomain:
                     nrpspksdomains_AMK28_RS26220_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382252.1"
                     /locus_tag="AMK28_RS26220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_25840"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_073743769.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-70, bitscore:
                     233.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDAVPDREALLYVDHPGTGAERRLTYAELDAAA
                     NRIAHHLIDAGIRPGEHLGLHLYNGVEYLQTVLGALKARIVPVNVNYRYVEEELVYLYR
                     DADLAALVFDGEFDERVAAAAPQAPGLRHLVRVGPAPAAPPAVPVVPFTEAERSGGSGR
                     GFAPRSADDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKAPQELAERVAA
                     GGDGITFFPTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPAEVLRTIEKEKVTSVSLVG
                     DAMLRPLIDCLNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSES
                     GFNGTATADSGPERGFRVQVNARTAVVDPATYEPVAPGEPGRIAQRGHVPLGYYNDPAK
                     TADTFFRRGEERWVLLGDMATVDADGIVTVLGRGSQCINTGGEKVYPEEVEQALKSHPD
                     VYDALVAGVPDERWGNRVAAVVQLRENAEALTLEAVQAHCRTRLAGYKIPRALVLTDRI
                     QRSPSGKADYRWAKAVAAGAGQR"
     aSDomain        19151..20440
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK28_RS26220_AMP-binding.1"
                     /evalue="1.20E-66"
                     /label="AMK28_RS26220_AMP-binding.1"
                     /locus_tag="AMK28_RS26220"
                     /protein_end="438"
                     /protein_start="8"
                     /score="216.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDAVPDREALLYVDHPGTGAERRLTYAELDAAANRIAHHLI
                     DAGIRPGEHLGLHLYNGVEYLQTVLGALKARIVPVNVNYRYVEEELVYLYRDADLAALV
                     FDGEFDERVAAAAPQAPGLRHLVRVGPAPAAPPAVPVVPFTEAERSGGSGRGFAPRSAD
                     DQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKAPQELAERVAAGGDGITFF
                     PTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPAEVLRTIEKEKVTSVSLVGDAMLRPLI
                     DCLNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSESGFNGTATA
                     DSGPERGFRVQVNARTAVVDPATYEPVAPGEPGRIAQRGHVPLGYYNDPAKTADTFFRR
                     GEERWVLLGDMATVDADGIVTVLGRGSQCIN"
     CDS_motif       19646..19696
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK28_RS26220_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="AMK28_RS26220"
                     /protein_end="190"
                     /protein_start="173"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     CDS_motif       20291..20338
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AMK28_RS26220_0002"
                     /evalue="3.70E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="AMK28_RS26220"
                     /protein_end="404"
                     /protein_start="388"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VPLGYYNDPAKTADTF"
     misc_feature    21336..21349
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(21920..21929)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gtcctgggcg cctggtcctg ggccgggctc gccgccgaac tcggcaggtt cgacgtggac
       61 atcgaggtcg tcggacccga cgggctgagg gaggccttcg cccggttggc ccgccgctgt
      121 gccgtcgcgg cggggacggg gcccggcggc cctcagggac cgacgagccg cgtgtcgtag
      181 gtgtcgtcga tgtcgtcgct cgtcgatgcg gtcacggacg agatgacgtg acccgccagg
      241 ccgagcacca ggaagagcac gacgagccat ttcgcggcgc tgctcaggac cagcgggcgg
      301 gtggcggagc gcgaccgctc cggggccacg gcgaggtcgt cgtcgccgaa caggcccttg
      361 ggataggcgg gggtgagcat catgacgtac gcggagaacc gcatccggta gcgcagggtg
      421 gccgccgtcg cctcgaacag cggccggggc atccggccga gacacagcgt gatcagccac
      481 cagacgaagg ccagcgccca ccacccgtac acggcgagac tctggacgat cgccgccggg
      541 atcatcagga agacgcggaa cagcaccgcg agccggttga gcggggtggg ccgcacctcg
      601 atctgcaccg gatagtcggt cggcggggtc agggcgaagg gcgggtagcg gtcgatgagc
      661 agcatgtcgc tcgccgagac gcgcatgtcg tagccgagga cgccggtcag gaagcggaag
      721 acggggtcgg gcagccgtcc cagcaccagc gccgcgaacc atcccacgat gacggtgaag
      781 aacgccgcga tgtgcaggac gaacagcacg atgaagtgcg ggatcagcag caggagtcgc
      841 aggaggacgg tcagccggcg ctgacgggcc ggttcgacga tgtccaggac gggcctgaac
      901 tcgtccgcgt ccgcctcctt gcggcccggg ctccactggc cttcggccat gtcgctcctc
      961 ctcggcaggg gatccgggcg ccatccgcgc gcaggacgtg tccccaccgt gcgtccgctc
     1021 cgggccgccc gcaaacggcc cggcccgaac gggtgcccct gctcagcgcc cgcggaggcg
     1081 gtcgagcagg gagcggacgg cgccggaccc ggtggcgcgc gggccgccgc tcgccgcgcc
     1141 gtcggtcctc cctgtgcggg cgccgcgctt cttggcgggg gccgaggccg ccggcttcgg
     1201 ccggtcccgc tgtccggcct tcgtacgggc ggtcttcgta gggacggtct tcgtaggggc
     1261 ggccttggtg cgggcggtct tcgtaggagc ggtcccctta cggacggcct tggtgcgggc
     1321 ggccggcccc ggcgcacgct tcggctcggc ctcgggcttc tccgccgacg ggccggggga
     1381 tccggagtcg tcggtgtagg tgtagtagcg gtggctgatc cggcggccca gcacgaagta
     1441 ccccagcagc gcgcccgccg tgttgaggat gacatcgtct acgtcgaagg cgcgcccctc
     1501 gaccagggcc ccctggatca gttcgacgac ggccatggcg acggcggtca gcagcgtcgt
     1561 ccggatcatg cgcaggcggc gtggcacgaa gaacggcagc aggagtccga acggcacgcc
     1621 gagcagcagg ttcccgcccg cctgcttgca cgcggcgagg aaggtgtagt cctcggcgta
     1681 ctggcgcagc gagcggccgg ggcggagatt cgcggtgacg aggtcctcgg atgccggtga
     1741 cggcgtgagc gtcaccttgg ccaggaggac ggagaacgcc acgagtccca gcagcaccac
     1801 cgtcaggacc gccccacgca ccagcacacg tacccatgtc ccccggtctg tacggggatt
     1861 cgcctctgct gtcatggccg acggatgccc ccgcccggcc ggaacacaca cctggacggt
     1921 cccgtggagc gaaaatctca tgttgccgtc cgcgcccgcc tgcgacgatg tgcgcatgag
     1981 cgcacacacg aagagggacc tgctggacga ggccgaccgg ttgcggtcgg agggccggcc
     2041 cgaggaggcg cgcgaacggc tcctcgccct gaccgcccag taccccgacg acgcggaggt
     2101 ggcctgccgg acggcgtgga tccatgacgt gctgggcctg gagtcggagg cggtgccgta
     2161 ctacgagcgc gctctggcgc atccggaact cgcttcggag gaccggcacg gggtgctcct
     2221 ggggctgggc agtacgtacc ggatcctcgg gcggtacggg caggcggtgg agacgctgcg
     2281 ccggggcgtc gaggagttcc cggacgacgg ctcgctccgg gcgttcctgg cgatggcgct
     2341 gtacaacacc gacgagcacc acgaggcgat gcgcctgttg ctggagttga cggccgcgac
     2401 cagccgggac ccgcgcgtcc agcagtaccg acgggcgatg gagcactatg cgaaggacct
     2461 cgacgagacc gtgtgacccg tgcgggccgg ggcggtcgtc cacggcgcgc cgtatcgcgc
     2521 cggacgcacc ggtccgggag cggtggatgc cgagaatgct cgggtgccca ccgctccccc
     2581 ggcgcctccg ccgtccccgt ctccctctcc ctcctcctcc ggtgcttccc gggccggtga
     2641 tatgccgtgg catcgcgagt gggcgctgct tctgctgtcc ggggcctccg gcgcggcgga
     2701 cgcgttcgtc ttcctgtgcg tggggcaggt cttcgccggg gtgatgacgg ggaacctggt
     2761 gctgctcggg gcttcggccg ccggtgcggg cgaggacggc gtggcgctga aggtggctgt
     2821 cgctctgggg gcgtacttct gcggggtggc ggcgggcgcg ctgttgaccg ggcggcgagg
     2881 tccccgggtc cgggtgctgc tgggggcgga ggtcgtcctg ctgggggcgg cggccgcgct
     2941 gtgggggctg gagctggtca cgtcgtacgg cgaccggctc gggctgctgg ctctggtggc
     3001 ggtcgcgatg ggcgttcagg gtcgcgtccg ggtgacgccg acgaactatt tcaccgggac
     3061 gctgacctcg ctcgcgggtc gcgtcgcgct gcgggagctg cgcggcgggg acggctgggt
     3121 gctggggcgg ctggccgcgg tggtggccgg ggcggcgctc gcggcactgg ccgagcggtg
     3181 gtggagtccg ggggccgcgc tgggcgcggt ggtgatggcc gcgggcgctc tggtgctgga
     3241 gacggccccg taccggggcg gccggccggg gccgggcaag gggaagcccc ggccggatcg
     3301 ggggaatcca gccggggcgg tctgagtgcg ggcgtgaagg gcggtcgcct ctcggcggag
     3361 ggctccacgg ggcttcggcg gtgcgatctt ccccatgggc tacaggtgag gcccggggac
     3421 actgtccccc tcactcccac gtatagatga acgataaacc atcctgggcc gttcccggga
     3481 acccgccctc gcggatgtga tccacggcac ggactcccgg gcttcctccc tggtcaggac
     3541 tcgttcggtc agctcccggc tgtctcgccg gtgccgtaac ggcgccggaa ctgctcgacg
     3601 cggcccgccg tgtcgagcac ctggctgccg ccggtgtaga acgggtggct cgccgacgag
     3661 gtgtccacgt cgatgacggg gtagctgttg ccgtcctccc acgtcacacg ctcgccggag
     3721 tcggcggtcg agcgggtcag gaaggcgacg tcggccgcgc ggtcgcggaa gaccacggga
     3781 cgggacacgg ggtggattcg ggacttcatc gatgcgttcc ttcctcaccg cgggcagcgg
     3841 tgacgtacaa ggggacaggt ctcttccggg cggtcagcgg acctcgcgga acaggacgtg
     3901 ccggccggcg gcggagtcga acttgcggag ctccagccgg tcggggttgt tgcggcggtt
     3961 cttgcgtgtc acataactcc ggcccgttcc gacggtggac cggagggtga cgaccggcct
     4021 ggtctcgctg cgtgccatgg gcgcctcccg atgcctctgc cgaccccgct cccgtatcgg
     4081 gaatgggatt cgttttcgtt ctggtgaggt aacgcgagcc gccccctcgg cattcccact
     4141 ccgcgacgca ccccgaaccg caggtccaac tcgccccaaa cgtaagcctg ttcggatacc
     4201 caccgtcccg gatagccgct ggcatatgcc agacgcaaga acgcatcgag tgttgccaaa
     4261 tcccttacga cccaccgtgg cctgtgcgac agtcggtagc ggtccaccct tcagaaccgg
     4321 ctaggccgcg cctgtatcgg agtacgagat gccgtccccc ctcttcgcgg accgccccgc
     4381 accacagctt cccgcgcatg acgccgtcga cgccctgatc caccggacgc gtcagctgcg
     4441 cggggatgtg gacgccgtgc ggcgggacgc cgtcgtgttc gacgaggacg acccccagct
     4501 gcgctggcag cgcgccctgt gcgagctggc ggtgcagcac ctggacagcc tcgaccagca
     4561 cctgggccag ctccgggcgg gtctgccgga cccgcgcgcc gacgacgccc cccgtgctgt
     4621 cggggccccg gacgacccgg gggccggtac cccgctgaac cgggtgggca gcgccgagtg
     4681 gaacctcctc accgacgagt ccagctggtc cgaggagctg tacgagatct tcggcaggcc
     4741 gcccgggtcc acgcccctct ccctcgacga cctgccgtcc gtgctgctgc ccgaggacca
     4801 gccggtgctg accgccatgg tgacgggctg cctcgtcgac ggccggccga tggacggcga
     4861 gttccgcatc gtgcgtcccg acggccgcac gcgcaccctg cacatgacgg gcgagccggt
     4921 cctcgacgcc gagggctgca ccgcctccat gtgggcggtc ctgcgggacg tcagcgagct
     4981 gcggcgcagc gagcaggccg tgagcagaga ccgcgcgtcg gtacggcgcg aggagcacat
     5041 cgagcgcacc gagcaccgca tggccgtgga gctccaggaa gccgtccttc ccccgtggcg
     5101 cggaccgctg cggctcccgt cacagggccc cggcgccctg gacatcgccg cgcactacct
     5161 cccttccgag tcgagcggcc tcatcggcgg cgactggtac gacgcgatgg aactgccgga
     5221 cgggcgcacc ctgctcaccg tcggcgacct caccgggcac ggcattcccg ccacctcggc
     5281 gatggcgatg atgctgggcg cactgcgcgg catggccgtc gccggcatcg agccgggcgc
     5341 gctgatggga cacctcaacc aggtgctcga aacgtcgata cagcccgcgc tgggcagcgc
     5401 cctgtgctgc cgcttcgacc ccgacacctc catcctttcc tgggcgcagg ccggacaccc
     5461 cgcaccgctg ctcttccgcc acggttcggg gcggctgctg cccccgccgg acgggatgct
     5521 gctcggcgca gcgtccaacg tgctcttcga gcaggacgag gtacggctgt accccggtga
     5581 cgtgctcgtt ctgcacaccg acggcctgac ccgacgcggc aaccggggtg cgggcccgga
     5641 ggcgctgttc gccctcgccc cccggttcgc ggacgcccgt acggcacagg agtgtgtacg
     5701 gagcgtcgtc gaggagttcg gcggggccga gcgcctggac gacgcgtgcg tgctggtcgc
     5761 ccgcatcggg gcatgaggaa gcgcggacgt atcggggcgt gacggagcgc ggagcggcgc
     5821 tgccgggtca ggtctgcgtg cccttggcct tcttctggct cggcggcatc gagagctcga
     5881 tctcctcgcg caggtcctgg atccccgcgt gtccggcgaa ctgcccggtg agccggtaca
     5941 tttcgcgaag ccggtcccag gtgcggtgcg aggaggtctc ccccatcgac accagcgcga
     6001 gccgggcgta ccggtcggcc tgatcggggt cgttggcgat gaagcaggcc gaggccagcg
     6061 agatgtagtc gaagatcttc gaccgctggc gcccgttgac ccgcagctcc agcgcctgct
     6121 tggcatggcg ctgggcgatg atcgcggcgc cctggtcgtg ctcggccagg gtccggaagg
     6181 ccagcgcctg catgccgtgc atatcggcct cgtcgaacat ctgcatccaa ctgggcggcg
     6241 gaacatcgct cttgtccgag atgaagagct cctcggcctc gccgagggtg cgccgcatgg
     6301 cctgcccccg gcccatcgac gcctgtgccc aggcctcgat ggtgcgcagc atcgcctgcg
     6361 tacgcggcag ggtctcgtcg ccggagccgg acttggcgag cttcatcaga tcgagtgcgt
     6421 cgtcggggcg gcccaggtgc accatctggc gtgccgcccg ggagagcgcc tctccggcgc
     6481 gcggccggtc gccgccctcg cgggccgcgt gggcggcgat gacgaagtac ttctgggcgg
     6541 tgggttcgag gccgacgtcg tgggacatcc agcccgccag gacggcgagg ttggcggcga
     6601 cgccccacag gcggcgctgg agatggtcgg ggtggcggta ggcgagcatg ccgcccacct
     6661 cgttgagctg gcccacgacc gccttgcgct ggagtccgcc gccccgggac gcgtcccagg
     6721 cgcggaacac ctcgaccgaa tgctccaggg cctcgatctc ctcggagccg accggcgccg
     6781 cctcgtaccg gtcgagaccg gctggatcgg cgtgcagggg atcgtcggta cgtggagcgt
     6841 cggccaccag agcggggtcg ctgtgcagcc agtcgtacat ggggccggcg atggttgagc
     6901 cggcggcgag cgcggcgccc gcacccacca agccgcgtcg gttgagcatg aggtccattc
     6961 ccgtgaattc ggtgaggacc gctgccgtcc gttcgggcgc ccacggcaat tgatcgggat
     7021 tgtgttccgt cccggagtca cgccgcttcc ccacacgccc gcgtcggccg aacccgaggt
     7081 cctcgatggt cacgacacgg ccgagccgct cggtgaacag agccgccagc acttcgggca
     7141 cgggatcacg gggggattcc cccatgtcga tccagcgcct gacacgcgag gtgtcggtgg
     7201 ccagctgcgg gtggcccatg gccgccgcct gccggttcac cattctcgcg agttcgccct
     7261 tggaccagcc ggccaggccg aacaggtcag aaaggcgggt gttgggttct ccggtcactt
     7321 caagccccca ggttctcggc tgacttgaca ctaaccccct gtcagatgcg ctgtgactat
     7381 tcgccagggt tcgccagggt ccgccagatg gtctgccacc cgcgctccgg tgtcaggtag
     7441 gaaagcgcca ccccgcccgg cagccctagg tactccccag ggtgccgaac ggccgtcggc
     7501 cgggttggcg cacgtaactt gtcggcgcac gaagggatct gtctcgccca tgtacacagc
     7561 atcgtcctcc gtgtccgccc cgccccgtcc gctccgcccg atgggcgcgg gcggcgggcc
     7621 ctatctcgct cctcacgccg gcgcaccggt gcagggtccg ggccgggccc gacgggcctc
     7681 gggaccgggc gccggaccgc tcagcggaag gatcgacctg tccgggcccc agggcgcgca
     7741 ggtacggatg gccatcgcct ccgtgcagcg catctgcccc gagttcaacc cggtccaggt
     7801 actgcgccgc agcggccgtt cggtcctgat cgtcggaacg accgggcggg ccaccgccgt
     7861 cgcgaagtgt ttactggacc actcgccggc atggaccgaa cggttccggc acgaaatagc
     7921 ggcgtaccgc gcgttcgtcc ggcaccgccc ccctgttcgg gcgccccggc tgatcgcggc
     7981 ggatccggag aactgcacgc tggtgatcga gcggatgccc ggccgggtcg ccgccctcac
     8041 ccggcacccg gcggaggcgc cgccgcgggc cgacatccgg gccgcgctcg gagccatcgc
     8101 ccgggtgaac gcctggcggc cgccgcccgg actgttcgag gcaccgctcg actacgcgtc
     8161 gcggatcgcg cgctaccacg agctcggcct gttcaccgac cgtgacctcg gtgacctgca
     8221 gaagctgctg cacggtctgg cccacgcggg cggcaagcag ggcatggggc agttctgcca
     8281 cggggacgcc ctgctctcca acatcctgct gtcgccgacc ggaccggtgc tcgtcgactg
     8341 ggagcacgcc gggtggtatc tcccggggta cgacctggcg acgctgtggg cggtgctggg
     8401 cgacgccccg gtggcgcgac gccagatcag ccagctcgcc caggcgaggg ggccggccgc
     8461 acgggacgcg ttcctggtga acctgatgct ggtgctgacc cgcgagatcc gcaattacga
     8521 gacggcggtc cagcgcacca tgcgcgaggc gcccgcgacg ggggcggggg ccgaccggcc
     8581 cggcgctctc tcctcgggcg aggagcagcg gctgctgctg cggaggctgc acgacgactg
     8641 cgccatggcg cggcgggcgg tgcgggccgc ggtcggtacc cgctgagacc ggacgacgga
     8701 gcggggatac gccccgcctg ccgagaacca cagtgaccag accactgtga agaagaagcg
     8761 cgctgcggga ccggtgccga cacaccggtc ccgcagcgcg ctgttgcgcg ttccgggccg
     8821 tatctccccg tgaccgggcg ttgaccctgt gccgccccgg ggccgcccgc gggtgaggcc
     8881 cgccacgaga cccacgtcac ctacgacctg cggtagtagg cgcgagccct cccgtacggc
     8941 gtaacgagcc gcccatatgg ctcataaatt ggcatctcac gatgaagagt agtaaaggcg
     9001 gtcattgctt cctatgtcgg cgagcgctaa ccatggatcc cggcaggcac cgagttcgag
     9061 cccgcgtcga tcgccctccg gcgaccgcgg ccccgacatc ccggttcccg ccgacgcggc
     9121 gcgaaggccg cgaagcccgt cccccatagg aagagctcac gcatgccccg catctccacc
     9181 ctgcgcatca cccgctcgca caagatcgcc accgccgtgc tcgtcgcggc cggttccgtc
     9241 agcgccatag ccgccaccgg cggcacgagc gaagcgcaga ccacggcgac ccggtcctcc
     9301 atctccgtgg agccggtcgc cgccgcaggc atccccacgg cgaaggacgc ggcggccaag
     9361 aaggccgcac aggagaccgc cgccaaggaa gccgccgcga agaaggccgt ggccgcccgc
     9421 aaggccaccg cggagaagga cgccgcagag gcgcgctccg agaagcaggc cgccaaccgc
     9481 tccaccgagc gcaaggccgt cacccccaag aagttcgcga acaacctcga cggctggatc
     9541 cgcgagtcgc tcgacatcat gaagaagaag gacatccccg gctcctacga ggggctgcac
     9601 cgcaacatca tgcgcgagtc cagcggcaac ccgaacgcgg tcaacgactg ggacatcaac
     9661 gcgcagaacg gcattccctc caagggtctc ctccaggtga tccagcccac cttcgacgcc
     9721 taccacgtca agggcacccc gaagaagctc accgacccgg tcgccaacat caccgccgcc
     9781 gccaactacg ccgcggaccg gtacggctcg atcgacaacg tcgactccgc ctactgagcg
     9841 accgacttcc gaacgaccgc cttccgagcg cgcaccaacg ccgcgattat gtgactaatc
     9901 gccgccgtgc gtgctccgta tggccgaagg gtagtgctgc gcggacacca ccggtccgcg
     9961 cgtttccccg cgcggaggct tctggaaagg cccgacgcac atggcacagc ccttctcact
    10021 gccggacttc tatgttccgt atccggcgcg gctcaaccct catgtggagg cggcacgcac
    10081 gcacacccgc gcgtgggccc gctccatggg gatgctggag ggatccggca tctgggagga
    10141 gaaggacctg gaggcgcacg actacgccct cctgtgcgcc tacacccacc ccgactgctc
    10201 ggccgaggcc ctctccctgg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttccttgaa ctgttcaagc gcacgcccga ccgggagggc ggcaagcggt atctggaccg
    10321 cctgccggcc ttcatgccga tggagcgcgg cgccccgacg ccggatccgg agaaccccgt
    10381 cgaggcgggg ctcgccgatc tgtgggcgcg cacggtcccc tcgatgtcgg acgcctggcg
    10441 ggcccggttc gcggaggcga cggagaacct cctcaacgag tccctgtggg agctcgccaa
    10501 catccacgag ggccgcatcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgcgccc tggtccgcgg gtctggtgga gtacgcggcg aacgccgagg tgcccgctcc
    10621 ggtcgccgac gcccgcccgc tgcgggtgct gcgggacgcg ttctccgacg gggtgcatct
    10681 gcgcaacgac ctcttctcct accagcgcga ggtggaggac gagggggaga acagcaacgg
    10741 cgtgctggtg ctggagaagt tcctcggctg ctccacgcag gaggccgccg aggcggtcaa
    10801 cgacctgctg acctcacggc tccagcagtt cgagaacacc gcgctgaccg aactcggccc
    10861 gctctgcgcc gagaagagcc tggacccgac gcagaccgcc gccgtgctgg cgtacgtcaa
    10921 ggggctccag gactggcagt ccggcggcca cgaatggcac atgcgctcca gccgctacat
    10981 gaacggcggc ggcgcgggcg aggccgtgcc cggcttcggc atgtccgccg cctccatcag
    11041 gttcacgttc cgctcggaga cctcgcgggc ccgcggccag agccatgtgc cgtaccagca
    11101 cgtaggtcct tccctgctgc cgggcttcga cctgccgttc gggacgacgc tgagcccgca
    11161 tctggagggg gcgcgggtcc ggatcgtcga ctgggcgcgg cggatgggca tcctggaggc
    11221 ccagccgggc gtaccgggtt cgaacatctg ggacgaggaa cggctcgtcg cgatcgacct
    11281 gccgctgtgc gcggcgggcc tggatccgga cgcgactccg gacgagctgg acctgtcctc
    11341 ggggtggctg gcctggggga cgtacgggga cgactggttc ccggtcgtgc acgggcggac
    11401 ccgggacctg gcgggggcgc ggctggccaa cgagcggctc tcgctgttca tgccgctgga
    11461 cggtgaaggg acgccggagc cggtgaacgc cctggagcgg agcctgggcg acctgtggcg
    11521 caggacggcc gcgccgatgg acgcgggcgg ccggcgtacc ttccgggcct cgatcgagtc
    11581 catgaccgag agctggctgt gggagctggc gaaccaggcg cagaaccgta tccccgaccc
    11641 ggtggactac gtggagatgc ggcgggcgac gttcggttcg gacctgacga tgagcctgtg
    11701 ccggctcggg cacggcagga aggtcccgga cgaggtctac cgcagcggtc cgatgcgttc
    11761 cctggagaac gcggcggcgg actacgcgtg cctgatgaac gatctgttct cgtaccagaa
    11821 ggagatcgag tacgagggcg aggtccacaa cggcgtcctg gtcgtgcaga acttcttcgg
    11881 cgtcgactat ccgacgggcg tggcgatcgt gcacgacctg atgaactcgc ggctgcggca
    11941 gttcctgcat gtcgccgagg tcgaactccc ggtgctgtac gaagacttcg gcctggacgc
    12001 cgaggcgcgg gagatcctgg cgggctatgt gcaggagctc aagcactgga tcgcggggat
    12061 tctgatctgg caccggggct gccggcgcta ccgcgaggag gacctgcggc gcggccacgg
    12121 cacgccctgg cacatcagcg gccccacggg gctcggcacg tcggcggcgc aggtgacccg
    12181 gttgatggcc caactggcgg gcagcccggt gtagttcgca aggtcgcggc ccgccgtccg
    12241 gaggaactgc acggcgggcc gcgaccggtg gcggaccggt cgggcagggg ctcagaggag
    12301 tacgtgccgg agcaccgcct cgaactccgc cgccgtcggc ggggtgtcgg tcagcagccc
    12361 ctggagcagc aggccgtcga tgacgccctt gagcacccgc acccggaccg ggtcgtcggt
    12421 gtagcggtgg ccgtacgccg agatggcctc cagccagtgc cgggtggggc cgcgcagctc
    12481 cgggcggcgg gccgcgagca ggtacagctc gtactccgcg agcagccgtc cgggaccctt
    12541 gacgaccttc tccatcagct ccgccagcgc ggtgacgccc tcggggccgc cgtcggcctc
    12601 ctcggccagc cggagcatgc gttgcgcgtc ctgttccatg cagcgggtga gcgcggcggt
    12661 gagcaggtcg tcgatgctcg tgaagtggta ggcggcggcg gtggcgggca ggcccgcctc
    12721 gcgggcgacc gcccggtggc tgacgccggc gactccttcc cgggcgacca cctggagcgt
    12781 ggcctcgatg agttcctcct tccgtcgctc gcccttgagc agacgtccgt cggtctgtgg
    12841 tgcgtgcacg gtgcctccgg gcgtcgtggt ggatggggcg gcgggtgtgc ttcggcgccg
    12901 tccgtcagtg tgcggccctt ccgggggcct cggcctgttc ctcggccggt ccctcggcgt
    12961 cgcgctccgc ccgctgccgg agactccgct ccagcggacg ccgggcgcac gacgccgtca
    13021 gcagagcggc cgcgcccgcg gctacggcga cgacgaagcc gccgccgggg cccaagcggt
    13081 cgacgatcgc tcccgacacc gcggcaccgg acgcgacgcc cacgctgagg ccggtgatgg
    13141 cccaggtcat gccctcggtg agtacggcgg gcggcaccgt cctctccacc agccccatca
    13201 ccacgatcat ggtaggcgcg aagaagagtc ccgggaggaa gacggcggcg gacagcgtga
    13261 cgaggtcccc gacgagcaac agggggaggg tcgtgagcgc cgtcccggcc gtgccgatga
    13321 cgagcagccg gggcagcggc gtcctgagcc ggagcgtccc gaagaccaga ccggccacgg
    13381 cggatccggc cgcgtagacc gcgaggacga ttcccgcacc ggcgggtgag ccctgctgtt
    13441 cggcgaacga gacgctcacg acgtcgacgg tgccgacgat ggcgccgccg gccacgagtg
    13501 tgagggccag caggcggagc gcgccgctgc ggatcgccga gccggtgtgc gggtgaccgt
    13561 cggccggccg ggccaccgga ggttcggtgc gcttctgcgg gacgaacagg aggacgccga
    13621 gcaccagcag caccccggcg accagcggcc cggcctcggg gaacagcgcg gtgcacaggg
    13681 ccaccgagag tgcggggccc acgacgaagg tgagttcgtc gacgaccgat tcgagcgagt
    13741 aggcggtgtg cagccggtcg gagcccttga gggcgtgggt ccagcgggcc ctcaccatcg
    13801 ccgccatgtt cggcatcgcg ccggccaccg ccgcgcagcc gaacagggtc caggcggggg
    13861 cgtcgtaccg ggcacagagc agcagcgcgc cgagcgccag cacgctcagc ccggcgacgg
    13921 gcggcagcac ccggctctgg ccccggcggt cgaccgcccg ggagatccgc ggaccgcaga
    13981 gggccatgga cagggtgaag gtggcggaga cggctccggc gaggccgtag tcaccgcgca
    14041 tctgggacac catcgcgatg atgccgatgc ccgccatgga caggggcatg cgggcgacga
    14101 acccggcggc ggtgaaagcc ctcgatccgg gcgtccggaa gaggacgccg taggggttgg
    14161 ccatgcgcgg acctccggag cagacgtacg ggcgaccctt cgcatggcgc ggtcgccgaa
    14221 cttgaacgac tgcttcaatt tgaacagtcg tttcgttttc taccctagcc ctcctcccgg
    14281 accgccgccg acccgggcgc gggaaatggc cggatcccct ccccggacaa cggaaaaggc
    14341 cgcccggacg gatccgggcg gccttgcgca gggacgtttc agccctgctg gaacagctct
    14401 gcgggcaggg gcttgagcag ggtgtacagg tcgtcggtga tcggccggtc ccagctggcg
    14461 atggtcacga ggacaccgtc gctgcgatcg aactggacgc aggcgatacg gctctcggag
    14521 agcttgacgc ggcggacgat cagcagattg tcgccctgca tgacggggac gtcctcggag
    14581 ctgacgacct cgatcggctc gtcgttctcc agggcgagga gcagttgggc cacctcgaag
    14641 gggacctggc cctcctcggt ctcgcgggcg ggcgagcctt ccgggagatt gccgatgatc
    14701 atcgccgggc cccggccgcc gtacaggtcg tagcggagga agacgccctg acagctgccg
    14761 tcgggggcgg ggagcagacc ggcgccgagg ttgccgggcc agtccccggg gtccatggcc
    14821 aggacgtcga agtccgggcc cgcgggtgtt gcggcgctac ggcggcggag gaaggacatg
    14881 ctgccatgtt acgtgtcccg gctcacgttg cggagccggg cccgggcccc gcgggaccgg
    14941 gccggccgca ttccctcagc cgggcggcgg ctccgctccg acgagccaca tggcgaagaa
    15001 ctgcgcccct ccgccgtagg cgtggccgag tgccctggtg gccccgtcga tctggtgctc
    15061 cccggccctc ccccgtacct gcagggccgc ctcggcgaag cggatcatgc cggacgcgcc
    15121 gatggggttg gtggacagca caccgcccga ggggttgacg gggaggtcgc cgtcgagttc
    15181 ggtgacgccg gcctcggtga gcttccagcc ctcgccctcg tcggcgaatc cgaggttctc
    15241 cagccacatc ggctcgtacc aggagaacgg cacgtacatc tctacggcgt cgatctcccg
    15301 gcgcgggtcg gtgatccggg cctgccggta gacgtcggcc gcgcagtcct tgcccgcctg
    15361 cggggagacg aagtccttgc ccgcgaacag ggtcggctcg ctccgcatcg ccccgccgtg
    15421 gacccaggcg ggcgggtggg gcgagcgggc cgcgccctcc cggtcggtga ggatcatggc
    15481 gcaggcgccg tcggaggagg ggcaggtctc ggagtagcgg atcgggtccc agagcatggg
    15541 ggcggcccgg accttctcca gggtgatgtc gtggtcgtgg aggtgcgcgt aggggttctt
    15601 cagcgcgttg cggcggtcct tgtacgcgac gagcgatccg accgcgtcgg gcgctccggt
    15661 gcgcctcatg tacgcccgca cgtgcggggc gaagaagccg cccgctccgg ccagcagcgg
    15721 ctgctggaag gggacgggca gggagagccc ccacatggcg ttggactcgg actgcttctc
    15781 gaaggcgagg gtgaggacgg tccggtgcac ccgggcggcg acgaggttgg cggcgaccag
    15841 cgcggtcgat ccgccgaccg agcccgccgt gtggacgcgc agcatcggct ttccgacggc
    15901 gccgagggcg tcggcgaggt agagctccgg catcatgacg ccctcgaaga agtcgggcgc
    15961 cttgccgatc acgacggcgt cgatgtcgct ccaggccagc ccggcgtcct ccagcgcccg
    16021 gacggcggcc tcgcggacca gtccggcgat ggacacgtcg tgccgggcgg cgacgtgctt
    16081 ggtctggccg atgccgacga cggcgacggg ctccttagac atgggcactc tccccttcca
    16141 ggacggcgac caggttctgt tgcaggcagg ggccggaggt ggcgtgcgcg agcgcccggt
    16201 cggactcgcc ccggtggatg cgggcggcgg cctcgccgag ccggatcagc ccggcggcca
    16261 tcacggggtt ggcggcgagc gcaccgcccg aagggttgac gcggacctcg tcgccgaggc
    16321 cgagcgcctt gcgcaggatg acctcctggg aggtgaacgg ggcgtgcaac tcggctgtgt
    16381 cgacgggccg ttcgaagact ccggcgcgct ctgcggccag ccgcgcggag gggctgtcgg
    16441 tgaggtcgcg gacgccgagg gcgtgagcct cgatccggtg gtcgatgccg cggatccagg
    16501 cggggcgcgc gcacagggcg cgggcggtgt ccccggcggc gaggaccacg gcggcggccc
    16561 cgtcgccgat gggcgggcag tcgccggtgc gcagcgggtg caccaggtag tcgcccgcgg
    16621 ggacgtcgcc ggtgagctgg gcgtgcgggt tgtcggcggc ggcggtgcgg ttgcgggcgg
    16681 cgacctcggc gagggctcct tcgtcggtgg cgcccgcgtc gatgagggcc tgcgcctgga
    16741 gggccgcgag cgctacggag tccggccaga gcggggcgag gtagtagggg tcgagctgac
    16801 gggtgaggac gtcgcgcacc cggccgggcg aggacttgcc gtaggagtag acgagcgcgg
    16861 tgtccgcctc gcctgtctgg atcttcaccc acgcctcgta cagcgcccag gccccgtcca
    16921 tctcgacgtg ggactcggag atgggcggat gagcgccgac gccgtcgagc gccatggtga
    16981 aggagaaggc ccgccccgcg aggtagtcgg cggagccgga gcaggtgaac ccgatctcgt
    17041 tcgccttgag gccggtcgcg cccaggacct cgtggaggac gggcatcagc aggtcgacct
    17101 cggacagttc gtcggtgcgc cggcggtgcg tggtctgggc gaaggcgacg atggccacgt
    17161 cccgcatcta caccagctcc ttgtacgtgt cgtagtcggc gtcgggctcg ccggtgggcc
    17221 ggtagtggtc cgggtggcgg gctccctcca cccagacggg ctcgacgcgc agccccatgc
    17281 gcacctggtc gtacgggatt ccggcgatgc gtccgtggag ggccaggtcg gcgccgtcga
    17341 gggcgatgtg ggcgtatacg tacgggactt cgatgtcgag gttcttcgct ttgatgttga
    17401 cgatgcagaa cgtggtgacc gtgccgcgcg ggccgacctc gacctgttcg gcggtggcga
    17461 ccccgcaggt ggggcaggct ccgcgcggcg ggacgtagac cttgcggcag gcggggcagc
    17521 gctcgccgac ggtgcggtgg ccttcgaggg cggtgaggta ggcgctctgg gcgcggcccg
    17581 gggtgtggac gtagtcgagg cgggccgggg tgacgatgcc ggtgacgggc tcggggaact
    17641 cccctgtgtg cggggctggt tcggaggcgc cgggctcgcc gtcgcacggc tcgaagcagg
    17701 cgatgtcggt gatggctccg gtacgcgtcg cggcccagcg gatgcggacg cgcattccgg
    17761 tgcgcacggc gtccgggcgg ggcgcgtcga gcgcgtgcag gagtgcggtg ccggccccgt
    17821 cgaggcggac gagcacccag gcgaaggggg tgccgagcgg ctggtcgcgg cctggggacg
    17881 ggttccaggc ccaggtggtg acggtgccgg tgggggcgac ctcgacaagg tcgcggatct
    17941 cgttcgcggt gacggggtcg tactccacgg gaggcacgag caccgtgccg tcctccgtgc
    18001 ggacgccgag gacggtgcgt tcgcgcagtc cggtgaggaa ggcgctctgg acgggtccga
    18061 gcgagcgggt gaaggggaat tcgaccacca gcggggcgct gaggacgtcg gacatggcaa
    18121 cagcctcctt gactcggggc tcagggtcgg gctcggcgct caggcgcgcc ggtagacggg
    18181 cggtcgcttc tcggcgaagg cccgcgcccc ctccttggcg tcctcggtgg cgaacacggg
    18241 ccagccgcgc ttgagttcgg cggccagcgc ctcgctctcg gtcagctccg caccctcgta
    18301 gaccgaggcc ttgactgcct cgacggcgag cggcccgcag gcgttgaccc gctcggcgac
    18361 gacgagggcc tcctccagtg cggttccgtc gggcacgacc ctgccgatga gcccgatggc
    18421 ggcggcctcg tcggcggtgt acgggcggcc ggtgaggagc atttcaaggg cgtgggtgcg
    18481 ggggatctga cggggcagcc ggaccgtgga gccgccgatc gggaagaggc cccggcggac
    18541 ctcgaagaga ccgaaggtgg ctcccgctcc ggcgatgcgg atgtcggtgc cctgcaggat
    18601 ctcggtgccg cccgcgacac aggggccctc cacggcggcg atcacgggtt tgcgcggccg
    18661 gtggtggcgc agcatcgcct tccagtggag gtcggggtcg gccgtcatcc gctcccggta
    18721 ccgctccccc tccatccctc cgcccgccag ggccttgagg tccattccgg cgcagaacgc
    18781 gccgccggct ccggtcagga cgacggagcg gaccgtgtcg tccgcgtcgg ccgcgagcca
    18841 gccgtcgtac agaccgacga gcatcggcag cgagagcgcg ttcctggcct gtggtctgtt
    18901 caaggtgagt accagcgtgg cgccttcgcg ccgcacggtg agatgttccg taccgcccat
    18961 gaccgactcc tgtctccaga cctggaacag gttgcaggag gagggggcgc agttcaatag
    19021 ttttctgaca gctcgtcaga ttctttcgac gccacccctt cccacttgtg ccgcccggcg
    19081 ctctaatgac ggccgagtcg ccagtcaccc ggggtcagga ggaacggtgg agtacaacct
    19141 tgccgacctg ttcgagtcgg tcgtcgacgc ggtgcccgac cgcgaggcgc tcctgtacgt
    19201 cgaccatccc ggtacgggcg cggagcggcg gctcacgtac gcggagctgg acgcggccgc
    19261 caaccggatc gcccaccatc tgatcgacgc ggggatccgg ccgggcgagc acctggggct
    19321 gcacctctac aacggggtcg agtatctcca gacggtcctg ggggccctca aggcgcggat
    19381 cgtcccggtg aacgtcaact accgttacgt cgaggaagag ttggtctatc tctaccggga
    19441 cgcggacctg gcggcgctgg tcttcgacgg cgagttcgac gagcgggtcg ctgcggccgc
    19501 cccgcaggcc ccgggtctgc gccatctggt gcgggtgggg cccgcacccg ccgctccccc
    19561 ggccgtgccg gtcgtgccgt tcaccgaagc ggagaggtcg ggcgggtccg ggcggggctt
    19621 cgcccctcgt tccgccgacg accagttcat catctacacc ggcggcacga ccggcatgcc
    19681 gaagggcgtg atgtggcgcc aggaggacct gttcttctcg ggcctgggcg gtggagcacc
    19741 gaccggcgag ccggtgaagg ccccgcagga gctggcggag cgggtcgccg cgggcgggga
    19801 cgggatcacc ttcttcccga ccccgccgct gatgcacggg acctccacgc tgaccgcgtt
    19861 catcggcttc aacttcggcc aacgcgtcgt cgtgcaccgc aagttcgtgc ccgcggaggt
    19921 gctgcggacg atcgagaagg agaaggtcac cagtgtgtcg ctggtcggcg acgcgatgct
    19981 gcgcccgctg atcgactgcc tgaacgggcc gctgcgcggg acggactgct cgtcgctgtt
    20041 ctccgtctcc agctccgggg cgatcatgtc ggactcggtg cgggcggagt tccaggcgct
    20101 cgtgccgacc gtgatgctgc tgaacaactt cggctcctcg gagtcaggtt tcaacggcac
    20161 ggcgacggcc gactccggcc cggagcgtgg cttccgggtc caggtcaacg cccgtacggc
    20221 cgtggtcgat ccggcgacgt acgagccggt ggcacccggc gagccgggcc gtatcgccca
    20281 gcgcggccat gtcccgctcg gctactacaa cgacccggcc aagaccgccg acaccttctt
    20341 ccgcaggggc gaggagcggt gggtgctgct gggcgacatg gcgaccgtgg acgcggacgg
    20401 catcgtcacc gtgctcggcc ggggctccca gtgcatcaac accggtggcg agaaggtgta
    20461 tccggaggag gtcgagcagg cgctcaagtc ccacccggac gtgtacgacg cgctcgtcgc
    20521 gggcgtaccc gacgagcgct ggggcaaccg ggtcgccgcc gtggtccaac tgcgggagaa
    20581 cgctgaggcg ttgacgctgg aggcggtgca ggcgcactgc cggacccggc tcgccggcta
    20641 caagatcccc cgcgcgctgg tactcaccga ccgaatccag cgctcgccga gcggcaaggc
    20701 ggactaccgg tgggcgaagg cggtggcggc gggggccggc cagcgctgag gggtgcgccc
    20761 ggggatccgc tcagggctga ggggcgcacc gcgcagcggc cgggcactga tcgtcaatac
    20821 cgcgtcgccg atcgtcaagg acagcgcggg tgatggtccg cagactggtg aaggtcggga
    20881 cgcccggcgc cacgggggtg cgccgtgcgc ccgaccccac gcaccggcgc accgcgccct
    20941 cctgctcgaa cggggtgacg atcaaggtga gttcgccgct gacacgcgat gatccggaac
    21001 gcatcggcgg gtactggctc gccgccagac tgggtgccgg cgggcagggc gtggtgtacg
    21061 aggcgtacga cgcttcgggc acccggtacg cactcaagac gctgcaccgg gccgctgatc
    21121 cgttcctgcg ggagcgattc acgcgggagg cggaggcggc ccgtcgggtg gccccgttct
    21181 gcacggcgag gatcgtactc gccggggtcg acggggatgt gccctacctg gtcagcgagt
    21241 acgtggcggg gccgaccctc gccgccgccg tacgggagga cgggcccccg tcccccgacg
    21301 cggtactgcg actggccacc ggggtggcga ccgcgttgtc cgcgatccat caggcgggtg
    21361 tcgtgcaccg ggacctcaag cccgggaacg tcctgctcgg ccccgacggt ccccggatca
    21421 tcgacttcgg catcgcccgc gccccggaca tgtccctcac cgccaccggc gcgatcatgg
    21481 gaaccttcgg ctacatggcc cccgaggtcc tggcgggcca acgggccacc gaggcgtccg
    21541 acgtgttcgc ctgggccgcg gtcgtgctgt acgcggcgac cggcacggag ccgttccggg
    21601 gcgagaacat cgccgaggtc gcccaccgta cgaccaccgt cgaaccggat ctgggcgctc
    21661 tgcccccgga ggtccggccg ctcatggccg ccgccctcgc caaggacccg cggcggcggc
    21721 cgacggcggc cgaactgctg ttggggctgg tcggtgcgcc cgttcgggcg gcggaccccc
    21781 gggccgcgct gatggaggcc ggcgcccgcg gggccgtcgc gcccgcgccc cgggccgacg
    21841 ccgcgcccgc cgacgccgcc acgaaggcga ccggcgcggg cggcaccgtc gtggaagcga
    21901 cgctcgggga gcgtgcggag gccgccttcg gagcgctcgc ccccgccgcc cggctcgccg
    21961 cccacgggct gctgctccgg ctctgcgtgc cgggcgccgc tcccgacggc tcccaggact
    22021 ccgtgcgcac cgctgtgccg gccgagctgc tggcgggccg gcccgagggc gaacaggaag
    22081 aggtcaccgc cgccgtccag gggctcatgg ccgccggcgt gctcgtcgcg gagacggacg
    22141 gcgccctgcg gcccgccagc gccgcgctgc tccccgcatg gcggcggctg cgctcctggg
    22201 tcgacgccga ccgg
//
