LOCUS       NZ_LIVW01000003        20609 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02115 scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_LIVW01000003
VERSION     NZ_LIVW01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02115
  ORGANISM  Streptomyces sp. CB02115
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1032236)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032236)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905645.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,651
            CDSs (total)                      :: 7,572
            Genes (coding)                    :: 7,475
            CDSs (with protein)               :: 7,475
            Genes (RNA)                       :: 79
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 34 of 97
            Pseudo Genes (incomplete)         :: 79 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 23 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:09:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 576923
            Orig. end                         :: 597532
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVW01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="7"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10609](-)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10609)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            complement(896..1213)
                     /locus_tag="AMK28_RS19860"
                     /old_locus_tag="AMK28_19605"
     CDS             complement(896..1213)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS19860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_19605"
                     /product="hypothetical protein"
                     /protein_id="WP_073742603.1"
                     /transl_table=11
                     /translation="MPSGLPVAIWHVLRTRDRIRLAPFRQPGSPAAIGGEAAAASLGPL
                     AAVQLDASARCRTPTNAQLWPVGELAAWQLVFEEQWCSSDSWQGWDAICELGARLPGFM
                     P"
     misc_feature    1389..1398
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            1532..2068
                     /locus_tag="AMK28_RS39395"
                     /old_locus_tag="AMK28_19610"
     CDS             1532..2068
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957144.1"
                     /locus_tag="AMK28_RS39395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19610"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073742604.1"
                     /transl_table=11
                     /translation="MGDLAPPWDALVGQVAEVSRRLSELEERVQSTTPEPGAEDASMEA
                     YWALPKLRERLQEVARGGVIITGSVVGPDGELVEWERSEATESVLSSDWSEAADTLGAL
                     GHPVRLRLIQALAGGRTAVTELVELEGLGTTGQVYHHLRQLVSAGWLETTGRGRYQIPP
                     SRLVPLLVVVTGARR"
     gene            complement(2718..4571)
                     /locus_tag="AMK28_RS19870"
                     /old_locus_tag="AMK28_19615"
     CDS             complement(2718..4571)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487277.1"
                     /locus_tag="AMK28_RS19870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19615"
                     /product="hypothetical protein"
                     /protein_id="WP_073742605.1"
                     /transl_table=11
                     /translation="MAEAPAAAAPVRATPNSLREVVASRDLANLTGPLGSGKSRLVAGL
                     GPVFLLDLDRPGALERLPTALADDTPAPLVVDSADDDRALASLEPLRLRPHGSGRPVLV
                     VSRRSLLARPGWAGTGVAVVETGPWPDARIGRLTAEARVTDARCRELIVRLAAGNPLIA
                     DAACRAVHAGAPPTAAGAVADAAAREIVERLSRERPAGPWQHALVRLATVWSADEELLD
                     ADPDLFDTLAGLSPVVPTELGLALTEPFRGVIELAHRWRRPAAHRGAWARALAHRKKLL
                     VDEPAADRRSRLTEGIIALADDDAVRETMFPISVTRDVIHTATPDDADTIGTLMRRWAR
                     QGGLDVRWTDRLVERWLVDDPASFQLVRDGGDRIIGLTNTQQVTERTMDCVEPLLQQHT
                     DRLLGRPRGAGGWLLGAAYCPDRGAHAHLLRGLLRQVITGGLLLTVSTPNPDYQRLLRG
                     LRFQRHGTTTDDVYRCGRKPEIFSQDFGSAALPDWTERLARTSGARGGPRPTGQEVARA
                     LAVIADPARLAESPLLSSPRPRTVAELRADLWEAVRRLADSEVREEAEAGWILQHYYLG
                     RPRTHQQLAQQLHISRATYFRRLRHGLDLVGGGLAAERSVP"
     misc_feature    complement(4449..4451)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4761..5774
                     /locus_tag="AMK28_RS19875"
                     /old_locus_tag="AMK28_19620"
     CDS             4761..5774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965568.1"
                     /locus_tag="AMK28_RS19875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19620"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_073742606.1"
                     /transl_table=11
                     /translation="MGTHTMSPLGLSSTEEVVYRFFLRNPGAAVRDARTAAPMDGEGVH
                     RAAERLRDRGLLHGSEARTWATDPGVVVARLAEEQLDAAYRTLRRLADPRPILRSLWRD
                     VPAPSFAGGGGVYAGSAIALDRLEDLGQALARIDRAAFHADAEILAAVPNRALVPLGTA
                     HTLSLGLRCLRRGVRVRTLVGSDTPTPPTGADHLRRLRSHGAEVRVAEGLSELVLVYDR
                     RTALVPVDAHDIDRGVLCIEESGPVSSLVTLFERLWAAATDLADRPASKPGTDSPTGTQ
                     RTVLLLMCTATKDEAGARAAGMSLRTYRRHVSDLLALLGACSRAQAALLARERGWV"
     gene            complement(5828..7297)
                     /locus_tag="AMK28_RS19880"
                     /old_locus_tag="AMK28_19625"
     CDS             complement(5828..7297)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453459.1"
                     /locus_tag="AMK28_RS19880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19625"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_073742607.1"
                     /transl_table=11
                     /translation="MSTVDAAVVGSGPNGLAAAVTLARAGLRVAVYEAADTIGGGLRGA
                     ALFDSEVVHDICAAVHPLAVASPFFREFDLAGRGVRMLRPDVSYAHPLDGDRVALAHHD
                     LDATCAGLGPDGPRWRRLMEPLLTHSDAMVDLLLSDLRSPRGLRAAPAVLSRVLLHGTR
                     LGSRTFRGEAAPALLAGAAAHVVGPLPSLPGAGVGLLLAQLAHGPGWPLPRGGSPRIAE
                     AMADDIRAHGGELHTGRKITDLRELAGARAVLLDIAPTALPGLAGSALPPGYTRWLSRY
                     RYGPAAGKADFLVSGPIPWSAPETGRAGTVHLGGTAAEVFRQETANARGQEGGSPFVLV
                     VDPAVTDPGREVAGRRPVWAYAHLPHGSACDPLPVIRAAIERYAPGFTDSILAQRGLSG
                     REYAAYNPNYVGGDIATGAIDLRQTVFRPVPRWDPYRTPLPGVYLCSAATPPGPGVHGM
                     CGLLAARSALRRQFGRPLPVLGPVGAGTPAA"
     gene            complement(7294..9195)
                     /locus_tag="AMK28_RS19885"
                     /old_locus_tag="AMK28_19630"
     CDS             complement(7294..9195)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378589.1"
                     /locus_tag="AMK28_RS19885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19630"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073742608.1"
                     /transl_table=11
                     /translation="MTATAAASGGAVRNLTRGQWRLLLGGTALGLLGVVCTLAQPVLLA
                     DLIRAAGDHRPVVGVVVALVVLFLLDAALSAAQGCLIGRAGENIVRDSRVLLSGKVLRA
                     DRAHLDTWRQGDLHTRLVGDTSLMKIALTQSLAQIVLNGLIVVGAVVMMAFTDIWLLLV
                     AVGCLGIAGSGSVWLARALRRAALANREDIGDFGADLQRVLAALTTVKAANAEGREQNR
                     LAESADRARVSGNRVTVLNAMFTPALNVGLQASLAAVMGIGMARVVAGSISLADFSAFT
                     MYLFYLVSPLVLVFLSIGTYLQGRAAVQRVDELDTLPQEDEHPTGTADPADGRTAALAG
                     DSATRPAPQGGHPAVEFRDVFFGYGDRQVLEGVSFTVPAQGLTAVVGASGAGKTTVFQL
                     IERFYRPRGGAILLDGRNIAHLPSAEIRGRVGYVQQDNAAMRGTLRENIVYAAPDATEA
                     EIAEAVELAGLTEVVAELPDGLDTLLGDQGIGLSGGQRQRLCVARALLQKPDVMLLDEA
                     TAHLDSDAEAALRDSLRGISGRCAVVAIAHRISTVAEADRIVVLDEGRVRAVGTHTELL
                     GNDALYRRLAATQFADRPLGGRPAPDPVPGWAQGAVPGSGPVPEPVPAALPDAGAVR"
     gene            complement(9192..10004)
                     /locus_tag="AMK28_RS19890"
                     /old_locus_tag="AMK28_19635"
     CDS             complement(9192..10004)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487274.1"
                     /locus_tag="AMK28_RS19890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19635"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_073742609.1"
                     /transl_table=11
                     /translation="MSTAAPSWNSVATAPEVQDIGYGRVFADFYDRLLPHDGSAERTAE
                     VLASWHPGGGTLELGVGTGRVAVPLARLSGEVVGVDSSPEMLRRLCETVDATGAPVIPV
                     HGDIRTYADDSRYGLVYCVCATLSLICDPAEQRTAVARAARHLAPGGTLVVETHNPGFV
                     TALHEGRARTSFFIPYAEPGTGVQTYSTLIPGGLWHASHLVHEGGRVSIGTEITRLTTA
                     EDVDSYAADAGLVLVSRQGDWAGGPFLPEGSGVHISRYRRPASGEEGS"
     gene            complement(10001..10609)
                     /locus_tag="AMK28_RS19895"
                     /old_locus_tag="AMK28_19640"
     CDS             complement(10001..10609)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965564.1"
                     /locus_tag="AMK28_RS19895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19640"
                     /product="hypothetical protein"
                     /protein_id="WP_073742610.1"
                     /sec_met_domain="cypI (E-value: 1.9e-34, bitscore: 114.6,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPRLPRATGSLLTRAFGGTDGKVRLAAGVIFLGAICCQHPHPS
                     FDRVQRLDPLASIFPNWRFFAPTPAQHDFQFYYRTLDEAGETSDWSALEVIQGRRARQF
                     VWFPERRSEKAVYDLGSEILRVLDRGFEVAVTLPSFRILRNFFREEIERSGTPDVKGFQ
                     FALVQDSGYDQAEEPEIIFLSPYTPMRETAAPARESETV"
     gene            complement(10606..12456)
                     /locus_tag="AMK28_RS19900"
                     /old_locus_tag="AMK28_19645"
     CDS             complement(10606..12456)
                     /NRPS_PKS="Domain: Abhydrolase_1 (325-439). E-value:
                     3.5e-17. Score: 54.8. Matches aSDomain:
                     nrpspksdomains_AMK28_RS19900_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453463.1"
                     /locus_tag="AMK28_RS19900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19645"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_073742611.1"
                     /sec_met_domain="PF00561 (E-value: 2e-13, bitscore: 46.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.4e-08, bitscore:
                     30.9, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGASERLAAATSLLSSIEHLARRREHRSSRLNEWAISRDAYARYG
                     RPFRKLLDLASDERTNRALHAGRVAASTALMLPGNGRWRGAATLYLGVSGALLYPAERY
                     GTDGSDQASTMVQTMTGLARLAPSSRTQDALIWYVALQGNLSYLISGWVKLLGPDWRSG
                     AALAGVMRTRTYGHEGIWKLTHRYPRASRAAVYGVLGLECLFPVLYLKGGRLTRPVLGG
                     AVLFHMANGYVMGLGRFLPAFAAMHPMVAYTSTPRSHPAVAGRDDTMPATVALLAAGGA
                     AVLGAVAVARRLRVTDTPHGGSVVTTRHGNELSVQSTLTGRSTNPVVVFVHGLGACPAY
                     FAWIVRALGSGDRQWLVYNRAGYGPSRRRADGEYTLEESVDDLVDLIDAAVPEGRQVVL
                     MGHSLGGEISRRAAVRLGSRVNSVVYVDSSHPGQLTRSAQQGATAPRIGEGLRTMAISL
                     RLGFGALMRAPEPVADLPEEVRDKVRMEFADSRVWTAAGREWKAVEQDFPSFTGPLAAL
                     DTHALVLSAQRTVDRDPDHLLMHKDLADAHSGDRTVRSVVIEGADHDGILTDPLYAAET
                     LRHLLAFLADTAGREPGARPGLLTGTEPSGRTAASEEENR"
     aSDomain        complement(11140..11481)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK28_RS19900_Abhydrolase_1.1"
                     /evalue="3.50E-17"
                     /label="AMK28_RS19900_Abhydrolase_1.1"
                     /locus_tag="AMK28_RS19900"
                     /protein_end="439"
                     /protein_start="325"
                     /score="54.8"
                     /tool="antismash"
                     /translation="PVVVFVHGLGACPAYFAWIVRALGSGDRQWLVYNRAGYGPSRRRA
                     DGEYTLEESVDDLVDLIDAAVPEGRQVVLMGHSLGGEISRRAAVRLGSRVNSVVYVDSS
                     HPGQLTRSAQ"
     gene            complement(12999..13196)
                     /locus_tag="AMK28_RS19905"
                     /old_locus_tag="AMK28_19650"
     CDS             complement(12999..13196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965562.1"
                     /locus_tag="AMK28_RS19905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19650"
                     /product="hypothetical protein"
                     /protein_id="WP_073742612.1"
                     /transl_table=11
                     /translation="MSTSPIPAALRGAGGLSESAPGQALSTFAPVAATPGIVAGAAIGV
                     ALVNAFVAGYNYTGNVELPM"
     gene            complement(13257..13451)
                     /locus_tag="AMK28_RS19910"
                     /old_locus_tag="AMK28_19655"
     CDS             complement(13257..13451)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965561.1"
                     /locus_tag="AMK28_RS19910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19655"
                     /product="hypothetical protein"
                     /protein_id="WP_073742613.1"
                     /transl_table=11
                     /translation="MSKSSAPAALTATGALTESDPGVTLPGLAPVAATPVAIVASLGAA
                     FVAGYAAGRAAGSDIELPM"
     gene            complement(13525..13698)
                     /locus_tag="AMK28_RS39685"
     CDS             complement(13525..13698)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487269.1"
                     /locus_tag="AMK28_RS39685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_198957932.1"
                     /transl_table=11
                     /translation="MSTASIPVVLSETGALSESDPGRAPLDTVPVASVTFTMSACVGIS
                     VCLIGSTIELPQ"
     gene            complement(13990..14193)
                     /locus_tag="AMK28_RS19915"
                     /old_locus_tag="AMK28_19660"
     CDS             complement(13990..14193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487268.1"
                     /locus_tag="AMK28_RS19915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19660"
                     /product="hypothetical protein"
                     /protein_id="WP_073742614.1"
                     /transl_table=11
                     /translation="MPEFRQPGWTRGIAPLQEGAGGQVFGGASPVAATPVVVAGAGAVV
                     VAFAAGVAARTLANGGNIELPM"
     misc_feature    14272..14285
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    14285..14300
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(14727..14738)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            14814..15284
                     /locus_tag="AMK28_RS19925"
                     /old_locus_tag="AMK28_19665"
     CDS             14814..15284
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070686.1"
                     /locus_tag="AMK28_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19665"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073742615.1"
                     /transl_table=11
                     /translation="MPVNLRPLDAEHFPAWLERSRAEYAKELVALGQTSEDAYRQADET
                     MALSFPSGTPTPDHAVFDVVDDAGVAVGYLWIGPDRSDDAGAWWVWDIAIDADKRGRGL
                     GRTAMLLGEEYARARGARTLGLSVAGFNTGARGLYESLGYETTSVKMRKKLG"
     gene            complement(15288..>15544)
                     /locus_tag="AMK28_RS40640"
                     /old_locus_tag="AMK28_19670"
                     /pseudo=""
     CDS             complement(15288..>15544)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969235.1"
                     /locus_tag="AMK28_RS40640"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AMK28_19670"
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="QWAERGGKHKDPDREPRRRPRATYNRYGGVRHLFAALDLVRDRLY
                     GHIKPVKRNRAA"
     gene            15522..15815
                     /locus_tag="AMK28_RS39690"
     CDS             15522..15815
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS39690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_198957944.1"
                     /transl_table=11
                     /translation="MPPRSAHCPQDRPDIAEVVRRCRALIETQGLQVAQARRRLTTYTT
                     APTHVLDGLLAVGRMSGPGVRMVPGTAGAALSARFSALRAPRSLPGSVVMNR"
     tRNA            complement(15926..15999)
                     /anticodon=(pos:complement(592886..592888),aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AMK28_RS19935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="AMK28_19675"
                     /product="tRNA-Pro"
     gene            complement(15926..15999)
                     /locus_tag="AMK28_RS19935"
                     /old_locus_tag="AMK28_19675"
     gene            complement(16049..18704)
                     /locus_tag="AMK28_RS19940"
                     /old_locus_tag="AMK28_19680"
                     /pseudo=""
     CDS             complement(16049..18704)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513194.1"
                     /locus_tag="AMK28_RS19940"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19680"
                     /product="AAA family ATPase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKPSRPLYEREPELAAAAEAVDALCGAQAVGGLLVFSGEAGIGKT
                     ALLAEIRRMAADRCTVWSARGGETVTSVPFHVVRQLLQPALDQFPPDETRALFGDWYET
                     TAPALGLAEPSGPQPDPQGVRDGLDFVVGRLASRLSHRPLLLIVDDAHWADGESLAWLA
                     SFTARLGELPVLVVQAHRPQELAERDANYIADREAERGFGSKGTVTRVALRALTPDATA
                     VLVRAGLGDHADDPFCREVWAVTGGNPYEAVELVAKVQDRELPPVEESAGELRELGASA
                     RGSGLVARLERLGTNANRFAWAAAVLGTDISQELAATLAGMSSAEAADCTARLRDARIV
                     SGFDPLEFVHPLIATAVYRSIPPATRTAMHGRAAWAITRAGLGAAAASRHLLEVHPDDD
                     QELVAQLREAAGQHLAVGAPEAARRCLERAIEEPPRPKDRAVLLYELGCATLLSSPPTT
                     VQHLRAALDMPGLDDGLRVDATFRLAAALAHNNQLKDAALSLAAEAARTAPGPGLMRLQ
                     AAHFMWEGMQAAEDDGPARSRRLTRNADHLKGRDNAERALLTLRAFDAMVRR"
     misc_feature    complement(18273..18275)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18815..19294
                     /locus_tag="AMK28_RS19945"
                     /old_locus_tag="AMK28_19685"
     CDS             18815..19294
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457262.1"
                     /locus_tag="AMK28_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19685"
                     /product="DUF309 domain-containing protein"
                     /protein_id="WP_073742616.1"
                     /transl_table=11
                     /translation="MNETRRDRDAEGRARNARPRDGLGRPLPYGTPGVERQPEGVVRTP
                     AETLREAQRLLDAGMPFHAHEVFEDAWKSGPEDERELWRGLAQLAVGLTHSARGNTAGG
                     ARLLRRGAGALAPFTGSGPHGIAVSGLSDWARELADRVESGPTVDAAAEAPRLRA"
     gene            19385..19885
                     /locus_tag="AMK28_RS19950"
                     /old_locus_tag="AMK28_19690"
     CDS             19385..19885
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129014.1"
                     /locus_tag="AMK28_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_19690"
                     /product="hypothetical protein"
                     /protein_id="WP_073742617.1"
                     /transl_table=11
                     /translation="MSTSDQDQHRDQREDGLNDEEPDRDQERGRGADTSIAETAAETKT
                     AAAETVAAETVAAAETDGVDVSGGEDRGDGQNDQDGKRLTPRQARQLRIALSSVGMAAM
                     ALVLGLRIASRSSVLVVGVYGLALILCGVVIELSRNGRTRLASWLLGAGLLAAVGADWL
                     LLP"
ORIGIN
        1 gcgaaggccc ccgccggtac gggctcggaa ggctccgcca aggccccctc ggcagagacc
       61 gcgccccagt cgcagcccca gacgacgccc aaggctccca ccgtggtgta cagcggggtg
      121 tccggccacg agtgccccac ccagcgcttc cagcgggacg gctactacag cgacggcaag
      181 gagggctggg ccacccacag cggcggcttc ggcggctacg gctgcgcggg caagtacctc
      241 tccatgccga tgtccggcag ctcctccaag gactccggcg gctcggcgac ctggctgttc
      301 gacctgcccg cctccgccaa gaagtgcagc atctccgtcc atgtgcccgg cagttcggac
      361 atcgtgcggg tcggtggcga cccgagctac tacacggtct acgaccggtt cctgcccagg
      421 accaacaacc tggtgggctc cttctacgtc aaccagcagg accgccgagg cacctggtac
      481 aacgtgccgg gcaccttcgc cgtcgacgcc aagaagctct ccgtccgcat ccacgaccgg
      541 ggccgggaca gcaagtacga gcaccacgcg atttcgacga tcaaggcgac ctgcaccggc
      601 tgagcggcgg gcgcggaccg cgcggagccg ccggtcgtgc ggccgtccgc cggctccgtc
      661 ccggcctcga ccccggcccc gtacgtgacc cggagcgcgt cacgtacggg gccggggcgc
      721 gtcggacggg tgacggcaag gaacagccac agccgaccgg gagccgacgc cgagccggac
      781 cgcttcgagg agagccgccc ctcgtcgccc accccaactg gtcccatggg gcgtgtccgt
      841 gacacgcacg tccaagggtc gccgccgggt cgagaggccg gctcgccaag gcctgtcacg
      901 gcatgaaacc tggcagcctt gcgccgagct cgcagatggc gtcccaccct tgccaggaat
      961 cactgctgca ccactgctcc tcaaagacca gctgccaggc agccagttca cccaccggcc
     1021 acaactgcgc gttcgtgggt gtccggcatc gcgccgaggc gtcgagctgg accgcggcca
     1081 agggacccag ggaggccgct gccgcttcgc caccgatcgc tgccgggctg ccgggctgcc
     1141 ggaaaggcgc gaggcggatg cggtcccttg ttcgcaggac gtgccatatc gccaccggca
     1201 ggccgctcgg catccatgtt cccgcgcgaa tgcccgccct gtcccctggc tgcctgttcc
     1261 tgtgcctggc cctgcccacg gccctcaagg tgccctagaa cgccggggcc cggaacccca
     1321 gccgtctccc gagcgggcgt gaaggtccac cgcaggaacg cttcccctgc tgccgccgtc
     1381 cggacctcga aggcggccga ttcgctgacg gtcataacga gcaacccaac gcctgccccg
     1441 gcatcactgt cgccgacccg ggtcagacgg actgcagttt cacttcggtg ggcgagggcc
     1501 gtgcgcgcgc gtccgacgat aggctggccg aatgggtgat cttgcgccgc cgtgggacgc
     1561 gttggttggg caggtcgccg aggtttctcg gcgactctcc gagcttgagg agcgagtgca
     1621 gagcaccacg cctgagccag gtgccgaaga cgcgtcgatg gaagcttact gggcattgcc
     1681 aaaacttcgg gagcgcctgc aggaagtagc gcgaggggga gtgatcatta ccgggtccgt
     1741 ggtcggtccg gacggtgagc ttgtggagtg ggaacggtcc gaagccacgg agtcggtgtt
     1801 gagttctgac tggtctgagg cggccgacac cctgggagct ttggggcacc ccgtgcgttt
     1861 gcgcctgatc caggccttgg ctggaggacg gactgcggtt accgaactcg tggagctgga
     1921 ggggctcggt acgaccgggc aggtctatca ccatctacga caactcgttt ccgccggctg
     1981 gctggagacg accggacgtg ggcgatatca gattcctccg tcccggctcg ttccgctgct
     2041 ggtcgtggtc accggagctc gccgctgacc gggtcgttct gcaaccctcg gtcggcgcat
     2101 acctcgccca tccaggcaga gcaccgggcg agacggatgg ccccgaataa agcgcccgcc
     2161 gtggcgcggc ctctctcgca cagcatcgct tctgggaact gccctacaac cagacccctt
     2221 tcgcgttcag gacacaaaca cccaagccct tctccgcctc gcccgccacc gcatcaacgt
     2281 cccgttcgcc gagctccgcg acggcacctt ccacgaaccc cgaaccccca ccgtcaccct
     2341 cgcagcatga aactgaccga ccaccccaga atcgaccgca ccacctcgac gaacgacgcg
     2401 gcggtgcccc caggatcacc gcccacgaga cgaacgcgag gcacgtcggc gacttcaccc
     2461 gctctccgcc ggagagcggg tagttcctct gcctggccat cgtcatcgac ctcgcctcac
     2521 ggcatctgac cggccggccg atcgcggatc acctgcgcac cgatctcgtc atcgacgccc
     2581 tcaccgcccg cggccacacc ttcgtgacgg tgccgcagct cctggtcccg gcagggctga
     2641 gccgggcgag gtctgccgct gaggcacccg gccccgccgc tccccaccac ccgccgccgc
     2701 cgtcctcccg gcgcccctca tgggacgctc cgttccgccg cgagcccgcc gcccaccagg
     2761 tccaggccgt gccggagccg ccggaagtag gtggcgcggc tgatgtggag ctgctgggcg
     2821 agctgctgat gggtccgcgg ccgtccgagg tagtagtgct ggagaatcca cccggcctcg
     2881 gcctcctcgc gcacctcgct gtccgccagc cgtcgcaccg cctcccacag gtccgcgcgc
     2941 agttccgcca ccgtccgggg gcgcggcgag gagagcagcg ggctctcggc cagccgggcc
     3001 gggtcggcga tgacggcgag ggcacgggcc acctcctggc cggtcggacg cgggccgccg
     3061 cgcgcccccg aggtgcgggc gagccgctcc gtccagtcgg gcagcgcggc ggagccgaag
     3121 tcctggctga agatctcggg cttgcgcccg cagcggtaga cgtcgtcggt ggtagtgccg
     3181 tgacgctgga agcgcagccc gcgcagcagc cgctggtagt ccgggttcgg ggtggacacc
     3241 gtcagcagca ggccgcccgt gatgacctgg cgcagcaggc cgcgcagcag gtgcgcatgg
     3301 gcaccccggt cggggcagta ggccgcgccg agcagccatc ccccggcgcc gcgcgggcgg
     3361 ccgagcagcc ggtccgtgtg ctgctggagc agaggttcca cacagtccat ggtgcgttcg
     3421 gtgacctgct gggtgtttgt caggccgatg atccggtcgc cgccgtcccg gaccaactgg
     3481 aaactggcgg ggtcgtcgac gagccagcgt tccaccaggc ggtcggtcca gcgcacgtcc
     3541 agcccgccct gccgggccca ccggcgcatc agggtgccga tggtgtcggc gtcgtccggg
     3601 gtagcggtgt ggatcacgtc ccgggtcacg ctgatgggga acatggtctc gcggacggcg
     3661 tcgtcgtcgg ccagagcgat gatcccctcg gtgagacggc tacggcggtc ggcggcgggt
     3721 tcgtcgacca gcagcttctt gcggtgggcg agcgcgcggg cccacgcgcc gcggtgggcg
     3781 gcgggccgac gccagcgatg ggccagttcg atcaccccgc ggaagggctc ggtgagggcc
     3841 aacccgagtt cggtggggac gaccgggctg agccccgcca gggtgtcgaa caggtccggg
     3901 tcggcgtcga gcagttcctc gtccgccgac cacacggtgg ccagccggac cagggcgtgc
     3961 tgccacggcc cggcgggccg ctcccgggag agccgctcca cgatctcccg ggcggcggcg
     4021 tcggccaccg ccccggccgc ggtcggcggc gcacccgcgt ggacggcccg gcaggccgcg
     4081 tcggcgatca gcgggttgcc cgcggcgagc cggacgatca gttcccggca ccgcgcgtcg
     4141 gtcacccgcg cttccgccgt cagacgcccg atccgcgcgt ccggccacgg gccggtctcc
     4201 acgaccgcga cccccgtgcc ggcccatccc ggccgggcca gcagggagcg cctgctgacc
     4261 acgaggacgg gccggccgct gccgtgcggg cgcagccgca gcggctccag cgaggccagg
     4321 gcgcggtcgt cgtcggcgct gtccacgacc agcggggccg gggtgtcatc ggcgagcgcg
     4381 gtcggcagcc gctccagggc gccgggccgg tcgaggtcaa ggaggaagac gggcccgagt
     4441 ccggcgacta accgggactt cccgctgccg agcgggccgg tgagattggc cagatcacgg
     4501 cttgccacca cctcccgcag ggagttcggc gtggctcgta ccggcgctgc ggctgcgggt
     4561 gcctcggcca tcggacctcc aggatcactt cggtgcacgg ccccctgtca tagcgatcag
     4621 agcccgttca ttcaagtggt cacacatccg gaacttccct ggtgccggca gggcgtgaga
     4681 cttcgctgag acctcacgcc ccgtctcccc gggcagactt gggctccgtc gtcccgccgg
     4741 acatgttcaa gggaagggcc atggggaccc atacgatgtc gccactcggt ctgagcagca
     4801 ccgaagaagt ggtgtaccgg tttttcctgc ggaatccggg tgccgccgtc cgtgacgcgc
     4861 gcaccgccgc gccgatggac ggggagggcg tgcaccgggc cgcggagcgg ctgcgcgacc
     4921 gggggctgct gcacgggagc gaggcgcgga cctgggccac ggacccgggg gtcgtggtgg
     4981 cgcggctggc ggaggagcag ttggacgccg cctaccggac gctgcgccgc ctcgccgacc
     5041 cgcggccgat cctgcgctcc ctgtggcggg acgtgcccgc cccctccttc gcgggcggcg
     5101 ggggcgtcta cgcgggttcc gcgatcgccc tggaccgcct ggaggacctg gggcaggccc
     5161 tcgcccggat cgaccgggcg gccttccacg ccgacgccga gatcctggcc gcggtgccca
     5221 accgggccct ggtaccgctg ggcacggccc acactctctc actcggcctg cgctgcctgc
     5281 ggcgcggtgt ccgggtgcgg accctggtgg ggagcgatac tccgacgccc ccgaccggcg
     5341 cggaccatct caggcggctg cgctcccacg gcgcggaggt cagggtcgcg gaggggctct
     5401 cggaactggt gctggtctac gaccggcgca ccgcgctggt ccccgtcgac gcgcacgaca
     5461 tcgaccgggg cgtcctgtgc atcgaggaga gcggcccggt gagcagtctc gtcaccctct
     5521 tcgaaaggtt gtgggcggcg gcgacggacc tcgccgaccg tcccgcgtcg aagccgggca
     5581 ccgacagccc caccgggacc cagcgtacgg tgctgctcct catgtgcacc gccaccaagg
     5641 acgaggcggg cgcccgggcg gcgggcatgt cgctgcgcac ctaccggcgc catgtctccg
     5701 atctgctggc tctgctgggc gcgtgcagca gggcccaggc ggcgctgctg gcccgcgaac
     5761 gcggctgggt gtgatcccgg cccgcggacc ggggccggtg tggcgccggc cgggccgggc
     5821 cgggtcgtca tgcggccggg gttcccgcgc cgaccgggcc gagcacgggc agcggccgtc
     5881 cgaactggcg gcgcagcgct gaccgggcag cgagtaggcc gcacatgccg tgcaccccgg
     5941 gtccgggcgg ggtggccgcc gagcagaggt agacgccggg cagcggggtc cggtaggggt
     6001 cccaccgggg gacgggccgg aacacggtct gccgcaggtc gatcgccccg gtcgcgatgt
     6061 caccgcctac gtagttgggg ttgtaggcgg cgtattcccg cccggacaga ccgcgttggg
     6121 cgaggatgga gtcggtgaag cccggcgcgt accgctcgat ggccgcgcgg atcacgggca
     6181 gcgggtcgca cgcgctgccg tgcggcagat gggcgtacgc ccacaccggg cggcgcccgg
     6241 caacctcgcg tcccgggtcg gtcacggccg ggtcgacgac caggacgaac ggtgaacccc
     6301 cttcctggcc gcgggcgttg gccgtctcct ggcggaagac ctcggccgcc gtgccgccca
     6361 ggtgcacggt gcccgcgcgg ccggtctccg gagccgacca ggggatcggt ccggagacca
     6421 ggaagtccgc cttgcccgcg gccgggccgt accggtaccg ggacagccac cgggtgtagc
     6481 cgggtggcag ggcgctcccg gcgaggccgg gcagcgcggt cggcgcgatg tccagcagaa
     6541 cggcccgcgc ccccgccagt tcccgcaggt cggtgatctt ccgcccggta tgcagttccc
     6601 ctccgtgcgc ccggatgtcg tcggccatgg cctcggcgat gcgcgggctg ccgccgcgcg
     6661 gcagcggcca gccggggcca tgggccaact gggccagcag cagcccgacc ccggcgccgg
     6721 gcagcgaggg cagcgggccg acgacgtgcg cggcggcccc ggcgagcagt gcgggcgccg
     6781 cctcgccgcg gaaagtgcgg gagccgagcc gggtcccgtg gagcaggacc cggctcagta
     6841 cggcgggtgc ggcgcgcagc ccgcgcgggc tgcgcagatc ggacagcagc aggtcgacca
     6901 tggcgtcgct gtgtgtcagc agcggttcca tcagccgccg ccagcgcggc ccgtccgggc
     6961 cgaggcccgc gcaggtggcg tccaggtcgt ggtgggcgag ggccacccgg tcgccgtcca
     7021 gcggatgggc gtagctgacg tcgggccgca gcatccgcac gccccgtccc gcgaggtcga
     7081 actcccggaa gaacggcgag gccaccgcca gggggtggac ggccgcgcag atgtcgtgca
     7141 ccacctcgga gtcgaacagc gcggcgccgc gcagtccccc gccgatcgtg tcggcggcct
     7201 cgtacacggc cacccgcagg ccggcgcggg ccagggtgac ggcggcggcc agcccgttcg
     7261 gcccgctgcc cacgaccgcc gcgtccacgg tgctcaccgg acggctcccg cgtccggcag
     7321 ggcggccggg accggctcgg gcaccggacc ggagcccggc accgcgccct gggcccagcc
     7381 cggcacgggg tccggcgcgg ggcgtccgcc gaggggacgg tcggcgaact gggtggcggc
     7441 cagacgccgg tagagggcgt cgttgccgag gagttcggtg tgcgtgccca cggcgcgcac
     7501 ccggccctcg tccaggacca cgatccggtc ggcctcggcc accgtggaga tccggtgggc
     7561 gatggcgacg acggcgcacc gcccggagat gccgcgcagg ctgtcgcgca gcgccgcctc
     7621 ggcgtcggag tccaggtgcg cggtggcctc gtcgagcagc atcacgtcgg gcttctgcag
     7681 caacgccctt gccacgcaga gccgttgccg ctggccgccg gagagtccga tgccctggtc
     7741 gccgagcagg gtgtcgaggc cgtccggcag ctccgccacc acctcggtga gaccggcgag
     7801 ttcgacggcc tcggcgatct ccgcctcggt ggcgtcgggc gcggcgtaca cgatgttctc
     7861 gcggagggtt ccgcgcatcg cggcgttgtc ctgctggacg tagccgaccc ggccgcggat
     7921 ctcggcggac gggaggtggg cgatgttcct gccgtcgagg aggatcgcgc cgccccgggg
     7981 ccggtagaag cgctcgatga gctggaagac ggtggtcttg cccgcgccgg aggcacccac
     8041 cacggcggtg agcccttggg cggggacggt gaacgacacg ccttccagca cctgccggtc
     8101 gccgtagccg aagaagacat cgcggaactc cactgcgggg tggccgccct gcggagccgg
     8161 acgggtggcc gagtcgccgg cgagggcggc ggtccggccg tcggccgggt ccgcggtgcc
     8221 ggtcgggtgc tcgtcctcct gcggcagggt gtcgagttcg tccacgcgct ggacggccgc
     8281 ccggccctgg aggtaggtgc cgatcgagag gaagaccagg accagcggcg acacaaggta
     8341 gaacagatac atcgtgaaag ccgagaagtc ggccaggctg atggagccgg ctacgacgcg
     8401 ggccatgccg atgcccatca cggcggcgag cgacgcctgg agaccgacat tcagcgcggg
     8461 tgtgaacatg gcgttcagca cggtgacccg gttgccggag acgcgggcgc ggtcggcgga
     8521 ctccgccagg cggttctgct cacggccctc ggcgttggcg gccttcaccg tcgtcagggc
     8581 ggcgagcacg cgctgcaggt cggcgccgaa gtcgccgatg tcctcccggt tggccagggc
     8641 ggcccggcgc agcgcgcggg ccagccacac cgacccggac ccggcgatac cgaggcatcc
     8701 gacggcgacc agaagcagcc agatatcggt gaacgccatc atcacgacgg cgccgaccac
     8761 gatcagcccg ttgaggacga tctgggcgag gctctgggtg agcgcgatct tcatcaggga
     8821 ggtgtcgccg accagccggg tgtgcaggtc gccctggcgc caggtgtcga ggtgcgcgcg
     8881 gtcggcccgg agcaccttgc ccgagagcag gacccgggag tcgcggacga tgttctcccc
     8941 cgccctgccg atgagacagc cctgggcggc ggatagcgcg gcgtccagca ggaacagcac
     9001 taccagcgct acgacgaccc cgaccaccgg gcggtggtcc ccggcggccc tgatcaggtc
     9061 ggccagcagc accggctgcg ccagggtgca caccacgccc agcagtccga gggcggtgcc
     9121 cccgagcagc aaccgccact gcccgcgcgt caggttccgc acggcgccgc cggacgccgc
     9181 cgcggtggcc gtcatgaccc ttcctcaccg gaggcggggc ggcggtagcg actgatgtgg
     9241 acgccgctcc cctcgggcag gaacgggccg cccgcccagt cgccctgccg ggacaccagg
     9301 acgagaccgg cgtcggcggc gtaggagtcg acgtcctcgg cggtggtgag ccgggtgatc
     9361 tcggtgccga tgctcacccg gccgccctcg tgcaccaggt gcgaggcgtg ccagagcccg
     9421 ccggggatca gggtggagta ggtctgcacg ccggtgcccg gttcggcgta gggaatgaag
     9481 aaggaggtgc gggcgcgccc ctcgtgcagg gcggtcacga agccggggtt gtgggtctcc
     9541 acgacgaggg tgccgccggg tgccaggtgc cgggccgccc gcgcgacggc cgtccgctgc
     9601 tccgccgggt cgcagatcag tgagagggtg gcgcagacgc agtagaccaa cccgtaacgg
     9661 gagtcgtcgg cgtaggtgcg gatgtcgccg tgcaccggga tgaccggggc gccggtggcg
     9721 tcgacggttt cgcacagccg ccggagcatc tccggcgagg agtccacacc gacgacctcg
     9781 ccggagagcc gggccagcgg cacggcgacg cgtccggtgc ccacgccgag ttcgagggtg
     9841 ccgccgccgg ggtgccagga ggcgaggacc tcggcggtgc gttcggcgga gccgtcgtgg
     9901 ggcagcaggc ggtcgtagaa gtcggcgaac acccttccgt agccgatgtc ctggacctcg
     9961 ggggcggtgg ccacggagtt ccaggagggg gcggcggtgc tcatacggtc tcgctttctc
    10021 gcgccggtgc cgcagtctcg cgcatcggtg tgtaggggga gaggaagatg atctcgggct
    10081 cctcggcctg gtcgtagccc gagtcctgga ccagggcgaa ctggaagccc ttgacgtccg
    10141 gcgtgccgga acgctcgatc tcctcgcgga agaagttgcg caggatacgg aaggagggca
    10201 gggtcacggc gacctcgaac ccgcggtcga ggacgcgcag gatctcgctg cccaagtcgt
    10261 acaccgcctt ctcgctgcgc cgttcgggga accagacgaa ctggcgggcg cggcggccct
    10321 ggatgacctc cagcgcggac cagtcggagg tctcgcccgc ctcgtcgagg gtgcggtagt
    10381 agaactggaa gtcgtgctgg gcaggagtcg gggcgaagaa gcgccagttg gggaagatgc
    10441 tcgcgagcgg gtcgagccgc tggacccggt cgaaggacgg gtgcgggtgc tggcagcaga
    10501 tggcgccgag gaagatgacg ccggccgcga ggcggacctt gccgtccgtg ccgccgaagg
    10561 cgcgggtcaa cagcgagccc gtggcgcgcg ggagacgggg gttgctcatc ggttctcctc
    10621 ctcagacgcg gcggtccggc cggacggctc cgtcccggtc aggagtccgg gccgggcccc
    10681 cggttcccgc ccggcggtgt cggccaggaa ggccagcagg tggcggagcg tctcggcggc
    10741 gtacaggggg tccgtgagga tgccgtcgtg gtcggcgccc tcgatgacga cgcttcggac
    10801 ggtccggtcc ccgctgtggg cgtcggcgag gtccttgtgc atcagcaggt ggtcggggtc
    10861 gcggtccacg gtccgctggg cggagagcac cagggcgtgc gtgtccaggg cagcgagtgg
    10921 cccggtgaag gaggggaagt cctgctcgac ggccttccat tcacgccccg cggcggtcca
    10981 cacccgggag tccgcgaatt ccatcctgac cttgtcccgc acctcttcgg gcaggtcggc
    11041 gaccggctcg ggcgcccgca tcaacgcccc gaaccccaac cgcagactga tggccatggt
    11101 gcgcaggccc tccccgatcc gcggcgcggt cgcgccctgc tgcgccgacc gggtgagctg
    11161 gccggggtgc gaactgtcca cgtagacgac ggagttcacc cgggagccca gcctgaccgc
    11221 cgcgcggcgg gagatctcgc cgcccaggga gtggcccatc agcaccacct ggcgcccctc
    11281 ggggaccgcc gcgtcgatca ggtccaccag gtcgtcgacc gactcctcca gcgtgtactc
    11341 tccgtccgcg cggcgccggc tggggccgta accggccctg ttgtacacca accactgccg
    11401 gtccccgctg ccgagagcgc ggacgatcca ggcgaagtac gcggggcagg cgcccagtcc
    11461 gtggacgaag accaccaccg ggtttgtact ccggcccgtg agggtgctct gcacgctcag
    11521 ttcgttgccg tgccgcgtag tgacgacgga gccgccgtgc ggggtgtcgg tgacgcgcag
    11581 ccgccgggcc accgcgaccg cccccagtac ggccgcgcca cccgccgcca gcagggccac
    11641 cgtggccggc atggtgtcgt cgcggcccgc caccgcgggg tggctgcgcg gcgtgctggt
    11701 gtaggcgacc atcgggtgca tcgcggcgaa ggccgggagg aacctgccga ggcccatgac
    11761 gtagccgttg gccatgtgga agaggacggc gccgcccagc accgggcggg tcagccggcc
    11821 acccttcaga tagagcaccg ggaacaggca ctccagaccc agcacaccgt agacggcggc
    11881 gcggctcgcc cgggggtagc gatgggtcag cttccagatc ccctcgtgcc cgtacgtcct
    11941 ggtccgcatc acccccgcca gcgcggcccc cgaccgccag tcgggaccca gcagcttgac
    12001 ccagccggag atcaggtagg acaggttccc ctggagcgcc acgtaccaga tcagggcgtc
    12061 ctgggtgcgg gacgaggggg cgagtcttgc cagcccggtc atggtctgca ccatggtgga
    12121 cgcctggtcg gagccgtcgg tgccgtagcg ctcggccggg tagagcaacg ccccgctgac
    12181 gccgaggtag agggtggcgg ccccgcgcca cctgccgttg ccgggcagca tgagagccgt
    12241 gctcgcggcc acccgcccgg cgtgcagcgc ccggttggtc cgctcgtcgg aggccaggtc
    12301 cagcagcttg cggaagggcc tgccgtaacg ggcgtacgcg tcgcgggaga tggcccattc
    12361 gttcagccgg ctcgaccggt gctcccggcg gcgcgcgagg tgctcgatgc tggacagcag
    12421 ggacgtcgcc gccgccagcc gctcggaggc gcccatggct tgctcgcggg agaggggggc
    12481 cgggccttgc agggcggaca ggaccccgcg cagcgtcggc cgctgtctgc ggggtccact
    12541 cggtcgggtg gggcgtgagg gcatggacgg gccttccgtg ctggggacga acgaggcggg
    12601 agggcgacgg ggtgacaagg cggaggggtg gcgggcggtt cccgagcccc ggtacggggt
    12661 cccacgggcc ggatgggccg ggcaggatga tgtccggggg cgtaccgggt tcgtgcggga
    12721 cgggttcctg cagggccggg ctcgtgccgg ggccgggccg tgcgtccggg cgtggtggtg
    12781 gcatgggcgg gcgaccgccc tggaggcgct cgtccccacg tcacccacgc accgtcgctt
    12841 ccggcaggcc ccggcacggc ggccgcggct ccccgtgccg gggccggggg cgacggacct
    12901 accgctcggc gcccgtgccg cggaggcggc tcaccgcccc ctggggcgtc gccgcgttct
    12961 ggaggctccc ccaccgggga cgggacggct taccgggctc acatcgggag ttcgacgttg
    13021 ccggtgtagt tgtaaccggc gacgaaggcg ttcaccaggg cgacgccgat ggccgcgccg
    13081 gccacgatcc cgggggtcgc ggcgaccggc gcgaaggtcg acagcgcctg gccgggcgcg
    13141 gactcggaca gaccaccggc gccgcgcagg gcggccggta tcggagacgt gctcacaggg
    13201 ttgttctcct tactggagtg atggaacgga acggtccggt gctgcgggaa acacgactac
    13261 atcgggagtt cgatgtcact cccggccgcg cggccggccg cgtaaccggc gacgaacgcg
    13321 gctcccaggc tggccacgat ggccaccggg gttgcggcga ccggcgcgag gcccggcagc
    13381 gtcacgccgg ggtcggactc ggtcagggca ccggtcgcgg tcagggcggc cggagcagag
    13441 gacttactca cgaaactctc ctactggtga ggtggcgggt actggtgagg tgccgggcca
    13501 ccagcaacgg gtggcccgtc gggcctactg cgggagctct atggtgcttc cgatgaggca
    13561 gaccgagatg ccgacgcagg ccgacatggt gaacgtgacg gaggcgaccg gaacggtgtc
    13621 cagcggcgcc cggccggggt cggactcgga cagggcaccg gtctcggaca gaacgaccgg
    13681 tatcgaagcg gtactcaagg acttctcctc gctggtgggc ggccggtggg gtgacgtcat
    13741 gggcgagcgg cgcggacggg acggacccac aggtccgggc gccgagtgcc gtcggccgcg
    13801 tacccggccg tcggacggcc ttcgcgtcgt ggagccgtca tgggtacggc aaccgacgcc
    13861 ggcggccccc tgacgggatt cagctccgac gggagggggc gggacggacc gccccggtgg
    13921 gagcggaggg tgtccgggcc acgcgccggg cgtcgtcccc ggccgagtcg ggtggcgggg
    13981 tgccaccgcc tacatcggga gctcgatgtt gccgccattg gccaacgtgc gggcggctac
    14041 gccggccgcg aaggcgacca ccacggcacc cgcgccggcc acgacaaccg gggtcgcggc
    14101 gaccggggac gcgcccccga acacctgccc accggcgccc tcctggagcg gggcgatgcc
    14161 cctggtccaa ccgggctgtc tgaattcggg catgtttctc cttcatgggt gggccgtcac
    14221 cggggctcct catccaggcg cgcgcaagcg cacccgggac ccggccccgc gtgaacagac
    14281 gttctgtgat gcgctccaca cgatgccgag agcccggagg aaagggaaga ccactccgct
    14341 ggcatgagga tgcggactcc gaagcaacat cctgcaggtt cgggcacagg ggtatgcggc
    14401 gcgtgccgat tccgatagtc cggcctggaa cgcgtgaggc ctttccaacc tcacgctgat
    14461 gcgtggtgaa gcgcgaggac tgccttcacc aggtcggtga tgcggttggt gctgcagcgg
    14521 agcttccgca ggagccgcca gcctttgttc gagtgagcga cctccacggg cgccaacctt
    14581 ttgtgatgcc cgactgcttc tccgagggac acccggcttg ggctttcggg ccgggcagaa
    14641 cggaccggac ttggcggaga agacggaacc gatcgcctcg gcggtgccga gaaggaccaa
    14701 gccgcccacc gggacgtgcc gcgtcagtca acgtttgccc tgttggtgat gcgccgtgac
    14761 gcctgagcgg gagtggcacc gctcaggcgt cggcggtgtg ggaggctggg caaatgcctg
    14821 taaacctccg ccctctggac gccgaacact tccctgcctg gcttgaacgc agtcgagccg
    14881 aatacgccaa ggagctcgtt gctctggggc agacgtccga ggacgcctac cggcaggcgg
    14941 acgagaccat ggcgctctcc tttccgtccg ggacaccgac cccggatcac gcggtcttcg
    15001 acgtggtcga cgatgccggg gtagccgtcg gctacctctg gatcggaccg gacaggagtg
    15061 acgacgccgg cgcctggtgg gtctgggaca ttgcgatcga cgctgacaag cgtggtcggg
    15121 gcctgggccg aacggccatg ctcctcggcg aggaatacgc ccgggcgcgg ggcgctcgta
    15181 ctctgggtct cagcgtcgcc gggttcaaca ccggcgcacg tggcctttac gagtcgctcg
    15241 gctacgagac gacctcggtg aagatgcgca agaaactcgg ctgagcctca ggcgacgttt
    15301 accctgccga cgacggcgcg taggcgccgg tcgtcggcgt gacggttttg ccagatgacg
    15361 tagcggcgga tcatgctgcc ctgttccttt tgaccggctt gatgtggccg tagagcctgt
    15421 ccctgaccag gtccagggcg gcgaagaggt gacgcacgcc gccgtagcgg ttgtaggtgg
    15481 cccggggcct gcggcgtggt tcgcggtcgg ggtctttgtg cttgccgccg cgttcggccc
    15541 attgcccgca ggaccggccg gatatcgccg aggtcgtacg gcgctgccgt gcgctgatcg
    15601 agacacaagg gctgcaggtc gcccaggcac gccgcaggct caccacgtac acgaccgctc
    15661 cgacccacgt cctggacggc ctcctcgccg tcggccgtat gtccgggccg ggggtgcgca
    15721 tggtgcccgg aacagccggg gcggcgctct ccgcccgctt cagcgcgctg cgcgcaccac
    15781 gctcgctgcc gggctccgtc gtcatgaacc gttgacgcgg ccaaggactc cggacctcca
    15841 gccggtcccc aactggtccc caagaaagat caagggccgg tttcggattg ctccgaaacc
    15901 ggccctgatc tacgactgtc tccagtcggg acgacaggat ttgaacctgc gaccccttga
    15961 cccccagtca agtgcgctac caagctgcgc cacgtcccgt cgcgtttccc ccggtttccc
    16021 cgggtgaccg cgcaggacaa acattacctc actcggagga ccgtatcgac gcccttgcct
    16081 gttgggcgcg ggcggccagc ccctcggctc cgcaggccat cgcctgcttc tgggcgcggg
    16141 cgagctcccg gtgcgagccg atcgcgatgc cgtagtcgac ccgggcgagg gcgtgctcgt
    16201 acgcggagga ggacttctcc aggtggccca ccgcttcggc gagcagctgc gcggcccgct
    16261 ccgggggcgc gaagagggcg acgcagcgca gtgcctcgcc catggcggtg ggcgtgccga
    16321 accgttcggc gtgcacccgg ttccgggctg cgagatgggc cgcgcgggcc gggtcgtcct
    16381 cggccagggc ccgcgccagg tcgccggccc agggagccca gatgccgttg aagcgttcgc
    16441 gcgactccag agcggcgccc gccgcttcga gctcggcgat cgcctcctcc ttgcggccct
    16501 ccgccagcag caggcggccc cgcatgcacg gtccgtcggg cagcaccatg gcgctggggt
    16561 agggcgggcc gaagtcgtag cggtcggcga tgcggcgggc ctcctcggtg cgtccgcggg
    16621 ccagcagggt gtcgatgagg aggcaggccg cgtcccagtg cacggggagt ccggaaccga
    16681 cgcggtcggc gaggcggagc ccttcgcgca ggaagccctc ggcctcggcg aggcggccgc
    16741 gacggcggtg gaccatgccg agcagggtgt gggcgaacgc caggtgggcc ccgctccagc
    16801 cggagatctc gaaggcccgg accgcttcgc cgaagaggct ctccgcgcgg tccagctggt
    16861 cgacgaaggt gtaggtgatg ccgaccatgg tggggagttc gaagccccac tcggagtcgg
    16921 tccagccgag gccacgggcc gggctgccgt cgatcagggc gcgttcgcac aggtccacga
    16981 tgagctgggc gttctcaccg ccgcaccatg gcgtcgaagg cccgcagcgt gagcagcgcc
    17041 cgctcggcgt tgtcgcggcc cttcaggtgg tcggcgttgc gggtgagccg ccgggagcgg
    17101 gcgggtccgt cgtcctcggc ggcctgcatg ccctcccaca tgaagtgcgc ggcctgcaga
    17161 cgcatcagcc cggggccggg tgcggtgcgt gcggcctcgg cggccagcga gagcgccgcg
    17221 tccttgagct ggttgttgtg ggcgagcgct gcggcgagcc ggaaggtggc gtcgacccgc
    17281 agcccgtcgt cgagccccgg catgtccagg gcggcgcgca ggtgctggac cgtggtgggc
    17341 ggggagctca gcagcgtcgc gcagcccagc tcgtacagca ggacggcccg gtccttgggg
    17401 cgcggcggct cctcgatcgc ccgttccagg cagcgccggg ccgcttcggg cgcaccgacg
    17461 gcgaggtgct ggccggcggc ttcccgcagt tgcgcgacca gttcctggtc gtcgtccggg
    17521 tggacctcca gcaggtgccg ggaggccgcg gcggcaccga ggccggcccg ggtgatcgcc
    17581 caggcggcgc gtccgtgcat ggcggtgcgg gtggccggcg ggatcgagcg gtagaccgcc
    17641 gtcgcgatca gcgggtggac gaactccagc gggtcgaagc cgctgacgat acgggcgtcg
    17701 cgcagccggg ccgtgcagtc ggcggcctcc gccgagctca ttccggcgag tgtggcggcc
    17761 agttcctgcg agatgtcggt gccgagcacc gcggcggccc aggcgaaccg gttggcgttc
    17821 gtcccgaggc gctccagccg ggcgacgagc ccgctgcccc tggcggacgc gccgagctcg
    17881 cgcagttcgc ccgcggattc ctccaccggc ggcagttcgc ggtcctggac cttggcaacc
    17941 agctcgaccg cctcgtacgg gttgcctccg gtgacggccc acacctcgcg gcagaacggg
    18001 tcgtcggcgt gatcgccgag gcccgcgcgg accagcacgg cggtggcgtc cggggtcagg
    18061 gcccgcaggg cgacccgggt cacggtgccc ttgctgccga agccgcgctc ggcctcacgg
    18121 tcggcgatgt agttggcgtc gcgctcggcc agctcctgcg ggcggtgggc ctgcaccacc
    18181 aggaccggca gttctccgag gcgggcggtg aacgaggcca gccaggcgag ggattcgccg
    18241 tccgcccagt gcgcgtcgtc cacgatcagc agtaacggcc ggtggctgag ccgggacgcg
    18301 agccggccga cgacgaagtc caatccgtcg cggacaccct gcgggtcggg ctgcgggccg
    18361 ctcggctcgg cgagtcccag ggccggggcg gtcgtctcgt accagtcgcc gaacagggcg
    18421 cgggtctcgt cgggcgggaa ctggtcgagt gcgggctgca gcaactgccg tacgacgtgg
    18481 aacggtacgg aggtgacggt ctcgcctccc cgggcggacc acacggtgca acggtcggcg
    18541 gccatcctcc ggatctccgc gagcagtgcg gtcttgccga tccccgcctc tccgctgaat
    18601 accaggagtc cgccgacggc ctgcgcaccg cacagggcgt ccaccgcctc cgcagcggcg
    18661 gcgagttccg gttcacgctc gtacaacggc cgggacggct tcatgcccac ccttcccaca
    18721 gaggcagtct tctcgacggt cgagcctagt cgtgcgcggg tgctcgccga cagggttcgc
    18781 acgattctcc gcaggtgcgg ggcacaatcg agtagtgaac gagacgcgca gagaccgtga
    18841 tgccgagggc cgggcgcgca acgcgcgccc ccgtgacggg ctgggacgcc ccctgccgta
    18901 cgggacaccc ggcgtcgaac gacagccgga gggggtcgtc cgcacgcccg cggagacgct
    18961 ccgggaggcg cagcggctgc tggacgcggg gatgccgttc cacgcgcacg aggtcttcga
    19021 ggacgcctgg aagtcgggcc ccgaggacga aagggagctc tggcgggggc tggcccagct
    19081 cgcggtcggg ctgacccatt ccgcgcgggg caacaccgcg ggcggggccc ggctgctgcg
    19141 ccggggcgcg ggggcactcg ccccgttcac cgggtccggg ccgcacggga tcgcggtctc
    19201 cggactgtcc gactgggcgc gggagttggc ggaccgggtg gagtcgggcc cgacggtcga
    19261 cgcggcggcc gaggcacccc gcctgcgggc gtagcccgaa gaccgggacc cgtgggcccg
    19321 gagcgggagc ggaagatccg ggtccgcgga ccctggcacc gtacagctac tacgatccgg
    19381 ctccatgagc acttctgacc aggaccagca ccgggaccag cgcgaggacg ggctgaacga
    19441 cgaggagccc gaccgggacc aggaacgggg ccggggcgcc gacacctcga tagccgagac
    19501 cgccgcggag acgaagacgg cggcggcaga gacagtggcg gcggagacgg tagcggcggc
    19561 ggagacggat ggggtcgacg tatccggcgg tgaggaccgt ggggacggcc agaacgacca
    19621 ggacgggaag agactcaccc cgcgccaggc ccggcagctg cggatcgcac tctcctcggt
    19681 gggcatggcg gcgatggccc tcgtgctcgg gctgcgcatc gcgagccgct cgtcggtgct
    19741 cgtggtcggc gtctacgggc tcgcgctcat cctgtgcggc gtggtgatcg agctgagcag
    19801 gaacggtcgc accaggctgg ccagctggct gctgggggcg gggctgctgg ccgccgtggg
    19861 agcggactgg ctgctgcttc cctgaggcgg tggcacggcg gcaatggcgg cctcagatgt
    19921 ccatgtcggg agggttggca ggcgcaccgg tttccggccg acggacgcga gaccctcacc
    19981 tcacccacca cccaccaccc acacgatgag cgtttgatcg atttgaccct cttgcgatcg
    20041 atctattgac cccttttgat cagtcgctca ggattcccgc atgaccgtct cccctggtgc
    20101 tctcttcgga ctccccccgg aagaccgcac gtcgagcccg tacaccggtt acacccgtgc
    20161 ccactgggag gcggcagccg acggaatgct ggccgccgcg tggaagtggg ccacgccggg
    20221 cggcgcccgg ctcgacctgc ccggtccccc gtctcactcg ggtgtccgct cggacgggct
    20281 ggaggggtac gcgcgcacgt tcctggcggc cggtttccgg gtcgcgggag cgggcggcaa
    20341 ggacccgaac ggcctgctgg agcggtacgc ggacgggctc gccgccggta cgcggacacc
    20401 gggccgggac gacgcggagt cctggccgct gatcctggac cacgatgtgc agggacagcc
    20461 catggtggag tccgcctcgg tggccctcgg tctgcggctc acccggccgt ggctctggga
    20521 ccggctgacg cccgacgtgc gggaccgggc ggagcactgg ctgcggggcg cgctgcggca
    20581 cgttccggcg ggcaacaact ggtacctct
//
