LOCUS       NZ_LIVW01000002        22552 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02115 scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_LIVW01000002
VERSION     NZ_LIVW01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02115
  ORGANISM  Streptomyces sp. CB02115
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1550960)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1550960)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905645.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,651
            CDSs (total)                      :: 7,572
            Genes (coding)                    :: 7,475
            CDSs (with protein)               :: 7,475
            Genes (RNA)                       :: 79
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 34 of 97
            Pseudo Genes (incomplete)         :: 79 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 23 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:09:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 763115
            Orig. end                         :: 785667
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVW01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22552
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22552
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22552
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12552](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12552)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    571..580
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.04"
                     /tool="antismash"
     gene            840..1214
                     /locus_tag="AMK28_RS13935"
                     /old_locus_tag="AMK28_13735"
     CDS             840..1214
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="AMK28_RS13935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13735"
                     /product="ATP-binding protein"
                     /protein_id="WP_241837511.1"
                     /transl_table=11
                     /translation="MAFRPDPRWVSETRRTTAAFLQRVPVPEPLVSDIVLAVSELVTNA
                     IVHGDGDVCLRVSVGGQEVRVSVSDQSPERAVLVQAEDDRESGRGVLLVAAFAQAWGSS
                     GAETWCSFRYPEKADTRAVA"
     gene            1211..2119
                     /locus_tag="AMK28_RS13940"
                     /old_locus_tag="AMK28_13740"
     CDS             1211..2119
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS13940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13740"
                     /product="hypothetical protein"
                     /protein_id="WP_073741655.1"
                     /transl_table=11
                     /translation="MSAVAVRLPQAQFAAGARKAIASLSDAFLRDEDLANDLDQILGAP
                     AGPVGLAGGRSRRRCGLFRSATSRPSDEEAAELSRAVTRLDRMLERLVAIAEFREWEPP
                     YPRVQAAIVQAKAVRDQQPQVVGGFETDRAHLRLMAMAAADILARLIDDDEERVMSLPR
                     AYWCHAALEASTPGASRTEGCTKASAEAAVDWVRESVRRVSPSLDRSTFHRVWGWLGDH
                     RAVRAAVIALRQSEPYNFSIDIPAGRLAWTVHHVGQLPLASPCGCRPFSDYNSLSTPPR
                     LGAPPADSARLPMPSTAIGAS"
     misc_feature    1442..1444
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2230..3294
                     /locus_tag="AMK28_RS13945"
                     /old_locus_tag="AMK28_13745"
     CDS             2230..3294
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS13945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13745"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_158073334.1"
                     /transl_table=11
                     /translation="MIASAADIVRHCETVWGLVEPWLPQAQARLRAADGSASDAARWRS
                     TIGAVSRVDSHALTSDDLLELCSAARRLLGRLMEAERPGPSVAEIAARLRELITSGAFP
                     PGSPLSVARIAAGLGCDRASRVRVELALRDLEIKGEVTFGRSNRASVVGEREAIDRPAQ
                     IAEWLRDLIKAGVYPRTTELPWVDPLSRSFVSPRDTVMRALDILVDEGVLLRGPKKRPA
                     VCWKLPFPVAFPPDIDSLLAELTDVVPPDMDLSPYRVEEACRRARSSWSSRISPLPEDL
                     THTIGVLVGAAEQLIPLAALRYADNEEVETRLRRTAVTALADPPPDVLRRTWHAACLGA
                     AVQDILLLLAGDLT"
     misc_feature    3241..3243
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3291..3908
                     /locus_tag="AMK28_RS13950"
                     /old_locus_tag="AMK28_13750"
     CDS             3291..3908
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036898.1"
                     /locus_tag="AMK28_RS13950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13750"
                     /product="DUF6624 domain-containing protein"
                     /protein_id="WP_073741657.1"
                     /transl_table=11
                     /translation="MSTDPRPDDGAAGTAPCRRPDIARTLIGCVENAVPQWARIARSQI
                     TEHEIEMFRHVDHANAQLLGRVIRDHGWPGYRLVGEDGARAAWWIALHADSLLTVQNLA
                     LQLMHEAVRQGDASLPQWAHLTDRALTNAHKLQEFGTQYRQGASGLERQPVHAPDTLDQ
                     RRIAMGLVPGADALETLRRRLDAAPRYGALPGEPPADLSGTA"
     gene            3905..4273
                     /locus_tag="AMK28_RS13955"
                     /old_locus_tag="AMK28_13755"
     CDS             3905..4273
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039764.3"
                     /locus_tag="AMK28_RS13955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13755"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_073741658.1"
                     /transl_table=11
                     /translation="MNGPGGVRTESARKLTKKVLAWSTSEEKAPTLEEADTALALLTTY
                     GKEFRDTVTTAYHQLPAGSAVAERVQATLGEASRRLDHPLPERTRKAVVGRAQNIARLL
                     EALLRAAATTEHEDVDRP"
     gene            4270..4986
                     /locus_tag="AMK28_RS13960"
                     /old_locus_tag="AMK28_13760"
     CDS             4270..4986
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042672.2"
                     /locus_tag="AMK28_RS13960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13760"
                     /product="DUF6624 domain-containing protein"
                     /protein_id="WP_073741659.1"
                     /transl_table=11
                     /translation="MTSFRPDLAINLFARADAARPAWSARLSYEERVKQVVLPGRWDVD
                     RENTEFLRAAMEEHGWPGHRLVGEGGAHAAYLIALHADHDVDFQWLASNALGEASAMRD
                     ARSEDWAHMYDRCHVNSGKLQIYGTQYRYGLNGPELLPASLDDIDWRREFVGLRPIAEA
                     RAAVLHRHSPDRPPGDGLEEEPGPRGRLLWVLRPHAHARAPPERSRKSSAPQQVRRAPT
                     PLRGRIRRSPSDRKGC"
     misc_feature    4989..5004
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            4990..5445
                     /locus_tag="AMK28_RS13965"
                     /old_locus_tag="AMK28_13765"
     CDS             4990..5445
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039985.3"
                     /locus_tag="AMK28_RS13965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13765"
                     /product="DUF6082 family protein"
                     /protein_id="WP_073741660.1"
                     /transl_table=11
                     /translation="MKITTAVLLAGAAAAGVGVAHLWQAERHQRQRNALSAASMHQEYL
                     RYVEGNPELQRLWVPEDGSLDPEEYLRRTHANHLFSALAVRFRVGIIDEENLRVQANWM
                     MSRALGRDYWSSFSGFRESEARDKVDRRFNRIMTSEWLARPEVDALV"
     misc_feature    5693..5705
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            5693..6121
                     /locus_tag="AMK28_RS13970"
                     /old_locus_tag="AMK28_13770"
     CDS             5693..6121
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS13970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13770"
                     /product="hypothetical protein"
                     /protein_id="WP_073741661.1"
                     /transl_table=11
                     /translation="MHSALLESPDTQVRYRVMTGEDDDRGRRGAKQIVGRSEVSLHCKD
                     AATIEKTVEALRLSDAELVKRPEASRKYDWQSVFVEPDQGSADGGGNVLFGVAWYDEDY
                     FTEKAEVYGDKMHSHMFGNLGITEKDVTVTHWRAAIAA"
     gene            6207..6995
                     /locus_tag="AMK28_RS13975"
                     /old_locus_tag="AMK28_13775"
     CDS             6207..6995
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025217.4"
                     /locus_tag="AMK28_RS13975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13775"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_073741662.1"
                     /transl_table=11
                     /translation="MTDRMEQGARWDLWAPHYDQDTAGQDFQPAAAGLADLAGPGPVLE
                     LGIGTGRIAFALAEWGVPVTGIDASSQMIERLDRRAVQEPPRVAVRAVTGDMARFDLGE
                     LFPLIYVSVSTIFLLTSQDDQVSCFRSAAKHLSSDGRFVVEAAVPYASGLATERDQMIV
                     REMSDNHLKWSAFLHDAATQTVRAQEVRIGTEDGFRMLPNLMRYAHPAELDLMAQLAGL
                     RLERRTADWAGNPFTSTSTHHVSVYSHLPAEPALPTGAPA"
     gene            6992..7885
                     /locus_tag="AMK28_RS13980"
                     /old_locus_tag="AMK28_13780"
     CDS             6992..7885
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="AMK28_RS13980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13780"
                     /product="hypothetical protein"
                     /protein_id="WP_073741663.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-12, bitscore: 43.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNVLPQLLPEAFGTAETAHVSLVADRRGTALWQVHLDDGSRYAL
                     KATTACTDPQGHVDSEHLALVEAELLMALERAGVLRHLYRAHGDLPDGTGTWLTLRWLP
                     GEEAETAYGKLRTTPDDRTAARYAAAMAGAVADLHEAGWTHGDMQEVHFILDGDSAHLL
                     DFAMAQPPAGIRIAAHRAPYRGAYDFFMSPELAARRLATKPSEHLELTTASEVWSLCAT
                     IYACWTGVYPISEKDTKLSTPDLRAELAHGRYRPLPMVRPWAFPAFEDIISTGLVIDPT
                     ARPTARELQHMFQELV"
     gene            complement(8004..9944)
                     /locus_tag="AMK28_RS13985"
                     /old_locus_tag="AMK28_13785"
     CDS             complement(8004..9944)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="AMK28_RS13985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13785"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_073741664.1"
                     /transl_table=11
                     /translation="MKTTHHQQSDPAPRVPWRRRARPAATDVIPQYAVSAERHDSALDD
                     SFATMARRLPALSATALRLAWQADRPALLLTALLQVGTGIVTAIGLYATKGALSPLFGS
                     GLAADRLHAALPAIIAIMTAAAARSLIAAATLATTARIGPRVDAIAELRYLHAATSVPL
                     ASYDDPAWCDQSEAANRASKDTHLMIDALTAVSTALVGLLASAGILAALHPILLPLLLL
                     AVVPRAAAAVQAARSAYRAERHTLADRRLRHTLIYNTAGRPTALDVRAATMRPWLLSRF
                     SEVTERLTAHAARVGRETGRYQLLGDALAGAAAMLVYAALAALVISGRVPLAAAGTAVV
                     AVQASRVMLVGLVTGMNTTYKTGLYLGDWADFVADAERRTRARDFTGTVPTQPDVIRAK
                     DITFRYPGHTAPALDGVSVTVRPGETLAIVGANGSGKSTLAKLLAGLYEPTQGVVEWGG
                     VDLATVDPETVWAKLAMLPQDIARWPVAARENITLGQGEGDDQAVMEAARLAGADEVIE
                     QLADGLDTNLAPSQWGGRDLSGGQWQRLAGARAFFRKDAPVLICDEPTSALDPRAEEAM
                     YEQIRTLGAGRTVILITHRLGSTRNADRIVVLDRGRLIEEGTHESLLDLDGEYAAMWRT
                     QAQSYSWPVAM"
     misc_feature    9994..10009
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.59"
                     /tool="antismash"
     gene            complement(10001..10717)
                     /locus_tag="AMK28_RS38325"
     CDS             complement(10001..10717)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="AMK28_RS38325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_079199001.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.7e-11,
                     bitscore: 39.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.1e-15, bitscore: 54.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAARVFAADTGDGVALMDLGTTRGKWRFLDPVGAGLWRKVVSGT
                     PREQAVEELVTYWAQRGIDPDRVRADMNALAGQLDAEGLFTAAPHPPTSRAPEVRYVDT
                     VAQSRPVVRAAGHVGLGTALVLLRCLPVRLVVRAARLAGRLPGRAASQEEADAVCAAVR
                     RAVGWWPGRAACLEESLAAYLAAAMTGRRVAWVLGARFVPQGAHAWIATADAVHGQEPA
                     DRVWPYRAALTVESSN"
     aSDomain        complement(10460..10708)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AMK28_RS38325_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="9.70E-13"
                     /identifier="RREFam002.1"
                     /label="AMK28_RS38325"
                     /locus_tag="AMK28_RS38325"
                     /protein_end="86"
                     /protein_start="3"
                     /score="39.0"
                     /tool="antismash"
                     /translation="ARVFAADTGDGVALMDLGTTRGKWRFLDPVGAGLWRKVVSGTPRE
                     QAVEELVTYWAQRGIDPDRVRADMNALAGQLDAEGLFT"
     gene            complement(10714..12552)
                     /locus_tag="AMK28_RS13995"
                     /old_locus_tag="AMK28_13795"
     CDS             complement(10714..12552)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="AMK28_RS13995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13795"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_073741665.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.7e-31, bitscore:
                     105.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFIMGTTAAAGLGWRPKGAAEVAGVGGLGVWANEFRADEIRRGS
                     FGDGTVVVAGSCLASVVELERAAAAAARGDWVAAARLPGVALVLVRTGRVWRVMGDRAG
                     TVQVFWMRFADRVLWGTAAAPLASLGGYEADPAVLLGQMMLQGVDVLDGASHFHGVRRV
                     RPGHALVLEEGQSPRTEPVAPPVGRLAFDKAAPLARDAVVEAVQRRTMTGGLISADLSG
                     GMDSSVVASVAAMSTRLLAVTYTDARMKDEDDVRYARQVAAELPGVRHQVVEGGTGAVR
                     HFGGLDDPHLLPLTDTPTYSLGLLEMKRVQLAEPVLSGSRLHLTGRGGDDVLDAVGSMP
                     LDQFRAGQRAAAWRRVAALARARRASGTELLAQAARTIATPYPHALEVLADRVEAGRTD
                     GPAGAARILAWSGVGGALPWLTRSGRSLVAGLVGARATSADRRETPGRLHERLALELMG
                     DGHSTFDQMSRTLWDLPVHAPLLDNRVVDVCHAIPGWERSRPGAFKPLAGAAFTGLVPD
                     VLLERRTKTPFTGSLYDGLRAHAPAVRRILTGSILVQADLLDRRQVMGALDAGVRGETI
                     PLAALHGLVAAELWLALLPLGRSAWWERTDAPRVAA"
     misc_feature    complement(12307..12309)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12667..12792)
                     /locus_tag="AMK28_RS38740"
     CDS             complement(12667..12792)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS38740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_107418268.1"
                     /transl_table=11
                     /translation="MIENANDWIYTTPAVSELGTVVEVTLGSAGNDNADDTQYWS"
     gene            12993..14237
                     /locus_tag="AMK28_RS14000"
                     /old_locus_tag="AMK28_13800"
     CDS             12993..14237
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="AMK28_RS14000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13800"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073741666.1"
                     /transl_table=11
                     /translation="MVTPDGIGQLLREVRERAGRSRAEQARRLTAADRHCTEENVKRWE
                     LETRLPSPVWYPAIVSVYGLGEEQVRGAVAASRWYRKQRKESEDVERRKFLGGAAATVG
                     TVALPGIAQAREHIDSALAPTGEADVAYFEGVFERHRGGYAGRTPDAVLGLMEQDLEEL
                     SVALRRTRHAGDRSDLVRAAAGITGLVAIIQHDRGDRADAHRWFAIAGKVARESGDRRT
                     LSWVLARRAMVPLNYGAPRQAAEYAQAARQAAGRTPTGAAALASAVHARALAALNDVNG
                     ARKAIASTESLLQRIDGEETADTWFGYPGQKHEVHLSQAYTLLGDTKAAYRHQDAALAL
                     TRSPSVMTRALLALDTAACLRTDGDHREAASMAAGVWGRLPVEHRSGLIRARATVLLDR
                     LDGAAHEHLREALAS"
     misc_feature    13020..13022
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13527..13529
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14318..14695
                     /locus_tag="AMK28_RS14005"
                     /old_locus_tag="AMK28_13805"
     CDS             14318..14695
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS14005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13805"
                     /product="hypothetical protein"
                     /protein_id="WP_143203432.1"
                     /transl_table=11
                     /translation="MDQTNVTAAARRVVITTRGAGVDIDIDGKRIEPNAVKAYSVSHLA
                     GEHPEVLLHVADRNDVQWSGTARVAVTDLPDPGPAAAVFLDAIDPEALERAALARPDLG
                     TEPGSLTKAMLTQLGEWARGL"
     gene            14685..15116
                     /locus_tag="AMK28_RS14010"
                     /old_locus_tag="AMK28_13810"
     CDS             14685..15116
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039652.3"
                     /locus_tag="AMK28_RS14010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13810"
                     /product="DUF6093 family protein"
                     /protein_id="WP_143203433.1"
                     /transl_table=11
                     /translation="MAFDVDGARRVVGRILDDKLEVWRDDAGRTDDVLDEATGRLVPPA
                     PDEELVWDGLGAVMPLGRPAITKPVGGSVAVEPPTTDYQAVLPIGAPALRRDDVVRVAG
                     SVRPGGPRDPQLVGRRFRFSDETVGTYSVVRIVRVQVID"
     gene            15116..15544
                     /locus_tag="AMK28_RS14015"
                     /old_locus_tag="AMK28_13815"
     CDS             15116..15544
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016754.4"
                     /locus_tag="AMK28_RS14015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_13815"
                     /product="HK97 gp10 family phage protein"
                     /protein_id="WP_073741669.1"
                     /transl_table=11
                     /translation="MALANTHPNAHPDATAFRDPIALAAALARMGPATRARTRTITRHH
                     AMLLRVRIQRNASGRPGPNVITGQYRASWDVRMRTGGGEVTAEVFSDAPQSRRLEYGFV
                     GVDSIGRHYRQPPFPHVEPAFRQTEPDFVQALADGVLP"
     gene            15541..15984
                     /locus_tag="AMK28_RS14020"
                     /old_locus_tag="AMK28_13820"
     CDS             15541..15984
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS14020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13820"
                     /product="hypothetical protein"
                     /protein_id="WP_073741670.1"
                     /transl_table=11
                     /translation="MTARLPVTRALAALVEKATGRPCGTGELPRVEGKSGWVPASPPYT
                     ILDSLPGEFGGPPLWDWHADAAWSYQVTSVGERGDQVEWLADRVRAGVVGRTDGHWAYD
                     LHVPEARVIDRELTYDAGGEPSVSAAGAIVSYVQRVTITVTPA"
     gene            16119..16763
                     /locus_tag="AMK28_RS14025"
                     /old_locus_tag="AMK28_13825"
     CDS             16119..16763
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS14025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13825"
                     /product="hypothetical protein"
                     /protein_id="WP_073741671.1"
                     /transl_table=11
                     /translation="MSTSTKKNIQTRFLRRGISKILWVPDLNDPKYPSRREITKAFVLT
                     DAVSDIEGWALENDPIETPDMGSTFNSSIPGNDKAENSSLTFYEDRFSDAIEQQLPKGA
                     KGYVVLLRKGDLPGSRSVDVFPVQVATRAASYSTSNEAAKFQVTFTVIDEPSLDRPVPQ
                     AQARPLPDEDCETDHDHGHHDGDHVDVTVVSTTKTKTETEATVREHDADEG"
     gene            16766..17320
                     /locus_tag="AMK28_RS14030"
                     /old_locus_tag="AMK28_13830"
     CDS             16766..17320
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS14030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13830"
                     /product="hypothetical protein"
                     /protein_id="WP_143203434.1"
                     /transl_table=11
                     /translation="MSRPAQAKRPAPSASPAEGAWAAKMERLRRRRKVQNRLRVCDDNE
                     LRQRYDEAEQAARRARFVAEANPGDELAERQAADADTARDQALAALDAASEFLAFRALP
                     RPVLEELISEHPPTEQQVEEGAIFNAVTFPGALVAAASVDGMSREEAEELLNGWSAPDA
                     NALWDAAWQVQQESRVELGKD"
     gene            17434..17661
                     /locus_tag="AMK28_RS40050"
                     /old_locus_tag="AMK28_13835"
     CDS             17434..17661
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AMK28_RS40050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AMK28_13835"
                     /product="hypothetical protein"
                     /protein_id="WP_241837495.1"
                     /transl_table=11
                     /translation="MAWAEWQRSVCPECRTRLEEWDRTRGGDPHAYVTDTLRCPGCELI
                     EQERDHVPQDRSGYGVKIQLLPREQYESRS"
     gene            17696..21964
                     /locus_tag="AMK28_RS14040"
     CDS             17696..21964
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /locus_tag="AMK28_RS14040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phage tail tape measure protein"
                     /protein_id="WP_073741674.1"
                     /transl_table=11
                     /translation="MAGFTLTVAMRAEVRDLIAGTRAASAQMRTLGDRTDAANRSLARL
                     DANGARLASQFAALNRSARGAVGELNRITARAGAARAALRSAGDDGARSMSRLQRATAG
                     AGRRGTSATNMLAGGALVLGTGEIIEEGNRYQRQMNLFRAVTDATAGQMQRAGVVAREL
                     GNDLTLPTSTSADAAEGMVELSKAGFRADQSIDAVRASLQLAAAADVNAATSAKYLGDI
                     MDQYGLGADQASRAADTLAATANNASGSITDIYYSMRYAGPVANALGVTLQDTAAAVGM
                     LGKSGILGQTAGTSLRGIFANLAAPTPIMKNALRDLGIEAWDAEGRFRGLRTVIDGLSE
                     AEHSMNQQDFVAGVTRAFGKPALSGAVALAHQGTESFDALSMAVEQTGSAADITASRGE
                     GLAGAMTQLRTQARQTGIALYDGMAPGLEWVTRLLTRGMSGATPYLTQAIEYGNDLATL
                     FGPELKAQTKDGLSGLIEEAQQLVGPLKDIGEHSLATGLNLLINAGRTLGDVLENAADG
                     AEPILEAVSGLGEEGGAAAGTLDIIATVGNIAMDAVSGLSMVLVPIGHAVGGLVSAFGA
                     LPGPIQSAALAMLLFRRAQPALTNMATTMTGPVRSGISSFNQQMRVQQSLAAASGVALS
                     RYGAAWAAVQARVGFLGNMTSAFRSANGAGTTFVGTLNGVGRAAGSGLRSALGGVTNAL
                     GGPFGVVMAGVSVGLGLLASRQQKAAQAAAEHQQRVSTLTSALRESGGQIDSNVRNAAA
                     QSLLDTKTEQGELAKVMDQAGVPLASLTDAYLGQGTSLDALQKQLQATADKHKVWKNVA
                     GGKATVQDYSEVGQQYKDAADALGSVKGEMSGALKNAKDLAKATKGAADGTSAYDRLKA
                     AVGGLADQTADADTRTRSLKSALDLLSGGQISLQAAEAKVNSAVLDLEDGSKNVDRSQG
                     YGGKQLVNEDKTLNTTTRNGQGLYTQLTALSDAAADASVATFDLAQRNGEDLPAALAKA
                     REQMSRARSEAIQAARGYGLTKAQAEGVADSLGLLPSKVSLLLQTKGMDSTLANLIAVQ
                     AEFQRLPNAKTIKVDSLSDGAQKKLRSLGFTVKTVPGTRQIKISAPTAGAKKNLDTLID
                     KLGRTPNSKNVKVSAPTAAAIKSLEGVQAKIRATPGAKSVVVRAPTAEARKQLEALGFK
                     IEKVPGSKNVKVTLPTGGPRKAADSIQARINALRGKEVTVTTRHVTIFDQLRQSNSDTA
                     DAIRRQAEAQARAAKKHADGAVVDYFADGGVTGGTGRERHVAQIAPAGSYRVWGERETG
                     GEAYVPLAAAKRERSKAIVETVVDRFGGNVEWYADGGVRNARGRDYSPTLASSFKSARS
                     VAAMAGVVRSFDLRTGSDRARTRVVDARAGGRVQVVVVREQQPLIGSMPVSVSDSSATP
                     EQIGNEMMRTLRNAQRGGRV"
ORIGIN
        1 tgcgcctcca gcagcgcctt ggcgtatcgc tcggtctgga gcagtccgta caccagagtc
       61 gggtggtagg cggtaatcac tatggcttcc gcttcgaggc cgacgtggtg aggcattccc
      121 gtaggcatga agctgcggta ctgcgtgagc cagtcctcgc cgggggcgtc gcggttcagc
      181 tccacgagct gctggatcag ctcttcgtcg gtcacgccgt accgcctcag cagggtcctc
      241 aagttcccga cgttgcgacg gaagttcgcc tcaccgccct cgatgcgacc aagcgttgcc
      301 tccgacagac tcttgagtcc tcggacggct tcctttcggg tcatgccctt gacccggtcc
      361 ttctccgtcg gcgggcaatt ttcccgtaga tgtctcatct gcatgccgag ttccagccgc
      421 tggccggtag ctccgagctt cgctgccacc tgtgcacctt cctagcgtcc ttgtgcatgc
      481 gagccgacct gtgcgcaggg gctgataccc gctgagcatg cagtgcagtc ccctgtgcac
      541 gttgctgcat agtccatttt gaggactcgc tgatttttca ttggagaccc gcttgcgatt
      601 caacgttact tacggacacc gtagttcaca cggaatccga gagggccgga tcgcaggtca
      661 cgaggcgtct acggcgtctc gcagcggtcg gctccctccc cgccgcactc cccacgaagc
      721 cgaggccaac catgagccag agccccaccc agcgtaggca gccggagcgc ctcgcacctc
      781 aaggcgaacg aggccgatcg aagtgcgagg acttaccggt gatggccgcc gccttccaga
      841 tggcgtttcg gcccgacccg cgctgggtga gtgagacgcg gagaacgaca gcggccttcc
      901 tccagagggt gcctgtgccg gagccgctag tgagcgacat tgtgctggct gtatcggagt
      961 tggtcacgaa cgccatcgtt cacggtgacg gggacgtctg cctacgcgtt tcggtagggg
     1021 gccaggaggt gcgggtttcc gtgtccgatc agagccctga gcgagccgta ttggtgcagg
     1081 ccgaggacga tcgtgagtcc ggccgcgggg tgctgctcgt tgcagcgttc gcacaggcgt
     1141 ggggcagtag cggcgcggag acgtggtgct cctttcgcta tcccgagaag gccgatacga
     1201 gggcggtggc atgagcgccg tcgccgtacg actgccgcag gcacagttcg cggccggagc
     1261 aaggaaggcg atcgcttcgc tcagcgacgc gttcctccgc gacgaggacc tggcgaacga
     1321 ccttgaccag attctggggg ccccggcggg ccccgtcggc ctggccggtg ggcgaagccg
     1381 cagacggtgc ggcctgtttc gaagcgcgac gtcgaggccg agcgacgagg aggcggccga
     1441 gttaagccga gccgtcactc gactcgaccg gatgctcgaa cgactcgtgg cgattgcgga
     1501 gttccgcgaa tgggagcccc cgtacccgag ggttcaggcc gccatcgtgc aggccaaggc
     1561 ggtgcgagat cagcaaccgc aagtggtagg cgggttcgag accgaccgtg cccatctgcg
     1621 cctgatggcg atggcggccg cggacatcct cgcccggctg attgacgacg acgaggagcg
     1681 agtcatgagc ctcccgcgag cgtactggtg ccacgcggct ctggaggcga gcacgcccgg
     1741 agcatcgcga actgaggggt gtaccaaggc atcggccgag gccgccgtcg actgggtgcg
     1801 cgagtccgtc cggcgggtga gcccgagcct tgaccgcagt acgttccacc gggtgtgggg
     1861 atggctcggt gaccaccgtg ccgtgcgggc ggccgtgatc gcgctccgtc agagcgagcc
     1921 gtacaacttc tccatcgaca tccccgccgg ccgcctggcc tggaccgtgc accacgtcgg
     1981 ccaacttccg ctcgcctccc cgtgcggatg ccgcccgttc agcgactaca actccttgtc
     2041 tactccgcct cgcctgggtg ctccgcctgc tgattcggcc cgcctgccca tgccgtccac
     2101 cgccatcgga gcgtcatgac caccgcgtcc acgaccacgc agcagtgcgc ggagggtgct
     2161 ccgtctgaga tggagtatca gactgttcgt ctgcatctcg ttgcgttgca gcggactacg
     2221 aacaggttcg tgatcgcgtc cgccgcagac atcgtccgtc actgcgaaac ggtgtggggc
     2281 ctggtcgagc cgtggctgcc gcaggcgcag gcccggctcc gtgcggccga tggatcggct
     2341 tcggacgcgg cccggtggag gtcgactatc ggtgcggtta gccgagtcga cagccacgcg
     2401 ctgacgagtg acgacctgct ggagttgtgc tctgcggccc gccgcctgct cgggcggctc
     2461 atggaagccg agcggccagg acccagcgtc gcggagatag cggcccggct tcgggaactc
     2521 attacctccg gcgccttccc gcccggcagc ccgttgtctg tcgctcggat cgctgcgggc
     2581 ctggggtgcg accgagcttc gcgcgtacgg gttgaactgg ctctccgcga tctggagatc
     2641 aagggcgagg tgaccttcgg ccgctccaac cgcgcctcgg ttgtcggcga gcgggaggcc
     2701 atcgaccgtc ctgcacagat cgctgagtgg cttcgcgatc tcatcaaggc cggcgtctac
     2761 ccgcgtacga ccgagctgcc ctgggtggac ccgctctccc ggagcttcgt atccccgcgc
     2821 gacaccgtca tgcgcgctct cgacatcctc gtggacgagg gagttctgct ccggggaccg
     2881 aagaagcgtc ccgccgtctg ctggaagctg ccctttcccg ttgcgttccc tccggacatc
     2941 gacagcctgc tcgcggagct gaccgacgtc gtgccgcccg acatggacct cagcccctat
     3001 cgcgtagagg aggcttgccg tcgtgcccgt tcctcgtgga gcagccgcat ttccccgctc
     3061 cccgaagacc tgacgcacac gatcggcgtg ctggtcggtg cggccgagca gttgatcccc
     3121 ctcgccgcct tgcggtacgc ggataacgag gaagtggaaa cccgtctgcg tcgtacggcg
     3181 gtgaccgcgc tcgcggaccc tccaccggac gtcctccggc ggacatggca cgcggcctgc
     3241 ttaggcgcag cggtccagga catccttctc ctccttgcag gagacctcac gtgagcactg
     3301 accctcgacc cgacgacggc gcggcgggca ccgccccgtg ccgacgacca gacatcgcca
     3361 gaacgctgat cggctgcgtg gaaaacgcag tgccccaatg ggcccggatc gcccgctccc
     3421 agatcacgga acacgagatc gagatgttcc gccacgtcga ccacgcgaat gcgcagctcc
     3481 tcggccgggt tatcagggat cacggctggc cgggatatcg cctggtgggc gaagacgggg
     3541 cccgggccgc atggtggatt gccctccatg ccgacagcct gctcaccgtc cagaatctcg
     3601 ccctccaact gatgcacgaa gccgtacggc agggtgacgc gagcctcccg cagtgggcgc
     3661 acctcaccga ccgggctttg accaatgccc acaaattgca agagttcggc acgcagtacc
     3721 gccagggcgc cagcgggttg gagcggcagc cggtgcatgc cccggacacc ctcgaccagc
     3781 gccgcatcgc gatgggactt gtgcccggcg ccgatgccct ggagacgctg cgtcgacgcc
     3841 tcgacgccgc acctcgctat ggggcgctcc ctggagagcc gcctgctgat ttgtcgggta
     3901 cggcgtgaac gggcctggcg gcgtccgtac ggagagcgcg cgcaagctca cgaagaaggt
     3961 cctcgcctgg agcacgagcg aggagaaggc cccgacgctg gaggaagccg acacagcctt
     4021 ggccctcctc actacgtacg ggaaggagtt ccgcgacacc gtaacgacgg cgtaccacca
     4081 actgcctgcc ggctccgccg tggccgaacg agtgcaggcc acgctcggcg aagcgagccg
     4141 tcgtctcgac caccctctgc ccgaacgtac gcgtaaagcc gtcgtgggcc gcgctcagaa
     4201 catcgcgcgg ctgctcgaag ccctgctccg cgccgccgcc acgaccgagc atgaagatgt
     4261 ggatcgcccg tgacctcgtt ccggccggat ctggccatca atctctttgc ccgcgctgac
     4321 gcggcacgcc ctgcctggtc tgcccgactc tcgtacgaag agcgggtcaa gcaggtggta
     4381 cttcccggca gatgggatgt ggaccgcgag aacacggagt tcctgcgggc agccatggag
     4441 gagcacggat ggccggggca ccgtctggtg ggtgagggcg gagcccacgc tgcctacctc
     4501 attgccctgc acgctgacca cgacgtcgat ttccagtggc tcgcgtccaa cgcgctcggc
     4561 gaggcatcgg ccatgaggga cgccaggtcg gaggactggg ctcacatgta cgaccggtgt
     4621 cacgtgaaca gcggcaagct ccagatctac ggcactcagt accgctacgg cctgaacggc
     4681 cccgagctgc tgcccgccag cctcgacgac atcgactggc gccgcgagtt cgtgggccta
     4741 cggccgatcg cggaggcccg cgctgccgtt ctgcaccggc atagcccgga tcggccaccg
     4801 ggagacggac tggaggaaga acccggaccg cgaggtcggc tgctctgggt gcttcggccc
     4861 cacgcccatg cccgagcgcc gccggaacga tcacgcaagt cgtccgcccc tcagcaggtg
     4921 aggagggcac ccactccctt gcgagggcgg attcgcaggt ccccatccga tcgaaagggc
     4981 tgttgacgaa tgaagatcac caccgccgtg ctcctggcgg gcgcagccgc tgccggagtt
     5041 ggcgtcgccc acctctggca ggcggagcga caccagcgcc agcggaacgc gctctcggct
     5101 gcctcgatgc accaggagta tctgcgctac gtggagggca atccggaact gcaacgcctc
     5161 tgggtgcccg aagacggatc gctggaccct gaggagtacc tccggcggac acatgccaac
     5221 cacctgttct ccgctctcgc cgtgcgattc cgggtcggaa tcatcgacga agagaatctg
     5281 cgcgtccagg cgaattggat gatgtcccgc gcgctcggcc gagactactg gtcgtccttc
     5341 tcgggattcc gcgagtcgga ggcccgcgac aaggtcgatc gtcggttcaa caggatcatg
     5401 accagcgaat ggctggcccg cccggaagtg gacgccctcg tctgacccgc cgcagacccg
     5461 cgtcacccaa gactccctgc ccgcgctgcg gaatcgcgcg ggtgcagggg cacaaccccg
     5521 ctcgggacgt cacgaatccg acgagcgggt aacgccctgg ccggcagacc aatgccgact
     5581 gcgacacgga cggacaggtc accagacccg gccagggcgc gcgcatccca cacaccttcc
     5641 atcgggtgca accgacggaa gggccactcc acaggagcca agaggagcac acatgcattc
     5701 tgcactgctc gaatcccccg acactcaggt ccgctaccgg gtgatgaccg gcgaggacga
     5761 cgaccgcggc cgtcgcggtg ccaagcagat cgtcggccgc tccgaggtgt ccctgcactg
     5821 caaggacgcc gcgaccatcg agaagaccgt cgaggccctg cgcctgtccg acgccgagct
     5881 ggtcaagcgc cccgaggcgt cgaggaagta cgactggcag tccgtgttcg tggagcccga
     5941 ccagggcagc gcggacggcg gcggcaacgt cctgttcggc gtggcctggt acgacgagga
     6001 ctacttcacc gagaaggccg aggtgtacgg cgacaagatg cacagccaca tgttcggcaa
     6061 cctcggcatc accgagaagg acgtgaccgt cacccactgg cgggcggcca tcgcggcctg
     6121 acgccacgcg cacagcacac caccagggcc cggctcacgg agccgggccc tggcccgtgc
     6181 cacgacaacc acttcgaagg ggaacgatga ccgaccgcat ggagcaggga gcccgctggg
     6241 acctctgggc accgcactat gaccaggaca ccgccggaca ggacttccag ccggccgctg
     6301 cgggcctggc cgatctcgca ggaccggggc cggtgctgga gctgggcatc ggtaccgggc
     6361 ggatcgcctt cgccctcgcc gagtggggtg tgcccgtcac cggcatcgac gcctcatcgc
     6421 agatgatcga gcgacttgac cgacgcgctg tccaggaacc accgcgcgta gcggtacggg
     6481 ccgtcaccgg ggacatggcc cgcttcgacc tcggggagct ctttccgctg atctacgtca
     6541 gcgtcagcac gatcttcctc ttgaccagcc aggacgatca ggtctcctgc ttccgcagcg
     6601 cggccaagca cctgagctcg gacggtcgct tcgtcgttga ggccgccgtg ccctacgcct
     6661 ccggcctggc tacggaacgt gaccagatga tcgtccgcga gatgagcgac aaccatctga
     6721 agtggtcggc cttcctccac gacgccgcca cgcagaccgt ccgcgcccaa gaggtccgca
     6781 tcggcacgga ggacggcttc cggatgctgc ccaacctcat gcgctatgcc catcccgccg
     6841 aactcgacct gatggcccag ctcgccgggc tgcgcctgga acgccggacc gcggactggg
     6901 cggggaatcc cttcacctcg accagcacgc accatgtgtc cgtatatagt cacctgccag
     6961 ccgaacccgc cctgccgacc ggagcgcccg catgacgaac gtcctcccgc agctcctccc
     7021 agaagctttc ggcacagcgg aaaccgccca cgtatccctc gtcgccgatc gacgcggcac
     7081 cgccttgtgg caggtgcacc tggacgacgg cagccgctac gcgctgaagg cgaccaccgc
     7141 gtgcacggac ccacagggcc atgtcgactc cgagcacctg gcactggtcg aggcagagct
     7201 gctgatggcc ctggagcgcg ccggtgtgct ccgccacctc taccgggcgc acggcgacct
     7261 gccggacggc accggtacct ggctgacgct gcgctggctg cccggcgagg aggcggagac
     7321 cgcctacggc aagctccgta cgacgcccga cgaccggacc gccgcccggt atgcggcggc
     7381 gatggccggt gcggtggccg acctgcacga ggcgggatgg acacacggcg acatgcagga
     7441 agtccacttc atcctggacg gcgacagcgc gcacctgctc gacttcgcga tggcccagcc
     7501 gcccgccggc atccggatcg ccgcccaccg tgcgccgtac cgaggggcct acgacttctt
     7561 catgtccccg gagctggccg ctcgccgcct cgccacgaag ccgtccgagc acctggagct
     7621 gaccacggcc tccgaggtgt ggtccctgtg cgcgacgatc tacgcgtgct ggaccggggt
     7681 gtacccgatc agcgagaagg acacgaagct cagcacgccg gacctccgcg ccgagcttgc
     7741 ccacggtcgg taccggccgc tgccgatggt ccggccctgg gcgttccccg ccttcgagga
     7801 catcatctcc acggggctgg tcatcgaccc gactgcccgg ccgaccgccc gcgaactcca
     7861 gcacatgttc caggaactgg tctgacggcg aactgccgtc accatcggcg ggagcagttg
     7921 cagctccagc ggtagcaggg aaggcacggc ccccccggcc aggaaagtcc tggccggggg
     7981 gctgctcgtc gggtcggagc ggactacatc gccaccggcc agctgtagga ctgggcctgt
     8041 gtccgccaca tggccgcgta ctccccgtcc aggtcgagca gggactcgtg ggtgccctcc
     8101 tcgatgagcc gaccgcggtc cagcacgacg atccggtcag catttcgggt cgagcccagc
     8161 cggtgggtaa tgaggatgac cgtccgcccg gcccccagcg tccggatctg ctcgtacatc
     8221 gcctcctcgg ctcgggggtc gagagcggaa gtcggctcgt cgcagatcag cacgggtgcg
     8281 tccttgcgga agaacgctcg cgcaccggcc aggcgctgcc actgtccgcc ggacaggtcc
     8341 cggccgcccc actgcgacgg cgcgaggttg gtgtccagcc cgtcggcaag ctgctcgatc
     8401 acctcgtcgg ccccggcgag ccgcgccgcc tccatcacgg cctggtcgtc gccctcgccc
     8461 tgcccgaggg tgatgttctc gcgcgcagcc acgggccacc gggcaatgtc ctgcggcagc
     8521 atcgccaact tcgcccacac cgtctccggg tcgacggtcg ccaggtcgac gccgccccac
     8581 tcgaccacac cctgagtcgg ctcgtacaag cccgccagca gcttggccag cgtcgacttc
     8641 cccgacccgt tcgcgccgac gatcgccagg gtctcgccag gccgtacggt cacgctcacc
     8701 ccgtccaggg cgggggcagt gtggccgggg tatcggaagg tgatgtcctt ggcccggatc
     8761 acgtccggct gcgtcggaac cgtgccggtg aagtccctgg cccgtgtccg ccgttctgcg
     8821 tccgcgacga agtcggccca gtcgccgagg tagagaccgg tcttgtaggt ggtgttcatc
     8881 ccggttacga gcccgacgag catcacgcgg ctggcctgca ctgccactac cgcagtgcct
     8941 gccgccgcca gcggcacccg ccctgagatc accagagccg cgagcgccgc gtacaccagc
     9001 atcgccgccg caccggccag cgcgtcgccc agcagctggt agcggccggt ctcccgaccc
     9061 acccgggccg cgtgcgcggt cagccgctcg gtcacctccg agaaccggct cagcagccag
     9121 ggccgcatcg tcgcggcacg cacgtccagc gcggtcggcc gcccggcagt gttgtagatg
     9181 agggtgtgcc gcagccgtcg atcggccagg gtatggcgct cggcacggta tgccgagcgg
     9241 gccgcctgca ccgccgccgc cgcgcggggg accactgcca gaagaagcag aggaagaagg
     9301 atggggtgga gggcggcgag gatgccggca gaggcgagca gcccgaccag ggcagtgctg
     9361 acggcggtga gcgcgtcgat catcaaatgg gtgtccttcg aggctctgtt cgcggcctcg
     9421 ctctggtcgc accaggctgg gtcgtcgtac gaggcgaggg ggacgctggt ggcggcgtgg
     9481 aggtagcgga gttcggcgat ggcgtcgacg cgcggcccga tccgggcggt ggtggccagg
     9541 gtggcggcgg cgatcaggga gcgggcggcg gcggccgtca tgatggcgat gatcgcgggg
     9601 agcgcggcgt gcagccggtc ggcggccagg ccggagccga acagcgggga gagcgcgccc
     9661 ttggtggcgt acaggccgat cgcggtgacg atgccggtgc cgacctggag cagcgcggtg
     9721 agcagcagcg cgggccggtc ggcctgccag gccaggcgca gggccgtggc cgacagggct
     9781 ggcaggcgcc gggccatcgt ggcgaaggag tcgtcgaggg cgctgtcgtg gcgttcggcg
     9841 ctgaccgcgt actgcgggat gacgtccgtg gcggcggggc gggcgcgccg ccgccacggc
     9901 actcgggggg cgggatcgga ctgttggtgg tgcgttgtct tcataccggg cgcaacggtt
     9961 cacccgtacg ggtggttgtg gtggcgaagg gtggcgaatt tcagttcgac gattccaccg
    10021 tgagagcagc ccggtacggc cacacgcggt cggcgggttc ctgcccgtgt acggcgtcgg
    10081 cggtggcgat ccaggcgtgc gcgccctgcg gtacgaaccg ggcgcccagt acccacgcca
    10141 cccggcggcc ggtcattgcg gcggccaggt aggcagccag cgactcctcc aggcacgccg
    10201 ctctgccggg ccaccatccg actgcccggc gtaccgccgc gcacaccgcg tcggcctctt
    10261 cctgcgaggc ggcccggccc ggcagacgac ccgcgagccg ggcggcacgc accaccagcc
    10321 gtacgggaag gcagcgcagc agcaccagcg ccgtccccag ccccacgtgc ccggccgcac
    10381 gcactactgg gcgagattgg gcaacggtat cgacgtaccg gacctcgggg gccctgctcg
    10441 tcggcgggtg gggcgcggcg gtgaacaagc cctcggcgtc gagctggcca gccagagcat
    10501 tcatgtcggc gcgcacccgg tccgggtcga tgccgcgctg cgcccagtag gtgaccagtt
    10561 cctccacggc ctgttctcgc ggtgtgccgg agacgacctt ccgccacagt ccggccccaa
    10621 ccgggtcgag gaaccgccac tttccacggg tggtccccag gtccatcagg gccaccccgt
    10681 ccccggtgtc ggcggcgaac acccgcgcgg ccgtcacgct gccaccctgg gcgcgtccgt
    10741 ccgctcccac cacgcggagc ggccgagcgg gagcagagcc agccagagct cggccgccac
    10801 caggccgtgc agcgccgcca gcggtatcgt ctccccgcga acgccggcgt cgagcgcgcc
    10861 catcacctgg cgccggtcga ggaggtcagc ctgtacgagg atggacccgg tcaagatccg
    10921 gcggaccgcc ggggcgtgtg cccgtagccc gtcgtacagg ctgccggtga acggcgtctt
    10981 cgtgcgccgc tccagcagca cgtccggcac gaggccggtg aacgccgccc cggcgagcgg
    11041 cttgaacgcg cccggccgcg accgctccca cccgggtatc gcgtggcaca cgtcgacgac
    11101 acggttgtcg agcagcgggg cgtgcacggg cagatcccac agggtgcgcg acatctggtc
    11161 aaaggtcgag tgcccatcac ccatcagctc cagggccagc cgctcgtgca gtcgccccgg
    11221 tgtctcgcgc cggtccgcgc tggtggctcg cgcgccgacc agaccggcca cgagcgagcg
    11281 acccgaccgg gtcagccacg gcagggcccc gccgacaccg gaccacgcca gaatgcgtgc
    11341 tgctcctgct gggccgtccg tacggcctgc ctccactcgg tcggcaagca cctccagcgc
    11401 gtgcgggtag ggggtagcga tcgtgcgggc ggcctgggcc agcagttcgg tgcccgaggc
    11461 gcgccgggcc cgggccagcg cggctacgcg ccgccaggcc gccgcccgct gcccggcccg
    11521 gaactgatcg aggggcatcg atccgacggc gtccagcacg tcgtccccac ctcgtccggt
    11581 caggtgcagc cgcgatccgc tcagcaccgg ctctgcgagc tgcacccgct tcatctccag
    11641 cagccccagg ctgtaggtgg gggtgtcggt cagtggcagg aggtgcggat cgtccagacc
    11701 gccgaagtgc cgcaccgccc ccgtgccgcc ctccaccacc tgatggcgga cgcccggcag
    11761 ttcggcggcc acctgtcggg cgtagcgcac atcgtcctcg tccttcatcc gggcgtcggt
    11821 gtaggtcacc gcgagcagcc gcgtgctcat cgcggcgacg gacgcaacga cgctgctgtc
    11881 catcccgccg gacaggtccg ccgagatgag gccccccgtc atcgtccgcc gttgcaccgc
    11941 ctcgaccacg gcatcgcgtg cgagcggcgc ggccttgtcg aacgccagcc ggcccaccgg
    12001 cggcgcgaca ggttccgtac gcggcgactg tccctcttcg aggaccaagg cgtggccggg
    12061 ccgtacccgc cgcaccccgt ggaagtgcga cgcgccgtcg agcacatcca ccccctggag
    12121 catcatctgc ccgagcagca ccgcagggtc cgcctcgtat ccgccgagcg aggccagcgg
    12181 tgccgccgcc gttccccaca gcactcggtc ggcgaaccgc atccagaaca cctggaccgt
    12241 tcctgcccga tcccccatga cgcgccagac ccggccggtg cgcaccagca cgagagccac
    12301 gcccggtaac cgggccgccg ccacccagtc gccgcgcgcc gccgcggcgg cggcccgttc
    12361 cagctcgacc accgaggcca ggcagcttcc ggccaccacc accgtgccgt ccccgaaact
    12421 gcctcgccgg atctcgtccg ccctgaactc gttcgcccag accccaaggc cgcccacacc
    12481 ggctacctcg gccgccccct tcggccgcca ccccaacccg gccgccgccg tggttcccat
    12541 gatgaaccgc atcgccgtcc tcctctctac tcgtactcga caaagggagg cgcccagcac
    12601 gcacggccga tggccgttcg tcctgggcgc cccatcaggt cagcaggccc gcgtcaggcc
    12661 gccgggtcag ctccagtact gggtgtcgtc ggcgttgtcg ttgcccgcgg agccgagcgt
    12721 cacctcgacg acggtgccga gctcgctgac cgcgggggtg gtgtagatcc agtcgttcgc
    12781 gttctcgatc atgatcgatc ccttcaacta cctgaggtag atggtcggtt ggccccgccc
    12841 tgctctcgct gggcggtggt cacattcaac ggccgatcag atctggtcgg gagtgccgga
    12901 aaggggtgcc aattccttgc tggggtgcca ggttggggcc agaaggggtg ccaaatacgc
    12961 accgacattg accgcatagg gaaggggcat cgatggtgac tccagacggg atcggtcagt
    13021 tactccgcga ggtgcgcgag agagccggac ggtcacgggc cgagcaggcc agacgcctca
    13081 ctgctgctga ccgccactgc accgaggaga acgtgaagcg gtgggagctg gagacgaggc
    13141 tgccgtctcc ggtgtggtac cccgcgatcg tgtcggtcta cgggctcggg gaagaacagg
    13201 taagaggtgc cgtcgctgct tcgcgttggt accgcaagca gcggaaggag agtgaggatg
    13261 tggagcgcag gaagttcctg ggcggggcag ccgccaccgt aggcaccgtg gccttgcccg
    13321 gcatcgccca ggcccgcgag cacatcgaca gcgccctggc ccccaccggt gaggccgacg
    13381 tcgcctactt cgagggcgtc ttcgagcggc accggggcgg ctacgccggc cgcacccccg
    13441 acgccgtgct cggcctgatg gaacaggacc tcgaagagct ttccgtcgcg ctgcgccgca
    13501 cgaggcacgc gggtgaccgg agcgatttag tccgtgccgc tgctgggatc actgggctcg
    13561 tcgcgatcat ccagcacgat cgcggtgacc gggcggatgc gcaccgatgg ttcgccatcg
    13621 ccgggaaggt cgcccgcgag tccggcgacc gccgcaccct ttcctgggtg ctcgcccgcc
    13681 gcgcaatggt gccccttaac tacggtgctc cccgccaggc cgccgagtac gcgcaggccg
    13741 cccgccaggc cgcaggccgc accccgaccg gagccgccgc actggccagc gccgtgcacg
    13801 ctcgcgcgct cgctgccctt aacgacgtca acggcgcacg caaggccatc gccagcactg
    13861 agtccctact ccagaggatc gatggcgagg agaccgccga cacctggttc ggctaccccg
    13921 gccagaagca tgaggtgcac ctttcccagg cgtacaccct cctcggtgac accaaagccg
    13981 cttaccgcca ccaggacgcc gccctcgccc tcacccgctc cccgtcggtg atgacccgcg
    14041 ctctcctcgc tctggacacc gccgcctgcc tgcgcactga cggcgaccat cgcgaggcgg
    14101 ccagcatggc tgccggggtg tggggccgcc ttcccgtcga gcatcgcagc ggtctcatcc
    14161 gtgcccgcgc gacagttctc ctcgaccgtc tcgacggggc tgcccacgaa cacctccggg
    14221 aggcgctggc tagttgaccg aacacctggt ggctctggaa tcggccaact gagtctcgcc
    14281 cggtccgctg tccgacggtc gctctagcgt cggctgaatg gatcagacga acgtcacagc
    14341 cgccgcccgg cgggtggtaa tcaccacgcg gggcgccggg gtcgacattg atatcgacgg
    14401 caagcgcatc gagccgaacg ccgtgaaggc gtactccgtc agccacctcg ccggggagca
    14461 ccccgaagtg ctgctgcacg tcgcggaccg caacgacgtc cagtggtccg ggaccgcccg
    14521 cgtagcggtg accgacctcc ccgaccccgg gccggctgcc gccgtgttcc tcgacgcgat
    14581 cgatccggag gcgttggagc gagccgcgct ggctcggccc gacctcggaa ccgagccggg
    14641 ctcgctgacg aaggcgatgc tcacccagct aggggagtgg gctcgtggcc tttgacgtgg
    14701 acggggcccg tcgcgttgtc ggccgcatcc tggacgacaa gctggaggtg tggcgggacg
    14761 acgcgggccg tacggacgac gtgctggacg aagccacggg caggttggtg ccgcccgcgc
    14821 cggacgagga gctggtctgg gacgggctcg gcgcggtgat gccgctcggt cgccccgcca
    14881 tcacgaagcc ggtcggcggg tcggtcgccg tggagccgcc gaccaccgac tatcaggccg
    14941 tgctgccgat cggcgctccg gcgctccggc gcgacgacgt ggttcgtgtc gccggttcgg
    15001 tccggcccgg tgggccccgc gatcctcagc tggtcggtcg ccggttccgg ttctccgacg
    15061 agacggtggg cacctacagc gtggtgcgca tcgtccgggt ccaggtgatc gactgatggc
    15121 cctggcaaac acgcatccca acgcccaccc ggacgcgacc gcgttccgtg atccgatcgc
    15181 gctggccgcc gcgctggccc ggatgggccc ggcgacccgt gcccggacgc ggacgatcac
    15241 gcggcaccac gccatgctgc tgcgggtccg tattcagcgg aatgcgagcg ggcggccggg
    15301 cccgaacgtg atcaccggac agtaccgggc ctcgtgggac gtacggatgc gcaccggggg
    15361 cggtgaggtc accgccgagg tgttctccga cgcgccgcag tcgaggcggc tggagtacgg
    15421 cttcgtcggc gtggactcga tcgggcggca ctaccggcag ccgccgttcc cgcacgtcga
    15481 gcccgcgttc cggcagaccg agcccgactt cgtgcaggcc ctggcggacg gagtgctgcc
    15541 gtgaccgccc ggctgccggt gactcgcgcg ctcgccgcac tcgtggagaa ggccaccggc
    15601 cgcccgtgcg gaacaggcga actcccgcgc gtcgagggga agtccggctg ggtgcccgcg
    15661 tcccccccgt acacgatcct cgactcgctg cccggcgagt tcggcgggcc gccgctgtgg
    15721 gactggcacg cggacgcagc ctggtcctac caggtcacct cggtcgggga gcggggcgat
    15781 caggtcgagt ggctggccga ccgcgtacgc gccggcgtcg tcggccggac cgacggacac
    15841 tgggcctatg acctgcatgt tcccgaagcc cgtgtcatcg accgggagtt gacgtacgac
    15901 gccggagggg agccctcggt gtcggcggca ggcgctatcg tgtcctacgt gcaacgggtc
    15961 acgatcaccg tgacaccagc atgaagaaac gattcttctg atcctcaccg cggaggcccg
    16021 cgcggacgct gagccccacc aggccaggcg aacccccttt gatcatcaag gggcagggcc
    16081 tcggcacggg acgctgcccc agaagtggga gcggacctgt gtccacgagc acgaagaaga
    16141 acatccagac ccgatttctg cggcgcggca tctccaagat cctctgggtg ccggatctca
    16201 acgatccgaa gtaccccagc cgtcgggaga tcaccaaggc gttcgtcctg accgatgccg
    16261 tctcggacat cgagggctgg gccctggaaa atgatcccat tgagacgccg gatatgggga
    16321 gcacgttcaa ctcctctatc ccgggcaacg acaaggccga gaacagctcc ctgacgttct
    16381 acgaggaccg gttctccgac gccatcgagc agcagctccc caagggcgcc aagggttacg
    16441 tcgtcctgct ccgcaagggt gacctgcccg gttcgcgctc ggttgacgtc ttccccgtcc
    16501 aggtcgccac ccgagctgcg tcgtacagca ccagtaacga ggcggcaaag tttcaggtca
    16561 cctttacggt catcgacgag ccgtcgctcg accgcccggt gccgcaggcg caggcccggc
    16621 ccctgccgga cgaggactgc gagaccgatc acgatcacgg ccaccacgac ggtgaccacg
    16681 tcgacgtgac ggtggtcagc accaccaaga cgaagaccga gaccgaggcg acggtccgcg
    16741 agcacgacgc tgacgagggc tgatcgtgtc gcgccccgca caggcaaagc gccccgcccc
    16801 ctccgccagc ccggcggagg gggcctgggc ggccaagatg gagcgtctcc gccgtcggcg
    16861 caaggtgcag aatcggctcc gcgtctgcga cgacaacgag ctgcgccagc ggtacgacga
    16921 ggccgaacag gccgcgcgcc gtgcccggtt cgttgccgag gccaaccccg gtgacgagct
    16981 ggccgagcgc caggccgccg acgccgacac ggcgcgcgac caggcccttg ccgcactcga
    17041 tgccgcgtca gagttcctgg ccttccgcgc gctgcctcga ccggtgctgg aggagctgat
    17101 ctccgagcac ccgcctaccg aacagcaggt ggaagagggg gcgatcttca acgccgtcac
    17161 cttccccggc gccctggtgg cggcggcctc cgtggacggt atgagccgcg aggaggccga
    17221 ggagctgctg aacggctggt cggcgccgga cgcaaacgcc ctgtgggatg cggcctggca
    17281 ggtccagcag gagagccggg tcgagctggg aaaagactga gccgcgacgc cggtctgcgc
    17341 gcggagctgg agctgtgcga gaagttccag atcccgcact cgcagttcct cggcggcgac
    17401 ggccgttggt ccgaccttga ccgggcgaag gcgttggcct gggcggagtg gcagcggtcg
    17461 gtgtgcccgg agtgccgtac gcggctggag gagtgggacc gcacccgcgg cggtgacccg
    17521 cacgcgtacg tcaccgacac cctgcgctgc cccggctgcg agctgatcga gcaggagcgc
    17581 gatcacgtcc cgcaggaccg gtccggctac ggcgtgaaga tccagctcct cccgcgcgag
    17641 cagtacgagt cgcgctcctg attcaccccg cacgtatgta aggaggccgc cagcggtggc
    17701 cgggttcacc ctcacggtcg cgatgcgcgc cgaggtccgc gacctgatcg cgggaacccg
    17761 tgctgcctcc gcacagatgc ggacccttgg ggaccggacc gatgccgcga accggtccct
    17821 ggcccggctg gatgccaatg gggcacgtct cgcttcgcag ttcgccgcgc tgaatcgttc
    17881 cgcccgcggt gccgtcggtg agctgaaccg gatcaccgcc cgcgctgggg ccgctcgcgc
    17941 tgcgctgcgc tccgccgggg acgacggggc ccggtcgatg tcccggctcc agcgggcgac
    18001 cgccggtgcc ggtcggcgcg ggacgtcggc gacgaacatg ctcgcgggcg gcgctcttgt
    18061 cctcggcacc ggggagatca tcgaggaggg caaccgctac cagcggcaga tgaacctctt
    18121 ccgcgcggtg accgacgcga ccgccggaca gatgcagcgg gccggcgtag tcgcccgcga
    18181 actaggcaac gacctgacgc tgcccacctc gacctcggcg gacgccgccg agggcatggt
    18241 cgagctgtcg aaggccggtt tccgtgcgga ccagtcgatc gacgccgtac gcgcatcgct
    18301 ccagctcgca gcggcggccg acgtcaacgc tgccacgtca gccaagtatt tgggtgacat
    18361 catggatcag tacggccttg gtgctgatca ggcgtcccgc gcggccgaca ccctcgccgc
    18421 cacggcgaac aacgcgtcgg gctcgatcac cgacatctac tactcgatgc ggtacgcggg
    18481 cccggtcgcg aacgcgctcg gcgtcaccct ccaggacacg gctgcggccg tcggaatgct
    18541 cggtaaatct ggcattttgg ggcaaacggc gggaaccagc ctgcgcggga tcttcgccaa
    18601 cctcgccgcg ccgacgccga tcatgaagaa cgcgttgcgc gatctcggga tcgaagcctg
    18661 ggatgccgag ggccgattca ggggcctgcg cacggtgatc gacggcctgt ccgaggccga
    18721 acacagcatg aatcagcagg acttcgtggc cggcgtcacc cgtgctttcg gcaagcctgc
    18781 gctcagtggc gcggtggcgc tcgctcatca gggaaccgag agcttcgacg cgttgtcgat
    18841 ggcggtcgag cagaccggct cggcggcgga catcaccgct tcacgtggtg agggtctggc
    18901 cggtgcgatg acgcaactgc gtacgcaggc gcgccagacc ggcattgccc tgtacgacgg
    18961 catggcgccc ggcctggaat gggtgacccg tctgctcacc cgcggcatgt ccggggccac
    19021 gccgtacttg acccaggcga tcgagtacgg caacgacctc gccaccctgt tcggcccaga
    19081 gctgaaggcg cagacgaagg acgggctcag cggcctcatc gaggaggccc agcagctcgt
    19141 tggtccgctc aaggacattg gcgagcactc cctcgccacc ggtctcaact tgctgatcaa
    19201 cgccgggcgc acgctcgggg acgtcctgga gaacgccgcc gatggcgcgg agccgatcct
    19261 ggaggccgtc tccgggctcg gggaggaagg cggcgcggcg gccgggacgc tcgacatcat
    19321 cgccaccgtc ggcaacatcg cgatggacgc ggtctccggc ctgtcgatgg tgctcgtacc
    19381 gatcggtcat gccgtcggcg gcctggtgag tgcgttcggc gcgctgccgg gaccgatcca
    19441 gtccgccgct ttggccatgt tgctgttccg ccgcgcccag ccggcgctga cgaacatggc
    19501 gaccaccatg accgggcccg tccgctcggg catcagctcg ttcaaccagc agatgcgcgt
    19561 gcagcagtcc ttggccgccg cgtccggtgt cgccctgtcc cgatacgggg cggcatgggc
    19621 tgctgtccag gcgcgcgtcg ggtttctcgg caacatgacc tcggcgttcc gcagcgcgaa
    19681 cggtgccgga actacgttcg tgggcacgct caacggcgtt ggcagggcgg ccggatcggg
    19741 gctgcgctcg gcgctcggcg gtgtgaccaa cgcgctcggc gggccgttcg gcgtcgtgat
    19801 ggccggggtg tcggtgggcc tggggctgct cgcttcacgg cagcagaagg cagcccaagc
    19861 agcagccgag caccagcagc gagtctccac gcttacgtcc gcgctgcgtg agtccggggg
    19921 acagatcgac agcaacgtac gcaatgcggc ggcgcagtcg ctgctggaca cgaagaccga
    19981 acagggcgag ctcgccaagg tcatggacca ggccggagta ccgctcgcct cgctcaccga
    20041 cgcctacctc gggcagggca cgtcgctgga cgcgctgcag aagcagctcc aggccacggc
    20101 cgacaagcac aaggtgtgga agaacgtcgc cgggggcaag gcgaccgtcc aggactactc
    20161 cgaggtcggc cagcagtaca aggacgccgc tgatgcactc gggtcggtca agggcgagat
    20221 gtccggggcg ctgaagaacg ccaaggacct ggccaaggcc accaagggcg ccgcagacgg
    20281 cacctcggcc tacgaccggt tgaaggcggc cgtcggcggc ctggccgacc agaccgccga
    20341 cgccgacacc cgcacccggt ccctgaagtc cgcgcttgac ctgctgtcgg gcggccagat
    20401 ttctctccag gccgccgagg ccaaggtgaa ctcggccgtc ctcgacctgg aggacggcag
    20461 caagaacgtc gaccgcagtc aggggtacgg cggtaagcag ctcgtcaacg aggacaagac
    20521 cctcaacacc accacccgga acgggcaggg gctctacacc cagctcaccg cgctctccga
    20581 cgcggcggcc gacgcctccg tggccacctt cgacctggcc cagcgcaacg gcgaggacct
    20641 gccggccgcg ctcgcgaagg cccgcgagca gatgagccgg gcccggtccg aggcgatcca
    20701 ggccgcccgc ggctacgggc tgaccaaggc ccaagccgaa ggcgtcgcgg acagcctcgg
    20761 cctgctgccg tcgaaggtgt ccctgctgct ccagaccaag ggcatggaca gcaccttggc
    20821 gaacctcatc gcggtccagg cggagttcca gcggctgccg aacgccaaga cgatcaaggt
    20881 tgactcgctg tccgacgggg cgcagaagaa gctgaggagc ttgggcttca ccgtgaagac
    20941 ggtgcccggc acccggcaga tcaagatcag cgcgccgacc gccggggcga agaagaacct
    21001 cgacaccctg atcgacaagc tcggccgcac cccgaacagc aagaacgtga aggtgtccgc
    21061 gccgacagcc gcagcgatca agagcctgga aggtgtgcag gcgaagatcc gcgcgacgcc
    21121 cggcgcgaag tccgtcgtcg tacgtgcgcc gacggccgag gcccgcaagc agttggaggc
    21181 gctgggtttc aagatcgaga aggtccccgg ctcgaagaac gtgaaggtca cgctgcccac
    21241 gggcgggccg cgtaaggccg ctgactccat ccaggcgcgc atcaacgcct tgcgtggcaa
    21301 ggaagtcacg gtcaccactc ggcacgtcac gatcttcgac cagctccggc agtccaacag
    21361 cgacaccgca gacgccatcc gacgccaggc tgaggcgcag gcccgcgctg ccaagaagca
    21421 cgcggacggc gcggtcgtgg actacttcgc ggacggcggc gtcactgggg ggacgggccg
    21481 cgagcggcac gtcgcgcaga tcgccccggc cgggagctac cgcgtatggg gggagcgaga
    21541 gaccggcggg gaggcttacg tgcctctggc cgccgccaag cgcgagcgca gcaaggcgat
    21601 cgtggagacc gtggtcgacc ggttcggcgg caacgtcgag tggtacgccg acggcggcgt
    21661 ccggaacgcc cgcggccgcg actacagccc gacgctcgcc agctccttca agagcgcccg
    21721 cagcgttgcg gctatggcgg gcgtcgtccg ctccttcgac ctgcgcaccg gcagcgaccg
    21781 tgcccgcacc cgcgtggtcg atgcccgcgc cggcggccgg gttcaggtcg tcgtcgtgcg
    21841 cgagcagcag ccgctgatcg gctccatgcc ggtcagcgtc tctgacagct ccgccacccc
    21901 cgagcagatc ggcaacgaga tgatgcgcac cctgcgcaac gcgcagcggg gcgggagagt
    21961 gtgatgacca cagcaccgaa caagaacccc gaactggccc cgtttcagta cgagatcggc
    22021 ggcgttgtcc tcggcaccgg cagtctcgtc ccggtcggga acatcgaagg tctgggctcc
    22081 ccggccaccc ggtcgcagga tgccgacagc gccaacggcg atggcaccgc gcccggccgc
    22141 gacttctacg gcccgcgccc cctgcggttc gaggcgggca tcaagacgcc cggcgacccg
    22201 gtgaaggccg ccgagatcct cgcccggctg gaacgggccc tcgacgaccc cgccgcccgg
    22261 accatcccgg acggccgcca cgttctgcgc ggccggtggc ccggacactc aacgcgtcgc
    22321 ctgtacgggc gacttcgccg catggaagcc accagcaccg ccactgccgt gcacgggtgg
    22381 atacccatcg acctggagtt cgtcggactg gacaacccgc gctggtacga cgacgagctg
    22441 tcgaagctga cgctcggcct cgaccaggcc gcccacgcgg acagcgacga ccgcaccgta
    22501 gacgaggcga tggaccgctc cgccgcctgc cgccgtcccg ctgacccgga gc
//
