LOCUS       NZ_LIVW01000001        22667 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02115 scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_LIVW01000001
VERSION     NZ_LIVW01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02115
  ORGANISM  Streptomyces sp. CB02115
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2387836)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2387836)
  AUTHORS   Yan,X., Ge,H., Hindra,F., Yang,D., Huang,T., Crnovcic,I. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905645.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:50:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,651
            CDSs (total)                      :: 7,572
            Genes (coding)                    :: 7,475
            CDSs (with protein)               :: 7,475
            Genes (RNA)                       :: 79
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 34 of 97
            Pseudo Genes (incomplete)         :: 79 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 23 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:09:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 713400
            Orig. end                         :: 736067
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LIVW01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22667
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22667
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22667
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12667](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12667)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    606..620
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     misc_feature    complement(667..682)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.37"
                     /tool="antismash"
     gene            792..1274
                     /locus_tag="AMK28_RS03125"
                     /old_locus_tag="AMK28_03085"
     CDS             792..1274
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446843.1"
                     /locus_tag="AMK28_RS03125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03085"
                     /product="ATP-binding protein"
                     /protein_id="WP_073740102.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARAALLIAAGAAPVVGAAGAASAADLPATPDLGGLT
                     ALDGAGLGDTVDSAVQQGTQAAGDTGGRLVGTALPAAGKTVGKSAGVAVPAAQETAGQA
                     AGNAGQAVGGVAEAAGGGLPTDALGGGLPTDALGGGLPTDSLAKGGLPLGGLPIGG"
     gene            complement(1381..2475)
                     /locus_tag="AMK28_RS03130"
                     /old_locus_tag="AMK28_03090"
     CDS             complement(1381..2475)
                     /EC_number="2.6.1.17"
                     /EC_number="2.6.1.79"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     3.5e-45. Score: 146.6. Matches aSDomain:
                     nrpspksdomains_AMK28_RS03130_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="AMK28_RS03130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03090"
                     /product="bifunctional succinyldiaminopimelate
                     transaminase/glutamate-prephenate aminotransferase"
                     /protein_id="WP_073740103.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-43, bitscore:
                     146.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDKLAPYKSTAQAHPDGIVDLSVGTPVDPVPEL
                     IQRALVAAADSPGYPTVWGTEALRDALTGWVERRLGAVGVTHANVLPVVGSKELVAWLP
                     TQLGLGAGDKVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPTGLKLLWLNSPSNPTG
                     KVLSKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYDGVVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTPAPVQAAAVAALGDDVHVSEQRAR
                     YADRRLALRAALQAHGFRIEHSEASLYLWATRDEPCWETVAYLAQLGILVAPGDFYGPA
                     GARFVRVAFTATDERVAAAVKRLS"
     aSDomain        complement(1387..2388)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AMK28_RS03130_Aminotran_1_2.1"
                     /evalue="3.50E-45"
                     /label="AMK28_RS03130_Aminotran_1_2.1"
                     /locus_tag="AMK28_RS03130"
                     /protein_end="363"
                     /protein_start="29"
                     /score="146.6"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPELIQRALVAAADSPGYPTVWGTEALRDALTG
                     WVERRLGAVGVTHANVLPVVGSKELVAWLPTQLGLGAGDKVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPTGLKLLWLNSPSNPTGKVLSKDELTRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGGHYDGVVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTPAPVQAAAVAALGDDVHVSEQRARYADRRLALRAALQAHGFRIEHSEASLYLW
                     ATRDEPCWETVAYLAQLGILVAPGDFYGPAGARFVRVAFTATDERVAAAVKRL"
     gene            complement(2643..2963)
                     /gene="fdxA"
                     /locus_tag="AMK28_RS03135"
                     /old_locus_tag="AMK28_03095"
     CDS             complement(2643..2963)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="AMK28_RS03135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03095"
                     /product="ferredoxin"
                     /protein_id="WP_007446848.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFIAGLPPQ
                     NQ"
     gene            3081..4100
                     /locus_tag="AMK28_RS03140"
                     /old_locus_tag="AMK28_03100"
     CDS             3081..4100
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="AMK28_RS03140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03100"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073740104.1"
                     /transl_table=11
                     /translation="MEFTIGGRLEVRITPADVGKRVSVRRRTDGGGAGAEFTDVVGVLT
                     SWNSGVLSITRKSGESVHIVESSVVAGKVVPAAPARRRGPAASFGELAAVTARAWQPVE
                     SEALGDWRLRAAGGFTRRANSALPLGDPGLPVGEALGRVRDWYEERGLPAYVQTATGAE
                     GTQEPLCAELERHGWRREVSAEVRIAALAPVGDLEADVRAVRLTREPDAAWLARYQRFS
                     TPGPHVLRVLGSGPSVWFATVSGDTVGADADPDALPAAIGRCVVDGRWAGFMAVEVAPE
                     QRRRGLATTVMAALARRALDEGASAAWLQVEEDNEGARALYDGMGFAAHHRYHHYRSA"
     gene            4177..5058
                     /locus_tag="AMK28_RS03145"
                     /old_locus_tag="AMK28_03105"
     CDS             4177..5058
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="AMK28_RS03145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03105"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_050360576.1"
                     /transl_table=11
                     /translation="MSALDSGTAERRRQFAEEARSERPDLALLCLLLGAEAGPVGPAEV
                     RPVTPGEAVPDPYGIDAAQIELDRLAGLLPYGSRSPAAWASALAELLGGRCGFGGSSVD
                     YQRLDSSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDREHPVL
                     ADPFAGGAPLTGQDAELLVTGATGAALEPSMMTPARPLEIVLRILNNVRAWAAARPERT
                     DVALWAVELSLLLPSHPARLRFERAQLLVQRGEFLRGAAEMEEYAEILDGIEPTTAENI
                     RRKAHAARALLN"
     misc_feature    5230..5243
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     misc_feature    complement(5238..5255)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            5330..5935
                     /locus_tag="AMK28_RS03150"
                     /old_locus_tag="AMK28_03110"
     CDS             5330..5935
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="AMK28_RS03150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03110"
                     /product="response regulator transcription factor"
                     /protein_id="WP_050360577.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGTGRGIEVRTAEHGAIRAALSGPC
                     PDVLLTDLECPGALDVLDEVKTMTAPHGGPCPLAVLTRSDRPSGLRRAFEAGALGYIDK
                     YRPVDDLSEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSMAEGGDTVAGIAG
                     RLHLTPGTVRNYLAAAIRKSGARNRLDAIRRAKEAGWI"
     misc_feature    5750..5752
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5904..7772)
                     /locus_tag="AMK28_RS03155"
                     /old_locus_tag="AMK28_03115"
     CDS             complement(5904..7772)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061641.1"
                     /locus_tag="AMK28_RS03155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03115"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073741092.1"
                     /transl_table=11
                     /translation="MRRVGREARPFLRARTGVVLRLAGWSLLEFAQTFLGGFGVARALD
                     DGFLAGRPATGLLWLAVAAVAVLPSVPAARGVFGRLADLVEPLRDGLVRRAVSRALSGA
                     LDRSGDVSTRSLSQVTHQSEIARDGWAGLVLTLRSFVFTVAGAVTGLLALSPALLLIVL
                     PPLVLGSALFLGTLPPMAARQRDYLAADEAYAAHAGRLTASVRDIAAAGAAGRTVAESR
                     ALAEAQLAASRSLARWSGVRVLALAVCGRFPPLLLLLGAPWLLRNGLTPGALVGALTYL
                     TQALAPAVQALMTMLGTVGGRLVVVLDRFTDAPPPPAEDPPPTRDAAPPPRGTPVAELH
                     EVSFAYGPGAHPVLDRLSLTVGAGEHLAVVGPSGSGKSTLAAVLAGTERPTGGAVRWRG
                     RPVRPADATSVRVLLPQHAYVFSGSLRDNLRYLRPDARDREIAAMADALGLEALLSRLG
                     SLDAAVEPDRLSQGERQLVALGRAYLAAPPLLILDEATSRLDPAAETRVELAFGALPGA
                     LVVVAHRLSSARRAGRILVMDGPRTQCGTPDELLSSCALYRDLAGLWEPEDAGEPDGTR
                     EPEEPGEQDEAGGQEEAGEPEEPGGAVGIGRGKGRGIRSTPPPSPV"
     gene            complement(7976..9745)
                     /locus_tag="AMK28_RS03160"
                     /old_locus_tag="AMK28_03120"
     CDS             complement(7976..9745)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446857.1"
                     /locus_tag="AMK28_RS03160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03120"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073740105.1"
                     /transl_table=11
                     /translation="MRLHPRPGTESGTRRLARQYPAALLGLLLCSTGGALAALALPAAL
                     GHTVDRLVAGGPVPWSGLLLCAALTLAETGFDAAAAVTGTTTTARLTASLRTRTAARIL
                     AAEPRRALALPTGDLTARLTARTADAASAPVTAAGAVSGVLLPLGALVGLLLIDVWTAV
                     ALLLGAPLLVALLRAFTRRTADAGADYQRAQSLIAHRLTEALDGADTIRAARTGAREHR
                     RVLEPLTALAQHGRRTWTVYGRAVGRSGLLLPLLMLLVLAVAGLRLGTGAIGVGDLVAA
                     SRYASLAVGIGALTGALGALARSRAAARSLEPLLTLAPLPHRGLGPVPDAPGHLELRNV
                     GVEQDGGPLLTGVHLTVPGGTSLAVVGRSGSGKSVLAAVAGRLLDPDTGSVLLDGVPMD
                     GMEPARLRREVAYAFARPALPGTTVEDTIAYGPWTASPDAVRGAARAARADGFLALLPY
                     GYATPVADAPLSGGERQRLGLARAFAHPGRLMILDDALSSLDTVTEHHVRRALDERAGH
                     CTRVIVAHRLSSAARADRVAWLEDGRIRATGRHDELWSDPDYRAVFRTDVPAEDSVPAS
                     RTPVTPAAGAEAR"
     gene            complement(9825..9956)
                     /locus_tag="AMK28_RS03165"
                     /old_locus_tag="AMK28_03125"
     CDS             complement(9825..9956)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="AMK28_RS03165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03125"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003966507.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPAEDSFGELATGSQVSLLVCEYSSLSVVLCTP"
     CDS_motif       complement(9891..9956)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPAEDSFGELAT"
                     /locus_tag="AMK28_RS03165_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9825..9890)
                     /prepeptide="core"
                     /locus_tag="AMK28_RS03165_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="31.80"
                     /molecular_weight="2076.4"
                     /monoisotopic_mass="2075.1"
                     /core_sequence="GSQVSLLVCEYSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPAEDSFGELAT"
                     /leader_location="[9890:9956](-)"
                     /alternative_weights="2094.4"
                     /alternative_weights="2112.4"
                     /alternative_weights="2130.5"
                     /alternative_weights="2148.5"
     gene            complement(10001..12667)
                     /gene="lanKC"
                     /locus_tag="AMK28_RS03170"
                     /old_locus_tag="AMK28_03130"
     CDS             complement(10001..12667)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446862.1"
                     /locus_tag="AMK28_RS03170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03130"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_073740106.1"
                     /sec_met_domain="micKC (E-value: 1.9e-234, bitscore: 777.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.8e-12, bitscore: 43.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-08, bitscore:
                     30.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRSPGPGGAADEERSFYAPLRGAVPD
                     GWTRSRRGDWLAYSPDGLRLPPQGWKIHVSAALDNAASVLERVVAHCLEHRLAFKCVPN
                     AGLLALRNAKYADRAGSGKFITVYPPSDEAFPEVCTALTHLLEGEHGPYILSDLRCGNG
                     PVHTRYGAFAARFCSGPDGRPVPAVADPQGRLVPDDRGPSFRVPSWVTPPGFLMPHLEA
                     RAAVGLADLPYTVEKALHFSNGGGVYLGRDTRTGEQVVLKEARPYAGLAADGADAVARL
                     ERERAALEQLAGLDCVPAVRDVFEVGDHHFLVLQYIPGTTLNTVFARRFPLARQHPSPE
                     LLAEHAAWAAELYGQVERAVEAVHDRGIVISDLHMSNVMVDEENARIVLLDFEAASPAA
                     ERRRQIVANPAFVAPPDRRGADIDRYALACLRLALYLPLTTLFGIDRTKAAGLARDIAR
                     VFPVTEETLRPAVAEILRDTGEPVRRAAPASLQAPPPASVPAPAPVPDPGDWPRSRDAL
                     VRAITASCTPEREDRCFPGDIAQFATATGGQSFAYGAAGVLYALHETGAPPCDEAEEWL
                     LRHAKDPASGSPLGFYDGLTGIAWTLHRIGRTAEAADLLRIILDQPLQGLAPGLHNGYA
                     GIGLALDDLARTASATDAPALSAAAARCTALAVRALVDGPPSPRTGLLHGASGIALLLV
                     RRYATTGDAALLDLAATALRRDLERCRAGDDGELLVVEGKRLMPYLGSGSAGIAAVIDA
                     YLAHRPDPALEAAGRALLPAALSAFYVQPGLLRGSAGLLMHLAATPLCDEADRRRAIAR
                     HTDLLGSHALAYGDGLAFPGEQLMRLSMDLATGTAGALLALGAALGGSTGLPFLPAAPA
                     AHPGRASGPTDRPRQGS"
     misc_feature    12703..12715
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            complement(12878..13855)
                     /locus_tag="AMK28_RS03175"
                     /old_locus_tag="AMK28_03135"
     CDS             complement(12878..13855)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611151.1"
                     /locus_tag="AMK28_RS03175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03135"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_073740107.1"
                     /transl_table=11
                     /translation="MGWWQVGADTLANSRFVVSPLAEAVASLLVLERAGAAHPGERAWL
                     ETHLPAYRRWKADDPVSALVVGAALAPRWIADFLIPVPDPAPPGQAPPSFADELTPVRA
                     TPPDRARADLAEAVRGPLPAALDRDDLARRAADALEWVWTHTVLPDWPRRRRILEADVV
                     ARSAQLGRGGWVDALNGMRPGIRWLGDSRLQINTHDNPPRELDGAHLLFVPVTPYQSWV
                     CWDIPRRYGLVYPCSGALAEAGRIPVPAALGALIGPARAAVLLLLASPLSTTQLVALTG
                     QGLGSVGRHLRILLEAGLVRRRRAGRSVLYFRTEAGDVLVHGAG"
     gene            13980..15218
                     /locus_tag="AMK28_RS03180"
                     /old_locus_tag="AMK28_03140"
     CDS             13980..15218
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956279.1"
                     /locus_tag="AMK28_RS03180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03140"
                     /product="MFS transporter"
                     /protein_id="WP_073740108.1"
                     /transl_table=11
                     /translation="MRTYRELFRTPEFTPFFAAVSAQTAAQTATGLALGTLVYTRTGSP
                     LLSALAMFGPSLAQVAGALTLLSAADRLPPRAALTALALLSAGAACVQAAPGLPLWAAF
                     AVLLVVGAASSPGGGVRYGLLNEIVPREGFLIGRSVLNMTGGAMQICGFAVGGLLVTVF
                     SARGTLLIGAGLYVVAAAVTRFGLTPRPPRATGRPSVRETRRTNALLWSSTPRRYVFLA
                     LWVPNGLVVGAESLYVAYAPGHAGLLFAGGALGMLAGDMLVGRFVTARWRTRLGAPLRL
                     LLAAPYLLFALRPGLPLALAAVVLASVGFAASLLLQERLMALTPQELSGQALGLSSSGM
                     LAMQGVGAAVAGGIAQLTSPATGMAAVAGLSVAVTLALAPGLRDRSGGVGGRLPVADGS
                     PRASRTPRTEETT"
     gene            15215..15799
                     /locus_tag="AMK28_RS03185"
                     /old_locus_tag="AMK28_03145"
     CDS             15215..15799
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956278.1"
                     /locus_tag="AMK28_RS03185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03145"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_073740109.1"
                     /sec_met_domain="Mac (E-value: 1.5e-15, bitscore: 54.1,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNARPSQKEAMLSGELYIADDPELAAEAQHAAVLSERFNATSA
                     ADPEARRAALAELLGELGEGVEVRPPLRVDYGYRTTIGPRTFINFGAVLLDVARITIGA
                     DVQMGPNVQLLTPTHPIDPEPRRAKWEAAQPITIGDNVWLGGGVIICPGVTIGENTVVG
                     AGAVVTKDLPANVVAVGNPARVIRKIGETEA"
     gene            complement(15873..16376)
                     /locus_tag="AMK28_RS03190"
                     /old_locus_tag="AMK28_03150"
     CDS             complement(15873..16376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="AMK28_RS03190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03150"
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_073740110.1"
                     /transl_table=11
                     /translation="MSSPAGPERPPREADQIKVWFRFVPREGWLPYDTEGLWATRLGPD
                     TARVDNVPFFQDGVAEGETVRFRTDDEGVHWAVGRVAESGNCTVRVLPLPDGPLGRDAR
                     AVHERLAVFGLTGEVFSAEFPLVALTVPGGADLRGVKALLARGRDEGWWHFEVSCVTDA
                     WRAA"
     misc_feature    complement(16574..16591)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.51"
                     /tool="antismash"
     gene            16675..18450
                     /locus_tag="AMK28_RS03195"
                     /old_locus_tag="AMK28_03155"
     CDS             16675..18450
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379170.1"
                     /locus_tag="AMK28_RS03195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03155"
                     /product="coagulation factor 5/8 type domain-containing
                     protein"
                     /protein_id="WP_073740111.1"
                     /transl_table=11
                     /translation="MHAPPTAPRTRLRTRALGFAALAVAMLMSVPTAQTAFGEEVQAVP
                     GGGDLGPNVHVFDPSTPDIQGKVDEIFKKQESAQFGTDRYALMFKPGTYDDINAQIGFY
                     TQIAGLGLNPNDTTFNGDVTVDAGWFDGNATQNFWRSAENLTLNPVSGTNRWAVSQAAP
                     FRRMHVKGGLNLAPDGYGWASGGYIADSKIDGQVGPYSQQQWYTRDSSVGGWGNGVWNM
                     TFSGVEGAPANSFPEPPYTTLDTTPISREKPFLYLDGDDYKVFVPEKRENARGISWGNG
                     TPAGESIPLDQFYVVKEGADAATINAAVEQGLHLLFTPGVYHIDETINIDRADTVALGL
                     GLATIIPDNGVTAIKVGDVSGVKLAGLLVDAGPVNSETLIEVGPENASADHSANPTSLQ
                     DVFVRIGGAGPGKATTSIVVNSDDTIIDHTWVWRADHGEGWGWETNRADYGVRVNGDDV
                     LATGLFVEHFNKYDVEWYGERGRTIFFQNEKAYDAPNQAAIQNGDTKGYAAYRVDDSVE
                     QHEGWGMGSYCYYNVDPTIIQEHGFKAPVKPGVKFHSLIVVSLGGNGQYEHVINDVGSP
                     TSGPDTIPSQVVNFP"
     gene            complement(18526..19902)
                     /locus_tag="AMK28_RS03200"
                     /old_locus_tag="AMK28_03160"
     CDS             complement(18526..19902)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455451.1"
                     /locus_tag="AMK28_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03160"
                     /product="alpha-amylase family protein"
                     /protein_id="WP_073740112.1"
                     /sec_met_domain="Alpha-amylase (E-value: 5.9e-23, bitscore:
                     78.9, seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase_C (E-value: 5.9e-12,
                     bitscore: 42.8, seeds: 246, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSRAARATLAGLLAAGGLTVLAPWPSQATPPGEKTVTATLFEWK
                     YDAVATACTDTLGPAGYGYVEVSPATEHIQGDQWWTSYQPVSYKIAGRLGDRDSFAAMV
                     ESCHAAGVKVVADAVINHMAAGSGTGTGGTSYTKYDYPGTFQDQDFHTCRKDIADYGDR
                     GDVQNCELVGLADLDTGSDAVRTTIAAHLSDLRSLGVDGFRIDAAKHMSADDVAAIKGK
                     TGDPGFWVTEVIHGGGEAVQPEEYTSIGDVDEFRYGGHLKSAFQGGGLPGLKSIADGKL
                     AGASARTFVDNWDTERNGSTLTHKDGAAYTLANVFMLASPYGSPNVFSGYTWTDKDAGP
                     PNGGAADCGSGAWTCTHAQQAVTGMVGFHNAVAGAELTDWWDDGSSALAFARAGKGFVA
                     VNNGDAELNRTFTTTLPAGTYCNVVAAAPDSCDGNGTTVADDGTATITVPARGAVALHT
                     "
     misc_feature    complement(20040..20053)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.69"
                     /tool="antismash"
     misc_feature    20040..20054
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.57"
                     /tool="antismash"
     gene            complement(20221..22407)
                     /locus_tag="AMK28_RS03205"
                     /old_locus_tag="AMK28_03165"
     CDS             complement(20221..22407)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379171.1"
                     /locus_tag="AMK28_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AMK28_03165"
                     /product="hypothetical protein"
                     /protein_id="WP_198957859.1"
                     /transl_table=11
                     /translation="MSRETDSSSSGPQGRGGAAYPSGTPPYGSRQYPSLHPSQDGSDEN
                     PESVAPPRPEEPKTETTLTTRIRINIPGSRPIPPVVMRTPMAESDIAGGRSDAERTGAT
                     PRPGTPPPAPGAGPSDRSAGPNGAAPADRPRDGGPAADPAPAEKPGREKSGSDWFAPRK
                     TSATGPGAAAQGTGAPGAPGGAPSGPGGAQGPGTGGPGGPSAGGPGGGSDGDAGPSRPD
                     LPYFSDAPQSGGGPGTPGPGPGRSALDGYGTEPPGGGPRSTPGLGVRPPGPPGPSGPTT
                     GPVTGSSSLTPNLDGVPGLDGVPGLGGPGPMVPGVPGGVPPRMSDDTAILTPQAPASEP
                     GPGHVSGDTLTSGIPVVPSEPRAAFPGGPGIPGGPVAGGPQGGPGGPGGPGVPTPGPAA
                     PRPASQAAAPAPAKKGRSKLVLLGVAAVVLLGIAYGAGLLLNHSEVPKGTTVLGVDIGG
                     GTKEEAVTKLEAALGERAKTPLQLSVDGKEEKLDPEKAGLTLDSQETVRGAAGSDYNPV
                     SVIGSLFGGERPADPVIPVDEEKLGVALTDLAGVSGSSNDGTIRFEPNKAVAVPGKPGK
                     TLDAGQSLISVRDAYRAQVQTGQARLVELPVTTSEPTITQTELDRAMKEFAEPAMSGLI
                     TIKAGPKEIQFGPARSLPQILSMKPVDGRLVDVYDKQAIDKLLDGVFDGIMAVKGDGKE
                     HQVGADDVAQAMKTALAGKTPAERTVTIDLTGQG"
     misc_feature    22639..22655
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.55"
                     /tool="antismash"
ORIGIN
        1 gccgaggtgc cgggctattc gcgcctcccg ctgaccgtgg cagcgcagcg tgtgcagcgg
       61 agcgggttcc cgcaggcgta cgcgaagcac gagccggacg ccgcgctgct ggccgccgcg
      121 ctgaccgggc gcaggccggc cgcgctgaac tgcaccccgt cgacggccac ggcggacggt
      181 ccgggcgact ccgcccgggt gcgggccgag ctggtgcggg ccttcggcaa gggcgtgctg
      241 cccgacgcgg tggccgcggg cgcgtccgcc gcgtcgacgg tctcggtgcc cgttccggcg
      301 gccgcggcgc agtcggagga caaggccgag cagcgcggct gggagctggc gcactgggcc
      361 gtggcgcagt ccgaggccct gcggatcgag cgcgtgagct acgcggaccg ggtctgggac
      421 gccggttcgg gctggcagac ggaacgtgcg aagggtaagg aaacgggcac ggcggcggtc
      481 aggatccagg tcgttcagta gtacgccccg tcacccgtac ggaccctggg ggccatgtcc
      541 cccgatgttt tccgcgcgac tccccgcacc ttcgcggacc tgctccgatt cccttgccgc
      601 ccaagggaag tgacggttca tcggaccacg gcggtatgga tcgtttgccc gggttcttcc
      661 gctgcggata atcggacgca ttactcagtc tttacctttg cccaccgcaa cctccccctc
      721 ccccgaagcg gttgtcagtg cgtccgatca ccggacagac agattcgtgc accacccgct
      781 gaaggagcat catgtccctc cccctgaccc gtcggatcgc tcgtgccgcg ctgctgatcg
      841 ccgcaggcgc agcccccgtg gtcggtgcgg ccggcgccgc aagcgccgca gatctcccgg
      901 cgaccccgga cctcggcgga ctgaccgcgc tggacggcgc cggtctcggc gacaccgtgg
      961 acagcgccgt ccagcagggc acccaggcgg ccggcgacac cggcggccgg ctcgtcggca
     1021 cggcgctccc ggccgcgggc aagaccgtcg gcaagtccgc cggggtggcc gtcccggccg
     1081 cccaggagac ggccggccag gccgcgggca acgcgggcca ggccgtgggc ggcgtggccg
     1141 aggcagccgg cggcggcctg ccgaccgacg ccctgggcgg cggcctcccc acggacgcgc
     1201 tcggcggcgg tctgcccacc gactccctgg ccaagggcgg cctcccgctg ggcggcctgc
     1261 cgatcggcgg ctgatccacc gcggtaccga ccgacgcgcc gagggcctcg ggagtgcgca
     1321 ctcccgaggc cctcggcgcg tcggtcgccg tcgtggcggc ggccctgttc aggaaaggcg
     1381 tcaggacagg cgcttgaccg ccgcggccac ccgctcgtcg gtcgcggtga acgccacccg
     1441 gacgaaacgc gcgcccgccg ggccgtagaa gtcgccgggc gccaccagga tgcccagctg
     1501 cgcgaggtac gccacggtct cccagcacgg ctcgtcgcgg gtcgcccaca ggtagaggct
     1561 cgcctcgctg tgctcgatcc ggaagccgtg cgcctgaagc gccgcgcgca gggcgaggcg
     1621 ccggtccgcg tagcgggcgc gctgctcgga cacgtgcacg tcgtcgccga gcgcggcgac
     1681 ggcggcggcc tggacggggg cgggcgtcat catcccgccg tgcttgcgga tgagcagcag
     1741 ctcgcccagg acggccgcgt cacccgcgat gaacgcggcc cggtatccgg ccaggttgga
     1801 gcgcttggag agcgagtgga cggcgacgac gccgtcgtag tgaccgccgc agacgtcggg
     1861 gtggagcacc gataccggct cggcgtccca gcccagctcc aggtagcact cgtcactgaa
     1921 gaccagcacg ccgtgctcgc gcgcccaggc gacgatccgg gtcagctcgt ccttggacag
     1981 caccttgccg gtcgggttgg agggcgagtt gagccagagc agcttcagcc ccgtcgggtc
     2041 cagctcggtc gggtcgtcgt agacgacggg ctccgcgccg cagagccggg cgccgacctc
     2101 gtacgtcggg taggcgagcc gggggtaggc caccttgtcg cccgcgccga gcccgagctg
     2161 cgtcggcagc caggccacca gctccttgga accgacgacc ggcagcacgt tggcgtgggt
     2221 cacgccgacc gcgccgaggc gccgctccac ccagccggtg agcgcgtccc gcagggcctc
     2281 ggtaccccac accgtcggat agccggggct gtccgcggcg gcgacgagcg cccgctggat
     2341 gagctcgggg accgggtcga ccggggtgcc gaccgacagg tccacgatgc cgtccgggtg
     2401 ggcctgggcc gtcgacttgt agggcgcgag cttgtcccag gggaagaccg ggaggcggga
     2461 ggagactgcg gacacggcgc tctgctttct cgggtgttct cgttcgggcg gcggatagga
     2521 cgcgcggtga cggagcccgg cgggaccggg atccggtgac ggtcccggcg gtacggggaa
     2581 acgcctcggc cccgcacggt gacaagccgt acgggaccgg gccgcgcgcg tggtgccgcc
     2641 gcttactggt tctgcggagg cagtccggcg atgaacgcgt ggtcgcgctc gatgagaccg
     2701 agcttggaag caccgcccgg cgagccgagg tcgtcgaaga actcgacgtt cgccttgtag
     2761 tagtccttcc actcctccgg agtgtcgtcc tcgtagaaga tcgcctcgac cgggcacacc
     2821 ggctcacagg ctccgcagtc gacgcattcg tccgggtgga tgtacaagga ccgctggccc
     2881 tcgtagatgc agtcgacggg gcactcttcg atgcaggcct tgtccttcac gtcgacacaa
     2941 ggctgcgcga tgacgtaggt cacgctgtcg ttcctcctcg gtagggcgtt ggctctcgcg
     3001 cgggagcgcg gcgtcgtcga tgcccgcctc tagtatctcc gttctcgggc acgatccgaa
     3061 caggaggggc ggacagagct gtggaattca ccatcggcgg acggctggaa gtccgcatca
     3121 cacccgctga cgtgggcaaa cgcgtgtccg ttcgacggcg gacggacggc gggggtgcgg
     3181 gcgcggagtt caccgatgtg gtcggcgtgc tcacatcatg gaacagcggt gtgctctcga
     3241 tcacacgaaa gagcggggaa tccgtccaca tcgtggaatc ctccgtggtc gcgggcaagg
     3301 tcgtccccgc cgctccggcc cgccgtcgtg gccccgccgc ctccttcggg gaactggccg
     3361 ccgtcaccgc gcgcgcctgg cagcccgtgg agagcgaagc gctgggcgac tggcggctgc
     3421 gcgccgccgg gggcttcacg cggcgcgcca actccgcgct gccgctcggc gatccggggc
     3481 tgcccgtcgg cgaggcgctc ggacgggtcc gggactggta cgaggagcgg ggcctgcccg
     3541 cgtacgtcca gacggcgacc ggggccgagg gcacgcagga gccgctgtgc gcggagttgg
     3601 agcggcacgg ctggcggcgc gaggtctcgg cggaggtgcg gatcgccgcg ctggcgccgg
     3661 tcggtgacct ggaggcggat gtacgggcgg tccgcctgac ccgcgaaccg gacgcggcct
     3721 ggctcgcccg ctaccagcgc ttctccaccc ccggccccca tgtgctgcgg gtgctgggca
     3781 gcggcccttc ggtctggttc gccacggtgt cgggggacac cgtgggcgcg gacgcggatc
     3841 cggacgccct gccggccgcg atcgggcggt gtgtcgtgga cggacggtgg gcggggttca
     3901 tggccgtcga ggtcgctccg gagcagcgga ggcgcggcct cgccaccacg gtgatggccg
     3961 cgctggcgcg ccgggcgctg gacgagggcg cctcggcggc ctggctccag gtcgaggagg
     4021 acaatgaggg ggcgcgggcg ctgtacgacg gcatgggctt cgcggcccac caccgctacc
     4081 accactaccg ctcggcgtga cgggcaccgg tggcccccgc tccgggccct ccggtggatc
     4141 gacgcacagg agcagggaca gggacatggg tcgcatatga gcgcgctgga ttccggaacg
     4201 gccgagcggc ggcggcagtt cgccgaggag gcccggtccg agcggccgga cctcgccctc
     4261 ctgtgtctgc tgctgggcgc ggaggccgga ccggtgggcc cggccgaagt ccgcccggtg
     4321 actccggggg aggccgtccc cgacccgtac ggcatcgacg ccgcgcagat cgagctggac
     4381 cggctggcgg gactgctgcc gtacggctcc cgctcccccg ccgcctgggc ctcggcgctg
     4441 gccgaactgc tgggtggacg atgcgggttc ggcggatcct ccgtcgacta ccagcggctg
     4501 gactcctcgc tcctccagca ggtgctgcgg cgccgccggg gtctgccgat cctgttgtcg
     4561 gtcgtctgga tcgaggtcgc caggagggcg ggcgcaccgg tgtacggggt ggcgctgccc
     4621 ggccacttcg tggtcggttt cggcgatcgg gagcacccgg tgctggccga tccgttcgcc
     4681 gggggcgcgc cgctgaccgg tcaggacgcg gagctgctgg tcacgggggc gaccggggcg
     4741 gccctcgaac cgtcgatgat gacgcccgca cgccctctgg agatcgtgct gcggatcctg
     4801 aacaacgtcc gggcgtgggc ggcggcccgg cccgagcgca cggacgtggc cctgtgggcg
     4861 gtggagctgt cgctgctcct gccctcgcat ccggccaggc tccgcttcga gcgcgcccag
     4921 ctcctcgtcc agcgcggtga attcctgcgc ggggcggcgg agatggagga atatgcggag
     4981 atcctcgacg gaatcgagcc gacgacggcc gagaacatcc ggcgcaaggc ccacgccgcg
     5041 cgcgccctgc tgaactgaac cggccgtccg gcggggaatc cgcggaaacc ggccccgcca
     5101 gcggcccttc ggccgccccc gcggtggcga gacggatggg tccgtgggcg atgtgcgctc
     5161 ccgttttaca tccgaacgcc cccttccgcg cccaacgggc gcggtattcg gcccgtttgt
     5221 cgacgtacgc gaatgcccat gcgctcaact ggatacccgt caccggatgc gtacagcccg
     5281 tcgcattccg cgttgggcgg gccggaagag aaaagctgag ggcagactga tgacaaccgt
     5341 gctgctggtc cacaccgtgc cgttgtggcg cgcatcgctg gcgtcgctcc tcggcacggg
     5401 ccgggggata gaggtccgca ccgccgaaca cggtgcgata cgtgccgcgt tgagcgggcc
     5461 gtgtcccgat gtgctcctca ccgacctcga atgtccgggc gcgctggatg tcctcgacga
     5521 ggtgaagacg atgaccgcgc cgcacggcgg accctgtccg ctcgccgtgc tcacccgcag
     5581 cgatcggccg agcggcctgc ggcgggcgtt cgaggcgggg gcgctcggct acatcgacaa
     5641 gtaccgtccg gtggacgacc tttccgaggt gatgcacaaa ctggcggacg gggggcggca
     5701 tatcgacgag tcgctggcct tcagcctcct ccaggtggcc gacatgccgt tatcgccgcg
     5761 ggaattgagt gtgctctcga tggccgaagg gggtgacacc gtggccggga ttgccggtcg
     5821 gctgcacctg acgccgggga cggtccgcaa ttatctggcc gccgccatac ggaagtccgg
     5881 ggcgcgcaat cggctggacg cgatcagacg ggcgaaggag gcggggtgga tctgatgccg
     5941 cgccctttcc cccgcccgat accgacggcc ccgcccggct cctccggctc ccccgcttct
     6001 tcctgccccc ccgcttcgtc ctgctcgccc ggctcctccg gctccctcgt tccgtccggc
     6061 tccccggcgt cctccggctc ccagaggccg gccaggtccc ggtagagggc gcaggagctc
     6121 aggagttcgt cgggggtgcc gcactgggtg cgcgggccgt ccatcaccag gatccgcccg
     6181 gcgcggcggg ccgagctgag ccggtgcgcg acgacgacca gcgcgcccgg cagggccccg
     6241 aacgccagct cgacgcgggt ctcggcggcc gggtcgagcc ggctggtcgc ctcgtcgagg
     6301 atcagcagcg gcggggcggc gagataggcc cggcccaggg cgaccagctg ccgttcgccc
     6361 tgggagagcc ggtccggttc gacggccgcg tcgagggatc cgaggcggga gagcagcgct
     6421 tccaggccga gcgcgtccgc catggccgcg atctcccggt cgcgggcgtc ggggcggaga
     6481 tagcggaggt tgtcgcgcag cgagccgctg aacacgtagg cgtgctgggg cagcaggacg
     6541 cgtacggagg tggcgtcggc cgggcgcacc gggcgccccc gccaccgcac cgctcccccg
     6601 gtgggccgct cggtcccggc gagcacggcg gccagggtcg acttgccgct gccgctcggg
     6661 ccgacgaccg cgaggtgctc ccccgccccg accgtcaggg agagccggtc caggacgggg
     6721 tgggcgcccg gcccgtacgc gaagctgacc tcgtggagct cggcgaccgg ggttccgcgc
     6781 ggcggcgggg cggcgtcccg ggtgggcggc gggtcctcgg cgggcggggg cggcgcgtcg
     6841 gtgaaccggt ccaggaccac gacgagccgg cccccgacgg tgcccagcat ggtcatcagc
     6901 gcctggacgg cgggggcgag cgcctgggtg aggtaggtca gcgcgccgac gagcgcgccc
     6961 ggcgtgagcc cgttccgcag cagccagggc gctcccagga gcagcaggag cggggggaac
     7021 cggccgcaga cggcgagggc cagcacccgt acgcccgacc agcgggccag cgagcgggag
     7081 gcggctagct gcgcctcggc gagcgcccgg gactcggcca ccgtccgtcc ggcggctccc
     7141 gcggcggcga tgtcgcgtac ggaggcggtg agccggcccg cgtgggcggc gtacgcctcg
     7201 tcggcggcga ggtagtcgcg ctggcgggcg gccatcggcg gcagcgtgcc gaggaacagg
     7261 gcggacccca ggaccagtgg gggcagcacg atcaggagga gggcgggcga cagggccagc
     7321 aggccggtga cggccccggc caccgtgaac acgaacgagc gcagcgtcag gacgagtccg
     7381 gcccagccgt cccgggcgat ctcactctga tgagtgacct gtgacaggga ccgggtgctg
     7441 acgtcgccgg agcggtcgag cgcgccggac agcgcccggg acacggcgcg ccggaccagt
     7501 ccgtcgcgca gcggctccac gaggtccgcg agccggccga acactccgcg cgcggcgggc
     7561 acggagggca gcacggcgac cgcggcgacg gccagccaca ggagaccggt cgccggacgt
     7621 ccggcgagga agccgtcgtc gagcgcgcgg gcgaccccga acccgccgag gaaggtctgg
     7681 gcgaactcca gcagggacca gccggccagc cgcaggacca cgccggtccg ggcccgcagg
     7741 aagggccggg cctcgcggcc gacccggcgc agcgaggtgt cccgccggga gtgcgcctca
     7801 agctgggcgt cgcgccgggg gtgggccccg tgccgcgctt cgcgcccggg gagtgcgccg
     7861 cgccgggagt gcgccctgtc ctgcccgtcg cgcccggggt cagcctcatg tggctcctcg
     7921 cgcccggggt cagcctcatg tggctcctcg cgcccggggt gtgctccgtc ggccttcacc
     7981 gggcctccgc tccggcggcc ggtgtgacgg gcgtacggct cgcgggcacg gagtcctcgg
     8041 cgggtacgtc cgtgcggaag accgcccggt agtccgggtc cgaccagagt tcgtcgtggc
     8101 ggcccgtcgc gcggatccgg ccgtcctcca gccaggcgac ccggtccgcc cgcgcggccg
     8161 aggacagccg gtgggcgacg atgacccggg tgcagtgtcc ggcccgttcg tcgagggcgc
     8221 gccggacgtg gtgttcggtc acggtgtcga ggctggacag cgcgtcgtcg aggatcatca
     8281 gacggccggg gtgggcgaac gcgcgggcca ggccgaggcg ttggcgttcg ccgccggaga
     8341 gcggggcgtc ggcgaccgga gtcgcgtagc cgtacgggag cagcgcgagg aacccgtcgg
     8401 cgcgggctgc gcgggcggcg ccccgtacgg catcgggcga cgcggtccag ggcccgtagg
     8461 cgatcgtgtc ctcgacggtg gtgccgggga gggccgggcg ggcgaaggcg tacgccacct
     8521 cgcggcgcaa ccgggccggt tccatgccgt ccatcgggac gccgtccagc aacacgctgc
     8581 cggtgtccgg gtcgagcagt cgcccggcga ccgcggcgag caccgacttg ccggagccgg
     8641 agcgcccgac gacggccagg gaggtgccgc cggggaccgt caggtggacg ccggtcagca
     8701 gcgggccgcc gtcctgttcg acgccgacgt tccggagttc gaggtgcccg ggggcgtcgg
     8761 gcaccgggcc caggccgcgg tgcgggagcg gtgcgagggt caggaggggc tccaggctcc
     8821 gggcggcggc gcggctgcgg gcgagggcgc cgagcgcgcc ggtcagggcg ccgatgccga
     8881 cggcgaggct cgcgtagcgg gaggcggcga ccaggtcgcc gacgccgatc gcgcccgtgc
     8941 cgaggcgtag tccggcgacc gcgaggacca gcagcatgag caggggcagc aggaggccgc
     9001 tgcggccgac ggcccgcccg tacaccgtcc aggtgcgtcg gccgtgctgg gcgagggcgg
     9061 tcaggggttc caggacgcgg cggtgctcgc gggcgccggt gcgggcggcg cggatggtgt
     9121 cggcgccgtc gagggcctcg gtgagccggt gggcgatgag cgactgggca cgctggtagt
     9181 cggccccggc gtcggcggtc cggcgggtga aggcgcgcag cagtgcgacg aggaggggtg
     9241 cgccgaggag gagggctacg gccgtccaga cgtcgatgag gaggaggccc acgagcgcgc
     9301 cgagcgggag caggacaccg gagacggctc cggcggcggt gacgggcgcg gacgcggcgt
     9361 cggcggtgcg ggcggtgagc cgggcggtga ggtcgccggt gggcagggcg agggcgcggc
     9421 ggggttcggc ggccaggatc cgggcggcgg tgcgggtgcg cagggacgcg gtgagccggg
     9481 cggtggtggt cgtgccggtc acggcggccg ccgcgtcgaa cccggtctcg gcgagggtca
     9541 gggcggcgca gagcagcagc ccggaccagg gcacggggcc gccggcgacg agccggtcga
     9601 cggtgtggcc gagggcggcg ggcagggcga gggcggcgag tgccccgccg gtggagcaga
     9661 ggaggagccc gaggagggcc gccgggtact gccgggcgag ccgccgggtg ccggattccg
     9721 tgcccgggcg tgggtgcagc cgcacggggt ggcctttctg cccctggggg cacgtggccg
     9781 gccggcccac cggtgaggat caccggtggg ccggccggtg cgggtcacgg ggtgcagagg
     9841 accacgctga gggagctgta ctcacagacc agcagcgaga cctggctgcc cgtggcgagc
     9901 tcgccgaagg agtcctcggc cggggtgtcc atcgcctgaa ggtcgagaag cgccatgatg
     9961 tgtcctttcg gggacgttgg tggtgctgaa cggtgtgttg ctacgacccc tggcggggcc
    10021 ggtccgtggg gccgctcgcg cggccggggt gcgccgccgg agcggcgggc aggaagggaa
    10081 gtccggtgga gccgccgagc gcggcgccca gggcgaggag agcgccggcg gtcccggtgg
    10141 ccaggtccat cgacaggcgc atcaactgct cgcccgggaa ggcgagtccg tctccgtacg
    10201 ccagggcgtg actgcccagc aggtcggtgt ggcgggcgat ggcgcgccgc cggtcggcct
    10261 cgtcgcacag cggagtggcc gcgaggtgca tgaggagtcc ggccgagccc cggagcagtc
    10321 cgggctggac gtagaaggcg gagagcgcgg ccggcaggag ggcgcggccc gcagcttcga
    10381 gcgcggggtc cgggcggtgg gccagatagg cgtcgatgac ggccgcgatg ccggcgctgc
    10441 ccgaaccgag gtacggcatc agccgcttgc cctcgacgac gaggagttcg ccgtcgtccc
    10501 cggcccggca gcgttccagg tcgcggcgca gggcggtggc cgccaggtcg agcagggcgg
    10561 cgtcgccggt ggtcgcgtac cggcgcacca gcagcagggc gatgccgctc gcaccgtgca
    10621 gcagtccggt gcggggcgac ggcgggccgt cgacgagcgc gcggacggcg agggcggtac
    10681 agcgggcggc cgctgcggac agcgccgggg cgtcggtggc ggaggcggtg cgggccaggt
    10741 cgtcgagggc gaggccgatg cccgcgtacc cgttgtggag gccgggcgcg agcccctgca
    10801 ggggctggtc gaggatgatc cggaggaggt cggcggcctc ggcggtgcgg ccgatccggt
    10861 gcagggtcca ggcgatgccg gtgagcccgt cgtagaagcc gagggggctg ccggacgccg
    10921 ggtccttggc gtgccgcagg agccactcct cggcctcatc gcacggcggg gcgcccgtct
    10981 cgtggagggc gtagagcact ccggccgccc cgtacgcgaa ggactggccg ccggtggccg
    11041 tggcgaactg ggcgatgtcc ccggggaagc agcggtcctc gcgctccggt gtgcaggagg
    11101 cggtgatggc ccggaccagg gcgtcacggc tgcgcggcca gtcgccgggg tcgggcacag
    11161 gagcgggagc gggaacggaa gcgggagggg gagcttgaag ggaggcggga gcggcccggc
    11221 ggacgggctc ccccgtgtcg cgcaggatct ccgcgaccgc gggccgcagc gtctcctcgg
    11281 tgaccgggaa gacgcgggcg atgtcccggg cgaggccggc ggccttggtg cggtcgatgc
    11341 cgaacagcgt ggtgagcggc aggtacaggg cgagccgcag gcaggcgagc gcgtagcggt
    11401 cgatgtcggc gccgcgccgg tcgggcgggg cgacgaaggc cgggttggcg acgatctggc
    11461 ggcggcgttc ggcggccggg gaggccgcct cgaagtcgag caggacgatg cgcgcgttct
    11521 cctcgtcgac catcacgttg ctcatgtgca ggtcgctgat gacgatgccc cggtcgtgca
    11581 ccgcctcgac ggcgcgctcg acctgcccgt acaactccgc agcccaggcc gcgtgttcgg
    11641 cgagcagttc gggtgacggg tgctgccggg cgagcgggaa gcggcgggcg aagacggtgt
    11701 tgagggtggt gccggggatg tactggagga ccaggaagtg gtggtcgccg acctcgaaca
    11761 cgtcccggac ggccggtacg cagtccagtc cggccagttg ctccagggcg gcccgttcgc
    11821 gctccagccg ggccacggcg tccgcgccgt cggcggccag accggcgtac ggtcgcgcct
    11881 ccttgaggac gacctgctcg ccggtgcggg tgtcgcggcc gaggtagacc ccgccgccgt
    11941 tggagaagtg cagcgccttc tccacggtgt acgggaggtc ggccaggccc acggcggcac
    12001 gggcttcgag gtgcggcatc aggaagccgg gcggggtcac ccaggagggg acgcggaagg
    12061 acgggccccg gtcgtccggg acgagccggc cctgcggatc ggcgacggcg ggcacgggcc
    12121 gcccgtccgg gccggagcag aagcgggcgg cgaacgcccc gtaccgggtg tgcacgggcc
    12181 cgttcccgca ccgcaggtcg ctcagaatgt acgggccgtg ctcgccctcc agcaggtggg
    12241 tcagggcggt gcacacctcg gggaacgcct cgtcggacgg cgggtagacg gtgatgaact
    12301 tcccgctgcc cgcccggtcc gcgtacttgg cgttgcgcag ggccaacagc ccggcgttcg
    12361 gtacgcactt gaaggccagc cggtgttcca ggcagtgggc gacgacccgt tccagcacgg
    12421 aggccgcgtt gtcgagggcg gccgagacgt ggatcttcca gccctggggc ggcagtcgca
    12481 gcccgtcggg gctgtaagcg agccagtcgc cgcgccggga gcgggtccag ccgtcgggta
    12541 cggcgccacg gagcggcgcg tagaacgagc gctcctcgtc ggcggctccg cccggtccgg
    12601 gggaacggtg gggtgcgtcg tagaagcggc ggtccgcctg gcagtacgcg gcgtactccg
    12661 gattcacgca cggtcccctc gctcggttct ttcgtggcga gagagaaatt gtcacaacga
    12721 cgtgtggcgc ccatagtcac tgttgtcacg actcgtacat gcgcgccaac catgcggagc
    12781 gcaccgcgta ctgatgggta tccgcttgcc gcccagccct ggacgggtgc ggactggggg
    12841 cgtgcggggg cgcgcgcggg gcgctctcac gcccgcctca gcccgcgccg tgcaccagaa
    12901 cgtcccccgc ctccgtacgg aaatagagca cggagcggcc cgcgcgccgg cggcggacca
    12961 ggccggcctc caggaggatc cgcagatggc ggcccaccga gcccagcccc tggccggtca
    13021 gcgcgacgag ctgcgtcgtg ctcagcgggg aggcgagcag cagcaggacg gccgcccgtg
    13081 ccgggccgat cagcgccccc agggcggcgg gcacggggat gcgcccggcc tcggcgagcg
    13141 cgccggagca cgggtacacc agcccgtacc ggcgcgggat gtcccagcag acccaggact
    13201 ggtacggggt cacggggacg aacagcaggt gggcgccgtc cagttcgcgg ggcgggttgt
    13261 cgtgggtgtt gatctggagc cggctgtcgc ccagccaacg gatgccgggg cgcatgccgt
    13321 tcagcgcgtc gacccagcca ccgcgcccca actgggcgga ccgggcgacg acatcggcct
    13381 ccaggatccg ccgccgcctc ggccagtcgg gcagcacggt gtgggtccag acccactcca
    13441 gggcgtcggc ggcacgccgg gccaggtcgt cccggtccag cgcggcgggc aacggcccgc
    13501 gcaccgcctc ggccaggtcg gcgcgggccc ggtcgggcgg ggtggcccgg acgggcgtca
    13561 gctcgtcggc gaaggagggc ggggcctggc cgggcggggc ggggtccggc acggggatga
    13621 ggaagtcggc gatccaccgg ggcgcgaggg cggcgccgac caccagcgcg gagaccgggt
    13681 cgtcggcctt ccaccgccgg tacgcgggca ggtgggtctc cagccaggcg cgctcacccg
    13741 ggtgcgcggc gccggcccgc tccaggacca gcaggctcgc gacggcctcc gcgagcggcg
    13801 agacgacgaa ccggctgttc gcgagcgtgt ccgcaccgac ctgccaccag cccacgcgcc
    13861 ccacccctcc cgttctccga ccgtgcctgt ctctgcctgt cctgcctgcc tgccccgggg
    13921 ctttcgcgtc cgcgcgaaac agtaacggtc ccggcgacgg cgtccggaga ctccacccca
    13981 tgcgcaccta ccgcgaactg ttccggaccc cggagttcac ccccttcttc gccgccgtct
    14041 ccgcgcagac ggccgcccag accgcgaccg gcctggcact gggcaccctc gtgtacacgc
    14101 ggacgggctc gcccctgctg tcggcgctgg cgatgttcgg cccgtcactg gcccaggtgg
    14161 ccggggcgct caccctgctg tcggcggcgg accggctgcc gccgcgcgcc gcgctgaccg
    14221 ccctggcgct gctctccgcc ggggccgcct gcgtccaggc cgctcccgga ctgccgctgt
    14281 gggccgcgtt cgccgtcctg ctggtggtgg gcgcggcctc gtcaccgggc gggggcgtac
    14341 ggtacgggct gctcaacgag atcgttccgc gcgagggatt cctgatcggt cgctccgtgc
    14401 tgaacatgac gggcggcgcc atgcagatct gcgggttcgc ggtgggcggg ctgctggtga
    14461 cggtgttctc ggcgcgcggc acgctgctga tcggggcggg gctgtacgtc gtcgcggcgg
    14521 ccgtgacccg gttcgggctg accccccggc cgccccgggc caccggccgc ccgtcggtcc
    14581 gcgagacccg gcggacgaac gcgctgctct ggtcgtccac gccgcgccgg tacgtgttcc
    14641 tggcgctgtg ggtgcccaac gggctcgtcg tcggggccga gtccctgtac gtcgcgtacg
    14701 cgcccgggca cgccgggctc ctcttcgccg gcggggccct gggcatgctg gccggggaca
    14761 tgctggtcgg gcggttcgtc acggcacggt ggcggacccg gctgggggcc ccgctccggc
    14821 tgctgctcgc cgcgccctat ctgctcttcg cactgcgccc ggggctgccc ctcgcgctgg
    14881 cggcggtcgt cctggcgagc gtgggcttcg ccgcgagtct gctgctccag gaacggctga
    14941 tggccctcac cccgcaggag ctgagcggcc aggcgctcgg gctcagctcc tcggggatgc
    15001 tcgcgatgca gggggtgggg gcggccgtgg cgggcggcat cgcccagctg acctccccgg
    15061 ccacgggcat ggcggcggtc gcggggctct cggtggcggt gacactggcg ctggccccgg
    15121 gactgcgtga ccggtccggg ggcgtcgggg gcagactgcc ggtagcggac ggatcaccac
    15181 gagcgtcccg tacaccccgc acggaagaga ccacatgagc gacaacgcca ggcccagcca
    15241 gaaggaagcc atgctctccg gcgagctcta catcgccgac gaccccgaac tggcggccga
    15301 ggcgcagcac gcggccgtgc tcagcgagcg tttcaacgcc acttcggccg ccgaccccga
    15361 ggcccggcgc gccgccctgg ccgaactcct cggcgagctg ggcgagggcg tggaggtgcg
    15421 gccgccgctg cgggtcgact acggctaccg gacgaccatc ggcccccgga cgttcatcaa
    15481 cttcggcgcg gtcctcctgg acgtcgcccg catcaccatc ggcgcggacg tccagatggg
    15541 cccgaacgtc cagctgctca ccccgaccca cccgatcgac cccgagccgc gccgcgccaa
    15601 gtgggaggcc gcgcagccga tcaccatcgg cgacaacgtc tggctgggcg gcggggtgat
    15661 catctgcccc ggggtgacca tcggcgagaa cacggtggtc ggggcggggg cggtcgtcac
    15721 gaaggacctg ccggcgaacg tggtggcggt cggcaatccg gcccgggtga tccggaagat
    15781 cggcgagacg gaggcgtgac accccggggt ccgcggccca ccggcgcggc accccggttt
    15841 cccgctgccc gccgggcata gcgccccgcg cgctacgcgg cacgccaggc gtcggtgacg
    15901 cacgagacct cgaagtgcca ccagccctcg tcccggccgc gggcgagcag cgccttgacc
    15961 ccgcgcaggt ccgcgccgcc cggcacggtc agggcgacca gcgggaactc cgcgctgaag
    16021 acctcgcccg tgagcccgaa gacggcgagc cgctcgtgca cggcccgggc gtcgcgcccg
    16081 agcggtccgt ccggcaacgg cagcacccgt acggtgcagt tgcccgactc ggccacgcgg
    16141 ccgacggccc agtggacccc ttcgtcgtcc gtgcggaacc gtacggtctc gccctcggcg
    16201 accccgtcct ggaagaaggg cacgttgtcc acccgcgcgg tgtccgggcc gagccgcgtc
    16261 gcccacaacc cctcggtgtc atagggcagc cagccctcgc gcgggacgaa gcggaaccag
    16321 accttgatct gatcggcttc gcggggcggg cgttccggac cggcggggga actcatggcc
    16381 ccatggtccc ccgcgcccgg cgcgcccgcc tgtccacccc cacgaccagg cacgacgtca
    16441 gcttctgaag ccagaggccg cccccaccac gccgcaacct ccaattcccc aacacttgac
    16501 gccagttgtt ggattcagtg gcatctcctg aggctcctga tgcacacctc ttgacgcgta
    16561 caggcccacg ggggaaacat caccgttacg agagagcgct ctcccgcagc ctccccccaa
    16621 agctctcccg tccgctcgtc gtgcacacgt accacgaccc aggagacgta cctcatgcat
    16681 gctcccccca ccgcaccacg cacccgcctc cgcacccggg ccctcggatt cgccgcgctc
    16741 gccgtggcga tgctcatgtc cgtacccacc gcacagaccg ccttcggcga ggaggtccag
    16801 gcggtgccgg gcggcggcga cctcggtccc aacgtccatg tcttcgaccc gtccacgccc
    16861 gacatccagg gcaaggtcga cgagatcttc aagaagcagg agtccgcgca gttcggcacc
    16921 gaccgctacg cgctgatgtt caagccgggc acgtacgacg acatcaacgc gcagatcggc
    16981 ttctacacgc agatcgcggg tctcgggctg aacccgaacg acaccacgtt caacggtgat
    17041 gtgaccgtgg acgcgggctg gttcgacggc aacgccacgc agaacttctg gcgttcggcg
    17101 gagaacctga ccctcaaccc ggtctccggc accaaccgct gggcggtctc ccaggcggcc
    17161 ccgttccgcc ggatgcacgt caagggcggc ctcaacctgg cccccgacgg ctacggctgg
    17221 gccagcggcg gctacatcgc cgacagcaag atcgacggcc aggtcggccc gtactcccag
    17281 cagcagtggt acacccgcga cagctccgtg ggcggctggg gcaacggcgt ctggaacatg
    17341 acgttctcgg gtgtcgaggg cgccccggcc aacagcttcc cggagccgcc gtacaccacc
    17401 ctggacacca cgcccatctc gcgcgagaag ccgttcctct acctcgacgg cgacgactac
    17461 aaggtcttcg tcccggagaa gcgcgagaac gcgcgcggca tctcctgggg caacgggacg
    17521 ccggcgggcg agtcgattcc gctggaccag ttctacgtcg tgaaggaggg ggcggacgcc
    17581 gccaccatca acgcggcggt ggagcagggc ctgcacctgc tgttcacgcc cggcgtctac
    17641 cacatcgacg agacgatcaa catcgaccgc gcggacaccg tggccctcgg cctcggcctg
    17701 gccacgatca tcccggacaa cggggtgacc gcgatcaagg tcggtgacgt gtccggtgtg
    17761 aagctcgcgg gcctcctggt cgacgcgggt ccggtgaact cggagacgct gatcgaggtc
    17821 ggccccgaga acgcctcggc ggaccactcg gcgaacccga cctcgctgca ggacgtgttc
    17881 gtgcggatcg gcggcgcggg tcccggcaag gcgaccacca gcatcgtcgt caacagcgac
    17941 gacacgatca tcgaccacac ctgggtgtgg cgtgccgacc acggtgaggg ctggggctgg
    18001 gagaccaacc gggccgacta cggcgtccgc gtcaacggcg acgacgtcct ggccaccggc
    18061 ctgttcgtcg agcacttcaa caagtacgac gtggagtggt acggcgaacg cggccgcacg
    18121 atcttcttcc agaacgagaa ggcctacgac gccccgaacc aggccgccat ccagaacggc
    18181 gacaccaagg gctacgccgc ctaccgcgtc gacgactcgg tcgaacagca cgagggctgg
    18241 ggcatgggca gctactgcta ctacaacgtc gacccgacga tcatccagga acacggcttc
    18301 aaggcgccgg tgaagcccgg cgtgaagttc cacagcctga tcgtcgtctc gctcggcggc
    18361 aacggccagt acgagcacgt catcaacgac gtcggatccc ccacgtccgg cccggacacg
    18421 atcccctccc aggtcgtgaa cttcccttag tccccgacgc gggagtctta cgggagcggg
    18481 gcccggctgc tgttgagcgc cgggccccgc tccgctgtcc acggcctagg tgtgcagcgc
    18541 caccgctccg cgcgccggga ccgtgatcgt cgccgtgccg tcgtccgcga ccgtggtccc
    18601 gttgccgtcg caggagtcgg gggccgcggc gaccacattg cagtacgtgc ccgccggcag
    18661 cgtcgtcgtg aaggtgcggt tcagctccgc gtcgccgttg ttgacggcga cgaagccctt
    18721 gcccgcgcgg gcgaaggcga gggcggagga gccgtcgtcc caccagtcgg tcagctccgc
    18781 gcccgcgacg gcgttgtgga agccgaccat gccggtgacc gcctgctggg cgtgcgtgca
    18841 ggtccacgcg ccggagccgc agtcggcagc gccgccgttc ggcgggccgg cgtccttgtc
    18901 ggtccaggtg tagccggaga agacgttcgg ggagccgtag ggcgaggcca gcatgaagac
    18961 gttggccagg gtgtaggcgg cgccgtcctt gtgggtgagg gtggagccgt tgcgctcggt
    19021 gtcccagttg tcgacgaacg tacgggcgga ggcgccggcc agtttgccgt cggcgatcga
    19081 cttcaggccg ggcaggccgc cgccctggaa ggcggacttg aggtggccgc cgtaacggaa
    19141 ctcgtcgacg tcaccgatcg aggtgtactc ctccggctgg accgcctctc ccccgccgtg
    19201 gatgacctcg gtgacccaga accccgggtc gcccgtcttc cccttgatcg cggcgacgtc
    19261 atcggcggac atgtgcttgg cggcgtcgat gcggaagccg tcgacgccca gggagcggag
    19321 gtcggagagg tgggcggcga tcgtcgtgcg tacggcgtcg ctgccggtgt ccaggtccgc
    19381 gaggccgacc agttcgcagt tctggacgtc tccgcggtcg ccgtagtccg cgatgtcctt
    19441 gcggcaggtg tggaagtcct ggtcctggaa cgtgccgggg tagtcgtact tggtgtacga
    19501 cgtgccgccc gtcccggtgc cggagccggc ggccatgtgg ttgatcacgg cgtccgccac
    19561 gaccttgacc ccggccgcgt ggcagctctc caccatcgcg gcgaaggagt cccggtcacc
    19621 gagacggccc gcgatcttgt agctgaccgg ctggtacgag gtccaccact ggtcaccctg
    19681 gatgtgctcg gtggcgggcg agacctcgac gtagccgtag cctgccgggc ccagggtgtc
    19741 ggtgcaggcg gtggccaccg cgtcgtactt ccactcgaag agggtggcgg tgacggtctt
    19801 ctcgcccggt ggggtcgcct gggagggcca gggcgcgagg accgtgaggc caccggcggc
    19861 gagcaggccc gccagggttg cgcgtgcggc gcgggaactc aattgcggct ccttcggtcg
    19921 cgggtacggg cgttcgcccg tgcccggcgt gggcagccac gcgcctggct gccgtggggg
    19981 gagttcggag cctgccgttc ggggatggac acgtcaagac gtccgcaagg gtttccaggt
    20041 tgtttctgaa agttcttacg agatgggcaa gttggggaga agtcccgccc ggaacgagcc
    20101 cggaaccagc gcgaaaccgg tgcggaaccg gcccggaacc cgcccgccga cggctccgcc
    20161 cccggccgga tacattcccg ggcgggggcg gagaggtgga gctggtgtcc ggtccgggcg
    20221 tcagccctgg ccggtcaggt cgatggtgac cgtgcgctcg gcgggggtct tcccggccag
    20281 ggcggtcttc atcgcctggg ccacgtcgtc cgcgccgacc tggtgctcct tgccgtcgcc
    20341 cttgaccgcc atgatgccgt cgaagacgcc gtccaggagc ttgtcgatcg cctgcttgtc
    20401 gtagacgtcg accagtcggc cgtccacggg cttcatggag aggatctgcg gcagcgaccg
    20461 ggccgggccg aactggatct ccttgggacc ggccttgatg gtgatcaggc cggacatcgc
    20521 gggctcggcg aactccttca tcgcccggtc cagttcggtc tgggtgatgg tgggctcgct
    20581 ggtggtgacg gggagttcga ccagccgggc ctgcccggtc tgcacctggg cgcggtaggc
    20641 gtcccggacc gagatcaggg actggccggc gtccagcgtc ttgcccggct tgcccggcac
    20701 cgccacggcc ttgttcggct cgaagcggat cgtgccgtcg ttggacgagc cggagacgcc
    20761 cgccagatcg gtcagcgcca caccgagctt ctcctcgtcg accgggatca ccgggtcggc
    20821 gggacgttcc ccgccgaaca gcgaaccgat caccgagacg gggttgtagt cgctgcccgc
    20881 cgcgccgcgc acggtctcct ggctgtccag ggtgagaccg gccttctcgg ggtcgagctt
    20941 ctcctccttg ccgtccaccg acagctggag gggcgtcttg gcccgctccc cgagggcggc
    21001 ttcgagcttg gtgaccgcct cctccttcgt gccgccgccg atgtcgacgc cgagcaccgt
    21061 ggtgcccttg gggacctcgg agtggttcag caggagaccc gccccgtacg cgatgccgag
    21121 cagcacgacc gcggccaccc cgaggaggac cagcttggag cggcccttct tcgcgggtgc
    21181 gggggcggct gcctgggacg cgggacgcgg ggcggcgggg ccgggcgtgg gaacgccggg
    21241 tccacccggg ccgccggggc cgccctgggg tccgccggcc accgggccgc cggggatacc
    21301 ggggccgccc gggaacgcgg cgcggggctc gctgggcacc acggggatgc cgctggtcag
    21361 cgtgtcgccc gagacatggc cggggccggg ctcggacgcc ggggcctgcg gcgtgaggat
    21421 cgcggtgtcg tcggacatcc ggggcggtac gccgccgggg acgcccggga ccatcggtcc
    21481 ggggccgccg agacccggga cgccgtcgag gcccgggaca ccgtcgaggt tcggggtcag
    21541 cgaggagctg ccggtgaccg gtcccgtggt ggggccggac gggccgggcg ggccgggcgg
    21601 gcgcaccccg aggccggggg tggaacgggg gcctccgccg gggggctcgg tgccgtagcc
    21661 gtcgagcgcg ctgcggccgg ggccggggcc gggcgtgccc ggtccgccgc cggactgcgg
    21721 ggcgtccgag aagtacggca ggtcaggacg cgaggggccc gcatcgccgt cggacccgcc
    21781 accggggccg cccgcgctcg ggccgccggg tccgcccgtg ccggggccct gggcgccacc
    21841 ggggccggaa ggagcgccgc cgggggcgcc gggcgcaccg gtgccctggg cggctgctcc
    21901 cggcccggtg gccgaggtct tgcgcggggc gaaccagtcg ctgccgctct tctcccggcc
    21961 cggcttctcc gcgggcgccg ggtcggcggc cgggccgccg tcccggggcc ggtccgcggg
    22021 cgccgcgccg ttcgggcccg cggagcggtc cgaaggtccg gctccgggtg cgggcggcgg
    22081 tgtgccgggg cgcggggtgg cgccggtccg ctccgcgtcg gaacggccgc cggcgatgtc
    22141 gctctccgcc atcggcgtac gcatcacgac cggcgggatg ggacgcgacc cggggatgtt
    22201 gatccggatg cgcgtcgtca gcgtcgtctc ggtcttcggt tcctcgggcc ggggcggagc
    22261 cacggattcc gggttctcgt cagagccgtc ctgcgacggg tggagcgacg gatactggcg
    22321 ggatccgtac ggcggcgtac ccgaggggta cgcggctccg ccgcggccct gggggccgga
    22381 ggacgaactg tcagtttcac gactcaaagc aggttctccc gattggctcc gccgcccgta
    22441 cttcccccat gccgcaggcc aggggacggc tcggcgcgcg caccaccata ctggccgcgg
    22501 ccgtcggaca ctccgcgacc gggtgaaacc tccacccgcg catcacacct gtgggggtct
    22561 ctgcggaccc gtacttggca cttcacgtac cggaccggcc gctgcggatg gctgattgcg
    22621 gcactttgga cgtggtggcg cacatcacag cggcggccgt ccctccg
//
