LOCUS       NZ_LFBV01000012        26305 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces uncialis strain DCA2648 scaffold12, whole genome
            shotgun sequence.
ACCESSION   NZ_LFBV01000012
VERSION     NZ_LFBV01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces uncialis
  ORGANISM  Streptomyces uncialis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 239521)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Cloning and characterization of the uncialamcin biosynthetic gene
            cluster
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 239521)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33410, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-MAY-2015
            Assembly Method                   :: CLC Genomics Workbench v. 8.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905345.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:03:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,456
            CDSs (total)                      :: 7,371
            Genes (coding)                    :: 7,214
            CDSs (with protein)               :: 7,214
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 5 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 42 of 157
            Pseudo Genes (incomplete)         :: 143 of 157
            Pseudo Genes (internal stop)      :: 7 of 157
            Pseudo Genes (multiple problems)  :: 33 of 157
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:56:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 110674
            Orig. end                         :: 136979
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LFBV01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26305
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26305
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26305
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16305](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16305
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    74..83
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     gene            complement(1367..2047)
                     /locus_tag="AB852_RS35690"
                     /old_locus_tag="AB852_35125"
     CDS             complement(1367..2047)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS35690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_35125"
                     /product="hypothetical protein"
                     /protein_id="WP_073795358.1"
                     /transl_table=11
                     /translation="MTAVDQLIGEIKSFLAAGTISYDAASKPSDVYEGFIFSLIVATAS
                     RHGATVRYEDVYGAKVNNLVFRTGPGHLYGDSQPFTHAVIEFDGAPALEVHLGVFVTGS
                     SGVLHECDVLVLPAEEAALSREQGVEPRGSQSILIVECKYYVSNLGIGLARNFEGLRAD
                     IRTQSELFVSNIGSPSIVRYLDARKRGFERDVVPNSPQAGYLQAEIRKTFKSYLNKHSP
                     STVI"
     gene            complement(2044..2604)
                     /locus_tag="AB852_RS35695"
                     /old_locus_tag="AB852_35130"
     CDS             complement(2044..2604)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS35695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_35130"
                     /product="hypothetical protein"
                     /protein_id="WP_143201325.1"
                     /transl_table=11
                     /translation="MNPFELRRTEQALREALQGTALAWVLDDVDAAIAAGVPEEKILRR
                     RPQRRGDESHAATPASAALRYEVVDRNLLGASEYEASRKRGTLVIATRAMTDQERVQLL
                     LDAVRRVLVELPEIERETLKTLQAEPGGDDGRRTMVEGVVFEPDERTRSRRSRTEILVN
                     RVPTERRERVSQLVTEVSREVRR"
     gene            complement(2830..5253)
                     /locus_tag="AB852_RS35700"
                     /old_locus_tag="AB852_35135"
     CDS             complement(2830..5253)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016724.4"
                     /locus_tag="AB852_RS35700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35135"
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="WP_073795363.1"
                     /transl_table=11
                     /translation="MTWIDYDASLVDDIAARLDLRAPNAAAVRAVAEAIADGNGREVVC
                     DLATGVGKTYILAGLVDYLAAQGVRNILVVTPGTTIQDKTVANFTPGHAKFVNGSDAEP
                     LVITSENFSRGQVGDALHDDTITKLFVFNVQQLIRPSDKTSRKVRARDEFIGTGLYQHL
                     QQVEDLVVIADEHHVYSSRAKSFNQAIEELGARAVVGLTATPAPGVKPIFQYSLAEAIA
                     DGFVKIPVIVYRPDGRKDESTVLADACHLLRIKDAAWTAWAEAQGRTPVHPVLFVVCRD
                     IPDAERVANRLTADDMFPGEGQVLTITSQSSDTALRALAAVEEADSPVRVVVSVNKLKE
                     GWDVKNIGVIVGLRALASETLTEQVLGRGLRLPYGRRVGTPMVDTVDLVAHESYRQLLA
                     NKDALLQQVLPADGGDLDKGRPQPAPVANQPSSGDEQQILTFTSRPRVIGDDLVDGSPL
                     LHVESFDAVMAQGKRDAKAVTTLRTKVPGAPTIRFPRREREILPVRFSFSYIDNAAVRS
                     EGAAYKHEFKVPLVRQAVDAQRGLDSKVGTFVTAAESVDATQKFISISELRNDLFGRIW
                     NIGYVEETLAESRAAERVVREFLAGAGVTAEDQEHEWSELRAAQAATSLGELVKTAYDT
                     RKLQPTYAFRPVDVPTVPPPPMPSNVVSKWADFRKDLWYEGWEHSVEPVASFDAGSTEY
                     ALAHLFDASPSVQWWLRNYDPGPIWIERDNGKKYYPDFIVLDNEGTYWVVEGKANDRAN
                     DPEVLEKRRAAEDWARFVRDYGEFGTWRYIFATEKIIKGAKGSWESLIALAKPE"
     gene            complement(5250..6842)
                     /locus_tag="AB852_RS35705"
                     /old_locus_tag="AB852_35140"
     CDS             complement(5250..6842)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013704.4"
                     /locus_tag="AB852_RS35705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35140"
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="WP_073795366.1"
                     /transl_table=11
                     /translation="MTSGRLTLSWVGRDEALRNTADGGYEWVSRQDPRVTEVRLLQETG
                     KAGDVTGTAADNLLIHGDSYDALLALVRNPEYGDHYRGKVKLVYIDPPFNTGQAFQHYD
                     DALEHSVWLTMMRDRLLLIRDLLAPGGSVWVHLDDAEMAYCRVLMDEVFGRGNFVGTVV
                     WQKIHARNNSAQHLSSVHDYLLVYARSKSDLVLNKIDRTELSDQEFWNPDNDPRGPWRR
                     SDLTASHAYEDGRYEVVGPHGDVFSPRGNRWWSCSRETFDSLREDNRLWWGKTGRTFPF
                     RKRFQSELGGLVPTTFWTHDEVGDNRQAKAEVTKLFDRSRIFSTPKPEALLKRVIQIAT
                     DPGDVVVDVFAGSGTTAAVAHKMGRRWVTAEILEETAETFTRPRLEKVVAGDDPGGITK
                     TVGWEGGGGFRSLKASPSAFEIADGRVFLADWVKGEDFTAVVAAQLGFMYDSADGGPFC
                     GTKGRARLAVVDGVVDEVVARGVIGHLDEGERAVIVGRGITPEAESLVAELSRGSKVLK
                     APRDLVRRGKAVR"
     gene            complement(7088..7630)
                     /locus_tag="AB852_RS35710"
                     /old_locus_tag="AB852_35145"
     CDS             complement(7088..7630)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000005.1"
                     /locus_tag="AB852_RS35710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35145"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073795369.1"
                     /transl_table=11
                     /translation="MTTAPTIELRTFTTLDPVRGDLLDVYADVRAPLLHLPNYAVTTFG
                     ERLDRHGTEPGFVAVLAYADDEPVGYAYGNTIERGDRYWQRTTPEPAEKYTERPALALK
                     EIGVRPAWRKTGTARRIHDALLATTCDEMHVTLMVNPAAGDGKVHALYRSWGYKNIARS
                     QPSPASPLLIVMVRAIR"
     gene            complement(7627..8910)
                     /locus_tag="AB852_RS35715"
                     /old_locus_tag="AB852_35150"
     CDS             complement(7627..8910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383502.1"
                     /locus_tag="AB852_RS35715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35150"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_245877049.1"
                     /transl_table=11
                     /translation="MDATRNTVLEAWMEEHGYSSNSLADAVNRSLEQLTGRSGGLDGSS
                     VRGWKAGRVKWPKTATRKALEEIAGLPATALGFVPRGRTPSALVPPQQEDPDMKRRTLV
                     GGITAAAVAAASPGTASPRRIGMSDVDRLQKRFAEIIASDHRHGGQLGIEQRAASLADE
                     ALNLQNSGSATQRVRSSLYASAAAFRSSAMWAAIDGRRYDDAKTHMREAQTLAEMSGDQ
                     AIKFRIWSHTGTMYRHLGRPADALAANDVARNLFLTRRDPLFASLGLARQGAIQGTAQD
                     RSGMRRTFDQAQEAMLRSDPTEYRPVWMLAFYDQAELDSLALSANLALGDYPTAEYHAH
                     RCLSALRPHMIRSRAIATTRLAHAQLAQGAADAATATAMKVPTDVATHHARVARMLQEF
                     GAALRATAPGSTTAQTWTEHAATWRTTA"
     misc_feature    complement(8683..8685)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8818..8820)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9142..>9582
                     /locus_tag="AB852_RS35720"
                     /old_locus_tag="AB852_35155"
                     /pseudo=""
     CDS             9142..>9582
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000003.1"
                     /locus_tag="AB852_RS35720"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35155"
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSLNTPVHAARVGRPAYSQTIPCQPSTAETCRKLVHRVLGAWCL
                     DELADGAVLIVTELIANASKHTSCHDIRLTVGRPSASRVRVGVVDWEPERLPAAGHANH
                     GDESGRGLLLIDAVSDCWGYDLYGSDRCPWGKEVWAELQLTGD"
     gene            9643..9822
                     /locus_tag="AB852_RS38205"
     CDS             9643..9822
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="AB852_RS38205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_079185188.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.5e-14, bitscore:
                     46.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRNTVIPSLTQVRPQAAEASDGFDLDVSLVEIADPAGLVNLTDD
                     NCGTTCGACTTNVA"
     misc_feature    complement(9851..9860)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            10001..12973
                     /locus_tag="AB852_RS35730"
                     /old_locus_tag="AB852_35160"
     CDS             10001..12973
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612044.1"
                     /locus_tag="AB852_RS35730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35160"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_178391210.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.7e-199,
                     bitscore: 656.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.1e-16,
                     bitscore: 54.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.4e-24, bitscore:
                     80.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDGLPGAAADQAAWLRAVWADEDFAETLQHSSPALATQVQSLCT
                     GQRPDPRDLRRAVLSVIRYLLRAQHRATPFGLFAGVTTATFRPRASASWGEEHVLVGKA
                     GAEWLATVVQRLESCPELLERLPVVANSTASVRGDRLIVPFQSDDRGDEIRAVEASLDL
                     TAPVLAALTAAEAPIRVGVLLSRLRVEFPEAGPEKPRRLLAELIRRRVLITSLRAPSTE
                     TDALGYLVDQLDAVEAESVAPISKTVAELRAIRAALGGCSTRGGRYRAAARMREFVPDG
                     NRHPVAFDLRLNAKLVLPEVVAQEIERAALVLTRLSARPYGTAAWGEYHQRFYERYGIG
                     TMVPLKEVVADSGVGYPDGYPSMPGGARRPRVSARDDVLVRLAQTAALEGQEEVVLTDE
                     LIAALDVGPDEPRVPPHLEVGVRVHSASLKELQRGRFRLEIVSVSRGAGVSTGRFLGVL
                     EPADREALSKELADLPTADGDTVPAQLSFPPLLPESTHVTRAPQVLPTVISLQEHRAPD
                     PDVLTLDDLAVACDGRRMYLAAPGRGHRVEAVGMNALNLRTHTPPLARFLTELSRAQCA
                     QVTVLDWGVAAAMPFLPRLRYERTVLAPARWRLESSELPSGAEWDAALASWRVRRRLPR
                     QVYLVEGDQHLFLDLDEASHRTLLRQHLDQPRTAVLVEAPERYGWCDGRAHEVVLPLKA
                     VRPTAWPPLPAPTSARALSPAQMQTPATSSVLLATLYGDARRQDTVLAQHLPGLLERLG
                     NPPWWFIRFRDQAQHLRLRIALPHPGAFGETARTVSEWADELRRAGLLADLRYPTSYRE
                     MGRWGSGAAWKAAEDVFRADSRAVVTQLAQRQRPTQRPLVAAHTISIASAFLGSTEAGM
                     RWLVDHIPPTAPTPVPRPQFMEAVRLADPRGDWAALRRVPGGEAIVSGWAERDAALAAY
                     RPHLPGPDTQGIAVDDVLTSLLHVHFVRHVAVNFPEEEVCLYLARAAALAWTARTKGRP
                     S"
     misc_feature    10193..10195
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10382..10657
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AB852_RS35730_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.80E-17"
                     /identifier="RREFam001.1"
                     /label="AB852_RS35730"
                     /locus_tag="AB852_RS35730"
                     /protein_end="219"
                     /protein_start="127"
                     /score="54.2"
                     /tool="antismash"
                     /translation="VVANSTASVRGDRLIVPFQSDDRGDEIRAVEASLDLTAPVLAALT
                     AAEAPIRVGVLLSRLRVEFPEAGPEKPRRLLAELIRRRVLITSLRAP"
     gene            12970..14202
                     /locus_tag="AB852_RS35735"
                     /old_locus_tag="AB852_35165"
     CDS             12970..14202
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543780.1"
                     /locus_tag="AB852_RS35735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35165"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_073795374.1"
                     /sec_met_domain="LANC_like (E-value: 5.5e-48, bitscore:
                     157.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHPAFDLADAIAAQLADPDVPRSWAVPAYGQHLAYGPPGIALL
                     HIERAARGLGPWQRAHDWLAAASRHPLTSGPDSHPFYGAPALAHALACAADSLPGAYQS
                     ALDSLDRRIVVDVRRRLDAAHRRIDAGRLPQLAEFDVIRGLTGYGAHLLHRSPDGNTVR
                     AVLDYCVRLTEPLTDQDETLPGWWTETGPSGNPDDRFPGGHANHGMAHGIGGSLALLAL
                     AARRGIAVSGHHAAMRTILAWLDRWESGDSSAWPYWITRDELRTRRPTPSTPRRPSWCY
                     GTAGLARARQLATLTLGDTRRRIKAENALVVALTDADQLRDTTDNGLCHGFAGLAHLAA
                     RVAEDAHATTVDRIRAAIPALLDKIHPLGAALGSGNPGLLDGAAGVALALIAPSTATSP
                     RSAWDSCLLIA"
     gene            14224..16305
                     /gene="fxlM"
                     /locus_tag="AB852_RS35740"
                     /old_locus_tag="AB852_35170"
     CDS             14224..16305
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="AB852_RS35740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35170"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_073795375.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.8e-28, bitscore:
                     93.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 2.4e-48, bitscore: 158.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSDRWQQHNITFVDRSHAQLVIAERLAPTLITAEATGQLSGWWF
                     MNKQPWPLRYRADEPAPAVESLLDNLVGEGSVVSWLPGTYEPETDAFGGRAAMDAAHEL
                     FHSDSRHLLTYQPGPKHLRRRETAVLLVSAMMRGAGLDWFEQGDVWSKVAALRPATYPL
                     PAERTASLAPAVRKLMTVDARSLCNPGGPFHGHAEWVTAFELMGATLADLADHGGLTRG
                     LRAVLAHHVIFHANRAGLLRDDQSALFNIAREVVMGTSDNTASASGAAADVDSVGAVNT
                     DTITTDSAEAERLRNALVDQILANGHARTPAVEQALRAVPRHVFVPDATLEDAYANAPV
                     HIKYDTEGASISCASQPGVVALMLDQLDVRPGERVLELGAGSGYNAALLAHLVGEGGHV
                     TTLDVDDDLVEGARAHLTAAGVTNVEAVTRDGALGYAEGAPYDRIIATVGAHGVPHAWL
                     DQLAPGGRLLVPQRLKGSVARSIAYEQRDGRWVSLGSEMNTFMPLRRGIADDDRRVVPL
                     SADGTVRLQAPAGQDIDADALARVLEQPRTEEWTGMTVRAMESPEWMELFLTCSLPSGL
                     IRMLFPQGTKGGLLTEDPYPSSTAAVEKSAVTYLARRLLEKRTPEGGKLWEFGVIGHGP
                     GSDELAAKVADAIRIWDREYRGREATFEIQHLAAPPIEQRPGLFALDTPLNRIVVDWQ"
     misc_feature    14254..14268
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            16383..17483
                     /locus_tag="AB852_RS35745"
                     /old_locus_tag="AB852_35175"
     CDS             16383..17483
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347623.1"
                     /locus_tag="AB852_RS35745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35175"
                     /product="hypothetical protein"
                     /protein_id="WP_079185172.1"
                     /transl_table=11
                     /translation="MDPHGPTAQRFPLVARFRPACLPLPQRVHALVDLADAAVRKADQG
                     LASAVYNQAALIASDLGLPDLARELCHQQAAAYLHSCPLPGMSAIRGLEPVVNLARLQI
                     RAGRADEGRQRLLDLYGAVEAGAHARFDGVEIPADLTATEADRQEVRAWLWRVLLADGT
                     RTLTTAGRWAEALTHIESHRGVGQRMLDGRQVAVLAALVSGDTASAAELLHDTTPGDPW
                     EQLVTACLTVLCRRDAQQPIDDHLTELIAAYLQRPTEPGMIVFDIRLGLTLLDAVGPAE
                     APARQRMVQELHRRTVEAEDGYAAREVLAHPLFLTLATDREAQDCRALVRVCALGAGAI
                     PDHLHSELAAALRASDKVIGDSLVLR"
     misc_feature    16446..16448
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17484..19187)
                     /locus_tag="AB852_RS35750"
                     /old_locus_tag="AB852_35180"
     CDS             complement(17484..19187)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347624.1"
                     /locus_tag="AB852_RS35750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35180"
                     /product="mobilization protein"
                     /protein_id="WP_073795376.1"
                     /transl_table=11
                     /translation="MIARISSGKSTAGLIRYLFDTKKAKDHTDPHLVASWDGFAPDPGR
                     AEDFDATKKLLVADLDLRVKQARRLGRAPEQHVWHCSVRAAPEDRELTDDEWAQVARRI
                     VHATGIAPEGDPDGCHWVAVRHAPDHIHIAATKVRGDLSSVRHWHDYRNADRELVAVEK
                     EYGLRQVARGDRTAAKRPTRAEQEKSRRRGRGTTAREQLRTTVRTAVAAASTIEEFAHL
                     LSQIDGVITQVVYFPSGDVRGYKIALKGDTNAQGDPVWFSGSELAPDLSFPKIRERLNA
                     IEPATDQQLNRGRPDPWHQTITMIELIPHHLDQADDEASQAHLHAFGEVLDALPLLAPR
                     QLRTQLRDAATAFERATRSRIRAEQHQARALRSAARAMLRQPPPKDGALLAMLLDAAVL
                     VVIAASRWHQRHHHDQQVEAARQALLHLQIAYDQAAVAPLAALAQGRPSQQIVERHIHH
                     VRRAVPSQAERVLADPAFDALITVLSDSEAAGHDPDQLLRQATDQRPLDDARNPARVLT
                     WRVQRITTGQALSSRDRVAGVRSTVKLRTSAPAHSAEFTPSQPSAPGRRR"
     gene            complement(19184..19705)
                     /gene="mobC"
                     /locus_tag="AB852_RS35755"
                     /old_locus_tag="AB852_35185"
     CDS             complement(19184..19705)
                     /codon_start=1
                     /gene="mobC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347625.1"
                     /locus_tag="AB852_RS35755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35185"
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_073795377.1"
                     /transl_table=11
                     /translation="MAEGLGHQGAPEGEASASPTVSPLPRAAEAAALHRVARRRRRDPS
                     GQRKQRVDARYSVDEKKAILARARSLNIAGAHYVGAVVMAHIHGDLALPGQRTPLDDYI
                     DELTALRGEVARIGNNINQIARKLNAGGHPQPGDTELLAQAERTLADTGTTVRRIAAAA
                     NQALMRKEGQ"
     gene            complement(20089..20817)
                     /locus_tag="AB852_RS35760"
                     /old_locus_tag="AB852_35190"
     CDS             complement(20089..20817)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578919.1"
                     /locus_tag="AB852_RS35760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35190"
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_073795378.1"
                     /transl_table=11
                     /translation="MATSAVPPAPAYPDTGHRMTGWDRAAILSLGAAACALSYDALQQM
                     AVAIHVRGLLTYLFPLVIDGFIAYGVRALLVLRTAPFRARLYVWALFGTATCASIWANA
                     LHAVRINQQNPPGTLHLSDLTVGILSTLAPLALAGAVHLHILITRETTTDTAPPPVTLP
                     DPEQLTSEPAATRRGGRPADATLDELVEIGRIAVAEHGRLSRSTVLQAIRDKGLKVGGE
                     RLTEVMNTLRAESETSFVDG"
     gene            complement(21176..22438)
                     /locus_tag="AB852_RS35765"
                     /old_locus_tag="AB852_35195"
     CDS             complement(21176..22438)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347627.1"
                     /locus_tag="AB852_RS35765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35195"
                     /product="DUF3631 domain-containing protein"
                     /protein_id="WP_073795379.1"
                     /transl_table=11
                     /translation="MEHAPTEPYSTPTKPIWPPVAVPGRPGHQGGQDGEPSALAEVSPG
                     EAVLDPEPTAGSGLLDELRAQIARFVILPSQEALDAVTLWVVATHLQPAWQHAPRLAVV
                     GPAKRCGKSRLLDVLTETVHEPMLTINTTPAAVFRSITEEPPTLLVDEADTIFGTPKQA
                     EKNEEMRGLLNAGHQRNRYVTRVVGNDHTPHKFATFAMAAIAGIGDLPDTIMDRAVVIR
                     MRRRAEGETVKPFRSRRDIPALHELRDRIAAWGRPLLDEAADLEPELPVEDRAADTWEP
                     LVIVADLSGGSWPRRARTACARMVAAEERAEEENPSGAKILADIRRIFHAKGDPESLST
                     DDLLFALNGDAEAPWAEWGRNGLTPRGLGALLRDYTIASGNVRVGEIQRKGYTRNKFAD
                     AWRRYCPTVHPIDAGPVTAEG"
     gene            complement(22702..22932)
                     /locus_tag="AB852_RS35770"
                     /old_locus_tag="AB852_35200"
     CDS             complement(22702..22932)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961488.1"
                     /locus_tag="AB852_RS35770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35200"
                     /product="hypothetical protein"
                     /protein_id="WP_073795380.1"
                     /transl_table=11
                     /translation="MRGDVTSGQPKGMSREELLALPVAVDLDTSNRALGLGRSKGYELA
                     KRGAYPCKVLRLGNAYRVVTADLLSLLGLAA"
     gene            23028..23717
                     /locus_tag="AB852_RS35775"
                     /old_locus_tag="AB852_35205"
     CDS             23028..23717
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061649.1"
                     /locus_tag="AB852_RS35775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35205"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_073795381.1"
                     /transl_table=11
                     /translation="MTQRDFDDEEDDFPEWVDRIKANVAGEVRRRRKGRGWSAQDLADR
                     CEELGHPIPRNVIANMESGRRASLPLVDVMVLAAALETYPVHLIFPVGYIEKTQELPFQ
                     ELVPTWDALRRFTGEEDVFENDPGMVSEFEHHTLLVRTALAALDEEKQARFDTRTAASR
                     AQRENAERQQAEYADRAIAAKYQLRVLRREIREDGATPPDLPPALHDVDPPGTNPETDT
                     DPTEESA"
     gene            23714..25315
                     /locus_tag="AB852_RS35780"
                     /old_locus_tag="AB852_35210"
     CDS             23714..25315
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019064590.1"
                     /locus_tag="AB852_RS35780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_35210"
                     /product="site-specific integrase"
                     /protein_id="WP_073795382.1"
                     /transl_table=11
                     /translation="MKGSTHRRCYCRDVHTGKPLGKKCPQLSSRKHGSYSIRQELPPRE
                     DGTRRSFSRAGYDTLKAAQADLDHVRALLGLADTDDPEGLALIAAMLEEIGDEKAPLPD
                     VEETRRRLNAGQDLVGSLTVAEWLDRWLAGKRIRKSGISRYETDIRVHLKPHIGHRRLD
                     RLRVSHLNDMFTAITDANAEILEQNVQRRAAVDELAAIPWKGAEHRARRKALKVAIDAM
                     PPFRRVTGPATRQHVKATLRAALNDAIGQQIITFNPAAHVELDPVRKPKALVWTNERVA
                     KWEQTGEKPSPVMVWTPAQTGAFLDFVAEDRLYAMWHLIAFRGLRRGEACGQPWSETNL
                     DTHSLTVSSQLVQDGWAVETSEPKTDSGFRVIALDDDTVNVLKEHRERQDADREEWGTA
                     WVETGMVFTQEDGTWLHPSKVTDLFERLVAASGLPPIRLHDLRHGAATLMLAAGIDVKI
                     VSDTLGHSDTRITRDIYQSVLPHVGKNAAEATAKLVPLQRKAEATEARKAAKKAASKAK
                     AEARTKKKGKRKKGEK"
     tRNA            complement(25444..25517)
                     /anticodon=(pos:complement(136155..136157),aa:Thr,seq:cgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AB852_RS35785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="AB852_35215"
                     /product="tRNA-Thr"
     gene            complement(25444..25517)
                     /locus_tag="AB852_RS35785"
                     /old_locus_tag="AB852_35215"
     misc_feature    26009..26024
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    26180..26198
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.53"
                     /tool="antismash"
ORIGIN
        1 tcacgcctat gggagtccct gatcgccatg ggaaggttgt gtgacctgga cggcgacgac
       61 acgtggcgct tggtgattct tgactgtatc gttccctact tccgctcgtt atccgcaagg
      121 atctctcgcg attttcacgt cgagtgtgaa gacattcggt cggccatggt ggcaaccgcg
      181 ttggaagtgt gggacgaaac cgttagggga gtcgcaccac gtcacgtcag ggatcggatg
      241 gtcaaggcag ccttcgaggt ggccttccgg ctggggagcg ctacctcttc tgagtactcg
      301 atggacgacg tcgagatatt tgttcaacct gaaggctctt ttctggactc cacactgaag
      361 gcttcatcga tcatcgatgc cagcaatatt catgatgccg atgtcgcgga gcagctcaga
      421 ggtgaacgaa tcggggaatt gtttcagcta cgtggttgct ccgaaaccgt tcgagatttt
      481 catgacgaac ttcgaactgg cacccgttca gggtcaatca accagacggt gaggaccggg
      541 ctttctcgat cctggttctc tgacccaaac ctctactact acgtctccga cctctacccg
      601 tcgttcatcg gactccggga agccgcagac gtgatggata tagccgagtc tgccgcgtat
      661 cggctcatca gggccggaca gtttccattc cccgcagcac gagcaggacg aggctacaag
      721 atctccgtga aggccctcat gctcttcaaa agtattccga atcccatcgt ccatgtcgac
      781 gacgtggaaa acggcgccct ccacgcaggc ggtgctgcac tgtgatccat tgtgccgtca
      841 ggggagcttg ccacggccgg tatagaccca gagcccaccc aaattcggga gtcgaaggtt
      901 tggcgccacg cgctgatgtg catcgactcc cccgttggtc ccgtcttccc tgatcagagc
      961 actacagacg gtccagtgcg acggggctgt gtggcaccgt cggcttgtcc gcgcgctccc
     1021 accggtccag gctctgcgca catgcgctcc ccttgggttg gccagcgcaa agtcagggct
     1081 cccgcccatc gagaaaccgc ccccgaacag cgaaaaaccc caggtcacgg cgagtgagtc
     1141 ctggggtcct tcagagccgc cttcgggatt cgaacccgag acctacgcat tacgagggcc
     1201 tgcaagatca tccccggtgg tgctgggcgg tgccgcagaa tcctgtttcc gctgatcaga
     1261 agcttgtagc cttgatcggc gtgatgcctg gtccgccccc gtgtcactca gtccgctcac
     1321 gcagcgctca cgcagatcgc aaccgtcgca ggcttgattg gcggcttcag atcaccgttg
     1381 agggcgagtg cttgttcagg taactcttga aggtcttcct gatctctgcc tggagataac
     1441 ccgcctgcgg cgagttgggc accacgtcac gctcgaagcc tcgcttccga gcatcgaggt
     1501 acctgacgat gctcggtgaa ccgatgttgg agacgaagag ctcgctctga gtacggatgt
     1561 cggcgcgcaa gccctcaaag ttccgcgcca gcccgatgcc gaggttggac acgtagtact
     1621 tgcactcgac gatgaggatg ctctgacttc cgcgcggctc aacgccctgt tcacggctca
     1681 aggccgcttc ctcggcaggc agcaccaaca cgtcgcattc gtggagaaca cctgacgagc
     1741 cggtcacgaa gacgccaagg tggacttcga gggcgggggc gccgtcgaac tcgatcacag
     1801 cgtgggtgaa gggctgactg tccccgtaga gatgacccgg ccctgtccgg aatacgaggt
     1861 tattgacctt cgccccgtag acgtcttcgt acctgacggt ggcaccatga cgactcgcgg
     1921 tagccacgat cagtgagaag atgaatcctt cgtagacatc ggacggcttc gacgcggcat
     1981 catacgaaat cgtccccgcc gccagaaagc tcttgatctc cccgatcagc tgatcgaccg
     2041 cagtcacctc cgcacctccc gcgacacctc agtcaccagt tgactgactc gttcacgccg
     2101 ttccgtgggc acccggttca ccaggatctc cgttcggctg cgacgcgacc gagttctttc
     2161 gtctggttcg aacacgactc cctcaaccat ggtgcggcgg ccgtcgtcac cgccgggctc
     2221 cgcctgaagc gtcttcagcg tctcccgttc gatctcaggc agttcgacaa gcacccgcct
     2281 caccgcatca agcaaaagct ggacacgttc ctggtccgtc atggctcgcg tagcgataac
     2341 cagcgtccct cgcttacgcg acgcctcata ctcgctggcg ccgagcaggt tccgatccac
     2401 cacctcgtag cggagcgctg ccgatgccgg cgttgcggca tgggactcat caccgcggcg
     2461 ttgggggcgc cgacgcagga ttttctcctc tggcacacct gctgcgatcg cggcatcgac
     2521 atcgtcgaga acccaggcca atgcggttcc ttgtagcgct tcgcggagcg cctgctcagt
     2581 acggcgcagt tcgaacgggt tcacgcttcc cccttgccta gaagacctac ggccgttgat
     2641 gctcatcgcc ttgtggcgcg cctgtcactc gtgacaggcg cgccatgccg agtatctgac
     2701 gactggacgg tggtgtcgcc gcctggaatg gcaggtaacc gattccccag accagaggcg
     2761 cccggccttg aatacccagg cgccgggtcc accgtggtac cgcccagtcc cctcacgcag
     2821 taaggatgtt cattccggct tggcaagcgc gatcagggac tcccacgacc ccttggcgcc
     2881 cttgatgatc ttctcggtcg cgaagatgta ccgccatgtg ccgaactcgc catagtcccg
     2941 gacgaagcgc gcccaatcct ctgcagctcg ccgcttctcc agcacctcgg gatcattcgc
     3001 tcggtcgttg gccttgccct ccacgaccca gtacgttccc tcgttgtcga ggacgatgaa
     3061 gtccgggtag tacttcttcc cgttgtcccg ctcgatccaa atggggcccg ggtcgtagtt
     3121 gcgcagccac cactggacgc tggggctcgc gtcgaacagg tgcgccaggg cgtactcggt
     3181 actgccggcg tcgaaggagg caaccggttc gactgagtgc tcccagccct cgtaccaaag
     3241 gtccttacgg aaatccgccc acttgctgac gacgttcgag ggcatgggcg gcgggggaac
     3301 agtcgggacg tctaccggcc ggaaggcgta agtgggctgg agcttacggg tgtcgtaggc
     3361 ggtcttgacc aactctccga gggaagttgc tgcctgggcg gcacgcagtt cactccactc
     3421 gtgttcctgg tcttccgcgg tgacgccggc tcccgccaag aactcgcgga caacacgttc
     3481 ggccgctcgg gattcggcaa gcgtctcctc cacgtatccg atgttccaga tccgcccaaa
     3541 gagatcgttg cggagctcag agatcgagat gaacttctgg gtggcgtcaa ccgattcggc
     3601 tgccgtcacg aacgtgccca ccttgctgtc caggccacgc tgggcgtcga ccgcctgccg
     3661 caccagcggg accttgaact cgtgcttgta tgcggcaccc tcagaccgca cggccgcatt
     3721 gtcgatgtag ctgaaggaga aacgaacagg aagaatctcc cgctcacgcc tggggaagcg
     3781 gatcgtcggt gcaccgggga ccttggtgcg gagcgttgta acggccttcg cgtcccgctt
     3841 gccttgggcc atgacagcgt caaacgactc cacatgcagc agcggagagc cgtccaccaa
     3901 gtcgtcgccg atgacacgcg ggcgtgacgt aaaggtcagg atctgctgct catcgccgct
     3961 gctcggctgg ttcgcaacag gggccggctg cggacggccc ttgtccaggt caccgccgtc
     4021 agcgggcaga acctgctgca acagcgcgtc cttgttggcc agcagctgcc ggtaggactc
     4081 gtgggcaaca aggtcaactg tgtccaccat gggagtgccg accctccgcc catagggcag
     4141 ccgcagccct cgaccgagga cctgctccgt cagagtctcc gaagcaagag ctcgcaggcc
     4201 gacgatcacc ccgatgttct tgacgtccca gccttccttc agcttgttca ccgagaccac
     4261 gacgcgtacc ggcgagtcgg cctcttccac cgcagccagg gcccgcagtg cggtgtcgct
     4321 cgactgcgac gtgatggtga gcacttgtcc ctcaccggga aacatgtcat cggctgtcag
     4381 cctgtttgcg acgcgctcgg cgtcagggat gtcacggcat accacgaaca acacggggtg
     4441 cacgggggtc ctgccctgtg cttctgccca ggcagtccat gcggcgtcct ttatccgcag
     4501 cagatggcaa gcatcggcaa ggaccgtgct ctcgtccttc cggccatccg ggcggtagac
     4561 gatcacaggg atcttcacga agccgtcggc aatggcctcg gcaagggagt attggaagat
     4621 cggcttgaca cctggtgcag gtgtcgcggt gagtccgacg accgcccgcg cgcccagttc
     4681 ctcgatggcc tggttgaatg acttggctct tgagctgtag acgtggtgct cgtccgcgat
     4741 gacgacgagg tcctctacct gctgaaggtg ctggtagaga cccgtgccga tgaactcgtc
     4801 tcgggcccgg acttttctgg acgtcttgtc gctgggccgg atcaactgct gcacgttgaa
     4861 gacgaacagc ttcgtgatcg tgtcgtcgtg cagggcatcg cccacctgtc cccgggagaa
     4921 gttttccgag gtgatcacca acggctcggc atcgctgccg ttcacgaact tcgcatgccc
     4981 gggagtgaag ttggcgaccg tcttatcctg gatcgtcgtc cctggcgtga cgaccaggat
     5041 gttccgaact ccctgggctg ccaggtagtc caccaggccg gcaaggatgt acgtcttgcc
     5101 gacgcccgtc gccaggtcgc acaccacttc gcggccgttc ccgtccgcga tcgcttcggc
     5161 aaccgcgcgg acggccgctg cgttgggtgc ccgaaggtcc aacctcgcgg cgatgtcgtc
     5221 cacgagcgag gcatcgtagt cgatccaggt catcgcacag ccttcccgcg acgcaccaga
     5281 tcgcgaggcg ccttaagcac cttggaccct cggctcagct ccgcaacgag actctcagct
     5341 tcgggcgtga tgcccctgcc gacgatcact gctcgttctc cctcgtccaa atgcccaata
     5401 acgcctcggg ccacgacctc gtccacgacg ccgtcgacaa cggccagccg ggcacgtcct
     5461 ttcgtaccgc agaacggccc accgtccgcg ctgtcataca tgaagcccag ctgggctgcg
     5521 acgacggcag taaagtcttc gcccttgacc caatccgcga ggaagactcg gccatcggcg
     5581 atctcgaacg cggacggcga tgccttgagg ctcctgaagc cgcctccgcc ttcccatcca
     5641 acggtcttcg tgatgccccc cgggtcgtcg ccggcaacga ccttctccaa gcggggccga
     5701 gtgaaggtct cagccgtctc ttcgaggatc tcggcagtca cccaccggcg tcccatcttg
     5761 tgcgctaccg cagcggtagt gcccgaaccg gcgaacacgt cgacgaccac gtcgcccgga
     5821 tcggtagcaa tctggatcac gcgcttcaag agagcctcag gcttcggggt cgagaagatc
     5881 cgcgaccggt cgaagagctt ggtcacctcg gccttcgcct ggcggttgtc gccgacctcg
     5941 tcgtgcgtcc agaaagtggt aggcacgagg ccacccagtt ccgactggaa tcgctttctg
     6001 aacgggaagg tgcgccccgt cttcccccac cagagccggt tgtcctcacg tagtgagtcg
     6061 aaagtctccc ttgagcacga ccaccaacgg tttcctctcg gggaaaacac gtccccgtgc
     6121 ggaccgacca cctcatagcg tccgtcctcg tacgcatggg aagccgtgag atccgacctg
     6181 cgccaggggc cgcgagggtc attgtccggg ttccagaact cctggtcgct cagctccgtg
     6241 cgatcgatct tgttgaggac aagatcgctc ttggagcggg cgtagacgag gagatagtca
     6301 tggaccgagg agagatgctg ggctgagtta ttgcgcgcgt ggatcttctg ccagacgaca
     6361 gtcccgacga agttgccacg tccgaagacc tcatccatga gaacgcgaca gtaggccatc
     6421 tcggcatcgt ccagatgaac ccagactgat ccgccagggg caagcaggtc acggataagc
     6481 aggagtcggt cacgcatcat cgtgagccag acagagtgct caagcgcatc gtcgtagtgc
     6541 tggaaagcct ggcccgtgtt gaacggcgga tcaatgtaga cgagcttcac cttgccgcgg
     6601 tagtgatcgc cgtactccgg gttacggacc agggccagca gagcgtcgta gctgtcgcca
     6661 tgaatgagaa ggttgtcggc tgccgtgccg gtgacatcgc cagccttgcc tgtttcctgc
     6721 agtaggcgga cttctgtaac ccgcgggtct tgtcgtgaga cccactcgta tccgccgtcc
     6781 gctgtgtttc gcagggcctc atccctgccg acccacgaca gggtcagacg cccactcgtc
     6841 acccgcgacc actccctttt gcactcgatc ggccccggcg cccggcgcgg accacaacac
     6901 tcgctgcaac cgtaccggcc gctgccgaca gtggcggtcg gttggatacc gtcggcgccg
     6961 cagttccata gaggggcacc acccgacccg ggcaccatgt gccgcacctc ataggccgca
     7021 gccgaccctg tatcgactgc gggtcctgct caggcgtgtt cctcaaggag gcgatcaccg
     7081 ctattggtca gcggatcgct cggaccatca cgatcagaag tggcgaggct ggcgacggtt
     7141 ggctccgggc aatgttcttg tacccccacg acctgtagag cgcgtggacc ttgccgtcgc
     7201 cagcagccgg attgaccatg agtgtgacat gcatctcatc gcaggttgtg gcgaggaggg
     7261 cgtcgtggat gcggcgagct gtacccgtct tgcgccaagc gggccggacg ccgatctcct
     7321 tcagggccag ggccgggcgc tcggtgtact tctcggccgg ctcgggagtg gtgcgctgcc
     7381 agtagcggtc gccgcgttcg atggtgttgc cgtaggcgta gccgaccggc tcatcgtcgg
     7441 cgtacgcgag gaccgcgacg aagcccggtt cggtgccgtg gcggtccagc cgttcgccga
     7501 aggtggtgac cgcgtaattc gggaggtgga ggagcggggc gcgtacgtcg gcgtagacgt
     7561 cgaggaggtc gccgcggacg gggtcgaggg tggtgaaggt gcgcagttcg atggtggggg
     7621 ccgtggtcat gcggtagtcc tccaggtggc ggcgtgctcg gtccaggtct gcgcggtggt
     7681 gctgccgggg gcggtggcgc gcagggcggc gccgaactcc tggagcatgc gtgctacccg
     7741 ggcgtggtgg gtggcgacgt cggtggggac cttcatcgcg gtggccgtgg cggcgtccgc
     7801 ggccccctgc gcgagctggg cgtgggcgag gcgggtcgtc gcgatggcgc gggatctgat
     7861 catgtggggg cggagcgcgg acaagcagcg gtgggcgtgg tactcggcgg tcgggtagtc
     7921 gcccagggcc aggttcgctg acagggccag cgagtccagc tcggcctggt cgtagaaggc
     7981 gagcatccac acggggcggt attcggtggg gtcggagcgc agcatggcct cctgcgcctg
     8041 gtcgaatgtt cgacgcatgc cgctgcggtc ctgggctgtg ccctggatgg ctccctgccg
     8101 ggccaggccg agggacgcga acagggggtc gcgccgggtg aggaagaggt tgcgggccac
     8161 gtcgttcgcg gcgagcgcgt cggcggggcg gccgaggtgc cggtacatgg ttccggtgtg
     8221 gctccagatg cggaacttga tcgcctggtc accggacatc tcggcgaggg tttgtgcctc
     8281 ccgcatgtgg gtcttggcat cgtcgtagcg ccggccgtcg atcgcggccc acatcgccga
     8341 ggagcggaac gccgctgcgg aggcgtacag gctgctgcgt acgcgctggg tcgcactgcc
     8401 cgagttctgg aggttcagtg cttcgtcggc gagggaggcg gctcgctgtt cgataccgag
     8461 ctgtccaccg tggcggtggt cgctggcgat gatctcggcg aagcgcttct ggagacggtc
     8521 gacgtcgctc atgccgatcc ggcgtggcga agcggtgccg ggtgacgccg cggcgacggc
     8581 ggccgccgtg atcccgccga cgagcgtgcg gcgcttcatg tcagggtcct cctgctgcgg
     8641 tggaaccagg gccgacggag tcctgccccg tggaacgaac cctaaagcgg tggcgggcag
     8701 gccggcgatc tcctcaagcg ccttgcgggt ggccgtcttc ggccacttca cacggccggc
     8761 cttccagccc cggaccgatg atccgtcgag ccctccggac cttccggtca actgctctaa
     8821 ggacctgttc acagcgtcgg cgaggctgtt ggagctgtag ccgtgctctt ccatccacgc
     8881 ctcaagaacg gtgttgcgcg tggcatccat cccggcacgg tagcgctcgc gtcgcccaat
     8941 cgtcaggtaa gcgctgggtc aaatcgccct aggtcgaccc gttgagcgca tgcctgatgg
     9001 tcctaaccag ccgaacggaa gccggggtta tctgggtgtc ggccgcccac catcccgggt
     9061 ggctgttgac ggcccggtcc gcacgctcac gtctcgcaag gggcggaccg ggcgccgaga
     9121 caacccgaag gctccatccc catgacgagt ctcaacacac ctgttcatgc cgcccgtgtc
     9181 gggcgccccg cctacagcca gaccatcccg tgccagccgt ccaccgctga gacctgccgc
     9241 aagctcgtcc accgtgtact cggtgcgtgg tgcctggatg aactcgccga cggtgccgtg
     9301 ctgatcgtca cggagctgat cgcgaacgcg tcgaagcaca cctcgtgcca cgacatccgt
     9361 ctgaccgtgg gacgcccaag cgcgtcgcga gtccgtgtcg gcgtcgtgga ctgggaaccg
     9421 gagcgcctgc ccgccgcagg ccacgcgaac cacggcgacg agtccggccg cggcctgctc
     9481 ctcatcgacg cggtgtcgga ctgttggggc tatgacctct acggctcgga caggtgtcca
     9541 tggggcaagg aggtctgggc cgagcttcag ctcaccggcg acggatcaac gacccgtcgg
     9601 ccacatccat cagtgaaccc accaaacaag gaggtagtca ccatgacgcg caacaccgtc
     9661 attcccagtc tcacccaggt ccgtccccag gcggcggaag catcggacgg cttcgacctg
     9721 gacgtctccc tcgtcgagat cgccgacccg gcggggctgg tcaacctgac cgacgacaac
     9781 tgcggcacca cctgcggtgc ctgcacgacc aacgtcgcct gacctgctct gtggccagtt
     9841 cggctggtgc cgccgccttc gtgcggcggc gccagccgcc cgttcccgca ccctacggag
     9901 gtggttcgtg gttaccgcga ccgcggcgtt ccgcgccgga acaactgccc ttgtgcgcgc
     9961 cgtcgcccag cctccgctgg tggtccctcc atggcccgac ctgggcgacg ggttgcccgg
    10021 tgccgcagca gatcaagcgg cgtggctgcg tgcggtctgg gcggacgagg acttcgccga
    10081 gaccttgcag cactccagcc cggcgctggc cacgcaagtg cagagtctgt gcacaggaca
    10141 acggcccgat ccacgggacc ttcggcgtgc ggtgctttcc gtgatccggt atttattgcg
    10201 ggcccagcac cgggcgactc cctttgggct gttcgctggg gtgacaaccg cgacgttcag
    10261 accgcgggcc agtgcgagct ggggcgaaga acacgtgctc gtcggcaagg ctggggcaga
    10321 gtggctggcc acggtcgtac agcgactgga gtcgtgcccg gaactcctcg aacggctgcc
    10381 cgtcgtcgcc aacagcaccg cgtcggtacg tggggaccgg ctcatcgtgc cgtttcagtc
    10441 tgatgaccga ggcgacgaga tccgcgctgt cgaagcatcg ctggacctca ccgcaccagt
    10501 gctggcggcc ctcaccgcgg ccgaggcgcc gatcagggtg ggcgtgctcc tgagcagact
    10561 cagggtggaa tttcccgagg cggggcctga gaagcctcgt cggctgttgg cggagctgat
    10621 ccgacggcgg gtgttgatca ccagcctgcg ggcgccgagc accgagaccg acgctctcgg
    10681 gtacctcgtc gaccaactcg acgccgtcga agcggagagc gttgcgccga tctcgaagac
    10741 ggtggccgag ctgcgtgcga tccgggcagc cttgggaggg tgctccacgc gcggcggccg
    10801 gtacagagcc gcagcccgga tgcgggagtt cgtgccagac gggaaccgcc accccgtcgc
    10861 gttcgacctc cgtctgaacg caaagctcgt gctgccggag gtggtcgccc aggaaatcga
    10921 acgtgcagcg ctcgttctga cccggttgag tgcgcgcccg tacggaaccg ccgcgtgggg
    10981 tgagtaccac cagcggttct acgagcggta cggcatcggc acgatggtgc cgctcaagga
    11041 ggtcgtggcg gacagcggcg tcggctatcc cgacggctac ccgagtatgc cgggcggtgc
    11101 tcgccggcct cgggtctctg ctcgggacga cgtactcgta cgcctggcgc agacggccgc
    11161 gctcgaaggc caggaggagg tcgtcctcac tgacgaactg atcgccgctc tcgatgtggg
    11221 accagacgaa cctcgggtgc cgccgcacct ggaggttggc gtacgggtgc actcggccag
    11281 cctgaaagag ttgcaacgcg gacggttccg gctggagatc gtgagcgtgt cacgaggtgc
    11341 cggcgtctct acgggccggt tcctcggtgt gctggaaccg gcagaccgcg aggcgctgag
    11401 caaggagttg gccgatctgc cgaccgcgga cggcgacacc gtgcccgcgc agctctcttt
    11461 cccgccgctg ctccccgaaa gcactcacgt cactcgcgca cctcaggttc tgcccaccgt
    11521 gatcagcctc caggagcatc gcgccccgga ccccgacgtg ctcaccctcg atgacctcgc
    11581 ggtcgcgtgc gacggacgcc ggatgtacct ggccgctcca ggccggggcc accgtgtcga
    11641 agccgtgggg atgaacgcgc tgaacctgcg tacgcacact ccgccgctgg cgcggtttct
    11701 caccgagctg tcccgcgctc agtgcgcgca ggtcaccgtg ctcgactggg gcgttgccgc
    11761 agcgatgccg ttccttccgc gcctccggta cgaacgtacg gtgctggccc cggcacgctg
    11821 gaggctggag tcgtctgagt tgcccagcgg cgccgagtgg gacgctgcac tggccagctg
    11881 gcgggttcga cggcggctgc cgcggcaggt ctatctcgtg gagggggacc agcacctctt
    11941 cctcgacctc gacgaggcca gccaccgaac gctgctccgc cagcacctcg accagccacg
    12001 caccgctgtg ctcgtcgaag ccccggagag gtacggctgg tgcgacgggc gcgcccacga
    12061 ggtcgtcctg ccgctcaagg cggtacggcc gacggcgtgg ccgcccctgc ctgcccccac
    12121 ctcggctcgt gcactctcac cagcacaaat gcagaccccg gccacttcct ccgttctcct
    12181 ggccaccctg tacggagatg cccgtcgcca ggacaccgtg cttgcccagc atctgcccgg
    12241 cctgctggag cggctcggca acccgccctg gtggttcatc cgcttccgcg accaggccca
    12301 gcacctccgc ctccgtatcg ccctccccca tccgggggca ttcggcgaga ccgcccgtac
    12361 ggtgagcgag tgggccgacg aactgcggcg ggccggcctg ctggccgatc tgcgctatcc
    12421 cacctcgtac cgcgagatgg gccgctgggg ttccggagcg gcgtggaagg ctgccgaaga
    12481 cgtcttccgg gccgactcgc gtgccgtggt gacacaactc gcgcagcgac agcgacccac
    12541 ccaacgaccc ctggtggcgg cccacaccat ctccatcgcc tccgccttcc tcggaagcac
    12601 ggaagccggg atgcggtggc tggtcgacca cattccaccg acggctccca ctcccgtacc
    12661 gcgcccgcaa ttcatggagg ccgtacggct ggccgacccc cgcggcgact gggcggcgct
    12721 tcgcagagtc cccggcgggg aagccatcgt gtccgggtgg gcggaacggg acgcggccct
    12781 tgccgcctac cggccccacc tgccgggccc ggacactcag ggaatcgccg tcgacgacgt
    12841 tctgacgtcc ctcttgcacg tccacttcgt acggcatgtc gcggtcaact tccccgagga
    12901 agaggtgtgc ctctacctgg cgcgcgctgc cgctctcgcc tggaccgccc gtacaaaggg
    12961 gaggccgtca tgaccaccca cccggctttc gacctggccg acgccatcgc ggcccagctc
    13021 gccgatcccg atgtgccccg gtcctgggca gtgcccgcgt acggacagca cctggcctac
    13081 ggccctcccg gcatcgcgct cctgcacatc gaacgggccg cgcggggcct cggaccgtgg
    13141 cagcgcgctc acgactggct cgccgccgcc tcccgccatc ccctcaccag cggtcccgac
    13201 agccacccct tctacggcgc tcccgccctc gcccatgccc tggcctgcgc ggcggacagc
    13261 ctccccgggg cctatcagag cgccctggac tcgttggacc gacggatcgt ggtcgacgtc
    13321 cggcgccgtc tggatgccgc ccaccgccgc atcgacgccg ggcgcctgcc gcagctcgcc
    13381 gagttcgacg tcatccgagg actcaccgga tacggggcac atcttctgca ccgcagcccc
    13441 gacggcaaca cggtgcgtgc cgtgctcgac tactgcgtac gcctcaccga accgctgacc
    13501 gaccaggacg agaccctgcc cggctggtgg acggagaccg gcccctcggg taacccggac
    13561 gaccgcttcc ccggcggtca cgccaaccat ggcatggcgc acggcatcgg tggctcactc
    13621 gccctcctgg ccctggcagc ccgccgcggc atagccgtca gtggccacca cgcggcgatg
    13681 cgcaccatcc tggcgtggct ggaccgctgg gagagcggtg acagctcggc gtggccgtac
    13741 tggatcaccc gggacgaact gcggacccga cgccccaccc cgtccacgcc ccggcggccg
    13801 tcctggtgct acggaaccgc tggcctcgcc cgtgcccggc aactcgcgac gctcaccctc
    13861 ggcgacaccc gccgccgaat caaggcggag aacgctctcg tggtcgccct caccgatgcc
    13921 gaccagctca gggacacgac ggacaacggc ctctgccacg gcttcgcggg gctcgcccac
    13981 ctggcggccc gtgtcgcgga ggacgcccat gccacgaccg tggaccggat acgcgccgcg
    14041 atcccagcgc tcctggacaa gatccaccca ctgggtgcgg cgctcggaag cggaaatcct
    14101 ggcctgctcg acggtgccgc cggtgtcgcc ctggcgctca tcgcgcccag caccgccacc
    14161 tcgccccgtt ccgcctggga ctcctgcctt ctcatcgcct gatccgctga ccgaaggacc
    14221 ccgatgccgt ccgaccgctg gcagcagcac aacatcacct tcgtcgaccg ttcacacgcc
    14281 cagctcgtca tcgccgagcg cctcgcccca acgctgatca ccgccgaggc gaccggacag
    14341 ctctccggtt ggtggttcat gaacaagcag ccctggccgt tgcggtaccg cgccgacgaa
    14401 ccggccccag ccgtggagtc gctgctggac aacctggtcg gtgaaggctc ggtcgtgtca
    14461 tggctgccgg gtacgtacga gcctgagacc gacgcgttcg gcggccgggc ggccatggac
    14521 gcagcccacg aactgttcca cagcgactcc cgtcacctgc tgacgtacca gccgggaccg
    14581 aagcatctga ggcgccggga gaccgctgta ctgctggtga gcgcgatgat gcgtggcgcc
    14641 gggctcgact ggttcgagca gggagacgtc tggtcgaagg tcgccgccct tcgaccggcc
    14701 acctatccgc tgccggccga acgcaccgct tcgttggccc ccgcagtgcg caagctgatg
    14761 accgtcgacg cccgcagtct ctgcaacccg ggcggcccgt tccacgggca cgccgaatgg
    14821 gtcaccgcct tcgagttgat gggggcgacg ctcgccgatc tcgcggacca cggtggtctc
    14881 acccgtggcc tgcgcgccgt tctcgcccac cacgtgatct tccacgccaa ccgcgccggt
    14941 ctccttcggg acgaccagag cgctctgttc aacatcgcac gagaggtagt catgggaacc
    15001 agtgacaaca ccgcgtcggc cagcggggca gcggcggacg tcgatagcgt cggcgcggtg
    15061 aacaccgaca cgatcaccac cgactcggcg gaggccgagc gcctccggaa cgccctggtc
    15121 gaccagatcc tggcgaacgg ccacgcccgt acccccgccg tcgagcaggc tctgcgggcc
    15181 gtcccccgcc atgtgttcgt gcccgacgcg acactcgaag atgcgtacgc caacgcgccg
    15241 gtgcatatca agtacgacac cgagggcgcg tccatctcct gcgcttccca gccgggggtc
    15301 gtcgccctca tgctggacca gctcgatgtc cggcccggcg agcgcgtcct cgaactcggc
    15361 gcgggctccg gctacaacgc cgcacttctc gcgcacctgg tgggcgaggg cggtcacgtc
    15421 accacccttg atgtcgacga tgacctcgtg gagggtgccc gcgcccatct caccgccgcc
    15481 ggggtcacca atgtcgaggc cgtgaccagg gacggggcgc tcggatacgc cgagggggcg
    15541 ccgtacgacc ggatcattgc caccgtcggc gcgcacggtg tgccgcacgc ctggctggac
    15601 caactcgctc ctggtggccg gctcctcgtt ccccagcggc tcaagggcag cgtcgcccgc
    15661 tccatcgcgt acgaacagcg cgacggccgg tgggtatccc tcggcagtga gatgaacacc
    15721 ttcatgccgc tgcggcgagg gatcgccgac gacgaccgcc gtgtcgtccc gctcagcgcc
    15781 gacggcaccg tccggctcca ggcccccgcc ggccaggaca tcgacgccga tgccctcgcc
    15841 cgcgttctgg agcagccgcg caccgaggag tggaccggta tgacggtccg cgccatggag
    15901 tcgccggagt ggatggagct gttcctcacc tgctccctgc cctccggcct gatccggatg
    15961 ctgttcccgc agggcaccaa gggcgggcta ctcaccgagg acccctaccc gtcatccacc
    16021 gcggccgtgg agaagagcgc tgtcacctac ctggcccggc ggctgctgga gaagaggacc
    16081 ccggagggcg gcaagctctg ggagttcggt gtcatcggcc acggtcccgg cagcgacgag
    16141 ctggccgcga aggtcgccga cgccatccgc atctgggacc gggagtaccg cggccgggag
    16201 gccaccttcg agatccagca cctcgccgct ccgcccatcg aacagcgccc tggtcttttc
    16261 gccctcgaca ccccgctgaa ccggatcgtc gtcgactggc agtgacaacc gatagagaga
    16321 ggatggtgtc cgtcggccta cggcgggcgg gcaccgtctc caacccacgc ctcgggggac
    16381 tcatggaccc gcacggaccc accgcccagc gtttcccgct cgtcgcccga ttccgtcccg
    16441 cctgcttacc tctgccccaa cgcgtccacg cgctcgtcga cctggccgac gccgcggtac
    16501 ggaaggccga ccagggcctg gcgtcggccg tctacaacca ggccgcgctc atcgcctccg
    16561 acctgggcct tcccgacctg gcgcgcgagc tgtgccacca gcaggccgcc gcgtacctcc
    16621 acagctgtcc gctgcctggg atgagcgcga tccgcggact ggaacccgtc gtcaacctcg
    16681 cccgcctcca gatccgcgcc ggccgcgccg acgagggacg acagcgactg ctcgacctgt
    16741 acggagccgt cgaagcaggc gcacatgccc gcttcgacgg cgtggagata ccggcggacc
    16801 tcacggcgac cgaagccgac cgccaagaag tccgtgcttg gctctggcgc gtactcctcg
    16861 ccgacggcac ccgcaccctc accaccgccg gccgctgggc cgaggccctg acgcacatcg
    16921 agtcccaccg gggcgtcggc cagcggatgc tcgacggccg ccaagtcgcc gtactggccg
    16981 ccctcgtctc cggcgacacg gcatcggcag cagagctcct ccacgacacg acgcccggcg
    17041 acccctggga acagctcgtc acggcgtgcc tgaccgtcct gtgccgccgc gatgcccagc
    17101 agccgatcga cgaccatctg acagaactga tcgcggccta ccttcaacga ccgaccgaac
    17161 ccgggatgat cgtcttcgac atccggctgg gtctcaccct tctcgacgcg gtcggtcccg
    17221 ccgaagcacc cgccaggcag cgcatggtgc aagagcttca ccgcaggacg gtcgaagccg
    17281 aggacggcta cgcggcccgc gaggtcctgg cccaccccct cttcctcaca ctggccacag
    17341 atcgggaagc ccaggactgc cgcgccctgg tcagggtctg cgcgctggga gccggggcca
    17401 tcccggatca tctgcacagc gaactggcag cggccctgcg cgctagcgac aaggtgatcg
    17461 gggacagcct cgtgctccgg tgatcagcgt cggcggcccg gcgccgaagg ctgtgacggc
    17521 gtgaactctg ctgaatgagc cggagcgctg gtgcgcagtt tgaccgtgct gcgaacccca
    17581 gccacgcggt ctcggctact gagtgcctga cctgtagtga ttcgctgtac gcgccatgtc
    17641 agcactcggg cggggttacg ggcgtcatcc agagggcgct gatcagtggc ctgccgcagc
    17701 aactgatccg gatcatggcc agcagcttcg gagtcggaga gaacggtgat gagggcatcg
    17761 aaggcagggt ctgcgaggac ccgctccgct tggctgggga cagcacgacg tacgtggtga
    17821 atgtgccgtt ccacgatctg ctgggatggc cggccttggg caagggcagc caatggggcg
    17881 acggcagcct ggtcgtacgc gatctggaga tgcagcagag cctgacgggc ggcttcgacc
    17941 tgctggtcgt ggtggtggcg ctgatgccag cgacttgcgg cgatgacgac gaggacggcg
    18001 gcgtcgagaa gcatcgccag gagggctccg tccttaggcg ggggctgccg gagcattgct
    18061 cgtgcggcgc tgcgcagcgc acgagcctgg tgctgctcgg cccggatgcg ggagcgggtg
    18121 gcgcgttcga acgcggtggc ggcgtctcgg agctgggtcc gaagctgtcg gggcgcaagg
    18181 aggggaaggg cgtcgaggac ttcaccgaag gcgtggaggt gggcctggga ggcttcgtcg
    18241 tcggcttgat ccaggtggtg ggggatgagt tcgatcatgg tgatggtctg gtgccatggg
    18301 tcgggcctgc cccggttcag ttgctggtca gtggctggct cgatggcgtt cagacgttcc
    18361 cggatcttgg ggaaggacag gtctggggcg agttcggagc cggagaacca gacagggtcg
    18421 ccttgggcat tggtgtcacc cttgagcgcg atcttgtagc cgcgtacgtc tccggagggg
    18481 aagtagacga cctgggtgat cacaccgtcg atctggctga gcaggtgggc aaactcttcg
    18541 atggtggaag cggcggcaac ggcggtgcga acggtggtgc gcaactgctc acgcgcggtg
    18601 gttccccggc cgcggcggcg ggacttctcc tgttcggcgc gagtggggcg cttggcggcg
    18661 gtgcggtctc cacgtgcgac ctggcggagg ccgtactcct tctctacggc gacgagttct
    18721 cggtcggcgt tgcggtagtc gtgccagtgg cggacgctgc tcaggtcacc gcggactttg
    18781 gtggcggcga tgtggatgtg gtccggggcg tgccggacgg ctacccagtg gcatccgtcc
    18841 gggtcgcctt cgggggcgat gccggtggcg tggacgatac ggcgagctac ctgggcccac
    18901 tcgtcgtccg tgagctctcg gtcctcgggc gcggcccgga ccgagcagtg ccacacatgc
    18961 tgttcgggtg cccggccgag ccgcctggcc tgtttgaccc gcaggtcgag gtcggcgacg
    19021 aggagcttct tggtggcgtc gaagtcctcg gcccggccgg ggtccggggc gaagccgtcc
    19081 caggaggcga ccaggtgcgg gtcggtgtgg tccttcgcct tcttcgtgtc gaacaggtac
    19141 cggatgaggc cggcggtgct cttgccgctg ctgatcctcg cgatcactgg ccctccttcc
    19201 tcatgagggc ttggttcgcg gctgctgcga tccgacggac ggtggtcccg gtgtccgcca
    19261 gggtgcgttc ggcttgggcc aagagttcgg tgtccccagg ctggggatga ccaccggcgt
    19321 tgagcttgcg ggcgatctgg ttgatgttgt tgccgatcct ggctacctcc ccgcggaggg
    19381 cggtcagctc gtcgatgtag tcgtcgagcg gggtgcgctg gcctggcagg gcgaggtcac
    19441 cgtggatgtg ggccatgacg accgcaccga cgtagtgggc tccggcgatg ttcagtgacc
    19501 tggctcgggc gaggatcgct ttcttctcgt cgacgctgta acgggcgtcg acacgctgct
    19561 tgcgctggcc gctcggatca cgccggcggc gacgggcgac acgatgcaac gcggcggctt
    19621 cggctgctcg cggcaacggg ctgacggtcg gagacgctga cgcttctccc tcgggcgccc
    19681 cctggtgccc gagcccctcc gccacccccg gggcggaggc atccgtatgg gaccggccct
    19741 tggacggtcc agcggcatac cttgctgcgc tggtgaccgc agtggttgtc tcctggtggt
    19801 cgaaggagtg agggctgtcc gggtggggca tgtggtggtt ctcctcgggg tctgctcgtg
    19861 aagtgggtga agtcgtcgga cgggcccggg aaagccacgg ctacatccac tctgcgagtg
    19921 ctgagaccac tggcatgggg cggggagggc tcggtggcag gccaccttct cgtcgccatc
    19981 cggtaccgca gcccggaggc gtctcggttc cgtccgcgac aggtggtccg tggccggggt
    20041 ggtcggaagg ggttccgacc accccgtgcc tgttccggtg gcgtgcggtc agccgtcgac
    20101 gaagctggtc tcggattcgg ctcgcagggt gttcatgacc tcggtgagcc gctcgccgcc
    20161 gactttgagg cccttgtccc tgatcgcttg gaggacggtg gagcgggaga gacggccgtg
    20221 ctcggctacg gcgatccggc ctatctcaac gagttcgtcg agggtcgcgt ccgctggccg
    20281 tccgccccgg cgagtggccg cgggttcgct ggtgagctgt tccgggtcgg ggagggttac
    20341 cggcgggggt gccgtgtcgg tggtggtttc gcgggtgatg aggatgtgga ggtggacggc
    20401 tccggcgagg gcgagtgggg cgagggtgga caggatgccg acggtgaggt cgctcaggtg
    20461 gagcgtgcca ggcgggttct gctggttgat gcgtacggcg tggagggcgt tggcccagat
    20521 gctggcgcag gtcgcggtgc cgaagagggc ccagacgtag aggcgggccc ggaacggggc
    20581 ggtgcgcagg acgagaaggg cgcgtacgcc gtaggcgatg aacccgtcga tgacgagtgg
    20641 gaacaggtag gtgaggagtc cgcggacgtg gatggcgacg gccatctgct ggagggcgtc
    20701 gtacgagagg gcgcaggcgg cggcaccgag ggagaggatc gcagcgcggt cccagccggt
    20761 catgcggtga ccggtgtcgg gatacgcggg cgcgggcggt acagcggatg tggccatgga
    20821 ggtggagtgc tcctgggtgg tgcgtggggc tggtggtgtg gtccgtctta tccgtcttgg
    20881 ccgttgcacc cgcaggtcag ggccgggacg gcaggcaggg cgcggtgccg tcccggcggc
    20941 acggccgtgg acggatgggg tgcgtttgcc gtcccgtggc gcggggccgt gacctgcgcc
    21001 gatacggcgg gtactgctgg gacggcacga gacggatcgg gacgcggttg ggcagccccg
    21061 gggcgggtgg tgatcgtgtt tccgtcttgg gcccggttgc cgtcttggcg ggatgcctgt
    21121 tgacctgcgg gatgacggca gggacggcac ggacggcaat cggggcgggg ctgggtcagc
    21181 cctcggcggt gacggggccg gcgtcgatcg ggtggacggt ggggcagtag cggcgccagg
    21241 cgtcggcgaa cttattgcgg gtgtagccct tgcgctggat ctcgccgacg cggacgttcc
    21301 cggaggcgat ggtgtagtcg cggagcagcg cgccgagtcc gcgcggcgtc agcccgttgc
    21361 ggccccattc ggcccagggg gcttcggcgt cgccgttgag ggcgaagaga aggtcgtcgg
    21421 tgctgaggct ctccgggtcg cccttggcgt ggaagatccg ccggatgtcc gcgaggatct
    21481 tcgccccgct ggggttctcc tcctccgctc gctcctcggc cgcgaccatc cgtgcacacg
    21541 cggtccgggc gcgacggggc caggacccgc ccgagaggtc ggcgacgatc accaggggtt
    21601 cccaggtgtc ggccgcgcgg tcctcgaccg gcagttccgg ttccaggtcg gcagcttcgt
    21661 ccagcagcgg gcggccccag gcggcgatcc ggtcgcgcag ttcgtgcagg gccgggatgt
    21721 cgcggcggga gcggaacggc ttgacggtct cgccttcggc ccggcggcgc atgcggatca
    21781 ccacggcgcg gtccatgatc gtgtcgggga ggtcgccgat gcccgcgatg gcggccatgg
    21841 cgaaggtggc gaacttgtgt ggggtgtggt cgttgccgac gacccgggtg acgtaacggt
    21901 tccgctggtg cccggcgttc agcaggccgc gcatctcctc gttcttctcc gcctgcttcg
    21961 gagtgccgaa gatggtgtcc gcctcgtcga ccaggagcgt gggcggctcc tcggtgatcg
    22021 accggaagac cgcagccggg gtggtgttga tggtgagcat cggctcgtgc accgtctcgg
    22081 tgagcacgtc cagcagccgg gacttgccgc accgcttcgc cggaccgacc accgcgagac
    22141 gcggcgcgtg ctgccacgcg ggctggagat gagtagccac cacccacagc gtcaccgcgt
    22201 ccagcgcctc ctgcgagggc agaatcacga acctcgcgat ctgcgcacgc agttcgtcca
    22261 gcaggccgga cccggcagtc ggctccggat cgagcaccgc ctccccgggc gacacctctg
    22321 ccagcgcaga gggctccccg tcttggccgc cctggtggcc aggacgtccg gggacggcga
    22381 ccgggggcca gatgggcttg gtgggggtgg aatagggctc ggtaggggcg tgttccactg
    22441 ggcggctcct cttctggcgg tggcgggctt gcgcgccctt gccgctgggt tggttcgtga
    22501 caggccgatg ggggttgccg gggcctccgg cgttgcaccg ccggaggccc gctccgttca
    22561 ctgagtgaac gcggccggtg ttccgagtcg gaacaggccg ggcgttcccc gtgggaacac
    22621 ggacagtacg tccacacccc tgcacagtcc agcgattctg tgtcagctca gcgcagaacc
    22681 gcctgctacg ctccctgccc ctcaagccgc cagcccgagc aggctcaaca ggtctgccgt
    22741 cacgacccgg taggcgttgc cgagccgcag cactttgcac ggataggcgc cccgcttcgc
    22801 cagctcgtac cccttgctcc gccccaaccc gagtgcccgg ttgctggtgt ccaggtcaac
    22861 ggcaaccggg agggcaagga gctcctcccg gctcatcccc ttcggctgcc cgctcgtgac
    22921 gtctccgcgc atgcggcacc ccctcttcga tgcagccgtc ggcgaacgcg tccatcacgt
    22981 ccggctccgg gccacttcat cgataatcct caagctaatg tgtctgcatg acacaacgcg
    23041 atttcgatga tgaagaagac gactttccgg agtgggtgga ccggatcaag gccaacgtgg
    23101 ccggcgaggt ccggcgcaga aggaagggga ggggatggag cgcgcaggat ctggcggacc
    23161 gctgcgagga gctggggcac ccgatcccgc gcaacgtgat cgccaacatg gaatccggcc
    23221 gccgcgccag cctgcccctg gtggacgtca tggtcctggc cgccgccctg gagacctacc
    23281 cggtccacct gatcttcccc gtcggctaca tcgagaagac tcaggaactt cccttccagg
    23341 aactcgtccc cacctgggac gccctgcgcc gcttcaccgg cgaggaagac gtcttcgaga
    23401 acgacccggg aatggtgtct gagttcgagc accacaccct tcttgtccga accgccctcg
    23461 ccgcactcga cgaagagaag caggcccggt tcgacaccag gaccgccgcc tcccgcgccc
    23521 agcgggagaa cgccgaacgc cagcaggccg agtacgccga ccgggccatc gccgccaagt
    23581 accagctccg cgtcctccgc cgtgagatcc gcgaggacgg cgccaccccg cctgatctcc
    23641 cacccgcact ccacgacgtc gacccacctg gaaccaaccc cgaaaccgac accgacccca
    23701 cggaggaatc cgcttgaagg gctccacgca ccgccgctgc tactgccgcg atgtccacac
    23761 cggcaaaccg ctcggcaaga agtgccccca actgtccagc cgcaagcacg gctcgtactc
    23821 catacgccag gaactcccgc cccgcgaaga cggcacccgc cgctccttca gccgcgccgg
    23881 ctacgacacc ctcaaagccg cccaggccga cctcgaccac gtccgcgccc tcctcggcct
    23941 cgccgacacc gacgacccgg agggcctggc gctgatcgcg gccatgctgg aggagatcgg
    24001 cgacgagaag gcgccgcttc ccgatgtgga ggagacccgt cggcgtctca acgcgggcca
    24061 ggacctcgtc ggcagtctca ccgtggccga atggctggac cggtggctgg cgggcaaacg
    24121 catccggaag tccgggatca gccgctacga gaccgatatc cgagtccacc tcaaaccgca
    24181 tatcggccac cggcgcctcg accggctgcg cgtgagccac ctcaacgaca tgttcaccgc
    24241 catcaccgac gccaacgccg agatcctcga acagaacgtc caacgccgag ccgctgtcga
    24301 cgaactcgcg gccatcccgt ggaagggcgc ggagcaccgg gcccgtcgca aggcgctgaa
    24361 ggtcgcgatc gacgcgatgc cgcccttccg ccgcgtcacc ggccccgcga cccgccagca
    24421 cgtcaaagcc actctccgcg ccgccctcaa cgacgcgatc ggccagcaga tcatcacctt
    24481 caaccccgcc gcccacgtcg aactcgaccc cgtccgcaag cccaaggccc tcgtgtggac
    24541 gaatgagcgc gtcgccaagt gggagcagac gggcgagaag ccctcacccg tcatggtctg
    24601 gacaccggca cagactggcg cgttcctcga cttcgtcgcc gaggaccggc tgtacgccat
    24661 gtggcacctc atcgcgttcc gcggtctgcg tcgtggcgag gcgtgcggcc agccctggtc
    24721 ggaaaccaac ctcgacaccc actccctcac cgtgtcttcg cagctcgtcc aggacggctg
    24781 ggctgtcgag acctccgaac ccaaaacgga cagcggcttc cgtgtcatcg cgctcgacga
    24841 cgacacggtc aacgtgctca aggaacatcg cgagcgccaa gacgcggacc gcgaggagtg
    24901 gggaacggcc tgggtcgaga ccggcatggt cttcacccag gaagacggca cctggcttca
    24961 ccccagcaag gtcaccgacc tcttcgaacg cctcgtcgcc gcctccggcc tcccgccgat
    25021 ccggctgcac gacctccgcc acggcgcggc caccctcatg ctcgcggctg gcatcgacgt
    25081 caagatcgtc tccgacaccc tcggccacag cgacacccgg atcacgcgcg acatctacca
    25141 gagcgtcctt ccccacgtcg gcaagaacgc cgccgaagcc accgccaagc tggtcccgct
    25201 acagcggaag gccgaggcga cggaggcccg caaggctgcc aagaaggcgg cgtccaaggc
    25261 gaaagccgag gccaggacca agaagaaggg caagcggaag aagggcgaga agtagggcac
    25321 ggaccgctcc gctcacgcat cgctcacgca agccatctcg cggcaccccg gccgtgtgac
    25381 gcgccatgcc ccgaaaaagc gaaaaacccc aggtcacggc gagtgagtcc tggggtcctg
    25441 cagagccgcc ttcgggattc gaacccgaga cctacgcatt acgagtgcgt tgctctggcc
    25501 atctgagcta aggcggctgg cgtctgcacc accggtgccg gggtgcgcga cgcgccaatt
    25561 ctacacagat tcctgagggg gccggaccac ccccgggcag gggtggtccg ggggctatga
    25621 gcagcgcttt ccgtcggcgg gaggggtgcc ggtgaggagg tatcggtcga tcgtggagtc
    25681 gacgcaggtg gacccccggc cgtacgcggt gtggccgtcg ccctcgtagg tgaggagggt
    25741 gccggagtcg agctgggcgg cgagggcctc ggcccagcgg tacggggtcg ccgggtcgcg
    25801 ggtggtgccg acgacgagga tcgggtcggc gcccttggcc tcgatgcgct gcggcccacc
    25861 cgtcgcgccg aacggccagt acgcgcagtt cagcgccgac caggccagcc cctcaccgaa
    25921 cacgggtgac gccttctcga aggcgggcac cgcttcggcg gcctcggcgg gcgtcgtgaa
    25981 cgccggaggc aggtcgaggc agttcacggc ggcgttggcg aacatcaggt tcccgtactc
    26041 gccgtccgac ccccgttcgt agtagccgtc cgacagggcc agcagccccg taccgtcgcg
    26101 cttgtcgatc ccggccgtca gcgcggagcg cagccggggc cacgcgccct cgtcgtacat
    26161 cgcggcgatc accccggtca tggcgagcga ttcgccgagg cggcggcccg gcttgccggt
    26221 ccggacgggt tcccggtcca gcgcgcgcag gaacgccttc agtttcgccc cggccgtcgc
    26281 cgcctcccgg cccagcgggc aagtc
//
