LOCUS       NZ_LFBV01000007        21317 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces uncialis strain DCA2648 scaffold7, whole genome shotgun
            sequence.
ACCESSION   NZ_LFBV01000007
VERSION     NZ_LFBV01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces uncialis
  ORGANISM  Streptomyces uncialis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 445914)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Cloning and characterization of the uncialamcin biosynthetic gene
            cluster
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 445914)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33410, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-MAY-2015
            Assembly Method                   :: CLC Genomics Workbench v. 8.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905345.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:03:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,456
            CDSs (total)                      :: 7,371
            Genes (coding)                    :: 7,214
            CDSs (with protein)               :: 7,214
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 5 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 42 of 157
            Pseudo Genes (incomplete)         :: 143 of 157
            Pseudo Genes (internal stop)      :: 7 of 157
            Pseudo Genes (multiple problems)  :: 33 of 157
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:56:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 411512
            Orig. end                         :: 432829
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LFBV01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21317
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21317
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21317
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11317](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11317
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(556..575)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.43"
                     /tool="antismash"
     misc_feature    1166..1178
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     misc_feature    complement(1750..1770)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.76"
                     /tool="antismash"
     gene            1819..2928
                     /locus_tag="AB852_RS26355"
                     /old_locus_tag="AB852_25950"
     CDS             1819..2928
                     /NRPS_PKS="Domain: NAD_binding_4 (5-250). E-value: 7.2e-40.
                     Score: 128.6. Matches aSDomain:
                     nrpspksdomains_AB852_RS26355_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019605.4"
                     /locus_tag="AB852_RS26355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_25950"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_073792681.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 4e-39, bitscore:
                     128.6, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.9e-13, bitscore:
                     43.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERHLITGATGLVGGMLTLDLLEHYPDAELVCLVRPRGARPAQER
                     LDAALRDAATAYRREAALKRAGQRCRAVSGDLTLPLCGTSGAQVGPVSHVWHSAASLAF
                     EDEAKDAIMQCNVEGTRHVAALAQRLGVGVFNHISTAFVVGDRAGDIPAAPVDPQVRSN
                     NWYERSKVLGERIVSSSGFPTLRILRPSGVIGHDTTFGATTFSGLYGMVKTLLALRLRN
                     RQDFAGQHLRIRADADALVNFVPVNLVTRGAVTLSAADAPSGVYHLSNISQATVADTLS
                     AITERVGMPEPVLVATTDGFTPAEQRLDRAFTFYRPYLSATRHFGLAETLQHTATSMDA
                     PLSRERLVDFVDWYLGTLKRRPSVGGTTG"
     aSDomain        1834..2568
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AB852_RS26355_NAD_binding_4.1"
                     /evalue="7.20E-40"
                     /label="AB852_RS26355_NAD_binding_4.1"
                     /locus_tag="AB852_RS26355"
                     /protein_end="250"
                     /protein_start="5"
                     /score="128.6"
                     /tool="antismash"
                     /translation="ITGATGLVGGMLTLDLLEHYPDAELVCLVRPRGARPAQERLDAAL
                     RDAATAYRREAALKRAGQRCRAVSGDLTLPLCGTSGAQVGPVSHVWHSAASLAFEDEAK
                     DAIMQCNVEGTRHVAALAQRLGVGVFNHISTAFVVGDRAGDIPAAPVDPQVRSNNWYER
                     SKVLGERIVSSSGFPTLRILRPSGVIGHDTTFGATTFSGLYGMVKTLLALRLRNRQDFA
                     GQHLRIRADADALVNFVPVNLVT"
     gene            3128..3331
                     /locus_tag="AB852_RS26360"
                     /old_locus_tag="AB852_25955"
     CDS             3128..3331
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS26360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_25955"
                     /product="hypothetical protein"
                     /protein_id="WP_073792682.1"
                     /transl_table=11
                     /translation="MYAPANRYHGLDGTQMGLIATLTGASYDTVRAAHKADLAAWSREQ
                     QLRDHPDLAVLDADLDRIRHRI"
     gene            complement(3639..4127)
                     /locus_tag="AB852_RS26365"
                     /old_locus_tag="AB852_25960"
     CDS             complement(3639..4127)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_25960"
                     /product="hypothetical protein"
                     /protein_id="WP_073792683.1"
                     /transl_table=11
                     /translation="MLGGAGAVMCAMMAIGAVWTSVGPVGAAAGIGPADGVFTVSRCYA
                     TETNRRCEGSFAPADGTEHRNGVELGSPREPYTGGEQVEVRLAEATAYERSAVTVAFTI
                     ALALLLAGLYGATAAWLGKSARRGRFAGLGLYAAVMAVTSSAALSLLLVTGLLDWLLT"
     gene            complement(4750..5043)
                     /locus_tag="AB852_RS26370"
                     /old_locus_tag="AB852_25965"
     CDS             complement(4750..5043)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS26370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_25965"
                     /product="hypothetical protein"
                     /protein_id="WP_073792684.1"
                     /transl_table=11
                     /translation="MLDPEVEMPIESDTTAYVLWRALGEAVATHPLPPRPVREDTAVAL
                     LSVQDTSDVLLRTRVPIPGTGRARRTSRSGWHHSCHGWPRPSGDWTVSRRCS"
     misc_feature    complement(5121..5134)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.61"
                     /tool="antismash"
     gene            5696..6079
                     /locus_tag="AB852_RS26375"
                     /old_locus_tag="AB852_25970"
     CDS             5696..6079
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453539.1"
                     /locus_tag="AB852_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_25970"
                     /product="VOC family protein"
                     /protein_id="WP_073792685.1"
                     /transl_table=11
                     /translation="MLNEIMYVTIYVTDQDRALEFYTEGLGLEKQLDFPGPDGRFLTVG
                     VPDSPVQIILWSHAPAAGQPGGTGAPGPLILESKDLRKDFEIMRRRGVVFEEPEPVDYP
                     FGVRIEAVDPDGNRVSLRQQRKS"
     gene            6076..6951
                     /locus_tag="AB852_RS26380"
                     /old_locus_tag="AB852_25975"
     CDS             6076..6951
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453541.1"
                     /locus_tag="AB852_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_25975"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_073792686.1"
                     /transl_table=11
                     /translation="MTAHPSALVAEAFEAQRDRLRAVAYRVLGSHADAEDVVQEAWMRL
                     VRQDAATIGNLAGWLTTVVGRISLDLLRSRRAHPEIAYEQEFTNLVVIPDEDPAPDEQA
                     ALADSVGLALLVVLDSLTPSERLAFVLHDMFAVPFHEIGRILGKSTAATKMVASRARRK
                     VHATNRPAGSGREHREVVQAFGAAARSGDFEALLRVLDPNVELTVDTSDGMVVTLGATK
                     VASGARMFSGEVTRHRPVLVNGIPGHMSWHPDGTPLSLIAFAVTEGRITGIHIVVDPAK
                     LASIHLPAET"
     gene            complement(7148..7522)
                     /locus_tag="AB852_RS26385"
                     /old_locus_tag="AB852_25980"
     CDS             complement(7148..7522)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS26385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_25980"
                     /product="hypothetical protein"
                     /protein_id="WP_073792687.1"
                     /transl_table=11
                     /translation="MVLAEDVGGEPDDGAGDALGSVRARLFPGAQGAEEDASEGIEGEG
                     VRARRVDVRVGQGGDVHQERGHPRFGSGEGGGGFEVAGLHLQQLRATALRQALDAHYWQ
                     LRLFGLAELQVGIRSVSLHG"
     misc_feature    complement(7184..7186)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7854..8504
                     /locus_tag="AB852_RS26390"
                     /old_locus_tag="AB852_25985"
     CDS             7854..8504
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049509.1"
                     /locus_tag="AB852_RS26390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_25985"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_245876927.1"
                     /transl_table=11
                     /translation="MTEEPERPAAYREPRQARSAATLARVLRAAEEIATTDGLEDLTMA
                     GVAARAGVAVGTIYRRFDDKEQLITALSERMLEHREEYVAQRQRPAEPSLSGVIDAYAQ
                     ALLQSFADSSGLFQELLRAQGDRSLDRGARTITALHHLLLEAASPYTGQIRRSQPQKAL
                     DTAARAVLGACYHDAVRPDPATGETARRRYAAELTDMAIAYLLTLDGHRSTHT"
     gene            8938..9447
                     /locus_tag="AB852_RS26400"
                     /old_locus_tag="AB852_25995"
     CDS             8938..9447
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS26400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_25995"
                     /product="hypothetical protein"
                     /protein_id="WP_245876928.1"
                     /transl_table=11
                     /translation="MLRLPDQVAGEWEIPRVPLRYDRAVLAAGVVREKLRTTLTATGRG
                     YDVVAHQQAVMPEQFLPPPATEPDRDDDQEPEEAEPREAVDLTAVRALKKSRTDVEALD
                     LTAEQLRHIQKAYERARDQARERAAQYVGQGDADEPSRPVRAGDQQAQAHRPQQPGPHR
                     GPGAGC"
     gene            10001..11317
                     /locus_tag="AB852_RS39935"
                     /old_locus_tag="AB852_26000"
     CDS             10001..11317
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="AB852_RS39935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26000"
                     /product="hypothetical protein"
                     /protein_id="WP_073792689.1"
                     /sec_met_domain="T1TS (E-value: 9.5e-61, bitscore: 200.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLAVPRLRLDLPSGLHPHEDRTQQHTQAWVQEMGMIANSPKVRE
                     VCDSFLLGRLAARVCPHASVGRLYVLADWTSAYFVLDDVLDDTVEARDPEVATEIADQF
                     IAPFLGTAPRTGRHRAGDVLAVPRIREGLADLWARTRPGMTAAWTNRLVHDMTDYLYSH
                     VRQSEINSSETPFDEDAYCAHRLLTSAMYVSADLIEVATARPVPEHLIRNPDIATIREA
                     ASHVVAWVNDLYSAPEEIRLNDLCNYVVVLTSKLDVSLQEAADLVAQRVDVQVGRFLAA
                     ESRAEAVLYPHLQPDDRQALTEMVEGLKTWMTGNALWAEETARYTDRATRRPAPCSTSP
                     HSSDDPGSNRGTGPAQNPRRPCPAPPRMPHDGQRVTGQCRSTPARAKPQAPRAHRVEPA
                     GSRVPPPRIRHQAPPAATGPAHPASPPHPPHRRPESGQL"
     misc_feature    10202..10204
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11314..12660
                     /locus_tag="AB852_RS26410"
                     /old_locus_tag="AB852_26005"
     CDS             11314..12660
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560295.1"
                     /locus_tag="AB852_RS26410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26005"
                     /product="cytochrome P450"
                     /protein_id="WP_073792690.1"
                     /sec_met_domain="p450 (E-value: 1.7e-72, bitscore: 239.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDVPISQAPGALPLLGHLLPLVRDPLKFLTSLPARGDLVHIRI
                     GPKKALLVCDPGLTRHVLVNDRTFDKGGPAFDQGREVLGNGLPLCPHTDHRRQRRLVQP
                     AFHPARLPAYARLMTEQTDTATGSWTDGQTIDAYTEMQNIVAQGLVATMFADTLNPTAI
                     TEVLEDLGAITDGIFRRMITPPRLNTLPTPGNRRYYQARSRLRRTMVRATADRRSAATG
                     HDDLLSVLLGSPDPPEDGHDQNLSDAEIIDQLMAFFFAGIETAAATLAWALHALAQHPH
                     IEEQLHAEADSVLAGAAATLDDVPRLEYTRRVLMESLRRYPPAWLVSRTTTTDTHLGTH
                     PVRAGTAVFYSPYLIHHRTDQYDNPEQFDPDRWSSSRHLNPPDGSFIPFGGGARKCVGD
                     QFGITEAVIILATIAARWRLEPLPGRPVRPALALTLSPQRLHMRLRPRT"
     gene            complement(12978..13424)
                     /locus_tag="AB852_RS26415"
                     /old_locus_tag="AB852_26010"
     CDS             complement(12978..13424)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670177.1"
                     /locus_tag="AB852_RS26415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26010"
                     /product="hypothetical protein"
                     /protein_id="WP_073792691.1"
                     /transl_table=11
                     /translation="MPDTTVAESLTPMTPHAVTAAFDHLRAVQAGALEVAAALAAAEPR
                     TSAILVDVATRIVAPVTALPDPDMDAACADAFALDALGGVFLSALRTWEQAGPDAAEGI
                     ARTVIRFTADVLTEDHEDIDDILRQALDAHPTLAGAHPIRPGIV"
     misc_feature    13537..13552
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    14180..14195
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.25"
                     /tool="antismash"
     gene            complement(14542..14991)
                     /locus_tag="AB852_RS26420"
                     /old_locus_tag="AB852_26015"
     CDS             complement(14542..14991)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109734.1"
                     /locus_tag="AB852_RS26420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26015"
                     /product="hypothetical protein"
                     /protein_id="WP_073792692.1"
                     /transl_table=11
                     /translation="MPENTVTTPLAPMELGDVVDAFAYIRALQSGEIDTAGAVANDTGP
                     EMRRLLLDVAARIFIPITAVDDCDGEPCAHSFLAAALGRLLLEVLCHADGACLAFPPGI
                     AQTIIRFTDNILTEDHGDVADVLRQLEAAGMKQAVEADPVHRTTA"
     misc_feature    15063..15076
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.57"
                     /tool="antismash"
     misc_feature    15185..15198
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.19"
                     /tool="antismash"
     gene            15252..15722
                     /locus_tag="AB852_RS26425"
                     /old_locus_tag="AB852_26020"
     CDS             15252..15722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015449443.1"
                     /locus_tag="AB852_RS26425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26020"
                     /product="hypothetical protein"
                     /protein_id="WP_073792693.1"
                     /transl_table=11
                     /translation="MTTQRLPFPVPDERAHYFVTCYADMHDLVEDLVVPDGVPEAAATV
                     LRTARELLRQSYYCYEFSTVAVMHSLIAVEIVLRDRIPDAGKKPLHQLIKQGADAGLLT
                     ARQAEYLDDGRRIRNRLVHGHTAHAVMPPAMSVPMVTTSFAIVSELCAAPTG"
     gene            16106..16897
                     /locus_tag="AB852_RS26430"
                     /old_locus_tag="AB852_26025"
     CDS             16106..16897
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025186.4"
                     /locus_tag="AB852_RS26430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26025"
                     /product="replication-relaxation family protein"
                     /protein_id="WP_073792694.1"
                     /transl_table=11
                     /translation="MLGCVRVATVRQLAQVSTAEGRDGRSYVRRAMKRLAELGLADTNG
                     KAGRHPIWNLTVAGQKALADGNELPPRPKAGTGAKAVAAGFGPHGIAVADTILAFGCRD
                     HLTGWQVEVNHAIKETGLSFNTDAVLAWPTKTSEVRLFELDNGTMPQARLAREVWDYER
                     YAGHRVWEGARGTIGGTFPFWQRHRYTRSETFPRLHVVLAGKAEHLLDNRPQALAADVR
                     GITIEVWVNTLPRLKRREPWYEIGTDDPDRRRQRYPETLGR"
     gene            complement(16873..18420)
                     /locus_tag="AB852_RS26435"
     CDS             complement(16873..18420)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005322234.1"
                     /locus_tag="AB852_RS26435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_178391121.1"
                     /transl_table=11
                     /translation="MAVFPPASGRAAAMPRLLDLDGRGELRAAHVRLVAQALGKSERTV
                     WRWLAAAREDHRLARVESSHFTVTTEVRRLLALWGGNASRVHAELVQRAAGDPDAPAVP
                     SLSTLHRAIRRDLTRGERAGLKSGEAARRAHDVFGQRPATHRNAAWEGDHKHVPVEVDV
                     EGELATPWVTWFIDCATKAITGVAVTAHAPSRDAVLASLRIAITRSEPFGPVGGLPGEI
                     RVDRGKEFLCQAVSAAMGALAVPVTDLPAYTPHLKGTIEALNDAVEEMFLVSLPRYTGR
                     QRLTGGALADPDAPPLTYEAFVGLLLDWVTWWNTRHHPSALNGKTPLQTWQADATPLTD
                     VAAGQLATFALEDDGRTYTISTSGVRWRRRDYLAPWMNGRTGTKVSVRHLPHHDDTIEV
                     FDAATGRHLGSAFLAAAASREQIRSGQAAAAAMSMSWFLSRLLCLMLGSPPLVVVSTSP
                     WYAGSGAQCVPGPGSSRAVARGLRRPSRPPGPDAGQPPPQRGRARRCAQPQRPSVSG"
     misc_feature    complement(18856..18872)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.89"
                     /tool="antismash"
     gene            19039..20058
                     /locus_tag="AB852_RS26440"
                     /old_locus_tag="AB852_26035"
     CDS             19039..20058
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042538.2"
                     /locus_tag="AB852_RS26440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26035"
                     /product="ABC-three component system protein"
                     /protein_id="WP_143201285.1"
                     /transl_table=11
                     /translation="MYLQYIYDADDWEDFTVEWVRQFGSWSGRPYVRVQRMGGAGDRGA
                     DVAACLSAQGTAGEWHCYQCKHYVKPLGQSDAFPEMVKIFVAKILGTYELPTRYVFVAP
                     KIGTGLERLLLNPPQLKDEFFAAWDDKNSKLGTKPKLTPEMRTAVGALAQATDFSMFEA
                     RNLEEILKLHAATPHHVRRFPQPLKQRPAADPAPPDQAPHEAVYVRKLLDAYNAKHGLA
                     LETLQQARDHAKVSGHLFRQRAAFFHAESLWRFAQESVPEATYTAIETDLYDAVIEIED
                     RDHASGYARLEAVLDAAVAHTPNPANILAPVVKVIDLKGMCHRLANDDRLTWCKEEAL"
     gene            20055..20537
                     /locus_tag="AB852_RS26445"
                     /old_locus_tag="AB852_26040"
     CDS             20055..20537
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042474.2"
                     /locus_tag="AB852_RS26445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_26040"
                     /product="ABC-three component system middle component 2"
                     /protein_id="WP_107499353.1"
                     /transl_table=11
                     /translation="MTPLNSPVEAGMRALVLLSEAFPRRLDVAQLVYLDHAMLHSGDLD
                     HGPASLHPDLPAGPGELGLRRHLIEQGLMVLLRAGLADMTTTDDGFMYGATDEAAGFLS
                     ALESPYVGQLIERADWLTSTYMHEGTDVREGMKQITQRWSGRFQVSTADLGEEDVL"
     misc_feature    21221..21239
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.35"
                     /tool="antismash"
     misc_feature    21222..21238
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.09"
                     /tool="antismash"
ORIGIN
        1 accgccaccg tcggcctgac cgccgacagc cgcctcggcg gcgacaccca cggccactac
       61 gccgccaccg tcgaagccac cggcgacaac cagaccatcc gcaccaccgc cgccgtcgaa
      121 ctcgaagccg agtcctacga catcaccttc aaacacatcg gacgcgacgg aaaacccagc
      181 aagcacttcg aatcatccct cagctccctg accgacggtc cggggatgat cctgtccggg
      241 acacccgaga ccgtccagcg tctgcccaag ggcgagtacg cgctcgacgc cagcgccccc
      301 atcgatcccg ccgccgaccc gaccggccgg accaagggct tcgacctcgt gatccagccc
      361 aagctggccg tcgacaggac gatgacggtc accgtcgacg cccgcaaggc caaacccgcg
      421 aagctgacgc tgagcgatgt gaaggccaag ttcaccggcg ggcagatgga gtacgtgcaa
      481 acagcgcccg accggcagga cacccgtggc gtgcgcttcc cgatgcgctc acccggcggg
      541 ctgaacatcg cccacctcgg gccgcaggtc accgacggaa ccctgcacca gcagtggcac
      601 gccaactgga tcaaggacgc tcgcagtgag taccacggca cctccggcgg tccggtgaca
      661 cggatcgcca ccgggtacaa gcgcaccttc aatgccgcgg agttcgccga ggtgagggtg
      721 ggactcgctg cctcggccaa ggacaaacag ggcctgctgc aagcgtacgg ggtcctcccc
      781 agcaccctct tcggattcgg gggagccccc gccacgcgga agatacccgc cgcgcgcacg
      841 ctgcatctgt ccaccggcga ccgggccaag tggcagctcg cgctgaccca gaccccggcg
      901 ggcaccccgg cagacgatcc cgagcccgag gtgcgccact acagcgaacc ggcgtcctac
      961 cccaagggca aggtccaccg ggagaccctc ggtaccgctg ccgtcgcccc gaaggccggc
     1021 agcgcctcgg gattctggcg ctacggcgag atgctgtacc ccgatgtgcc gatgttcgcc
     1081 gacggccagg gcaacaccgg aacatcccag ttcgcctcgg ccacgaccac gctgtaccgc
     1141 aacggtacga aggtcgccga gaacagtgac ccggtcaccg gccaggaggg gctccagatc
     1201 ggccgcgaag ggggagactt cctgctcacc acctcggtcc ggcgaagtcc ctcgaccgct
     1261 ctggtgagca gccggatcga ctccgcatgg gccttccgcg cgaacgcggc gcccacggac
     1321 ggcgagctcc ggctgccggt ttccaccgta cgtttcacgg gtgtgcggtc cgggctcacc
     1381 ggcaccgccc cggcgggcgt cggccagacc atcccgctgg aggtgcacgg cgcggccaag
     1441 gacaaggtca agtcgctgac cgcgcgcgtc tcctacgacg gcggcaagac ctggaagaag
     1501 ctgagggtca ccaagaacaa ggtgaccctc aagaacccgg ccaagggcaa gggcatcacc
     1561 ctgcgcgccc aggtcgtcga caagcagggc ggctcccaca aggtgaccgt gtacaacgcc
     1621 ttcttcggca agtagacgaa cgagccgcgc gcggcaccgc gagggcggtc cgccggtaca
     1681 tcccgtaccg gcggaccgcc cttccccgcg ccaggggacc gcctgtgagc gcacgcgata
     1741 tcgtcatctt tgtagtcttt agcccgataa gggcgatgat cgcgtcgtgc cgggcgcaga
     1801 tgaagagaga cgggcctgat ggagcgacac ctgatcaccg gggcaaccgg gctcgtcggg
     1861 gggatgctga ccctggacct gctcgaacac tatcccgacg ccgagttggt gtgcctggtg
     1921 cgaccgcgcg gcgcaaggcc cgcccaggag cgcctggatg ccgcgctccg cgacgcggcc
     1981 acggcatacc ggcgcgaggc cgcgctcaaa cgcgccgggc agcgctgtcg ggccgtgtcc
     2041 ggggatctga ctctgccgct gtgcggcacc agcggcgcgc aggtcggccc cgtctcccac
     2101 gtctggcact ccgccgcctc cctcgccttc gaggacgagg ccaaggacgc gatcatgcag
     2161 tgcaacgtgg aaggcacccg ccacgtggcc gccctggccc agcggctggg agtgggcgtg
     2221 ttcaaccaca tcagcaccgc cttcgtggtg ggtgaccgcg ctggggacat ccccgccgcg
     2281 ccggtggacc cgcaggtgcg ctccaacaat tggtacgagc gctccaaggt cctgggtgag
     2341 cggatcgtct cctccagcgg gttccccacc ctgcggatcc tgcgtcccag cggtgtgatc
     2401 ggccacgaca ccaccttcgg tgccaccacc ttcagcggcc tgtacggcat ggtcaaaacc
     2461 ctgctggcac tgcggctccg caaccgccag gacttcgcag ggcagcacct gcggatcagg
     2521 gcggacgcgg acgcactggt caacttcgtc ccggtcaacc tcgtcacacg cggtgccgtc
     2581 accctcagcg ccgcagacgc cccgtcaggc gtctaccacc tgtccaacat ctcccaggcc
     2641 acagtggccg acaccctgtc ggccatcacc gaacgagtgg gcatgcccga accggtactc
     2701 gtcgccacca ccgacgggtt cacccccgcc gagcagcgac tggaccgtgc gttcaccttc
     2761 taccggccct acctgagtgc caccaggcac ttcgggctgg ccgagaccct ccagcacacc
     2821 gcaacctcca tggacgctcc cctctcgcgc gagcggctgg tcgatttcgt cgactggtac
     2881 ctgggaaccc tcaaacggcg gccctccgtg ggcggcacca ccggctgatt cccccaccat
     2941 tgagctggcc gaagcggaca tcgcgccgct cgccgcgttc gccgacgccc tcgaccaagc
     3001 agcccggcgt gacccgggaa cgacggctgg gggtccctgc tgggaggacc aggacacccc
     3061 gttccggcgc cggctccacg caaagctcgc cgcggccgga ttcgagtgcg cggccgatgc
     3121 cgtcatcatg tacgcgcccg ccaaccggta ccacggcctc gacggcaccc agatgggcct
     3181 gatcgccacc ctcaccggcg ccagctacga caccgtacgg gccgcccaca aggccgacct
     3241 cgccgcgtgg tcccgcgaac agcagctccg cgaccacccc gacctcgccg tcctcgacgc
     3301 ggacctggac cgcatccggc accgcatctg accacgcgcc gggtgctcgg tgcgcatccg
     3361 tatgcgcgcg gagcaccggc gcgtgccgag ctgagatcgg tcaacccccg cccgtcgccg
     3421 tcgccgtcgc cgtcgtcgtt gcgcggcgca gctgccgcgc ggccggaatg ccgttctctc
     3481 ggcgggggag gaggtgatca ggatgtcgtt gccgcgccgg cggacgccgg gtgctgcctc
     3541 ctcttggtgg tgtggaccgc gatgccgaac cacttcgtgc ccggttcaga cggcctcgtc
     3601 cgaactcgcc gccgtcgcga cctggtgggc ggggatggtc aggtgaggag ccagtcgagg
     3661 aggccggtca cgaggagaag agacaacgcg gcggagcttg tgacggccat gacggcggcg
     3721 tagaggccga ggcccgcgaa tctgccgcgc cgggcggact tgccgagcca ggcggccgtc
     3781 gcgccgtaca ggccggccag gagcagggcc agcgcgatgg tgaaagctac ggtgacggcg
     3841 gagcgttcgt aggcggtggc ttcggccagc cggacctcca cctgttctcc tccggtgtac
     3901 ggctcccggg gcgaacccaa ctccaccccg tttcggtgtt ccgtgccgtc ggcgggggcg
     3961 aaggagccct cgcacctgcg gttcgtttcg gtggcgtagc agcgtgacac ggtgaacacg
     4021 ccgtcggccg gcccgatacc ggccgccgcg ccgaccgggc cgacactcgt ccacaccgct
     4081 ccgatcgcca tcatcgcgca catcaccgca cccgcacccc ccagcaccct ccacctccat
     4141 acccgtgccc gggtccgtcc tgcggtccga atccgcggta tccgcttcat cccgccccac
     4201 ctccggcgtc tggagtcccc gccacccccg gacgccaaac cccgcacgca cacgaccagg
     4261 agccgaaaag caccgccgcg gctggttccg tcggcggccc tgaccggaaa ccctcaccgg
     4321 cggccgggga gccatcggac cgcgcagcgg gacggacccc gaagtccccg tgccaccgcg
     4381 cggaccgatt ccgttcttga gcgccggagg ctcgcatggc acgtcagcgg tgagtgaggg
     4441 acatcccagc cggtgcccgc agtgacgatg ccgagtaccc gcccgtgccg tgcccggcga
     4501 cgtcgcgcac tccccggtcc gggtccccgg tggcaggggc gggtcgacgg cgtaccggct
     4561 cagtccctgc ttgggatctg ccagatgctg cggcacgtcc ggtgcctgcg gagtgcccgc
     4621 acgctccggc gagatggtcg ccgtagacgc cggacccggt cgccgccgct tgtcgggcca
     4681 gggttacgag ccccgacgcg agccgttcgt ccagcgggat cacaccgtcc gcccatccga
     4741 ccgacaccgt catgaacagc ggcgcgagac cgtccagtcc ccggaaggtc tcggccagcc
     4801 gtggcaggag tggtgccagc cgctgcgcga ggtgcgcctc gctcggccgg ttccagggat
     4861 cgggacccgg gtccggagca ggacgtcgct ggtgtcctgg acggacagga gcgcgactgc
     4921 ggtgtcctcc cgcaccggcc gtggggggag cgggtgggtg gcgaccgcct cgcccagggc
     4981 ccgccacagc acatacgccg tggtgtccga ctcgatcggc atctccacct cggggtccag
     5041 cacgggcgca ctctcctgaa gtcgcagggg gcttctccgg cagcgtcccc gacccggcgg
     5101 ccccgcacag gccccggcaa cgaacctgtg ttcttcctcc cgcccagcgg gcaacaacct
     5161 tctccacggc tccatccggc gggcccgcgc gagcggtggc gacgcgcgag accgcgccgg
     5221 gcagcccgga gcccggctac cgccgcggcg gtgcccggcc ttgccgtccg gccccgccca
     5281 ccaacctctg cgcccggtcc ggcggccccc ggcaggtccc ggcgagctgg ctgcgtcccg
     5341 gcctccgggc ggggacgcgg gggagcggga agagctgcgc accaactact gggcgtgctc
     5401 accggccttg aaggatcttg ctgctgggct tgaccatcag caagatccct tcaccggacc
     5461 ggcggtccgc cgaacacgaa ccctgtctcg gcgacggggt cgcacagaga acctgtccgg
     5521 ccccagggac cgcagagcga gacgaagccc gcccgatgct tctcaggcat cagcggtgag
     5581 gcgtgttccg tttccgcccc cgcggaccgg tcttgttacc ttctcccgtc ggcactcgtc
     5641 atgagagcga cgaccgcaca cgaacggtcg catcgacgag tgaatcgaga gcaggatgct
     5701 gaacgagatc atgtacgtga cgatctacgt cacggatcag gaccgcgcgc tggagttcta
     5761 caccgaggga ctcggtctgg agaagcagct cgacttcccc gggcccgacg gacgtttcct
     5821 taccgtcggg gttcccgaca gcccggtgca gatcatcctg tggtcccacg cgccggccgc
     5881 aggacagccg ggaggcacgg gcgcgcccgg tccgctgatc ctcgaatcca aggacctgcg
     5941 gaaggacttc gagatcatgc gccgacgcgg cgtcgtcttc gaagagcccg aacccgtgga
     6001 ctatccgttc ggggtccgca tcgaggcggt ggatccggac ggcaaccggg tctcgctccg
     6061 tcagcagcgg aagtcgtgac tgcccacccg tccgctctcg tggctgaggc gttcgaagcc
     6121 cagcgcgacc ggctgcgcgc tgtcgcgtac cgggtgctgg gctcgcacgc cgacgccgag
     6181 gacgtggtcc aggaagcctg gatgcgcctc gtccgtcagg acgcggcgac catcggcaac
     6241 ctggcgggct ggctgaccac ggtggtcggc cgaatcagcc tggacctcct gagatcccgc
     6301 cgagcccacc ccgaaatcgc ctatgagcag gagttcacga acctcgtggt gatacccgac
     6361 gaggaccccg cgccggacga acaggcggcg ctggccgatt cggtcggcct cgccctgctc
     6421 gtcgtgctcg actcgctcac cccgagcgag cgtctggcgt tcgtcctgca cgacatgttc
     6481 gcagtcccgt tccacgaaat cggccggatc cttggcaagt ccaccgccgc caccaagatg
     6541 gtcgccagcc gcgcccgccg caaggtccac gccacgaacc gaccggcggg ctccggccgc
     6601 gagcaccgag aggtcgtcca ggcattcggc gccgccgccc gcagcggcga cttcgaagca
     6661 ctcttgcgtg tcctcgaccc gaacgtggag ctgaccgtcg acacatccga cggcatggtc
     6721 gtcaccctcg gcgccaccaa ggtcgcctcc ggggcccgca tgttctccgg cgaggtcacc
     6781 cgccatcggc ccgtgctggt caacggcatc cccggccaca tgtcctggca ccccgacgga
     6841 acccccctct ccctcatcgc cttcgccgtc accgaaggac ggatcaccgg catacacatc
     6901 gtcgtcgacc ctgccaaact ggcctccatc catctgcccg ccgagacctg agccggtgtc
     6961 gagcaccccg cactccgaca ggacggtgtc cggtgcgatg gcgagaccac gctccggcgt
     7021 cgagtccaca cgccatccgc cgtggccgga gccgcgcggg ctgtgaactg gcgttatgcc
     7081 tccgagacag tacgctcgtc cgcagcggac gacgggagac aggatcgtgg gaccgaagtg
     7141 ggctggccta accatgcaga gaaacactcc ggatcccgac ctgtaattcc gcaagtccga
     7201 atagccgcag ttgccagtag tgtgcgtcga gggcctggcg gagggcggtg gctcggagct
     7261 gctggaggtg caggccggcg acctcgaagc cgccgccgcc ctcgccactg ccgaaccgcg
     7321 gatgcccgcg ctcctggtga acgtcgccac cctgcccgac ccggacatcg acgcggcgtg
     7381 cgcggacgcc ttcgccctcg atgccctcgg aggcgtcttc ctcagcgccc tgcgcacctg
     7441 ggaacaggcg ggcccggacg ctgccgaggg catcgcccgc accgtcatcc ggttcaccgc
     7501 cgacatcctc agcgaggacc acgaggacat cgacgaccgt cggtcctgcc ggtccgacgg
     7561 cggtgatccg gccggggccg agccgctcgc gagggacgcc aggcccggcc caacgccagc
     7621 ttccgccgcc agcttccgca ggctgctcta cgagtcgcct cgacggtcat gggcagggcg
     7681 gggagatcag caggtcagtg ccctgttcaa gggggttcgg ttgcgccgac tacttctctc
     7741 agggaccccc aggagcgttg aggagcccag tgaagtcgac gggggcgggg gcggaaagtg
     7801 tcggggaaac agtgcagtgc ccagtggagg tggtacggcg ggccatgtgg gacatgaccg
     7861 aggagccgga gcgtccagcg gcctaccggg aaccccggca ggcccgcagc gccgcgaccc
     7921 tggcccgcgt cctgcgggcg gccgaggaga tcgccaccac cgacggcctg gaggacctga
     7981 caatggccgg cgtcgccgca cgcgccggcg tcgccgtcgg cacgatctac cgccgcttcg
     8041 acgacaagga acagctgatc accgccctgt ccgagcgaat gctcgaacac cgcgaggaat
     8101 acgtggccca gcgacaacga cccgccgagc cctcactctc aggcgtcatc gacgcctacg
     8161 cacaggccct gctgcaatcc ttcgccgaca gcagcggcct cttccaggag ctgctgcgcg
     8221 cacaggggga caggtcgctg gaccgcgggg cccgcaccat caccgcactc caccacctcc
     8281 tcctcgaagc ggcatccccg tacaccggcc agatccgccg ctcccagccg cagaaggcac
     8341 tcgacaccgc tgcccgcgcc gtcctcggcg cctgctacca cgacgccgta cgccccgacc
     8401 ccgccaccgg agaaacggcc agacgccgct acgccgccga actcaccgac atggcgatcg
     8461 cctacctcct caccctcgac ggacaccgct ccacccacac ctgagccgag cacactgccg
     8521 gacagttctg gcccgggtcc cggccgtggt cgacgtcgcc ctggccgccg ccagcgtggc
     8581 agcggtgctg ttcgtgatga acaaggacgg caccttccaa cgccgtcacc tcctcgccga
     8641 agcgcgacgc cacctcgccc tcgtcctgag gggccgcccc cgtgaacccg gcctcgacga
     8701 ccaggtcgtg gacgccgcca tcgccacgca ctgcctcgac atcaccgact ccgggacgct
     8761 gcacagcggc accatggccc accgcctcta caccacccgc tggaccgagg ccgacctcaa
     8821 gcccgcccgc cgacggccgg ccatcccgga tgaggaccac cggctcccgc cgacacgggc
     8881 acgccgccca ccctccggct cccggacgag gccccgtccg acacaggtgc cccgcacgtg
     8941 ctccggctcc ccgaccaggt ggcgggggag tgggagatcc ccagggtccc gctgcgctac
     9001 gaccgggccg tcctcgccgc cggggtggtc cgcgagaaac tccgcaccac cctcaccgcc
     9061 accgggcggg ggtacgacgt ggtcgcgcac cagcaggccg tcatgccgga acagttcctc
     9121 ccgcccccgg ccaccgagcc cgaccgcgac gacgaccagg agccggagga ggccgaaccc
     9181 cgggaagcgg tcgacctgac cgcggtgcgc gctctgaaga agtcacgcac cgatgtcgaa
     9241 gccctcgacc tcaccgccga acagctgcgc catatccaga aggcgtacga gcgggcgagg
     9301 gatcaggccc gagagcgggc agcccagtac gtcggtcagg gggatgccga cgagccctcg
     9361 cggccggtgc gcgcgggtga ccagcaggcg caggcgcacc gcccgcagca gcccggaccg
     9421 caccgcggcc cgggggccgg ctgctgagcg gaccccggcg agtggagccc accggccggt
     9481 cggtgccgcg ggggtccact ggacggagtg gtctccaccg gcaggcgggg gccgtcgtgc
     9541 gggagcgtcc ggcatcgccg gacgatgccg gacactccgg ttcccgtgca cccggcgcgg
     9601 accggatgca cgggaaccgt cccccgcgat gcacggcatc gtcaccggcg atgccgtgca
     9661 cgccgggccg gtgcgcggcc aaatgagatg atctcttagc cgcctcgcac cataccgaag
     9721 cctctcccac cagcaacgac gggcagcaca cctcgccccg ttcgcatccg cgtgcgatcc
     9781 ccgagaacca tccgcctcgc cccccgccct cagggtgctt ttcctagcgg gccttcgtct
     9841 ggcccgcccc ctggttcgcc tgccggggat cgttcaacac gttcacgccc ttttggttac
     9901 cgagaccttc ccttcctggg gtgggactgg ctctcttgaa aggaaaggaa ccggcgggcc
     9961 gctgccccgc cactgtcagg acgaggacca gggagtgctc atggatctcg cagtccctcg
    10021 gctccgcctc gatctgccgt ccgggctcca cccccacgaa gaccgcaccc agcagcacac
    10081 ccaggcgtgg gtacaggaaa tgggcatgat cgccaacagc ccgaaagtgc gggaggtctg
    10141 cgactcgttc ctgctcggaa ggctggccgc ccgggtctgt ccccacgcct ccgtcggccg
    10201 tttatacgtc ctggcggact ggacgagcgc ctacttcgtc ctggacgacg tcctggacga
    10261 cacggtggag gcccgcgacc cggaggtggc caccgagatc gccgaccagt tcatcgctcc
    10321 cttcctcggc accgctccgc gaaccgggcg ccaccgggcg ggcgacgtcc tcgcggtgcc
    10381 gaggatccgg gaaggactgg ccgacctgtg ggcccgcacc cggccgggca tgaccgccgc
    10441 gtggaccaac cgcctcgtcc acgacatgac cgactacctc tactcgcacg tccgccagtc
    10501 ggagatcaac tcctccgaaa cccccttcga cgaggacgcg tactgcgccc accggctcct
    10561 gaccagtgcc atgtacgtct ccgccgacct catcgaggtc gccaccgcca ggccggtgcc
    10621 cgaacacctg atccgcaacc cggacatcgc gaccatccgc gaagccgcct cccacgtcgt
    10681 ggcctgggtc aacgacctgt actccgcgcc cgaggagatc cgcctcaacg acctctgcaa
    10741 ctatgtcgtg gtcctgacca gcaaactcga cgtctccctg caggaagccg ccgatctcgt
    10801 cgcccagcgg gtcgacgtcc aggtcggacg gttcctcgcc gccgagagcc gcgccgaggc
    10861 cgtcctctac ccccacctgc agcccgacga ccgccaagcc ctcaccgaaa tggtcgaagg
    10921 actcaagacc tggatgaccg gcaacgccct ctgggcagag gaaaccgccc gctacaccga
    10981 ccgcgcgacc cggcgaccgg ccccgtgcag cacctcgcca cactcatctg acgaccccgg
    11041 cagcaaccgc ggcacaggcc ccgcacagaa tccccgccgg ccatgcccgg cgccgccgag
    11101 gatgccccat gacggacagc gggtcaccgg gcagtgccgt tccacgcccg cacgcgccaa
    11161 gccccaagca cccagggcgc accgggttga accggcgggg tcgcgggttc cgcctccccg
    11221 gatccggcac caggctccac ccgcagcaac cggccccgcg caccccgcgt ccccgcctca
    11281 tccaccgcac cgccgaccgg agagtggaca gctatgacaa cggacgttcc gatcagccag
    11341 gcaccgggag cgctgcctct cctcggccac ctcctgccac tggtacgcga ccccctgaaa
    11401 ttcctcacct cactgcccgc ccgcggagac ctggtccaca tccgaatcgg ccccaagaag
    11461 gcccttctgg tgtgcgaccc gggactgacc cgccacgtcc tggtcaacga ccgcaccttc
    11521 gacaaaggcg gcccggcatt cgaccagggc agggaagtcc tgggcaacgg cctgcccctc
    11581 tgcccccata ccgaccaccg ccgccagcga cggctggtcc agcccgcctt ccaccctgcc
    11641 cgcctgcccg cgtacgcccg cctgatgacc gaacagaccg acaccgccac cggctcgtgg
    11701 accgacggcc agaccatcga cgcctatacc gagatgcaga acatcgtcgc ccagggcctg
    11761 gtggcaacca tgttcgccga caccctcaac cccaccgcca tcaccgaggt actggaggac
    11821 ctcggcgcca tcacggacgg catcttccgg cgcatgatca caccaccgcg cctgaacacg
    11881 ctccccaccc ccggcaaccg ccgctactac caggcccgat cccgcctgcg ccggaccatg
    11941 gtccgcgcca ccgcagaccg ccgctccgcc gccaccggcc acgacgacct gctgtccgta
    12001 ctcctcggca gccccgatcc ccccgaagac ggccatgacc agaacctttc cgacgccgag
    12061 atcatcgacc agctgatggc cttcttcttc gccggcatcg agaccgcggc cgccaccctg
    12121 gcatgggcac tgcacgcact ggcccagcat ccccacatcg aagaacagct ccacgccgag
    12181 gccgacagcg ttctcgccgg cgccgcagcc acactcgacg acgtgcccag gctggaatac
    12241 acacgccgcg tcctcatgga atccctgcga cgctatccgc cagcctggct cgtcagccgc
    12301 accaccacca ccgacacaca cctcggcacg caccccgtcc gcgccggcac ggccgtcttc
    12361 tacagcccct atctcatcca ccaccgaacc gaccagtacg acaaccccga gcaattcgac
    12421 cccgaccggt ggagcagctc ccgccacctc aacccaccgg acggctcctt catcccgttc
    12481 ggcggaggcg cccgcaagtg cgtcggcgac cagttcggca tcaccgaagc cgtcatcatc
    12541 ctggccacga tcgccgcacg atggcgcctg gaacccctgc ccggccgccc cgtccgcccc
    12601 gccctggccc tcacactcag cccgcaacgg ctgcacatgc gcctcaggcc ccgcacatag
    12661 caccgcccgg gtcccgaacc ctgcacaccc cgcgtcggct tcactcagcc cacagaggac
    12721 gaaggcccac ccgcctgggc ggtgcggcgt gctcggcccg gccaagcacg ccgtcggatc
    12781 atcgctgccc cgacggctcc agcactcaac ggctacacac tcgccccccc aaataggggt
    12841 cacatcaccg tgctggcgca cctgctcagc ctgtgcaacg gctcgcccgg cgcgaccaac
    12901 cccgcaggcc agccagttgt gtgaaccacc cagcgggcct tgacccctcc gcacccggcc
    12961 ggggatgcgc ccgcgttcta cacgatgccg ggccgtatcg gatgtgcacc ggccagtgtg
    13021 ggatgtgcgt cgagggcctg gcggaggatg tcgtcgatgt cctcgtggtc ctcggtgagg
    13081 acgtcggcgg tgaagcggat gacggtgcgg gcgatgccct cggcagcgtc cgggcccgcc
    13141 tgttcccagg tgcgcagggc gctgaggaag acgcctccga gggcatcgag ggcgaaggcg
    13201 tccgcgcacg ccgcgtccat gtccgggtcg ggcagggcgg tgacgggggc gacgatccgg
    13261 gtggcgacgt ccaccaggat cgcggacgtc cgcggttcgg cggcggcgag ggcggcggcg
    13321 acttcgagtg cgccggcctg caccgcgcgg aggtggtcga aggcggccgt caccgcgtga
    13381 ggagtcatcg gagtgagcga ttcggcgacg gtggtgtcag gcacaggggt actcctgtcg
    13441 tcgggctgcc gtgctgatca cgacggcttc ggacagcctc gggcgcaggc cctgtggaca
    13501 gcggccggag atttctcccc cctttccgaa ccggtgcgaa ccgtctggtc aagggtctag
    13561 ccgtcacata ccggaccccc ttgatcagta ccggcccttg gggcgcccgg cccatggctc
    13621 tggtccaccg aaacgaccgg cgtccgaccg gcggccaccc gaggagccgc tggccctgcc
    13681 ggtccgatgg cggtgatccg gcccggggcc gggccgctcg cgacggacac cgagcccgtc
    13741 cccacgtccc tcttccgcag gttgccctac gacttgcctc ggcgtcatgg gcgggacgga
    13801 gaaatcagca ggtcagcgcc ctggtcaaag gggttcggct gcgccgactg cttctctcag
    13861 agacccccag agtaatgaag agcccagcga agtcgacagg agcggggacg gaaaggggcg
    13921 gggagaggcc ggtacggacg gcagcaggct gaaaacggac agacgccagc ttccgcaggt
    13981 cgccttacga gtcgccttac gaatcgcctc gatgtcatgg ggagggcggg gaaatcggca
    14041 ggtcagtgcc ttggccaagg gggttcggct gcgccgacta cttctctcag ggacccccag
    14101 gagcattgag gagcccggtg aagtcgacag gagcgggggt ggaaaggcac gcggggagag
    14161 gccgggacgg ccggtatcca ggctgagaac gaacagacag cgcagtgcgg caagcgatac
    14221 ggagggagcg gccgacaagg gaagaggcga gcaggggagg gagggaaggg atgagcgacg
    14281 agaggagcgg ccgacgggac ggcggcttcc gttcccggat ggaggtgtgg atgccctcgg
    14341 gcccgggtac cggggcatcg ccacggacct ctgaacccgc ctgcctggcg ctgccgtgtg
    14401 ctgcgcccgg ggccgggtgc gcgcacggga tgcgcgcggc gcggtccacg gtgcgcatcg
    14461 tgcgcgcgcc tcccaccggt ggcgcgcgca cgatgcgcac caccggtggg ctcggtgcgc
    14521 cctacacgcc gctggtgcgc tctacgcggt ggtgcggtgc accgggtccg cctccaccgc
    14581 ctgcttcatc cccgcggcct ccagctggcg caggacgtcg gcgacatcgc cgtggtcctc
    14641 ggtgaggatg ttgtcggtga agcggatgat ggtctgggcg atgcccggcg ggaaggccag
    14701 gcaggcgccg tcggcgtggc acaggacctc cagcagcagc cgtccgagcg ccgcggccag
    14761 gaaggagtgc gcgcacggct ccccgtcgca gtcgtccacg gcggtgatgg ggatgaagat
    14821 gcgcgcggcg acatccagga gcagccggcg catctccggg cccgtgtcgt tggcaaccgc
    14881 gccggcggtg tcgatctcgc cggactgcag cgcccggatg taggcgaagg cgtcgacgac
    14941 gtcgcccagc tccatcgggg cgagcggggt ggtgacggtg ttctcgggca tggcagctcc
    15001 ccacgttcgg gccgccctgc tgatcgcggc ggcctcgaag acaccctcga atccgcgccc
    15061 tgtggacaga gtccgagcac cgacggtgag cagccacggc ccggccgcgc cccgcgtttc
    15121 tccttgacca cgtcctttac atgcgacata ccgcccattt caacaggggg gaattgtccg
    15181 tcccggcacg ctgcgcgatg accaggggaa agccgctgcc gcccggggcg cgccgctggg
    15241 agactgcggg gatgaccacg cagcgcctgc cgttcccggt cccggacgaa cgggcccact
    15301 acttcgtcac ctgctacgcc gacatgcacg acctcgttga ggacctggtc gtgcccgacg
    15361 gtgtgcccga ggccgcggcg acggtcctgc gtacggcgcg cgagctgctg cgccagtcgt
    15421 actactgcta cgagttctcc accgtggcgg tcatgcactc cctgatcgcg gtggagatcg
    15481 tgctgcgcga ccggatcccg gacgcgggca agaagccgct gcaccagctc atcaagcagg
    15541 gcgccgacgc gggcctcctc acggcccggc aggcggagta cctcgatgac ggccgtagga
    15601 tccgcaaccg tctggtgcac ggccacaccg cgcacgcggt gatgccgccg gccatgtcgg
    15661 tgccgatggt gacgacctcg ttcgcgatcg tctccgagct ctgcgcggcg cctaccggat
    15721 gatcacggct cggtaacggt gatcagtgat tcgtcacacc gttggctttc gcgacacctc
    15781 tagcaagtga gggggattcc atccggaccc ccgcgccacc tgcgtgagga gccacgtcat
    15841 gatgtacaac aacagcgccc ggcagcccga cccggagccg cttccgaact ggacaagggg
    15901 tgcagggcgc ctaccgggcg cttcggaatc cagtgccgtg aacggtgccg cgaacgattc
    15961 ccacgtcgtc ccgatcaccg caggtcacac cgcccggcca aggggttccg ggaaggtcga
    16021 cacctctctc ccttcccctg agacgtcggc gaaggggaag aggtccgctc ccacggccgg
    16081 gaaggtacgg gctgacgcgc tgcggatgct gggatgtgtg cgggtagcga cggtccgtca
    16141 gctggcccaa gtgagcacag ccgaaggtcg ggatggccgg tcgtatgtgc gtcgggcgat
    16201 gaagaggctg gcggagctgg ggctggcgga tacgaacggc aaggccgggc ggcacccgat
    16261 ctggaacctg acagtggcgg ggcagaaggc tttggccgac ggtaacgagc tccctccccg
    16321 accgaaggcc ggcaccggag cgaaggccgt cgcggccggg ttcggtccgc acgggatcgc
    16381 ggtggcggac acgatcctcg ccttcggctg ccgggaccat ctgaccggct ggcaggtgga
    16441 ggtcaaccac gccatcaagg agaccggcct cagcttcaac accgacgccg tcctcgcgtg
    16501 gccgaccaag accagcgagg tgcgcctctt cgagctcgac aacggcacca tgccccaggc
    16561 ccggctcgcc cgtgaggtct gggactacga gcgctacgcc gggcaccgcg tctgggaagg
    16621 cgcccgcggc acgatcggcg gcacgttccc gttctggcag cgccaccgct acacccgctc
    16681 cgagacgttc cctcgactgc atgtagtcct ggcgggcaag gcggagcacc tcctcgacaa
    16741 ccgcccccaa gcgctcgccg ccgacgtccg cggcatcacc atcgaggtct gggtgaacac
    16801 cctgccccga ctgaagcgcc gggagccctg gtacgagatc ggcacggatg acccggaccg
    16861 gcgccgccag cgctacccgg agacgctcgg ccgctgaggt tgcgcacaac gccgggcacg
    16921 cccccgttgc ggagggggct gtccggcgtc cggccccggc gggcgggacg ggcgccgaag
    16981 tccccgtgcc accgcgcggg acgaaccggg tccaggcaca cactgcgccc cggacccggc
    17041 gtaccaagga gacgtcgaca ccactaccag cggaggagac ccgagcatga ggcacagcag
    17101 gcgggacaag aaccatgaca tcgacatcgc ggctgcggct gcctggccgg aacggatctg
    17161 ttcccggctt gccgcggcgg ccaggaacgc cgagccgagg tggcggccgg ttgcggcgtc
    17221 gaagacttcg atggtgtcgt cgtgatgggg caggtgccgt actgacacct tggtgccggt
    17281 acggccgttc atccacgggg cgaggtagtc ccggcggcgc caccgcaccc cgctggtact
    17341 gatcgtgtac gtacgcccgt cgtcctccag agcgaatgtc gccagctgcc ccgcggccac
    17401 gtccgtgagt ggtgtcgcgt cggcctgcca cgtctggagg ggggttttcc cgttgagcgc
    17461 ggacgggtgg tggcgggtgt tccaccaggt cacccagtcc agcagcagcc ccacgaacgc
    17521 ctcatacgtc aggggcgggg catcggggtc ggcgagagcg ccgccggtga gtctctggcg
    17581 gccggtgtag cgggggaggg agacgaggaa catctcctcc accgcgtcgt tcagcgcctc
    17641 gatagtgccc ttcaggtgcg gtgtgtaggc gggcaggtcg gtgacgggga cggcgagcgc
    17701 gcccatcgcg gcgctgaccg cctggcacag gaactccttg ccccggtcca cccggatctc
    17761 accaggaagc ccgcccaccg gcccgaacgg ctcgctgcgg gtgatcgcga tgcgcaatga
    17821 cgccagcacc gcgtcccggc tcggtgcgtg tgcggtgacc gcgaccccgg tgatcgcctt
    17881 ggtggcgcag tcgatgaacc aggtcaccca cggcgtggcc agctcaccct cgacatcgac
    17941 ttcgacgggc acgtgcttgt ggtccccttc ccacgccgcg ttgcggtgcg tggccggccg
    18001 ctgcccgaac acgtcatgcg cgcgccgcgc ggcttccccg ctcttgagcc cggcccgctc
    18061 accgcgggtc aggtcccggc ggatcgcccg gtgcaacgtg gagagcgacg gcaccgcggg
    18121 cgcgtccgga tccccggccg cccgctgcac cagttcggcg tggacccggg aggcgttacc
    18181 gccccacagc gccagcagcc gcctcacttc cgtggtgacc gtgaaatgcg acgactccac
    18241 ccgggcgagg cgatggtcct cccgggcagc ggccagccac cgccacaccg tccgctccga
    18301 cttccccaac gcctgcgcca ccagacgcac atgcgcggcc ctcagctcac cacgcccgtc
    18361 gaggtccagc agccggggca tcgccgccgc ccgacccgac gccggcggga acaccgccac
    18421 cgggccgtct tcagggtcct cgccgcgccg tcccggcatc atggcccctt cccacgagca
    18481 ctgggcggca cgctctgccg ccctggcccc aggtatgcca ggcgttcagc atccgactga
    18541 ccggtttcgg catacgactg acagcaaccg tcgccatccg gtacggcgtg gcggcggccc
    18601 gccggtagaa cggcaggccg gttgggcaag cctcgcctgg aaacgacacc tccccacgcg
    18661 aaagcagagg agagaggtct gttccatccc cggcgccgcc gagatacgca agcggctgac
    18721 ccgccatggc cgctgaagcc tctaccgctg aatagcccgg cctgccaggc gatggacggg
    18781 cgccgcgctg acatcttcat gagttcgggc ccacggcaac tgccagcatc tgctgtgggc
    18841 ttcctggtag gccatctgta gtgatatcac tgcggtgcgt gatcttatgt gacaggtcgg
    18901 gggcggaata tggcaggagc acttcagccg ggcagagacg gagcccggcc ggtcctcgag
    18961 ggctttccgg agcccaaatc accagaggtc gtcgtggttg ccccgccgac ccagagcgct
    19021 cccacgccca caccccaggt gtacctgcag tacatctatg acgcggacga ctgggaggac
    19081 ttcaccgtcg agtgggtccg ccagttcggc tcatggtctg gtcgccccta cgtccgagtg
    19141 cagcggatgg gtggggccgg cgaccgcgga gcggacgtcg cagcctgtct ctcagcgcaa
    19201 gggacggcgg gcgagtggca ctgctaccag tgcaagcact acgtcaagcc gctcgggcaa
    19261 tcagacgcct tcccagagat ggtcaagatc ttcgtcgcga agatcctcgg cacgtacgag
    19321 ctgcccacgc gctatgtctt cgtcgcacca aagattggca cgggactcga acgactcctg
    19381 ctcaacccac cccagctgaa ggacgagttc ttcgcggcgt gggacgacaa aaactccaag
    19441 ctcgggacca agcccaagct caccccggag atgcgtacag ccgtgggcgc gctggcgcag
    19501 gcgacggact tctcgatgtt cgaagcccgg aacctcgaag agattctcaa actgcacgct
    19561 gcgacccccc accacgttag gcgcttccca caaccgctta agcagcgccc tgccgccgat
    19621 ccggccccac ctgaccaggc accacacgaa gctgtctacg tccgcaagct gctggacgcc
    19681 tacaacgcga agcacggcct cgccttggag acgctgcaac aggcccgcga ccatgcgaaa
    19741 gtcagcggcc atctcttccg acagcgtgcc gccttcttcc acgccgagtc actctggcgt
    19801 ttcgcccagg agagcgtccc ggaagcgacc tacaccgcga tcgaaaccga cctatacgac
    19861 gccgtgatcg agatcgaaga ccgcgaccat gccagcggct acgcacggct ggaagccgta
    19921 ctggacgcgg ctgtcgccca cacaccgaac ccggcgaaca tcctcgcccc cgtggtgaag
    19981 gtcatcgacc tcaagggcat gtgccaccgt ctggccaacg atgatcggct gacctggtgc
    20041 aaagaggagg ccctgtgacc cccctcaaca gccccgtgga ggccgggatg cgcgctctgg
    20101 tcctcctgtc agaggccttc ccccgtcggc tggacgtcgc ccagctcgtc tacctggacc
    20161 acgccatgct ccacagcggc gacctcgacc acggaccggc cagcctccac cccgatctcc
    20221 ccgccggccc cggcgagctc ggcctgcgcc gccaccttat cgagcagggt ctcatggtcc
    20281 tgctgcgtgc tggcctcgcc gacatgacga ccaccgacga cggcttcatg tacggggcca
    20341 cggacgaggc agcgggcttc ctcagtgccc tggagtcccc ctacgtcggc cagctcatcg
    20401 agcgggccga ctggctgacc agtacctaca tgcatgaagg aacggacgtt cgcgagggca
    20461 tgaagcagat cacccagcgc tggtctggcc gctttcaggt gagtaccgcc gacctgggag
    20521 aagaggacgt cctgtgaata ggctgacgct cgtacacctg accttcctcg gcatggacaa
    20581 gcccccagca gcgatggaat tcagccctgg actgacggtg atctacggag cctccgacac
    20641 gggcaagtcc tacgtcgaag aggccgtgga ctacatgctg ggcgccagcg aactcaagtc
    20701 agttccggag ggcgacggct acacccgcat ccttctgggc ctgcgcgtga gcgacggccg
    20761 cagcctcacc ctgtcccggg ccatcggcgg cgacaccatc gaggtgttca accacgatct
    20821 ccgagaggtg ccatcggagc cagcggacga gaccctcaag tcgaagcaca acgcaaagtc
    20881 gaagaagaac atctcccgct acctgctgac cgtgctgggg atcgacggcc gaagggttct
    20941 ccagaactcg ggcggcaagg cgttgccgct caacttccgg gacttggccc gcttggccgt
    21001 cgtcaacgac acacgcatgg ccgaccagag gtcccccgtg ctcggcaccc ggatgccaca
    21061 gaacgagacc agggagaagt cggtcttcaa acttctcctc agcggacagg aggagccgga
    21121 gcgccctgcc gcgcccagca atctggagaa gcagttcggc aagggcaaga ttgcggtcat
    21181 cgaccacctc atcgacgaga cccgcgagaa gctcacgatg gaggcgaacc agtcgcaact
    21241 gcgggagcgg ctcgaccgcc tgcaggcgtc cctgggtgag gtgaccgccg ccgccatcga
    21301 gctcgctgag gtccgca
//
