LOCUS       NZ_LFBV01000001        21095 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces uncialis strain DCA2648 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_LFBV01000001
VERSION     NZ_LFBV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces uncialis
  ORGANISM  Streptomyces uncialis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2018837)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Cloning and characterization of the uncialamcin biosynthetic gene
            cluster
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2018837)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33410, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-MAY-2015
            Assembly Method                   :: CLC Genomics Workbench v. 8.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905345.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:03:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,456
            CDSs (total)                      :: 7,371
            Genes (coding)                    :: 7,214
            CDSs (with protein)               :: 7,214
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 5 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 42 of 157
            Pseudo Genes (incomplete)         :: 143 of 157
            Pseudo Genes (internal stop)      :: 7 of 157
            Pseudo Genes (multiple problems)  :: 33 of 157
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:56:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1768942
            Orig. end                         :: 1790037
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LFBV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21095
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11095](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11095
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            768..1490
                     /locus_tag="AB852_RS07590"
                     /old_locus_tag="AB852_07440"
     CDS             768..1490
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072146.1"
                     /locus_tag="AB852_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07440"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_073784770.1"
                     /transl_table=11
                     /translation="MNTLAIDGLTDLWDRVFSTQPDPDLWVVVATAVAALLVVVPHPLW
                     RLSRNAITIAHEGGHGLVALATGRRLDGIRLHSDTSGLTVSRGKPTGIGMILTAAAGYT
                     APPLLGLGGAALLGAGYITLLLWLATGLLLVMLVMIRNAYGVLTVILSGGTFLLVSWLA
                     GPQVQAAFAYAVVWFLVLGGVRPAFELQAKRRRGGAGDSDADQLSRLTNVPAGLWFFLF
                     HAVSLCSLIGTTRWLLRV"
     gene            2360..2947
                     /locus_tag="AB852_RS07595"
                     /old_locus_tag="AB852_07445"
     CDS             2360..2947
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384595.1"
                     /locus_tag="AB852_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07445"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_073785610.1"
                     /transl_table=11
                     /translation="MTWYHAPHPALTLAVSHGAGGGIGARDLQALAATLPPNGVTVALV
                     EQPWRVAGKKLAPAPKTLDAGWRDLWPALTTPGLPVIAGGRSAGARVACRTAHDLGAHA
                     VLALAFPLHPPGRPDRSRAGELLGARVPTLVVQGGNDPFGHPEEFPDGAHELVPVPSAD
                     HSFAVPKRAPVTQDETLLTLTDAVVEWTARLR"
     gene            3322..3987
                     /gene="sigR"
                     /locus_tag="AB852_RS07600"
                     /old_locus_tag="AB852_07450"
     CDS             3322..3987
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="AB852_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07450"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_178390947.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAERPEESTAERNARFERDALEFLDQMYSAA
                     LRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQR
                     SAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEFRIAVYLADVE
                     GFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGEANEAKGSGS"
     gene            3984..4328
                     /gene="rsrA"
                     /locus_tag="AB852_RS07605"
                     /old_locus_tag="AB852_07455"
     CDS             3984..4328
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061545.1"
                     /locus_tag="AB852_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07455"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_073784775.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCTEVLDHLYEYLDREMPEGDCTKFETHFEECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPTDLRAKVMGRIDLIRSGESGDSVTDPLPGPYTKSAE
                     KDVTASAEGA"
     gene            4575..5945
                     /locus_tag="AB852_RS07610"
                     /old_locus_tag="AB852_07460"
     CDS             4575..5945
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674892.1"
                     /locus_tag="AB852_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07460"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_073784777.1"
                     /transl_table=11
                     /translation="MRSVPALARAYILGAALAALFCAAPALAAAVPGAAGSPDAPSVPW
                     LAVALLAALYAGCEQLPRCRFMGRHAPRGMGMFFPVLLAGAFLLPPAAAALVGVPGALL
                     ARVERRPAGPRRIWHAAQLALACWAAALAHQALGGPGAVGGPAGPDFPYALAPAAAAVV
                     VFCAVLTVLDGGILVLAERVPARRAWRGRFWPVLAPVSVHGLVGLMMTVLWRSPYGPGA
                     ALLVLLPMYISCWLFAQYHRERAAHQSTIRALVQAVDLKDGYTRGHSERVGQASVMIAQ
                     ELGMDDSRVETLRFAGILHDVGKLGVPTRLLRKDGPLTPQERRVIELHPEYGHEITRGI
                     GFLGEARAAILHHHERVDGSGYPYGLAGDRIPECARVVAVADAFDAMTSTRSYSRARSV
                     PKAVAELERCAGAHFDPRMVGALVRALDRHGWHPSVTADGPDLPAPRATGSPAGSPS"
     gene            6215..7492
                     /locus_tag="AB852_RS07615"
                     /old_locus_tag="AB852_07465"
     CDS             6215..7492
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376700.1"
                     /locus_tag="AB852_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07465"
                     /product="HD domain-containing protein"
                     /protein_id="WP_245876682.1"
                     /transl_table=11
                     /translation="MLVLGSAGSLTVWAIGVTVWAGVHERGTALAFGLLIAVGELARTG
                     GTAEGERDTAPLAAAGALAYALLGENGGGATHHGVAQVVTVTVAAGLLGGLPHLAAGRG
                     PAPEQLARRTLSVAFAAVCFQPLYNTGALADLVHPGPVYALWMTGVLAVTALCDAVLAA
                     ALARARTGWPFAPLLRDELRAMIGIGSAVCATGAVMALTVAVAGLWALPVFSLPLLLTQ
                     LSLRRYAAVRLTYRQTIASLARSTEIAGYTPHGHARAVAALSRAVGRELGLSRSALTVL
                     EHAALMHDIGQLSLVDPVPAGATASLPAEAQRRIARLGGAVVRQTGVDPEVALIVERQA
                     DPRCEQPLAARIVRTANAYDELVRAQGPGGPLAALERLRLATGHDHQPEVVEALARALA
                     QRGSGALLPWDTARPPGGAAGAGAVT"
     misc_feature    6242..6257
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.48"
                     /tool="antismash"
     misc_feature    6263..6278
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            7692..8681
                     /locus_tag="AB852_RS07620"
                     /old_locus_tag="AB852_07470"
     CDS             7692..8681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089486.1"
                     /locus_tag="AB852_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07470"
                     /product="hypothetical protein"
                     /protein_id="WP_073784780.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRETGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGRPGSGGAAGEPVGMELGSAAVRLSPEGEAEVVWGRRLDPARIEVLS
                     IPLPSSGRRWGEVVLHDGVPHGERTTAAGHVYPVFDEIELWAPSPVPTWVVLLEADDEE
                     DRDALERLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGQPGPL
                     GHVTDGHQWVPERECGIAAPASLVRGLLDGWVSDSPDTRDWRDLEEVC"
     gene            8909..9559
                     /gene="def"
                     /locus_tag="AB852_RS07625"
                     /old_locus_tag="AB852_07475"
     CDS             8909..9559
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="AB852_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07475"
                     /product="peptide deformylase"
                     /protein_id="WP_073784782.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHSGVLPVDDEGFVIDTEDCEAREEAYRARGTSRPIT
                     VVGNPVLHTECEDITTFDDELAGLVDDMFASQRTAEGVGLAANQIGVGRKVFVYDCVDD
                     SGDRHVGVVCNPVLQDLPADQRSLDDSNEGCLSVPTAYAELARPDFAVVTGQDEKGNPI
                     KVRGRGYFARCLQHETDHLYGRLYIDRLSKRDRKDALRQMEEGTPRYPVVAND"
     gene            10001..11095
                     /gene="cyc1"
                     /locus_tag="AB852_RS07630"
                     /old_locus_tag="AB852_07480"
     CDS             10001..11095
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="AB852_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07480"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_107499138.1"
                     /sec_met_domain="T1TS (E-value: 2.8e-56, bitscore: 188.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAFSYSTAATQTAVPPALALPVIEKEFPRQLHPYWPTLQETTRA
                     WLLKMGLMPADKVERYADGLCYTDLMAGYYLGAPVEVLQAIADYSAWFFVWDDRHDRDV
                     VHRRDAAWARLRDCLHAALDAPWRHLQHEDALVAAFADSMIRLYSFLGESWNARFAAHF
                     HEVIEAYDSEYRNRTTGRIPAVTEYLELRRLTFAHWIWLDLLEPAAHHEIPRSVLENPA
                     YRKAGLACQDFAAWYNDLCSLPKELAGDEYHNLGISLIKHEGMTLEDAVTEVRRRVNGC
                     ISEFLAAEQEVAVLIGELRDGTWRGEPLADAVALNISNMRNWFSSVYWFHHESGRYQVD
                     SWADRSTPPYISDQGERPGSAGIR"
     misc_feature    complement(10004..10022)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            11092..12465
                     /locus_tag="AB852_RS07635"
                     /old_locus_tag="AB852_07485"
     CDS             11092..12465
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378233.1"
                     /locus_tag="AB852_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07485"
                     /product="cytochrome P450"
                     /protein_id="WP_073784786.1"
                     /sec_met_domain="p450 (E-value: 1.4e-70, bitscore: 235.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGPTPRTAGTDGRNAPPPPYAKGGAPLLGHAWNLVRDPLRFVA
                     GLRDSGDVVRLRLGPGTAYAVCAPELVAALLKSPDYEVGGPLWDTMELLIGKGVATSNG
                     PLHRRQRRMIQPAFRPERIAAHAPVMAEEAAAMADRWSPGATVDIGDEVFRTAVRIVTR
                     SLLHVDSIDERVDRLGGSLHTVFGGLYRRMILSAGPFWKLPLPAHRRFEVALADLHRLV
                     DEIVRERRMSGTDRGDLLSALLRAKDDNGETLNEQEVHDQTVSLLVAGAENVASTLTWT
                     FQLLAEHPEEEKRLRAEVLSVTGGRPVTFGDLPKLGHTRNVITEAMRVRPAVWILTRRA
                     VADSVLGGYRIPAGADIVYSPYAMQRDPRAFARQLEFDPDRWQPGTQADRGGPAMMPFG
                     TGNRKCPGDHFSIVEMAIVLATVVPRWSLSRLRETDTAPRIGITLKPRRPRLRAVPVA"
     gene            complement(12529..13503)
                     /locus_tag="AB852_RS07640"
                     /old_locus_tag="AB852_07490"
     CDS             complement(12529..13503)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561567.1"
                     /locus_tag="AB852_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07490"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073784788.1"
                     /transl_table=11
                     /translation="MLNNVAVVLLDGVHPFELGVVCEVFGLDRSEQGLPVYDFAVVSAE
                     GPELSTHAGFSVRLEHGLERLEEADLIAIPAGEDYGSREFPEPLLDALRRATARGTRVL
                     SVCSGVFVLGAAGLLDGRRCAGHWRHADELAIRFPRARVERDMLYVDEHPVITSAGSAA
                     GIDSCLHIIRQEHGSEVANALARRMVVPPHRDGGQAQYVERPVPTTRCDTVGEVLVWME
                     RHLDRAVTVEELADRAHMSPRTFARRFQQETGTTPYRWLLRQRVLLAQQLLEGTDETVD
                     SVAGRTGFGNGATLRHHFLRVLGTTPNAYRRTFRGPRPLETAP"
     gene            13597..13773
                     /locus_tag="AB852_RS39580"
     CDS             13597..13773
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458164.1"
                     /locus_tag="AB852_RS39580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_178390948.1"
                     /transl_table=11
                     /translation="MNTLLDYSVVTLVLALLLGPVTPGYLRERRIDRELRDAGRGRPGH
                     PEGRPGRSLDLAA"
     gene            complement(13795..14838)
                     /locus_tag="AB852_RS07645"
                     /old_locus_tag="AB852_07495"
     CDS             complement(13795..14838)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009307556.1"
                     /locus_tag="AB852_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07495"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_099284464.1"
                     /transl_table=11
                     /translation="MTTTPTEPAAAAPRERNLLDPGFELTLRPMRYPDFYERYRDAIKN
                     TWTVEEVDLHSDVADLAKLSPAEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEAR
                     LYLSRQLFEEAVHVQFYLTLLDTYLPDPEDRTAAFAAVENIPSIREKAEFCFKWMDSVE
                     KLDQLETQADRRRFVLNLICFAACIEGLFFYGAFAYVYWLRSRGLLHGLATGTNWVFRD
                     ETMHMSFAFEVVDTVRKEEPELFDDKLQEQVTDMLREAVEAELQFARDLCGEGLPGMNT
                     ESMRQYLECVADQRLERLGFAPVYGSQNPFAFMELQGVQELTNFFERRPSAYQVAVEGK
                     VGFDDEF"
     gene            complement(14838..17267)
                     /locus_tag="AB852_RS07650"
                     /old_locus_tag="AB852_07500"
     CDS             complement(14838..17267)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984456.1"
                     /locus_tag="AB852_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07500"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_073784792.1"
                     /transl_table=11
                     /translation="MTIAPADPASVVGQAPATTAQDQQTRPSDGPGAALLRTLTDLTAD
                     LPDADPGRVAAAALRGRSARADESELRELATEAAAGLISEDPAYSRLAARLLTVSIAAE
                     AASQGVLAFSGSVATGHREGLIADRTAAFVTKYSDRLDALIDTTADDRFGYFGLRTLHS
                     RYLLRHPITRKVVETPQHFLLRVASGLAEDDSVRALDEVAALYRLMSRLDYLPSSPTLF
                     NSGTRHPQMSSCYLLDSPQDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGT
                     NGHSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRT
                     HNLNLAHWIPDEFMRRVDQDGTWSLFSPSDVPELVDLWGDEFDAAYRRAEAAGLARKTI
                     PARDLYGRMMRTLAQTGNGWMTFKDAANRTANQTAEPGHTVHSSNLCTEILEVTDDGET
                     AVCNLGSVNLGAFVTGEGDDGIDWERLDSTVRTAVTFLDRVVDINFYPTEQAGRSNSRW
                     RPVGLGAMGLQDVFFKLRLPFDSPEARALSTRIAERIMLAAYEASASLAERNGPLPAWD
                     KTRTARGVLHPDHYGVEPHWPERWDALRARIAVTGLRNSLLLAIAPTATIASIAGVYEC
                     IEPQVSNLFKRETLSGEFLQVNSYLVNELKELGVWDARTREALRESSGSVQDFRWIPEE
                     VRALYRTAWEIPQRGLIDMAAARTPFLDQSQSLNLFLETPTIGKLSSMYAYAWKSGLKT
                     TYYLRSRPATRIARAAGSSAAAERPAPTTIPVQQAAPDADAIACSLENPESCEACQ"
     regulatory      complement(17426..17503)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17518..17531)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(17525..17539)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17557..17571)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 26.4"
                     /tool="antismash"
     misc_feature    17804..17817
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.19"
                     /tool="antismash"
     misc_feature    17859..17874
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.41"
                     /tool="antismash"
     gene            complement(18066..18842)
                     /locus_tag="AB852_RS07655"
                     /old_locus_tag="AB852_07505"
     CDS             complement(18066..18842)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003961764.1"
                     /locus_tag="AB852_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07505"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_073784794.1"
                     /transl_table=11
                     /translation="MASEVSRAGTSATAETATTGRTARVPKYYRLKKHLLDMTETLTPG
                     TPVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTE
                     DMRAQGLEPTSQLLDIGYITADDTLAGLLDIATGGRVLRIERLRLASGEPMAIETTHLS
                     AKRFPALRRSLVKYTSLYTALGEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLM
                     LSRHSLDGGGRPVEWVRSVYRGDRYKFVARLKRPTD"
     misc_feature    complement(19002..19017)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.28"
                     /tool="antismash"
     misc_feature    complement(19026..19041)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     gene            19129..20409
                     /locus_tag="AB852_RS07660"
                     /old_locus_tag="AB852_07510"
     CDS             19129..20409
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675602.1"
                     /locus_tag="AB852_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_07510"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_073784796.1"
                     /transl_table=11
                     /translation="MKRKLIAAIGVAGMLFSVAACGDSDSGDKKESKGTDTKGKTLVVW
                     SMDGSTPDPWKKAVAADFEKKTGSKIKWESQVWNGIQQKITTALSESSPPDVIEIGNTQ
                     TPAYAATEGLAELGDLKTEIGGEWTEALNKSSIYNDKQYAVPWYFANRVVLYNKKIWAE
                     AGLKDTPKTRDDFFKALDTIKEKTKAEPLYMAGQNWYFLDGLIIGKGADLVKKEGDKYV
                     SNLSDPKVGEAMELYKKYASYSSAPKDKDEATPQQADVFANGKTAMFIGNASEATIAVK
                     ANAKIEKDIGYFTIPGESAEKPESVFLGGSNLAVPLRSKNQELAKEFLKIALADEHQIE
                     FSKLMGFTPNKASLLPKVAGSNAGLDAAAPAAAFGGTTPLIPEWAAVENVPNPIKDYMT
                     AVLNGKSHADAAKDADAEINKRLAQGS"
ORIGIN
        1 gcccggtcgg cggcggctcc agcagcgcac gtacctcgcc ggggtcggta cgcgccgggt
       61 cgagccacgc gtcccagcgg tccggcgtga gcatcagcgg catccgcgga tggatctccg
      121 cgagagtgcc cggcccgtcc ccgtccccgg ccgcgcccgc gagcggcgtg gtctccgcct
      181 ccgtggtgat gatcgtgcac gtcacccacc acgccagcgg atgctcgtcg ggcagcgtac
      241 ggtcccgcca gaactcgtac agcccggcca tcgcgaacac cgaaccgtcg gccggggtca
      301 cgaagtacgg ctgcttgcgc ggccgcttct tacgcccctc gacctccagc tcccgctccg
      361 ccgccgcggt cacccactcg tagtagccgt cggcgggcag cagacagcgg cgcgccgtga
      421 agggacggcg gaacgagggc ttctcgtgca ccgtctcggc gcgcgcgttg atcatccggg
      481 ccgcgccctc gggggtcttc gcccacgacg ggacgagtcc ccacttgagg gtgcgcaact
      541 ggcgaaccgg acgcgggtcc tcggcgtcct tcacaggacg gtccagtacg gcgaagacct
      601 ccttggtcgg cgcgacgttc cagtccgggg ccagggtctc cgtcggctcc cacgcggtga
      661 tcccgaagat ccccgcgagg tcctccggcc gacggctcga cgcataacgt ccacacatac
      721 atgtcacact gccagacccc cgcaccgttg agggagccgc ccggaaaatg aacactctcg
      781 ccatcgacgg cctgaccgac ctgtgggacc gcgtcttctc cacgcagccc gacccggacc
      841 tctgggtggt ggtcgccacc gccgtcgccg cgctgctcgt ggtcgtgccg catccgctgt
      901 ggcggctttc ccgcaacgcg atcaccatcg cccacgaggg cgggcacggt ctcgtcgccc
      961 tcgccaccgg gcgcaggctg gacggcatcc ggctgcactc cgacacctcc ggactcaccg
     1021 tcagccgcgg caagcccacc ggcatcggca tgatcctcac cgccgccgcc gggtacaccg
     1081 cgcccccgct gctcgggctc ggcggggccg cgctgctcgg ggcggggtac atcacgctgc
     1141 tgctgtggct ggccaccggg ctgctgctgg tgatgctcgt catgatccgc aacgcgtacg
     1201 gggtgctcac cgtgatcctg tccgggggga cgttcctgct cgtctcctgg ctggcgggcc
     1261 cccaggtgca ggccgcgttc gcgtacgccg tggtgtggtt cctggtgctg ggcggggtac
     1321 ggcccgcgtt cgagctccag gcgaagcggc ggcggggcgg ggcgggtgac tccgacgcgg
     1381 atcagctctc gcggctcacc aatgtcccgg cgggcctgtg gttcttcctc ttccacgcgg
     1441 tgtcgctgtg ctccctcata ggaaccacga ggtggctcct ccgggtatga cctccggcgc
     1501 tccgaggtcc gtccggctgg gcgtacttgt ttccggtgcc gtcgttcgga gggtgcgcgg
     1561 ttcctcgcgc ccctggggtt ccacacctgg gcgtacttgt cccggtgcag gtacttcgtg
     1621 ggtgcgcagt tccccgcggg tcgccttcgc tcgggcccct gggtttcgtg cgcggggcgt
     1681 actttgtccc tgcgcgggtc ggacgtgggt gcgcagttcc ccgcgggtcg ccttcgctcg
     1741 cgcttcccag gttcgtccgg ctgggcgcac ttgtttccgg tgccgtcgtt cggagggtgc
     1801 gcggttcctc gcgcccctgg ggttccacac ctgggcgtac ttgtccccgt gcaggtactt
     1861 cgtgggtgcg cagttccccg cgcccctgaa ggggcacccc cttcctcccg cagtcgctcg
     1921 gctgcgggag ggggtgggcg ggactctctg cccgcagact ccgatgctct tcagtaggac
     1981 cagtgggacg tcgtaccgag cgcgttggag cgaggacgga gaatcccgac cggcaccgac
     2041 ccgaagaaca agccggacgc gccccaaagg ggcgcgggga actgcgcaaa aacgacgagc
     2101 gacggcacag gaacaagcgc gcccacccgg acagacctag gaagcgcaag cgaaggcgac
     2161 ccgcggggaa ctgcgggaaa ccaccgaacg acggcacaag gacaagtacg ccccgcacaa
     2221 gaaacccaag gggcaggatg cccccgtgac ctccaacgac agcaacgaca gcaacgacag
     2281 caacgacagc aacgcaagaa caggcgcccc cggccccggg gccccggaga ccgtccccac
     2341 cggaccgggg gacgcccgga tcacgtggta ccacgccccc caccccgccc tcaccctcgc
     2401 ggtgagccac ggcgcgggcg gcggcatcgg cgcccgcgac ctccaggcgc tggccgccac
     2461 cctccctccg aacggcgtga cggtagccct cgtggagcag ccctggcgtg tcgccgggaa
     2521 gaaactggcc cccgccccga agaccctcga cgcgggctgg cgggacctgt ggcccgccct
     2581 caccaccccc ggcctcccgg tcatcgcggg aggccgcagc gccggcgccc gggtcgcgtg
     2641 ccgcaccgcc cacgacctcg gcgcccacgc cgtcctcgcg ctggccttcc cgctgcaccc
     2701 gcccggccgc ccggaccgct cacgggccgg ggaactcctc ggcgcccggg tcccgaccct
     2761 ggtcgtccaa ggcgggaacg accccttcgg gcacccggag gagttccccg acggcgccca
     2821 cgaactcgta ccggtgccgt ccgccgacca ctccttcgcc gtgcccaagc gcgcgccggt
     2881 cacccaggac gagaccttgc tcaccctcac ggacgccgtc gtggagtgga ccgcgcggct
     2941 ccgctgaccg cccggccgac ccgcccaccg gcggggaatg ccgggccccc gggtgctgtt
     3001 gtggcgaaca gaaggcgtgc acacggctcg gtccggaagg accgccgaag ccggtgcccg
     3061 cccggtccga ccgatcgaga gggagaacac cgcatgggtt cgatcacctg cccgagccgc
     3121 agtggcacca cgggtctgaa ctggtccgtc ctgccctcgg ccatcggtgc ccccacccgg
     3181 gcgcccggcg gtccggacct gtcggcaccc gcccttcccg cgaccccggc cccgtacggc
     3241 ccgaccgccc cgtcgacccg tggtcgacta ttctccgaag cgggtgggac cggtcccggt
     3301 tccacgacag cgcctgagga ggtgggtccg gtcactggga ccgacgcggg gaccgagcac
     3361 ggccaggcgg aacggcccga ggagtcgacc gccgagcgca acgcccgttt cgagcgggac
     3421 gccctcgaat ttctcgacca gatgtactcc gcggccctgc gcatgacgcg caacccggcc
     3481 gacgccgagg atctggtgca ggagacgtac gccaaggcgt acgcgtcgtt ccaccagttc
     3541 cgtgagggca ccaacctcaa ggcgtggctg taccgcatcc tgacgaacac cttcatcaac
     3601 tcgtaccgca agaagcagcg cgagccgcag cgcagcgccg ccgaggagat cgaggactgg
     3661 cagctcgcgc gtgccgagtc ccatatgtcc accgggctgc gctccgccga gtcgcaggcg
     3721 ctggaccatc tgccggactc ggatgtgaag gaagccctcc aggcgatccc cgaggagttc
     3781 cgcatcgcgg tctacctcgc ggacgtcgaa ggctttgcgt acaaggagat cgcggacatc
     3841 atgggtacac ccatcggcac ggtgatgtcc cggctgcacc ggggccgccg ccaactccgc
     3901 ggcatgctgg aggactacgc gcgtgatcgc ggtctcgtcc cggccggcgc cggagaggcg
     3961 aacgaagcga aaggctcggg ctcatgagct gcggagagcc gcacgagacg gactgcaccg
     4021 aagtactcga ccatctctac gagtacctcg accgtgagat gcccgagggc gactgcacga
     4081 agttcgagac gcacttcgag gagtgctccc cgtgcctgga gaagtacggt ctcgaacagg
     4141 ccgtgaagaa gctggtgaaa cggtgctgcg gtcatgacga cgtacccacc gatctgcggg
     4201 ccaaggtcat gggccggatc gatctgatcc gttccggtga gtccggggac agcgtgaccg
     4261 acccgctgcc cggcccgtac acgaagtccg cggagaagga cgtcaccgcc tccgccgaag
     4321 gcgcctgagc cgcgccttcc tcccgctgcc gctccacccc cgccgagggg gagcggcacg
     4381 cctggggtca agccgccgcg ccgtggggaa tgggtgcgac gggaaaatca cccgaatgtg
     4441 ctaatccccg tgggggaggc cgggcgaatc cgctgatgcc gcccgaacgc cacccggcga
     4501 cccctattct ccggagcctg tgacgggcgc gcccggcccc tttcgggcgg ccgggcccgg
     4561 gggaggagcg gtggatgcgg tcggtacccg ccttggcccg tgcgtacatc ctcggcgccg
     4621 cgctggcggc gctgttctgc gcggcgcccg cgctggccgc cgccgttccc ggggcggccg
     4681 gctccccgga cgccccttcg gtgccgtggc tcgccgtcgc cctgctcgcc gccctgtacg
     4741 cggggtgcga gcagctgccg cgctgccgtt tcatgggccg ccacgccccc cggggcatgg
     4801 gcatgttctt cccggtcctg ctcgccggag cgtttctgct gccaccggcc gccgccgcgc
     4861 tcgtcggtgt gcccggcgcg ctgctggcgc gggtggagcg gcggcccgcc ggtccccgac
     4921 ggatctggca cgcggcccag ctcgccctcg cctgctgggc ggcggccctc gcccatcagg
     4981 cgctcggcgg tcccggcgcg gtcggcggcc ccgccggacc cgacttcccg tacgcgctgg
     5041 cgcccgccgc cgccgcggtg gtggtgttct gcgccgtgct cacggtcctc gacggcggaa
     5101 tcctcgtcct cgccgagcgg gtaccggccc gccgggcctg gcgcggccgg ttctggccgg
     5161 tgctggcgcc cgtcagtgtg cacggtctgg tcgggctgat gatgacggtg ctgtggcgca
     5221 gcccgtacgg tcccggggcc gcgctgctcg tgctgctgcc gatgtacatc tcctgctggc
     5281 tgttcgccca gtaccaccgt gagcgggccg cccatcagtc gaccatccgg gccctggtcc
     5341 aggccgtcga cctcaaggac gggtacaccc ggggccacag cgaacgcgtc gggcaggcat
     5401 cggtgatgat cgcccaggag ctggggatgg acgacagccg ggtggagacc ctgcggttcg
     5461 cgggcatcct gcacgacgtc ggcaagctgg gggtgcccac ccggctgctg cgcaaggacg
     5521 gtcccctcac cccgcaggaa cggcgggtga tcgagctgca cccggagtac gggcacgaga
     5581 tcacccgggg catcggcttc ctcggggagg cccgcgcggc gatcctccac caccatgaac
     5641 gcgtcgacgg cagcggctac ccgtacgggc tggccgggga ccgtatcccc gagtgcgccc
     5701 gggtggtcgc cgtcgcggac gcgttcgacg cgatgacctc gacccgctcg tacagcaggg
     5761 cccgttcggt gccgaaggcg gtggccgagc tggaacgctg cgcgggcgcg cacttcgacc
     5821 cccggatggt cggtgcgctg gtccgggccc tcgaccggca cggctggcat ccgtcggtca
     5881 ccgccgacgg ccccgatctg cccgcccccc gcgccaccgg ctcccccgcc gggagcccgt
     5941 cgtgaccccc ggcaggcccc cggaggtgcc gggcaggccc gccgggaagt ccccgggccg
     6001 gacggtccgc ggcacggccg ccccgggacc gggcccgacc gccggaccgg accaggggga
     6061 cctccccggc gtgccaccac cggcccacgg gggcctcccc ggcgggccac cccaggcccc
     6121 gcccccgccc ggcccgccct ccggcaacgc ccgggacccc cgccccgccc cggccgcccg
     6181 cgcgcggggg tcgctgctgg gcaggctcac cgtcgtgctg gtgctcggct ccgcggggtc
     6241 gctgaccgtc tgggcgatcg gagtgaccgt ctgggcgggt gtgcacgagc ggggcaccgc
     6301 gctcgccttc gggctgctca tcgcggtcgg tgagctcgcc cggaccggcg gtaccgccga
     6361 gggtgaacgg gacaccgccc cgctggccgc ggccggggcc ctcgcgtacg ccctgctcgg
     6421 ggagaacggg ggcggcgcca cccatcacgg cgtcgcccag gtggtcaccg tgaccgtggc
     6481 cgccggactc ctcggcggac ttccgcacct cgcggccggc cgcggccccg cgcccgaaca
     6541 gctcgcccgc cgcaccctga gcgtcgcgtt cgccgcggtc tgcttccagc ccctgtacaa
     6601 caccggcgcc ctcgcggacc tggtccaccc cggacccgtc tacgcgctgt ggatgaccgg
     6661 ggtcctggcg gtgaccgcgc tgtgcgacgc ggtcctcgcc gcggccctgg cccgggcccg
     6721 taccggctgg ccgttcgcac cgctgctgcg cgacgaactg cgcgcgatga tcgggatcgg
     6781 ctcggcggtc tgcgcgaccg gcgcggtcat ggcgctcacc gtcgccgtcg ccggactgtg
     6841 ggccctgccg gtgttctcgc tgccgctgct gctcacccag ctctcgctgc gccggtacgc
     6901 ggcggtccgc ctgacctacc ggcagaccat cgcgtccctg gcgcggtcca cggagatcgc
     6961 cgggtacacc ccgcacggtc acgcacgggc ggtcgccgcg ctcagccggg ccgtcggccg
     7021 ggagctggga ctgtcgcggt ccgcgctgac cgtcctggag cacgcggcgc tgatgcacga
     7081 catcgggcag ctgtccctgg tcgacccggt accggccggg gccaccgcgt ccctccccgc
     7141 cgaggcgcag cggcggatcg cccggctcgg cggtgccgtg gtgcgccaga ccggggtgga
     7201 ccccgaggtg gcgctcatcg tggaacggca ggcggacccc cggtgcgagc agccgctggc
     7261 cgcccggatc gtacggacgg cgaacgcgta cgacgagctg gtccgggcgc agggccccgg
     7321 tggcccgctg gccgcgctgg agcggctgcg gctggcgacc gggcacgacc atcagccgga
     7381 agtggtggag gcgctggcca gggcgctggc ccagcggggc agcggggcgc tgctgccgtg
     7441 ggacacggcc cggccgcccg ggggcgccgc gggtgccggg gccgtgacat gagcccgcca
     7501 gacccggggc cccggggggc catacgtcgc ccgtcgctgg gtaacccatg ggtaatgagc
     7561 ggccgtccga ccgtccatgg ttggatgcga aggaaagacg ctacgagaag ggtgtccggg
     7621 ggcgtgaacc ctggctgtgt cggggcgggg caggaacccg cgccccccgg tgaggacggc
     7681 aggcgggaat cgtgaggatc ttcggcaagg gacggcaccg gccctccgcg tcctggcggc
     7741 aggccaccga ccgggcgttc acactgatcg gcgacggccg ctacgaggac gcgggggcgc
     7801 tgctgacccg cgccgccgac ctggagccct ggctgtcgga gtcctggttc aatctcgcgc
     7861 tgctgcacaa gttccggcac gactgggagc aggcccgcgc cgccgggctg cgggccgtgg
     7921 ccctgctgga ccgggagacg ggcgcccccg actggtggaa cgtcgggatc gcggcgaccg
     7981 ccctccagga ctggccgctg gcccgtcgcg cctggcaggc gtacgggctg aaggtgcccg
     8041 gccggcccgg gtccggcggg gccgccggcg agccggtcgg gatggagctg ggcagcgcgg
     8101 cggtacggct gtcgccggag ggcgaggccg aggtggtgtg ggggcggcgg ctggaccccg
     8161 cccgtatcga ggtgctgtcc atcccgctgc cgtcctcggg ccgccgctgg ggcgaggtcg
     8221 tcctgcacga cggtgtcccg cacggcgagc ggaccaccgc cgccggacac gtgtacccgg
     8281 tcttcgacga gatcgagctg tgggcgccct ccccggtgcc gacctgggtg gtgctgctgg
     8341 aggcggacga cgaggaggac cgcgacgccc tggagcgtct cgcggccgac gcgggcttcg
     8401 ccgccgagga ctggtcgtcg tcggtgcggc tgctgtgccg gatgtgctcg gagagccgga
     8461 tgcccagcga cgagggcgac ggcgagcacc tcgacccgca cgaccacagc gagccgggcc
     8521 agcccggtcc gctcggccat gtcaccgacg gccaccagtg ggtgccggag cgggagtgcg
     8581 ggatcgccgc gcccgcgtcc ctggtgcgcg ggctgctcga cggatgggtg tcggacagcc
     8641 ccgacacccg ggactggcgc gacctcgaag aggtctgctg acgcctcccg gacgggcctg
     8701 cggccggtgt ccggtccggg ccggtacccg tgtccggccg tgccctgcct cctcccggtg
     8761 tatccggccg tatcccgctc ggcggtgctc cggggcgccg taggctgtgt ggcggcagtc
     8821 gcccggcacc cgcgcatcgc ggaccggggg ctccccccgg gaggaacggt ccggggcacg
     8881 acacggttga ggaaggcgta cgtcggacat ggcgcagcag gacaccgatc agcagcacag
     8941 tggggtgctc cccgtggacg acgagggttt cgtcatcgac acggaggact gcgaggcgcg
     9001 tgaggaggcg taccgcgcgc gcggcacgtc ccgtccgatc accgtcgtgg gcaacccggt
     9061 gctgcacacg gagtgcgagg acatcaccac cttcgacgac gagctggccg ggctcgtgga
     9121 cgacatgttc gccagccagc gcaccgccga gggcgtgggc ctggccgcga accagatcgg
     9181 ggtgggccgg aaggtcttcg tgtacgactg cgtggacgac tccggcgacc ggcacgtggg
     9241 tgtggtgtgc aacccggtgc tccaggatct cccggccgac cagcgcagcc tggacgactc
     9301 caacgagggc tgcctgtcgg tacccaccgc ctatgcggag ctggcgcgtc cggatttcgc
     9361 cgtcgtgaca ggtcaggacg agaagggcaa ccccatcaaa gtacgcggcc gcggttactt
     9421 cgcgcgctgt ctacagcatg agacggatca tctctacggt cgcctctata tcgaccgtct
     9481 gtccaagcgg gaccgcaagg acgctctgcg ccagatggaa gagggcactc cgcgctaccc
     9541 cgtggtggcc aacgactgac cgtccgaggg atgttctccc ccggacgggg ggtgataaac
     9601 cccggcacgt cggaccgacc gcgaccccct gcgggtgatc gggacgggcc ggggaggggg
     9661 cggtgacccc tgaggtgggt gggtgcgcac ggtgtgcccg tgacggaggg tgttcccttc
     9721 cgccccagag ctacggcgcc cggccgggat gatttcccgc cgggcgcccc tcttgtgcgc
     9781 cggcgtgcgc cggtcgcgcc ttccgccatg tgtgatccga aatcagtcac gtaaggggat
     9841 gttctcggca gctcggggta gtgaatggag caaatctgtt ccctcatcgg gcacttgtgg
     9901 tgctgaatgg aatgtgcgcg gggatgcgcg acggcgtggt ccggagcggg tatgtgcgcc
     9961 gtaccgcggc aacagcaggg ccgactgaga ggggacactc gtgcctgctt tctcctacag
    10021 caccgcagcg acacagacag cagttccgcc ggcactcgca cttccggtga tcgagaagga
    10081 gtttcctcgg caactccatc cctattggcc gacactccag gagacgacac gtgcatggct
    10141 cctgaaaatg gggctgatgc cggccgacaa ggtcgaacgg tacgccgacg ggctgtgcta
    10201 caccgatctg atggccgggt actacctcgg cgccccggtg gaagtgctcc aggcaattgc
    10261 cgactacagc gcgtggttct tcgtctggga cgaccgccac gaccgtgacg tcgtgcaccg
    10321 cagggacgcg gcgtgggcac ggctgcggga ctgcctccac gcggcgctcg acgccccgtg
    10381 gcgccatctg caacacgagg acgccctggt agcggccttc gcggacagca tgatccggct
    10441 ttactcgttc ctgggcgaga gctggaacgc ccgcttcgcc gcacacttcc acgaagtgat
    10501 cgaggcgtac gacagcgagt accgcaaccg gaccacgggc cgcattccgg cggtcaccga
    10561 gtacctggaa ctgcgccgcc tcaccttcgc ccactggatc tggctcgatc tcctggagcc
    10621 cgccgcccac cacgaaatac cccggtcggt actggagaat cccgcctacc gcaaggccgg
    10681 gctcgcctgc caggatttcg ccgcctggta caacgacctc tgctcattgc ccaaggaact
    10741 cgcgggcgat gaataccaca acctcgggat cagcctcatc aaacatgagg gaatgaccct
    10801 ggaggacgcg gtcacggaag tacgccgaag ggtaaacgga tgcatatccg aattcctggc
    10861 cgccgaacag gaagtagccg ttctcatcgg tgaactccgg gacggcacat ggcgcggcga
    10921 accactcgcg gacgccgtgg cgctcaacat ctccaatatg cggaactggt tcagttccgt
    10981 gtactggttc caccacgagt ccggtcgcta ccaggtcgac agctgggccg accggtccac
    11041 gcccccctac atcagcgacc agggcgaacg gcccggatcg gcgggaatcc gatgaccggt
    11101 ggaccgaccc cccgaacagc ggggaccgac ggccggaacg cgcctccgcc gccgtacgcc
    11161 aagggcggcg cccccctgct gggacacgcc tggaacctgg tgcgcgaccc gctccgcttc
    11221 gtcgccggac tgcgcgacag cggggacgtg gtgcggctgc ggctcggccc cgggacggcg
    11281 tacgccgtgt gcgccccgga actcgtggcc gctctcctca agagcccgga ctacgaggtc
    11341 ggcggaccgc tctgggacac catggaactc ctcatcggca agggcgtcgc caccagcaac
    11401 ggcccgctgc accggcgcca gcggcgcatg atccagcccg cgttccggcc cgagcggatc
    11461 gccgcccacg cgcccgtcat ggcggaggag gccgccgcga tggccgaccg gtggagcccc
    11521 ggcgccaccg tcgacatcgg cgacgaggtg ttccgcacgg cggtccgtat cgtcacccgc
    11581 tcgctgctcc acgtcgactc gatcgacgag cgggtggacc ggctcggcgg ctcgctgcac
    11641 accgtcttcg ggggcctgta ccggcggatg atcctctccg ccggaccgtt ctggaaactg
    11701 cccctcccgg cgcaccgtcg attcgaggtc gcattggccg atctgcatcg gttggtggac
    11761 gagatcgtca gggaacgccg tatgtccgga acggaccgcg gggacctgct ctcggcattg
    11821 ctccgggcaa aggacgacaa tggtgaaacg ctcaacgaac aagaggtaca cgaccagacg
    11881 gtctccctcc tcgtggcggg cgcggaaaac gttgcctcga cgctgacgtg gacgttccag
    11941 ttgctcgcgg agcacccgga ggaggaaaag cggctccgcg cggaggtgct gtccgtgaca
    12001 ggtggccggc cggtgacatt cggtgacctg ccgaagctcg ggcacacccg gaatgtcatc
    12061 accgaggcga tgcgggttcg gcccgccgta tggattctga cccgccgggc ggtggccgat
    12121 tccgtactgg gcggatatcg cattccggcc ggggcggaca tcgtctacag cccgtacgcg
    12181 atgcagcggg acccccgggc gttcgcccgg caactggagt tcgaccccga ccgctggcag
    12241 cccggaacgc aggcggaccg gggcggaccg gcgatgatgc cgttcggcac cggcaaccgc
    12301 aaatgccccg gggaccactt cagcatcgtc gagatggcga tcgtgctggc caccgtcgtg
    12361 ccccggtgga gcctgtcccg gctgcgggag accgacaccg ccccgcggat cgggatcacg
    12421 ctcaagccgc gccggcccag gctccgggcc gtgccggtgg catagtccgg acgctcgttc
    12481 ctgtacgcgc cccccgttcc gggcggtccc gggaggcggg gcgcgtgatc agggagccgt
    12541 ctccaggggg cgcgggcccc tgaacgtcct gcggtacgcg ttcggggtgg tgccgaggac
    12601 ccgcaggaag tggtggcgca gggtcgcgcc gttgccgaaa ccggtgcggc ccgcgacgga
    12661 gtcgaccgtc tcgtccgtcc cctccaggag ctgctgcgcc agcagcaccc gctggcgcag
    12721 cagccagcgg tacggggtcg tccccgtctc ctgctggaac cgccgggcga acgtccgggg
    12781 cgacatatgc gcccggtccg ccagctcctc gaccgtgacc gcgcggtcga ggtggcgctc
    12841 catccacacc agcacctcac cgaccgtgtc gcaccgggtc gtcggcaccg ggcgctcgac
    12901 gtactgcgcc tggccgccgt cccggtgcgg gggcaccacc atccggcggg cgagcgcgtt
    12961 ggcgacctcc gaaccgtgct cctggcggat gatgtgcaga caggagtcga taccggcggc
    13021 cgaccccgcc gaggtgatca ccgggtgctc gtccacgtac agcatgtcgc gctccacccg
    13081 ggcccggggg aagcggatcg cgagctcgtc cgcgtgccgc cagtggcccg cgcagcggcg
    13141 gccgtcgagc agcccggccg cgcccagcac gaagacaccc gaacagacgg agagcacccg
    13201 ggtcccccgg gcggtggcgc ggcgcagggc gtcgagcagc ggctcgggga actcccggct
    13261 gccgtagtcc tcacccgcgg ggatcgcgat cagatcggcc tcctccagcc gctccagacc
    13321 gtgctccagc cgcaccgaga agcccgcgtg ggtggacagc tcgggaccct ccgccgagac
    13381 caccgcgaaa tcgtagaccg gcaggccctg ttcgctgcgg tccagcccga agacctcgca
    13441 gacgacgccc agttcgaagg gatgcacccc gtccagcagc accaccgcga cgttgttcag
    13501 catgccgtca gtgtgctgcc gtgatggcag gaagtcgagg gtgcatgaca cttctgccac
    13561 tgccgcgcgg cgggcgcgcg ggccacagtg gaggacatga acacactcct ggactactcg
    13621 gtcgtcaccc tcgtcctcgc cctgctgctg ggccccgtca cccccggcta cctgcgggaa
    13681 cgccgtatcg accgggaact gagagacgcc ggacgcggcc ggcccggcca ccccgagggg
    13741 cgaccgggcc ggtccttgga cctcgccgcg tgaagccggc cggcttcggc gggcctagaa
    13801 ctcgtcgtcg aagccgacct tgccctccac cgccacctgg tacgcggacg gacggcgctc
    13861 gaagaagttc gtcagctcct ggacaccctg gagctccatg aacgcgaacg ggttctgcga
    13921 gccgtacacc ggggcgaagc ccagccgctc cagccgctgg tcggccacgc actccaggta
    13981 ctggcgcatc gactcggtgt tcatccccgg cagcccctcg ccgcacaggt cacgggcgaa
    14041 ctggagctcc gcctcgacgg cctcccggag catgtcggtg acctgctcct ggagcttgtc
    14101 gtcgaacagc tccggctcct ccttgcggac cgtgtcgacg acctcgaagg cgaagctcat
    14161 atgcatcgtc tcgtcacgga acacccagtt ggtgcccgtc gcgagaccgt gcagcagacc
    14221 gcgcgagcgc agccagtaca cataggcgaa cgccccgtag aagaacaggc cctcgataca
    14281 ggcggcgaag cagatcaggt tcagcacgaa ccgacgccgg tcggcctgcg tctccagctg
    14341 gtcgagcttc tcgaccgagt ccatccactt gaagcagaat tcggccttct cccggatgga
    14401 ggggatgttc tccaccgcgg cgaacgcggc ggtgcggtcc tccgggtcgg gcagataggt
    14461 gtccagcagc gtcagataga actggacgtg cacggcctcc tcgaacagct gacgcgacag
    14521 gtacagccgg gcctcggggg agttgatgtg cttgtacagc gtcaggacca ggttgttcgc
    14581 gacgatcgag tcgcccgtcg cgaagaacgc caccagccgg ccgatcagat gctgctcggc
    14641 gggcgacagc ttcgcgaggt ccgcgacgtc cgagtggagg tcgacctcct cgacggtcca
    14701 ggtgttcttg atcgcgtccc ggtagcgctc gtagaagtcg gggtagcgca tcgggcgcag
    14761 ggtcagctcg aagcccgggt ccagcagatt gcgctcccgc ggggccgcgg cggcgggttc
    14821 ggtgggggtg gtcgtcatta ctggcatgcc tcgcaggact cggggttctc cagggagcag
    14881 gcgatcgcgt ccgcgtcggg cgcggcctgc tgcacgggga tggtggtggg ggcgggccgc
    14941 tcggcggcgg cggacgaacc ggccgcgcgg gcgatccggg tcgccggacg cgaccgcagg
    15001 tagtacgtgg tcttcaggcc cgacttccag gcgtacgcgt acatcgagct gagcttgccg
    15061 atggtcggcg tctccaggaa caggttcagc gactgcgact ggtcgaggaa cggggtccgc
    15121 gcggcggcca tgtcgatcag accgcgctgc gggatctccc acgccgtgcg gtacagcgcc
    15181 cggacctcct cgggaatcca gcggaagtcc tgcaccgaac cgctggactc acgcagcgcc
    15241 tcacgggtgc gcgcgtccca gacgcccagc tccttgagct cgttcaccag gtacgagttg
    15301 acctggagga actcaccgct cagcgtctcg cgcttgaaca ggttggacac ctgcggctcg
    15361 atgcactcgt agaccccggc gatcgacgcg atggtcgcgg tcggcgcgat ggccagcagc
    15421 agcgagttgc gcagccccgt gacggcgatc cgggcacgca gcgcgtccca gcgctcgggc
    15481 cagtgcggct cgaccccgta gtggtcgggg tgcagcaccc cgcgggcggt acgggtcttg
    15541 tcccaggccg ggagcgggcc gttgcgctcg gcgagcgagg cggacgcctc gtacgcggcg
    15601 agcatgatcc gctcggcgat ccgggtggac agggcgcgcg cctcggggga gtcgaagggc
    15661 agccgcagct tgaagaagac gtcctggaga cccatcgcgc ccaggcccac cggccgccag
    15721 cgggagttgg agcggcccgc ctgctcggtc gggtagaagt tgatgtccac gacccggtcg
    15781 aggaaggtca cggccgtgcg gaccgtggag tccagccgct cccagtcgat gccgtcgtcg
    15841 ccctcaccgg tgacgaacgc gccgaggttg accgagccga ggttgcacac ggccgtctcg
    15901 ccgtcgtcgg tgacctccag gatctcggtg cagagattcg aggagtggac ggtgtgaccg
    15961 ggctcggcgg tctggttggc ggtgcggttc gcggcgtcct tgaaggtcat ccagccgttg
    16021 ccggtctggg cgagggtccg catcatccgc ccgtacaggt cccgcgcggg gatcgtcttg
    16081 cgggccagcc cggcggcctc ggcccggcgg tacgcggcgt cgaactcgtc gccccacagg
    16141 tccaccagct cgggcacgtc cgagggggag aacagcgacc aggtgccgtc ctggtcgacc
    16201 cggcgcatga actcgtcggg gatccagtgc gcgaggttca ggttgtgggt gcgccgcgcg
    16261 tcctcgccgg tgttgtcccg cagctccagg aactcctcga tgtcggagtg ccaggtctcc
    16321 aggtagaccg cggcggcgcc cttgcgccgg ccgccctggt tgaccgccgc gacggaggcg
    16381 tcgagcgtct tcaggaacgg gacgatgccg ttggagtggc cgttggtgcc ccggatcagc
    16441 gagccgcgcg aacggatgcg ggagtaggac agcccgatgc cgccggcgtg cttggagagc
    16501 cgggcgacct ggtggtagcg gtcgtagatg gagtccagct cgtcctgcgg ggagtcgagg
    16561 aggtagcagg acgacatctg cgggtggcgg gtgcccgagt tgaacagggt gggcgacgag
    16621 ggcaggtagt cgagccggct catcagccgg tagagcgccg cgacctcgtc cagcgcgcgt
    16681 acggagtcgt cctcggcgag accggaggcg acccggagca ggaagtgctg cggggtctcg
    16741 acgaccttgc gggtgatcgg gtggcgcagc agatagcggc tgtgcagggt gcgcagcccg
    16801 aagtagccga agcggtcgtc ggcggtggtg tcgatgagcg cgtcgagacg gtcggagtac
    16861 ttcgtcacga acgcggcggt gcggtccgcg atcaggccct cgcggtgccc ggtggcgacg
    16921 gacccggaga aggcgagcac cccctgggag gcggcctcgg cggcgatgct gacggtcagc
    16981 agccgggcgg cgagccggga gtaggcgggg tcctcggaga tgagtccggc ggcggcctcg
    17041 gtggcgagtt cacgcagctc gctctcgtcg gcgcgggcgg accggccgcg cagcgccgcg
    17101 gcggcgaccc ggccggggtc ggcgtcgggg aggtcggccg tcaggtcggt cagcgtccgc
    17161 agcagcgcgg ccccggggcc gtcgctcggt cgggtctgct ggtcctgggc ggtcgtcgca
    17221 ggagcctggc cgacaactga tgccggatcg gctggcgcga tggtcacgtg aagctctccc
    17281 tcgctcggca cgggactggc gagggggcgg gcgggcacgc gggcgcgccg ccccgaaggc
    17341 ggtacgccgc gtccaccggc ccagtcctcg aagcccggac gtctcatctc cacccggacc
    17401 ggtcggaacg ggtgcgccac tgtcaggtca tcggactcac gggtgcgcga aagcgcacca
    17461 agtacaccgt tgcgggacag ttccggattc gcaccggatt cccctgaggt ggcggcgagc
    17521 atgagcatac atcttgtgtt gccgtgcgag agggaggccc acatgttgtg tctgtgtggc
    17581 gcggggcacg ttgccgggtg gcgccgggag gggccttggc ggggcgcgga acggcgccgt
    17641 gggaggcgtg aattcggggc gtcccggggg cgtggaaggc gtctggaggg gccgtcgggg
    17701 acggccgggc atccggcggc ggaggtgtcg cgcggcgcgg cgcgaagggc cgtgcgcggc
    17761 gtcggcggcg aagcggggcg cggacgcccg gggcgtgtcc gtcgtcacgc tccgtggtgg
    17821 ctgaagatga tccatggagc ggagcccgga aaaatgccat tggtccagac aactcgcctt
    17881 gtccggccct gcggaggcgt tctacgactt tcgtcggcgc cccgtccacg tggctgggtg
    17941 aggttcctgg ggcaggaggg ggatcggtgt cgcgtccgta ccgggacggc tggttccccc
    18001 cgcgaagtgg ggtggtttcc cccggcgggc ccgtttcggg gcccgccggg gaaaggaggg
    18061 gacgctcagt ccgtcggccg cttcagacgg gccacgaact tgtaccggtc gccccggtag
    18121 accgagcgca cccactccac cggccggccg ccgccgtcca gggaatggcg cgagagcatc
    18181 agcatcggca gtcccacgtc ggtgccgagc agtccggcct cgcgcggggt ggccagtgag
    18241 gtctcgatgg tctcctcggc ctcggccaga tgcacgtcgt acacctcgcc cagcgcggtg
    18301 tagagagagg tgtacttgac cagggaacgc cgcagcgccg ggaagcgctt ggcggacagg
    18361 tgcgtggtct cgatcgccat cggctcgccg ctcgccagcc gcagccgctc gattctgagg
    18421 acccgccccc cggtcgctat gtcgagcagc cccgcaagcg tgtcatctgc ggtgatgtac
    18481 ccgatgtcga gaagctgcga ggtcggctcc aggccctgcg cgcgcatgtc ctcggtgtac
    18541 gaggtgagct ggagcgcctg ggagaccttc ggcttcgcga cgaaggtccc cttgccctgg
    18601 atgcgttcga gccgcccctc gaccaccagt tcctggagtg cctggcgtac cgtggtccgc
    18661 gaggtgtcga actctgccgc cagggtccgt tccggtggca ccggtgttcc cggtgtcagc
    18721 gtctcggtca tgtcgagcag atgcttcttc agccggtagt acttcggtac gcgtgcggtg
    18781 cggcctgttg tggccgtctc cgccgtggcg gaagtacccg cccggctcac ctcgctcgcc
    18841 atcgtccgcc ttcccggctc tggtgctgtt gccgccaccg gctcctccgt ctgtagcggc
    18901 tcacacatcg tggcacggtg tgcccggcgt gagccgtgcc ccctcaggtg tcggtccgat
    18961 aacggacgtg acagcccttc ttatacaccc ttgacacccc taaaggtcta ggccaagctc
    19021 cagctactgg tctacaccat taaaggccag gtcccagttc ccacgagcag tttcgcgctg
    19081 tagtcattcg ctgtgggtgt ggggggtagg catcctgagg agggtgacgt gaagcggaag
    19141 ctcattgcgg ccattggtgt cgcgggcatg ttgttctctg tcgctgcgtg cggcgacagc
    19201 gacagcgggg acaagaagga gtccaagggt acggacacca aggggaagac cctggtcgtc
    19261 tggtccatgg acggctccac gccggacccc tggaagaagg ccgtggcggc cgacttcgag
    19321 aagaagaccg gctcgaagat caagtgggag tcccaggtct ggaacggtat ccagcagaag
    19381 atcaccaccg ctctctccga gtccagcccg ccggacgtca tcgagatcgg caacacccag
    19441 acccccgcct acgcggcgac cgagggtctc gcggagctcg gcgacctcaa gaccgagatc
    19501 ggcggcgagt ggaccgaggc gctgaacaag tcctcgatct acaacgacaa gcagtacgcg
    19561 gtgccgtggt acttcgccaa ccgtgtcgtc ctctacaaca agaagatctg ggccgaggcc
    19621 ggtctgaagg acacgcccaa gacgcgtgac gacttcttca aggcgctcga caccatcaag
    19681 gagaagacca aggccgagcc gctgtacatg gccggtcaga actggtactt cctcgatggc
    19741 ctgatcatcg gcaagggcgc cgacctggtg aagaaggaag gcgacaagta cgtctccaac
    19801 ctgtccgacc cgaaggtcgg cgaggcgatg gagctgtaca agaagtacgc ctcctactcc
    19861 tcggccccca aggacaagga cgaggccacc ccgcagcagg ccgacgtctt cgcgaacggc
    19921 aagaccgcca tgttcatcgg caacgcttcc gaggccacca tcgcggtcaa ggccaacgcc
    19981 aagatcgaga aggacatcgg ctacttcacc atcccgggtg agtcggccga gaagcccgag
    20041 agcgtcttcc tgggcggctc caacctcgcc gtgccgctgc gcagcaagaa ccaggagctc
    20101 gccaaggagt tcctgaagat cgcgctcgcc gatgagcacc agatcgagtt ctccaagctg
    20161 atgggcttca ccccgaacaa ggcgtcgctc ctgcccaagg tcgcgggcag caacgccggc
    20221 ctcgacgccg ccgccccggc cgccgcgttc ggtggcacca ccccgctgat ccccgagtgg
    20281 gccgcggtcg agaacgtccc gaacccgatc aaggactaca tgacggcggt cctgaacggt
    20341 aagtcgcacg ccgacgcggc caaggacgcg gacgcggaga tcaacaagcg cctcgcacag
    20401 ggcagctgac ccgagtaccc ccgcgcccgg ggggcggcgg gccggacctt cacacaggca
    20461 ccccagccgg ggtgacctga ggaaagaccg gtccgccgcc cccggggcgc accggtgtgc
    20521 gcctcggggg cgcccacccg cgcatcgaaa cgtacggcca cggaagagac ggcgacgatg
    20581 tcagtgcaga ccgaacaagc ggatgcggac ggggtgtccg tccggaaggg cgaggcgcca
    20641 ccgcctcgcg gcgcggggag cgccaccaag aacggcggag gcggtcgcag atcgccacgg
    20701 gcccgtggct cgttcgcccc gtacgcactg ctgctgccgg cgacgatcgt caccatcgtg
    20761 ctgctcggct ggcccctggt gaagaacggc atgctgtcgt tccagaacct gaaccccaag
    20821 cagctgatcc tccacctcac cgagtggaac ggggtcgaga actacaagga gacgctgacc
    20881 aacgaggact tctggcgggt cgtactccgc tcgttcctct tcaccacggt caacgtcgtc
    20941 ctgatcatgg tgctcggcac cctgatcggt ctgctgctcg cgcgcctcgg ccagcggatg
    21001 cgggtcaccc tgctgatcgg cctcgtgctc gcctgggcca tgccgatcat cgcggccacc
    21061 acggtcttcc agtggctgtt cgcccagcgg ttcgg
//
