LOCUS       NZ_LFBV01000001        30809 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces uncialis strain DCA2648 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_LFBV01000001
VERSION     NZ_LFBV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces uncialis
  ORGANISM  Streptomyces uncialis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2018837)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Cloning and characterization of the uncialamcin biosynthetic gene
            cluster
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2018837)
  AUTHORS   Yan,X., Huang,T., Ge,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2015) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33410, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-MAY-2015
            Assembly Method                   :: CLC Genomics Workbench v. 8.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905345.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:03:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,456
            CDSs (total)                      :: 7,371
            Genes (coding)                    :: 7,214
            CDSs (with protein)               :: 7,214
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 5 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 42 of 157
            Pseudo Genes (incomplete)         :: 143 of 157
            Pseudo Genes (internal stop)      :: 7 of 157
            Pseudo Genes (multiple problems)  :: 33 of 157
            CRISPR Arrays                     :: 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:56:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 30809
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LFBV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..30809
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NAPAA"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(AMP-binding and TIGR02353)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..30809
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="NAPAA"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..30809
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11618:15809](+)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11619..15809
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     gene            180..1661
                     /locus_tag="AB852_RS39445"
     CDS             180..1661
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS39445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="HNH endonuclease"
                     /protein_id="WP_073782292.1"
                     /transl_table=11
                     /translation="MSEIQQNPMTAQSSRSEATQNAARPVRPEVDAKPKGIALYHDMRV
                     EEDFAKCATRLFSILKKAAATSPGAPRYVYLDIQGHRNAAGGYDADALEIIREFLLGFL
                     CPYLTEISTPLYHVRNPESQREDIPDVLNVRDPYGEHSYDHRELRVRNRDSSPDQRRSR
                     PPVRAIADYLGLDEPICLICWQAPVERAHVVPESLGGSNDVRNFALLCPRHHREAPDVA
                     DAEAFWSWVDYACERDGHMKWEGVDPEILAKAERVGLQIETRGSVRKSLRHFDRVRDEL
                     MRHYGWCPEDFAGGYHWGALMEEFHTVMDSATSTHFNVPKKASTEAWAFEVARRRLRDG
                     VAEREADNHESAASGRLSIELAEWTMRKSPESHGAQNLVDAARRADIAIEAAALVRDII
                     SSAGVSSAEEVLRGIMEEVTDRTAQFDRLNDELMGQASCRYCGHAIARIGDTPWRHSAA
                     APMSRGCRAASFDRDGNWDDSLDRAWVASPPKSYR"
     gene            complement(1907..2209)
                     /locus_tag="AB852_RS00010"
                     /old_locus_tag="AB852_00010"
     CDS             complement(1907..2209)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AB852_RS00010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AB852_00010"
                     /product="hypothetical protein"
                     /protein_id="WP_073782294.1"
                     /transl_table=11
                     /translation="MPRRPSATPWPALLVPAKAVNLYLAYAVVTTTPGGAWDENTLTGI
                     ETACSLLLLTAALTESLNYAALRHRALPHRWLILATCLPTVACVRWGRIVQRYPG"
     gene            complement(2342..3100)
                     /locus_tag="AB852_RS00015"
                     /old_locus_tag="AB852_00015"
     CDS             complement(2342..3100)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174229.1"
                     /locus_tag="AB852_RS00015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00015"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_073782296.1"
                     /transl_table=11
                     /translation="MALNQASGEDGTRLARHDIAAGAVAQVLLLALLAGTVGLGPAGRL
                     TGLVFAVGTWVLLIRALRRARPGPFGPANRVTLARATLVGGVTALVADSLDGPPRVAAL
                     AALAGVALILDAVDGLVARRTGTVSELGARFDMEVDAFLILVLSVYVSARLGVWVLLIG
                     LMRYGFVAAARVLPWLNAPLTPSTARKSVAALQGVALLAAATYLPRPLTLPVILLALTT
                     LTWSFGRDIHTLHRTRPLRDPTPRESATVG"
     gene            3378..4313
                     /locus_tag="AB852_RS00020"
                     /old_locus_tag="AB852_00020"
     CDS             3378..4313
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059564.1"
                     /locus_tag="AB852_RS00020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00020"
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="WP_245876541.1"
                     /transl_table=11
                     /translation="MPLPEPGDGDVVVRSLYSGVSRGTETLVLRGGVPRSQHTAMRAPF
                     QEGDFPAPVKYGYLNVGVVEGGCAALLGRTVFCLYPHQTRYVVPATAVTPVPGTVPAAR
                     AILAGTMETAVNALWDAAPLVGDRIAVVGAGMVGACVAALLVRFPGVRVQLVDADPAKA
                     AVADALGVRFAAPDDALGGCDLVVHASATEAGLARSLELLAPEGTVLELSWYGDRKVSL
                     PLGEAFHSGRLVVRASQVGAVSPARRSRRDFRDRLALALDLLADPALDALITGESAFDD
                     LPRDMARIAAGELPGLCHRVVYGSEGRWAP"
     misc_feature    complement(4558..4572)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     gene            4641..5039
                     /locus_tag="AB852_RS00025"
                     /old_locus_tag="AB852_00025"
     CDS             4641..5039
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTPS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431583.1"
                     /locus_tag="AB852_RS00025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00025"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_073782298.1"
                     /sec_met_domain="PTPS (E-value: 4.5e-22, bitscore: 75.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSITVRDHLMVAHSFRGEVFGPAQRLHGATFLVDATFRRAELDA
                     DNIVVDIGLATRELGTVVAALTYRNLDDEPDFTGVNTSTEFLAKVIADRLADRAASGAL
                     GEGARGLAGITVTLHESHIAWASYERAL"
     misc_feature    complement(4672..4687)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.63"
                     /tool="antismash"
     gene            5279..6361
                     /locus_tag="AB852_RS00030"
                     /old_locus_tag="AB852_00030"
     CDS             5279..6361
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139787.1"
                     /locus_tag="AB852_RS00030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00030"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_073785097.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.4e-28,
                     bitscore: 96.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHFVMPGGVDDPAAPSGGNTYDRRVSLDLSGFGWDVRAHTVDGDW
                     PRPDAVATARLAHTLAALPDGAVVLLDGIVACPAPETVVAEAERLRLAVLVHLPLADES
                     GLDEATAAELDALERTTLRAAAAVVATSDWAAQRLVSHHGLASRRVHVAAPGTDIAPLA
                     TGTDGISRLLCVGSLTPRKGQHRLVRALATVADLPWSCVLVGGLDQDPGYVSRLRALVD
                     ELGLTGRVRIAGPQVGAELNASYARADLMVLASDSETYGMAVTEALARGIPVLVTEIGG
                     LPEAVGRAPDGSVPGVLLPDTDPAALGTAVRRWFDEHDERQRLKAAARSRRTSLDGWAT
                     TARSLSGVLEQLRRDTWSAV"
     gene            6358..7218
                     /locus_tag="AB852_RS00035"
                     /old_locus_tag="AB852_00035"
     CDS             6358..7218
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656603.1"
                     /locus_tag="AB852_RS00035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00035"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_073782300.1"
                     /transl_table=11
                     /translation="MTATADPTRFTPDWLALREPADAAARSAALLGPLRPGLVAHARSG
                     TPLVVHDLGCGAGSMARWLVPRLPMAQHWVLHDHDPDLARLAAERTPRSAADGSPVTVA
                     TRGGDVSRLTASALAGASLMTMSAFLDIVTSDTVDRLAAACAGAGCPALLTLSVVGRVE
                     LTPADPFDADVARAFNAHQRRSGLLGPGAVEAATTAFTRHGMTVRVHESPWRLGPAHAA
                     LTAEWLRGWTGAARDQRPDLAARLDAYRARRLAACATGDLRVTVHHADVLALPRGSRTP
                     HAPTP"
     gene            7202..>8485
                     /locus_tag="AB852_RS00040"
                     /old_locus_tag="AB852_00040"
                     /pseudo=""
     CDS             7202..>8485
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007495708.1"
                     /locus_tag="AB852_RS00040"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00040"
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPPPDPRTTPASPPPAPALSARPASTCTGTDTGTGTGTDDAGTD
                     TARSPHGGSTPPVDTPPGHGSDGDAKSGQGSDGNAPPGHAPPNPALHGHTPKRDPPGRL
                     RTWLPPLAGAAILALLLSRLGTSAVTEGLTRVTPDAVFAALALGAFTTVLSAWRWHLVA
                     RALGLGLPLGRAVADYYGALFLNSVLPGGIVGDVDRAVRHGRGSGELGRGVRAVVLERT
                     AGQLVLLAVAAVVLTTFPSPAADHARRALTGPWTAAVLAVGCGATALVVALRARAAAGA
                     DARPAAPAAPAAPAGTHGAVRATSAAPATPATRARADRRALYGRRTAPAVLGVSAAVLA
                     GHLVLFWLAARVSGVTAPFAVLLPLMVLALLAMSVPLNIGGWGPREGVTAWAFGAAGLG
                     AAQGLTVSVLYGVLAVVAALPGALVLPAR"
     gene            complement(8522..9481)
                     /locus_tag="AB852_RS40325"
                     /old_locus_tag="AB852_00045"
     CDS             complement(8522..9481)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /locus_tag="AB852_RS40325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00045"
                     /product="RibD family protein"
                     /protein_id="WP_079184184.1"
                     /transl_table=11
                     /translation="MNHPLSPTPGNDPADTPGNDAGPLADGRAHSPSAEAPDTRSHTPE
                     SLPPAAELSGDEAWRRLLDVRAPADARAAGLVAGPDGGWRWAGPASTEAADLADRYLPL
                     CLAGPRVTFAQLGQSLDGFIATRTGDADYVTGEEDRRHLHRLRALADAVLVGAGTAVAD
                     DPQLTVRACAGAHPVRVVLDPRGRVPADRRVFTDGSAPTLWLVGPGSGPGRPVADGVTV
                     LRLPDDDAFTPRRLVATLAHRGLGRVLVEGGGVTVSRFLHGGALRRLYVTVAPVLLGDG
                     VPGLRFDGPDVMREARRPPLRRARLGEDTLFELDLTDA"
     gene            complement(9478..10242)
                     /locus_tag="AB852_RS00050"
                     /old_locus_tag="AB852_00050"
     CDS             complement(9478..10242)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656601.1"
                     /locus_tag="AB852_RS00050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00050"
                     /product="creatininase family protein"
                     /protein_id="WP_073782306.1"
                     /transl_table=11
                     /translation="MKEPAPDRTAALLLPTETTTEVSARDADVAVLPIGSFEQHGPCLP
                     LVTDTVVACALSRRIAAAHRVLSLPPITVSCSHEHADWAGTVSISAATLYHMVRDIADS
                     LRRSGIRSLVLVNGHGGNYVLRNVVQESAGWGIRMALFPESADWKAARETAGISTSAHD
                     DMHAGEIETSILLHTHPELLRPGHESTDRSAGDRRHLLTLGMREYTTTGVLGRPSRATA
                     EKGAALLDSLTESFGAYHALLRGPGAQDGDDS"
     misc_feature    complement(10315..10325)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    10419..10432
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.85"
                     /tool="antismash"
     misc_feature    10424..10433
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     gene            10482..11201
                     /gene="ribA"
                     /locus_tag="AB852_RS00055"
                     /old_locus_tag="AB852_00055"
     CDS             10482..11201
                     /EC_number="3.5.4.25"
                     /GO_function="GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ribA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191545.1"
                     /locus_tag="AB852_RS00055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00055"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_099279933.1"
                     /transl_table=11
                     /translation="MTAAITENGGVGGAVAGELTGDVADAGSGRSVVPVNGVERVVRVR
                     LSTGHGEFLAVGYRDHALGQEQMLLVHGDIEGERVLTRLHSECLTGDAFGSRHCECGGQ
                     LDAALCAITSEGSGVLVYLRGHEGRGIGLLAKLQAMRLQADGMDTVEANIALGLPVDAR
                     DYTVAADMLHDLGVRSVRLLSNNPRKGEALLRHGIKVAERVPLLIPPSEENLAYQRAKR
                     ERLDHDLPHLDAITEHL"
     gene            11619..15809
                     /locus_tag="AB852_RS00060"
                     /old_locus_tag="AB852_00060"
     CDS             11619..15809
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (47-514). E-value: 4.5e-78.
                     Score: 254.6. Matches aSDomain:
                     nrpspksdomains_AB852_RS00060_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (619-687). E-value: 1.5e-17. Score:
                     55.5. Matches aSDomain: nrpspksdomains_AB852_RS00060_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (705-1391). E-value: 1.2e-253.
                     Score: 835.3. Matches aSDomain:
                     nrpspksdomains_AB852_RS00060_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532753.1"
                     /locus_tag="AB852_RS00060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00060"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_079184185.1"
                     /sec_met_domain="AMP-binding (E-value: 6.6e-78, bitscore:
                     258.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.2e-09, bitscore:
                     33.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 3.5e-252, bitscore:
                     835.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTTPATAPEGDDLAPPPPGTAPGPPAPAVLTAGPAAPPRTLVD
                     ILDASVRRYPGEPALDDGTTRLTYRALATEVDTLRRRLAHSGVRPGARVGVRVPSGTND
                     LYVAILAVLAAGAAYVPVDAEDPDERAELVFGEAGVHAVIGAGHRIDPPPAARTAKSSK
                     PSPTRTATAPAATAVTSTATTTVTTAARTGSAARTPTAASATATGPGSPVGTSGDRAAT
                     PRGPSVTHGNPATSEGHADAPTPGTRPVPNPGGTRPTPADDAWIIFTSGSTGTPKGVAV
                     THRGAAAFVDAEATLFLTDDPIGPGDRVMAGLSVAFDASCEEMWLAWRHGACLVPVPRA
                     QVRSGADLGPWLVEQEISVVSTVPTLAALWEPDALADVRLLIFGGEACPPELAQRLVTE
                     GREVWNTYGPTEATVVACASLLTGAEPIRIGLPLNGWDLAVVDDAGLPVPMGATGQLVI
                     GGAGLARYLDPVKDAEKYAPLDALGWPRAYRSGDLVRAEPEGLVFLGRADEQIKLGGRR
                     IELGEVDAALQALPGVAGAAAAVRTARGGNQLLVGYLVTQDGWDHPAAVARLRAELPAA
                     LVPLLAPVAELPTRTSGKVDRDALPWPLPGLTTGGPAEQLYGTEAWLAEQWSEILGVPV
                     TGADDDFFAIGGNSLAAAQLTTRLRARHPGAAVLDIYQQPVLRKLARRLEKSTQDDTTT
                     RTVTPVPRRAQALQTLLLLPLFTLAGLRWTVGVLALGNVLHLFGAYPWAPTASWWLVAA
                     GAAVFFSPPGRLALAAGGARLLLRGVGPGRYPRGGAVHLRLWTAERLAELVGATALTGA
                     WLERYARALGARIGPDVDLHSLPPVTGLLRLGRGCAVESEVDLSGHWLDGDRLHIGAVR
                     VGAGAVVGTRSLLFPGARVGKRAEVAPGSAVTGQIPTGQRWAGAPAVKLGKAKRDWPGE
                     RPPRSAGWRAMYGATGLGLLALPLLAAVPALLVAAVFVAPGAGPADALRGALVAVLPAA
                     LAFGFGYALLLLTAVRLLSLGLRTGTHPAHSRTGWQAWTVTQLMDLSRETLFPLYAGLI
                     TPVWLRLLGMRVGRGAEVSTVLALPSLTTVGDGAFLADDTLTAPFELGGGWLRIGRAEI
                     GRRAFLGNSGMTAPGRSVPDGGLVGVLSATPKKAKKGSSYLGLPPVRLPRAAADADHSR
                     TYEPPARLLWARGLVELCRLVPVFCSTALAVLTVLALSALARTLGPGAAALLSGAVLLT
                     AGLTAALVAVLAKWLLVGRHRTGEHPLWSGFVWRNELADTFVEVLAVPWFAGAVPGTPL
                     LTLWLRALGARIGRGVWCESHWLPETDLVTLGTGATVNRGSVLQTHLFHDRILRTDTVD
                     LREGATLGPNGIVLPGSTVGARSTLGPASLVMAGESVPAETRWLGNPIEAWRS"
     CDS_motif       11706..11738
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00060_0001"
                     /evalue="1.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="AB852_RS00060"
                     /protein_end="40"
                     /protein_start="29"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="AVLTAGPAAPP"
     aSDomain        11760..13160
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AB852_RS00060_AMP-binding.1"
                     /evalue="4.50E-78"
                     /label="AB852_RS00060_AMP-binding.1"
                     /locus_tag="AB852_RS00060"
                     /protein_end="514"
                     /protein_start="47"
                     /score="254.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DASVRRYPGEPALDDGTTRLTYRALATEVDTLRRRLAHSGVRPGA
                     RVGVRVPSGTNDLYVAILAVLAAGAAYVPVDAEDPDERAELVFGEAGVHAVIGAGHRID
                     PPPAARTAKSSKPSPTRTATAPAATAVTSTATTTVTTAARTGSAARTPTAASATATGPG
                     SPVGTSGDRAATPRGPSVTHGNPATSEGHADAPTPGTRPVPNPGGTRPTPADDAWIIFT
                     SGSTGTPKGVAVTHRGAAAFVDAEATLFLTDDPIGPGDRVMAGLSVAFDASCEEMWLAW
                     RHGACLVPVPRAQVRSGADLGPWLVEQEISVVSTVPTLAALWEPDALADVRLLIFGGEA
                     CPPELAQRLVTEGREVWNTYGPTEATVVACASLLTGAEPIRIGLPLNGWDLAVVDDAGL
                     PVPMGATGQLVIGGAGLARYLDPVKDAEKYAPLDALGWPRAYRSGDLVRAEPEGLVFLG
                     RADEQIKLG"
     aSModule        11760..15791
                     /complete
                     /domains="nrpspksdomains_AB852_RS00060_AMP-binding.1"
                     /domains="nrpspksdomains_AB852_RS00060_PCP.1"
                     /domains="nrpspksdomains_AB852_RS00060_TIGR02353.1"
                     /locus_tags="AB852_RS00060"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11946..11987
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00060_0002"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="AB852_RS00060"
                     /protein_end="123"
                     /protein_start="109"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LAVLAAGAAYVPVD"
     CDS_motif       12408..12467
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00060_0003"
                     /evalue="2.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="AB852_RS00060"
                     /protein_end="283"
                     /protein_start="263"
                     /score="29.4"
                     /tool="antismash"
                     /translation="AWIIFTSGSTGTPKGVAVTH"
     CDS_motif       12600..12629
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00060_0004"
                     /evalue="5.80E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="AB852_RS00060"
                     /protein_end="337"
                     /protein_start="327"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="WRHGACLVPV"
     CDS_motif       12963..13013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00060_0005"
                     /evalue="2.00E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="AB852_RS00060"
                     /protein_end="465"
                     /protein_start="448"
                     /score="17.0"
                     /tool="antismash"
                     /translation="PMGATGQLVIGGAGLAR"
     CDS_motif       13125..13187
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00060_0006"
                     /evalue="6.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="AB852_RS00060"
                     /protein_end="523"
                     /protein_start="502"
                     /score="28.0"
                     /tool="antismash"
                     /translation="FLGRADEQIKLGGRRIELGEV"
     aSDomain        13476..13679
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AB852_RS00060_PCP.1"
                     /evalue="1.50E-17"
                     /label="AB852_RS00060_PCP.1"
                     /locus_tag="AB852_RS00060"
                     /protein_end="687"
                     /protein_start="619"
                     /score="55.5"
                     /tool="antismash"
                     /translation="EAWLAEQWSEILGVPVTGADDDFFAIGGNSLAAAQLTTRLRARHP
                     GAAVLDIYQQPVLRKLARRLEKS"
     aSDomain        13734..15791
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AB852_RS00060_TIGR02353.1"
                     /evalue="1.20E-253"
                     /label="AB852_RS00060_TIGR02353.1"
                     /locus_tag="AB852_RS00060"
                     /protein_end="1391"
                     /protein_start="705"
                     /score="835.3"
                     /tool="antismash"
                     /translation="ALQTLLLLPLFTLAGLRWTVGVLALGNVLHLFGAYPWAPTASWWL
                     VAAGAAVFFSPPGRLALAAGGARLLLRGVGPGRYPRGGAVHLRLWTAERLAELVGATAL
                     TGAWLERYARALGARIGPDVDLHSLPPVTGLLRLGRGCAVESEVDLSGHWLDGDRLHIG
                     AVRVGAGAVVGTRSLLFPGARVGKRAEVAPGSAVTGQIPTGQRWAGAPAVKLGKAKRDW
                     PGERPPRSAGWRAMYGATGLGLLALPLLAAVPALLVAAVFVAPGAGPADALRGALVAVL
                     PAALAFGFGYALLLLTAVRLLSLGLRTGTHPAHSRTGWQAWTVTQLMDLSRETLFPLYA
                     GLITPVWLRLLGMRVGRGAEVSTVLALPSLTTVGDGAFLADDTLTAPFELGGGWLRIGR
                     AEIGRRAFLGNSGMTAPGRSVPDGGLVGVLSATPKKAKKGSSYLGLPPVRLPRAAADAD
                     HSRTYEPPARLLWARGLVELCRLVPVFCSTALAVLTVLALSALARTLGPGAAALLSGAV
                     LLTAGLTAALVAVLAKWLLVGRHRTGEHPLWSGFVWRNELADTFVEVLAVPWFAGAVPG
                     TPLLTLWLRALGARIGRGVWCESHWLPETDLVTLGTGATVNRGSVLQTHLFHDRILRTD
                     TVDLREGATLGPNGIVLPGSTVGARSTLGPASLVMAGESVPAETRWLGNPI"
     gene            15893..17218
                     /locus_tag="AB852_RS00065"
                     /old_locus_tag="AB852_00065"
     CDS             15893..17218
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988033.1"
                     /locus_tag="AB852_RS00065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00065"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_073782308.1"
                     /transl_table=11
                     /translation="MNGPRPPAPDPYFPANGDARYRVHRYELSLDYRPGPNRLAGTARL
                     GAIAGRAPLTEFQLNLADFRIGRVRVEGRQPRWTHRGGKLRLWPTKPLRAGAAFTVEIH
                     WSGNPKPVSSPWGGLGWEELTDGALVASQPVGAPSWYPCNDRPADKASYQLAVTTPSAY
                     GVVAGGRLLTRTTRASTTTWLYEQAAPTSSYLVGLAIGKFQTVLLGDPGLGGVPQSAHL
                     PSHLLPEFSRDFARQPRMMELFGELFGPYPFGEYTVVVADEELDVPVEAQGMSLFGTNH
                     VDGARGSERLIAHELAHQWFGNSVGIADWRHIWLNEGLAKYAEWIWSERSGGRTADELA
                     SVAHRMLAGLPLDLRLADPGRRHMFDDRVYERGGLAVHALRHALGDDAFFRMLRGWTAQ
                     HRGGSVTTATFEAHAARYADGPLDEVFADWVHGAALPPLPVG"
     gene            complement(17310..17993)
                     /locus_tag="AB852_RS00070"
                     /old_locus_tag="AB852_00070"
     CDS             complement(17310..17993)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013672.4"
                     /locus_tag="AB852_RS00070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00070"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_079184186.1"
                     /transl_table=11
                     /translation="MRTISHPTGHRRSRTALAGVVLAGALTGSVMIAAPAAVAAPAPKV
                     VYLTFDDGPGVHTPKVLDLLKQHGAKATFYQTGANVTANPATAKRAHREGHSVQNHTWS
                     HVDLRTVSWSKFKSEVTRTDTAIRTHTGKTPTCLRPPYGAVNQTVRDRAAALRKGVRLW
                     SVDTRDWARPGRAAIESRVLNNVRNGSVVLLHDGGGDRSQTVAALPKILKTLKSKGYTF
                     GKQTC"
     gene            complement(18360..21221)
                     /locus_tag="AB852_RS00075"
                     /old_locus_tag="AB852_00075"
     CDS             complement(18360..21221)
                     /GO_function="GO:0015440 - ABC-type peptide transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979442.1"
                     /locus_tag="AB852_RS00075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00075"
                     /product="NHLP bacteriocin export ABC transporter
                     permease/ATPase subunit"
                     /protein_id="WP_073782310.1"
                     /transl_table=11
                     /translation="MTAPPVTGAGAGDAAVVLGAFGALGVRVPDAEPPDLAAAGPQTLW
                     LVEDGAVDLFAVDTAGPGHWHFLGRLGPGTLLLGPAGGPRHTLVARPLRGCALRRVGLR
                     ELPWPVGGGWPAAGTGTEYPGALEYAFALGVGRALGTLFAGPLGDGPVADGGVADGGAG
                     DAVLWPEVPPGAVAYGPDPAGGAAGELLVDAGLWRRMVEQQRRLLTALDRWIEELERGH
                     EDRAAAGVRAGEAVRAEADRTLVDALADGAAPTRERRRPRGPGGTDAAYAAVRAVGAAA
                     GIAVARPRPGTGPDERTDPVERIARDSGVRTRRVRLDGRWWRRDMGPLVGFRSAGGTPV
                     ALLWRRGGYEAVGAGPGRGVRVGARDAGEFEDRAVMLYRPLPDRPLGPLGLLRFCLRGS
                     GADLRRLALCAVVTVVLGALVPIATGHVLGVLVPAGDRAAIGRLCLAVITGGVVTAAFL
                     LTQNLTVLRLEGRIESVLQPAVWDRLLRLPTGFFTRRATGELAGAALGVGTIRRLLSGV
                     GPVLVQAGTLGAANVVLLWVYGGPLAPVALGALVVIACSFLGLGLWQLRWQRRLVTLGN
                     KLGDRAYQTLRGLPKLRVAAAEDYAYAAWAREFAHSRELQRRVGRIRNVSAVLGALYLP
                     VCTLVMFALLAGPARGSMPAGDFLTFSTALTLTLMSATQLTGALVSVAAAWPVFEEIRP
                     VLDARPEVGAGRVRPGVLAGAVEARDLSFRYTDEGPPVLDGVSFAVRPGEFVAVVGPSG
                     CGKSTLLRLLIGFDRPLSGSVLYDGQDLAALDTAAVRRQCGVVLQDAQPFTGSVLDCVR
                     GTEAFSVEEAWEAATMAGLADDIRRMPMGMHTMVAGPGTVSGGQRQRLMIARALIRRPR
                     MLFLDEATSALDNATQRVVIDSTRALNATRLVIAHRLSTVLDADRVLVMDGGRIVAEGP
                     PSVLLADTGGPLRELVREQWGDG"
     cand_cluster    19353..29568
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    19353..29568
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[24352:24568](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(24353..24568)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            complement(21223..23460)
                     /locus_tag="AB852_RS00080"
                     /old_locus_tag="AB852_00080"
     CDS             complement(21223..23460)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883900.1"
                     /locus_tag="AB852_RS00080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00080"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_079184187.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-36, bitscore:
                     122.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRHRTRSGSGEASARHRAAERAPRRRAPRAVRTPTVLQMEAVEC
                     GAACLAMVLGHFGRHVPLEELRIACGVSRDGSRASNLLKAARGHGLTAKGMQMDTAALA
                     GVAAPAVLFWEFNHYVVYDGTRRGPGRAGVYVNDPARGRRFVPMEEFDAAFTGVVLVME
                     PGPGFRRGGRRAGWAGALPARLAGTSATTTAVVLASLLLVAVGAAVPALSRTYLDLFLI
                     GGRTESLGALLTGLALAVLLTGVLTWTQQGNLLRGRLVSSTLTSARFLRHLLRLPVTFF
                     AQRGPADLVQRLQSNDAVAETLARDLSAAGVDAVVVLLYAALMWSYDPQLTLLGVAVAL
                     LNVGALRWAVAARADGTRKLRADAARLINTSYSGLQMIETMKATGGEDGWFQRWAGQHA
                     VTLEEQQRLGVPTAWLGVVAPTLATLNSALILWIGGLRAVDGLLTVGLLVAFQALVTRF
                     TAPLARLGSVAGRIQDFAADVARLRDVEGFPAEARRTGADRDAAGPRRLAGHVELKDVT
                     FGYSPLDAPLLKGFSLEVGPGRQVALVGGSGSGKSTVSRLISGLYTPWEGTVRIDGEPV
                     GELSRGTLAASVAFVDQDVFLFEGTVRDNIALWDPSVPDEAVVEALRDAELYDVVTRRP
                     GGLDARVEQDGRNFSGGQRQRLELARALVRRPSVLVMDEVTSALDSGTERLVVDNLRRR
                     GCARVVIAHRLSTVRDSDEILVLRHGEVVERGRHDALLAAGGPYAELAAER"
     gene            complement(23457..24263)
                     /locus_tag="AB852_RS00085"
                     /old_locus_tag="AB852_00085"
     CDS             complement(23457..24263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676667.1"
                     /locus_tag="AB852_RS00085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00085"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_073782314.1"
                     /transl_table=11
                     /translation="MQFRQRALAKARSPEELDLPVRLARPQGRLALAVCALVLAASGGW
                     AVTGGVPSELSAPGVLTHGHGGHVLQSPVAGQVTAVVAEEGERLAAGAPVLRVRTADGD
                     RAVRAVAAGRITSLAVSIGAVVTAGAEVALVERVGRDGEPLIALLYVPADRAAAVTVGA
                     RVEVTVESVPARRYGKLGGVVREVGRTPQSARRIGAFLGDARLGAEFTRRGLPVTVEVR
                     LDRDPATRSGYRWSAPPGPPYPPGSMTRASGAVRLPAQRPIDWLLP"
     gene            complement(24353..24568)
                     /locus_tag="AB852_RS00090"
                     /old_locus_tag="AB852_00090"
     CDS             complement(24353..24568)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="AB852_RS00090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00090"
                     /product="hypothetical protein"
                     /protein_id="WP_073782316.1"
                     /sec_met_domain="strepbact (E-value: 2.5e-29, bitscore:
                     98.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDITPQVETAEISDSDLDNVSGGLVGDVLGTVASTADSVAPVSAT
                     LGTVTGGVEDTSGLSTAPVAGLVAGL"
     misc_feature    complement(24539..24554)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            complement(24987..26840)
                     /locus_tag="AB852_RS00095"
                     /old_locus_tag="AB852_00095"
     CDS             complement(24987..26840)
                     /NRPS_PKS="Domain: AMP-binding (22-479). E-value: 5.1e-78.
                     Score: 254.4. Matches aSDomain:
                     nrpspksdomains_AB852_RS00095_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005316371.1"
                     /locus_tag="AB852_RS00095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00095"
                     /product="AMP-dependent synthetase/ligase"
                     /protein_id="WP_073782318.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-75, bitscore:
                     251.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREISVPRLVEPLAAGGLADEVFDRARREPDTVAMSLGGDRPGGV
                     WVPLTAAGFRDEVMGVAKGLLAGGIRFGDRVALMSRTRYEWTLFAFALWTVGARVVPVY
                     PTSSTDQVRWILRDTQVSAVVVEDEGHAMTVAAVCDGLPLFSRIWQLDAGCVEQLVAEG
                     AQVPDEEVHRCRAAVRPEQIAAIVHTSGTTSPQPRGCLLTHRNLAYGTDTLVGGWGEVL
                     TAEDGDRSLLTFLPMAHVCGLMIAVAAVRRGVRLAHQPDMRPGALLPSLASFRPSCVIA
                     VPHVFERIFRQARRRAELGGKAAVFDRAVSVAVRYAEAVERERHGEGTGPGAGLRMQHA
                     LYDHTVYARIRAVFGGRARCAVSGGSTLRRRLGLFFAGAGITVYDGYGLTETSGGCAAQ
                     PPGAVKFGTVGKPLPGDSLHIAADGEIWVRGDNVFLGYLNDVRASRTALRGGWFGTGDL
                     GFLDDDGYLVITGRKNDLIVTSTGRTVAPLALEERVRDDPLVSQCVVVGDDQPCLAALI
                     TLDPAAVAHWRKLTGQGGGDGEDTALRAMVQRAVVRANSGVSPAESIRAFHILPAEFTV
                     GGGLLTPSFKVRRGAVVEAFAAEIEAMYAAPRPSGGSASLV"
     aSDomain        complement(25404..26774)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AB852_RS00095_AMP-binding.1"
                     /evalue="5.10E-78"
                     /label="AB852_RS00095_AMP-binding.1"
                     /locus_tag="AB852_RS00095"
                     /protein_end="479"
                     /protein_start="22"
                     /score="254.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FDRARREPDTVAMSLGGDRPGGVWVPLTAAGFRDEVMGVAKGLLA
                     GGIRFGDRVALMSRTRYEWTLFAFALWTVGARVVPVYPTSSTDQVRWILRDTQVSAVVV
                     EDEGHAMTVAAVCDGLPLFSRIWQLDAGCVEQLVAEGAQVPDEEVHRCRAAVRPEQIAA
                     IVHTSGTTSPQPRGCLLTHRNLAYGTDTLVGGWGEVLTAEDGDRSLLTFLPMAHVCGLM
                     IAVAAVRRGVRLAHQPDMRPGALLPSLASFRPSCVIAVPHVFERIFRQARRRAELGGKA
                     AVFDRAVSVAVRYAEAVERERHGEGTGPGAGLRMQHALYDHTVYARIRAVFGGRARCAV
                     SGGSTLRRRLGLFFAGAGITVYDGYGLTETSGGCAAQPPGAVKFGTVGKPLPGDSLHIA
                     ADGEIWVRGDNVFLGYLNDVRASRTALRGGWFGTGDLGFLDDDGYLVITGRKNDLIVT"
     CDS_motif       complement(25521..25571)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AB852_RS00095_0001"
                     /evalue="9.60E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="AB852_RS00095"
                     /protein_end="440"
                     /protein_start="423"
                     /score="14.8"
                     /tool="antismash"
                     /translation="GEIWVRGDNVFLGYLND"
     misc_feature    complement(26948..26958)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(27048..28484)
                     /locus_tag="AB852_RS00100"
                     /old_locus_tag="AB852_00100"
     CDS             complement(27048..28484)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1246: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962373.1"
                     /locus_tag="AB852_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00100"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_073782320.1"
                     /transl_table=11
                     /translation="MSPSDRSAGAARDTPHRHAVVIGAGVAGLAAAAALRGHARVTLVE
                     RDTLPEGPESRKGLPQARHAHLLWSGGARALEELLPGVTARWLAAGARRIALPTGLVSM
                     QPSGWIRRFPELQFMIAASRDLLDWGIRQSVAEDPAVTVLEHSELLALEGDARRVTGVR
                     LRVGPGQGAEERFLAADLVVDASGRGSRAVAQLAALGVPRAAEEEVDSGLVYASRIFRA
                     PPGTEDFPVVNVQADAREARPGRTTTIVPIEGERWLVTLSGTRGGEPGPSPEGFEPFAR
                     TVRHPVVGELIARAEPLTGVRVTRSTVNRRRFFERVAPWPDGFLVLGDAVATYNPVYGH
                     GMSVAAEGALALRQLVDAEGLGTPGQARRAQRAVARPVSVAWDLATAQDILYPGSIGRR
                     PGPSAKAARRYVDRLMRTASARPLVAKALLDVMTLSAPMTALVRPEVVFAVLRGPRLPP
                     LAGPPLTDRELATALGSGHH"
     gene            complement(28468..29673)
                     /locus_tag="AB852_RS00105"
                     /old_locus_tag="AB852_00105"
     CDS             complement(28468..29673)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999409.1"
                     /locus_tag="AB852_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00105"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_073782323.1"
                     /transl_table=11
                     /translation="MNGPDYYLPAAATGIALAFKFPSLLREWRDPLLRSVCALLALGTS
                     VFFFSAPPTIAQVNRITGVPNISGPLVYALLSAFSASCLVLMVNWRGGPPEVTRRVSRR
                     WIAGYTAVSVALVVLFALGDAPVERLRDLDTYYANTPYIREMIVLYLTGLTVAGVAMAY
                     LCLRWSLQVRGLLRAGLSAIAVGYLFNLSYAATKFTAVFARWAGHDLDWLSSETAPLLA
                     SAAALFSAIGFCLPLAFQRLGEQVTVWSTYRRLGPLWRELRGLGPHGVAPSRISWWPSA
                     DLLVTQRESDIHDGMLSLYPYFDSRVHARAHAAAVASGNGPAQARAVADAAMVTAAVRA
                     RAADPEGTALARPDGPPDTAVSGEGPRDLVRMSLALRHSPVVAAARTAVARSESGTHEP
                     IR"
     gene            complement(29677..30213)
                     /locus_tag="AB852_RS00110"
                     /old_locus_tag="AB852_00110"
     CDS             complement(29677..30213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983182.1"
                     /locus_tag="AB852_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AB852_00110"
                     /product="toxin-antitoxin system, toxin component"
                     /protein_id="WP_073785136.1"
                     /transl_table=11
                     /translation="MRKLCGELIAGLPPEIPDTPGALIGALCATMSRRRGRPVNHRMAA
                     FPPGTASGLWLDMADQDLIVIEERTAPDHQLVILGHELWHMTAGHSTRHVDAAGTGVAA
                     RLLAGGVDLQDTVRRVAARSRSHAVEEEEAESFGLLLASKCRSRTAGPAGRGQAPRDEL
                     TARIEASLGYRRPQG"
     misc_feature    30298..30310
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     misc_feature    complement(30370..30384)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.0"
                     /tool="antismash"
ORIGIN
        1 ctggcacaac cacaaaaccc gccagccggt cacacgatca ctgatcgcct acgaccactg
       61 atcgttcgga atgactcgtc tagcacttgt cgccagagtc cgaccatggt gtgcgcccct
      121 cgtgcccgga ccaggcgccg cgaactctga ctgtcagggg cgacggttag cgtgcggcca
      181 tgagtgaaat ccagcagaac ccgatgacgg ctcagtcttc ccggtccgag gccacgcaga
      241 acgcagcccg tcctgtgcgg ccggaagtcg atgcgaagcc gaagggcatc gcgctgtacc
      301 acgacatgcg agtcgaagag gacttcgcca agtgtgccac ccgcctcttc tcgatcctca
      361 agaaggccgc agcgacaagc cctggcgctc cacgttacgt ttacctcgac atccaggggc
      421 accgcaacgc cgccggcggc tatgacgccg atgccttgga gatcatccgc gagttcttgc
      481 tggggttcct ctgtccgtat ctcacagaga tcagcacacc gctctatcat gtgaggaacc
      541 ctgagtcgca acgcgaagac atccctgatg tcctcaacgt acgagacccc tacggtgaac
      601 actcttacga ccaccgtgag ttgcgtgtac gtaaccggga cagcagtcct gaccagcggc
      661 ggtccagacc gccggtccgt gctatcgccg actatcttgg cctcgatgag ccgatctgcc
      721 tgatctgctg gcaggcgccg gtggagaggg cccacgtagt ccccgagtcg ctcggcggct
      781 ccaacgatgt gcggaacttt gccctcctct gcccgcgcca tcaccgtgag gctcccgatg
      841 tcgcggacgc cgaggcgttc tggtcctggg tcgactacgc ctgtgaacgc gacggccata
      901 tgaagtggga aggcgtggac ccggagatac tggcgaaggc ggaacgcgtt ggccttcaga
      961 ttgaaacacg cggatcggta cggaagagcc tgcgtcattt cgaccgggtc cgtgacgaac
     1021 tcatgcgtca ctacggctgg tgcccggagg acttcgccgg cggctaccac tggggagcgc
     1081 tgatggaaga gttccacacg gtgatggact cggcaaccag cactcacttc aacgttccta
     1141 agaaggcatc caccgaagcg tgggccttcg aagtggcccg cagacgcctg agagacggag
     1201 tagcggagcg cgaggctgac aatcacgagt cggcggcgtc aggccgtctg tcgattgagt
     1261 tggcggagtg gacgatgcgc aagtcgcccg agagccacgg tgcacagaac ctggtcgatg
     1321 ccgcccggcg ggccgacatc gcgatcgagg cggcggcact cgtgcgcgac atcatctctt
     1381 cagcgggggt ttccagcgcc gaggaggtgc tgcggggcat catggaggag gtgaccgacc
     1441 gcaccgcaca atttgatcgg ctgaatgatg agttgatggg acaagcgtcc tgccgatact
     1501 gcggtcacgc tatcgcccgg attggggaca ctccctggcg ccacagcgct gcggcaccca
     1561 tgtctcgtgg ctgccgggcc gcgagttttg atcgggacgg caattgggat gattctctcg
     1621 atcgagcgtg ggtggcaagt ccgccgaaga gctatcggtg agctgttcac agttgccggc
     1681 cgagtcacgg tgcggtgcgt catcggaatc gctgggagtt gccgccacta gatgagcgtt
     1741 cccccggtca gagcgacttg gagctggtgc gcgggcgaag agatccagcc ccctcgggca
     1801 taaggtgaaa ccccaggtca cctggggttc ttttgctgtg tccggcggcc tcggacccgg
     1861 accgcgccgc tgggcgcgga tcgctccctg gcctgactcg ggtccgctac cccgggtagc
     1921 gctggacgat gcggccccac cgtacgcacg ccaccgtcgg caggcacgtc gccaggatca
     1981 gccaccggtg cggcagggcc cggtggcgca aggcggcgta gttgagcgac tcggtgagtg
     2041 cggcggtcag gagcagtagg gaacaggccg tctcgatgcc cgtcagggtg ttctcgtccc
     2101 aggctccgcc gggcgtggtg gtgaccacgg cgtaggcgag gtagaggttc acggctttgg
     2161 ccgggacgag cagggccggc catggcgtgg cggagggacg gcggggcatg ggaggcaggt
     2221 ctcgggaggt ccggatcgcc agccgtggcc ggatcgcggg tcgggtgccc gaatccgttt
     2281 ccggcccggt gccgcgcagc caaccgtacc tggactcggg ggagttcacg gcacgatgac
     2341 ctcagcccac cgtcgccgac tcccggggtg tggggtcccg gagggggcgg gttcggtgca
     2401 aggtgtggat gtcgcggccg aaggaccagg tcagggtggt cagggcgagg aggatcacgg
     2461 gcagggtcag cggccggggg aggtaggtgg cggccgcgag gagggccacg ccctggagcg
     2521 cggcgaccga cttgcgggcc gtgctcggcg tcaacggggc gttcagccag ggcagtaccc
     2581 gcgcggcggc cacgaacccg taccgcatca gtccgatcag caggacccac acccccagcc
     2641 gggcggagac gtacacactg agcaccagga tcaggaacgc gtccacctcc atgtcgaacc
     2701 gggcgcccaa ctccgacacc gtccccgtgc gacgggccac caggccgtcc acggcgtcca
     2761 ggatcagggc cacccccgcc agcgccgcca gcgccgccac ccggggcggg ccgtcgagcg
     2821 agtccgccac cagggccgtc accccgccga ccagggtcgc ccgcgccagc gtcacccggt
     2881 tcgccggacc gaacgggccg ggccgcgccc ggcgcagggc gcggatcagg agcacccagg
     2941 tccccaccgc gaagacgagc cccgtcagcc gtcccgccgg gcccagcccg acggtcccgg
     3001 ccagcagcgc gagcagtagc acctgcgcca ccgcgcccgc cgcgatgtca tgccgcgcca
     3061 gccgcgttcc gtcctcgcca gatgcctggt tcagggccat cgcgcacctt ccgccctggt
     3121 gacagggctg attcccgccg cgtaccgtac tcgcggtctc tgctctcagt acgtggggcc
     3181 gaccgggacc gttcaccacc agtgctgtcc cggcccgccc gccccatccg cgccacgccc
     3241 gcgacaggag ctgttccttg gtcctcagcg cacctcaccc cgcaggtacc ggacagggtt
     3301 ccggtaccgg tccggcgggc gctcgtaccg cccgtgccta ctggctgcgc gcacccgggc
     3361 agggggagat ccgcgaagtg cccctgcccg aaccggggga cggtgatgtc gtcgtgcgga
     3421 gcctgtactc cggggtcagc cggggcaccg agaccctggt gctgcgcgga ggggtacccc
     3481 gcagccagca cactgccatg cgcgcgccct tccaggaggg agacttcccg gcgcccgtga
     3541 agtacggata tctcaacgtc ggtgtggtgg agggcggctg cgccgcgctc ctcggccgga
     3601 ccgtgttctg tctgtacccc caccagaccc gctacgtcgt ccccgccacc gccgtcaccc
     3661 cggtccccgg caccgttccc gccgcccgcg cgatcctcgc cgggacgatg gagaccgccg
     3721 tcaacgccct ctgggacgcg gcgcccctgg tcggtgaccg gatcgcggtc gtcggggccg
     3781 gaatggtcgg cgcctgtgtg gcggccctcc tcgtccgctt ccccggcgta cgggtgcaac
     3841 tcgtggacgc cgaccccgcc aaggccgccg tcgccgacgc gctcggggtg cggttcgcgg
     3901 cgcccgacga cgcgctcggc ggctgcgacc tcgtcgtcca cgccagcgcc accgaggccg
     3961 ggctggcgcg gtccctggaa ctgctcgcgc cggagggcac cgtgctggaa ctgagctggt
     4021 acggcgaccg caaggtgtcg ctgccgctgg gggaggcgtt ccactcgggg cggctggtgg
     4081 tgcgcgccag tcaggtcggg gcagtgtcac cggcccgccg ttcccggcgg gacttccgcg
     4141 accggctcgc cctcgcgctc gacctgctcg ccgaccccgc cctcgacgcg ctgatcaccg
     4201 gcgagtccgc cttcgacgac ctgcctcgcg acatggcgcg tatcgcggcg ggggaactgc
     4261 ccggactctg ccaccgtgtc gtctacggga gcgaggggcg gtgggccccg tgaccggagc
     4321 ggcgcccgga gaggctgtcc gggccgcgat cctggccgtg cccctggctg tgaccgcgcc
     4381 ggggccaggt cggtgacccg ggcccactcc ggccgccgcg gccgggccgt gacccgggcc
     4441 gtgaccccca gccctgctga ccggcgcacc cgcgtagccc acccgtacga catccgtacg
     4501 acatccgtac gacatccgta cgacatccgt acgacatccg tggttccggg aggtgacttc
     4561 gctgaacgag acaccggcgg cagccgtata ggacaggagc cccggcagcg caccgacatg
     4621 ccgtactgga gggtcaaccg ttgttcagca tcaccgtccg tgaccatctg atggtcgccc
     4681 acagcttccg cggcgaggtc ttcgggcccg cgcaacgtct gcacggggcc acgttcctcg
     4741 tggacgccac cttccgtcgc gccgaactcg acgcggacaa catcgtggtg gacatcgggc
     4801 tggccacccg cgaactcggt acggtcgtcg ccgcgctgac gtaccgcaac ctggacgacg
     4861 agcccgactt caccggcgtc aacacctcca ccgagttcct cgccaaggtg atcgccgacc
     4921 ggctcgcgga ccgggccgcc tccggcgcgc tcggggaggg cgctcgcgga ctcgccggga
     4981 tcaccgtcac cctccacgag tcgcacatcg cctgggcgag ttacgagcgt gccctgtgac
     5041 ccgcacggac acacccgccg ccgtcacatc ccaggcagcc acgtcccagg ccgtcccgcc
     5101 cgtgggtccc gcccgccccg gcgccggtgc gactgccggt acctcggccg gtacgcccgc
     5161 gcacacgggt acgggtacgg gtaggtccgc cagtgcgtcc gccggtacgg gtaccagtac
     5221 ggccgccggt acctccgtct cctcgtcctc ccgcatcgtc ccgaccgacg cccggccgat
     5281 gcacttcgtg atgcccggcg gtgtcgacga cccggccgcg cccagtggcg gcaacaccta
     5341 tgaccggcgg gtgagtctgg acctgtccgg cttcggctgg gacgtccggg cgcacaccgt
     5401 ggacggcgac tggccccgcc ccgacgccgt cgccacggcc cgcctcgccc acaccctcgc
     5461 cgcactgccg gacggcgcgg tcgtgctcct cgacggcatc gtggcctgtc cggcgcccga
     5521 gaccgtcgtc gccgaggccg aacgcctgcg actggcggtc ctggtgcacc tcccgctcgc
     5581 cgacgagagc gggctcgacg aggcgaccgc cgcggagctc gacgccctgg aacgcaccac
     5641 gctgcgcgcc gcggccgcgg tcgtcgcgac cagcgactgg gccgctcaac ggctcgtcag
     5701 ccaccacggg ctggccagcc gccgggtcca tgtcgccgcc cccggcaccg acatcgcgcc
     5761 cctggcgacc ggcaccgacg ggatctcccg gctgctgtgc gtgggctcgc tcaccccgcg
     5821 caagggacag caccggctgg tccgcgcgct ggccacggtc gcggacctgc cctggagctg
     5881 cgtcctggtc ggcggtctcg accaggaccc cggctatgtg tcccggctgc gcgccctcgt
     5941 cgacgaactg gggctcaccg gccgggtacg gatcgccggg ccccaggtgg gcgccgagct
     6001 gaacgccagc tatgcccgcg ccgatctgat ggtcctggcc tccgacagcg agacctacgg
     6061 catggccgtg acggaggccc tcgcccgggg catccccgtc ctggtcaccg agatcggcgg
     6121 gctgcccgaa gcggtggggc gcgcacccga cggcagcgtt cccggcgtcc tgctgccgga
     6181 caccgacccg gccgccctcg gcacggccgt ccgccgctgg ttcgacgagc acgacgaacg
     6241 ccagcggctc aaggcggccg cccggtcacg ccgcacctcc ctcgacggct gggccaccac
     6301 cgcccgcagt ctgtccgggg tcctcgaaca gctccgccgc gacacctgga gcgcggtgtg
     6361 acggcgaccg ccgaccccac gaggttcacc cccgactggc tggccctgcg cgaacccgcc
     6421 gacgcggcgg cccgctccgc cgcgctcctc ggaccgctgc ggcccggact ggtcgcccac
     6481 gcgcggtccg gaactccatt ggtcgtccac gacctggggt gcggcgccgg gtccatggcc
     6541 cgctggctgg tgccccggct ccccatggca cagcactggg tgctgcacga ccacgacccg
     6601 gacctggccc ggcttgccgc cgagcggaca ccccgctccg ccgccgacgg ttcaccggtg
     6661 accgtggcca cccgcggcgg ggacgtgtcc cggctgacgg cgtccgccct cgccggtgcc
     6721 tcactgatga cgatgtctgc ttttcttgac atcgtcactt cggacaccgt cgacaggctg
     6781 gcggcggcct gcgcgggtgc cggctgcccg gcgctgctca ccctctccgt cgtcggccgg
     6841 gtggaactca cccccgcgga cccgttcgac gcggatgtcg cccgtgcctt caacgcccac
     6901 cagcgccgct ccgggctgct cggacccggc gccgtcgagg cggcgaccac cgccttcacc
     6961 cggcacggga tgacggtccg ggtgcacgag agcccctggc gcctggggcc cgcccatgcg
     7021 gccctcaccg ccgaatggct gcgcggctgg accggcgccg cccgggatca acgccccgac
     7081 ctcgccgccc ggctggacgc ctaccgcgcc cgccggctgg ccgcctgcgc gacgggcgac
     7141 ctgcgggtga ccgtccacca cgccgacgtc ctcgccctcc cccgaggaag ccgcaccccc
     7201 catgccccca ccccctgacc cccgcaccac cccggcatca cccccacccg cacccgcact
     7261 ttccgcccgt ccggcgagca cctgtacggg tacggacacg ggtacgggta cgggtacgga
     7321 cgacgccggt acggatacgg cacggtcccc gcacggcggc agcaccccgc ccgtggacac
     7381 cccgcccggt catggctccg acggcgacgc caagtccgga caaggctccg acggcaacgc
     7441 cccacccggt cacgccccgc ccaaccccgc cctgcacggc cacaccccga aacgcgatcc
     7501 gccgggcagg ctccggacct ggctgccgcc gctcgccggg gcggcgatcc tggccctgct
     7561 gctgtcccgg ctcggcacct ccgccgtcac cgaagggctg acccgcgtca ccccggacgc
     7621 ggtgttcgcc gccctggctc tcggcgcctt caccacggtg ctcagcgcct ggcgctggca
     7681 cctggtggcc cgcgcgctgg gcctcggcct cccgctgggc agggccgtcg ccgactacta
     7741 cggggccctc ttcctgaact cggtcctccc cggcgggatc gtcggggacg tggaccgcgc
     7801 ggtacggcac ggccggggca gcggggaact ggggcggggc gtgcgggccg tggtcctgga
     7861 acgcacggcc ggacagctcg tcctcctggc ggtggccgcc gtggtcctga ccacgttccc
     7921 gtccccggcc gccgaccacg cccggcgggc gctcaccggc ccgtggaccg cggccgtcct
     7981 ggcggtcggc tgcggggcga cggcactcgt cgtcgcgcta cgcgcccgtg ccgccgcagg
     8041 ggccgatgcc cgccccgccg ctcccgccgc tcccgccgct cccgccggta cccacggtgc
     8101 cgtccgagcc acctcggccg cccccgctac ccccgccacc cgcgcccggg cggaccgccg
     8161 tgccctgtac ggacgccgta ccgcccccgc cgtcctcggc gtctccgccg ccgtgctcgc
     8221 cgggcacctc gtcctgttct ggctcgccgc ccgggtctcc ggggtcaccg ccccgttcgc
     8281 cgtgctgctg ccgctgatgg tcctcgcgct gctcgcgatg tccgtgccgc tgaacatcgg
     8341 cggctggggt ccccgggagg gcgtcaccgc ctgggcgttc ggcgccgccg ggctcggcgc
     8401 cgcccagggc ctcacggtct cggtgctgta cggggtgctc gccgtcgtcg cggccctgcc
     8461 cggtgccctg gtcctaccgg cacgctggtg cgcacggccg ggccgctccc cgcgccgccc
     8521 gctacgcgtc cgtgaggtcc agctcgaaga gggtgtcctc cccgaggcgg gcgcgccgca
     8581 gcgggggacg ccgtgcctcg cgcatcacgt ccggcccgtc gaaccgcagc ccgggcaccc
     8641 cgtccccgag cagcaccggc gcgaccgtga cgtacagccg ccgcagggcg ccgccgtgca
     8701 ggaagcggga gacggtgacc ccgcctccct cgacgagaac ccggccgagc ccccggtgcg
     8761 ccagcgtggc gaccagccgg cggggcgtga acgcgtcgtc gtccggcagc cgcagcacgg
     8821 tcaccccgtc ggcgacgggc cgcccggggc cgctgccggg gcccaccagc cacagggtgg
     8881 gcgctgatcc gtcggtgaac acccggcggt ctgccgggac gcgcccccgg gggtccagga
     8941 ccacccggac gggatgggcg cccgcgcagg cccggacggt gagctgcgga tcgtccgcga
     9001 cggccgtacc cgcgccgacc aggaccgcgt cggcgagcgc ccgcagccgg tgcagatgac
     9061 ggcggtcctc ctcaccggtg acgtagtcgg cgtccccggt gcgggtcgcg atgaatccgt
     9121 cgaggctctg ccccagctgg gcgaacgtga cacggggccc cgcgaggcac agcgggaggt
     9181 agcggtcggc gaggtcggcc gcctcggtgc tcgcgggccc ggcccagcgc cagccgccgt
     9241 ccggtccggc gacgagcccg gcggcacggg cgtccgccgg ggcgcgcacg tcgagcagcc
     9301 gccgccatgc ctcgtccccg gacaactccg ctgcgggtgg aagggattcc ggggtatgtg
     9361 accgtgtgtc gggtgcctcg gcggaggggg aatgcgcacg gccgtcggcg aggggccctg
     9421 cgtcgtttcc gggagtgtcc gcggggtcgt tccccggggt gggggagaga gggtggttca
     9481 tgagtcgtcc ccgtcctggg cgccgggtcc gcggagcagt gcgtggtacg cgccgaagga
     9541 ttccgtgagt gagtccagca gggccgcgcc cttctccgcg gttgcccggg agggtctgcc
     9601 cagcacaccg gtcgtggtgt attcccgcat tccgagggtc agcagatgtc tgcggtcccc
     9661 ggcggaccgg tcggtggatt catggccggg gcgcaggagt tcggggtggg tgtgcagcag
     9721 gatcgaggtc tcgatctccc cggcgtgcat gtcgtcgtgc gcggaggtcg atatcccggc
     9781 ggtctcccgc gccgccttcc agtcggcgga ttccgggaaa agcgccatgc ggattcccca
     9841 tccggcggat tcctggacga cattgcgcag gacgtagttc ccgccgtgtc cgttgaccag
     9901 taccagggaa cgtattccgg acctccgcag ggaatccgcg atgtcccgga ccatgtggta
     9961 cagggtagcg gcggaaatgc tcaccgtacc ggcccagtcg gcgtgttcat gggaacacga
    10021 gacggtgatc gggggaagtg acagcacacg atgcgccgcc gctatccggc gggacagcgc
    10081 acaggcgacg acggtgtccg tcaccagggg aagacagggt ccgtgctgct cgaaactgcc
    10141 gatggggaga acggcgacat ccgcgtcccg tgcggacacc tcggtggtcg tctccgtcgg
    10201 caggagcagg gcggcggtgc ggtcgggcgc cggttctttc atctctctcc tgtccctcgg
    10261 gtcccgtccg tcgcacagca cggccgtgtg gcggacggac ggtcgcggtg cgcggtgaca
    10321 tggcgtacgg cgtttgccgg cgactcggcg ggcgccacgg caggggcagc gtacgcgccg
    10381 cgcccaactc ccggggcagg agccggaaat gggtggttga tgatgttttt tacgacgttt
    10441 tccgccccca ggaggggggt gctgacggct atggtctgcc catgacagca gccatcacgg
    10501 aaaacggcgg cgtcggcggt gccgtcgccg gagaactcac gggggacgtg gcggacgcgg
    10561 ggagcggccg gtccgtcgtg ccggtcaacg gtgtcgagcg tgtcgtgcgg gtccgtctgt
    10621 ccaccggtca cggcgagttc ctggccgtcg gctaccggga ccacgccctc ggccaggaac
    10681 agatgctcct cgtccacggg gacatcgaag gggaacgtgt cctcacccgg ctgcattcgg
    10741 aatgcctgac cggtgacgcc ttcggctccc ggcactgcga atgcggcgga caactcgacg
    10801 cggctctctg cgcgatcacc tccgagggct ccggtgtcct cgtctatctc cgtggccatg
    10861 aggggcgcgg gatcggtctg ctcgccaaac tccaggcgat gcggctccag gccgacggaa
    10921 tggacaccgt cgaggcgaac atcgccctcg gacttcccgt cgacgcccgt gactacaccg
    10981 tcgcggcgga catgctgcac gatctcggag tgcgctccgt gcgtctgctg tccaacaatc
    11041 cccgcaaggg cgaagccctg ctgcggcacg gcatcaaggt cgccgaacgt gttccgctgc
    11101 tgatcccgcc gagcgaggag aacctggcct atcaacgcgc caagcgtgaa cgcctcgacc
    11161 acgatctgcc gcatctggat gcgatcaccg aacatctctg acggatcacc cgcgcaccgt
    11221 ccgggacacc ccgttcctgg ccccgacgcg tcgtccggcc accgcgtccg cgctcgcgtt
    11281 ccgtgttcac ccttatgccc cgcgtgtgtt cccgtgccgt ccgacgcgcg cccgcgagga
    11341 aatccgggcg aattcccggt gcactccgca cgacttcccg gcagacgatt cctcacccgc
    11401 tttccgtatt cccccccgcc gcgccccgcg ccgccttccg gaacacggaa atcacgcgtg
    11461 gtgaacgaca cccctgtacg gacgccttgc acagagaggg atcattcgcc ccggactagt
    11521 atgggcctgg ttgtttggtg ctggaccgga acaaccccag gcagagctga gggcccgcca
    11581 gcgcccggga catcccggga acgagacgcg aggacccgat ggccacgacg acacccgcca
    11641 ccgcaccgga gggcgacgat ctcgccccgc ccccgcccgg caccgccccc ggtccccccg
    11701 cccccgcggt cctcaccgcg ggtcccgccg ccccgccccg caccctggtc gacatcctcg
    11761 acgcctccgt acgccgctac cccggcgagc ccgccctcga cgacggcacc acccggctga
    11821 cctaccgggc gctcgccacc gaggtcgaca cgctccggcg ccgcctcgcg cactccggcg
    11881 tacgccccgg cgcccgggtc ggggtccgcg tcccctccgg caccaacgac ctgtacgtcg
    11941 cgatcctcgc ggtcctcgcc gccggagccg cctacgtccc cgtggacgcg gaggaccccg
    12001 acgagcgggc cgagctggtc ttcggggagg cgggcgtcca cgcggtgatc ggcgccggac
    12061 accggatcga ccccccgccc gccgcgcgca cggccaagtc ctccaagccc tccccgacgc
    12121 gcacggccac cgctccggcc gccacggctg tcacgtccac tgccaccacc accgtcacca
    12181 ccgccgcccg gaccggctcg gccgcgcgaa cccccaccgc cgcctccgcc acggccaccg
    12241 gccccggcag cccggtcggc acctccggtg accgggccgc cacccctcgc ggcccgtccg
    12301 tcacccacgg caaccccgcc acctccgagg gtcacgccga cgcgcccacc cccggcaccc
    12361 gtcccgtacc caaccccggc ggcacccgcc ccacccccgc cgacgacgcc tggatcatct
    12421 tcacctccgg ctccaccggc acccccaagg gcgtcgccgt cacccaccgt ggtgccgccg
    12481 ccttcgtgga cgccgaggcc acgctgttcc tcaccgacga ccccatcggc cccggcgacc
    12541 gcgtcatggc cgggctctcc gtcgcgttcg acgcctcctg cgaggagatg tggctcgcct
    12601 ggcggcacgg cgcctgtctg gtgcccgtgc cgcgcgccca ggtccgcagc ggcgccgacc
    12661 tcgggccctg gctcgtcgag caggagatca gcgtcgtgtc gaccgtgccg acgctcgccg
    12721 cgctctggga gcccgacgcc ctcgccgacg tccggctgct gatcttcggc ggtgaggcgt
    12781 gcccgcccga gctggcccag cggctggtca ccgagggacg cgaggtctgg aacacctacg
    12841 gccccaccga ggccaccgtc gtcgcctgcg cgtccctgct caccggcgcc gaacccatca
    12901 ggatcggcct gccgctgaac ggctgggacc tcgccgtcgt cgacgacgcc ggactccccg
    12961 tcccgatggg cgccaccggg cagctcgtca tcggcggcgc cggactcgcc cgctacctcg
    13021 accccgtcaa ggacgccgag aagtacgcgc cgctcgacgc cctcggctgg ccgcgcgcct
    13081 accgcagcgg cgacctcgtc cgggccgaac ccgaagggct ggtcttcctc ggccgcgccg
    13141 acgaacagat caagctcggc ggacgccgga tcgaactcgg cgaggtcgac gccgccctcc
    13201 aggcgctgcc cggggtcgcc ggggccgccg ccgcggtccg caccgcacgc ggcggcaacc
    13261 agctcctcgt cggctacctc gtcacccagg acggctggga ccacccggcg gccgtcgccc
    13321 ggctgcgcgc cgagctgccc gccgccctgg tgccgctgct cgcccccgtc gccgaactgc
    13381 ccacccgcac ctccggcaag gtcgaccgcg acgccctgcc ctggccgctg cccggactca
    13441 ccaccggcgg ccccgccgaa cagctctacg gcaccgaggc atggctcgcc gaacaatgga
    13501 gcgagatcct cggcgtgccc gtcaccggcg ccgacgacga cttcttcgcc atcggcggca
    13561 acagcctcgc cgcagcccag ctcaccaccc ggctgcgcgc ccgccacccc ggcgccgccg
    13621 tcctcgacat ctaccagcag cccgtgctgc gcaagctcgc ccgacggctg gagaagtcca
    13681 cccaggacga caccaccacc cggaccgtca cccccgtccc ccggcgcgcc caggccctcc
    13741 agaccctgct gctgctcccg ctgttcaccc tggccggact gcgctggacc gtcggggtgc
    13801 tcgccctcgg caacgtcctg cacctcttcg gcgcctaccc gtgggcgccc accgcgtcct
    13861 ggtggctggt cgccgccggg gccgccgtgt tcttcagccc gcccggccgg ctcgccctcg
    13921 ccgcgggcgg cgcccggctg ctgctgcgcg gcgtcggccc cggccgctac ccgcgcggcg
    13981 gagccgtcca tctgcggctg tggaccgccg aacggctcgc cgagctcgtc ggcgcgaccg
    14041 ccctcaccgg cgcctggctg gaacgttacg cccgggcgct gggcgcccgg atcggccccg
    14101 acgtcgacct ccactcgctg ccgcccgtca ccggactgct cagactcggc cggggctgcg
    14161 ccgtcgagtc cgaggtcgat ctgtccggcc actggctcga cggcgaccgg ctgcacatcg
    14221 gcgccgtcag ggtcggcgcc ggagccgtcg tcggcacccg cagcctcctg ttccccggtg
    14281 cccgcgtcgg caagcgcgcc gaggtcgccc ccggctccgc cgtcaccgga cagatcccca
    14341 ccggacagcg ctgggcgggc gcccccgccg tcaaactcgg caaggccaaa cgcgactggc
    14401 ccggcgaacg cccgccccgc tccgccggct ggcgcgccat gtacggggcc accggcctcg
    14461 gcctgctcgc cctcccgctg ctcgccgccg tccccgcgct cctcgtcgcc gccgtgttcg
    14521 tcgcccccgg cgccggaccg gccgacgcgc tgcgcggcgc cctcgtcgcc gtcctcccgg
    14581 cggccctcgc cttcgggttc ggctacgcgc tgctgctgct gaccgccgta cgcctgctca
    14641 gcctcggact gcgcaccggc acccaccccg cccacagccg caccggctgg caggcctgga
    14701 ccgtcaccca gctgatggac ctgtcccggg aaaccctctt cccgctgtac gccggactca
    14761 tcacccccgt ctggctgcgg ctgctcggga tgcgcgtcgg ccgcggcgcc gaggtgtcga
    14821 ccgtcctcgc gctgcccagc ctcaccaccg tcggcgacgg cgcgttcctc gccgacgaca
    14881 ccctcaccgc gccgttcgag ctcggcggcg gctggctgcg gatcggccgc gccgagatcg
    14941 gccgccgcgc cttcctcggc aactccggga tgaccgcgcc cggccgcagc gtccccgacg
    15001 gcggtctcgt cggagtgctg tccgccaccc cgaagaaggc caagaagggc agctcctacc
    15061 tcggactgcc ccccgtacgg ctgccgcgcg ccgccgccga cgcggaccac agccgcacct
    15121 acgaaccgcc cgcccggctg ctgtgggcgc gcggtctggt ggaactgtgc cgtctggtgc
    15181 ccgtcttctg ctccaccgcc ctcgccgtgc tcaccgtcct cgccctcagc gccctggccc
    15241 gcaccctcgg acccggggcc gccgccctgc tctccggcgc ggtgctgctg accgccggac
    15301 tcaccgccgc gctcgtcgcc gtcctcgcca aatggctgct ggtgggccgc caccgcaccg
    15361 gcgagcaccc gctgtggagc ggcttcgtct ggcgcaacga actcgccgac accttcgtcg
    15421 aggtcctggc cgtaccgtgg ttcgccgggg ccgtgcccgg caccccgctc ctcacgctct
    15481 ggctgcgcgc cctcggcgcc cggatcggcc gcggcgtgtg gtgcgagagc cactggctgc
    15541 ccgagaccga cctggtgacc ctgggcaccg gcgccaccgt caaccgcggc tccgtcctcc
    15601 agacccacct cttccacgac aggatcttgc ggacggatac tgtggacctc cgcgaaggcg
    15661 ccaccctggg cccgaacggg atcgtgctgc ccggcagcac ggtcggggcc cgctccacac
    15721 tgggccccgc gtccctggtc atggccgggg aatcggtgcc cgccgagacc cgctggctgg
    15781 gcaacccgat cgaggcgtgg cggtcctgac cggcggcccg ccaccagcac accgggcgcc
    15841 gtgcgagcca gcggcacacc gcccgagcac agcgcaggga gcggacacac gagtgaacgg
    15901 cccaaggccc ccggcccccg acccgtactt cccggcgaac ggcgacgccc gctaccgggt
    15961 ccaccgctac gagctctcgc tcgactaccg cccggggccc aaccgcctcg cgggcaccgc
    16021 ccggctcggc gccatagcgg gccgcgcccc gctcaccgag ttccagctca acctggccga
    16081 cttccggatc ggccgggtcc gggtcgaggg ccgccagccg cgctggaccc accggggcgg
    16141 caaactgcgg ctgtggccca cgaaacccct gcgggccggg gcggcgttca ccgtggagat
    16201 ccactggtcc ggcaacccca agccggtgag cagcccctgg ggcggtctcg gctgggagga
    16261 actcaccgac ggcgccctcg tcgcgagcca gcccgtcggc gcgccctcct ggtacccctg
    16321 caacgaccgg cccgccgaca aggcctcgta ccagctcgcc gtcaccaccc cgtccgcgta
    16381 cggcgtggtg gccggcggac ggctgctgac ccgcaccacc cgggccagca ccaccacctg
    16441 gctgtacgag caggccgcgc ccacctccag ctatctcgtc ggcctcgcca tcggcaaatt
    16501 ccagacggtg ctgctcggtg acccggggct cggcggggtg ccgcagtccg cccatctgcc
    16561 gtcgcatctg ctgccggagt tctcccggga cttcgcgcgc cagccccgca tgatggagct
    16621 gttcggggag ctgttcggcc cgtacccgtt cggtgagtac accgtggtcg tcgccgacga
    16681 ggaactcgac gtccccgtcg aggcccaggg gatgtccctg ttcggcacca accatgtgga
    16741 cggcgcccgg ggttcggaac ggctcatcgc ccatgagctg gcccaccagt ggttcggcaa
    16801 cagcgtcggc atcgcggact ggcgccacat ctggctcaac gaagggctcg ccaagtacgc
    16861 cgagtggatc tggtcggaac gctccggcgg gcgcaccgcg gacgaactgg cctccgtcgc
    16921 gcaccggatg ctcgccggac tgccgctgga cctgcggctc gcggacccgg gccgccgcca
    16981 tatgttcgac gaccgggtct acgaacgcgg cggcctcgcc gtgcacgccc tgcgccacgc
    17041 cctcggtgac gacgcgttct tccggatgct gcgcggctgg accgcccagc accggggcgg
    17101 ctcggtcacc accgccacgt tcgaggcgca cgccgcgcgg tacgcggacg ggccgctgga
    17161 cgaggtcttc gcggactggg tgcacggagc cgccctgccc ccgctgcccg tcggctgatc
    17221 cggcaccgtg cagcggcggc agacgggcgg acgggcgggc ggacaggtgg gtgggcggcg
    17281 ccgggggcgc cgcccgggtg gccgttccgt cagcaggtct gcttgccgaa ggtgtagccc
    17341 ttggacttga gcgtcttgag gatcttcggc agggccgcca ccgtctggct gcggtcaccg
    17401 ccgccgtcgt ggagcaggac caccgagccg ttgcggacgt tgttcagcac ccgggactcg
    17461 atggccgccc ggccgggccg cgcccagtca cgggtgtcca ccgaccacag ccgcaccccc
    17521 ttgcgcagtg ccgcggcccg gtcccggacc gtctggttca ccgcgccgta cggcggccgg
    17581 agacaggtcg gggtcttgcc cgtgtgggta cgtatcgcgg tgtccgtacg ggtcacctcc
    17641 gacttgaact tcgaccagga gaccgtccgc agatccacgt gcgaccaggt gtggttctgg
    17701 acgctgtggc cctcgcggtg cgcccgcttg gccgtcgccg ggttcgccgt cacattcgcg
    17761 ccggtctggt agaacgtcgc cttggcgccg tgctgcttga gcaggtcgag caccttgggg
    17821 gtgtggacgc ccggcccgtc gtcgaaggtc agatagacga ccttgggcgc gggcgccgcg
    17881 acggcggcgg gcgccgcgat catcaccgag cccgtcaggg ctccggccag gacgaccccc
    17941 gccagggccg tgcggctccg tcggtggccg gtggggtgcg agatggtgcg catgaaatgc
    18001 cctccccgtg agaacagttg tcgcgatgat cgccggaacg gcacgtggca agaggtgtgt
    18061 tgtgccgccc cccggcgtgc ccgctcacga tgatgcctgt tcagacaccg ttggtcgcac
    18121 gggggttgtg cttgattcag gaccggtaca cagacccgta ccggtcgtag ggatttgccc
    18181 cgccttcggc cggtgcgacc ctccccccga acggcccgga cccgccccgg gcgatcggcg
    18241 ggggcaccgg cgcgaccgag gacggaccgc gggagccggg ggaccggggg accgggggac
    18301 cgggggaccg ggggaccgga cgggggccgg gctaccggac cacccggacc ggacgggcct
    18361 cacccgtccc cccactgctc ccgtaccagc tcccgcagcg gcccgccggt gtcggcgagg
    18421 agtaccgacg gcgggccctc ggccacgatc cggcccccgt ccatcaccag cacccggtcc
    18481 gcgtccagca ccgtggacag ccggtgcgcg atgaccagcc gggtggcgtt cagggcccgg
    18541 gtgctgtcga tcacgacacg ctgggtggcg ttgtcgaggg cgctggtcgc ctcgtccagg
    18601 aacagcatcc tggggcggcg gatcagcgcg cgggcgatca tcagccgttg ccgctggccg
    18661 cccgagacgg tgcccgggcc cgcgaccatc gtgtgcatac ccatcggcat ccgccggatg
    18721 tcgtccgcga gtcccgccat cgtggccgcc tcccacgcct cctccacgct gaacgcctcg
    18781 gtgccccgga cacagtccag gaccgacccg gtgaacggct gcgcgtcctg gagcaccacc
    18841 ccgcactgcc gccgcaccgc cgccgtgtcc agcgcggcga ggtcctgccc gtcgtacagc
    18901 accgagccgg acagcggccg gtcgaagccg atgagcagcc gcagcagcgt cgacttgccg
    18961 cagccgctcg ggccgaccac cgccacgaac tcgcccggcc ggaccgcgaa cgacaccccg
    19021 tccaggaccg gcggaccctc gtcggtgtac cggaacgaca ggtcccgggc ctcgaccgcc
    19081 cccgccagca cccccggccg gacccggccc gcgcccacct ccggccgggc gtccagcacc
    19141 ggccggatct cctcgaacac cggccacgcg gcggccaccg acaccagcgc cccggtgagc
    19201 tgggtcgccg acatcagcgt cagggtcagc gcggtgctga acgtcaggaa gtcacccgcc
    19261 ggcatcgacc ccctggccgg acccgcgagc agcgcgaaca tcaccagcgt gcacaccggc
    19321 agatacagcg ccccgagcac cgccgacaca ttcctgatcc gtcccacccg ccgctggagc
    19381 tcccggctgt gggcgaactc ccgcgcccac gccgcgtacg cgtagtcctc cgccgccgcg
    19441 acccgcagct tgggcagccc ccggagggtc tggtacgccc ggtcgcccag cttgttcccg
    19501 agcgtcacca gcctgcgctg ccagcgcagt tgccacagcc ccagcccgag gaacgagcac
    19561 gcgatcacca ccagcgcacc cagtgcgacg ggcgccagcg ggcccccgta cacccacagc
    19621 agtacgacgt tcgccgcgcc gagggtgccc gcctggacga gtaccgggcc cacccccgac
    19681 agcagccgcc ggatggtgcc gacgccgagc gccgcgcccg ccagttcgcc ggtggcccgc
    19741 cgggtgaaga acccggtggg cagtctcagc agccggtccc acacggcggg ctggagcacg
    19801 ctctcgatcc tgccctccag ccgcagcacg gtgaggttct gcgtcagcag gaacgccgca
    19861 gtcaccaccc cgcccgtgat caccgcgaga cacagccgtc cgatcgcggc ccggtccccg
    19921 gccggtacca gtaccccgag gacatggccc gtcgcgatcg gcaccagcgc gcccagcacc
    19981 acggtcacca ccgcgcacag cgccagccgc cgcagatccg ccccgctgcc ccgcagacag
    20041 aaccgcagca gcccgagcgg acccagcggc cggtcgggca gcggccggta cagcatcacc
    20101 gcccggtcct cgaactcccc ggcgtcccgc gcaccgaccc gtaccccccg gcccggtccc
    20161 gcgccgaccg cctcgtagcc gccgcgccgc cacagcagcg ccaccggcgt cccgcccgcc
    20221 gaccggaacc ccaccagcgg acccatgtca cggcgccacc accggccgtc gaggcgcacc
    20281 cggcgggtcc gcacccccga atcgcgcgcg atccgttcca ccgggtcggt ccgctcgtcg
    20341 gggccggtgc ccggccgggg ccgcgcgacg gcgatcccgg ccgccgcgcc caccgcccgt
    20401 acggccgcgt acgcggcgtc cgtgccgccg ggaccccggg gtcggcgccg ctcccgggtc
    20461 ggcgcggctc cgtcggcgag cgcgtccacc agcgtccggt ccgcctccgc gcggaccgcc
    20521 tcacccgccc gtaccccggc cgccgcccgg tcctcgtggc cgcgctccag ctcctcgatc
    20581 cagcggtcca gcgcggtcag caaccgccgc tgctgctcca ccatccgccg ccacagcccc
    20641 gcgtcgacga gcagttcgcc cgcggcgcca ccggccgggt ccggcccgta cgcgaccgcg
    20701 cccggcggga cctccggcca cagcacggcg tccccggcgc cgccgtccgc cacgccgccg
    20761 tccgccacgg ggccgtcacc gagcggaccg gcgaagaggg tgccgagcgc acggccgacc
    20821 cccagcgcga acgcgtactc cagcgccccg gggtactccg tgcccgtccc cgccgccggc
    20881 catcctccgc ccaccggcca cggcagttcc cgcaggccga cgcggcgcag cgcgcacccc
    20941 cgcagcggac gggccaccag cgtgtgccgg ggaccgcccg ccggacccag cagcagcgtg
    21001 cccggcccca gccgccccag gaagtgccag tgccccggac ctgcggtgtc caccgcgaag
    21061 aggtccaccg ccccgtcctc caccagccac agcgtctgcg gtcccgccgc cgccagatcc
    21121 ggcggctccg cgtccggtac ccgcactccc agcgcgccga acgcgcccag caccacggcc
    21181 gcgtccccgg cccccgcgcc cgtcacgggc ggcgccgtca tctcagcgct ccgcggcgag
    21241 ttcggcgtac ggaccaccgg cggccagcag cgcgtcgtgc cggccgcgct ccaccacctc
    21301 gccgtgccgc agcaccagga tctcgtcgct gtcgcggacc gtgctcagcc ggtgcgcgat
    21361 caccacccgg gcgcagccgc gccgccgcag attgtccacc acgaggcgtt cggtcccgct
    21421 gtccagcgcg ctggtcacct cgtccatcac gagtacgctc ggccggcgca ccagcgcccg
    21481 cgccagttcc agccgctggc gctgcccgcc ggagaagttc cggccgtcct gctcgacccg
    21541 ggcgtccagc ccgcccggcc gccgcgtcac cacgtcgtac agctccgcgt cccgcagggc
    21601 ctccaccacc gcctcgtccg gcaccgacgg gtcccacagc gcgatgttgt cgcggaccgt
    21661 gccctcgaag aggaacacgt cctggtccac gaacgccacc gaggcggcga gcgtcccgcg
    21721 cgacagctcc ccgaccggct caccgtcgat ccggaccgtg ccctcccatg gtgtgtacag
    21781 ccccgagatc agccgtgaca ccgtcgactt gccgctgccc gaacctccca ccagcgccac
    21841 ctgccgcccc ggccccacct ccagcgagaa ccccttcagc aacggcgcgt ccagcgggct
    21901 gtacccgaac gtcacgtcct tcagctccac atggcccgcc agccgccggg gccccgccgc
    21961 gtcccggtcc gcacccgtac gccgcgcctc ggcggggaag ccctccacgt cccgcagccg
    22021 tgccacgtcc gccgcgaagt cctggatacg gcccgccacc gaacccagcc gggccagcgg
    22081 cgcggtgaag cgggtcacca gcgcctggaa cgccaccagc agccccaccg tcagcagccc
    22141 gtcgaccgcc cgcagccctc cgatccacag gatcagcgcg ctgttcagcg tggccagggt
    22201 cggcgccacc acccccagcc acgccgtggg caccccgagc cgctgctgtt cctccagcgt
    22261 caccgcgtgc tgccccgccc accgctggaa ccagccgtcc tccccgccgg tcgccttcat
    22321 cgtctcgatc atctggagcc ccgagtacga ggtgttgatc aaccgggccg cgtccgcccg
    22381 gagtttgcgc gtcccgtccg cccgcgcggc caccgcccag cgcagcgcgc ccacgttcag
    22441 cagggccacc gccaccccga gcagggtgag ctgcggatcg tacgaccaca tcagcgccgc
    22501 gtacagcagc accaccaccg cgtcgacccc ggccgccgac agatcccggg ccagggtctc
    22561 cgcgaccgcg tcgttcgact ggagccgctg caccagatcg gccggtccgc gctgcgcgaa
    22621 gaacgtcacc ggcagccgca gcagatgccg caggaaccgg gcgctggtca gcgtcgacga
    22681 caccagccgg ccccgcagca gattcccctg ctgcgtccac gtcagcaccc ctgtcagcag
    22741 caccgcgagc gccagcccgg tcagcagcgc ccccagcgac tccgtccgcc cgccgatcag
    22801 gaacagatcg aggtacgtcc ggctcagcgc gggcaccgcc gcgccgaccg cgaccagcag
    22861 cagactcgcc agcaccaccg cggtcgtcgt cgccgacgta cccgcgagcc gcgccgggag
    22921 cgcgcccgcc cacccggccc gccgcccgcc ccgccggaac cccggaccgg gctccatcac
    22981 cagcacgacc ccggtgaacg cggcgtcgaa ctcctccatc ggtacgaaac gccgcccccg
    23041 cgccggatcg ttgacgtaca cgcccgcccg gccgggaccg cgccgcgtcc cgtcgtacac
    23101 cacatagtgg ttgaactccc agaacagcac cgccggggcc gcgaccccgg ccagcgcggc
    23161 cgtgtccatc tgcatgccct tggccgtcag cccgtgccca cgggccgcct tgagcagatt
    23221 gctcgcccgc gacccgtccc gtgacacccc gcacgcgatc cgcagctcct ccagcggcac
    23281 atgccgcccg aagtgcccca gcaccatcgc cagacacgcc gcgccgcact ccaccgcctc
    23341 catctggagc acggtcgggg tgcgcaccgc gcgcggcgcc cgccgccggg gcgcccgctc
    23401 ggcggcccgg tgccgcgcgg acgcttcccc ggacccgctc cgtgtccggt gcctactcat
    23461 ggcagcagcc aatcgatcgg gcgctgggcg gggagccgta cggcgccgct cgcgcgggtc
    23521 atcgaccccg gcgggtacgg gggtcccggc ggcgccgacc agcggtaccc cgacctcgtc
    23581 gcggggtccc ggtccagccg cacctccacc gtgacgggca gcccccgccg ggtgaactcg
    23641 gcgccgagcc gcgcgtcccc gaggaacgcc ccgatccggc gggcgctctg cggggtccgg
    23701 cccacctcgc gcaccacccc gcccagcttc ccgtacctgc gcgcgggcac cgactccacc
    23761 gtcacctcca cccgcgcccc gaccgtcacg gccgcggccc ggtccgccgg tacgtacagc
    23821 agcgcgatca gcggttcgcc gtcccgcccg acccgttcga ccagggcgac ctcggccccg
    23881 gcggtgacca ccgcgccgat ggacacggcc agcgaggtga tccggcccgc cgcgaccgcg
    23941 cggacggccc ggtcgccgtc cgccgtccgc acccgcagca ccggggcccc ggcggcgagg
    24001 cgttcgccct cctccgcgac gaccgccgtg acctgcccgg ccaccgggct ctggaggaca
    24061 tgaccgccgt gcccatgggt gagcaccccg ggcgcgctca attcggacgg cacaccgccg
    24121 gtcaccgccc agccgcccga ggcggccagc acgagagcgc agaccgcgag cgcgagacgg
    24181 ccctgcgggc gggccagccg caccggcagg tcgagctcct cgggcgaccg ggccttggcc
    24241 agggcccgtt gacggaactg cacggcacct tcccctctcc acggcccgtc ggccggacac
    24301 agccgtgcgc cccgggccgg ggggccacgg ggcgcacggg cggttcagct cctcagagcc
    24361 cggcgaccag accggcgacc ggggcggtgc tcagccccga ggtgtcctcg acgccgccgg
    24421 tgaccgtgcc gagcgtcgcc gaaacggggg cgaccgagtc ggcggtggag gccaccgtgc
    24481 cgaggacgtc gccgacgagt ccgccggaca cgttgtccag gtcgctgtcg gagatctcgg
    24541 cggtctcgac ctggggggtg atgtccatga tgtgcgtgcc cttccgatgg atgtacgtga
    24601 gcgggatcgg ccggctcggg ggaatcccgc cggaccggcc cggcggccgt caactcccgt
    24661 gcgttccagg agcccttccg ggtgaccgcc gtctggcgca gatacaagca cgggggccgc
    24721 gcgggcggcc aacccgtcgt cccggggcca cccacgatgt ccaagggtgg tgcagacgcg
    24781 ctcaccgttc ggtgccgccg ccttcaccgg atgcccggaa acccccgccc cccgaaccgg
    24841 acactcccgc acacacctcg ccccgtcccg cgcgccccgc accccggctc gcacgcacgt
    24901 gcccaccccc ggcctcccat gtgcagatcc cgtacccacc ctcccagggg gcgcgggcga
    24961 aggcgttccg cgaggtcgcg cccccttcag accagcgaag cggacccgcc cgacggccgg
    25021 ggcgccgcgt acatcgcctc gatctccgcc gcgaacgcct cgacgaccgc accccgccgc
    25081 accttgaacg acggcgtcag caaccccccg cccaccgtga actccgcggg caggatgtgg
    25141 aacgcccgga tggactccgc cggggacacc ccggagttgg cccgcaccac ggcgcgctgg
    25201 accatcgccc gcaacgccgt gtcctccccg tccccgccgc cctggccggt cagcttgcgc
    25261 cagtgcgcca ccgccgccgg atcgagggtg atcagcgcgg cgagacaggg ctggtcgtcc
    25321 ccgacgacca cgcactgcga caccagcgga tcgtcccgca cccgctcctc cagggcgagc
    25381 ggcgccaccg tccggccggt actggtcacg atgagatcgt tcttgcgccc ggtgatgacg
    25441 agatacccgt cgtcgtccag gaacccgagg tcccccgtac cgaaccagcc cccgcgcagg
    25501 gcggtacggg acgcccggac gtcgttcaga tagccgagga agacattgtc gccccgcacc
    25561 cagatctcgc cgtcagcggc gatgtgcagc gaatcacccg gcaacggttt gcccaccgtg
    25621 ccgaacttga ccgcgcccgg cggctgcgcg gcgcagccgc cggaggtctc cgtcagcccg
    25681 tacccgtcgt acacggtgat cccggcgccc gcgaagaaca gccccagccg gcggcgcagc
    25741 gtggacccgc cggacaccgc gcagcgcgcc cggccgccga agaccgccct gatccgcgcg
    25801 tacaccgtgt ggtcgtacag cgcgtgctgc atccgcagcc cggcccccgg gccggtcccc
    25861 tccccgtgcc gttcccgctc caccgcctcc gcgtaccgca ccgcgacgga caccgcccgg
    25921 tcgaacacgg ccgccttgcc gccgagttcg gcgcggcggc gggcctgccg gaagatccgc
    25981 tcgaagacat ggggcacggc gatcacacag ctcggccgga agctcgccag cgacggcagc
    26041 agcgccccgg gcctcatgtc cggctgatgg gcgagccgga caccccggcg gacggcggcg
    26101 acggcgatca tcagcccgca cacatgggcc atcggcagga acgtcagcag cgaacggtcc
    26161 ccgtcctcgg cggtcagcac ctcgccccag cccccgacga gggtgtccgt cccgtacgcg
    26221 aggttgcggt gggtgagcag acagccgcgc ggctgcgggg acgtcgtacc ggaggtgtgc
    26281 acgatcgcgg cgatctgctc ggggcggacc gccgcccggc agcggtggac ctcctcgtcg
    26341 ggcacctgag cgccctccgc caccagctgc tccacacagc cggcgtccag ctgccagatc
    26401 cgggagaaca gcggcagccc gtcgcacacc gcggccacgg tcatcgcatg gccctcgtcc
    26461 tccacgacga ccgccgagac ctgcgtgtca cgcaggatcc agcgcacctg gtccgtggac
    26521 gacgtggggt acacgggcac gacccgcgcc cccacggtcc acagggcgaa cgcgaacagc
    26581 gtccactcgt agcgggtgcg ggacatcagg gcgacccggt caccgaaccg gatgccgccc
    26641 gcgagcaggc ccttggcgac gcccatgacc tcgtcgcgga acccggcggc cgtcagcggg
    26701 acccacacac cgcccggccg gtcaccgccc agggacatcg ccacggtgtc cggttcccgc
    26761 cgggcccggt cgaagacctc gtccgcgagt ccgcccgcgg ccagtggctc caccagacgc
    26821 ggcacgctga tctcgcgcat cgcggccccc ttcctcccgt cccgccgtgc ggacggcagc
    26881 acgggcacgg gcacgggaca gcggcattcg acgcgaaccg ctcgtcacgg acgggactgc
    26941 ctagagggtg acatggaagg cacgcgccgc gcgcgtgatc acctgatttg gctccggcgc
    27001 gcccgctcac cgttcgtccg tccgccccgc cgccgtcccg gccgcgctca gtggtgtccg
    27061 gagccgaggg ccgtggccag ttcccggtcg gtcagcggcg gccccgccag cggcggcagc
    27121 cggggtccgc gcagcaccgc gaacaccacc tcgggccgca ccagcgcggt catcggcgcc
    27181 gacagcgtca tcacgtccag cagcgccttg gcgaccaggg gccgggcgct cgccgtccgc
    27241 atcagccggt cgacatagcg gcgcgccgcc ttcgcggacg gcccggggcg gcgcccgatc
    27301 gagcccgggt acaggatgtc ctgggcggtc gccagatccc aggccaccga gaccggccgg
    27361 gccacggccc gttgggcgcg ccgcgcctgg cccggcgtcc cgagcccctc ggcgtccacg
    27421 agctgccgca gcgccagcgc cccctcggcg gccaccgaca tcccgtgccc gtacacgggg
    27481 ttgtacgtgg cgaccgcgtc ccccagcacc aggaacccgt ccggccacgg ggcgacccgt
    27541 tcgaagaagc ggcggcggtt gacggtgctg cgggtcaccc gtaccccggt gagcggctcg
    27601 gcgcgggcta tcagttctcc caccaccgga tggcgcaccg tgcgcgcgaa cggctcgaag
    27661 ccctccgggg acgggcccgg ttcaccgccc cgggtaccgg acagtgtcac gagccaccgc
    27721 tcaccctcta tgggcacgat cgtcgtcgtc cggcccggcc gcgcctcgcg ggcgtcggcc
    27781 tggacgttca ccaccgggaa gtcctcggtc cccggcggcg cccggaagat ccgggaggcg
    27841 tacaccagcc ccgagtcgac ctcctcctcc gccgcccggg gcaccccgag cgcggccagc
    27901 tgggccaccg cccgtgagcc ccggcccgag gcgtccacca ccagatccgc ggcgaggaat
    27961 cgttcctccg ccccctgacc cgggccgacc cgcagccgta ccccggtgac gcggcgcgcg
    28021 tcgccctcca gggcgagcag ttcggagtgc tccaggacgg tcaccgccgg gtcctcggcg
    28081 acgctctgcc ggatgcccca gtccagcaga tcgcgacttg ccgcgatcat gaactggagc
    28141 tcggggaacc ggcgtatcca gccgctcggc tgcatcgaca ccagcccggt cggcagcgct
    28201 atccggcggg ccccggccgc cagccaccgt gcggtgaccc cgggcagcag ctcctccagc
    28261 gcgcgcgccc cgcccgacca cagcagatgg gcgtgccggg cctgcggaag ccccttgcgt
    28321 gattcgggac cctccggcag ggtgtcccgc tccaccaggg tgacccgggc gtggccccgc
    28381 agcgcggcgg ccgccgccag gcccgcgact cccgcgccga tcaccacggc atggcggtgc
    28441 ggggtgtccc gggcggctcc ggcggatcta tcggatgggc tcatgggtac cgctttctga
    28501 ccgggcgacg gccgtacggg ccgccgcgac gacgggggag tggcgcagcg ccagggacat
    28561 ccggaccagg tcacgggggc cctcaccgga gacggcggtg tccggcggcc cgtccggccg
    28621 cgccagcgcc gtcccctccg gatcggccgc gcgcgcccgt accgcggcgg tcaccatcgc
    28681 cgcgtcggcg acggcccgcg cctgcgccgg accgttcccg gacgcgacgg cggcggcgtg
    28741 cgcgcgggcg tggacccggc tgtcgaagta cgggtacagg ctgagcatcc cgtcatggat
    28801 gtcggactcg cgctgggtca ccaggagatc cgccgacggc caccaggaga tccgcgacgg
    28861 tgcgacgccg tgcggcccga gtccgcgcag ctcgcgccag agcgggccga gcctgcggta
    28921 ggtcgaccag acggtgacct gctccccgag ccgctggaac gccagcggca gacagaaccc
    28981 gatggcgctg aacagggccg ccgccgaggc cagcaggggc gccgtctcgg agctgagcca
    29041 gtcgaggtca tggcccgccc agcgcgcgaa caccgccgtg aacttggtcg ccgcgtacga
    29101 caggttgaac agatacccga cggcgatggc ggacagcccc gcgcgcagca gcccccgtac
    29161 ctggagcgac cagcgcaggc acagataggc catggcgacg cccgcgaccg tgagcccggt
    29221 caggtacagc acgatcatct cgcggatgta cggggtgttg gcgtagtagg tgtccaggtc
    29281 gcgcagccgt tccaccggcg cgtcaccgag cgcgaacagc accacgaggg ccacgctcac
    29341 cgcggtgtac ccggcgatcc agcggcgcga gacccgccgg gtcacctcgg gcggtccgcc
    29401 gcgccagttg accatcagca ccagacagga ggcgctgaac gcggacagca gggcgtacac
    29461 gagcggcccg gagatgttgg gcacccccgt gatccggttg acctgcgcga tcgtcggcgg
    29521 cgcggagaag aagaacaccg aggtgccgag cgcgagcagc gcgcacaccg agcgcagcag
    29581 cggatcgcgc cactcccgca gcagggaggg gaacttgaag gcgagcgcga tgcccgtcgc
    29641 cgcggcgggc agatagtagt cggggccgtt cacgcctcag ccttgcggcc tgcgatagcc
    29701 cagggacgcc tcgatacggg cggtcagctc gtcacgcggg gcctgcccgc ggcccgccgg
    29761 gccggctgtc cgggagcggc acttgctggc gagcagcagc ccgaagctct cggcctcctc
    29821 ctcctcgacg gcgtgcgaac ggctgcgggc ggcgaccctg cggaccgtgt cctggagatc
    29881 gacgccaccg gcgagcagcc gggcggccac gcccgtgccc gccgcgtcca cgtgccgggt
    29941 gctgtgtccg gccgtcatgt gccacagctc atgcccgagg atgaccaact ggtggtcggg
    30001 cgcggtgcgt tcctcgatca cgatgaggtc ctggtcggcc atgtccagcc agaggccgct
    30061 cgccgtgccc ggcgggaacg cggccatccg gtggttgacc ggccgaccgc gccgccggct
    30121 catcgtcgcg cacagcgcgc cgatcagggc gccgggggtg tcgggtatct cggggggcag
    30181 tccggcgatg agttcgccgc acaacttgcg catgtccttg gtgacccgcg cgcgcatcag
    30241 ggctccgtgg ggccgtgggg cggcttgacg ctctccagca gcatgtccag ccactccgtg
    30301 accttgtcgc ggtgcttgtc ggtggggagt tgggcggcgc gccaggcgat accgcgcacc
    30361 ccgtgattct gcaacagctg ttccagagcg tcgtccatcg cgtcccgcga cgggttcccg
    30421 ggatccgcgc ccggcgcggt gcccggcggc gcgggcggcg cgggcggcac ggcgcggtcc
    30481 tgggcggcgg cccactggag cagttcctgc tcggtgagct ggagcgcgga gaccagcgcg
    30541 tcggcgtcct cggcggtcag gaaccccgcg tggacgccga agaagcgctg gatggccgcg
    30601 cagtgctcca tcgtgggccg ccggtcgccg ttgatgaggg cgccggcctg ctgccgtgac
    30661 atcccggcgc cgtcggcgat ctcctgctgg gtccagcggc ggccgttcgg tttcagccgt
    30721 gttctgcgca gcaggtcgaa ccgctggagg aaccgggcct ggagatcggg ctcaccgccc
    30781 gtgcgcccgg tcagcagatc cctgaccac
//
