LOCUS       NZ_LWLE01000037        22226 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0281 scaffold8, whole genome shotgun sequence.
ACCESSION   NZ_LWLE01000037
VERSION     NZ_LWLE01000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0281
  ORGANISM  Streptomyces sp. TSRI0281
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 443716)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443716)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905125.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,600
            CDSs (total)                      :: 8,518
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 82
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 345
            CDSs (without protein)            :: 343
            Pseudo Genes (ambiguous residues) :: 0 of 345
            Pseudo Genes (frameshifted)       :: 151 of 345
            Pseudo Genes (incomplete)         :: 273 of 345
            Pseudo Genes (internal stop)      :: 33 of 345
            Pseudo Genes (multiple problems)  :: 102 of 345
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:13:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 147729
            Orig. end                         :: 169955
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWLE01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22226
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22226
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22226
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12226](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12226
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    371..384
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            complement(421..1356)
                     /locus_tag="A6A29_RS39630"
                     /old_locus_tag="A6A29_21985"
     CDS             complement(421..1356)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="A6A29_RS39630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_21985"
                     /product="cytochrome P450"
                     /protein_id="WP_241838821.1"
                     /sec_met_domain="p450 (E-value: 4.4e-12, bitscore: 40.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSTRAAAPRSPGRSPPAGSPPCASSSSAPPTGCWAAERNGGRTD
                     LLGEFAYPLSTHVICELVGVDERDRDQVCAWIRDFAYGDGSRTGEALVGIVEYCKELIA
                     RRRAASAEDLISALVEGARESEGPLSDDELAGIVFLLIDTGITPPALFLAHGALALLDH
                     PVQAARLHAEPELLRRAVPELLRHITLVRIGATLYAEEDFDFAGTPLKTGEAVTVALLA
                     VDQDSEEYGESAEQLDITREFGRGDGHLAFGHGAHYCIGAALGRLVTSVVLDRLFVSRD
                     SLRLAVAREELEFGHWPADGFHLLSLPVTL"
     gene            complement(1881..2728)
                     /locus_tag="A6A29_RS39635"
                     /old_locus_tag="A6A29_21990"
                     /pseudo=""
     CDS             complement(1881..2728)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541116.1"
                     /locus_tag="A6A29_RS39635"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_21990"
                     /product="MerR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSNAREHEPAFTGEGAEPPGPDGLTVGRTAALVGVSVKTLHHWD
                     AIGLVSPSERTWAGYRVYSGDDIARIHRVLVYRELGSPLAEIGRVLDDPDADARDHLRR
                     QRAQLVERIARLQKMVGAVDRMMEASRPGMRLTPQEQVDIFGADWQPAWAEQAEARWGD
                     SAQWTQYAERAAGMTPQDWKAVAAANDALNADLATAKYAGVAPGSDEANALAERHRALI
                     SGYFDCTHSMQACMGRMYVGDAGYADAYDALAPGLTLWLRDVSSRTPQSTASTRNPRGG
                     S"
     gene            complement(2933..3820)
                     /locus_tag="A6A29_RS39640"
                     /old_locus_tag="A6A29_21995"
     CDS             complement(2933..3820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966108.1"
                     /locus_tag="A6A29_RS39640"
                     /note="predicted Zn-dependent protease with a strongly
                     conserved HExxH motif; predicted Zn-dependent protease with
                     a strongly conserved HExxH motif; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="A6A29_21995"
                     /product="DUF2268 domain-containing putative Zn-dependent
                     protease"
                     /protein_id="WP_073728394.1"
                     /transl_table=11
                     /translation="MKIVVHDTASAMFDLLRRPLEERPDALRELLSPLQSAMSAVGDLD
                     MVKMHQMGSGFRIDREDPRYLAALSRMREAGVWNQIENCLAAAWERLSGEVPGIRSAET
                     VHVVLVLGDPDDDLLTVRNAGYFGMGGIPGAIQLTMWPTATSLAKIGYAAAHELHHNVR
                     YANVVWNPLTVTVGEQVVAEGLAEAFVRELAGERAMGPWATALSGAELDDVHEKLSAGI
                     DVAGMQNLPAYVYGDATARHLGQQPVGLPDFAGYAGGLRIVDAHLAASGLTAARSTALP
                     ARDILTNAGVATGA"
     gene            complement(3940..4077)
                     /locus_tag="A6A29_RS45630"
     CDS             complement(3940..4077)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A29_RS45630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158074507.1"
                     /transl_table=11
                     /translation="MAEALAADELAGIDQFLLELLVRGEGDQRLIGRGVGGSGVPGGGR
                     "
     gene            complement(4409..4936)
                     /locus_tag="A6A29_RS39650"
                     /old_locus_tag="A6A29_22005"
     CDS             complement(4409..4936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158294.1"
                     /locus_tag="A6A29_RS39650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22005"
                     /product="DinB family protein"
                     /protein_id="WP_073728886.1"
                     /transl_table=11
                     /translation="MTWTAPPVERSNQLGDLGTVTERRMLEGWLGRHRETLLAKCAGLQ
                     QAQLARTTVEPSNLTLLGLVRHMAEMERWWFRRSFAGEAIGDVFAGPSDGDEGLDGVHA
                     ADAQRDFGLLRAEVEACDVAAAGHDLDETFVSSRGVSLSLRWVYVLMIQEYARHNGHAD
                     FLRERTDGATGD"
     misc_feature    5138..5147
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            5245..6261
                     /locus_tag="A6A29_RS39655"
                     /old_locus_tag="A6A29_22010"
     CDS             5245..6261
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010637628.1"
                     /locus_tag="A6A29_RS39655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22010"
                     /product="S41 family peptidase"
                     /protein_id="WP_073728398.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 1.1e-20, bitscore:
                     68.4, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSTRPRRPGFAEAALVSVLLATAGCAGGTGTDPGGGMAPKART
                     YLTSALDVMEKRSLVTADVDWPKVRRDAFTRAESARTPAGTYASIRRALRDLGDRHSTF
                     FDPEEASQALNTPTDDLMLPEGRRLPGGIGYLMLPPVPSARVAAPYVRSARSTVGGMDA
                     QGACGWVVDLRSNSGGDMWGPLASVGPILGDGTVGAAVYADGKRSPWTIDNGTPRQHSD
                     DWGPAESLARPAPPVAVLTSRRTASAAEAVTIAFRGRPDTRTFGEATAGVPTANAPYRL
                     SDGALVILTVAREADRTGHVYDGPITPDVEVPETRGDDQALEAATDWLKTRKACRTP"
     gene            6431..7072
                     /locus_tag="A6A29_RS39660"
                     /old_locus_tag="A6A29_22015"
     CDS             6431..7072
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950308.1"
                     /locus_tag="A6A29_RS39660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22015"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_073728400.1"
                     /transl_table=11
                     /translation="MRTLYVVTHPEATHHVEKVVGGWHDSRLTPTGVRAAASIAQALRA
                     VVPDDAEVELYSSDLRRTRQTAEEVAELFGVQPVLDPRLREKSYGEAEGKPQEWLDRRF
                     VPPPAVGERMDHDEGVAGSETKAVWAQRIYAAMDEILRSPCEHQIIVTHGGSLTCVVAS
                     WIRMPLESAGYAGFRAPSGSITTLHEDDFFHNRHVVSLGDTRHLDPAEAG"
     gene            7035..7568
                     /locus_tag="A6A29_RS45635"
                     /old_locus_tag="A6A29_22020"
     CDS             7035..7568
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.4"
                     /locus_tag="A6A29_RS45635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22020"
                     /product="hypothetical protein"
                     /protein_id="WP_274535858.1"
                     /transl_table=11
                     /translation="MTPVISIPPKPADLNPARDILSWNPMAAALLIDFSGIPERNRNYA
                     WMVFSDPAMKVIHADWKNTAHSCVAMLRTEAGRNSQDPRMATLVGELSLRDDGFRRRRG
                     GRHIATRNRGSKVLRDPVAGELALDRDALACANDPDQQLVVWTAEPGTASHDALRILAS
                     WTADTQGAVSRTTD"
     gene            7785..9287
                     /locus_tag="A6A29_RS39670"
                     /old_locus_tag="A6A29_22025"
     CDS             7785..9287
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (136-479). E-value:
                     3.5e-22. Score: 71.1. Matches aSDomain:
                     nrpspksdomains_A6A29_RS39670_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003954963.1"
                     /locus_tag="A6A29_RS39670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22025"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_073728404.1"
                     /sec_met_domain="PF00561 (E-value: 1.8e-26, bitscore: 87.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSMRVNTNPNPHPRRGILSALLALSASAALAVPGTATAQEPAG
                     ATAPAPPISWGPCPKADPPYPDPSPKAQCATVKVPLDWSKPTGPKIGIFVARYRATGPA
                     RRIGVLMSNPGGPGAPGADDALYADDPVGGYSPAMLQRFDMIGFDPRGVGRSQGARCDE
                     TINDPVPARPRDAAGFARLRTLNGRLADSCLKRTGPLAAHMDGESVARDMDAIRAALGE
                     RRISFLGHSYGTFLGERYARLFPGNLRALALDSAMDPDRPDAERYLTDGSVTLNSTLEK
                     LAAWCAEDAACALKDQELTAVTDQLFARADAGTLLEPGPKGPTRTKVDADRLSDFLTGE
                     LRVWNPEGTARQLAALHTGKGEVRWTSSSTDPAAQLVLCRDYDFRIRDYAQYRAIRQRV
                     AKAAPHVRYNTQALDLVLGCQGWTMPPKPRPARAEGDLPPVLVVNATHDLATPLTGARR
                     MTNAFPKASLFTMDLVGHWLYRRGAPEEAMRVIDTYLTGLKG"
     aSDomain        8193..9221
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS39670_Abhydrolase_1.1"
                     /evalue="3.50E-22"
                     /label="A6A29_RS39670_Abhydrolase_1.1"
                     /locus_tag="A6A29_RS39670"
                     /protein_end="479"
                     /protein_start="136"
                     /score="71.1"
                     /tool="antismash"
                     /translation="PAMLQRFDMIGFDPRGVGRSQGARCDETINDPVPARPRDAAGFAR
                     LRTLNGRLADSCLKRTGPLAAHMDGESVARDMDAIRAALGERRISFLGHSYGTFLGERY
                     ARLFPGNLRALALDSAMDPDRPDAERYLTDGSVTLNSTLEKLAAWCAEDAACALKDQEL
                     TAVTDQLFARADAGTLLEPGPKGPTRTKVDADRLSDFLTGELRVWNPEGTARQLAALHT
                     GKGEVRWTSSSTDPAAQLVLCRDYDFRIRDYAQYRAIRQRVAKAAPHVRYNTQALDLVL
                     GCQGWTMPPKPRPARAEGDLPPVLVVNATHDLATPLTGARRMTNAFPKASLFTMDLVGH
                     WLY"
     misc_feature    9644..9657
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.51"
                     /tool="antismash"
     misc_feature    9646..9662
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    complement(9667..9679)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            10001..12226
                     /locus_tag="A6A29_RS39675"
                     /old_locus_tag="A6A29_22030"
     CDS             10001..12226
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="A6A29_RS39675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22030"
                     /product="cytochrome P450"
                     /protein_id="WP_198953565.1"
                     /sec_met_domain="T1TS (E-value: 2e-48, bitscore: 160.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 7.5e-22, bitscore: 72.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVSSPSLIGSEPFAIPRVRLPFGTPGERPDSEVLRAHAIRWGED
                     FGLIGPRGGARLAETSLLGLGVALTGTAPRAGATVLMDWFLWAVVLDDRVDDGPWAEDG
                     ALDRFSAAVDAITRGQEGRAGVHDPMLTVLIDDLWPRTGRLADEAWLERLRGHLLHHLD
                     AQRDLVRMRETAADIGSEEYVRIRRHTFGAPLFFDLIEAADGLVLPADPCGQGCWPVLR
                     DRAADVVSWTNDIHSVAKDVVLGERFNLVTVLAQERSLTPQAAVDAAHEMLATAVSDFT
                     AVKRRHLGHADLPEADRPDVARAAGRLEQVMTASVDWHRTTSRYHLQSGIPAQDRHGSV
                     RTGEATPTLKSRQFETDPYPLYERLRTAFPLAYDEPTDTWLLSRHADVRTALTDQRFTN
                     ANYTWQITPLLGHSIVSMDGREHTAHRALLTPEFRSRALAVMHDSITEVATSLVERLRG
                     RDTADLITEFTTPLPVQVIARLLGLPTDTPEQVARLRNWTKVGFSYLGNYRQDPGLLTY
                     GLASRDDFYAYLQPYLDARRTQPGNDLISVMFDSVVDEQPLSEEYIRGCCAILLTAGSE
                     TSNAGLANLIVNVLDEPGVRDAVRRDPALVDHALTETLRRDAPMQLVLRQTSEAVELPS
                     GTVPAGATVACLIGAANRDPERFRLPDEFDLHRTDSIDREYSAASSHVAFGAGRHFCLG
                     SHLVRAELTAGLRILLDAFPDLRWAPGFTPRPTGFVKRCPPRLDVTL"
     misc_feature    complement(10029..10047)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.88"
                     /tool="antismash"
     gene            12223..13050
                     /locus_tag="A6A29_RS39680"
                     /old_locus_tag="A6A29_22035"
     CDS             12223..13050
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003956088.1"
                     /locus_tag="A6A29_RS39680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22035"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_241838822.1"
                     /transl_table=11
                     /translation="MTTRVEPASDRPALPSPCGYGSSYVAHHTPGERSRLGTLEAAFDP
                     ATIQALVGLSLPEAAVCLELGAGAGSIAAWLAAHRPRGHIVATDTDIRFLRFQPGAPVR
                     VLRHDVVTEDFPDASFDLVHARALLCHLPDHDRILERAARWVRPGGWLVVEDLTVQPVD
                     ASPHPILRKVTRAGEVLFRTTVGTDLRWAQTLPQRLRGIGLHDVRARTTPGTIGDGGAT
                     DAFWTATFEQSLPAHLAAGTLRHEDIEAMRALHRAPGFTDTAVAMVSAWGRKT"
     misc_feature    12616..12618
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13086..14267
                     /locus_tag="A6A29_RS39685"
                     /old_locus_tag="A6A29_22040"
     CDS             13086..14267
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014998.4"
                     /locus_tag="A6A29_RS39685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22040"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_073728406.1"
                     /transl_table=11
                     /translation="MGPAPSGHGSNLLDRTYLSYSGRDQPVITLAMDYRGTPPALDLLV
                     GRVKERAACIPRLRAGTAALGSNVLGAAVSDIDKETGRISRSPFELVGGLPLWDVRLLE
                     GKPGSAFFRVCFRAHHGFLDGVGATHAATALLPDEPGEGARLHPPTSPGVRGMARVLKD
                     MACSLVHRSAWSPPHSAAPGHTDGRSVYRDVPVAVLRTYADTYGVSVNDVSLAALGLAF
                     GDWQRDRVPAESRRDIVASVAMSTRTPQERHHAGNRLGVYRLKFPHRIESFAEAVSLVC
                     RQTAKVRDTRQRDALRTALGAPVPPKLGVRAFSSLLNPQATPLVISSVSLPENHTLFGA
                     DLCAASMTLNVFANFPAYISFTRTPENVRCAAVSDPARNSVLAVPEHWANCLA"
     gene            14443..15258
                     /locus_tag="A6A29_RS39690"
                     /old_locus_tag="A6A29_22045"
     CDS             14443..15258
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330260.1"
                     /locus_tag="A6A29_RS39690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22045"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_073728408.1"
                     /transl_table=11
                     /translation="MSDHAMTPGPAVHQKIDTSVPHSARIWNYWLGGKDHYPVDEAAGD
                     AYSAVFPGIVTIARSSRAFLRRTITYLVNEAGIRQFLDVGTGLPTENNTHEVAQRLAPE
                     SRIVYVDHDPMVLAHARALLTSTPEGATAYVDAELSDPDRILAAAAKTLDLTRPTALIL
                     SNILGHVADYDQARTTVTRLMNGLPSGSYLSINDGSRGTDADYEQAQDAYNETGAVPYF
                     LRPVDRIVAYFDGLELLDPGVVSVPLWRPEPASTAPGPIGEHGGLARKP"
     gene            complement(15388..16488)
                     /locus_tag="A6A29_RS39695"
                     /old_locus_tag="A6A29_22050"
     CDS             complement(15388..16488)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031720.1"
                     /locus_tag="A6A29_RS39695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22050"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_073728410.1"
                     /transl_table=11
                     /translation="MQRKRPAVAVLLAATLTGAFAPAAVAHQPNPVQRQLDLLVDRGGV
                     PGALAYDGRATRTAGVSDMVSGRPMADAQGRFRLASNTKAFTAAAVMKLVADGRIRLDD
                     RAGTYVPQLSERDITVRQLLKQTSGLPEYSALVDWTRPGTAEDYLALALKEKPVFEPGA
                     DWGYSNTNYLVLGMVIDRTSGVGFRTYIERTILRPLHLDDTYWPAPGELTLRGPHARNY
                     GVHPARPEAGRVDVTELPGYEFGASGGLVSTPEDLNTFWDGLFGGRLLPDWALRLMTHD
                     TTAVGNRDVYPAGSRYGYGVASIPLSCGGVYWGHGGDLPGDSVGGGRATGHRGTVTVYT
                     TTWAAEGENLRRLQGAVDAALCARGR"
     gene            complement(16723..18000)
                     /locus_tag="A6A29_RS39700"
                     /old_locus_tag="A6A29_22055"
     CDS             complement(16723..18000)
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538620.1"
                     /locus_tag="A6A29_RS39700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22055"
                     /product="amidohydrolase"
                     /protein_id="WP_079183231.1"
                     /transl_table=11
                     /translation="MSDTDSAADSAPDTTAGSPLLTRLPDVRDGLADLYRDLHKHPELS
                     FAETRTAGIVAERLRKLGLRVTTGIGRTGVVGVLANGDGPHVLLRADFDALPVTEQTGL
                     PYASTADGVMHACGHDMHVTCLLGTLDLLADGRAHWSGTITAVFQPAEEIGQGASAMVD
                     DGLFDRFGTPDVVLGQHVGPFPAGTVGCHPGPALAAADALAVTMYGKGAHGSRPEAAID
                     PVVMAASTVMRLQTVVSREIAGGDTAVVTVGALNAGTKDNIIPDTAELRLNIRTYTDEV
                     RARVLAAVKRIVRAEAEASGATRSPDIDPIAAFPVLVNDEAAVRRTVTAFRGHFGAQRV
                     FDPGPVTGSEDCGIFGTASGAPVCYWFFGGTAPDSYRKAAAAGTTDRDIPSNHSPHFAP
                     VVEPTLSTGVEAMTTAALTWLSSGKR"
     gene            complement(18064..18522)
                     /locus_tag="A6A29_RS39705"
                     /old_locus_tag="A6A29_22060"
     CDS             complement(18064..18522)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015423.4"
                     /locus_tag="A6A29_RS39705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22060"
                     /product="TRIC cation channel family protein"
                     /protein_id="WP_073728414.1"
                     /transl_table=11
                     /translation="MGHVPAALTNSSYLVLCLIAGIIGHHLAYDRGQLLREGLFQFVTS
                     FALPWYAIVGAQTGVEVGLPVLGSLALAVVGPTAGRFLIDVSCGVPPKQFRGEWFVAIA
                     ALTGAVWIAPDQWDFPARQAPRPPTVGVQLLAVSPVRLPSRDSASPLS"
     gene            complement(18901..20730)
                     /locus_tag="A6A29_RS39710"
                     /old_locus_tag="A6A29_22065"
     CDS             complement(18901..20730)
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018529493.1"
                     /locus_tag="A6A29_RS39710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22065"
                     /product="alkyl sulfatase dimerization domain-containing
                     protein"
                     /protein_id="WP_073728416.1"
                     /transl_table=11
                     /translation="MTDLDYADRSDFEDAERGFVAALAPAVVRTDDGRMIWDGDAYAFL
                     DEECPDTAHPSLWRQSRLCNKQGLFEVTEGIYQVRNLDLSNMTLVEGDTGVIVIDPLIS
                     AETAVAALALYREHRGDRQVTGLIYTHSHGDHFGGSLGVLPHGHAPVPVIAPAGFLEHA
                     VAENVYAGGAMTRRAVYMYGAELDKGPAGQISAGLGMTTSTGTITLIPPTLDITRTGQE
                     ETVDGVRIIFQMTPGTEAPSEMNFYFPDRRALCMAENATHNMHNILTLRGAVVRDTRIW
                     AHYLNETIALYGDRAEVAFASHHWPTWGKDRIVDHLAGQRDMWAYMHDQTLRMTNQGLT
                     GSEIAERIELPPALAGRWANRGYYGSLSHNVKAIYQRYMGWFDGNPAHLWEHPPTEQAT
                     RFAADYGGVAALVAKGEEYAASGDLRFAATLLGHAVFAAPRDTAAKEALASVYEKLGHG
                     SENGTWRNFYLMGAQELRGSVAHTSLETTNPEMAMALTVDMLIDSLAIRIDGPRAWTKK
                     LAMAWHVTDESRTWHLLLSNGALTYRSTDGAPDAHGSAPAADLTLTLTKRHLLGVLAGA
                     GLDDVKVQGDPQVFATLASLLDTPDPDFAIVTP"
     gene            21011..21601
                     /locus_tag="A6A29_RS39715"
                     /old_locus_tag="A6A29_22070"
     CDS             21011..21601
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="A6A29_RS39715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_22070"
                     /product="VOC family protein"
                     /protein_id="WP_073728418.1"
                     /transl_table=11
                     /translation="MTPRNTEFELGGINHLALVCADMRRTVDFYSGLLGMPLIKTIELP
                     GGSGQHFFFDCGGGDCVAFFWFADAPDGVPGISAPVSLPGQGEFLSAVGSMNHVAFHVP
                     PERFDEYRARLVAKGVEVSPVMNHDDSPTTVAARLQEGVYVRSFYFQDPDGILLEFACW
                     IKQPTGEPHNTTDEPRTAADRTPRTPVPASVPA"
ORIGIN
        1 ttcggcacac gcgaatgctc cacctgttcg aatgcgcaac gcgagcaggc gcgccgaaac
       61 atctcataac gcacaaaacc cggcacatcc actgccagtc agctttcagg gcaccactcc
      121 atgcagcacc cgacgccggt cggtcggcgg tggagaactc gttcgccgga gagaccgcca
      181 gaccggcccg cgaccgtacg gggacggggt gcggctcatc gccctcgtcg gccggttccg
      241 ctgcctgcgc agtttccggc cgacgatgtc ctccacccgc tcccggcagg ccgccgagga
      301 cgccgacagc gcggcatacg cctacccggt ttcggggtac gccgccctgg cgggacgaac
      361 tggggcccgt ggcactgtcg ttgctggccg agcggacagg gacagggcga aggagatctc
      421 tcacagggtg accggcaggc tcagcaggtg gaagccgtcg gccggccagt ggccgaactc
      481 cagttcctcg cgggcgactg cgagccggag gctgtcgcgg ctgacgaaca gccggtccag
      541 gacgacagag gtgacgagcc tgccgagcgc ggcgccgatg cagtagtgcg cgccgtgccc
      601 gaaggccagg tggccgtcgc cccggccgaa ctcgcgcgtg atgtcgagct gttcggcgct
      661 ctccccgtac tcctcggagt cctggtcgac ggcgagcagg gccaccgtca cggcctcgcc
      721 cgtcttcaag ggggtccccg cgaagtcgaa gtcctcctcg gcgtacagcg tggcaccgat
      781 ccgtacgagg gtgatgtgcc gcaggagttc gggcacggcc cgccggagca gttcgggctc
      841 ggcatggagc ctggccgcct gcacggggtg gtcgagcagc gcgagcgcgc cgtgggcgag
      901 gaagagcgcg ggcggggtga taccggtatc gatgagcagg aagacaatgc cggccagttc
      961 gtcgtcgctg agcgggccct cgctctcccg ggccccttcg acgagagcgg agatcaggtc
     1021 ctcggcggag gcggccctgc ggcgggcgat gagctccttg cagtactcca cgatcccgac
     1081 cagcgcctcg cccgtacggc ttccgtcgcc gtacgcgaag tcgcggatcc acgcgcagac
     1141 ctggtcgcgg tcccgctcgt cgacaccgac gagttcgcag atgacatggg tgctgagggg
     1201 gtacgcgaac tccccgagca gatccgtacg gccgccgttc cgctccgccg cccagcagcc
     1261 cgtcggcggt gcgctcgacg aactcgcgca gggcggcgat cctgcgggcg gtgaacgccc
     1321 tggtgagcgg ggcgcggcgg cgcgcgtgct cctcaccgtc gaagagggcg agatgtccgg
     1381 cgaagtactt cacgtattcg gcgggcaggc cggcggaggc ggcatccatc aactcgtcct
     1441 gcgggccggc ctcttcgcgt tcgctcggta tcgccccgcg gtcagggacg agccgcggct
     1501 ccgtgagagc ggccttgacg tcggcgtacc gggtgacgag ccggacgggg gtccggaggc
     1561 cggggaggac gacttggggc agttcggggc gctcgcgaag ttccgcgtag ccggcggccg
     1621 tgttctggac ctgctcaggt gtgaggtgga cggtggtcgt gacggtctgc ctttcgcctg
     1681 cgtaccggtg ttccggggtg gagccccgtc gtgaggtcat gcggcagagc ttggccgcgc
     1741 ccggcttcag cccggcttca cctcggtgtc accccacgcg ccgcggcttc agctccggac
     1801 cgtcccgatc ctgctccggc tccagctccg gctccggctc cgggagaagg gtcccttgcg
     1861 agggctgtca ggctccgcga tcactcccac cgcgcggatt ccgggtcgac gccgtggact
     1921 gcggcgttcg cgaagacacg tcgcgcagcc agagggtgag gcccggcgcg agtgcgtcgt
     1981 aggcatcggc atacccggca tcaccgacgt acatccgccc catgcacgcc tgcatcgagt
     2041 gcgtgcagtc gaagtacccc gagatcaagg cacggtgccg ctccgcgagg gcgttcgctt
     2101 cgtcggaccc gggtgcgaca ccggcgtact tcgccgtggc gaggtcggcg ttcagggcgt
     2161 cgttcgctgc cgctaccgcc ttccagtcct gcggtgtcat cccggccgcc cgctcggcgt
     2221 actgcgtcca ctgcgcgctg tcgccccagc gggcctcggc ctgttcggcc caggcgggct
     2281 gccagtcggc gccgaagatg tcgacctgtt cctggggggt cagtctcatc ccgggtctcg
     2341 acgcctccat catgcgatcg accgcgccga ccatcttctg caggcgggcg atacgttcca
     2401 cgagctgtgc ccgctgccga cgcaggtggt cgcgcgcatc ggcgtccggg tcgtcgagga
     2461 cccggccgat ctcggcgagc ggagacccga gttcccggta gacaaggacg cggtggatac
     2521 gggcgatgtc gtcgcccgag tacacccggt acccggccca ggtacgctcg ctcggactca
     2581 cgagaccgat cgcgtcccag tggtgcagcg tcttcacact gaccccgacg agcgcagccg
     2641 tccggccgac ggtaagcccg tcgggaccgg gcggttcggc gccctccccg gtgaaggccg
     2701 gctcgtgctc gcgggcattg ctcgtcatcg gctcagtgtc gttcacctcg ccgatgccag
     2761 gacttccggg ccccgcactc ccgaagctgc cgcgacgtgg cgagcggttc ggcgtgatgc
     2821 tcccgtctcg catcccggtg cggtgccctt tcgtgttccg gtccgtccgc tgcgatgccc
     2881 gccgcgccca ggtcgttctc ctccgcctcg ccgcgcgatc cggccgagtg gctcacgcgc
     2941 cggtcgccac gcccgcgttc gtgaggatgt cgcgtgccgg cagcgcggtg ctccgggcgg
     3001 cggtcaggcc ggaggccgcc agatgggcgt ccacgatgcg gaggccgccc gcgtaaccgg
     3061 cgaagtcggg cagtccgacg ggctgctgcc ccaggtgccg cgcggtggcg tcgccgtaca
     3121 cgtacgcggg caggttctgc atcccggcca catcgatccc ggccgagagc ttctcgtgga
     3181 cgtcgtccag ttccgcaccg gacagcgccg tcgcccaggg ccccatggcc cgctcgcccg
     3241 ccagttcccg gacgaacgcc tcggccagtc cttcggccac gacctgctcg ccgaccgtga
     3301 ccgtcagcgg gttccagacg acattggcgt aacgcacgtt gtggtgcagc tcgtgtgcgg
     3361 cggcgtaacc gatcttcgcc aggctggtcg cggtgggcca catcgtcagt tggatcgccc
     3421 ccgggatacc gcccatgccg aagtagccgg cgttgcggac cgtcaggagg tcgtcatcgg
     3481 ggtctccgag caccaggacg acatgtacgg tctcggcgct cctgattccg ggcacctcac
     3541 cgctcagtcg ctcccacgct gcggcgaggc agttctcgat ctggttccac acccccgctt
     3601 cccgcatccg gctcagggct gccaggtagc gcgggtcctc gcgatcgatc cggaagccac
     3661 tgcccatctg atgcatcttg accatgtcca gatcacccac cgcggacatc gcgctctgga
     3721 gcggactgag cagttcccgc agggcgtcgg gccgttcctc caacggtcgt cgcagcagat
     3781 cgaacatggc ggacgccgtg tcatgaacaa caatcttcat ggcctgggac cgtagggcct
     3841 cctgttgcag gagggtcaag ccgtgccgcg gaaggaaacg ttgctcgatg cggcagatcg
     3901 gctgcgcggt ggcttcccct cgtacggggg acaccgcttt caccggccgc cgcccgggac
     3961 gccgctaccg ccgacgcccc gtccgatgag gcgctggtcg ccttcgccgc gtaccaggag
     4021 ttcgagaagg aactgatcga tgccggcgag ttcgtcagca gcgagggcct cagccatccg
     4081 gctgtcagca cccacggtac gtaggacgcc ggacggacgg cctccaccgg ccaccggccg
     4141 gcccgcgtcg gcctgaccca ccgagcgatc cggctgaccc tcatggtcca cgactgcctc
     4201 ccggacgacg ccggcgtgac cggcctgatc aacagcgtct ggacccgggg agaggtgggc
     4261 ccgtaccagg tgcaggcagc gatcgcagcc gtgcacgcga cggccgcgtc gccgaagcgg
     4321 acggacttgg ccccggatcg cggcactgta cctgtggcgc ggagcagcga taccttctcg
     4381 accgggccga ccgcctcagc tgacaagttc agtcacccgt tgctccgtcg gtccgctccc
     4441 gtaggaagtc ggcgtggccg ttgtggcggg cgtactcctg gatcatcaat acgtagaccc
     4501 agcgcaggct gagggagact ccgcgcgagg acacgaaggt ctcgtcgagg tcgtgcccgg
     4561 ccgctgccac gtcgcacgct tcgacctccg cccgcaacag cccgaagtcc ctctgcgcat
     4621 cagccgcgtg aactccgtcg agtccctcgt cgccgtccga cgggccggcg aagacatcgc
     4681 cgatggcctc acctgcgaaa cttcgcctga accaccatcg ctccatctcc gccatgtgcc
     4741 ggaccaggcc caggagggtg aggttcgacg gctccacggt cgtccgcgcc aactgggcct
     4801 gctgcagccc ggcgcacttg gccagcaacg tttcccggtg ccggcccagc cagccctcca
     4861 gcatccgacg ctcggtcacg gtacccaggt cacccagctg attgctgcgc tcgaccggtg
     4921 gcgctgtcca tgtcatggat ccaccctgca ccgccgtcca ggagggttca agcagacagg
     4981 atggcagcgt ggccgggcgg gatccggcgt tctccgatcg ctgcacggtc gcggacgcgg
     5041 acgtcggctg cgagcgctgc gacggcacgg aggtatagcc gtaggggccg ttgtcggctg
     5101 ccggtcccag gaccagggcg tggaccacca ccgggcggaa ggcggccacc gaaccggagt
     5161 tcgtcgccct taggatgcag ggggcctgcg agtgggtgat ctctcggtgc cgccgtggcc
     5221 atggccggag caggagtgtg tgcagtgagg acgtcgacga ggccccggag gcccgggttc
     5281 gcggaggcgg ccctggtgtc ggttctgctg gcgacggcgg ggtgcgccgg agggaccgga
     5341 accgacccgg gcggcgggat ggcaccgaag gccaggacct acctcacctc cgccctggac
     5401 gtgatggaga aacgctccct ggtcaccgcg gacgtggact ggccgaaggt acgccgggac
     5461 gccttcacgc gcgcggagag cgcgcggacg cctgccggga cgtacgcgtc gatccggcgg
     5521 gccctgcggg acctgggcga ccggcacagc accttcttcg atccggaaga agcctcccag
     5581 gccctcaaca caccgactga cgatctgatg ctccccgaag ggcgccggct gcccggcggc
     5641 atcggctatc tgatgctgcc cccggtccct tccgcccgtg tggccgcgcc gtacgtccgc
     5701 tcggcacgct ccaccgtggg tgggatggac gcccaaggcg cctgcggctg ggttgtcgat
     5761 ctgcggagca acagcggcgg ggacatgtgg gggccgctcg cctccgtggg gccgatactc
     5821 ggggacggca ccgttggcgc agccgtctac gcggacggca agaggtcccc gtggacgatc
     5881 gacaacggca ccccccgtca gcactcggac gactgggggc cggccgaatc cctcgcccga
     5941 ccggcgccgc cggtggctgt cctgacgagc cgcaggaccg cgagcgccgc agaggccgtg
     6001 accatcgcgt tccggggccg ccccgacacc cgtacgttcg gagaggcgac ggccggtgtc
     6061 cccaccgcga acgcgccgta ccgcctgtcc gacggcgcgt tggtcatcct gaccgtggca
     6121 cgcgaagccg accggaccgg ccacgtgtac gacgggccca tcacacccga tgtggaagtc
     6181 ccggaaacac gcggagacga ccaggccctc gaagccgcca cggactggct gaagacccga
     6241 aaggcatgcc ggaccccctg aaccacccaa cccacaagac cgttggccga gaagccccgg
     6301 ccggcgcctg ctgtcaaggc gcgctccgcg tggacgacgg cgggccggga tgaacgcggt
     6361 cggcggccac tgcccgtcgt ctgcgcacca tggccgggcg aggctccacc cacacgaagg
     6421 gcccacactc atgcgcactc tctacgtcgt cacccatccg gaagcgacgc accacgtcga
     6481 aaaggtcgtc ggtggatggc acgactcgcg gctgacgccc accggtgtcc gcgcggcggc
     6541 ctctatcgcc caagcgctac gggccgtcgt cccggacgac gccgaggtcg agctgtactc
     6601 ctcggatctg cggcgcaccc ggcagacggc cgaggaggtg gccgaactgt ttggcgtgca
     6661 accggtcctg gacccgaggc tgcgggagaa gtcctacgga gaagcggagg gcaagccgca
     6721 ggagtggctg gaccggcggt tcgtcccgcc gccggccgtc ggggagcgga tggatcacga
     6781 cgagggcgtg gcgggctccg agaccaaggc ggtatgggcc cagcggatct acgcggccat
     6841 ggacgagatc ctgcggagcc cgtgcgagca ccagatcatc gtgacgcacg gcggttccct
     6901 gacatgcgtt gtggcgtcct ggatcaggat gccacttgag tcggccggat acgccggctt
     6961 cagggcgccc tccgggagca tcaccaccct gcacgaagac gacttcttcc acaatcgaca
     7021 cgtcgtcagc ctcggtgaca cccgtcatct cgatcccgcc gaagccggct gacctcaacc
     7081 cggcccgcga cattctctcc tggaatccca tggccgccgc cctgctcatc gacttctccg
     7141 gaattcccga gaggaatcgc aattacgcgt ggatggtttt ctcggacccc gccatgaagg
     7201 tgattcacgc ggactggaaa aacaccgcgc actcctgcgt tgccatgctc aggacggaag
     7261 ccggtcgcaa ctcccaggac ccacgcatgg ccaccctcgt cggtgagctc tccctgcgtg
     7321 acgacggctt ccgccgccgg cgggggggcc gtcacatcgc caccaggaac aggggcagca
     7381 aagtgctgcg cgacccggta gcgggcgagt tggccctcga ccgggacgcc ctcgcctgcg
     7441 cgaacgaccc cgatcagcag ttggtggtct ggaccgccga gcccggcacc gcctcccatg
     7501 acgccctgcg catcctcgcc tcctggaccg cggacaccca gggggccgtc tcccggacaa
     7561 ccgactgaca accggcgcgc gaggcggtcg tcgtccgagc gcgatccggc ggaccgcggg
     7621 ggcaccccct cccgccggca gcccgcaccc gacggccgca ctcaacacgc cctgaaccgc
     7681 gttcggttca ggaggtctcg ccggtccggt gaggggccgc cctgttacgt cctcaccatg
     7741 tgcccatcga ggcgccatca tgcggggccg gaacagtgac gcgcatgaac acgagcatgc
     7801 gtgtgaacac caacccgaac ccccacccga gacgggggat actctccgcg ctcctggccc
     7861 tgtccgcctc ggccgccctg gccgttcccg gaacggcaac cgcccaggag cctgccggcg
     7921 ccaccgcccc tgccccgccg atcagttggg gcccctgccc caaggccgat ccgccctacc
     7981 ccgatcccag cccgaaggca cagtgtgcga cggtcaaggt tccgctcgac tggtcgaagc
     8041 cgacgggccc gaagatcggc atcttcgtcg cccgctaccg ggccaccggc cccgcgcggc
     8101 ggatcggtgt cctgatgtcg aacccgggcg gtcccggggc gcccggggcc gatgacgcgc
     8161 tgtacgcgga cgaccccgtc gggggctact ccccggccat gctccagcgc ttcgacatga
     8221 tcggcttcga cccccgcggc gtcggccgca gccagggcgc ccgttgcgac gagacgatca
     8281 acgacccggt cccggcccgc ccccgcgacg cggccgggtt cgcgcggttg cgcaccctga
     8341 acggccgact ggcggacagc tgcctcaagc ggacgggccc gctcgccgcc catatggacg
     8401 gcgagagcgt ggcccgcgac atggacgcga tccgcgccgc cctcggcgaa cgccggatca
     8461 gcttcctcgg ccactcctac ggcacgttcc tcggcgagcg ttacgcccgc ctgttcccgg
     8521 ggaacctgcg cgcactggcc ctcgacagcg cgatggaccc cgaccggccg gacgccgagc
     8581 gctacctcac cgacggcagc gtcactctca acagcacctt ggagaagctc gctgcctggt
     8641 gcgccgagga cgcggcctgc gcgctgaagg accaggagct gacggccgtc accgatcagc
     8701 tgttcgcccg cgccgacgcg ggcacgctcc ttgagccggg ccccaaggga ccgacgcgga
     8761 cgaaggtcga cgccgatcgg ctgtccgact tcctcaccgg cgaactccgg gtgtggaacc
     8821 cggaggggac ggcacggcag ctggccgccc tgcacaccgg aaagggcgag gtccgctgga
     8881 ccagcagcag caccgacccc gccgcacagt tggtgctgtg ccgggactac gacttccgga
     8941 tccgcgacta cgcccagtac cgggccatcc gccagcgggt cgcgaaggcc gccccgcacg
     9001 tccgttacaa cacccaggcc ctggacctgg tcctcggctg ccagggctgg accatgccgc
     9061 cgaagccccg tcccgcccgg gcggagggtg acctcccgcc cgtactcgtg gtcaacgcca
     9121 cccatgacct ggcgactccg ctgacaggtg cgcgccgtat gacgaacgcc ttcccgaagg
     9181 cgtccctgtt caccatggac ctggtgggcc actggctcta ccgcaggggc gccccggagg
     9241 aggcgatgcg ggtgatcgac acctacctga ccggcctcaa gggctgagcc gggaaaggcc
     9301 gggagcggag gcgcaccgga tacgccgtac gcctgcgctc ccgcccttcg ggaccgcttc
     9361 ccccgtgccc aggaacagca gcccggaccg gaaacaactc cgggcagatc acgaccgcac
     9421 gcatgagtcg gcctccgtcg cgggagttcc gtttccgcac ccaccggtca ccggcgtcgc
     9481 gcacccgtgc accagccttt tgcgggcagg cgcgtccaag tctccgtaca cgggggctat
     9541 ttcgccgcgc atcgtgcgac gggagggctc cgccccggaa agcggggcgg agccctgcgt
     9601 cggccgctgg gtcaggtcca gcgaccggcg acacccacgg ctcatttcta acacaataat
     9661 gttcgcttga acattgcaat gtgagctccc gatgggcccg tcctgggggg tacggccaaa
     9721 cggagcagcg cgcgggcccg tcgcaggaat gaaccggaga acgatgcttc cggcacggtg
     9781 tcctgatacc cgcaggccgg gccgaccgaa agcggctcgg tcgtacggac ggcagacccg
     9841 cgcactccgg ccgggcgtga ctcgatcagg tgatcttgcg gtgccgtgcc gagtggctgc
     9901 ttgcggagcc gtgtcccggc cgcccggtgc tcggttgtgc agggcggccg tgtctccgcg
     9961 cggccgcccg tgcccgtccg ccccgcaagg agaccacgtg gtgcccgtct cttctccgag
    10021 cctcatcggc tccgagccgt tcgccatccc ccgagtgcgg ctgcccttcg gcacgccagg
    10081 tgagcggccc gacagtgagg tgctgcgggc gcacgccatc cggtggggtg aggacttcgg
    10141 gctgatcggc ccacggggcg gggcacggct ggccgagacg tcgctgctgg ggctgggggt
    10201 ggcgctgacc gggacggcgc cccgggccgg agccaccgta ctgatggact ggttcctgtg
    10261 ggcggtggtc ctcgacgacc gcgtcgatga cggcccgtgg gccgaggacg gggccctcga
    10321 ccggttctcc gccgcggtgg acgcgatcac ccgcgggcag gagggccggg ccggcgttca
    10381 cgacccgatg ctgaccgtgc tcatcgacga cctctggccg cgcacgggcc gcctggccga
    10441 cgaggcgtgg ctggagcggc ttcgcgggca tctcctgcac catctcgacg cccagcgcga
    10501 tctggtgcgg atgcgggaga cggcggccga catcgggtcc gaggagtacg tacgcatccg
    10561 ccggcacaca ttcggtgcgc cgctgttctt cgacctgatc gaagccgccg acggcttggt
    10621 gctgccggcc gacccgtgcg ggcagggctg ctggccagta ctgcgggacc gggcggccga
    10681 tgtcgtgtcg tggacgaacg acatccactc cgtggcgaag gacgtcgtcc tcggtgaacg
    10741 gttcaacctg gtgacggtcc tcgcgcagga acggagcctg actccgcagg cggccgtgga
    10801 cgccgcgcac gagatgctgg cgacggcggt gagcgacttc accgccgtca agcggcgcca
    10861 cctcgggcac gcggacctcc cggaagccga ccgtccggac gtggcgcggg cggccggccg
    10921 gttggagcag gtgatgacgg ccagcgtgga ctggcaccgc accacgtccc gctaccacct
    10981 ccagtccggc atccccgcgc aggaccgtca cgggtccgta cgcacggggg aggcgacgcc
    11041 gacgctgaag tcccggcagt tcgagaccga cccgtatccc ctgtacgaac ggctgcgcac
    11101 cgcgttcccc ctcgcctatg acgagccgac cgacacctgg ctgctgagcc gccacgcgga
    11161 tgtccgcacc gctttgacgg accagcggtt caccaacgcc aactacacct ggcagatcac
    11221 cccgctcctg ggccacagca tcgtgtccat ggacggccgt gagcacaccg cccaccgggc
    11281 cctgctcacc ccggagttcc gcagccgggc cctggccgtc atgcacgact ccatcaccga
    11341 ggtcgccacc tcgctggtcg agcggctccg cggccgtgac accgccgacc tcatcaccga
    11401 attcaccact cccctgcccg tccaggtgat cgcccgcctc ctcggcctgc ccaccgacac
    11461 ccccgagcag gtcgcccggc tgcgcaactg gaccaaggtc ggtttctcct atctcggcaa
    11521 ctaccgccag gaccccggcc tcctcaccta cgggctggcc agccgtgacg atttctacgc
    11581 ctacctccag ccctacctgg acgcccgccg cactcagccg ggcaacgacc tcatctcggt
    11641 gatgttcgac tccgtcgtcg acgagcagcc gttgtccgag gagtacatcc gcggctgctg
    11701 cgccatcctg ctgaccgcgg gcagcgaaac cagcaacgcg gggctggcca acctcatcgt
    11761 caacgtcctc gacgagcccg gcgtccggga cgccgtccgc cgtgaccccg cactcgtcga
    11821 ccacgcgctc accgagaccc tgcgccggga cgcgcccatg caactggtgc tgcgccagac
    11881 gtccgaggcg gtggaactgc cttccgggac cgttccggcc ggagcgacgg tcgcctgtct
    11941 gatcggggcg gccaaccgcg acccggaacg cttccggctg cccgacgagt tcgacctcca
    12001 ccgcaccgac agcatcgacc gcgagtacag cgcggcctcc tcccacgtcg cgttcggcgc
    12061 cggccgccac ttctgcctcg gctcccatct ggtccgtgcc gaactgaccg ccggcctgcg
    12121 catcctgctc gacgccttcc ccgacctgcg gtgggcgccc ggattcaccc cccggccgac
    12181 cggcttcgtc aagcgctgcc ccccacgcct ggatgtgacc ctgtgaccac acgcgtcgag
    12241 ccggcctccg accggcccgc cctgccctcg ccctgcgggt acggcagcag ttacgtggcc
    12301 catcacaccc cgggcgaacg gtcgcgcctg ggaacgctcg aagcggcgtt cgaccccgcc
    12361 accatccagg ccctcgtcgg cctgtccctg cccgaggccg cggtctgcct ggaactggga
    12421 gcgggtgccg gatccatcgc ggcctggctg gccgctcatc gcccccgcgg tcacatcgtc
    12481 gccaccgaca ccgacatccg gttcctccgc ttccagcccg gtgcacctgt gcgggtcctc
    12541 cggcacgacg tcgtcaccga ggacttcccg gacgcctcct tcgacctcgt ccacgcccgc
    12601 gccctgctgt gccacttacc ggaccacgac cggattctcg aacgcgcggc acgctgggtc
    12661 cgccccggtg gctggctcgt cgtcgaggac ctcaccgtgc agcccgtcga tgcctcaccc
    12721 cacccgatcc tccgcaaggt cacccgggcg ggcgaagtcc tcttccgtac caccgtcggc
    12781 accgatctgc ggtgggccca gaccctccca cagcgactgc ggggcatcgg cctccatgac
    12841 gtccgggccc ggaccacgcc cggaacgatc ggtgacggcg gtgccaccga tgccttctgg
    12901 acggccacct tcgaacagtc ccttcccgcg cacctcgccg ccggcactct ccggcacgag
    12961 gacatcgagg ccatgcgcgc tctgcaccgc gctcccggct tcaccgacac cgccgtggcc
    13021 atggtgagcg cctggggcag gaagacatga cccctctccc cgtccaccgg gagaaggagc
    13081 ctgccgtggg cccggcgcca tccggccacg gctcgaatct gctcgacagg acctatctct
    13141 cgtacagcgg ccgcgaccag ccggtcatca ccttggccat ggactatcgc ggaactccgc
    13201 ccgccctgga tctgctcgtt gggcgcgtga aggagcgtgc ggcgtgcatc ccccgtctcc
    13261 gcgccggcac cgccgccctc ggaagcaacg tcctcggcgc cgccgtgagc gatatcgaca
    13321 aagagacggg ccgcatctcc cgcagcccgt tcgagctcgt cggcgggctg ccgctctggg
    13381 acgtccggct ccttgaggga aaacccggga gcgcgttctt ccgggtctgt ttcagggcac
    13441 accacggctt cctggacgga gtgggcgcga cccacgcggc gacggccctg ctgccggacg
    13501 agcccggcga gggcgcccgt ctgcatccgc cgacaagccc cggcgtccgt ggcatggctc
    13561 gggtcctcaa ggacatggcc tgctccctgg tgcaccggtc cgcatggtca cccccgcact
    13621 ccgccgctcc cggccacacg gacgggcgct ccgtctaccg ggacgtaccc gtcgcggtcc
    13681 tgcgcaccta cgccgacacc tacggcgtga gcgtcaacga tgtgagcctg gccgcgctcg
    13741 gcctggcgtt cggcgattgg cagcgcgacc gcgttcccgc ggaatcccgg cgcgacatcg
    13801 tggcaagcgt ggcgatgtcg accagaacac cgcaggaacg gcaccacgcc ggaaaccggc
    13861 tcggggtgta ccgcctgaaa ttcccccacc ggatcgaatc gttcgcggaa gccgtctccc
    13921 tcgtgtgccg gcagacggcg aaagtccggg acacccggca acgcgatgcc ctgcggacgg
    13981 cgctgggtgc cccggtcccg ccgaagctcg gtgtgcgggc cttcagttcc ctgctgaacc
    14041 cgcaggcgac cccactcgtg atcagcagcg tctcccttcc ggagaaccac accttgttcg
    14101 gcgccgatct gtgtgcggcc tcgatgacgc tgaacgtgtt cgcgaacttc ccggcctata
    14161 tctccttcac gcgaacccct gagaacgtcc gctgtgccgc ggtctccgac ccggcccgca
    14221 actccgtcct cgccgtaccg gagcactggg cgaactgcct cgcgtgatga cgcggggccg
    14281 ccgggtccgc ctcgtacgaa cgccgacggc acccggaagc ctgaaaaccg ccgctcgacc
    14341 cgtgcgaagc gtgcgctgat ccgcgttccc cgattactgg aacgtaggtt gggcgctgaa
    14401 cagttcatgc ctcacgcatc ggttgaaaga cggacggtac ccatgagtga ccacgcgatg
    14461 acgcccggac cggcggtgca tcagaagatc gacacgtcgg tgccgcactc ggccaggatc
    14521 tggaactact ggctgggcgg gaaggaccac taccccgtcg acgaggcggc cggcgacgcg
    14581 tacagcgccg tcttccccgg catcgtcacc atcgcccgca gcagtcgcgc ctttctgcgc
    14641 cgcaccatca cgtatctggt caatgaggcg ggcatcagac agttcctcga cgtcgggacc
    14701 ggcctgccga ccgagaacaa cacccatgag gtcgcccagc gtctcgctcc cgagagcagg
    14761 atcgtctacg tcgaccacga cccgatggtc ctcgcgcacg cccgcgccct gctcacctcc
    14821 acccccgagg gagcgaccgc gtacgtcgac gccgaactgt ccgaccccga ccgcatcctg
    14881 gcggccgccg cgaaaacgct ggacctcacc cgccccaccg ccctgatcct cagcaacatc
    14941 ctgggtcacg tcgccgacta cgaccaggca cgcaccaccg tcacccgcct gatgaacgga
    15001 ctgccgtccg gcagttacct ctccatcaac gacggttcac ggggcaccga cgccgactac
    15061 gagcaggccc aggacgccta caacgagacc ggcgccgtcc cgtacttcct gcgtcccgtc
    15121 gaccggatcg tggcgtactt cgacggactg gaactcctgg accccggggt cgtctcggtt
    15181 cccctctggc gcccggaacc cgcctccacc gccccgggac ccatcggcga gcacggcggc
    15241 ctcgcccgca agccctgaca ccccgaacgc ccagggtcca ggggaccgct gcgggacggg
    15301 cccccgccgg acgagggttc agggccgctc cccgaccgct cgcggaaccg gagacaccga
    15361 cccggcggac gtccgacggg acagccctca gcgacccctg gcgcacaggg ccgcgtccac
    15421 ggccccctgg aggcggcgca gattctcgcc ctcggccgcc caggtcgtgg tgtagaccgt
    15481 cacggtgccg cggtggcccg tggcccggcc gccgcccacc gagtcgccgg gcagatcgcc
    15541 gccatggccc cagtagacgc cgccgcagct gagcgggatc gaggcgacgc cgtagccgta
    15601 gcggctgccc gccgggtaga cgtcacggtt gccgacggcg gtggtgtcgt gcgtcatcag
    15661 gcgcagcgcc cagtcgggca ggagccggcc gccgaacagg ccgtcccaga aggtgttgag
    15721 gtcctcgggc gtcgagacga gcccgccgga tgcgccgaac tcgtacccgg gaagctcggt
    15781 cacatccacc cggccggcct ccggacgcgc cgggtggaca ccgtagttac gggcgtgcgg
    15841 cccgcgcagg gtcagctcgc cgggagcggg ccagtatgtg tcgtccaggt gcagcgggcg
    15901 cagaatcgtg cgctcgatgt acgtacggaa gccgacgccc gacgtcctgt cgatcaccat
    15961 gccgaggacc agatagttgg tgttggaata gccccagtcg gcgccgggct cgaagacggg
    16021 cttctccttg agcgcgaggg ccagatagtc ctccgccgtg ccgggccggg tccagtcgac
    16081 cagcgcggag tactccggca atccgctggt ctgcttgagc aactgacgta cggtgatgtc
    16141 gcgttcggag agctggggga cgtaggtgcc cgcgcggtcg tcgagtcgga tccgcccgtc
    16201 cgccaccagc ttcatcacgg cggccgcggt gaacgccttg gtgttgctgg ccagccggaa
    16261 tcggccctgc gcgtcggcca tcggacggcc cgagaccatg tccgaaaccc cggcggtacg
    16321 ggtcgccctg ccgtcgtacg cgagagctcc cggcaccccg ccccggtcga ccagcagatc
    16381 caactgcctc tgcaccgggt tcggttggtg tgccactgcc gccggggcga acgccccggt
    16441 gagcgttgcg gcgagcagga ctgcgacggc cggacgcttg cgctgcatga aactctcccc
    16501 ctggtcgtgg cccgccctgt gcgggccgat cgttcgctct ccgacgactc tgacaggctc
    16561 cccgcacagg atccttacgc ctggcccccc gaatcggggg tgtggccaca cccccttgac
    16621 atgacgcgga acgcctcgcc cgacgccgcc gggctcggga ccaccgggcg cacgggccgt
    16681 gcgtatccgc tcgatcgcgg gtggcgccga caggggctgg tgtcaccgct tcccggagga
    16741 cagccaggtg agggctgctg tggtcatcgc ttcgacgccg gtgctcagcg tgggttcgac
    16801 gaccggggcg aagtgcgggg agtggttgga cggaatgtcc cggtccgtcg ttccggcggc
    16861 ggccgctttc cggtaggagt cgggagcggt gccgccgaag aaccagtagc agaccggggc
    16921 gcccgacgcg gtgccgaaga tcccgcagtc ctcgctgccg gtcacgggtc ccgggtcgaa
    16981 gacccgctgt gcgccgaagt ggccgcggaa ggccgtgacg gtgcgccgga cggccgcctc
    17041 gtcgttcacg agaacgggga aggcggcgat cgggtcgatg tcgggcgagc gggtggcacc
    17101 ggatgcctcg gcctcggccc gcacgatccg tttcaccgct gccagcactc gggcccgtac
    17161 ctcatcggtg taggtgcgga tgttgagtct gagctcggcg gtgtccggga tgatgttgtc
    17221 cttcgtaccg gcgttgagcg cgccgacggt gacgacggcg gtgtcgccgc cggcgatctc
    17281 gcgtgagacg acggtctgca ggcgcatcac ggtggaggcg gccatgacga cggggtcgat
    17341 ggcggcctcg gggcgtgacc cgtgcgcgcc cttcccgtac atcgtgacag cgagcgcgtc
    17401 ggcggcggcg agcgcggggc cggggtggca gccgaccgta ccggccggaa acggtccgac
    17461 gtgctggccc aggacgacat ccggtgtacc gaaccggtcg aagaggccgt cgtcgaccat
    17521 ggcgctggct ccttggccga tctcctcggc gggctggaac acggccgtga tggttccgga
    17581 ccagtgggcc cgtccgtcgg ccagcaggtc gagtgtgccc aggaggcagg tgacgtgcat
    17641 gtcgtgacca caggcgtgca tgacgccgtc cgccgtgctg gcgtagggca ggccggtctg
    17701 ttcggtgacg ggcagtgcgt cgaagtcggc gcgcagcagg acatgggggc cgtcgccgtt
    17761 cgcgagcaca ccgaccacgc cggtgcgtcc gatgccggtg gtgacccgca gaccgagctt
    17821 ccgcagccgc tcggcgacga tgccggccgt gcgtgtctcg gcgaaggaca gttccggatg
    17881 cttgtgcagg tcccggtaga ggtccgcgag tccgtcccgc acatccggca atcgcgtcag
    17941 caggggagaa cctgccgtcg tgtcaggggc gctgtcagcg gcgctgtcgg tgtcactcat
    18001 gtgttcatgg tcgggggacc ctgcgggccc ggcctgtggg ccgggccatt cgtgggccgg
    18061 gcatcaggag agcggcgacg cagaatcccg cgaaggaagg cgtaccggac tcacggcaag
    18121 gagctggacg ccgacggtgg gcgggcgggg cgcttgccgc gcggggaagt cccactggtc
    18181 gggggcgatc cacaccgcac cggtcagcgc ggcgatggcg acgaaccact cgccgcggaa
    18241 ctgtttgggc gggacgccac acgagacgtc gatgaggaag cgtcccgcgg tggggcccac
    18301 gacggcgagc gcgagactgc ccagaaccgg caggccgacc tccaccccgg tctgcgcgcc
    18361 gacgatggcg taccagggca gagcaaagga ggtgacgaac tggaagagcc cttcccggag
    18421 gagctgcccc ctgtcgtagg ccaggtggtg gccgatgatc ccggcgatga ggcacagcac
    18481 gaggtacgag gaattggtga gcgcggccgg gacatgaccc accaggacgt cgcggctgat
    18541 accccgccga tgccgccgag cagggccatc agcaggatgc cgaccacggt gaagttcttg
    18601 tagtggtcgg gacggcgggc gagcagcgcg ccgttgaggg cgttggtggt cgccgcggcc
    18661 aggttgatga acgtgccgcc tccggtgaac tcgaaggatc cgaagccaac ggccatggcc
    18721 ggctctctcg tgctcacggg gttccttccg tggagggccg accgcggcca ccgccgatca
    18781 gcgcgttcca cgccgcgccg cccgtacgga cgcgccgcgg cgcggcgcgg gtgtgctccg
    18841 tcccctcggg tgcgcctgcc ccggccgtgg cgaggggcag ccgcgtcgtg cgcgtggtgg
    18901 tcagggcgtg acgatggcga agtcggggtc gggggtgtcg agcaggctcg cgagagtggc
    18961 gaagacctgt gggtcgccct ggaccttcac atcgtccaag cccgcacccg cgaggacgcc
    19021 gagcaggtgc cgcttcgtca aggtcagcgt cagatcggcg gccggcgccg aaccgtgcgc
    19081 gtcgggggcg ccgtcggtgc tgcggtacgt cagcgccccg ttcgacagca gcaggtgcca
    19141 ggtgcggctc tcgtcggtga cgtgccaggc catcgcgagc ttcttggtcc aggcgcgcgg
    19201 cccgtcgatg cggatggcga gcgagtcgat gagcatgtcg acggtcagtg ccatcgccat
    19261 ctcggggttg gtcgtctcca aggaggtgtg cgcgaccgag ccacgcagtt cctgggcacc
    19321 catcaggtag aagttgcgcc aggtgccgtt ctccgagccg tgaccgagct tctcgtacac
    19381 cgaagccagt gcctccttgg ccgccgtgtc gcggggggcg gcgaagaccg cgtggccgag
    19441 cagcgtggcg gcgaagcgca ggtctcccga tgccgcgtac tcctcaccct tggcgaccag
    19501 ggcggcgacg ccgccgtagt cggcggcgaa ccgggtggcc tgctcggtcg gcgggtgctc
    19561 ccacaggtgc gcggggttgc cgtcgaacca gcccatgtaa cgctggtaga tggccttgac
    19621 gttgtggctg agcgaaccgt agtagccacg gttcgcccac cggcccgcga gggcgggcgg
    19681 cagttcgatc cgctcggcga tctcgctccc ggtcagtcct tgattggtca tgcgcagggt
    19741 ctggtcgtgc atataggccc acatgtcgcg ctgcccggcc aggtggtcga cgatgcggtc
    19801 cttgccccag gtcggccagt ggtgggaggc gaacgcgacc tcggcccggt cgccgtacag
    19861 tgcgatggtc tcgttcaggt agtgggccca gatacgggtg tcgcggacca ccgcgccgcg
    19921 cagggtcagg atgttgtgca tgttgtgtgt cgcgttctcc gccatgcaca gcgcgcgccg
    19981 gtcggggaag tagaagttca tctccgacgg tgcttcggtg cccggcgtca tctggaagat
    20041 gatccgtacc ccgtcgacgg tctcctcctg gccggtacgg gtgatgtcga gcgtcggcgg
    20101 gatgagggtg atggtgcccg tggaggtcgt catgcccagg cccgcgctga tctgaccggc
    20161 ggggcccttg tccagttcgg cgccgtacat gtacaccgcg cggcgggtca tcgcgccgcc
    20221 cgcgtacacg ttctccgcga cggcgtgctc caggaacccg gccggggcga tcaccggcac
    20281 cggggcgtgg ccgtgcggca ggacgccgag cgagccgccg aagtggtcgc cgtgcgagtg
    20341 cgtgtagatc agcccggtga cctggcggtc gccccggtgc tcgcggtaca gcgcgagcgc
    20401 cgccaccgcg gtctcggcgg agatcagcgg gtcgatgacg atgacgccgg tatcaccctc
    20461 gacgagcgtc atgttcgaca ggtcgaggtt ccggacctgg tagatcccct cggtcacctc
    20521 gaacaagccc tgtttgttgc acagccggct ctggcgccac aggctcgggt gcgccgtgtc
    20581 cgggcactcc tcgtccagga acgcgtacgc gtcgccgtcc cagatcatcc ggccgtcgtc
    20641 cgtccggacg accgccggtg ccagggcggc gacgaatccc cgctcggcgt cttcgaagtc
    20701 ggacctgtct gcgtagtcga gatcagtcat atgtaacaag taacccatat gccatcaaat
    20761 tacccacttt cccttggcgc gtctcgccgt gcggcactcc cccggacccc ggcggccacc
    20821 tacccctgcg ggccgaggtg acctcgtacc acctgcacag gcggcgaccc gaccgccgga
    20881 gccgcgccgt ccgtacgtca ccgttgatcc ggttgtgccc cgtgcagcac actcggtgtt
    20941 tggcgccgcc cacgggaggg cggcggccgg acaacgggac cgctgtcccg taccactgga
    21001 ggtaccagaa atgacacctc ggaacaccga gttcgagctc gggggaatca accatctggc
    21061 gttggtctgt gcggatatgc gcagaaccgt ggacttctac tcgggccttc tcggtatgcc
    21121 gctcatcaag acgatcgagc ttcccggggg aagcggccag cacttcttct tcgactgtgg
    21181 gggtggtgac tgcgtggcct tcttctggtt cgcggacgcc cccgacggtg tgccaggaat
    21241 ctccgccccc gtatccctcc ccggccaggg ggagttcctc agtgccgtcg gttcgatgaa
    21301 ccatgtcgcc ttccatgtgc cgccggagcg gttcgacgag taccgcgccc gcctggttgc
    21361 caagggggtg gaggtcagcc cggtcatgaa ccacgacgac agtccgacga ccgtggccgc
    21421 ccgtctgcag gaaggggtgt acgtacggtc cttctacttc caggaccccg acgggatcct
    21481 gttggaattc gcctgctgga tcaagcagcc gaccggtgag ccgcacaaca ccaccgacga
    21541 gcccaggaca gcggccgacc gcactccgcg caccccggtc ccggcctcgg tcccggcctg
    21601 acgattcgta cggcacgcac cgctccctca cgacgccgcg acgcggggag cggtgcggtg
    21661 gggagctgtg cggtgcgggc acccgccgct ccgtgacggc cggggcccct tacccttgcc
    21721 tggttcgagg atgcgcgggc gaggagaggc ggacaccggg gtggcgcggg taacggctgt
    21781 gagcagacac gggacatact ccttcagcaa gccgaaccgt acgagcatca tgttgctcgc
    21841 cggtctcggc gtcgagggtg atgtccacgc ggggaagacc atcaagcacc agttccgtat
    21901 gacctacgag ccggatctgc ccaacctgcg ccaggtgcac ctcatgcacg aggaactctt
    21961 cgacgaactc gccacgaagg gcttcgccgt ctccgcggga caactcggcg agaacatctc
    22021 cacgcgcggt atcgacctgc tcggcctgcc caccggctcc ctgctccacc tcggcggcga
    22081 agcgatcgta gaagtgacag gtctgcgcaa cccgtgttca aagatcgacg cgttccagaa
    22141 gggccttctc agggaagtct tcgaactcga cgagacgacg gacggcttcg ctttcaagtc
    22201 cgggatcatg ggcgtggtcc ggcaag
//
