LOCUS       NZ_LWLE01000030        19568 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0281 scaffold36, whole genome shotgun sequence.
ACCESSION   NZ_LWLE01000030
VERSION     NZ_LWLE01000030.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0281
  ORGANISM  Streptomyces sp. TSRI0281
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 19568)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19568)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905125.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,600
            CDSs (total)                      :: 8,518
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 82
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 345
            CDSs (without protein)            :: 343
            Pseudo Genes (ambiguous residues) :: 0 of 345
            Pseudo Genes (frameshifted)       :: 151 of 345
            Pseudo Genes (incomplete)         :: 273 of 345
            Pseudo Genes (internal stop)      :: 33 of 345
            Pseudo Genes (multiple problems)  :: 102 of 345
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:13:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 19568
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWLE01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..19568
                     /collection_date="2014"
                     /country="USA"
                     /db_xref="taxon:1718998"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. TSRI0281"
                     /strain="TSRI0281"
                     /submitter_seqid="scaffold36"
     region          1..19568
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..19568
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..19568
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11866:>19568](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11867..>19568
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    50..66
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    184..200
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.57"
                     /tool="antismash"
     misc_feature    complement(220..235)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            252..1550
                     /locus_tag="A6A29_RS29045"
                     /old_locus_tag="A6A29_41430"
     CDS             252..1550
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157752.1"
                     /locus_tag="A6A29_RS29045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41430"
                     /product="aldolase/citrate lyase family protein"
                     /protein_id="WP_073724427.1"
                     /transl_table=11
                     /translation="MGQQEKVATSLAGTVGEHISASLAAVDAELARRYPGDPGTRQPVH
                     TVYVPGDVFAADTIRSWGDRALEALDAHAPDAASFAAALGIPEELAGPVHDRVRAKLER
                     EPVEDLRIDFEDGYGPRSDDEEDEAAARAALLVSQAYGDGTSAPYMGIRMKCMEAAVRD
                     RGIRTTDVFLTGLMRAGGLPDGLVLTLPKVTYPEQVTAFVQLLEAFEKAHGLDAGRIGF
                     EIQIETSQSILAADGTAAVARMIDAARGRATGLHYGTFDYSACVGVSPAYQAGDHPAAD
                     HAKAVMQVAAAGTGVRVCDGSTNVLPVGPTSQVHEAWRLHYGLTRRALARAYYQGWDMH
                     PGHLPTRYAAVYTFYREGLEQAAGRLAAYVAKAGGDVMDEPATAKALSGYLLRGIDCGA
                     LDTAEVARLTGLTRADLDAFASPRRGGLTVTAP"
     gene            complement(1641..2669)
                     /locus_tag="A6A29_RS29050"
                     /old_locus_tag="A6A29_41435"
     CDS             complement(1641..2669)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606976.1"
                     /locus_tag="A6A29_RS29050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41435"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_073724429.1"
                     /transl_table=11
                     /translation="MAETTRHSETRYGNRPTMKDVAARAGVGLKTVSRVVNSEPGVTPD
                     TERRVQEAIDALGFRRNDSARVLRKGRTASIGLVLEDLADPFYGPLSRAVEEVARAHGA
                     LLINGSSAEDPEREQELVLALCARRVDGLIVIPAGDDHRYLEPEIKAGIATVFVDRPAG
                     RIDADMVLSDSFGGAREGVAHLIAHGHRRIGFIGDQPRIHTATERLRGYHAAMTDAGIE
                     VQDAWVSLGSTDPDRVRDAAESMLRGPEPVTALFAGNNRVTVTVVRVLADRERPVALVG
                     FDDIELADLLGITVISQDAAAVGRTAAEHLFRRLDGVDHAPVRVELPTTLIARGSGERP
                     PA"
     misc_feature    2774..2788
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(2776..2787)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     misc_feature    complement(2781..2795)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.78"
                     /tool="antismash"
     gene            2865..3812
                     /locus_tag="A6A29_RS29055"
                     /old_locus_tag="A6A29_41440"
     CDS             2865..3812
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982914.1"
                     /locus_tag="A6A29_RS29055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41440"
                     /product="ROK family protein"
                     /protein_id="WP_073724431.1"
                     /transl_table=11
                     /translation="MHTDLVAALDIGGTKIAGALVDGGGTLLARAQRPTPALRDAETVM
                     AAVGDVLNELMESPLWGGAGSVGIGSAGPVDASAGTVSPVNVPAWRDFPLVERVRKATG
                     GLPVALVGDGVAMTAAEHWLGAARGYDNALCLVVSTGVGGGLVLGGRLHPGPTGNAGHI
                     GHLCVELDGDPCPCGSRGCVERIASGPNIARRALDGGWLPGPDGDATAAAVAAAARAGD
                     PVAVASYERAAQALAAGIAATATLVEIDIAVIGGGVAGAGEVLFAPLRRSLRDYATLSF
                     VRRLTVAPAVMGTDAGLVGAAAAAATAVRRPQAL"
     gene            4748..5656
                     /locus_tag="A6A29_RS29060"
                     /old_locus_tag="A6A29_41445"
     CDS             4748..5656
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718171.1"
                     /locus_tag="A6A29_RS29060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41445"
                     /product="virginiamycin B lyase"
                     /protein_id="WP_073724443.1"
                     /transl_table=11
                     /translation="MSSTERHRVVPVPGRGPYGVAVADDGALWVTLAGSGDIARVHRDG
                     PARVHAGGGGAGARPTSVARGSDGAMWFTQFLADAVGCVRPDGTVVSVPLPTRGAGPYG
                     ITAGPDGAMWFTEMNADRVGRVDDEGRVEEFVLPVEGGYPSGITAGADGALWFALNQAD
                     AIGRLDTAGRTTVHPLPTSGAAPVNIAAGEDGALWFTEIGAGRIGRLTYDGRIEEFRVS
                     APDARPHGIAAADGGGCWFTEWGSHRVGRMRPDGRVRTWALPEEVTEPHGIAVAGDGVV
                     WAAMESGELVGVTPPGEQGWG"
     misc_feature    5896..5911
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.54"
                     /tool="antismash"
     gene            5910..>6186
                     /locus_tag="A6A29_RS45490"
                     /pseudo=""
     CDS             5910..>6186
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000043: Heterocyclization (81% identity)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A29_RS45490"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /product="cytochrome P450"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHKREEPGDDLLSALVASAQDSEDLTEHDVRSLSLILLLAGYEPA
                     SNQLGSSILTLPRFPDRLKQLRENPGLLPTAVEELMRYAPAGDCALF"
     assembly_gap    6187..6201
                     /estimated_length=15
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6202..6532
                     /locus_tag="A6A29_RS45495"
     CDS             <6204..6532
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000043: Heterocyclization (83% identity)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="A6A29_RS45495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_158074485.1"
                     /sec_met_domain="p450 (E-value: 2.1e-11, bitscore: 32.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TLDEITLGDTVIPPYSAVLASTQAANRDPRRFEDPTGLRLDRPEN
                     HHTALGHGIHFCLGAALAHVALQVAIGSLLRRFPGLALATDERELRWSSPGSMLSGFSE
                     IPVTW"
     gene            complement(6644..8278)
                     /locus_tag="A6A29_RS29070"
                     /old_locus_tag="A6A29_41455"
     CDS             complement(6644..8278)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983946.1"
                     /locus_tag="A6A29_RS29070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41455"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_073724434.1"
                     /transl_table=11
                     /translation="MSTQLTLTNVSKGYVDHPVLEGVSLSIKPGDVVGIVGENGAGKTT
                     LLRLMAGVDQPDEGEVTVDSSGGIGLLGQTLDLPPHCTVRDAIDWALSDLRTMERDLHA
                     AEARMADATQAELDDYGNLMTRFEARGGYEADARAEAALDELGVGHIPFDRPLSALSGG
                     EQSRLALACTLATEPGLLLLDEPSNHLDDKAMAWLEDRLRAFPGTVVAVSHDRVFLERV
                     TDTILEVQGERHTVNRFGNGYSGFLAEKAAARRHWEEEYRTWLDDMQFQRVRSVTTAHR
                     VGYANRFHSNKLQYFNHGLRAERQVGSRVRNSLERLRRLEENPVPRPPDPLRFTAGLTD
                     TGRTFEHPLVTLSDVTVDHRLRVDGLTIDKRRRLLIHGPNGAGKTTLLNLLAGVQEPDS
                     GQVTRQGRISYLPQEVSVSRPRQTLLEAFAEGRVGTREEHEEQLASLGLFSPDSFRVAV
                     GGLSIGQQRRLTLARLVTEPADLLLLDEPTNHLALTLIEELEEALALFEGAVVIVSHDR
                     RLRARFTGEPMEVRDGVLRTAVGADAA"
     misc_feature    8572..8585
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.66"
                     /tool="antismash"
     gene            complement(8888..>9680)
                     /locus_tag="A6A29_RS29075"
                     /old_locus_tag="A6A29_41460"
                     /pseudo=""
     CDS             complement(8888..>9680)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137073.1"
                     /locus_tag="A6A29_RS29075"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="A6A29_41460"
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="GTAVDMAMYGLRPVVEMQFDAFAHPAFEQLVGHVAKMRNRTAGRL
                     PLPLVVRIPYGGGIGGVEHHSDSSDAYYVHTPACTSSLRGPWRTRTVCCAPPSSRTTPW
                     WCWSPSASTGRRSPGTSTRRPPWSRWGMPSCAVLAAPPSSSRTAPSLPVCLEAAEAARA
                     HGWDLAVLGLRTLVPSTTRASAIWCARAAGPSWCTSRAASPGSGRRSRPGHRALLLSPG
                     GPGAAGHGP"
     gene            complement(9777..10655)
                     /locus_tag="A6A29_RS29080"
                     /old_locus_tag="A6A29_41465"
     CDS             complement(9777..10655)
                     /GO_function="GO:0016624 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, disulfide as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975103.1"
                     /locus_tag="A6A29_RS29080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41465"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_079183075.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.1e-08,
                     bitscore: 24.2, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAARRGRPAARPGPLLPDRSPVRIIGTPRAAAVRPALARSLHRRL
                     VVGRGFNEQASTSARQGRLAVYPSSTGQEACQVAAASALRSTDWLFPTYRGTLAVHLRG
                     TPADETLALLHGAVHSGYDPWRWRTAPLCTPLATHLPHAVGLAHAARLRGDDMVALSLA
                     GDGATSEGDFHEALTFAGVLRAPVVFLVQNNGCAISVPLARHEATANAAGEAADRTAAE
                     LRAAFTVPQHAAPEALFAHIYARPTPQLRAQVAALHARESAADRWDGAAHGCSAGAAGA
                     DVHAPEGGVST"
     gene            complement(10742..11629)
                     /locus_tag="A6A29_RS29085"
                     /old_locus_tag="A6A29_41470"
     CDS             complement(10742..11629)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020629937.1"
                     /locus_tag="A6A29_RS29085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41470"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_073724436.1"
                     /sec_met_domain="PhyH (E-value: 2.1e-37, bitscore: 119.1,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSAQINTYRSDGFLTLDSGIEPDDLDRIREEVQRLEGIEHPGR
                     ILEKDGSTVRGIHGCHQVSDLFSRLVRLPSMLSVARRLVEDDVYVHQVKVNAKRALDGD
                     VWPWHQDYVFWEQKDGMQQPKAINAALFLDDVTEFNGPLLLIPGSHMENVPKNLPESDS
                     PADPNAFSDDPSNAFRGTAGTSGTAHSTVDSEKPEWASNLSADLDFRLRGDHLRPLVEK
                     HGIRSATGRAGDLLFFDPRIVHGSGTNMSPGDRTVALITYNSVANQLAEVAAPRPEFLA
                     ARDYRPLSPLSGRL"
     misc_feature    complement(11771..11780)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            11867..16681
                     /locus_tag="A6A29_RS29090"
                     /old_locus_tag="A6A29_41475"
     CDS             11867..16681
                     /NRPS_PKS="Domain: Cglyc (9-224). E-value: 8e-78. Score:
                     253.6. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29090_Cglyc.1"
                     /NRPS_PKS="Domain: AMP-binding (512-921). E-value: 9.1e-97.
                     Score: 316.1. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29090_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1028-1093). E-value: 1.3e-20.
                     Score: 65.4. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29090_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1109-1421). E-value:
                     2.4e-126. Score: 414.3. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29090_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1434-1591). E-value: 9.9e-40.
                     Score: 127.8. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29090_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="A6A29_RS29090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41475"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_073724439.1"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-104, bitscore:
                     337.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-13, bitscore:
                     40.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.2e-41, bitscore:
                     132.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTGTGAGLTDVLPLSPLQDGLLFHALYDEADADVYVVQFVLTL
                     SGPLDAARLRAATEGLLRRHPNLRAGFWQDGMKRAVQIIPRESVLPWTEHDLTGTAPDV
                     REDAFQRLLDTDRGRRFDPAHPPLMRAALVALGPEEHRLLISHHHLLVDGWSMPLLLAD
                     LFTLYENGGDERAMTPPPSFRDHLAWLASRDAEADRRAWREELAGLDHPTTVTAAPGTA
                     VPAPRTATTDAVGPREDAAAGAPTGPDVTGAPDAPADGRPRGARHQDPVHQQFVELDEP
                     TTAALTAQGRRHGLTLNTLVQGAWGLLLGALTGRDDVTFGAVVSGRSPEVDRSEKMVGL
                     FINTVPVRVRTRAGDTLATTLGTLQEHQARLAEHQFTGLSAIQRACGIPELFDTLLVFE
                     NYPLDPDALDLHADGLRLSDLEIRDRTHYPLSLVVIPGETLRLRVEHRADRCAPEVARD
                     LGPRLLRLLRAMADGLEEPAARLDLLSHQERAALLDTPREPAHALSGRTLPGLLDQQAA
                     LTPDALAVVCADERLTYREVASRSNRLARLLISRGAGPETLVALALPRGTEQVVAFLAV
                     LKAGAAYTPVDTSYPQERVCFLLADAAPVAVVTTAAEAHLLPPGAEPVVLDAPAFAAEL
                     AACSDADLTDAERLHPLHADHPVYALYTSGSTGRPKGVLMHAEPLLNLMAWYARTVPGE
                     PGAVASQFSTTAFDPAPLEMLSALTQGQTLTVATDLARHDPQELLDWLEREGARHLYTT
                     NTVVEALADAAAATGRTLPDLREVVQAGEALMPSQYVKRLFRDHPGRRLHNLYGPTETH
                     VVTAAVLGPDPDAWPHSAPIGTALPHTRVYVLDTWLRPVPPGVAGELYVGGVMPARGYV
                     RRAGLTASRFVAAPFGPPGGRLYRTGDLVRQRQGGALDFLGRADDQVKIGGQRVEPGET
                     RAALEALPDVAQAHVTVREDTPGVRRLVAYLVAAPGTHPVPADLRAALARTLPAPQVPA
                     DCVLLDALPRNANGKVDRSALPAPVVAGDAAGRAPRTDAERLLARLFQEVVGATAVGVD
                     DSFFALGGDSIMSMQLAGRARKEGLFFSPRDVFEQRTVALLAAVATPADDRAAGPARTE
                     GSGPFPATPIMHWFRELGGPVDGFSQSVVLQTPAALDERRLADLLQSVVDHHDVLRLRM
                     ETRPDGSWSPEVRPVGSVRAVDLIRRVDTGGLGSERTAALLEREAAAADRQLRPARGDI
                     LRAVWCDAGDAPGRLLLTAHHFAVDGVSWRILLADLVTAWQAVLAGRAPALEPVAVPFR
                     QWAQHLTDLAHDPAQTAQLPLWQRIASTASPLPSRVSPDPRRDLAGTVRRHTRELPVDP
                     TRALLTGVPAAFHAGMNDVLLTALTAAVVEWRRRRGTYATDLLLDLEGHGRDEGAGTLD
                     LSRTVGWFTTLHPVRLDLGRTDHRELGAGGPALGRAVKRVKEQLNAVPQHGLGHGLLRH
                     LNEDTAKELSTTAVPELCFNYLGRFTAPDDTDWSPAPEIHLLGGSVDSGLPFGRSLQLN
                     AYTRDTPDGPRLTALWSWPGALWDDADIAELADSWFTMLRALVRHTATGGAGGHSPSDL
                     PLVDLSQNDIDLLESELGEEDEESK"
     aSDomain        11894..12538
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29090_Cglyc.1"
                     /domain_subtypes="Cglyc"
                     /evalue="8.00E-78"
                     /label="A6A29_RS29090_Cglyc.1"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="224"
                     /protein_start="9"
                     /score="253.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLVDG"
                     /tool="antismash"
                     /translation="LTDVLPLSPLQDGLLFHALYDEADADVYVVQFVLTLSGPLDAARL
                     RAATEGLLRRHPNLRAGFWQDGMKRAVQIIPRESVLPWTEHDLTGTAPDVREDAFQRLL
                     DTDRGRRFDPAHPPLMRAALVALGPEEHRLLISHHHLLVDGWSMPLLLADLFTLYENGG
                     DERAMTPPPSFRDHLAWLASRDAEADRRAWREELAGLDHPTTVTAAPGTAVP"
     aSModule        11894..16639
                     /complete
                     /domains="nrpspksdomains_A6A29_RS29090_Cglyc.1"
                     /domains="nrpspksdomains_A6A29_RS29090_AMP-binding.1"
                     /domains="nrpspksdomains_A6A29_RS29090_PCP.1"
                     /domains="nrpspksdomains_A6A29_RS29090_Epimerization.1"
                     /domains="nrpspksdomains_A6A29_RS29090_TIGR01720.1"
                     /locus_tags="A6A29_RS29090"
                     /monomer_pairings="X -> D-X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11909..11947
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0001"
                     /evalue="7.50E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="27"
                     /protein_start="14"
                     /score="11.9"
                     /tool="antismash"
                     /translation="PLSPLQDGLLFHA"
     CDS_motif       11969..12082
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0002"
                     /evalue="1.80E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="72"
                     /protein_start="34"
                     /score="49.2"
                     /tool="antismash"
                     /translation="DVYVVQFVLTLSGPLDAARLRAATEGLLRRHPNLRAGF"
     CDS_motif       12305..12370
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0003"
                     /evalue="1.70E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="168"
                     /protein_start="146"
                     /score="33.3"
                     /tool="antismash"
                     /translation="HHHLLVDGWSMPLLLADLFTLY"
     CDS_motif       12815..12910
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0004"
                     /evalue="1.30E-17"
                     /label="C5_DCL_263-294"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="348"
                     /protein_start="316"
                     /score="56.2"
                     /tool="antismash"
                     /translation="DVTFGAVVSGRSPEVDRSEKMVGLFINTVPVR"
     CDS_motif       12959..13072
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0005"
                     /evalue="8.20E-17"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="402"
                     /protein_start="364"
                     /score="53.6"
                     /tool="antismash"
                     /translation="QEHQARLAEHQFTGLSAIQRACGIPELFDTLLVFENYP"
     aSDomain        13403..14629
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29090_AMP-binding.1"
                     /evalue="9.10E-97"
                     /label="A6A29_RS29090_AMP-binding.1"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="921"
                     /protein_start="512"
                     /score="316.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DQQAALTPDALAVVCADERLTYREVASRSNRLARLLISRGAGPET
                     LVALALPRGTEQVVAFLAVLKAGAAYTPVDTSYPQERVCFLLADAAPVAVVTTAAEAHL
                     LPPGAEPVVLDAPAFAAELAACSDADLTDAERLHPLHADHPVYALYTSGSTGRPKGVLM
                     HAEPLLNLMAWYARTVPGEPGAVASQFSTTAFDPAPLEMLSALTQGQTLTVATDLARHD
                     PQELLDWLEREGARHLYTTNTVVEALADAAAATGRTLPDLREVVQAGEALMPSQYVKRL
                     FRDHPGRRLHNLYGPTETHVVTAAVLGPDPDAWPHSAPIGTALPHTRVYVLDTWLRPVP
                     PGVAGELYVGGVMPARGYVRRAGLTASRFVAAPFGPPGGRLYRTGDLVRQRQGGALDFL
                     GRADDQVKIG"
     CDS_motif       13586..13627
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0006"
                     /evalue="5.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="587"
                     /protein_start="573"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LAVLKAGAAYTPVD"
     CDS_motif       13841..13891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0007"
                     /evalue="2.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="675"
                     /protein_start="658"
                     /score="23.4"
                     /tool="antismash"
                     /translation="YALYTSGSTGRPKGVLM"
     CDS_motif       14420..14509
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0008"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="881"
                     /protein_start="851"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PPGVAGELYVGGVMPARGYVRRAGLTASRF"
     CDS_motif       14594..14653
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0009"
                     /evalue="4.20E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="929"
                     /protein_start="909"
                     /score="31.7"
                     /tool="antismash"
                     /translation="FLGRADDQVKIGGQRVEPGE"
     aSDomain        14951..15145
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29090_PCP.1"
                     /evalue="1.30E-20"
                     /label="A6A29_RS29090_PCP.1"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="1093"
                     /protein_start="1028"
                     /score="65.4"
                     /tool="antismash"
                     /translation="ERLLARLFQEVVGATAVGVDDSFFALGGDSIMSMQLAGRARKEGL
                     FFSPRDVFEQRTVALLAAVA"
     aSDomain        15194..16129
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29090_Epimerization.1"
                     /evalue="2.40E-126"
                     /label="A6A29_RS29090_Epimerization.1"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="1421"
                     /protein_start="1109"
                     /score="414.3"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHFAVDG"
                     /tool="antismash"
                     /translation="GPFPATPIMHWFRELGGPVDGFSQSVVLQTPAALDERRLADLLQS
                     VVDHHDVLRLRMETRPDGSWSPEVRPVGSVRAVDLIRRVDTGGLGSERTAALLEREAAA
                     ADRQLRPARGDILRAVWCDAGDAPGRLLLTAHHFAVDGVSWRILLADLVTAWQAVLAGR
                     APALEPVAVPFRQWAQHLTDLAHDPAQTAQLPLWQRIASTASPLPSRVSPDPRRDLAGT
                     VRRHTRELPVDPTRALLTGVPAAFHAGMNDVLLTALTAAVVEWRRRRGTYATDLLLDLE
                     GHGRDEGAGTLDLSRTVGWFTTLHPVRLDLG"
     CDS_motif       15584..15649
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0010"
                     /evalue="3.00E-11"
                     /label="NRPS-E2"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="1261"
                     /protein_start="1239"
                     /score="35.5"
                     /tool="antismash"
                     /translation="LLLTAHHFAVDGVSWRILLADL"
     CDS_motif       16070..16120
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0011"
                     /evalue="4.20E-09"
                     /label="NRPS-E5"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="1418"
                     /protein_start="1401"
                     /score="28.3"
                     /tool="antismash"
                     /translation="DLSRTVGWFTTLHPVRL"
     aSDomain        16169..16639
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29090_TIGR01720.1"
                     /evalue="9.90E-40"
                     /label="A6A29_RS29090_TIGR01720.1"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="1591"
                     /protein_start="1434"
                     /score="127.8"
                     /tool="antismash"
                     /translation="LGRAVKRVKEQLNAVPQHGLGHGLLRHLNEDTAKELSTTAVPELC
                     FNYLGRFTAPDDTDWSPAPEIHLLGGSVDSGLPFGRSLQLNAYTRDTPDGPRLTALWSW
                     PGALWDDADIAELADSWFTMLRALVRHTATGGAGGHSPSDLPLVDLSQNDIDL"
     CDS_motif       16190..16252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29090_0012"
                     /evalue="5.80E-09"
                     /label="NRPS-E6"
                     /locus_tag="A6A29_RS29090"
                     /protein_end="1462"
                     /protein_start="1441"
                     /score="28.2"
                     /tool="antismash"
                     /translation="VKEQLNAVPQHGLGHGLLRHL"
     gene            16678..>19568
                     /locus_tag="A6A29_RS29095"
                     /old_locus_tag="A6A29_41480"
     CDS             16678..>19568
                     /NRPS_PKS="Domain: Condensation_DCL (7-303). E-value:
                     1.6e-108. Score: 354.3. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29095_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (463-854). E-value:
                     7.5e-105. Score: 342.8. Matches aSDomain:
                     nrpspksdomains_A6A29_RS29095_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="A6A29_RS29095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_41480"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_073724441.1"
                     /sec_met_domain="Condensation (E-value: 1.3e-62, bitscore:
                     201.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.7e-115, bitscore:
                     373.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESRIDDVLPLAPLQEGLLFLSRYDDATAADVYVVQFRFDIEGP
                     LDGDRMRAAAEALLVRHPHLRAAFRHQRREGRPVQVVPRSVRLPWDELDLSGLDPVERA
                     AELERVLSEDRSRRFDPARPPLMRFTLIRLGPRTHRLVFTHHHLLLDGWSMGLLIKELF
                     AAYEHGGDASALPATTPYRSYLTWLAHQDVPAARAAWSDAFDGLTEPTLVAGHGRPTGA
                     PAEYVTELPEDLTAALTSRGRAAGLTLNTLVQGAWGLLVGSLTGRDDITFGEIVSGRPA
                     DLDGAEAMIGMFANALPVRMRTAPGDSLARTLLRLQEQHGTLMPHQHLGLSAVQALAEP
                     AELFDTMVIFENYPLDPDTLHVTAGDIRLTELSEHAATHYPLCLMVLPGERLTLRLGYG
                     TDLYDERAAASLAERLLGLLELLSADLDRPLASIDPLPAAERWELLEARNDTARPVPAL
                     TLPGLFAEQARTTPDAVAVEAADGSLTYAELDRRSAALAQRLTALGAGPERHVALLLPR
                     TCDLLVALLAVLRTGAAYVPLDPHHPAERIGQVLTDVHPVCLLADRADGAAAQHGVPLL
                     HVDDEEHTCPPAPGDTCAAPDPAHPAYVIHTSGSTGRPKGVVVPHSALTNFLTDLRTRV
                     PLGPGDKLLAVTTVSFDIAALELFLPLLGGATVVLADQDTVLDPDALAHALTTSGACVM
                     QATPTLWRTLVTDHAEALRGLRVLTGGEPLPDDLATALTTAAGEVTNLYGPTETTIWST
                     VAEVRPGAPVTIGRPMGNTRVYVLDGGLRPVPVGVRGDLYVAGAGLARGYVGRGGLTAE
                     RFVADPFGVAGGRMYRTGDVAVWRGDGVLEFGGRTDGQVKIRGFRVETAEIEAVLRAHP
                     GVLDAAVVARSAPDTPVRLAGYVVPVPEEDPGTGVAETSAADSSRDTREHQQEKSWRDV
                     YDTLYQDLGDSPYAAWNSSYDGLPIAVGEMEEWR"
     aSDomain        16699..17586
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29095_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.60E-108"
                     /label="A6A29_RS29095_Condensation_DCL.1"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="303"
                     /protein_start="7"
                     /score="354.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLLDG"
                     /tool="antismash"
                     /translation="DVLPLAPLQEGLLFLSRYDDATAADVYVVQFRFDIEGPLDGDRMR
                     AAAEALLVRHPHLRAAFRHQRREGRPVQVVPRSVRLPWDELDLSGLDPVERAAELERVL
                     SEDRSRRFDPARPPLMRFTLIRLGPRTHRLVFTHHHLLLDGWSMGLLIKELFAAYEHGG
                     DASALPATTPYRSYLTWLAHQDVPAARAAWSDAFDGLTEPTLVAGHGRPTGAPAEYVTE
                     LPEDLTAALTSRGRAAGLTLNTLVQGAWGLLVGSLTGRDDITFGEIVSGRPADLDGAEA
                     MIGMFANALPVRMRT"
     aSModule        16699..19239
                     /domains="nrpspksdomains_A6A29_RS29095_Condensation_DCL.1"
                     /domains="nrpspksdomains_A6A29_RS29095_AMP-binding.1"
                     /incomplete
                     /locus_tags="A6A29_RS29095"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       16708..16743
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0001"
                     /evalue="6.10E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="22"
                     /protein_start="10"
                     /score="12.7"
                     /tool="antismash"
                     /translation="PLAPLQEGLLFL"
     CDS_motif       16771..16890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0002"
                     /evalue="2.80E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="71"
                     /protein_start="31"
                     /score="45.3"
                     /tool="antismash"
                     /translation="DVYVVQFRFDIEGPLDGDRMRAAAEALLVRHPHLRAAFRH"
     CDS_motif       17110..17175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0003"
                     /evalue="4.60E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="166"
                     /protein_start="144"
                     /score="38.3"
                     /tool="antismash"
                     /translation="HHHLLLDGWSMGLLIKELFAAY"
     CDS_motif       17482..17577
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0004"
                     /evalue="1.40E-15"
                     /label="C5_DCL_263-294"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="300"
                     /protein_start="268"
                     /score="49.6"
                     /tool="antismash"
                     /translation="DITFGEIVSGRPADLDGAEAMIGMFANALPVR"
     CDS_motif       17626..17739
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0005"
                     /evalue="8.70E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="354"
                     /protein_start="316"
                     /score="50.3"
                     /tool="antismash"
                     /translation="QEQHGTLMPHQHLGLSAVQALAEPAELFDTMVIFENYP"
     aSDomain        18067..19239
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A29_RS29095_AMP-binding.1"
                     /evalue="7.50E-105"
                     /label="A6A29_RS29095_AMP-binding.1"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="854"
                     /protein_start="463"
                     /score="342.8"
                     /specificity="substrate consensus: Gly"
                     /tool="antismash"
                     /translation="FAEQARTTPDAVAVEAADGSLTYAELDRRSAALAQRLTALGAGPE
                     RHVALLLPRTCDLLVALLAVLRTGAAYVPLDPHHPAERIGQVLTDVHPVCLLADRADGA
                     AAQHGVPLLHVDDEEHTCPPAPGDTCAAPDPAHPAYVIHTSGSTGRPKGVVVPHSALTN
                     FLTDLRTRVPLGPGDKLLAVTTVSFDIAALELFLPLLGGATVVLADQDTVLDPDALAHA
                     LTTSGACVMQATPTLWRTLVTDHAEALRGLRVLTGGEPLPDDLATALTTAAGEVTNLYG
                     PTETTIWSTVAEVRPGAPVTIGRPMGNTRVYVLDGGLRPVPVGVRGDLYVAGAGLARGY
                     VGRGGLTAERFVADPFGVAGGRMYRTGDVAVWRGDGVLEFGGRTDGQVKIR"
     CDS_motif       18253..18294
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0006"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="539"
                     /protein_start="525"
                     /score="17.6"
                     /tool="antismash"
                     /translation="LAVLRTGAAYVPLD"
     CDS_motif       18481..18540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0007"
                     /evalue="6.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="621"
                     /protein_start="601"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AYVIHTSGSTGRPKGVVVPH"
     CDS_motif       19030..19119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0008"
                     /evalue="4.20E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="814"
                     /protein_start="784"
                     /score="41.4"
                     /tool="antismash"
                     /translation="PVGVRGDLYVAGAGLARGYVGRGGLTAERF"
     CDS_motif       19210..19269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A6A29_RS29095_0009"
                     /evalue="1.10E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="A6A29_RS29095"
                     /protein_end="864"
                     /protein_start="844"
                     /score="30.5"
                     /tool="antismash"
                     /translation="GRTDGQVKIRGFRVETAEIE"
ORIGIN
        1 cgtcccccag ctcaccgaag agatcaacac ccgcaagggc tgacccccac accacaccac
       61 acgcaacaca gcacaccacg caacacacag cacgcaggcg caccaccccc cggggccgca
      121 cggtgaaacc caccgcgcgg ccccggacca ttaccggaca ccattgacgc aggtacgacg
      181 gccttataac ttcactatac ggattgttga ttccgggaag cggaaaaagc gagagcgtgg
      241 agggtacggg aatgggtcag caggagaagg tggcaacgag cctcgccggc acggtcggcg
      301 agcacatcag cgcctccctc gcggcagtgg acgccgaact cgcccgccgc tatccgggag
      361 accccggcac ccgccagccc gtgcacaccg tctacgtacc cggcgacgtg ttcgccgccg
      421 acaccatccg ctcctggggc gaccgggcgc tggaggccct cgacgcgcac gcccccgacg
      481 ccgcctcctt cgccgcggcc ctcggcatcc ccgaggaact ggccgggccc gtccacgacc
      541 gcgtacgcgc caagctggag cgcgagcccg tcgaggacct gcgcatcgac ttcgaggacg
      601 gctacggccc acgctccgac gacgaggagg acgaggcggc ggcccgcgcc gccctgctcg
      661 tctcgcaggc gtacggggac ggcacctcgg ccccgtacat gggtatccgg atgaagtgca
      721 tggaggccgc cgtacgcgac cgcggaatcc gcaccacgga tgtcttcctc accggcctga
      781 tgcgggccgg cgggcttccc gacgggctcg tgctgaccct gcccaaggtg acgtaccccg
      841 agcaggtcac cgccttcgtc cagctgctcg aagccttcga gaaggcccat gggctcgacg
      901 ccgggcggat cggcttcgag atccagatcg agaccagcca gtcgatcctc gcggcggacg
      961 gcaccgccgc cgtggcccgc atgatcgacg ccgcccgggg gcgggcgacc ggtctgcact
     1021 acggcacctt cgactacagc gcctgcgtcg gtgtcagccc cgcgtaccag gccggcgacc
     1081 acccggccgc cgaccatgcc aaggccgtca tgcaggtcgc cgcggcgggc accggcgtac
     1141 gcgtctgtga cggttccacc aacgtcctgc ccgtcggccc cacctcccag gtccacgagg
     1201 cgtggcggct tcactacgga ctcacccgcc gcgccctggc ccgcgcctac taccagggct
     1261 gggacatgca cccgggccac ctgcccaccc ggtacgcggc cgtctacacc ttctaccgcg
     1321 agggtctgga gcaggcggcg ggccgcctcg cggcgtacgt cgccaaggcg ggcggcgacg
     1381 tcatggacga accggccacc gccaaggccc tcagcggcta tctgctccgc ggcatcgact
     1441 gcggtgccct ggacaccgcc gaggtcgccc gtctcaccgg gctcacccgc gcggacctcg
     1501 acgcgttcgc ctcgccgcgc cgcggcgggc tgacggtcac cgccccgtag cggtccccgg
     1561 cgcggtcgct cccacggccg cgccggtgcg acggcgacgt gcgtacgggc gacgggcggc
     1621 ccgcacgccg tcggacggca tcaggcgggc gggcgttcgc ccgacccgcg cgcgatgagc
     1681 gtcgtcggga gttccacccg gaccggggcg tggtcgacgc cgtccaggcg gcggaagaga
     1741 tgctcggcgg cggtgcggcc gaccgccgcc gcgtcctggg agatcacggt gatgccgagc
     1801 agatcggcca gctcgatgtc gtcgaaaccg accagggcca cggggcgttc ccggtccgcc
     1861 aggacgcgta cgacggtcac cgtcacccgg ttgttccccg cgaacagggc ggtcaccggc
     1921 tccggtccac ggagcatcga ctcggcggcg tcccggaccc ggtcggggtc ggtggagccc
     1981 agcgagaccc aggcgtcctg gacctcgatg cccgcgtccg tcatcgccgc gtggtagccg
     2041 cgcagccgct cggtcgcggt gtggatgcgg ggctggtcac cgatgaagcc gatcctccgg
     2101 tggccgtgcg cgatcagatg ggcgacgcct tcgcgggcgc cgccgaagct gtccgagagg
     2161 accatgtcgg cgtcgatccg gcccgccggg cggtccacga agaccgtggc gatgcccgcc
     2221 ttgatctccg gctccagata gcggtggtcg tcgcctgcgg ggatcacgat cagaccgtcc
     2281 acgcggcggg cgcacagcgc gagcacgagt tcctgttcgc gctcggggtc ctcggcgctc
     2341 gaaccgttga tcaggagcgc gccgtgggca cgggcgacct cctccacggc gcggctcagc
     2401 gggccgtaga acgggtcggc gaggtcttcc aggaccaggc cgatggaggc ggtacggccc
     2461 ttgcgcagga cccgcgcgct gtcgttgcgg cggaagccca gggcatcgat cgcctcctgc
     2521 acgcggcgtt cggtgtcggg ggtgacgccc ggttcgctgt tcaccacccg cgagaccgtc
     2581 ttgaggccca ctccggcgcg ggcggccacg tccttcatgg tcggccggtt gccgtagcgg
     2641 gtctcggaat gacgggtggt ctcggccacg gtgcgctgtc ctgtcgtcgg tacggtcggc
     2701 tgtgagaggc tccggcgggt cccgcgaacg gtccgggaag gcgctggaag ggtgtggcgt
     2761 cgagcatagg ccctggacaa cgttgtcaga agaatagaga ctgtgcagac catcgactga
     2821 actcgcaggt cccgccccct cactcacccg gagagcccac accgatgcat accgacctcg
     2881 tcgccgcgct cgacatcgga ggcaccaaga tcgccggtgc gttggtggac ggcggaggaa
     2941 cccttctcgc gcgggcgcag cggccgacgc ccgctctgcg ggacgccgag acggtcatgg
     3001 cggccgtcgg cgacgtactg aacgagctga tggagtcacc gctgtggggc ggggccggat
     3061 ccgtgggcat cggcagcgcg ggccccgtgg atgcctcggc cggcacggtg agcccggtca
     3121 acgtcccggc ctggcgcgac tttccgctgg tggagcgggt gcgcaaggcg accggtgggc
     3181 tgcccgtggc gctggtcggc gacggtgtgg cgatgacggc ggccgagcac tggctcggcg
     3241 cggcccgcgg ctacgacaac gcgctctgcc tcgtcgtctc gacgggcgtc ggcggtggcc
     3301 tggtcctcgg cggcaggctg caccccggtc ccacgggcaa cgccgggcac atcggccacc
     3361 tctgtgtgga gctggacggc gacccgtgcc cgtgcggctc gcgcgggtgc gtcgagcgca
     3421 tcgccagtgg gccgaacatc gcccgccggg ccctcgacgg cggctggctc cccggcccgg
     3481 acggcgatgc cacggccgcc gccgtggccg ccgccgcgcg cgccggggac ccggtcgccg
     3541 tcgcctcgta cgagcgcgcc gcccaggcgc tggccgcggg aatcgccgcg accgccacgc
     3601 tcgtcgagat cgacatcgcg gtgatcggcg ggggagtggc cggtgcgggc gaggtgctct
     3661 tcgcgccgct gcgccggtcc ctgcgcgact acgccacgct ctcgttcgta cgccgcctca
     3721 cggtggcgcc ggccgtgatg ggcaccgacg cggggctggt gggagcggcg gccgccgccg
     3781 cgacggccgt gcgccggcca caggccctct gaacttccag ggggtgcccg gatccgtcag
     3841 gccggacacc ccctggacgg accgcgtcgg ctccgacgac gcgcggcccg cccgccgtta
     3901 cggctccggg cgtcggctcc gaggacaccc cggccgttcg ccgttacggc tccggcacgc
     3961 cgggcctcgt acagtgggat gcccgtcgac gggcacccgg ccgccacttc ccggcaacag
     4021 catcgccaca tcggggtttc cgcggcaggg tgttgcgggc aagccacagg gggctgcgga
     4081 agagggggat ccgtgatcgt ctgggccacc ggtgggtctt ggcaagtcgc tgctcagcgg
     4141 cttacctggg gaataccccg caagtgtctg gcctgagttg gcttgggtta gctctgccta
     4201 gccccaatgg gcaagatcct tctcccattc gtctcccggg ggcgaggccc ggtgaggtgg
     4261 aaggtgtccg cgccgggccg cagtccggtc gccccgcggc aggtgagcgg tgttacctag
     4321 gtcggcgggg tgctcccgct cgccccgcct cgggcctccg taaaccccag ccctgtcgca
     4381 tccggatgca atagcgtccc tgcctgtgag catcctcccg ccgcttcacc tggatactcc
     4441 cttcaagacc ctcacgggga acgccagtgc gcggcagcgg ccccagtcgc gtgcccgtcg
     4501 ccctccgcgc tcacccggac gtgtgacgtg tacgtcaggg acgcggagat caccgcaggt
     4561 agccggggag cagcgctccg gcgctggcga gtgccgccgt tcgagctgcg atgatgccga
     4621 cgtggcggtc gcacacggtc ttcggtccac gcccgggacg acgcctcgtc ccgtccatga
     4681 acatctgctc ctcgctgcca cctcccggag cgttttcttg tcattcgcgc agcacgaccc
     4741 gcaccgcgtg tcgtccacgg agcgccaccg ggtcgtgccg gtacccgggc gggggcccta
     4801 cggggtggcg gtcgccgacg acggggcgct ttgggtgacg ctcgccggat cgggtgacat
     4861 cgcccgcgtg cacagggacg ggcccgcacg ggtccatgcc ggtggtggag gcgcgggggc
     4921 gcgccccact tcggtggcgc ggggcagtga cggcgcgatg tggttcacgc agttcctcgc
     4981 ggacgcggtc gggtgcgtga ggcccgacgg gacggtggtg agcgttccgc tgccgaccag
     5041 gggcgcgggg ccgtacggca tcactgccgg accggacggc gccatgtggt tcaccgagat
     5101 gaacgccgac cgggtcgggc gcgtggacga cgaggggcgc gtggaggagt tcgtactgcc
     5161 ggtcgagggc gggtacccgt cggggatcac ggccggtgcg gacggcgccc tgtggttcgc
     5221 cctcaaccag gccgacgcga tcggacgcct cgacacggcc ggtcgcacca cggtccatcc
     5281 gctgcccacg agcggtgccg cgccggtcaa catcgccgcg ggcgaggacg gtgcgctgtg
     5341 gttcaccgag atcggcgccg ggcggatcgg gcggctgacg tacgacgggc ggatcgagga
     5401 attccgggtc tccgcgccgg acgcccgccc gcacgggatc gcggcggccg acgggggagg
     5461 atgctggttc accgagtggg gctcccatcg cgtgggccgg atgcggccgg acggacgggt
     5521 gcgcacctgg gcgttgcccg aagaggtcac ggagccgcat ggcatcgctg tcgcggggga
     5581 cggggtcgtg tgggcggcga tggagagcgg cgagctggtg ggggtgacac cgccggggga
     5641 gcagggctgg gggtgacgcc accgccccac ccggcgccgc ccgcggcccg ggatctcccc
     5701 gcccggtacg ccccccgcag ccctttcagg cgctcgccgc ggcctgcgcc cccccgctcc
     5761 ttcgccgacg acgcccggac caccgtcacc gaggccgggg aggccaggac cgtgagcgcg
     5821 gcggacatgg ccggtgcggt tccgaagcct tttcccgacg cgccgagcgc gaccccgacc
     5881 agcgccagga ctacctggac gaactggtcg tgcacaagcg ggaggagccg ggtgacgacc
     5941 tgctgagcgc gctcgtcgcc agcgcccagg acagcgagga cctcacggag cacgacgtcc
     6001 gttcgctctc cctcatcctg ctgctcgccg ggtacgaacc ggcgtcgaac cagctcggca
     6061 gcagcatcct gaccctgccg cgcttccccg accggctgaa gcaactgcgg gagaacccag
     6121 gcctcctgcc gacggcggtc gaggaactga tgcggtacgc gcccgcgggc gactgcgcgc
     6181 tcttccnnnn nnnnnnnnnn ncaccctcga cgagatcacc ctcggcgaca ccgtcattcc
     6241 cccctacagt gcggtactcg cgtccaccca ggccgccaac cgggacccgc gccgcttcga
     6301 ggaccccacc ggcctgcgtt tggaccggcc ggagaaccac cacaccgccc tggggcacgg
     6361 catccacttc tgtctgggcg ccgctttggc ccatgtcgca ctccaggtgg ccatcgggtc
     6421 gttgctgcgc cgcttccccg ggctcgcgct cgccaccgac gagcgcgagc tgcgctggtc
     6481 gagcccgggt tcgatgctca gcggcttctc cgagatcccc gtgacctggt gagcgcgccc
     6541 cgcccccggc acccacgggc agtgacgccg aagggctgat ggccacacct tcgtggtcac
     6601 cagcccttcg ggtcagggca gttgagccgc cgacgcagtc gggtcaggcc gcgtccgctc
     6661 ccaccgccgt ccgcagcacg ccgtcgcgca cctccatcgg ctccccggta aaccgggccc
     6721 gcagccgacg gtcgtgcgac acgatcacga ccgcgccctc gaacagcgcg agcgcctcct
     6781 ccaattcctc gatcaaggtc agcgccaggt ggttggtcgg ctcgtccagc agcagcaggt
     6841 ccgcgggttc ggtgaccagt cgggcgagcg tcagccgccg ttgctggccg atcgacaggc
     6901 cgcccaccgc gacgcggaag ctgtccggcg agaacaggcc gagcgaggcg agctgctcct
     6961 cgtgctcctc ccgcgtaccg acccggccct cggcgaacgc ctccagcagg gtctgccggg
     7021 gccggctcac cgacacctcc tgcggcaggt aactgatgcg gccctgccgt gtcacctggc
     7081 cggagtccgg ctcctgcaca cctgccagca gattcagcag cgtggtcttc ccggcgccgt
     7141 tggggccgtg gatcagcagc ctgcgccgct tgtcgatggt cagcccgtcc acccgcagcc
     7201 ggtggtcgac cgtcacgtcc gagagggtca ccagcggatg ttcgaaggtg cgccccgtgt
     7261 ccgtgagtcc ggcggtgaag cgcagcgggt ccggcggccg ggggaccggg ttctcctcca
     7321 ggcggcgcag ccgctccagc gagttgcgta cccggctgcc cacctggcgc tcggcccgca
     7381 gaccgtggtt gaagtactgg agcttgttgg agtggaagcg gttcgcgtag ccgacgcggt
     7441 gcgcggtggt cacgctgcgc acccgctgga attgcatgtc gtccagccag gtccggtact
     7501 cctcctccca gtggcggcgg gcggcggcct tctccgcgag gaacccggag tagccgttgc
     7561 cgaagcggtt caccgtgtgg cgctcgccct gcacctccag gatggtgtcg gtcacccgct
     7621 ccaggaacac cctgtcgtgg gagaccgcga cgacggtgcc ggggaaggcg cgcagccggt
     7681 cctccagcca ggccatggcc ttgtcgtcga ggtggttgga cggctcgtcg aggagcagca
     7741 gccccggctc cgtggcgagc gtgcaggcca gggcgagcct gctctgctcg ccgccggaca
     7801 gtgcgctgag cggacggtcg aacgggatgt gccccacgcc gagttcgtcg agcgcggctt
     7861 cggcgcgcgc gtccgcctcg tagccgccgc gcgcctcgaa gcgggtcatc aggttgccgt
     7921 agtcgtcgag ttcggcctgg gtggcgtccg ccatccgggc ctcggcggcg tgcaggtcgc
     7981 gttccatcgt gcgcaggtcc gacagggccc agtcgatggc gtcgcgcacc gtgcaatgcg
     8041 gtggcaggtc cagcgtctgg ccgagcagac cgattccccc actgctgtcg acggtgacct
     8101 cgccctcgtc gggctggtcg acaccggcca tcagccgcag cagggtcgtc ttgcccgcgc
     8161 cgttctcgcc gacgatgccg acgacgtcac cgggcttgat gctgagcgag acgccttcga
     8221 gcaccggatg gtcgacgtaa cccttggaca cgttggtgag agtgagctga gttgacatac
     8281 gcggatctcc tccggggcgc cttcacgcgc ccccgacagc ccagggagcg gcctgacgta
     8341 tacctgccgg aacggctggt gacaggccgc cgaggcggcg gaccggcggg agacccgcac
     8401 ggtgcgcggc gtgggcggat ggctgtggtg gtggtctgag gactcgccta cccagtcaga
     8461 agatcatggc cccagtgtaa cgaccggatt cggggatcga cagcggtttc cggccccggc
     8521 ccgccccccg ggcatcccgg acagccggtg gacgaacccc gccgatcaag gcggacaagg
     8581 gttctcggtg cccgtgcggg gctgtctgcg acccggcggg ccaccggcgc ggcacatggc
     8641 tcgcaggccc ctcgaaccct ctgccaccag cgaggggacg gccccggcca caggcccgta
     8701 gccgggccga tggccggtcg ccggcgagcg gacggcgtcc ccggcaccgg ctggtccctg
     8761 tcggccgcgc agcagaaccg cgcaggacgc ccgaagctca gcatggccgg ttccggaggg
     8821 tggatcaccg gagcgcgttc gcggcagcgg tcggcgccgc ccggccccgg cgcgccgtct
     8881 gcgcaggtca tctctcgtcc tggtggagct gggccacggc atccaggatg cggtccacgc
     8941 cgggtaggtg gtggcgctcc agcaacggcg gcggatacgg gacgtcaagg cccgtgaccc
     9001 gcagcaccgg ggcctccagg tgagagaagc agcgctcggt gaccgggccg cgatctccgc
     9061 cccgaccccg gcgaagccgc tcgactcgtg caccacgacg gcccggccgc acgcgcgcac
     9121 cagatggcag acgctctcgt cgtcgaaggc acgagcgtgc gcaggccgag caccgccagg
     9181 tcccagccgt gtgcccgcgc cgcctccgcc gcctccaggc acaccggcag ggacggggcc
     9241 gtacgtgagg aggacggcgg agccgccagg acggcgcagg acggcatgcc ccagcggctc
     9301 cacggcgggc ggcgcgtgct cgtcccaggg ctccttcgcc cagtagaggc gcttgggctc
     9361 cagcaccacc acggggtcgt ccgactcgat ggcggcgcgc agcagaccgt acgcgtccgc
     9421 cacggtcccc ggagtgacga cgtgcaggcc ggcgtgtgga cgtagtaggc atccgaggag
     9481 tcgctgtggt gctcgacccc gccgatgcca cccccgtacg ggatgcggac cacgagcggc
     9541 aggggcagcc gtccggcggt ccggttgcgc atcttcgcca catggcccac gagttgttcg
     9601 aaagcggggt gggcgaacgc gtcgaactgc atctccacca ccgggcgtag cccgtacatg
     9661 gccatatcca ccgccgtgcc ccgggatccc ggccatcggc agggccgggg gcccggacgc
     9721 ggcgggggtg gccatcgggg gcaggcccgt gggggccggt gaatgctcaa cggccgtcat
     9781 gtactgacac ccccttcggg cgcgtggacg tccgcccctg ccgcccctgc cgaacagccg
     9841 tgcgccgcac cgtcccatcg gtcggccgcg gactcgcggg cgtgcagcgc ggctacctgc
     9901 gcacgtagtt gaggagtcgg ccgcgcgtag atgtgcgcga acagcgcttc cggcgcggcg
     9961 tgttggggca cggtgaacgc ggcccgcagc tcggccgccg tgcggtcggc ggcctcgccc
    10021 gccgcgttcg cggtcgcctc gtggcgggcc agcggtacgg agatcgcgca gccgttgttc
    10081 tggacgagga agacgacggg cgccctgagt accccggcga aggtcagcgc ctcatggaag
    10141 tcgccctcgc tggtggcccc gtcgcccgcg agcgacagag ccaccatgtc gtcgccgcgc
    10201 agccgggcgg cgtgcgccag gccgaccgcg tgcggcaggt gtgtggccag cggggtgcac
    10261 agcggggcgg tgcgccaccg ccaggggtcg taaccgctgt ggacggcgcc gtgcagcagc
    10321 gccagggtct cgtcggccgg ggtcccccgc agatgcacgg cgagggtgcc gcggtaggtg
    10381 gggaagagcc agtcggtgga gcgcagggcc gaggccgcgg ctacctggca cgcttcctgc
    10441 ccggtcgacg acgggtagac ggcgaggcgt ccctgccgcg ccgacgtcga tgcctgctcg
    10501 ttgaacccgc ggcccacgac caggcggcgg tgcagggagc gggcgagggc ggggcggacg
    10561 gcggcggccc gtggagtgcc gatgatccgt acgggggacc gatcgggcag cagggggccg
    10621 ggtcgcgcag cgggccgtcc gcgccgggcc gccagaccgg ggttccgggg gaggccgcgt
    10681 cctcgggggc ggtccgggcg ccgtgcgggg gctcgggcgg ggcctcggct cgggtggcca
    10741 ttcacagcct cccggagagc ggactcagcg gccggtagtc gcgcgcggcg aggaactcgg
    10801 gccggggcgc ggccacttcc gccagctgat tggcgacgct gttgtaggtg atcaacgcca
    10861 ccgtccggtc gcccggcgac atgttggtcc cggaaccgtg cacgatccgg gggtcgaaga
    10921 agagcaggtc cccggcgcgg ccggtggccg acctgatgcc gtgcttctcg accaacggcc
    10981 tcagatggtc accgcgcagc cggaagtcca ggtccgccga caggttggag gcccattccg
    11041 gcttttcgga atccaccgtg gaatgcgctg ttcctgacgt cccggcagtc ccccggaatg
    11101 cgttggacgg atcatcggag aatgcgttgg ggtcagccgg agaatcactc tccgggagat
    11161 tctttgggac gttctccata tgtgaaccag gaatgaggag aagcggcccg ttgaattcgg
    11221 tgacatcgtc caggaagagc gctgcattga tggccttcgg ctgctgcatt ccgtctttct
    11281 gttcccagaa gacatagtcc tggtgccagg gccacacgtc gccgtccagt gctcgcttgg
    11341 cattgacctt gacctggtgg acgtagacgt cgtcctccac gaggcggcgg gccacggaca
    11401 gcatcgacgg cagccgcacc agccgggaga acaggtcgct cacctgatgg cagccgtgaa
    11461 ttccccggac ggtgctgccg tccttctcca gtatgcgccc ggggtgttct atcccttcca
    11521 gacgctggac ctcctcgcgt atgcggtcca ggtcgtccgg ttcgatgccg ctgtcgaggg
    11581 tcaggaaccc gtcggatcgg taggtgttga tctgcgcgga actgagcatt ttcgtcaccc
    11641 gtcgtgtccg gtctgatcgt ttcgggaggg tgcttcggag cctagcatcc agcctgcggg
    11701 agaacagtgg ggaaaggtat tccaccgcat catcgataac cttcgcagct tttcgtcagg
    11761 cgtccgtcag tcagaaatca gcggcctttg tgaggatgcc aagacgtaat tccccccacg
    11821 ggtgcgtacg aggcgccgac gaccggatca cgagcgagga gtcgatgtga cgcgtacggg
    11881 tacgggcgcc gggctgacgg acgtgctgcc gctgtctccc ctccaggacg gcctgctctt
    11941 ccacgcgctg tacgacgagg cggacgcgga cgtctacgtc gtgcagttcg tcctcacctt
    12001 gagtggcccg ctggacgccg cccgcctgcg cgccgccacc gaaggactgc tgcgccgcca
    12061 cccgaacctg cgcgccgggt tctggcagga cggcatgaaa cgggccgtcc agatcatccc
    12121 ccgggaatcc gtactgccct ggaccgagca cgacctgacg gggaccgcgc cggacgtgcg
    12181 cgaggacgcg ttccaacggc tcctcgacac ggaccggggc cgccgcttcg acccggcgca
    12241 ccccccactg atgcgcgccg ccctcgtcgc cctggggccc gaggaacacc ggttgctgat
    12301 cagccaccac cacctgctgg tcgacggctg gtccatgccc ctgctgctgg ccgacctgtt
    12361 caccctgtac gagaacggcg gcgacgagcg cgccatgacc ccgccgccct ccttccgcga
    12421 ccacctcgcc tggctcgcct cgcgggacgc ggaggcggac cggcgggcgt ggcgcgagga
    12481 actggcgggc ctcgaccacc ccaccaccgt gaccgccgcg cccggaaccg ccgtccccgc
    12541 gccccgcacc gccaccacgg acgccgtcgg ccccagggag gacgccgccg caggcgcacc
    12601 caccggcccg gacgtcactg gtgcaccgga cgcgcccgcc gacgggcgcc ccaggggagc
    12661 acggcatcag gaccccgtcc accagcagtt cgtcgaactg gacgagccca ccaccgccgc
    12721 cctcaccgcg caggggcgac gccacggact caccctcaac accctcgtcc agggagcctg
    12781 ggggctgctc ctcggagccc tcaccggaag ggacgacgtc acgttcgggg ccgtcgtctc
    12841 aggccgctcg cccgaggtcg accgctccga gaagatggtc ggcctgttca tcaacacggt
    12901 gccggtacgg gtgcgcaccc gggcgggcga caccctggcc accaccctcg gcacgctcca
    12961 ggaacaccag gcccggctgg cggaacacca gttcacgggc ctgtccgcga tccagcgcgc
    13021 ctgcggcatc cccgaactct tcgacaccct cctcgtgttc gagaactacc ccctggaccc
    13081 cgacgccctc gacctgcacg ccgacggact gcgcctgtcc gacctggaga tccgggaccg
    13141 cacccactat ccgctcagcc tggtcgtcat ccccggcgag accctgcggc tgcgcgtcga
    13201 gcaccgcgcc gaccgctgcg cccccgaggt ggctcgcgac ctgggaccgc gcctgctacg
    13261 gctgctgcgc gccatggccg acggtctgga ggagccggca gcccgcctcg acctgctctc
    13321 gcaccaggag cgcgccgcac tcctcgacac cccccgggaa cccgcccacg cgctgtccgg
    13381 ccggaccctg cccggactgc tcgaccagca ggccgcgctg acgcccgacg ccctcgccgt
    13441 cgtctgcgcg gacgagcggc tgacgtaccg cgaggtggcg tcgcgctcca accggctggc
    13501 gcgcctgctg atcagccggg gcgcgggccc agagacgctc gtggcgctcg ccctgccgcg
    13561 cggcaccgaa caggtcgtcg cgttcctcgc cgtcctcaag gccggcgccg cctacacccc
    13621 cgtcgacacg tcctacccgc aggagcgcgt ctgcttcctc ctcgcggacg ccgcccccgt
    13681 cgccgtggtc accaccgccg ccgaggccca cctgctgcca ccgggcgcgg aacccgtcgt
    13741 cctggacgct cccgctttcg ccgcggaact cgccgcctgc tccgacgccg acctcaccga
    13801 cgccgaacgc ctccaccccc tgcacgcgga ccacccggtc tacgccctct acacctcggg
    13861 ctccaccggc cgccccaagg gcgtcctcat gcacgccgag ccgctgctca acctcatggc
    13921 gtggtatgcg cggaccgtgc cgggggagcc gggtgccgtc gcctcgcagt tctcgacgac
    13981 ggccttcgac cccgccccgc tggagatgct ctccgcgctc acccagggcc agactctcac
    14041 cgtcgccacc gacctggccc gccacgaccc gcaggaactc ctcgactggc tggaacgcga
    14101 gggtgcccgg cacctctaca ccaccaacac cgtcgtcgaa gcgctcgccg acgccgccgc
    14161 cgcgaccggc cgcaccctgc ccgacctgcg agaggtcgtc caggcagggg aagccctgat
    14221 gccctcccag tacgtcaaac ggctcttccg cgaccacccc gggcgacggc tgcacaacct
    14281 ctacggcccc accgagaccc acgtcgtcac cgcagccgtc ctcggccccg accccgacgc
    14341 ctggccgcac tcggcgccca tcggcaccgc cctgccgcac acccgggtgt acgtgctcga
    14401 cacctggctg cgcccggtgc cgcccggtgt ggcgggcgag ctgtacgtcg gtggggtcat
    14461 gcccgcgcgc ggctatgtgc gccgcgcggg tctcaccgcc tcccgcttcg tcgccgcccc
    14521 gttcgggccg cccggcggac gcctctaccg caccggcgac ctggtgcgtc aacgccaggg
    14581 cggagcactg gacttcctgg gccgcgccga cgaccaggtc aagatcggcg gccagcgcgt
    14641 cgaacccggc gagacccggg cagcactcga agcgctcccg gacgtcgcac aggcgcacgt
    14701 caccgtccgc gaggacaccc ccggggtccg ccgcctggtc gcctacctgg tcgccgcccc
    14761 cggaacgcac cccgtccccg ccgacctgcg cgccgcgctc gcccgcaccc tgcccgcccc
    14821 gcaggtgccc gccgactgcg tcctgctcga cgcgctgccc cgcaacgcca acggcaaggt
    14881 cgaccggagc gcgctgcccg cccccgtggt ggccggggac gccgccggac gtgccccgcg
    14941 caccgacgcc gagcgcttgc tcgccagact cttccaggag gtcgtgggag ccaccgccgt
    15001 aggggtcgac gacagcttct tcgctctcgg cggtgacagc atcatgtcga tgcagctcgc
    15061 cggtcgggcc cgcaaggaag ggctgttctt ctccccgcgc gacgtcttcg aacagcgcac
    15121 cgtggccctg ctcgccgccg tcgccacccc ggccgacgac cgggcggcgg gccccgcccg
    15181 caccgagggc tccgggccct tccccgccac tccgatcatg cactggttcc gcgaactcgg
    15241 cggccccgta gacgggttca gccagtcggt cgtcctccag acgcctgccg cactcgacga
    15301 acgccgcctg gctgacctgc tccagagcgt cgtcgaccac cacgacgtgc tgcgcctgcg
    15361 gatggagacc cggcccgacg ggagttggtc ccccgaggtc cggcccgtcg gctcggtgcg
    15421 cgccgtcgac ctgatccgcc gggtggacac cgggggactg ggctccgaac ggaccgcggc
    15481 actgctggag cgcgaagccg ccgccgccga ccgccaactg cgccccgccc ggggcgacat
    15541 cctgcgcgcc gtgtggtgcg acgcgggcga tgcccccggc cgactcctgc tcaccgccca
    15601 ccatttcgcc gtcgacggcg tgtcctggcg catcctcctc gccgacctcg tcaccgcctg
    15661 gcaggccgtc ctggcgggcc gcgccccggc gctcgaaccg gtcgccgtcc ccttccgcca
    15721 gtgggcccag cacctcaccg acctggccca cgaccccgcg cagaccgccc agctcccgct
    15781 ctggcagcgc atcgcgtcga ccgcgtcccc gctgccctcc cgggtctccc cggacccccg
    15841 ccgcgacttg gccggcacgg tgcggcgcca cacccgggaa ctcccggtcg accccactcg
    15901 cgccctgctg accggcgtcc ccgccgcctt ccacgccggg atgaacgacg tcctgctcac
    15961 cgcgctcacc gcggccgtcg tcgaatggcg ccgacggcgc ggcacgtacg ccaccgacct
    16021 gctcctcgac ctcgaaggcc acggccgcga cgagggcgcg ggaaccctcg acctgtcccg
    16081 taccgtcggc tggttcacca ccctgcaccc ggtgcgcctc gacctcggcc gcaccgacca
    16141 ccgcgaactc ggcgcgggcg ggccggccct cggacgagcc gtcaaacgcg tcaaggaaca
    16201 actgaacgcc gtcccccaac acggcctcgg ccacggactg ctgcgccacc tgaacgagga
    16261 cacggccaag gaactctcca ccacggccgt ccccgagctg tgtttcaact acctggggcg
    16321 cttcaccgcg cccgacgaca ccgactggtc gcccgccccc gagatccacc tgctcggcgg
    16381 ctccgtcgac tccggcctcc ccttcggccg ctccctccag ctcaacgcct acaccaggga
    16441 cacgcccgac ggcccccggc tcaccgcctt gtggtcctgg cccggagccc tctgggacga
    16501 cgcggacatc gcggaactcg ccgacagctg gttcaccatg ctccgggccc tggtccggca
    16561 caccgcgacc ggcggcgcgg gcggacactc cccctccgac ctgcccctgg tggatctcag
    16621 ccagaacgac atcgacctgc tcgaaagcga actgggcgag gaagacgagg aatcgaagtg
    16681 accgagtccc ggatcgacga cgtactcccg ctcgccccgc tccaggaagg actgctgttc
    16741 ctctcccggt acgacgacgc gaccgcggcg gacgtctacg tggtgcagtt ccgcttcgac
    16801 atcgaaggcc ccctggacgg cgaccggatg cgtgccgccg ccgaggcgct gctcgtccgc
    16861 cacccccacc tacgggccgc cttccgccac cagcgccgcg agggccgccc cgtccaggtc
    16921 gtcccccgct ccgtccgcct gccctgggac gaactggacc tcagcggtct cgaccccgtc
    16981 gagcgcgccg ccgaactgga acgcgtactg tccgaggacc gctcccggcg cttcgacccg
    17041 gcccggccgc cactgatgcg cttcaccctg atccgcctcg gcccgcgcac ccaccgcctg
    17101 gtcttcaccc accaccacct gctgctcgac ggctggtcga tgggcctgct gatcaaggaa
    17161 ctcttcgccg cgtacgaaca cggcggcgat gcctccgcgc tgcccgccac cacgccctac
    17221 cgctcctatc tgacctggct cgcccaccag gacgtgccgg ccgcccgtgc ggcctggagc
    17281 gacgcgttcg acggcctcac ggagccgacc ctcgtcgcgg gccacggccg ccccaccgga
    17341 gcacctgccg agtacgtcac cgaactgccc gaggacctca ccgccgccct caccagccgt
    17401 ggccgggccg ccggactcac cctcaacacc ctggtgcagg gcgcgtgggg cctcctcgtc
    17461 ggcagcctca ccggacgcga cgacatcacc ttcggcgaga tcgtctccgg acggcccgcc
    17521 gacctcgacg gcgccgaggc catgatcggc atgttcgcca acgcgctgcc ggtacgcatg
    17581 cgcaccgcgc ccggcgactc gctcgcccgg accctgctgc ggctccagga gcagcacggc
    17641 acgctcatgc cccaccagca cctcgggctc agcgccgtcc aggccctcgc ggaacccgcc
    17701 gagctcttcg acaccatggt catcttcgag aactacccgc tcgaccccga cacgctccac
    17761 gtcaccgcag gcgacatccg cctcaccgag ctcagcgagc acgccgccac gcactacccg
    17821 ctgtgcctga tggtgctccc cggcgagcgg ctgaccctgc gcctcggcta cggcaccgac
    17881 ctctacgacg agcgcgccgc cgcctccctc gccgagcggc tcctcggcct gctcgaactc
    17941 ctctcggcgg acttggaccg cccgctggcc tccatcgacc cgctgcccgc cgccgaacgc
    18001 tgggaactgc tggaagccag gaacgacacg gcccggcctg tgcccgcgct gacgctgccc
    18061 ggactcttcg ccgagcaggc ccgtaccacc ccagacgccg tggccgtcga agcggcggac
    18121 ggttccctca cgtacgccga gctcgaccgc aggtcggcgg cgctcgccca gcgcctcacc
    18181 gcgctcggtg ccgggcccga acgccatgtg gcgctgctcc tgccccgcac ctgcgacctc
    18241 ctggtggcgc tgctcgccgt gctccgcacc ggcgccgcct acgtaccgct cgacccccac
    18301 cacccggccg agcggatcgg ccaggtactg accgacgtcc accccgtgtg cctgctcgcc
    18361 gaccgcgccg acggcgccgc cgcacagcac ggcgtccccc tgctgcacgt cgacgacgag
    18421 gagcacacgt gtcccccggc cccgggggac acgtgtgccg cgcccgaccc ggcgcacccc
    18481 gcctacgtca tccacacctc gggctccacc ggccgcccca agggcgtcgt cgtaccgcac
    18541 agcgccctga ccaacttcct caccgacctg cgcacccgtg tgccgctcgg ccccggcgac
    18601 aagctcctcg ccgtcaccac cgtctccttc gacatcgccg cactggagct cttcctgccc
    18661 ctgctcggcg gggccaccgt cgtactcgcg gaccaggaca ccgtcctgga ccccgacgca
    18721 ctcgcgcacg cgctcaccac ctccggcgcc tgtgtcatgc aagccacccc cacgctgtgg
    18781 cgcaccctcg tcaccgacca cgccgaggcc ctgcgcggcc tgcgcgtcct gaccggcggc
    18841 gaacccctcc cggacgacct cgccacggcc ctgaccacgg cggccggcga ggtcaccaac
    18901 ctctacgggc ccaccgagac caccatctgg tcgaccgtcg cggaagtgcg tcccggcgcc
    18961 ccggtcacga tcgggcggcc gatggggaac acgcgggtgt atgtgctgga tggtgggttg
    19021 cgtccggtgc cggtgggggt gcggggggat ctgtatgtgg cgggtgcggg tctggcgcgt
    19081 ggttatgtgg gtcgtggggg tttgacggcg gagcgtttcg ttgctgatcc gttcggtgtc
    19141 gctggtggtc ggatgtatcg cacgggtgat gtggcggtgt ggcgtggtga tggggtgctg
    19201 gagttcgggg gacgtacgga cggtcaggtg aagatccggg gcttccgggt ggagaccgcc
    19261 gagatcgaag ccgtactgcg cgcgcacccc ggcgtcctcg acgccgccgt cgtcgcccgg
    19321 agcgcgcccg acaccccggt ccggctggcg ggttacgtcg tccccgtacc cgaggaggac
    19381 cccggcacgg gcgttgccga gacctccgcc gccgacagct cgcgcgacac gcgcgaacac
    19441 cagcaggaaa agtcctggcg cgacgtgtac gacaccctct accaagacct cggcgacagc
    19501 ccgtacgcag cctggaacag cagttatgac gggttgccga tcgcggtggg ggagatggag
    19561 gagtggcg
//
