LOCUS       NZ_LWLE01000001        21044 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces sp. TSRI0281 scaffold1, whole genome shotgun sequence.
ACCESSION   NZ_LWLE01000001
VERSION     NZ_LWLE01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TSRI0281
  ORGANISM  Streptomyces sp. TSRI0281
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1430136)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430136)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905125.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:37:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,600
            CDSs (total)                      :: 8,518
            Genes (coding)                    :: 8,175
            CDSs (with protein)               :: 8,175
            Genes (RNA)                       :: 82
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 345
            CDSs (without protein)            :: 343
            Pseudo Genes (ambiguous residues) :: 0 of 345
            Pseudo Genes (frameshifted)       :: 151 of 345
            Pseudo Genes (incomplete)         :: 273 of 345
            Pseudo Genes (internal stop)      :: 33 of 345
            Pseudo Genes (multiple problems)  :: 102 of 345
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:13:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 94474
            Orig. end                         :: 115518
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWLE01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11044)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    879..894
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    920..931
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.78"
                     /tool="antismash"
     gene            927..2240
                     /locus_tag="A6A29_RS00440"
                     /old_locus_tag="A6A29_00435"
     CDS             927..2240
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984584.1"
                     /locus_tag="A6A29_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00435"
                     /product="hypothetical protein"
                     /protein_id="WP_241838275.1"
                     /transl_table=11
                     /translation="MSAVERPVGLVPARSCPPVQPLRPTPREHRDPGQWVTLTGCRKVL
                     MVVHTEVYGQRLRDLLPLVESDLRIQVAFTIAPHAFNGGAVRSLPAEGTTVIPWEEAVR
                     TEFDLALAAGSQGMEQVRAPLIRMPHGIGHMKLSRAADGPEGAPRTVGGLGRKYLMRDG
                     RVVPRSIVLAHREDLAELGRWCPEALPAAEVVGDASHDRLAASLPLREHYRRAMGLKPG
                     QRLLLVSSTWGTGSSFNRLDALLPRLLAELPRDAYRIALLVHPNVWSGHGRWQVHAWLE
                     AFRRRGIAIVPPEADWRAALIASDWLIGDHGSVTLYATMTRARILLARFPEADVNPLSP
                     GAELARTAPALSPAHPITEQLAYADAEYPAAEYARIAARISSEPGQFNQRMRGVLYRML
                     GLGQPAFAPATRPLPLPAPLDPAPSADPWGADGTEISA"
     gene            2237..2704
                     /locus_tag="A6A29_RS00445"
                     /old_locus_tag="A6A29_00440"
     CDS             2237..2704
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A29_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A29_00440"
                     /product="hypothetical protein"
                     /protein_id="WP_073717893.1"
                     /transl_table=11
                     /translation="MNGDTTANGGEDGRPLCVDLDGPAGESWRQCADVLHGGRPRPARE
                     AARVARQALVRYPGCLLTVVSRTDGGCTTASWLDGRPSVRVYAPGRVRPGRGTTRLVAE
                     LYAKLIDEAAPRPDPAVAPGQGFRTAPACSGDRVSGPLLPGGPEDAGHHPR"
     gene            complement(2649..4832)
                     /locus_tag="A6A29_RS00450"
                     /old_locus_tag="A6A29_00445"
     CDS             complement(2649..4832)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353197.1"
                     /locus_tag="A6A29_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00445"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_079182518.1"
                     /transl_table=11
                     /translation="MEPVPGSGHTADGGRGGVRGPNIQDNTVSGDATLSGPVVQAHGIH
                     GGVHFHSAPEPAVATARQLLPAPPYFLGRESELGSLREMAGRLPSAPVLAVISGPAGVG
                     KTALASSWLRGMGEQFPDGQFYADLRGHSATGSPAPPAEILAQFLRALGLTQVPQGLGE
                     LAALWRTRTAGRRIAVMLDNAVSAGQVRPLLPGTEGSLVAVTSRFRLAGLAVDGAVFQQ
                     LGVLDTEDTVELLSRRIGSDRVGREPEAAREVAALCAGLPLAVCIAAARMAVRPRQPLA
                     AMALALGGDGGLDTLKVEGEPAVRAALDASYRLLKPDLALGYRRLGILPVSVFSVRVAA
                     AACGADPLEADRIVDALAEVNLLEDLGPDPVTGLDRFRFHDLVRAHAGALAEADESPED
                     RRRTVRRVVDLYLRTATAAEALLSPSHRTLRRDYACDREQPTPFDDATGALEWLDAERT
                     HLMAVLRRAADLGWDAAVWQLADAMWPLFLRLRPYDLWIEAHEAGLAAARRAGDPQGES
                     RMLTSGGTGLRNVGRHDEAVAWFTRAAEAALRDQDSVAEAQALHGAGQSHRLAGRLTEA
                     RSFFVRALALREAAGYRRGVALTELCLGDVELAEGRPERALGHLSRARAVLLDVRDAYD
                     AARALAHLARAHAGVGDFALAAGELAMALGEFEATGSVHWQGRVLEMLGETAAERGEGA
                     EARGWYEQSLARYASVSADDVRRLQDRLGGAAR"
     misc_feature    complement(3441..3443)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4569..4571)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4979..4992
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    complement(4980..4993)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.57"
                     /tool="antismash"
     gene            5050..8181
                     /locus_tag="A6A29_RS00455"
                     /old_locus_tag="A6A29_00450"
     CDS             5050..8181
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135599.1"
                     /locus_tag="A6A29_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00450"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_241838276.1"
                     /transl_table=11
                     /translation="MGRGDDGLPWPQTGARRHERNSRAERGPAMGALVEFEIRILGSIE
                     LRVDGRRDPLGTAKERAMIAALAVDAGRPVALDSLVHRLWDDAPPAKPRASLHVYAARI
                     RRRLGERAGGPTRIVQQAHTYSLVVDPDSVDSHRFQRLTAEALARSDDGDGPRALALLR
                     EADSLWRGDPLTGMPGLWAESVRTNLLEKRLAATLARVGIELRTGRYAELVPDLSTLFE
                     LHPTDETLAGHLMVANYGCGRQADALRTFDTVRRRLGEEFGSDPGEALTRLYQLILNRV
                     PVSGLLSGPEPVTTAPHTLPSHGDLVGRDREMLTLLARPPAGSVIALQTISGMGGVGKT
                     LLALHAARALAPHYPDGQLHLDLSAHTADGHPLSPESALTRLLRDFGVPVTDLPDDLEG
                     LVSLWRTLLSTRRSVIVLDDAADAEQVAPLLPGTSESLLIITSRRRLTGLPGIRSLFLD
                     VLPADDASTLFRRLVGPERTSDLDEVADIVRLCGHLPLAVEIAAGRLGSRPSWTTSHLI
                     EKLSREHGRLNEIRDGYRKIAGVFEMSYHTLGTEERTIFRQLSLHFGPDFTPHSAAALT
                     GLPLEETERVLDSLLDAHLLQEPAPERFRFHDLVGECARSLSATEDRYEGQLPAVRRMI
                     DFYVHGAEKADRLIYPRRLKVDIEEAATEFALPEWQDASAARHWLVQEHGALVAAEHRA
                     RGNGLTRQAARLAHALAAHLDEEGYWGEARPMHTAAAEFWHESGERRPEALALIDLGTT
                     LARAGRYEAALAAGHAAMRAAGTLDDPATDAEARHLLGVIHWHMGQLDEALSFQNQTLE
                     RRLRSGDIWQLARTRNNLGITHLFLGNHTTSMEFFVSALGGFRRSGDAREEFNVLNNLS
                     DLHFQTGDRESARRLLKKSLSNPRLAGTPLARATGQVNLANTMEMPEEVEAALDLYREA
                     LLSFRQLGDRRNASITLHRMGVAFEESGNDDQAVAHHERALDLATGIGAGHERMLALRG
                     MAAAERRLGRTQSAARHLAEALTLAQHIGAMDEAARTQAEFAALQEESEGAGTE"
     gene            complement(8591..9259)
                     /locus_tag="A6A29_RS00460"
                     /old_locus_tag="A6A29_00455"
     CDS             complement(8591..9259)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959109.1"
                     /locus_tag="A6A29_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00455"
                     /product="DUF6304 family protein"
                     /protein_id="WP_073717894.1"
                     /transl_table=11
                     /translation="MTDESWAGWYRDREGSDAVVLTTDGQQLRIRIRGVDFEGESFDDL
                     VPVGGIPPESGMFALADGALTDCVLEWDLPLPVRSAGTVRQATLSCLLSLRRSDPDLYL
                     ALHLDGAVYESARAERDFAAAMATIQRILPSGTQVQTCIACAFSDYFPAPGRGLSGALA
                     CFRGAKDAYRGAAGEDDVLDLWDRRSGFVQEIWSCREFEARPAEGAGTGHRGAFPLELA
                     "
     gene            complement(9317..9913)
                     /locus_tag="A6A29_RS00465"
                     /old_locus_tag="A6A29_00460"
     CDS             complement(9317..9913)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959110.1"
                     /locus_tag="A6A29_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00460"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073717895.1"
                     /transl_table=11
                     /translation="MGVRTRQADARDRDLVVSVLEEAFHHDPVSSWVFPEEEHRRAVHG
                     KFLGVFVDVALAEGRIDLLADGTAVALWLTVPAGVPEEEDPTPALMRRTADPGNERCEL
                     VGRLTGAVHPHDRAHEYLLMVGVSPGRQGEGIGAALIEKVLERCDREGVPAYLEASSAR
                     SRGLYERLGFTFLGRAVELPDGPSLWPMWREPAKG"
     gene            complement(10001..11044)
                     /locus_tag="A6A29_RS00470"
                     /old_locus_tag="A6A29_00465"
     CDS             complement(10001..11044)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959111.1"
                     /locus_tag="A6A29_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00465"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_073718916.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-59, bitscore:
                     196.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDAATEGHEAAALLERTRGIVDPQLRAAVESLPGGIRRVAMY
                     HFGWANADGSPAAGQAGKAIRPALVLAAARALGGDPERAVRAAVAVELAHNFTLLHDDV
                     IDEDTTRRHRPTAWAVFGIPDAVIAGDALLALAQRLLAEDPHPASARASARLSACVIEL
                     CAGQQADCAFEERGPEEVSLDECLAMATAKTGALLGCACALGALYAGAGGRAVGAMDGF
                     GREAGLSFQLIDDLIGIWGDPAHTGKPAGADLAAHKKSLPVVAALTSGTPAAADLAVLY
                     RGAMNTPGEVRRAADAVERAGGRDWAQVCAADRMARAVHHLSRAVPEPAAAGDLLALAE
                     FVTRRTR"
     gene            complement(11139..12545)
                     /locus_tag="A6A29_RS00475"
                     /old_locus_tag="A6A29_00470"
     CDS             complement(11139..12545)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966367.1"
                     /locus_tag="A6A29_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00470"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_073717896.1"
                     /transl_table=11
                     /translation="MSVGEEVRDTQAPPQQSLGTAAARNLATTTKSAPQMQEITSRWLL
                     RMLPWVQVQGGTYRVNRRLSYAVGDGRVTFVQTGDQVSVIPAELGELPPLREFGDEEVL
                     AELSRRCEQRDVAAGEVLAASGEAADRVFLLAHGKVEKVGSGPYGDETVLGVLADGAYF
                     GDRSLVDGEATWEYTARAVTPCTLLTLLRSDVHNLAARSDSLRAHLAGRLSVPQQRTNA
                     HGEAAIDLSAGHVGEPVVPHTFVDYDAAPREYELSVAQTVLKVHSRVADLYSQPMNQTE
                     QQLRLTVEALRERQEHELINNREFGLLNNCDYGQRIQPHDGVPSPDDMDELLSRRRGSK
                     LFLAHPKAIAAFGRECNRRGLLPESVDIGGHQVPAWRGVPIFPSNKIPVTDARTTSIIC
                     MRTGEADQGVIGLQQSGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAVLVPDALGV
                     LENVEVSRWH"
     gene            12723..13169
                     /locus_tag="A6A29_RS00480"
                     /old_locus_tag="A6A29_00475"
     CDS             12723..13169
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="A6A29_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00475"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_073717897.1"
                     /transl_table=11
                     /translation="MRLTRFTDVALRVLMRLAVARDGDPPTTREVAATMRVPYTHTAKV
                     VARLQHLGLVDARRGRGGGLTLTSAGHRASVGALVRELEGADEVVECEGDTPCPLRSGC
                     RLRGALRRAQEAFYATLDPITVTELVSSPTGPLLIGISTGPAPD"
     misc_feature    complement(13292..13310)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            13350..14546
                     /locus_tag="A6A29_RS00485"
                     /old_locus_tag="A6A29_00480"
     CDS             13350..14546
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741535.1"
                     /locus_tag="A6A29_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00480"
                     /product="globin domain-containing protein"
                     /protein_id="WP_073717898.1"
                     /transl_table=11
                     /translation="MLSETSTATVRATLPAVGAAIGDIADLFYRKLFAAHPELLRDLFN
                     RGNQASGAQRQALAGSLAAFATGLVEHPDTRPDVMLSRIAHKHASLGVTAEQYEVVHTH
                     LFAAIADVLGDAVTPEVAAAWDEVYWLMAGALIAVEERLYAQRGVVAGDVWSEWEVAGR
                     IEETADVATFRLRPADGAPAPAFRPGQYVSVQVELPDGARQIRQYSLSRAPGSALRSIT
                     VKRVRGEGSPDGEVSRHLHARTRTGDRLRVSVPYGDLVLDHTDAPLLLASAGIGCTPML
                     SMLEHLVDTGHRSPVTVVHADRSPAAHALRTDHALFTGKLPDAEAHFWYEDPEPGHRAD
                     RTGRVDLTGLVVPSGTHAYLCGPLPFMRAVRGQLLAKGVRAADIHYEVFGPDLWLAAG"
     gene            14681..15271
                     /locus_tag="A6A29_RS00490"
                     /old_locus_tag="A6A29_00485"
     CDS             14681..15271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154135.1"
                     /locus_tag="A6A29_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00485"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_198952962.1"
                     /transl_table=11
                     /translation="MSSPMSASSFLKALKDEGLTVVQVGDWRTHNRDDKGPWGPVHGVM
                     IHHTATRGTDHTVQICRDGHAGLPGPLCHGVTAKDGRVHLVGHGRANHAGLGDDDVLRA
                     VIAEKRLPSDNEANTDGNRHFYGFECENRGDGEDPWPAVQLEAIEKAAAAICRHHRWGA
                     PSVIGHREWQPGKVDPAGFTMDSLRERIHDCLK"
     gene            15372..16286
                     /locus_tag="A6A29_RS00495"
                     /old_locus_tag="A6A29_00490"
     CDS             15372..16286
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142329.1"
                     /locus_tag="A6A29_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00490"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_073717900.1"
                     /sec_met_domain="PALP (E-value: 4.8e-16, bitscore: 55.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHEAHGAAGPRPALPSPLRPAEDERFRRHGVSLLLKRDDLIHPD
                     LPGNKWRKLSLNLAAAAGRTVLTFGGAYSNHLRATAAAGRLLGFPTVGVVRGDELAHRP
                     LNPSLARCAADGMRLHFVDRSTYRAKTDPDVLDGLLRLFGDVDVLPEGGSNALAAQGCT
                     ELGRELRGHTDVAAVACGTGGTLAGLAAGLAPGQRALGIPVLRGGFLGEAVARLQREAF
                     GGPAGQWSLDERFHFGGYARTPPELHAFAEDFEDRHGLPVERMYVAKLLYALTALTGAG
                     AFAPGTTVTAVVTGTPYESSVSR"
     gene            complement(16262..17863)
                     /locus_tag="A6A29_RS00500"
                     /old_locus_tag="A6A29_00495"
     CDS             complement(16262..17863)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510032.1"
                     /locus_tag="A6A29_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00495"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_073717901.1"
                     /transl_table=11
                     /translation="MDALPLVALVAASAAVAGAARRTPVPAPLLLVTAGLVAGYLPGVP
                     SYTLDAHIVLPLLLPPLLYTAAVDSSYLDLRANARPVALLSVGYVLFATFAVGWLAYLM
                     VPDLPLTAALVLGAVIAPPDAVTAAAIARRVGLPARVTTILQGESLVNDATAITAYKVA
                     LAAAVGEGMSWGAGIGEFLLAAFGGVGVGLVLMVPLHWLRTHLKEALLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRSWQVDFATRLQEAAVWKMVAFVLESAVFALIGL
                     QLPFVLKGLGAYGVGEALGYAVAVFLAVVVVRFVWVYPATYLPRWLSRRIREREPGTDW
                     TAPLIVGWAGMRGVVSLAIAFSIPMVMHDGEDFPARNLVLFLTFTTVIGTLVIQGLTLP
                     LLVRVLKLPGRDLQAETLAEAQAQSEASTAAEQRLEELLDDGRNSLPPPLAERLRTVLE
                     RRRNAVWERLGAANPVTGESADDTYRRLAREMIEAEREVFVRLRDERRIDDEMLRTLLR
                     RLDLEEAAAYRETDDS"
     gene            17899..18159
                     /locus_tag="A6A29_RS00505"
                     /old_locus_tag="A6A29_00500"
     CDS             17899..18159
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="A6A29_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00500"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_073717902.1"
                     /transl_table=11
                     /translation="MSECPHVLELPRPEPAPLSGTCLECLAAGSHPVQLRLCLACGHVG
                     CCDSSPLKHASAHFEESGHPVMRSFEQGESWRWCFQDGSIV"
     misc_feature    18283..18297
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    18296..18316
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            18392..18805
                     /locus_tag="A6A29_RS00510"
                     /old_locus_tag="A6A29_00505"
     CDS             18392..18805
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="A6A29_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00505"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_073718917.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDSTVAEDRTVSISLYKQRGAGPGPA"
     gene            18829..19755
                     /locus_tag="A6A29_RS00515"
                     /old_locus_tag="A6A29_00510"
     CDS             18829..19755
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072101.1"
                     /locus_tag="A6A29_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00510"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_073717903.1"
                     /transl_table=11
                     /translation="MRDETIRPGVVRPAGIPEQQARPHPVDGADGSESRTVAVEQSQAE
                     RAVQMSEHGHHDPHDRSGARALFIELRELPDGSAEKAELRNRLVRMHLPLVEHLARRFR
                     NRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPR
                     RLQELRLSLTTATAELSQQHGRSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVPD
                     TDDESPAVADTLGSEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQE
                     VGISQMHVSRLLARTLAQLRERLLVEE"
     gene            complement(19827..20279)
                     /locus_tag="A6A29_RS00520"
                     /old_locus_tag="A6A29_00515"
     CDS             complement(19827..20279)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072100.1"
                     /locus_tag="A6A29_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A29_00515"
                     /product="hypothetical protein"
                     /protein_id="WP_073717904.1"
                     /transl_table=11
                     /translation="MSTQQNTPSSPPPATGEKPGRIAVLAGLNALEGAALVIGGIYMLV
                     MGVLGRPESPQQAETGGVTLIALGLIPLFAARGLLLRRAWSRGPALVTQLMALPVAWTL
                     LRAQGALIPTGIVLAAVAVTGLVLVLNPATSRELGIRRGPRTTPDA"
     misc_feature    complement(20362..20375)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.82"
                     /tool="antismash"
     misc_feature    complement(20931..20946)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.9"
                     /tool="antismash"
ORIGIN
        1 acggcgttga tctcctgact gccggccgac tcgatccgct ccagcggcac ccggacgcgt
       61 ggccagggca gcagcccgga gacggtgagg ccgcgccggt ccacggtgac gcagggccgg
      121 gagaaggtca gcaccagcag gccgaggacc agcagcggga gcgcggcgag ccatccggcg
      181 gcgaacagga ggacgaccgc cgcggcgaac agcgcgaggg tggacagcgg cagccaccag
      241 gagccggtgc tgcgcgccca gcccgcgacc tccccgtcgg cgagcgcgat ccgctcaccg
      301 gtcagcgggt cccggcccgt tcgcgggtcc cgcggcgcgg gggccagccg ggcgatcagc
      361 agcccgagcc caccgccgag ggccccggcc ccgagggccg cggccagctg ccaccacgga
      421 aacccgtcgg tcggggctcc gtcggcgaca tccacgttga cgaacagcac tgcggccagc
      481 agatagccga ggaacgcggc gatggcgtac ccgccggcga cggcccagtc atgggcccgg
      541 tcgtagaacg tgcccttggc caccgtccag gtccacagga cgccgagcac gccgagcacc
      601 agcacggcgt tgacgacgaa ccaggtttgg ccgacatggc cgtcggcatc gccggtggcg
      661 tcgaagtggg ccgccagtcg gtcgggcagc cggtcggcga ggacggcgaa caggatcagg
      721 tcgacgatca gcgcgagcag aaagggaagg gcggcaaggg tgatgcggcc aaggttcttg
      781 cgtgtcatga aaacctccgt tgttcgcatg ttagtagaac aatgcgcgcg cagcaaggtt
      841 tcgtcaagcg ccgggcaagc cttcggcgca ccgggcgggg cacccaccgg tcacggctac
      901 gttcgactcc aagacggggg aaatcgatgt ctgctgtgga gaggcccgtc ggcctcgtac
      961 ccgcccgttc ctgcccgccc gtgcaaccgc tgcggcctac gccgcgcgaa caccgcgatc
     1021 ccggccagtg ggtgacgctc accggctgcc ggaaggtgct gatggtcgtc cacaccgagg
     1081 tgtacgggca gcggctgcgg gatctgctgc cgctcgtgga atccgacctg cggatccagg
     1141 tggctttcac catcgcgccg cacgcgttca acgggggcgc cgtccgttcg ctgccggccg
     1201 aggggaccac cgtgatcccc tgggaggagg cggtccggac cgagttcgat ctcgcgctcg
     1261 ccgcaggctc acagggcatg gagcaggtgc gcgccccgct gatccggatg ccccacggca
     1321 tcggccacat gaagctgtcg cgggcggccg acggcccgga aggggcgccc cggaccgtcg
     1381 gcggcctggg caggaagtac ctgatgcggg acggcagggt ggtcccgagg tccatcgtcc
     1441 tggcgcaccg cgaggatctc gcggagctgg ggaggtggtg cccggaggcg ctgccggcgg
     1501 cggaggtggt cggggacgcc agccacgacc gcttggcggc cagtctgccg ctgcgggagc
     1561 actaccgcag ggcgatgggg ctgaagccgg gacagcggct cctgctggtc tcctccacct
     1621 gggggaccgg ctcctcgttc aaccggctgg acgccctgct gccccggctg ctggccgaac
     1681 tgccgcgcga cgcgtaccgg atcgcgctgc tcgtccaccc caacgtctgg tccgggcacg
     1741 gccgttggca ggtgcacgcg tggctggagg cgttccggcg gcgcgggatc gcgatcgtgc
     1801 cgccggaagc ggactggcgt gccgcgctga tcgcctccga ctggctcatc ggcgaccacg
     1861 gctccgtgac gctgtacgcc accatgaccc gggcgcgcat cctgctggcc cggttccccg
     1921 aggcggacgt caacccgctg tcgccggggg cggaactggc caggaccgcc ccggcgctct
     1981 cccccgcgca tccgatcacc gagcaactcg cctacgcgga cgccgagtac ccggccgcgg
     2041 agtacgcacg gatcgccgcc cggatctcgt ccgagcccgg acagttcaat cagcggatgc
     2101 gcggggtgct gtaccgcatg ctcggcctcg gccagcccgc cttcgccccg gccacccggc
     2161 cgctgccgct ccccgcaccg ctggatcccg ccccttcggc ggacccctgg ggagccgacg
     2221 gaacggagat ctccgcatga acggcgacac caccgcgaac ggcggcgagg acggcaggcc
     2281 cctgtgcgtc gacctcgacg gtccggccgg cgagagctgg cggcagtgcg ccgacgtcct
     2341 gcacggcggc cggccccgtc cggcccgtga ggccgcacgg gtcgcccggc aggcgctggt
     2401 gcgctacccc ggctgtctgc tgaccgtcgt gagccgcacc gacggcggct gcacgacggc
     2461 ctcctggctc gacggccggc cgagcgtgcg ggtgtacgcg cccggccgcg tacgtccggg
     2521 acggggcacc acccggctcg tcgccgagct gtacgcgaag ctgatcgacg aggccgcgcc
     2581 gcgcccggac ccggcggtcg ctccggggca gggcttccgt acggccccgg cgtgttccgg
     2641 tgaccgtgtc agcgggccgc tcctcccagg cggtcctgaa gacgccggac atcatccgcg
     2701 ctgacggatg cgtaacgggc cagggactgc tcgtaccagc ccctggcctc cgcgccctcc
     2761 ccgcgctcgg ccgccgtctc cccgagcatc tccagcaccc ggccctgcca gtgcacggag
     2821 cccgtcgcct cgaactcgcc cagcgccatg gccagttccc cggcggcgag cgcgaagtcg
     2881 cccacccccg cgtgggcgcg ggccaggtgg gcgagtgcgc gggcggcgtc gtacgcgtcc
     2941 cgcacatcga ggagtacggc gcgggcgcgc gacaggtggc cgagcgcccg ctcggggcgg
     3001 ccctccgcca actccacgtc accgaggcac agttcggtca gggcgacgcc ccgccggtag
     3061 ccggccgcct cgcgcagtgc gagggcccgg acgaagaagg accgggcttc ggtgagccgc
     3121 ccggcgagcc ggtgggactg gcccgcaccg tgcagggcct gggcctcggc gacggagtcc
     3181 tgatcacgca gggcggcctc ggcggcccgc gtgaaccagg cgacggcttc gtcgtgacgg
     3241 cccacgttgc gcagcccggt cccgccggag gtgagcatcc ggctctcccc ctgcggatca
     3301 ccggcccgtc gggcggccgc cagacccgct tcgtgcgcct cgatccagag gtcgtacggg
     3361 cgcagccgga ggaagagcgg ccacatggcg tcggcgagct gccacaccgc ggcgtcccat
     3421 ccgaggtcgg cagctctccg taacaccgcc atcagatggg tccgttccgc gtccagccac
     3481 tccagcgcac cggtcgcgtc gtcgaagggc gtcggctgct cccggtcaca ggcgtagtcc
     3541 ctgcgcaggg tgcggtggct gggcgacagc agggcctcgg cggccgtggc ggtgcgcaga
     3601 tacaggtcca cgacgcggcg taccgtccgc cgccggtcct cggggctctc gtccgcctcg
     3661 gcgagtgccc cggcgtgcgc gcggacgagg tcgtggaacc ggaagcggtc caatcccgtg
     3721 acggggtccg ggccgaggtc ctccagcaga ttcacctcgg ccagcgcgtc gacgatccgg
     3781 tccgcctcca gcgggtcggc cccgcacgcc gcggcggcga cccggacgct gaacacggac
     3841 accggcagga ttcccaaccg ccggtacccc agggcgagat cgggcttcag aagccggtac
     3901 gaggcgtcca gcgcggcccg caccgcgggc tccccctcga ccttgagggt gtccaggccg
     3961 ccgtccccgc ccagggcgag cgccatcgcg gcgagcggct gccgggggcg tacggccatc
     4021 cgggccgccg cgatgcacac cgccagcgga agacccgcgc acagtgccgc cacctcacgg
     4081 gccgcctcgg gttcacggcc gacccggtcg gaaccgattc tgcggctcaa cagttccacg
     4141 gtgtcctcgg tgtccagcac ccccagctgc tggaagaccg cgccgtccac cgccagtccg
     4201 gcgagccgga acctgctggt gacggcgacg aggctgccct cggtgcccgg cagcagggga
     4261 cgcacctggc ccgcgctcac cgcgttgtcc agcatcacgg cgatccggcg gcccgcggta
     4321 cgggtacgcc acagggcggc cagttcgccg agcccctgcg gtacctgcgt gaggcccagg
     4381 gcccgcagga actgcgcgag tatctccgcg ggcggggcgg ggctgcccgt cgcggagtgg
     4441 ccgcgcaggt ccgcgtagaa ctgcccgtcg gggaactgtt cgcccatgcc gcgcagccag
     4501 ctggacgcga gcgcggtctt ccccaccccg gcgggtccgc tgatcaccgc gagcacgggc
     4561 gcggacggta atcggcccgc catctcgcgc agcgaaccga gttcgctctc gcggccgagg
     4621 aagtacggcg gcgcgggcag cagttgacgt gccgtcgcga cggccggctc gggcgcggag
     4681 tggaagtgga ctccgccgtg gatgccgtgg gcctggacga cgggaccgct gagggtggcg
     4741 tcgccgctga cggtgttgtc ctgaatattc ggaccgcgaa caccgccccg gcctccatcc
     4801 gccgtgtggc cggaccccgg tactggttcc atatctgccg ccttcccccg tatgcgccac
     4861 catgtacgtg cccgcggtct ctccggtcgg cccgtggttt acccctttct tcgtccgcac
     4921 agaccaaaag cccttacacg ttgaacattt gagccaagat aatcgatcat tcgatgccat
     4981 cttttgatca aagttggcat cgtgtcatcc tttcttgctt gggtatgcgc ctcgacacgg
     5041 acgtcagcgg tgggtcgtgg cgacgacgga ctgccgtggc cgcagaccgg cgcacggcgg
     5101 cacgagcgga acagccgggc cgagcgcgga ccggcgatgg gggcgctggt ggaattcgag
     5161 atccgcatcc tggggtcgat cgagctacgc gtggacgggc ggagggatcc actcggcacg
     5221 gccaaggaga gagcgatgat cgccgcgctc gccgtcgacg ccggccgccc ggtcgctctg
     5281 gactccctgg tccaccggtt gtgggacgac gccccgcccg cgaaaccccg ggcgagcctg
     5341 catgtgtacg cggcgagaat ccgccgcagg ctgggcgaac gggcgggcgg gccgacccgt
     5401 atcgtccagc aggcccacac gtactccctc gtcgtcgatc ccgacagcgt ggacagtcat
     5461 cgcttccagc gcctgaccgc cgaggcgctc gcccggtccg acgacggtga cgggcccagg
     5521 gccctggccc tcctgcgcga ggccgacagc ctgtggcggg gcgatccgct cacggggatg
     5581 cccggcctct gggccgagag cgtcaggacg aacctgctcg aaaagcgcct cgccgcgacg
     5641 ctggcccgcg tcggcatcga actgcgcacc ggacggtacg cggagctcgt gcccgacctc
     5701 tccaccctct tcgagctgca ccccacggac gagaccctgg ccggccacct catggtcgcg
     5761 aactacggct gcggccggca ggccgacgcg ctgcgcacgt tcgacaccgt ccggcgccgg
     5821 ctcggtgagg agttcggatc ggatccgggc gaggcgctga ccaggctcta ccagctcatc
     5881 ctgaaccggg taccggtctc cgggctcctg agcggccccg aaccggtgac cacggccccg
     5941 cacaccctgc ccagccacgg cgacctcgtg ggcagggacc gggagatgct caccctcctc
     6001 gcccgtccgc cggcgggctc ggtgatcgca ctccagacca tcagcggcat gggaggcgtg
     6061 ggcaagacgc tcctggcgct ccacgccgcc cgcgcactcg ccccgcacta cccggacgga
     6121 cagctccatc tcgatctgag cgcacacacc gcggacggac acccgctgag ccccgagtcc
     6181 gcgctcaccc ggctgctgag ggacttcggg gtgcccgtca cggatctgcc ggacgacctg
     6241 gaggggctgg tgtccctctg gcgcaccctg ctcagcaccc gtcgctcggt gatcgtcctc
     6301 gacgacgcgg cggacgccga gcaggtggcc ccgctccttc cgggcacctc cgagtccctg
     6361 ctcatcatca ccagccgtcg acggctcacg gggctgccgg gcatccgctc gctcttcctg
     6421 gacgtcctgc cggccgacga cgcgagcacg ctgttccgca ggctggtggg cccggagcgg
     6481 acctccgacc tcgacgaggt ggcggacatc gtgcggctgt gcggccacct tccgctcgcc
     6541 gtggagatcg ccgcgggcag gctgggctca cgcccctcct ggaccacttc ccacttgatc
     6601 gaaaaactgt cgcgcgaaca cggacgcctc aatgaaatcc gggacggcta tcgaaagatc
     6661 gccggagtgt tcgagatgtc ctaccacaca ctcgggaccg aagagcgaac gatctttcga
     6721 cagttgagcc tgcattttgg gccggatttc accccccact ccgccgccgc gctcaccggg
     6781 cttccgctgg aggagacgga acgcgtcctg gattccctgc tggacgccca tctcctccag
     6841 gaaccggccc cggaacgctt tcgcttccat gatcttgtgg gtgagtgcgc acggagcctg
     6901 agcgcgacgg aggaccgata cgaaggtcaa cttcccgccg tacgaaggat gatcgatttc
     6961 tatgtccacg gcgccgagaa ggccgaccgg ctgatctatc cgcggcgcct gaaagtagat
     7021 atcgaggagg ccgcgacgga gttcgccctg cccgaatggc aggacgcctc ggccgcccgg
     7081 cactggctcg tgcaggagca cggcgccctc gtcgcggcgg agcaccgtgc ccgcggcaac
     7141 ggactcaccc gccaggccgc ccgcctggcc cacgcgctcg cggcccatct ggacgaggag
     7201 ggctactggg gcgaggcacg gccgatgcac acggccgccg ccgagttctg gcacgagagc
     7261 ggcgaacgcc gcccggaggc cctcgcgctg atcgatctgg ggacgacgct ggcacgggcc
     7321 ggccgctacg aggccgctct cgccgccggt catgcggcca tgcgggcggc gggcacgctg
     7381 gacgatccgg cgacggacgc cgaagcgcgt catctgctcg gcgtcattca ctggcatatg
     7441 ggacagctcg acgaagccct ttccttccag aatcagaccc tggaacgtcg gctcaggtcg
     7501 ggtgacatat ggcagctcgc acggacaaga aataacctcg gtatcaccca cctctttctc
     7561 ggaaaccaca cgacatcaat ggaattcttt gtctccgccc tgggcggatt ccgtcggtcg
     7621 ggtgatgcgc gggaagaatt caatgtgctg aataatctct cggaccttca cttccagacc
     7681 ggcgaccgtg aatccgcgcg acgactcctc aagaaatccc tgtcgaatcc ccggctggcc
     7741 ggaacgcctt tggcccgcgc cacggggcag gtaaatctgg cgaacaccat ggaaatgccg
     7801 gaggaagtgg aagcggcgct ggatctctat cgcgaggcgc tgctgtcgtt ccggcagctc
     7861 ggcgaccggc gcaacgcgtc catcaccctg caccggatgg gcgtcgcgtt cgaggagtcc
     7921 ggcaacgacg accaggcggt cgcccaccat gagcgcgccc ttgacctggc caccggcatc
     7981 ggcgcgggcc atgagcgcat gctcgcgctc cggggcatgg ccgcggcgga acggcggctg
     8041 ggccgcacgc aatcggccgc gcgacatctc gcggaggcgc tcaccctggc ccagcacatc
     8101 ggcgccatgg acgaagcggc gcggacgcag gcggaattcg ccgctctcca agaagaatcc
     8161 gagggcgccg gaacagagtg acaggacccc ggcgggaaaa caacgaaatt accgcccgac
     8221 ttgttcaccc gaaggcagac ggagagtatg agccctcggc acgaacgctg ccgaagaaac
     8281 tccctgaacg cctggagaaa agcgcaccat gttcaagaag tcagcaatta tccccgtggc
     8341 atatgccatt gcgggtgcca ccctcgtcgc cctgatctgc ctgccgtcga tgtccgcacc
     8401 gaggaacgtc acgcatatga cgaccgtcag ctgatcccct gacgacggcg accgtcacgc
     8461 cggtgcgccg ataaaggcgc ccggcggcga aacacaccga agcggacctg agccgcaaaa
     8521 ggcgcgcccc gtaccggaat atgcaattcc agtacggggc gtgacggcgg gcgggcacgg
     8581 ggcgagacgg tcaggcgagt tccagcggga acgcgccccg gtggccggtc ccggcgcctt
     8641 cggccgggcg cgcctcgaac tcgcggcagc tccagatctc ctgcacgaac ccgctccgcc
     8701 ggtcccacag gtccaggacg tcgtcctcgc ccgccgctcc ccggtacgcg tctttcgcac
     8761 cgcggaagca ggcgagagcg ccggagaggc cccggcccgg ggccgggaag tagtcggaga
     8821 aggcgcaggc gatacacgtc tgcacctgtg tgccggacgg caggatgcgc tggatcgtgg
     8881 ccatcgcggc ggcgaagtcg cgttcggcgc gggcggattc atagaccgcg ccgtccaggt
     8941 gcagggcgag gtagaggtcc ggatcgctgc gccgcagcga cagcaggcaa ctgagcgtgg
     9001 cctggcggac cgtgcccgcg gagcggaccg gaagcgggag gtcccactcc agtacgcagt
     9061 cggtgagcgc gccgtccgcc agggcgaaca tgccgctttc gggcggtatc ccgcccaccg
     9121 gaacgaggtc gtcgaagctc tcgccctcga agtcgactcc cctgatccgg atccggagtt
     9181 gctgtccgtc cgtggtgaga acgacggcat cggaaccctc gcggtcccgg taccagcctg
     9241 cccacgactc atctgtcatg agcagggact gtagcccgtg cccggcgcgg tccccgtggc
     9301 gccctccacc tgcgcatcag ccctttgccg gttcgcgcca catgggccac agggacggtc
     9361 cgtcggggag ctcgacggcg cggcccagga aggtgaagcc gagccgctcg tagaggccgc
     9421 ggctgcgggc actgctcgcc tccagatagg ccgggacgcc ctcgcggtcg catcgctcca
     9481 ggaccttttc gatcagcgcc gccccgatgc cctccccctg gcgtccgggg gagacaccga
     9541 ccatgagcag atactcgtgg gcccggtcgt gcggatggac ggcaccggtc agccggccca
     9601 ccagttcgca ccgttcgttg ccggggtccg cggtccgccg catcagcgcg ggggtggggt
     9661 cctcctcctc gggcaccccg gccggcaccg tgagccacag ggccacggcg gtgccgtccg
     9721 ccagcaggtc gatacggcct tcggcgaggg cgacatcgac gaagacgccg aggaacttcc
     9781 cgtgcaccgc gcgccggtgc tcctcctcgg ggaagaccca gctgctgacc gggtcgtggt
     9841 ggaacgcctc ctccaggacc gatacgacca ggtccctgtc ccgcgcgtcc gcctgccgtg
     9901 tccgtacacc catgaccggc tcccgcccct tcttcctccc gacctcaacc gacgggtgga
     9961 atcctagagt tggggccggg agcgggtcac aggaggtcgg tcagcgggta cggcgcgtga
    10021 cgaattcggc cagcgccagc aggtcccccg ccgcggccgg ctcgggcacc gcgcgggaca
    10081 gatggtgcac cgcgcgggcc atccggtccg ccgcgcagac ctgtgcccag tcccggccac
    10141 cggcccgttc gacggcgtcg gcggcccgcc tcacctcccc gggcgtgttc atggcgcccc
    10201 ggtagagcac cgccaggtcg gcggcggcag gggtgcccga ggtgagcgcg gccaccaccg
    10261 gcagggactt cttgtgggcg gccagatccg ccccggccgg cttgcccgtg tgtgccgggt
    10321 ccccccagat gccgatcaga tcgtcgatga gctggaacga gagtcccgcc tcacgtccga
    10381 agccgtccat cgcgccgacg gcccggcctc cggccccggc gtacagggcg ccgagcgcgc
    10441 acgcgcagcc gagcagggca ccggtcttgg cggtcgccat cgcgaggcac tcgtccagcg
    10501 agacctcttc ggggccgcgc tcctcgaagg cgcagtcggc ctgctgcccc gcgcacagct
    10561 cgatcacgca ggccgagagc cgcgcggagg cgcgggcgga ggccgggtgc gggtcctcgg
    10621 ccagcagccg ctgggcgagg gcgagcaggg cgtcgcccgc gatcacggcg tccgggatgc
    10681 cgaagaccgc ccaggccgtc ggccggtgcc ggcgggtggt gtcctcgtcg atgacgtcgt
    10741 cgtggagcag cgtgaagttg tgcgccagct ccacggcgac ggcggcgcgg acggcccgct
    10801 ccgggtcacc gcccagggct cgcgcggcgg ccagcaccag cgcgggcctg atggccttgc
    10861 ccgcctggcc cgcggccgga ctgccgtccg cgttcgccca gccgaagtgg tacatcgcga
    10921 cgcggcggat tccgccgggc agcgactcca cggccgcgcg cagttgcgga tcgacgatgc
    10981 cgcgcgtgcg ctccagcagc gcggcggcct cgtgcccctc cgtcgctgcg tccgtactcg
    11041 tcatggtcac gggtctctcc cctgggtggt gcggtgggta cgggcggggc ggtgggcccg
    11101 gacggcgctg gccggccggg cccaccgggg gaaaggggtc agtgccagcg gctcacctcg
    11161 acgttctcca gtacaccgag ggcgtccggg accagaacgg cggcggagta gtaggcggtc
    11221 acgaggtagg agatgatcgc ctgctcgtcg atgcccatga agcggaccga caggctcggc
    11281 tcgatctcgt ccgggatgcc gctctgctgg agcccgatga cgccctggtc ggcctcgccg
    11341 gtcctcatgc agatgatcga cgtggtgcgg gcgtcggtga ccgggatctt gttggacggg
    11401 aagatcggca ccccgcgcca ggccggcacc tggtggccgc cgatgtccac gctctccggc
    11461 agcagaccgc gcctgttgca ctcgcggccg aaggcggcga tggccttcgg gtgggcgagg
    11521 aagagcttcg atccccgcct gcgcgacagc agttcgtcca tgtcgtcggg gctgggcacc
    11581 ccgtcgtgcg gctggatccg ctgcccgtag tcgcagttgt tgagcagtcc gaactcgcgg
    11641 ttgttgatca gctcgtgctc ctggcgctcg cgcagcgcct cgaccgtgag ccgcaactgc
    11701 tgctcggtct ggttcatcgg ctggctgtag agatcggcga cccggctgtg caccttcagc
    11761 acggtctggg ccacgctcag ttcgtactcg cgcggcgccg cgtcgtagtc gacgaaggtg
    11821 tgcgggacga ccggttcgcc cacatggccg gcggagaggt cgatcgccgc ctcgccgtgg
    11881 gcgttggtcc gctgttgcgg gacggagagc cggccggcga gatgggcccg gagcgagtcg
    11941 gaccgggccg cgaggttgtg cacgtccgaa cggagcagcg tcaggagcgt gcagggggtg
    12001 acggcgcggg cggtgtactc ccaggtggct tcaccgtcga ccaggctccg gtcgccgaag
    12061 tacgcgccgt cggcgaggac accgagcacc gtctcgtccc cgtacggccc ggagccgact
    12121 ttctccacct tgccgtgcgc cagcaggaag acccggtccg ccgcctcccc cgaggcggcg
    12181 agcacctccc cggcggccac gtcccgctgt tcgcacctgc gggagagttc ggcgaggacc
    12241 tcctcgtcgc cgaactcccg caagggcggc agctccccga gctcggcggg gatgacggag
    12301 acctggtcgc cggtctgcac gaaggtcacc cggccgtcgc cgaccgcata gctgagccga
    12361 cggttcaccc ggtacgtacc gccctgtacc tgcacccacg gcagcatgcg cagcagccac
    12421 cgggaggtga tctcctgcat ctgcggcgcg gacttggtgg tcgtcgcgag gttccgcgca
    12481 gccgccgtgc ccagactctg ctgcggcgga gcctgcgtgt cgcgaacctc ttcaccaacg
    12541 gacatctgac gtcctttcga tcatgggctg acctgcgtgc agaagccttt cagcacggtg
    12601 agttgcttcg ccattacaca aacgagtgtg attaaccggg ctccggacgg ggcacgttgc
    12661 tcacgtcgcc cggcgcactc cttaatttgc atcatccatg ccacttatct agcctgagcg
    12721 tcatgcggct gacgagattc accgatgtgg cactgcgcgt gctcatgcga ctggcggtcg
    12781 cgcgggacgg ggatccgccg accacccggg aggtggcggc caccatgcgc gtgccgtaca
    12841 cccacaccgc caaggtcgtc gcccgcctcc agcatctcgg cctggtcgac gcgcgccgcg
    12901 ggcgcggcgg cggactcacc ctcacctcgg ccggtcaccg cgcctcggtc ggcgcgctcg
    12961 tacgggaact ggagggtgcg gacgaggtgg tcgagtgcga gggcgacacc ccgtgcccac
    13021 tgcgctccgg ctgtcggctg cgcggtgcgc tgcgccgggc gcaggaagcg ttctacgcca
    13081 cgctcgaccc gatcaccgtc accgaactcg tctcctcccc caccggaccg ctgctgatcg
    13141 gcatcagcac gggccccgca ccggactgac ccaccggggc gaccggtacc gcgagcaccg
    13201 gcaccccgag ccgcgccgcg ccgcgaccag tgctccaccc cgcgttccgc cccgccgacc
    13261 gccccacccc ggctcacccc ggccgaaaat gcgcattctc gataccaatt aattacgccg
    13321 tcctccacct caccccgagg agtccaccca tgctctccga gacctcgaca gccaccgtcc
    13381 gcgccaccct ccccgccgtc ggcgccgcca tcggggacat cgcggacctc ttctaccgca
    13441 agctcttcgc ggcccacccc gaactgctcc gcgatctctt caaccgcggc aaccaggcgt
    13501 ccggcgccca gcgccaggcc ctcgccggtt ccctcgccgc cttcgcgacc gggctcgtcg
    13561 agcacccgga cacccgcccc gacgtgatgc tgagccgcat cgcccacaag cacgcctcgc
    13621 tcggggtgac cgccgagcag tacgaggtgg tgcacaccca cctgttcgcc gccatcgccg
    13681 acgtactggg cgacgccgtc accccggagg tcgccgccgc ctgggacgag gtctactggc
    13741 tgatggcggg cgcgctgatc gccgtcgagg aacgcctgta cgcgcagcgg ggcgtcgtcg
    13801 ccggagatgt ctggagcgag tgggaggtgg ccggccgcat cgaggagacc gcggacgtcg
    13861 cgaccttccg gctgcgcccg gcggacgggg cacccgcccc cgccttccgg cccggccagt
    13921 acgtctccgt acaggtggaa ctgcccgacg gggcccggca gatacgccag tacagccttt
    13981 cccgcgcgcc ggggtcggcg ctgcgctcga tcaccgtcaa gcgggtgcgg ggcgaggggt
    14041 ccccggacgg cgaggtctcc cgtcacctgc acgcccgcac ccggaccggc gaccggctgc
    14101 gcgtctccgt cccctacggg gacctggtgc tcgaccacac ggacgccccg ctgctgctcg
    14161 cctccgcggg catcggctgc accccgatgc tgtcgatgct ggagcacctg gtggacaccg
    14221 gccaccgctc cccggtcacc gtcgtgcacg ccgaccgctc gcccgccgcg cacgccctgc
    14281 gcaccgacca cgcgctgttc accggcaaac tcccggacgc cgaagcgcac ttctggtacg
    14341 aggacccgga gcccggccac cgggccgacc gcaccggccg ggtcgatctg accggcctcg
    14401 tcgtcccgtc cggaacgcac gcctacctct gcggaccgct ccccttcatg cgcgccgtcc
    14461 gcggccagtt gctggccaag ggggtccggg cggcagacat ccactacgag gtcttcgggc
    14521 cggacctctg gctcgccgcc ggctgacacg gcgccccctg aagctgctca cgggcgtgtc
    14581 cggatcggct cgcacaccgt acgaacaaat agcccagaag gctgcgttcc ggtacaagcg
    14641 gtgtacggac acactccccc acgcaccaaa ggagtcggcc atgtcctcac ccatgtccgc
    14701 gagcagcttc ctcaaggccc tcaaggacga aggtctcacc gtcgtccagg tcggcgactg
    14761 gcgtacgcac aaccgcgacg acaaggggcc ctgggggccg gtgcacggcg tgatgatcca
    14821 ccacaccgcg accaggggca ccgaccacac cgtccagatc tgccgtgacg gccacgcggg
    14881 ccttcccggc cccctgtgcc acggcgtcac cgccaaggac ggccgcgtcc atctcgtcgg
    14941 ccacggccgc gccaaccacg ccgggctcgg cgacgacgac gtcctgcgcg ccgtcatcgc
    15001 cgagaagcgg ctcccctcgg acaacgaggc caacaccgac ggaaaccggc acttctacgg
    15061 cttcgagtgc gagaaccgcg gcgacgggga agacccctgg cccgccgtgc agctcgaagc
    15121 gatcgagaag gctgccgcgg cgatctgccg ccaccaccgc tggggagcgc cctcggtcat
    15181 cggtcaccgg gagtggcagc cgggcaaggt cgacccggcg ggcttcacca tggactccct
    15241 gcgcgagcgg atccacgact gtctgaagtg acggcccccg cccgcccgcc ggaaacgccc
    15301 acccgccggg gacgcacgca cgcccggggt cacggggcag ccctcgtcgg ccgccccgtg
    15361 acaatggacg tatgcaccac gaagcgcacg gcgccgccgg gccgcggccc gccctcccct
    15421 cgccgctgcg ccccgccgag gacgagcgct tccggcggca cggcgtgagc ctgctgctca
    15481 agcgcgacga cctgatccac ccggacctgc cgggcaacaa atggcgcaag ctctccctca
    15541 acctggcggc cgccgccggc cggaccgtgc tgaccttcgg cggcgcctac tccaaccatc
    15601 tgcgggccac cgccgccgcc gggcggctcc tcggtttccc cacggtcggt gtcgtccgcg
    15661 gcgacgagct ggcgcaccgc ccgctcaacc cgtcgctcgc ccggtgcgcg gccgacggca
    15721 tgcgtctgca cttcgtggac cgctcgacgt accgcgcgaa gaccgatcct gacgtcctgg
    15781 acgggctgct gaggctcttc ggggacgtgg acgtcctccc ggagggcggc agcaacgcgc
    15841 tggccgcaca gggctgcaca gagctcgggc gcgagttgcg cgggcacacc gatgtggcgg
    15901 ccgtggcctg cggtaccggc ggcaccctgg ccggcctcgc cgcgggcctg gcccccggcc
    15961 agcgcgccct gggcatcccg gtcctgcgcg gcggcttcct gggcgaggcg gtggcccggc
    16021 tgcagcgcga ggcgttcggc ggcccggccg gacagtggtc cctggacgag cgcttccact
    16081 tcggcggcta cgcccgtacg cccccggagc tgcacgcctt cgccgaggac ttcgaggacc
    16141 ggcacgggct gcccgtcgag cggatgtacg tcgccaagct gctgtacgcg ctgacggcgc
    16201 tgaccggggc gggcgccttc gctccgggaa cgacggtgac cgccgtggtg acgggcaccc
    16261 cctacgagtc gtccgtctcc cggtaggccg ccgcctcctc caggtcgagg cgccgcagca
    16321 gggtccgcag catctcgtcg tcgatccgcc gctcgtcccg cagccgcacg aagacctccc
    16381 gctcggcctc gatcatttcc cgggcgaggc gccgataggt gtcgtccgcc gattccccgg
    16441 tgaccgggtt ggccgcgccg agccgctccc acacggcgtt gcggcgccgt tccagaacgg
    16501 tgcgcagccg ctcggcgagg ggcggcggca ggctgttgcg cccgtcgtcc agcagttcct
    16561 ccaggcgctg ttccgcggcc gtggacgcct cgctctgcgc ctgcgcctcg gccagcgtct
    16621 ccgcctggag atcacgcccc gggagcttca gcacccgtac caggagcggc agggtgaggc
    16681 cctggatcac cagcgtgccg atgaccgtgg tgaaggtcag gaacagcacc aggttccggg
    16741 ccgggaagtc ctccccgtca tgcatgacca tcgggatgga gaacgcgatg gcgagcgaga
    16801 cgaccccgcg catcccggcc catccgacga tcagcggcgc ggtccagtcg gtcccgggtt
    16861 cacgttcccg gatgcgccgg gagagccacc ggggcagata ggtggccgga tagacccaga
    16921 cgaagcgcac cacgacgacc gcgaggaaca ccgccaccgc gtagccgagc gcctccccga
    16981 ccccgtacgc gccgagcccc ttcagtacga agggcagctg gagcccgatg agggcgaaca
    17041 cggcggactc caggacgaag gcgaccatct tccagaccgc cgcctcctgg agccgggtcg
    17101 cgaagtcgac ctgccacgag cggtgcccca ggtagagcgc gacgacgacc accgcgagga
    17161 cgccggaggc atgcacccgt tcggccgccg cgtacgccac gaaggggatc aggagggaca
    17221 gcgtgttctg gaggagtgcc tccttgaggt gggtgcgcag ccagtgcagc ggcaccatca
    17281 gcaccagacc cacgcccacc ccgccgaacg ccgccagcag gaactcaccg atcccggcgc
    17341 cccagctcat cccctcaccg accgccgcgg ccagcgccac cttgtaggcg gtgatggcgg
    17401 tggcgtcgtt caccagggac tcgccctgga ggatcgtggt gacccgggcg ggcagcccca
    17461 cccggcgggc gatggcggcg gccgtcacgg cgtccggcgg ggcgatcacc gccccgagga
    17521 ccagcgccgc cgtcagcggc aggtcgggca ccatcagata ggccagccag cccaccgcga
    17581 acgtcgcgaa gagcacgtac cccacggaga gcagggcgac cggcctcgcg ttggcccgca
    17641 gatcgaggta cgagctgtcg accgccgccg tgtagagcag cggcggcagc agcagcggga
    17701 gcacgatgtg cgcgtccagg gtgtacgacg gcacccccgg cagatacccg gccaccagcc
    17761 ctgcggtgac cagcagcagc ggggcgggca cgggcgtccg gcgcgccgcc cccgcgaccg
    17821 ccgcactggc cgcgaccagg gcaaccagcg gcaatgcgtc catctcacgg tcctcacatc
    17881 cgtcgtaacc tggcaatcat gagtgagtgc ccgcatgttc tcgaactgcc gcgccccgag
    17941 ccggccccgc tcagcggcac ctgcctcgaa tgcctggccg cgggcagcca ccccgtacag
    18001 ctgcgcctgt gcctggcctg cgggcatgtc ggctgctgcg actcgtcgcc actgaagcac
    18061 gcctccgcgc acttcgagga gtccggtcac ccggtgatgc ggagcttcga gcagggcgag
    18121 agctggcgct ggtgcttcca ggacggttcg atcgtctgac gtctgggtac gtcaatccgg
    18181 cgccggttct tcgcaattgg ccgctgcaga cctctagcca ctgtgtgtac tcatgggctt
    18241 accatgagtg acgagtagag gatggggtcc tggcgacacg gcatcatggt tcgcgatagc
    18301 gtcgccgagc caagaaccga cgacggaccg catggctccg ggccacttct cccggaacct
    18361 cgaaagagtt tgtgccacct tggaggtgag ggtgtcccag atcgcaggcg agcccgggaa
    18421 tcaggacttc gtagaggtcc ggctgcccgc tgcgggtgcc tacctgtcgg tgctgcgaac
    18481 ggccacggcc ggtctcgcag cgcgtttgga cttcactctc gacgagatcg aggatcttcg
    18541 catcgcggtc gacgaggcct gcgcgatcct gcttcagcag gccgtgccgg gttccgtcct
    18601 cagctgtgtg ttccgtctcg tcgacgactc tcttgaggtg acggtgtcgg cccccacgac
    18661 ggacggccgc gcgcccgagc gtgacacctt cgcctggacg gtgctctccg cactggccgg
    18721 aaaggtcgac tccacggtcg ccgaagaccg tacggtcagc atcagcctct acaagcaacg
    18781 cggcgcgggc cccgggccgg cgtgagcgac gggaacgggg acggtcctgt gcgggacgag
    18841 acgatccgac ccggggtggt gcgcccagca ggcatcccgg agcaacaggc ccggccgcat
    18901 ccggtggacg gagcggacgg gtccgagagc cgtacggtcg cggtggagca gtcgcaggca
    18961 gagcgggcgg tccagatgag cgagcacggg caccacgatc cacacgaccg cagcggggcg
    19021 cgggccctgt tcatcgagct gcgggagctg cccgacggct cggccgagaa ggcggagctg
    19081 cgcaatcggc tggtccggat gcatctgccg ctcgtggagc atctggcccg ccgcttccgc
    19141 aaccggggcg agccgctgga cgacctgacc caggtcgcca cgatcgggct catcaagtcg
    19201 gtggaccggt tcgacccgga ccgtggcgtg gagttctcga cgtacgcgac tcccaccgtc
    19261 gtcggcgaga tcaagcgcca cttccgcgac aagggctggg cggtgcgggt gccgcgccgc
    19321 ctccaggagc tgcggctctc gctgaccacg gcgaccgcgg agctctccca gcagcacggc
    19381 cgctcaccga ccgtgcacga gctggcggag cgcctgggca tctccgagga agaggtgctg
    19441 gagggtctgg aatcggccaa cgcctacagc accctgtcgc tggacgtccc ggacacggac
    19501 gacgagtcgc ccgcggtcgc ggacaccctg ggctccgagg acgaggcgct ggagggcgtc
    19561 gagtaccggg agtcgctgaa gccgctgctg gaggacctgc cgccgcgcga gaagcgcatt
    19621 ctgctgctgc gcttcttcgg gaacatgacc cagtcgcaga tcgcgcagga ggtcggcatc
    19681 tcgcagatgc atgtctcgcg gctgctggcc cgcacgctcg cccagttgcg cgagcgcctg
    19741 ctcgtggagg agtagggccg acagcgaaga ccgcccggaa cgggccgccg gagcggtggc
    19801 gaacgcggcc tgtcggtcgt ggtgggtcag gcgtcggggg tcgtacgcgg cccccggcgg
    19861 atgcccagct cccggctggt cgccgggttc agcacgagca cgagaccggt cacggcgacc
    19921 gcggccagga cgatcccggt ggggatcagc gcaccctggg cccgcagcag cgtccaggcc
    19981 accggcagcg ccatgagctg tgtgacgagc gcgggccccc ggctccaggc gcgccgcagc
    20041 agcagcccgc gggcggcgaa cagcggaatc aggccgagcg cgatgagggt gaccccgccg
    20101 gtctccgcct gctgggggct ctcgggccgg ccgagcaccc ccatgaccag catgtagatc
    20161 ccgccgatga cgagtgccgc cccttcgagg gcgttgagtc cggcgaggac ggcgatcctg
    20221 cccggcttct ccccggtggc cggagggggc gaagagggcg tgttctgctg agtactcacg
    20281 cctctcaggt tggcatcccc gggcggtgaa agcgaagccg gggtacgggg cggcgggtcc
    20341 gggggccgag acccggaccg ttcacagagc gtgacgaagg cgaacgcaac ggatccggac
    20401 tacagggcgg taccacccgg taggtactct ggcgggcatg cgcgcactcc tcgtggtcaa
    20461 cccagctgcc accaccacca gtgcgcggac ccgtgacgtg ctcattcacg cactggcgag
    20521 cgagatgaag ctggaagcgg tgaccaccga gtaccgcggg cacgcccagg acctcgggcg
    20581 ccgggccgcg gacagcgacg acatcgatct ggtggtcgcc ctgggcggcg acgggacggt
    20641 caacgaggtc gtgaacgggc tgctgcacaa gggccccgat gtggacagcc tgccgaagct
    20701 cgcggtggtt cccggcggct ccaccaatgt cttcgcgcgc gccctgggac tgcccaatga
    20761 cgccgtggag gcgaccggcg cgattctgga cgcactggag cagcggagcg agcgcacggt
    20821 cggcctgggg ctggcggccg gcaccccggg cacggcggac gaagccgttc cggaacgctg
    20881 gttcactttc tgtgccgggc tcggtttcga cgcgggagtc atcggccggg tcgaacagca
    20941 gcgcgagcgg ggcagacggt ccacccatgc cctgtacgta cgccaggtgg tgcggcagtt
    21001 ccttgaggag ccgcaccggc ggcacgggat gatcacgctg gaca
//
