LOCUS       NZ_LWKZ01000027        18701 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02923 scaffold7, whole genome shotgun sequence.
ACCESSION   NZ_LWKZ01000027
VERSION     NZ_LWKZ01000027.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02923
  ORGANISM  Streptomyces sp. CB02923
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 721891)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721891)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905005.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:56:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,128
            CDSs (total)                      :: 8,049
            Genes (coding)                    :: 7,904
            CDSs (with protein)               :: 7,904
            Genes (RNA)                       :: 79
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 32 of 145
            Pseudo Genes (incomplete)         :: 128 of 145
            Pseudo Genes (internal stop)      :: 11 of 145
            Pseudo Genes (multiple problems)  :: 22 of 145
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 703190
            Orig. end                         :: 721891
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWKZ01000027.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18701
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="4"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..18701
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18701
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[14000:15824](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15824
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(507..1322)
                     /locus_tag="A6A06_RS38005"
                     /old_locus_tag="A6A06_30810"
     CDS             complement(507..1322)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241530.1"
                     /locus_tag="A6A06_RS38005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30810"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_073768241.1"
                     /transl_table=11
                     /translation="MAGVARRRLDAELVRRKLARSREHAGQLITAGRVTVGGTTATKSA
                     TQVETSAALVVREDDNDPDYVSRGGHKLAGALAAFEPLGLKVAGRRALDAGASTGGFTD
                     VLLRAGAGHVVAADVGYGQLAWSLQSDDRVTVKDRTNVREMTLEQVDGEPVDLVVGDLS
                     FIPLGLVLPALVRCAAPDADLVLMVKPQFEVGKERLGSGGVVRSTELRAEAVRGVAERA
                     AALGLGVAGVTASPLPGPSGNVEYFLWLRAGADALDPADVDRAVAEGPR"
     gene            complement(1330..1680)
                     /locus_tag="A6A06_RS38010"
                     /old_locus_tag="A6A06_30815"
     CDS             complement(1330..1680)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984791.1"
                     /locus_tag="A6A06_RS38010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30815"
                     /product="hypothetical protein"
                     /protein_id="WP_073768242.1"
                     /transl_table=11
                     /translation="MEEPREPVTGAVPDGTGPAATDADGPEPEQPAPDGPTGPQPLGVD
                     VTPTGDAAVDAQLRRLADADHLAASGHLEVYEDVHRGLRDALAELDRRPGLAGPSGAPP
                     SPQPSATYDNRS"
     misc_feature    1744..1758
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            1757..2104
                     /locus_tag="A6A06_RS38015"
                     /old_locus_tag="A6A06_30820"
     CDS             1757..2104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719006.1"
                     /locus_tag="A6A06_RS38015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30820"
                     /product="sterol-binding protein"
                     /protein_id="WP_073768244.1"
                     /transl_table=11
                     /translation="MATLEECRAALGRLAQNLSTANGDVRGAAALDRSLSCRITDLDVT
                     FVGRLANGSLEDVTSVPGPPPERAQIRLTMRGDDLVAMVDGELHFAKAWGSGRIKLEAG
                     LRDMLRLRALL"
     gene            complement(2246..3073)
                     /locus_tag="A6A06_RS38020"
                     /old_locus_tag="A6A06_30825"
     CDS             complement(2246..3073)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263328.1"
                     /locus_tag="A6A06_RS38020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30825"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199931397.1"
                     /transl_table=11
                     /translation="MSRLLAENVTLAYDQRVIAQDLSVAVPDQSFTVIVGPNACGKSTL
                     LRALSRMLKPAAGSVLLDGSAISSLPAKKVARTLGLLPQSSIAPDGITVADLVARGRYP
                     HQGLLRQWSGEDERIVRESMEATGVGELAERYVDELSGGQRQRVWIAMALAQQTPLLLL
                     DEPTTYLDIQHQIEVLDLCAELHEEQGRTLVAVLHDLNHAARYATHLIAMRAGEIVAEG
                     PPEQVVTADLVEQVFGLKCQVIDDPETGTPLVVPAARKARTAAGVGAGAGAGA"
     gene            complement(3223..4368)
                     /locus_tag="A6A06_RS38025"
                     /old_locus_tag="A6A06_30830"
     CDS             complement(3223..4368)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984794.1"
                     /locus_tag="A6A06_RS38025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30830"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_073768249.1"
                     /transl_table=11
                     /translation="MNSTVKTDTAGTGSAGADSGGTDTAGTGRAAVAAKTGRAVRAVRT
                     AGGLSVRLDVRTLVVSVLLAAVALFASVLLIGTGDFPMTPADVLATLTGSGTTAQEFIV
                     NDLRLPRVLVALLVGAAFGIAGAVFQAVARNPLGSPDVLGFSQGSTVGALLVVVFFQGG
                     TFAIAAGSVVGGIVTGLVIFLLAWKGGIHGYRFVLVGIGAAAMLYAIVLYLMTKADIVE
                     ATQAVTWMTGTLSGRDWDQVWPLAIVCAVLIPLSLLYGRPLRMLEMGDDAAYALGVRVT
                     RVRVVLLAAAVLLVASATAAAGPIAFLALTAPQLARRLTRSPGPNLLPAALMGAALLVT
                     ADWASQQIFGADQLPVGVLTGLLGGGYLLWLLASERKAGRI"
     gene            complement(4365..5408)
                     /locus_tag="A6A06_RS38030"
                     /old_locus_tag="A6A06_30835"
     CDS             complement(4365..5408)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984795.1"
                     /locus_tag="A6A06_RS38030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30835"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_199931398.1"
                     /transl_table=11
                     /translation="MLVDSPPEAANAPAAPRRRQITRSAGLVAAVGALLVVIVLGIAVG
                     AKQVPLDQVWHALFHYTGDDTDVIVRDVRLPRTLLGLLAGAALGLAGTVMQALTRNPLA
                     DPGVLGINAGASAAVVSAISFLGITSLTGYVWFAFLGAAVVSVAVYVLGGTRSATPVRL
                     ALAGTALSAVLIGYINAVNLLDTAALDRMRFWTVGSLASATMTTVQEVAPFLVAGAVLA
                     LAVGRPLNAIALGDDQARALGARLTRTRALAMVAVTLLCGGATAACGPIVYVGLMVPHV
                     VRAVTGPDLRWILPYSAILSPVLLLGADVLGRVVARPGEIQVGIVTAVIGGPVFIYLVR
                     RRRMAQL"
     misc_feature    complement(5414..5432)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.03"
                     /tool="antismash"
     gene            5595..6620
                     /locus_tag="A6A06_RS38035"
                     /old_locus_tag="A6A06_30840"
     CDS             5595..6620
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984796.1"
                     /locus_tag="A6A06_RS38035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30840"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_073768251.1"
                     /transl_table=11
                     /translation="MSTPRSVSLSRRGVLAAGGAVGIGALLAACGGGKDSGSQGNVKGG
                     AWSFTDDRKKKVSLDHTPQRIVAFTGTAAALYDFGIDKQVVGVFGPTTLKDGKPDPQAG
                     DIDVDRLTVIGNTYNQFAVEKYAGLNPDLLITNMFEPNALWFVPDESKDKITKLAETVA
                     IAASRTPLVKIIERYAELAQSLGADLKAKKVTDAKARFEKAAAELRKAAKSNPVRVLAC
                     SGSADLFYASNPGISADIMYFKSLGVDIIVPDNLDKGGYFENLSWENADKYPADVLLLD
                     NRTSTLQPKDLAAKPAWNKLPAVKAGQVTGWSSEPRFSYAGAAPLMEELAKVIQNAKKV
                     A"
     gene            6715..7605
                     /locus_tag="A6A06_RS38040"
                     /old_locus_tag="A6A06_30845"
     CDS             6715..7605
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984797.1"
                     /locus_tag="A6A06_RS38040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30845"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_073768253.1"
                     /transl_table=11
                     /translation="MTTTAAPATTPYRFFDVHVVRTRRLGPSMVRITFGGERLGELASG
                     GRDQRFKLFLPQAHQAEPDFADQSENWYPAWRAQDPAERPLMRSYTIREQRHEPAEIDV
                     DFALHGADAPGAAVGGPASRWAASAVPGDRVSVLGPAVEDNGGVDFRPPPGTDWILLTG
                     DETALPAVAGILAWLSPGTQAKVFLSVAHAADRQDLPTFADADITWLVADEQPAAGQDA
                     LLEAVRTAELPAGTPYAWIAGEAGNVKMLRRHLVREREFDRRAVKFTGYWRRGASEEDL
                     LAEFVAGTAAPADED"
     gene            complement(7723..8751)
                     /locus_tag="A6A06_RS38045"
                     /old_locus_tag="A6A06_30850"
     CDS             complement(7723..8751)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015661458.1"
                     /locus_tag="A6A06_RS38045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30850"
                     /product="HAD-IIA family hydrolase"
                     /protein_id="WP_073768255.1"
                     /transl_table=11
                     /translation="MSERVRKQPGRCERALSEAYDTALLDLDGVVYAGGSVIEHAVASL
                     TTARDGGMHLAYVTNNASRTPDAVADQLTGFGLPTAPTDVITSAQAVARLIAGQVPEGA
                     PVLAIGGEGLRVALRERGLVPVDSVTDDPAAVVQGFDPKLDWERLAEAAYAVQRGVPWF
                     ASNTDLTIPKERGIAPGNGALVEVVRTATGGAPQVAGKPETPMHRETVLRTGAQRPLVI
                     GDRLDTDIEGAYNGGVDSLLVLTGVTTAAELLAAPPRHRPTYVDADLRGVLGPQPEVSG
                     ETDGGFRCGGWTASVRDGALALDGEGAPLDGLRALCAAAWTAAGDGSCDADAGKALARL
                     GL"
     misc_feature    8839..8850
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            8896..10158
                     /locus_tag="A6A06_RS38050"
                     /old_locus_tag="A6A06_30855"
     CDS             8896..10158
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576369.1"
                     /locus_tag="A6A06_RS38050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30855"
                     /product="DUF1015 domain-containing protein"
                     /protein_id="WP_073768257.1"
                     /transl_table=11
                     /translation="MTSTDGLRLHPFRGLRYAPDRVSSLTAVTSPPYDVVVRPDGVRHL
                     ETADPYNIVRLILPQAPDPATRHRQAADTLHRWRAEGVLTPDDRPALYVYEQSKDGLLQ
                     RGLIGALELDGPVLPHEDVIPEVVEDRAALMHAAHANFEPLLLSYVGQGAGNGATGVIE
                     RAVLTTPLLATTTEDGFAHRLWAVTDPADLTAVDEDLALRHALIADGHHRWATYQRLRE
                     EHPGDGAANPWATGLVLLVDSARHPLQVRAIHRVLPHLPLDDALSRLGDAFRVRPVDGP
                     LDTALAALDETTGSAFLLASGPERFCLLDRPDPQLLDETIRRDRPTVWRELDATVLHSF
                     LLDEVWRIRDHPSEISYLHSAGDAVEQAAKHGGTAVLMRPVLEQTVRQLALAGVTMPRK
                     STSFGPKPATGLVLRVLDDEV"
     misc_feature    10298..10316
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 33.62"
                     /tool="antismash"
     misc_feature    10367..10381
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.17"
                     /tool="antismash"
     gene            10429..12030
                     /locus_tag="A6A06_RS38055"
                     /old_locus_tag="A6A06_30860"
     CDS             10429..12030
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984800.1"
                     /locus_tag="A6A06_RS38055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30860"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_073768259.1"
                     /transl_table=11
                     /translation="MSLLAHSAEDPSPAARTGAPDSRSQLFNDSTTEHYRRSVAEGVDR
                     IADKISGTERPFTGVTVDGLSPTVAGIDLEQPLHDPAAALDELEEVYLRDAVYFHHPRY
                     LAHLNCPVVIPALVGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTARRIGLGERADGI
                     FTSGGTQSNLQAMLLARDEACRTALARENNPDESIPGEEPQGVATAVRRTDILPRLRIF
                     ASQVGHFSIEKAATLLGLGAEAVIAVPCGPDKRMRADALAAELARCEAEGLIPMAVVAT
                     AGTTDFGSIDPLPDVADLCARYGAWMHVDAAYGCGLLVSRRRALLDGIERADSVTVDYH
                     KSFFQPVSSSAVLVRDHATLRHVTYHADYLNPARMAERRIPNQVDKSIQTTRRFDALKL
                     WLTLRTMGADGIGELFDEVVDRAADAWKILNDDPRFEVVVEPQLSTLVFRYLPYTDDRD
                     PVLSDEVNLHAREALFASGDAIVAGTVVDGRHFLKFTLLNPETTLADIATVLDLIAEHA
                     GAYLAARPEPALSAAS"
     gene            12116..13438
                     /locus_tag="A6A06_RS38060"
                     /old_locus_tag="A6A06_30865"
     CDS             12116..13438
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984801.1"
                     /locus_tag="A6A06_RS38060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30865"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_073768261.1"
                     /transl_table=11
                     /translation="MSAPHDFIAIGLGPFNLGLACLTEPIDELDGLFLDNKPSFDWHPG
                     MMLETSTLQVPFMADLVTLADPTSPFSFLNYLKESGRMYSFYIRESFYPLRAEYNDYCR
                     WAAAKLDSVRFGHQVTTVEYDETEQVYVVHADHLPTGGKKTYRARKLVLGTGTPPHIPE
                     ACQGLGGDFAHNADYLENKAALQAKESITVVGSGQSAAEIYLDLLQDIDSHGYHLTWAT
                     RSARFFPLEYTKLTLEMTSPEYVDYFHALPPATRDRLNAQHKNLYKGIDSELINEIFDL
                     LYQKNLHGPCPTRLLTNTALSEAGYDATSGTYTLGLRQEEQGQDFTLATQGLVLATGYR
                     YRTPEFLAPVTDRIAWDDAGRYAVARNYSVDTAGHDIFVQNAELHTHGFVTPDLGMAAY
                     RNSCIIRELLGREYYPVEKSIAFQEFAAPAGPHHPVEVSPV"
     misc_feature    12126..12141
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.34"
                     /tool="antismash"
     gene            13435..14007
                     /locus_tag="A6A06_RS38065"
                     /old_locus_tag="A6A06_30870"
     CDS             13435..14007
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984802.1"
                     /locus_tag="A6A06_RS38065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30870"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_073768263.1"
                     /transl_table=11
                     /translation="MTAPVFTRTHASLGEFALRPVDPAGDAELLHGWVTHPKAVYWMMQ
                     DADLAAVEKEFARIGADPYHDAFIGLHNGVPAFLMERYDPAHREVTEVHEAAPGDVGMH
                     FLTAPTDAPVHGFTLAVITTVMDALFAEPGNRRVVVEPATGNTAVHALNKAVGFEIERT
                     VTLPKGEAYLSTCTRDQFLAARGENPC"
     gene            14001..15824
                     /locus_tag="A6A06_RS38070"
                     /old_locus_tag="A6A06_30875"
     CDS             14001..15824
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984803.1"
                     /locus_tag="A6A06_RS38070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30875"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_073768265.1"
                     /sec_met_domain="IucA_IucC (E-value: 8.7e-78, bitscore:
                     256.5, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNPTADTTEAATRDAVRHLTPELWARANRLLVRKALAEFAHERL
                     LTPQRLPQDGHYVVRSDDDRVEYRFTARRMGLDHWHIDADDITRRRDGAEAPLDALDFF
                     IELRRTLALSDDILPVYLEEISSTLSGTAYKLAAGPASAAELAKGDFQAIETGMSEGHP
                     CFVANNGRLGFGVHEYHAYAPEAAGPVHLVWLAARRDRSTFTAGEDLDYDRLVRDELGA
                     ATLDRFAATLGDLGLDLADYHLIPAHPWQWWNKLSVTFAAEVAQQHLICLGPGDDAYLA
                     QQSIRTFFNTSDPSKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLANLIASDETFR
                     AARFSIIRERAAVGYHHRQYEAATAKGSPYLKMLAALWRESPVPTLEPGQRVATMASLL
                     HTDPEGGSLAAALIEESGLEPADWLRRYADAYLTPVLHAFYAYDLVFMPHGENVILVIE
                     DGTVQRAIFKDIAEEIAVMDPDAVLPPAVERIRADVPEDKKLLSLFTDVFDCFFRFLSG
                     ILVTNDVLDEDTFWRTVADCVTAYLEANPQLADKFRQYDMFADEFALSCLNRLQLRNNE
                     QMVDLQDPAGALQLIGTLENPIARFAPAAGE"
     gene            complement(15920..16771)
                     /locus_tag="A6A06_RS38075"
                     /old_locus_tag="A6A06_30880"
     CDS             complement(15920..16771)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008409152.1"
                     /locus_tag="A6A06_RS38075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_30880"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_199931416.1"
                     /transl_table=11
                     /translation="MPIPDDVTGEEIDKDVRQELLSLPKTLADDVARNLVMVAKLLDED
                     PEQAYGFSRVALRLASRVPAVREAAGFAAYAVGKYGEALAEFRAARRMTGSVELWPVMA
                     DCERGLSRPEKALAMAGEPEVQKLDRAGQVEMRLVAAGARRDMGQADAAVVTLQSPELA
                     SNSVQPWTARLRYAYADALLEVGREDEAREWFAKALEADQGGTTNASDRLAELDGVEFT
                     DALEDEDETESAGEAGDVTETAAPAQRDGSEASEAPDAPEAAATEGAAPADAPREERPE
                     QG"
     gene            16829..17830
                     /locus_tag="A6A06_RS42405"
     CDS             16829..17830
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS42405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199931417.1"
                     /transl_table=11
                     /translation="MPEPTAVTAVVTATPGAVRTPPAPVVVPAEAATVATAIVTAVITA
                     EAAAVVVAARATVVTAEATATVVTAAAVAATGGATATVIVPTGTTIVTAETTAVIVTAR
                     TAIVTAETTAVVITARATVIATEAATTVVTAAAVAATGGTTATVIITARATVVTAEAAT
                     AVVVPTGTTVVPAEAATVIVTAEAAATVVPARAAAVATTGGATATVIVTTGTAIVTAET
                     ATVVVAAEAAATVVPARAAAVATTGGATATVIVPTRTTVVPAEAAAAVVVAARATVVTA
                     EATATVVTAAAEAATGGATATVIVTARTARTVVAAGAAVVVTAGAAGPTVVT"
     misc_feature    complement(18100..18115)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     rRNA            complement(18233..18349)
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="A6A06_RS38085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="A6A06_30885"
                     /product="5S ribosomal RNA"
     gene            complement(18233..18349)
                     /gene="rrf"
                     /locus_tag="A6A06_RS38085"
                     /old_locus_tag="A6A06_30885"
     misc_feature    18304..18319
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     rRNA            complement(18472..>18701)
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="A6A06_RS38090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="A6A06_30890"
                     /product="23S ribosomal RNA"
     gene            complement(18472..>18701)
                     /locus_tag="A6A06_RS38090"
                     /old_locus_tag="A6A06_30890"
ORIGIN
        1 gctgccgttg ttgcgtacga ggacatcgat ggtcatccgc tcctcgacct cgtaggcgcg
       61 ggtcacgacc cggtcgacga ccttgtccag gtcgtcccgt tcggcctccg ccaggaagcc
      121 gacccggccg aggttgacgc cgagcatcgg caccccggac gtccgggcga agtccgcgcc
      181 gcgcagcagc gtcccgtccc cgccgaggac caccagcagt tcgcagccct cggccgcgca
      241 ctgctcggac tcgacgcgta ccacggacgc cggaagcggc aggtcggcgg cctcttcggc
      301 caggacgcgt acgccgatgc cgctgcgcag gagtccctgg acgacgagtt cggcgctgcg
      361 gacggccgcg gggcggccgg tgtgggcgag caggaagaca gtgcgttcgc cgttctccgc
      421 ggacggcgca gggccgtccg acgacggtgc ggtacaggtg gtgcgcgaga cggctgcttc
      481 agccgctccg gaagctgcag aactggtcaa cggggcccct ccgccactgc tcggtcgacg
      541 tccgccgggt ccagtgcatc cgccccggcg cgcagccaca gaaagtactc gacattgccg
      601 gagggtccgg gcagcgggct ggcggtcacg ccggccacgc ccagtcccag cgcggcggcc
      661 cgctctgcga cgccgcgtac cgcctcggcc cgcagttcgg tgctgcgcac cactccgccg
      721 ctgccgaggc gctccttgcc cacctcgaac tgcggcttga ccatcagcac caggtcggcg
      781 tcgggggccg cgcagcggac gagggcgggc agcaccaggc ccagcgggat gaacgacagg
      841 tcgcccacga cgaggtcgac gggctcgccg tcgacctgct ccagcgtcat ctcgcgcacg
      901 ttggtgcggt ccttgaccgt gacccggtcg tcgctctgca gcgaccaggc gagctgtccg
      961 tacccgacgt cggcggcgac gacgtgtccc gcgccggccc gcagcaggac gtccgtgaag
     1021 ccgccggtgg acgcgcccgc gtcgagcgcg cggcggcccg ccaccttcag gccgaggggt
     1081 tcgaacgcgg cgagggcccc ggccagcttg tggccgccgc gcgagacgta gtccgggtcg
     1141 ttgtcgtcct cgcgcacgac cagggccgcg ctggtctcca cctgggtggc ggacttggtc
     1201 gccgtcgtcc cgccgacggt cacccgcccc gcggtgatca gctggcccgc gtgctcgcgt
     1261 gagcgggcca gcttgcggcg caccagctcc gcgtcgagtc ggcgtcgtgc cactcctgcc
     1321 acctgaggtt cagctcctgt tgtcgtacgt tgcggacggc tgcggggacg ggggcgcgcc
     1381 ggacgggccg gcgagcccgg ggcgccggtc gagctcggcc agcgcgtcgc gcagcccccg
     1441 gtgcacatcc tcgtacacct ccaggtgccc gctcgcggcg aggtggtcgg cgtcggccag
     1501 gcgccgcagc tgggcgtcca cggcggcgtc cccggtgggc gtgacgtcga cgccgagcgg
     1561 ctgcggcccg gtggggccgt ccggcgccgg ctgctccggc tccgggccgt ccgcgtccgt
     1621 ggcggccggg cccgtgccgt ccggcaccgc gccggtcacc ggctctctcg gctcttccat
     1681 gccttgacgc tacctcgaac agcccgcgga ccgggccacc gcccgcccgc cccgcaccgg
     1741 cgtatcgtcg atctcgatgg caaccctcga agagtgccgt gccgccctcg gccggctcgc
     1801 acagaacctc tccaccgcga acggcgacgt ccgaggcgcg gccgcgctgg accgttcgct
     1861 cagctgccgg atcaccgacc tggacgtgac cttcgtcggg cggctggcga acggcagcct
     1921 ggaggacgtc accagcgtcc ccggtccgcc tcccgaacgg gcccagatcc gcctgacgat
     1981 gcgcggcgac gacctggtgg ccatggtcga cggcgagctg cacttcgcca aggcgtgggg
     2041 cagcggccgg atcaagctgg aagccggcct gcgcgacatg ctgcgcctgc gcgcactcct
     2101 ctgaccgcgg cccgccgcac cggacagcta ccgggcggcc accgaacggc agcctgggcc
     2161 cgcccggccc atcgcgccgg acggccggat acgcaccgga cagccggata cgcgcccggc
     2221 gggccgaacc agctcccaac cgtcctcagg cccccgcgcc cgcccccgcg cccacacccg
     2281 cagccgtacg ggccttgcgc gccgccggga cgaccagcgg agtgccggtc tccggatcgt
     2341 cgatgacctg gcacttcagg ccgaagacct gctcgacgag gtcggccgtg acgacctgct
     2401 ccggcggccc ctcggcgacg atctcaccgg cgcgcatggc gatcaggtgg gtggcgtagc
     2461 gcgcggcgtg gttgaggtcg tgcaggacgg cgacgagggt gcggccctgc tcctcgtgca
     2521 gttcggcgca caggtccagc acctctatct ggtgctggat gtcgaggtag gtggtcggct
     2581 cgtccaggag gagcagcggt gtctgctggg cgagcgccat cgcgatccac acgcgctgcc
     2641 gctgtccgcc ggagagttcg tcgacgtaac gttcggccag ttcgccgacg ccggtcgcct
     2701 ccatcgactc ccgtacgatc cgctcgtcct cgcccgacca ctggcgcagc agtccctgat
     2761 gcgggtagcg gccgcgggcc accaggtccg cgacggtgat cccgtcgggc gcgatggagg
     2821 actgcggcag caggccgagg gtgcgggcga ccttcttggc gggcagcgac gagatggccg
     2881 agccgtccag cagtacggag ccggcggccg gcttgagcat ccgcgacagg gcgcgcagca
     2941 gcgtggactt gccgcaggcg ttcggtccga cgatgaccgt gaaggactgg tccggtacgg
     3001 ccaccgagag gtcctgggcg atgacccgct ggtcgtaggc gagggtcacg ttctcggcca
     3061 agagacggct cactgcgttg ctccttgtag cggtctgcgt cgtgggggcc tggggcggct
     3121 cggtcggtgt cgcgggggcg ggggccggtg cggacccccc ggaggccggt gcggaccccc
     3181 gcagagcgtt ctgtgtgctc atatccggcc cgcccggcgt gctcatatgc gcccggcctt
     3241 gcgctcggag gccagcagcc acagcaggta gccgccgccg agcaggccgg tcagcacgcc
     3301 caccgggagc tggtcggcgc cgaagatctg ctgcgaggcc cagtcggcgg tgaccaggag
     3361 ggcggcgccc atgagggcgg cgggcagcag gttggggccg ggcgagcggg tcagccgacg
     3421 ggccagctgc ggcgcggtca gcgcgaggaa ggcgatcggt ccggccgccg cggtcgccga
     3481 ggcgaccagc agcacggccg ccgccagcag gacgacgcgc acccgggtga cgcggacgcc
     3541 cagcgcgtac gcggcgtcgt cgcccatctc cagcatgcgc agcggccgcc cgtagagcag
     3601 ggacagcggg atcaggacgg cgcagacgat ggccagcggc cagacctggt cccagtcccg
     3661 gccgctgagg gtgccggtca tccaggtgac ggcctgcgtc gcctcgacga tgtccgcctt
     3721 ggtcatcagg tacaggacga tggcgtagag catcgcggcg gcgccgatgc cgacgagcac
     3781 gaagcggtag ccgtggatgc cgcccttcca ggccagcagg aagatcacca gcccggtgac
     3841 gatgccgccg acgaccgagc ccgcggcaat cgcgaaggtg ccgccctgga agaagacgac
     3901 gacgagcagc gcgccgaccg tcgacccctg ggagaagccc agcacgtcgg ggctgcccag
     3961 cgggttgcgg gcgacggcct ggaagaccgc gccggcgatg ccgaaggcgg cgccgaccag
     4021 cagggcgacc aggacccgcg gcagccgcag gtcgttgacg atgaattcct gggcggtggt
     4081 gccggagccg gtgagggtgg cgaggacgtc cgccggggtc atcgggaagt cgccggtgcc
     4141 gatcagcagc acgctcgcga acagggccac ggccgccagc agcacggaga ccacgagggt
     4201 ccgtacgtcc aggcgcactg acagcccgcc ggcggtgcgg accgcccgta cggcccggcc
     4261 ggtcttcgcg gccacggcgg cccgaccggt cccggcggtg tcggtcccgc cgctgtcggc
     4321 cccggcgctg ccggttccgg cggtgtcggt cttgacggtg gaattcacag ctgggccatc
     4381 ctccgacgcc gtacgagata gatgaagacc gggccgccga tgacggccgt cacgatgccg
     4441 acctggatct cgccgggccg cgccacgacg cgccccagga cgtcggcgcc gagcagcagg
     4501 accggcgaga ggatcgcgga gtacggcagg atccaccgca ggtcggggcc ggtgacggcg
     4561 cggacgacgt gcgggaccat caggccgacg tagacgatcg gcccgcaggc ggcggtcgcg
     4621 ccgccgcaca gcagggtgac ggcgaccatc gccagcgccc gggtgcgggt cagccgggcg
     4681 cccagggccc gcgcctggtc gtcgccgagc gcgatggcgt tcagggggcg tccgacggcg
     4741 agcgccagga cggcgccggc cacgaggaac ggcgcgacct cctgcacggt ggtcatggtg
     4801 gcggaggcca gtgagccgac cgtccagaag cgcatccggt ccagcgccgc ggtgtccagg
     4861 aggttgacgg cgttgatgta gccgatcagc acggcggaca gggcggttcc ggcgagggcg
     4921 agccgtacgg gggtggcgct gcgggtgccg ccgagcacgt acacggcgac ggagacgacg
     4981 gcggcgccga ggaaggcgaa ccacacgtat ccggtcagcg aggtgatccc caggaagctg
     5041 atggcggaga cgacggccgc cgaggcgccc gcgttgatgc cgagcacgcc cgggtcggcg
     5101 agggggttgc gggtcagtgc ctgcatcacc gtgccggcca ggcccagggc cgcgccggcc
     5161 agcaggccga ggagggtgcg cggcaggcgt acgtcccgca cgatcacgtc ggtgtcgtca
     5221 cccgtgtagt ggaagagggc gtgccacacc tggtcgaggg gtacctgttt cgcgccgacg
     5281 gcgataccca ggacgatgac gaccagcagc gctccgacgg cggcgacgag ccccgccgag
     5341 cgagtgatct gccgccgtcg cggtgccgcg ggggcgtttg ctgcttcggg gggactgtca
     5401 accaacacgg gagttaggtt agcctaccct cacgatcaga catcaagtcg ttccgcaggg
     5461 ccttttaccg gccctttgcc gtacgtgctg aagtccgacc ggaaacatac cgaagaccgt
     5521 gaacgaccgg ccgaagtccc gtcaaggccc gcccggccga gccggggccc agcccagaga
     5581 gaagcgcatc agccatgagc accccccgca gcgtatccct gtcccgacgc ggcgtcctcg
     5641 ccgccggtgg cgccgtcggt atcggcgcgc tgctggccgc ctgcgggggc ggcaaggact
     5701 cgggctcgca ggggaacgtc aagggcggcg cctggtcctt cacggacgac cgcaagaaga
     5761 aggtctccct cgaccacacg ccgcagcgca tcgtcgcctt caccggcacc gcggccgcgc
     5821 tgtacgactt cggcatcgac aagcaggtcg tcggcgtctt cggcccgacc acgctcaagg
     5881 acggcaagcc cgacccgcag gccggcgaca tcgacgtgga ccggctcacc gtcatcggca
     5941 acacgtacaa ccagttcgcg gtcgagaagt acgcgggcct caaccccgac ctgctgatca
     6001 ccaacatgtt cgagccgaac gccctgtggt tcgtgccgga cgagagcaag gacaagatca
     6061 ccaagctggc cgagacggtg gccatcgccg cgtcccggac cccgctggtg aagatcatcg
     6121 agcggtacgc cgaactggcg cagtccctcg gcgcggacct gaaggccaag aaggtcaccg
     6181 acgccaaggc ccgcttcgag aaggccgccg ccgaactgcg caaggccgcc aagtccaacc
     6241 cggtccgggt gctcgcctgc tccggcagtg ccgacctctt ctacgcctcc aaccccggca
     6301 tcagcgccga catcatgtac ttcaagtcgc tgggcgtgga catcatcgtc cccgacaacc
     6361 tggacaaggg cggctacttc gagaacctga gctgggagaa cgccgacaag tacccggccg
     6421 acgtcctcct gctcgacaac cgcacctcca ccctccagcc caaggacctg gccgccaagc
     6481 ccgcctggaa caagctgccc gccgtcaagg ccggtcaggt cacgggctgg tccagcgagc
     6541 cgcgcttctc ctacgcgggc gccgcgccgc tgatggaaga gctggccaag gtcatccaga
     6601 acgccaagaa ggtcgcctga cgccgaccgg ctccggccgc cgcaccggcc ggcaacggca
     6661 ccgcgccgca ccccaccgca gtcaccgagt cacgcttccg ggaggttcct ccgcatgacc
     6721 acgaccgccg cacccgccac caccccgtac cgcttcttcg acgtgcacgt cgtgcgcacc
     6781 cggcggctcg gaccctccat ggtccggatc accttcggcg gcgaacggct cggcgaactg
     6841 gcctccggcg gccgtgacca gcgcttcaaa ctgttcctcc cgcaggccca ccaggccgag
     6901 ccggacttcg ccgaccagag cgagaactgg taccccgcct ggcgcgccca ggacccggcc
     6961 gagcggccgc tgatgcgctc gtacacgatc cgcgagcagc gccacgagcc ggccgagatc
     7021 gacgtggact tcgcgctgca cggcgcggac gccccgggtg ccgcggtcgg cggcccggcc
     7081 tcgcgctggg cggcgtccgc cgtgcccggc gaccgcgtct cggtcctcgg cccggccgtc
     7141 gaggacaacg gcggcgtcga cttccgcccg ccgcccggca ccgactggat cctgctgacc
     7201 ggcgacgaga cggcgctgcc cgccgtggcc ggcatcctgg cctggctctc ccccggcacc
     7261 caggccaagg tcttcctgtc cgtcgcccac gcggccgacc gccaggacct gcccaccttc
     7321 gccgacgccg acatcacctg gctggtggcc gacgagcagc cggcggccgg gcaggacgcg
     7381 ctgctggagg cggtccgtac cgccgaactg cccgcgggca cgccgtacgc ctggatcgcg
     7441 ggcgaggcgg gcaacgtgaa gatgctccgc cggcacctcg tgcgggagcg ggagttcgac
     7501 cgccgggccg tgaagttcac cggttactgg cggcgcggcg ccagcgagga ggacctgctc
     7561 gcggagttcg tggcgggcac ggcggcgccc gccgacgagg actgaaccgg cccccgtacc
     7621 gtgcgtgtac gacggtccgt acacgcacct gagggagggg ccccgctcat caccgagcgg
     7681 ggcccctccc ctcttcgtac gccgtccgtc acggcgcgcg cctcacagac cgagccgcgc
     7741 cagcgccttg cccgcgtcgg cgtcgcaact gccgtcgccc gccgccgtcc aggccgccgc
     7801 gcacagcgcc cgcaggccgt ccagcggcgc gccctcaccg tccagcgcca gcgcgccgtc
     7861 gcgtacggac gccgtccagc cgccgcaccg gaatccgccg tccgtctccc cggacacctc
     7921 cggctgcggg ccgagcacac cgcgcaggtc cgcgtccacg tacgtggggc ggtgccgcgg
     7981 cggagcggcc agcagttcgg cggcggtggt cacgccggtg agcaccagca gcgagtcgac
     8041 gccgccgttg taggcgccct cgatgtccgt gtcgagccgg tcgccgatca ccagcggccg
     8101 ctgcgcgccc gtacgcagca ccgtttcacg gtgcatgggc gtctccggct tgcccgccac
     8161 ctggggcgcg ccgccggtgg cggtccgtac gacctccacc agggcgccgt tgcccggcgc
     8221 gatcccgcgc tccttgggga tggtcaggtc cgtgttcgag gcgaaccagg gcacgccgcg
     8281 ctgtacggcg tacgcggctt ccgccagccg ttcccagtcc agtttcggat cgaatccctg
     8341 caccacggcg gccgggtcgt ccgtcacgga gtccaccggg accagcccgc gctcgcgcag
     8401 cgccacccgc agtccctcgc cgccgatcgc cagcaccggc gcgccctcgg gcacctgccc
     8461 ggcgatcagc cgggcgaccg cctgcgccga ggtgatgacg tcggtcggcg cggtgggcag
     8521 cccgaatccg gtgagctggt ccgcgaccgc gtccggcgtc cgggaggcgt tgttggtcac
     8581 gtacgccagg tgcataccgc cgtcccgggc cgtggtgagc gacgcgacgg cgtgctcgat
     8641 caccgagccg ccggcgtaga cgactccgtc caggtccagc agcgccgtgt catacgcctc
     8701 actcagtgcc cgttcgcacc gtccgggctg cttgcgcacc cgctcgctca tgccgtttcg
     8761 ctccttatgc gcagaggtac agaggccggt ctgcgggccg ccgaaaagcg gaacctcaca
     8821 taccggtata tccagcagga caacggtttc ccccctgatc atcccgcagt ccggcaggcg
     8881 gcatagcatt ccccaatgac cagcaccgac ggcctccgcc tccacccctt ccgcgggctg
     8941 cgctatgccc cggaccgcgt cagcagcctc acggccgtca cctcgccgcc gtatgacgtc
     9001 gtcgtacggc cggacggagt gcgccacctc gaaacagccg acccgtacaa catcgtccgg
     9061 ctcattctcc cgcaagcccc cgaccccgcg acccggcacc gccaggccgc cgacaccctg
     9121 caccgctggc gcgcggaagg cgtcctgacc ccggacgacc ggcccgccct ctacgtgtac
     9181 gaacagagca aggacgggct gctgcaacgc ggcctgatcg gcgcgctcga actcgacggc
     9241 cccgtcctgc cgcacgagga cgtgatcccc gaggtcgtcg aggaccgcgc cgccctgatg
     9301 cacgcggccc acgccaactt cgaaccgctg ctcctctcct acgtcggcca gggcgccggc
     9361 aacggcgcca ccggcgtcat cgaacgggcc gtcctgacca caccgctgct cgccaccacc
     9421 accgaggacg gcttcgccca ccggctgtgg gccgtcaccg accccgccga cctgaccgcc
     9481 gtcgacgagg acctggcgct gcggcacgcc ctgatcgccg acgggcacca ccgctgggcc
     9541 acctaccagc ggctgcgcga ggaacacccc ggcgacggcg cggcgaatcc ctgggcgacc
     9601 ggcctggtgc tgctcgtgga ctcggcccgc cacccgctcc aggtacgggc catccaccgc
     9661 gtactgccgc atctgccgct ggacgacgcg ctgtcccggc tgggcgacgc cttccgcgtc
     9721 cggccggtgg acggcccgct cgacacggcg ctggcggcgc tggacgagac gaccggcagc
     9781 gccttcctgc tggcgtcggg accggagcgg ttctgcctgc tggaccgccc cgacccgcag
     9841 ctgctcgacg agacgatccg ccgggaccgc cccacggtct ggcgcgagct ggacgccacc
     9901 gtcctgcact cgttcctgct ggacgaggtg tggcggatcc gcgaccaccc gtccgagatc
     9961 agctatctgc acagtgccgg ggacgccgtc gagcaggcgg cgaaacacgg cggtacggcc
    10021 gtgctgatgc gcccggtcct tgagcaaacc gtgcgccaac tcgcactggc cggggtgacc
    10081 atgccgcgca agtcgacgtc cttcggcccc aaaccggcca ccggtctggt gctgcgcgtc
    10141 ctggacgacg aggtctgatg cgggcggtgc gcacgcccgg cacggggcgt accggagcct
    10201 gattccaggc cgtgcagcct ccttgatgtc cgatgacggc ccggcgcggg tgacccgcgc
    10261 cggtgcctcg gcaccccttt ccctcccgcc acacaagtta ggttaggctt acctcatcac
    10321 gtagcggatg gagccgttcc cccctgcgcc gacggccttc tgcccaggca caggcgttcc
    10381 atgcgcatcc ccccacgtga gcaagtccgc atcagggagg acacgttcat gagtctcctc
    10441 gcgcactccg ccgaggaccc gtcgcccgcc gcacgcaccg gggcgccgga cagccggtca
    10501 cagctgttca acgacagcac caccgagcac taccgccgct ccgtcgccga aggcgtcgac
    10561 cgcatagccg acaaaatatc cggaaccgaa cgccccttca ccggcgtcac ggtcgacggc
    10621 ctctccccca cggtggccgg catcgacctc gaacaaccac tgcacgaccc cgccgccgcc
    10681 ctcgacgagc tcgaagaggt ctacctccgc gacgccgtct acttccacca cccgcgctac
    10741 ctcgcgcacc tcaactgccc ggtcgtcatc cccgccctgg tgggcgaggc ggtgctgtcc
    10801 gcggtcaact cctcgctgga cacctgggac cagagcgcag gcggcaccct catcgagcgc
    10861 cgtctgatcg actggaccgc ccggcgcatc ggcctcggcg agcgcgccga cggcatcttc
    10921 accagcggcg gtacgcagtc caacctccag gccatgctgc tggcccgcga cgaggcgtgc
    10981 cgtacggccc tcgcccgcga gaacaacccg gacgagagca ttccgggcga agaaccccaa
    11041 ggcgtggcaa ctgcggtacg ccgtaccgac atcctgcccc ggctgcgcat cttcgcctcc
    11101 caggtcggcc acttcagcat cgagaaggcc gccaccctgc tcggtctcgg cgcggaagcc
    11161 gtgatcgcgg tgccgtgcgg cccggacaag cggatgcggg ccgacgcgct cgccgccgag
    11221 ctggcacgct gcgaggccga gggcctgatc ccgatggcgg tcgtggccac cgcgggcacc
    11281 accgacttcg gcagcatcga cccgctgccc gacgtcgccg acctgtgcgc ccggtacggc
    11341 gcctggatgc acgtggacgc cgcgtacggc tgcggcctgc tggtctcccg ccgccgcgcc
    11401 ctcctggacg gcatcgaacg cgccgactcg gtgaccgtgg actaccacaa gtccttcttc
    11461 cagccggtca gctccagcgc cgtcctggta cgcgaccacg ccaccctgcg gcacgtcacg
    11521 taccacgccg actacctcaa cccggcgcgg atggcggagc ggcgtatccc caaccaggtc
    11581 gacaaatcga tccagaccac ccgacgtttc gacgcgctga aactgtggct gaccctgcgc
    11641 accatgggcg ccgacggcat cggcgaactc ttcgacgagg tcgtcgaccg cgccgccgac
    11701 gcctggaaga tcctcaacga cgacccgcgc ttcgaggtcg tggtcgagcc ccagctgagc
    11761 accctggtct tccgctacct gccgtacacc gacgaccggg acccggtgct gagcgacgag
    11821 gtcaacctgc acgccaggga agcgctgttc gcctccggag acgccatcgt cgcgggcacc
    11881 gtcgtcgacg gccggcactt cctcaagttc accctgctca accccgagac cacgctggcc
    11941 gacatcgcca cggtcctcga cctgatcgcc gagcacgccg gcgcgtacct cgccgcgcgc
    12001 cccgaaccgg ccctcagcgc cgcgagctga ccgtaccgcc gaccggcccc gccgcctcgt
    12061 cccccacgag ccgacacccc gcggccgacc gacaccccgc aaacggagac cccacgtgtc
    12121 cgcccctcac gatttcatcg ccatcggcct cgggcccttc aacctcggcc tcgcctgcct
    12181 gaccgagccc atcgacgagc tcgacggact gttcctggac aacaagccgt ccttcgactg
    12241 gcacccgggc atgatgctgg agaccagcac cctccaggtg ccgttcatgg ccgacctggt
    12301 caccctcgcc gacccgacct cgcccttctc cttcctgaac tacctgaagg aatcgggacg
    12361 gatgtactcc ttctacatcc gcgagagctt ctacccgctg cgcgccgagt acaacgacta
    12421 ctgccgctgg gccgccgcca agctggacag cgtccgcttc ggccaccagg tcaccaccgt
    12481 cgagtacgac gagaccgaac aggtctacgt cgtccacgcc gaccacctgc ccaccggcgg
    12541 gaagaagacc taccgcgccc gcaaactcgt cctcggcacc ggcaccccgc cgcacatccc
    12601 cgaagcctgc cagggcctcg gcggcgactt cgcgcacaac gccgactacc tggagaacaa
    12661 ggccgccctc caggccaagg aatccatcac cgtcgtcggc agcggccaga gcgcggcgga
    12721 gatctacctc gacctcctcc aggacatcga cagccacggc taccacctga cctgggccac
    12781 ccgctccgcg cgcttcttcc ccctcgaata caccaagctc acgctggaga tgacctctcc
    12841 ggagtacgtg gactacttcc acgccctgcc gccggccacc cgcgaccggc tcaacgccca
    12901 gcacaagaac ctctacaagg gcatcgactc cgagctgatc aacgagatct tcgacctgct
    12961 ctaccagaag aacctgcacg gcccctgccc gacccggctg ctgaccaaca ccgcgctcag
    13021 cgaagccggt tacgacgcga cctccggcac gtacaccctg ggcctgcgcc aggaggaaca
    13081 gggccaggac ttcaccctcg ccacccaggg cctggtgctg gccaccggat accggtaccg
    13141 gaccccggag ttcctcgccc ccgtcaccga ccgcatcgcc tgggacgacg ccggccgcta
    13201 cgcggtggcc cgcaactaca gcgtcgacac cgcgggccac gacatcttcg tgcagaacgc
    13261 cgagctgcac acccacggct tcgtcacccc cgacctgggc atggccgcgt accgcaactc
    13321 ctgcatcatc cgcgagctgc tcggccgcga gtactacccg gtcgagaagt ccatcgcctt
    13381 ccaggagttc gccgccccgg ccggcccgca ccaccccgtg gaggtctcgc ccgtatgacc
    13441 gcgcccgtct tcacccgcac ccacgcctcg ctcggcgagt tcgccctgcg cccggtcgac
    13501 ccggccggcg acgcggagct gctgcacggc tgggtcaccc accccaaagc cgtgtactgg
    13561 atgatgcagg acgccgacct ggcggccgtc gagaaggagt tcgcgcgcat cggcgccgac
    13621 ccgtaccacg acgccttcat cggcctgcac aacggcgtcc ccgccttcct gatggagcgc
    13681 tacgacccgg cgcaccggga ggtgaccgag gtccacgagg ccgcgcccgg cgacgtcggc
    13741 atgcacttcc tgaccgcgcc gaccgacgcg ccggtgcacg gcttcaccct cgccgtgatc
    13801 accaccgtca tggacgcgct gttcgccgag cccggcaacc ggcgcgtcgt cgtcgaaccg
    13861 gccaccggca acaccgcggt acacgccctc aacaaggccg tcggcttcga gatcgaacgc
    13921 acggtcaccc tgcccaaggg cgaggcgtac ctgagcacct gcacccgcga ccagttcctg
    13981 gccgcccgag gagaaaaccc atgctgaacc ccaccgcgga caccaccgag gccgcgacgc
    14041 gcgacgccgt ccgccacctc acccccgagc tgtgggcgcg cgccaaccgc ctcctcgtcc
    14101 gcaaggccct cgccgagttc gcccacgagc gcctgctgac accgcagcgg ctgccgcagg
    14161 acggccacta cgtcgtccgc agcgacgacg accgcgtcga gtaccgcttc accgcccgcc
    14221 ggatgggcct ggaccactgg cacatcgacg ccgacgacat cacccgccgc cgcgacggcg
    14281 ccgaggcccc cctggacgcc ctcgacttct tcatcgagct gcgccgcacc ctcgccctca
    14341 gcgacgacat cctcccggtc tacctggagg agatcagctc caccctctcc ggcacggcgt
    14401 acaagctggc cgccgggccc gcgtccgccg ccgaactggc gaagggcgac ttccaggcca
    14461 tcgagacggg catgtccgag ggccacccct gcttcgtcgc gaacaacggc cgcctcggct
    14521 tcggcgtgca cgagtaccac gcgtacgccc ccgaggccgc cggccccgtc cacctcgtct
    14581 ggctcgccgc gcgccgcgac cgctccacct tcaccgcggg cgaggacctg gactacgacc
    14641 ggctggtccg cgacgagctg ggcgccgcca ccctggaccg gttcgccgcc accctgggcg
    14701 acctcggcct ggacctggcc gactaccacc tcatccccgc ccacccgtgg cagtggtgga
    14761 acaagctctc cgtcaccttc gccgccgagg tcgcccagca gcacctgatc tgcctcggcc
    14821 ccggcgacga cgcgtacctg gcgcagcagt ccatccgcac gttcttcaac accagcgacc
    14881 cgtccaagca ctatgtcaag acggccctgt cggtcctcaa catgggcttc atgcgcggcc
    14941 tgtccgccgc ctacatggag gccaccccgg ccatcaacga ctggctggcg aacctgatcg
    15001 cgagcgacga gaccttccgg gccgcccgct tctcgatcat ccgcgagcgc gccgccgtcg
    15061 gctaccacca ccgccagtac gaggccgcca ccgccaaggg ctccccgtac ctgaagatgc
    15121 tcgccgccct gtggcgcgag agcccggtgc ccaccctcga acccggccag cgggtggcca
    15181 ccatggcctc cctgctgcac accgacccgg agggcggctc actggcagcc gccctgatcg
    15241 aggagtccgg gctggagccc gcggactggc tgcgccggta cgcggacgcc tacctcacgc
    15301 ccgtcctgca cgcgttctac gcctacgacc tggtcttcat gccgcacggc gagaacgtca
    15361 tcctggtcat cgaggacggc accgtacagc gcgcgatctt caaggacatc gccgaggaga
    15421 tcgcggtgat ggacccggac gcggtgctgc cgccggccgt cgagcggatc cgcgccgacg
    15481 tccccgagga caagaagctc ctctccctct tcacggacgt cttcgactgc ttcttccgct
    15541 tcctcagcgg catcctcgtc acgaacgacg tgctggacga ggacaccttc tggcgcaccg
    15601 tcgccgactg cgtcaccgcc tacctggagg ccaatccgca gctcgccgac aagttccggc
    15661 agtacgacat gttcgcggac gagttcgcgc tgtcctgcct caaccgcctc cagctgcgca
    15721 acaacgagca gatggtggac ctccaggacc cggcgggcgc cctccagctg atcggcacgc
    15781 tggagaaccc gatcgcccgt ttcgccccgg ccgccgggga gtgagacgcg cgtacacatg
    15841 agtgaagggc gggacccggc tgggtcccgc ccttcactca ttcactcatt caccgtcatg
    15901 cggccgggcc gccatggcct cagccctgct cgggacgctc ctcacggggc gcgtccgcgg
    15961 gggcggcgcc ttcggtggcc gccgcttcgg gggcgtcggg ggcttcggag gcttcggagc
    16021 cgtcccgctg cgcgggggcg gcggtctcgg tcacgtcacc ggcctcgccc gcggactcgg
    16081 tctcgtcctc gtcctccagt gcgtcggtga actccacgcc gtccagctcg gccagccggt
    16141 ccgaggcgtt cgtggtgccg ccctggtcgg cttccagcgc cttggcgaac cactcgcgtg
    16201 cctcgtcctc gcggccgacc tccaggagcg cgtcggcgta cgcgtagcgc aggcgggcgg
    16261 tccacggctg tacggagttc gacgccagct cggggctctg cagcgtcacg acggccgcgt
    16321 cggcctggcc catgtcacgc cgggcaccgg ccgcgaccag ccgcatctcg acctggcccg
    16381 cccggtccag cttctgcacc tcgggctcac cggccatcgc cagggccttc tcgggccggc
    16441 tcaggccgcg ctcgcagtcg gccatcacgg gccacagctc cacgctgccg gtcatccgcc
    16501 gtgccgcacg gaactccgcc agcgcctcgc cgtacttccc gacggcgtac gcggcgaagc
    16561 cggctgcctc gcgaacggcg gggacacgcg acgcgagccg cagcgccaca cgggagaacc
    16621 cgtacgcctg ctccgggtcc tcgtcgagca gcttggccac catgaccagg ttcctggcga
    16681 cgtcgtcggc gagggtcttc ggcaggctca gcagctcctg ccgtacgtcc ttgtcgatct
    16741 cctcgcccgt gacgtcgtcc gggatcggca gccgcttgat cggctcccgg tcgcgccggt
    16801 cgtcacggcg gtcgtcacgg cggtcgtcgt gccggaaccc accgcggtca ccgcggtcgt
    16861 cacggccacg cccggcgccg tacggacgcc gcccgccccg gtcgtcgtcc ctgcggaagc
    16921 cgccacggtc gccaccgcga tcgtcacggc ggtcatcacg gcggaagccg ccgcggtcgt
    16981 cgtcgcggcg cgggccacgg tcgtcacggc ggaagccacc gccacggtcg tcacggccgc
    17041 cgccgtagcc gccaccggag gggcgaccgc cacggtcatc gtcccgacgg ggaccacgat
    17101 cgtcacggcg gaaaccaccg cggtcatcgt cacggcgcgg accgcgatcg tcacggcgga
    17161 aaccaccgcg gtcgtcatca cggcgcgggc cacggtcatc gcgacggaag ctgccaccac
    17221 ggtcgtcacg gccgccgccg tagccgccac cggagggacg accgccacgg tcatcatcac
    17281 ggcgcgggcc acggtcgtca cggcggaagc tgccaccgcg gtcgtcgtcc cgacggggac
    17341 cacggtcgtc cctgcggaag ccgccacggt catcgtcacg gcggaagccg ccgccacggt
    17401 cgtcccggcg cgggccgccg ccgtagccac caccggaggg gcgaccgcca cggtcatcgt
    17461 cacgacgggg accgcgatcg tcacggcgga aaccgccacg gtcgtcgtcg cggcggaagc
    17521 cgccgccacg gtcgtcccgg cgcgggccgc cgccgtagcc accaccggag gggcgaccgc
    17581 cacggtcatc gtcccgacgc ggaccacggt cgtccctgcg gaagctgccg ccgcggtcgt
    17641 cgtcgcggcg cgggccacgg tcgtcacggc ggaagccacc gccacggtcg tcacggccgc
    17701 cgccgaagcc gccaccggag gggcgaccgc cacggtcatc gtcacggcgc ggaccgcgcg
    17761 gacggtcgtc gcggcggggg ccgcggtcgt cgtcacggcg ggggccgcgg ggcccacggt
    17821 cgtcacgtga atagccggga cggtcgtcac ggcgcgggcc gccgccgtag ccaccaccgg
    17881 agggacggcc accacggtcg tcatcacggc gcgggccacg gtcatcgcga cggaaaccac
    17941 cgccacggtc gtcgcggcgt ccgccgccga agccgccgcc agtgggccgg ccgccccggt
    18001 cgtcccgacg cggggcgcgg tcgtcacgcc ggaaaccgcc gcggtcaccg tcctcgcgcc
    18061 gctgcggccg gcgctccgag cgatcgtcgg aagagttggg ggacatcggc gtgactcctg
    18121 tcttcggtac tgcaaacatt ctcgcgcacc gaccacttcg gcgcgcttcg acaaacaaaa
    18181 aaggaccctc agccccagcg tgaacgctgg gaccaagggt cctccaaaga ttgttcggcg
    18241 gcgtcctact ctcccacagg gtcccccctg cagtaccatc ggcgctgaaa ggcttagctt
    18301 ccgggttcga aatgtaaccg ggcgtttccc taacgcaatg accaccgaaa ccctatcggg
    18361 ttctagcgaa caagcacact tttcaattga tgaaatcaaa cagtggaact tggttcaacc
    18421 gacgttgcga ctgttcgcaa cccgggaacc acacagtgga cgcgagcaac tgaggacaag
    18481 ccctcggcct attagtacca gtcaactcca cccgttaccg ggcttccata tctggcctat
    18541 caacccagtc gtctactggg agccttaacc cctcaaaggg ggtgggagtc ctcatctcga
    18601 agcaggcttc ccgcttagat gctttcagcg gttatccttt ccgaacgtag ccaaccagcc
    18661 atgcccttgg caggacaact ggcacaccag aggttcgtcc g
//
