LOCUS       NZ_LWKZ01000023        22599 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02923 scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_LWKZ01000023
VERSION     NZ_LWKZ01000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02923
  ORGANISM  Streptomyces sp. CB02923
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1243511)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1243511)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905005.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:56:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,128
            CDSs (total)                      :: 8,049
            Genes (coding)                    :: 7,904
            CDSs (with protein)               :: 7,904
            Genes (RNA)                       :: 79
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 32 of 145
            Pseudo Genes (incomplete)         :: 128 of 145
            Pseudo Genes (internal stop)      :: 11 of 145
            Pseudo Genes (multiple problems)  :: 22 of 145
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 915992
            Orig. end                         :: 938591
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWKZ01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22599
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="12"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22599
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22599
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12599](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12599)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(184..195)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    587..607
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(2452..2970)
                     /locus_tag="A6A06_RS22165"
                     /old_locus_tag="A6A06_15335"
     CDS             complement(2452..2970)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980482.1"
                     /locus_tag="A6A06_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15335"
                     /product="hypothetical protein"
                     /protein_id="WP_073762997.1"
                     /transl_table=11
                     /translation="MLEKFRAQARARKGERRAHADYTGGVYGSLLAASVVVGASTLGNF
                     PRVELALLLLATGVAFWLAHVHAQLFGARMAQRSLDKGTVLHVCREEWPIVEAAVPSAV
                     AVLVSPLLNLDVQGAAWLALAVALISQVGWATAAARRAGAHWREVVLTDAVNLVIGLLI
                     VALKFTLKH"
     gene            complement(3677..4438)
                     /locus_tag="A6A06_RS22175"
                     /old_locus_tag="A6A06_15340"
     CDS             complement(3677..4438)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS22175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_15340"
                     /product="hypothetical protein"
                     /protein_id="WP_199931060.1"
                     /transl_table=11
                     /translation="MATSRWARRRTRRALRHACRFDIRLPSLHDGIAFAARISVMEVSE
                     PPYPHPVEETASKVRQVLRKAATEFARTCDPADPASAHDALGAHLGYQRSLPSSPPVVF
                     EAALTLDLLPDDRSAVAALLAAQRKQTVADVLRRQKIEALARELTNPAAVLARWIEQDH
                     ADWAQPPCEDAVRTIAQSFAQYRPAHERTAEFEALELIRDFLDSFPDLSQKQMLYALLA
                     GGMHHTNRPEHAAKAAALLDGRTPPAPDGEA"
     gene            complement(4442..6430)
                     /locus_tag="A6A06_RS22180"
                     /old_locus_tag="A6A06_15345"
     CDS             complement(4442..6430)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS22180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_15345"
                     /product="hypothetical protein"
                     /protein_id="WP_199931061.1"
                     /transl_table=11
                     /translation="MEGNERSTIIVTAGSVTMTGKQLLPVTPISDADRHVVRTAWVSIG
                     SRGEPVTAVTAAAALLTGEGPALAVVAGPPGYGKRTAGVRALWEAARAQQGAEGQMPAL
                     QEVRPDWDNPEAPDTSVLPEDPGTGYLLDVAAEIGSWKDPVKVATALVAYAETLRRKRS
                     FMLVVSDERGWPEGTSGTLALVVARATVRPDAHRVAIAHLEHVHYKRDRLAWLRTSGAE
                     PTGTASHLLSRSSSPGEAVRLAAKLAAAEYSPQGLKDAVSEFQEWHDEIKNVFDKTQDK
                     ADDRALLIASVFLSGEDALTVQSAARKLLGEGAEQKVRTILTGPDLTARFESVNARVKE
                     RRATLEDKPGYARAVLLHLWQQRPDIHQPLLAWLSDLTSPQQPGAKRLGPISDLLVELA
                     KAQNDIRVIDKIRDWIDHGDAAEHLKLIARVLATAAEADALGPTVRARLLKWAQAPATS
                     VAKTVALVCQTTFADRYPHQALVRLRHILGRTDRDTAVTAAEEALRAMAGQDHQLPLVW
                     DTISKWAVEPRHLAGHRAFLSLLDPSAGPFALRVMLAAAEKQTEVKEALIQGWSAVLSD
                     ERVNPEAGDLLIAWAHARVNDDLVSADLVTDILRQVVGRHLMSTPISALVFGEPDVRYD
                     AAVIDLRKELQPPPTDVLPAAGSPWGL"
     gene            complement(6526..6885)
                     /locus_tag="A6A06_RS22185"
                     /old_locus_tag="A6A06_15350"
     CDS             complement(6526..6885)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS22185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_15350"
                     /product="hypothetical protein"
                     /protein_id="WP_073763001.1"
                     /transl_table=11
                     /translation="MSFRAGVARFFGRGGEERAQQELGLVDAAHVRLTECPEGERDAVS
                     EALRQQLFIQLAAFLQHHREAAAELRALVDGADSTEEGHRVQANVQHNTNSQVVISGGP
                     LSANSITYRTTGDDK"
     gene            complement(6886..7092)
                     /locus_tag="A6A06_RS41920"
     CDS             complement(6886..7092)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS41920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199931062.1"
                     /transl_table=11
                     /translation="MSAYRNGRLCVAQAFSIAAIDIAPHSELSNMPMSQSLLGGLIMGD
                     ALDVMQVAMGGAAVLVAEMAKSG"
     misc_feature    7046..7057
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.58"
                     /tool="antismash"
     gene            complement(8071..9852)
                     /locus_tag="A6A06_RS22190"
                     /old_locus_tag="A6A06_15355"
     CDS             complement(8071..9852)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986676.1"
                     /locus_tag="A6A06_RS22190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15355"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242440870.1"
                     /transl_table=11
                     /translation="MLAGVALGLLGSLLGLAQPMAAKQVMDTIGQGRPATSPVVILSTL
                     VMAGGLLAGLGHYVLDCSAESIVCTARRRLAHLLPRLRVPVLENTEPGDLIARVTSDTA
                     LLRRAAPQAVSAAVTGTLITTATVVMMGVLDAVLLGVTLIVIAFVGLVVLVVSPHIGRA
                     TRHTQEAVGRLGAGLERTLGALRTVKAAGAEHRETAALHHAAEYARRTGVRAAAWEAVS
                     ATLSAVVLQVCFLVVLGVGGARVASGAIGVSTLVAFLLYLFALTPRIGQLVEGVGQLQI
                     GAAAAVRIREAETLEAEEAGPAEAGSAPPEGAERRGDEAAAAPRRSPAPHARRAHPAAV
                     AFEHVRFTYRPGLPPAHQHVSFALPAGGMTALVGPSGAGKTTVLALIERFYEPDAGRVL
                     LDGRDVRQWPLGELRAAIGYVEQDTPVLAGTLRDNLTLGTADVTDEQVARVLRLARLDT
                     ATDRLPHGLDTQVGHRGSRLSGGERQRVAIARALLRRPRLLLLDEATSQLDASNEAALR
                     DTVTDIARRTTVLVVAHRLSTVTTADRILVMEAGRVRALGTHTELLARDSLYAELASTQ
                     LLGPRRRHGPSAPGPEC"
     gene            complement(10001..10417)
                     /locus_tag="A6A06_RS22195"
                     /old_locus_tag="A6A06_15360"
     CDS             complement(10001..10417)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986677.1"
                     /locus_tag="A6A06_RS22195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15360"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_199931063.1"
                     /sec_met_domain="PF13471 (E-value: 3e-25, bitscore: 84.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPEAVPYRPRSIPLTRRFTARVAVGCAHVLATLPPGRIRAVLS
                     RLRRGARPATLAEAARARQTVLAVSLAAGGGKGCLPRSLATVLLCRLHGQWPVWCVGVR
                     ARPPFAAHAWVEAEGELVGENVPASYFQRFFAVE"
     gene            complement(10461..10718)
                     /locus_tag="A6A06_RS22200"
                     /old_locus_tag="A6A06_15365"
     CDS             complement(10461..10718)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986678.1"
                     /locus_tag="A6A06_RS22200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15365"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_073763004.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.3e-22,
                     bitscore: 75.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.3e-14, bitscore: 50.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYALKPGVLLTETEYGMALLDQKSAEYWTLNPTAAVVLQTLLDGH
                     GAGQAVQALTGRYEDVDTDLATQDVTRIIDDLRSAGLITP"
     aSDomain        complement(10467..10718)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A6A06_RS22200_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.80E-24"
                     /identifier="RREFam002.1"
                     /label="A6A06_RS22200"
                     /locus_tag="A6A06_RS22200"
                     /protein_end="84"
                     /protein_start="0"
                     /score="75.5"
                     /tool="antismash"
                     /translation="MYALKPGVLLTETEYGMALLDQKSAEYWTLNPTAAVVLQTLLDGH
                     GAGQAVQALTGRYEDVDTDLATQDVTRIIDDLRSAGLIT"
     gene            complement(10740..12599)
                     /locus_tag="A6A06_RS22205"
                     /old_locus_tag="A6A06_15370"
     CDS             complement(10740..12599)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_053804306.1"
                     /locus_tag="A6A06_RS22205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15370"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_073763005.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-35, bitscore:
                     119.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEETLSLSALPSWFVVLPDTDAATAVAAKALAYASHSLRHASGRP
                     WLVGRWAAETAVVGVHGETRVAAIGEHSVTLREARRAAAAVATTASLTALDRHSTTWAG
                     SFHLMASSGGRVRVQGGVVDLRRVFHADAPSPASGRVSIASDRADVLAELVGAALDERR
                     LALELLTLGVPHPLSGSPQWRGVHVQPGGHHLTLDIDGRARSTRWWSPPVPEVSLAEGA
                     MRLREVLTAAVEVRVRGRDLVTADLGGLDSTAVCCAAAGGDAQVVAYTAALHDELGDDV
                     HWARRTVQALGSVEHHVIPAQDTALTFDGIDTLRDILDTPSMLTVDRNRRMHLVALASA
                     RGSGLHLTGLGGDELLAGTPARLHDLITAHPFVALRDVRGYAAKYQWPRREVLRQLADR
                     RSYRSWLARVARDLTEPAAAADEPLLDWSVPPRMPPWATPEAVVAARELLTACLPDAEP
                     RGRGHGEHRELAAMDGISQWTRHIGQMAAPLGVTVAAPYYDDRVIEACLAVRTPDRITP
                     WRYKPLIVEATRGIVPEAVRTRDTKANATFEEETGLRRHRARLLALCEESRLGRLGLVD
                     VGVLREWCRRSLSAETESYLLHPTVACEVWLRSREMVPAPPGR"
     gene            complement(12750..12857)
                     /locus_tag="A6A06_RS41925"
     CDS             complement(12750..12857)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.3"
                     /locus_tag="A6A06_RS41925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_106970745.1"
                     /transl_table=11
                     /translation="MTYERPTLTKAGGFRKVTGVKNTGPKDVLGGKQLL"
     misc_feature    complement(12964..12984)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     misc_feature    complement(13158..13178)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            complement(13252..13671)
                     /locus_tag="A6A06_RS22210"
                     /old_locus_tag="A6A06_15375"
     CDS             complement(13252..13671)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS22210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_15375"
                     /product="hypothetical protein"
                     /protein_id="WP_073763006.1"
                     /transl_table=11
                     /translation="MLARHATFDGHAAAVHGDTDGMTAGRWGFISKKYTADTTRDLRVL
                     RGVPVLLTLAGHDVHVDTAGTERTYHRILGGGSALTVERYPDATHSLLKRSIEQSDARI
                     TLTGLFSPRSLFAAGFLDNQRQFLNELGRGTGGTS"
     gene            13798..13950
                     /locus_tag="A6A06_RS41930"
     CDS             13798..13950
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS41930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199931064.1"
                     /transl_table=11
                     /translation="MTKLAGVPVPTFGRTQPAWLAPQRGLATRYDKTRESYHAAVTIAS
                     LLLWI"
     misc_feature    complement(14190..14204)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     misc_feature    14191..14205
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.68"
                     /tool="antismash"
     gene            14305..>14568
                     /locus_tag="A6A06_RS42925"
                     /pseudo=""
     CDS             14305..>14568
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379905.1"
                     /locus_tag="A6A06_RS42925"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="glyceraldehyde 3-phosphate dehydrogenase
                     NAD-binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVVRVGINGFGRIGRNCLRCVLERVARQATAVEVVAVNDVASAGT
                     LTHLLEYDSTYGRFGLEVGTEDGALVVAGRRIAVCSEPDPAAL"
     gene            complement(15616..16083)
                     /locus_tag="A6A06_RS22230"
                     /old_locus_tag="A6A06_15390"
     CDS             complement(15616..16083)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047755.1"
                     /locus_tag="A6A06_RS22230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15390"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_073763009.1"
                     /transl_table=11
                     /translation="MSSTPSSEQPPDDPALDQIGPALSRLRRRAPASSKDLSRNLVLNV
                     IADAPGETTVGGLAAEMGVAQPVASRTVAACIADGLLRRAASQSDGRRTVLELTDHGEA
                     ERNRFAAEQREAFLEITVAWSPEERTQFARLLTRYGADATAWSRKQTTSRD"
     misc_feature    16130..16150
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 23.43"
                     /tool="antismash"
     gene            16187..17401
                     /locus_tag="A6A06_RS22235"
                     /old_locus_tag="A6A06_15395"
     CDS             16187..17401
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047754.1"
                     /locus_tag="A6A06_RS22235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15395"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_073763010.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4e-23, bitscore:
                     78.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTAITNAQIFDGEKVVGVRTVVIDGGRIARIGGDAPEGSEIVD
                     GSGATLLPGLIDAHVHSAPGSLALALRFGVTTELEMQGMNTRENRGAITDDDTQADVRS
                     SGFAITPPGGHPSELMPEGFRPKWDLPPVMPLMPFSTTPEEAAAFVPQLLARGSDFIKF
                     MIDDGSVEGHPGLPALDQATVNAGVAEAKKYGALTVAHALTVEATRTAAEAGVDGVTHV
                     FMDQPHTAEIISLIKDAGMFVIPCVTLNASMMGVTGSELADDPRVAARLDAGWDRTLRS
                     SYNRYPQGKLHDVYDTVRALDAAGVDVLAGTDVSMPETFFGGLAHGASLHHELQYLVQA
                     GLTPARALRAATATTARRFRLSDRGRIAEGLRADLLLVDGDPVSNISDTLNTRAIWRRG
                     TRLAA"
     gene            complement(17936..18967)
                     /gene="dmpG"
                     /locus_tag="A6A06_RS22245"
                     /old_locus_tag="A6A06_15405"
     CDS             complement(17936..18967)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523023.1"
                     /locus_tag="A6A06_RS22245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15405"
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_073763012.1"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-63, bitscore:
                     210.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPNQPPALYIQDVTLRDGMHAVRHLYTVDQARTIAAALDAAGVG
                     AIEIAHGDGLSGSSITYGVGAHTDWEWIEAVCDSVHHALPTTLLLPGIGTLHDLRQAHA
                     LGIRSVRVATHCTEADISAQHIGAARDLGMDVAGFLMMSHMAEPGELARQAKLMESYGA
                     GCVYVTDSGGRLTMDGVRDRVRAYRDVLEPDTGIGIHAHHNLGLGVANSVVAVENGVTR
                     VDASLAGQGAGAGNCPLEAFVAVADLMGWEHGCDLFPLMDAADDVVRPLQDREVRVDRE
                     TLTLGYAGVYSSFLRHAEAAARRHGLDTRAILVEVGRRKMVGGQEDMITDIALDLAAAD
                     SAG"
     gene            complement(18964..19914)
                     /locus_tag="A6A06_RS22250"
                     /old_locus_tag="A6A06_15410"
     CDS             complement(18964..19914)
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0008774 - acetaldehyde dehydrogenase
                     (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552483.1"
                     /locus_tag="A6A06_RS22250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15410"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_073763013.1"
                     /transl_table=11
                     /translation="MSTKVAVIGSGNIGTDLMIKILRLSDSLEIAAMVGIDPDSDGLAR
                     ARRLKVATTHEGVDGLVRLDEFADVEIVFDATSAGAHRHHDEVLRSLGRRVVDLTPAAL
                     GPYVVPPVNGDAHLDAPNVNMVTCGGQATIPIVAAVGAVTPVHYGEIVASISSRSAGPG
                     TRANIDEFTETTSSAIEKVGGAVRGKAIIVLNPAEPPLIMRDTVYCLVSECDDAAVTAS
                     VEEMVARVQAYVPGYRLKQKVQFERVADDDPLRTLLPVGTKTTGAAKVSVFLEVEGAAH
                     YLPAYAGNLDIMTSAALRTAERMSAAQPFTEVVSR"
     gene            complement(19911..20768)
                     /gene="mhpD"
                     /locus_tag="A6A06_RS22255"
                     /old_locus_tag="A6A06_15415"
     CDS             complement(19911..20768)
                     /EC_number="4.2.1.80"
                     /GO_function="GO:0008684 - 2-oxopent-4-enoate hydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019439 - aromatic compound catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="mhpD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552484.1"
                     /locus_tag="A6A06_RS22255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15415"
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="WP_073763014.1"
                     /transl_table=11
                     /translation="MFAPHHFPPGAIVSAHEPADAVHKAAAALEEAARTGAPCAPVRSR
                     LPEGDVEAAYAVQRLHVERGIAAGRRLVGRKIGLTSPAVQRQLGVDRPDFGALFADMAV
                     PEGRPIAPGRLLQPKVEAEVALVLGADLPHHDPTVADLLRATAFALPALEIVDSRIADW
                     DITIVDTIADNASCGLYVLGGTPAPLDRVDLRAVTMILTKNGETVSEGTGADCLGSPLT
                     AALWLASTLAGLGDPLRAGDIVLTGALGPMAAAAEGDEFTAHIEGLGTVTTTFASAATE
                     RTAA"
     gene            complement(20881..21900)
                     /locus_tag="A6A06_RS22260"
                     /old_locus_tag="A6A06_15420"
     CDS             complement(20881..21900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523019.1"
                     /locus_tag="A6A06_RS22260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_15420"
                     /product="VOC family protein"
                     /protein_id="WP_073763015.1"
                     /transl_table=11
                     /translation="MNTAATSTASVFGAVHLGYIVIETNRFADWRRFGTDAIGMHHDSL
                     SRDLMRFRLDDQECRFLLRRGPAEDVVATGWHIDDHASFEQIEARIRAHGVPVVRGPDE
                     EAALRGVERLLRFPGPKGITQEIYTTPLTSAEPLRMLASGFVTGDSGMGHVALTSTRPT
                     QIRGYFNTVFDARLTDYIDETISGVKLKIRFLRVNERHHSIAVAATRGLPIDPIRTRVQ
                     HLNIQAATLDDVAQSYQRVHELGFDMALSVGRHTNDKELSYYARTPSGFEWEVGWNPIV
                     IDETIWEPSTHQGISVWGHLPVGQTIVDKLAQFRAGARSLAHPENTVPALSGAGIADD"
     misc_feature    complement(22381..22396)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.43"
                     /tool="antismash"
     misc_feature    complement(22516..22530)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 gtggtcgtcg gcgacatcgt gctcctctcg gccggaaacg aggtcccggc ggacggccgc
       61 atcatcacgg ccagcgctct gcagatcgac gaggcgacac tgaccggcga gagcgcaccc
      121 gtcgccaagg aagcgcggac gttgtccggc gaacggccgg gaccagccga tcagtcgaac
      181 atggcgttca tgaacacccc tgtcacgcac ggcagcggca tcgtcatcat cacggccacc
      241 ggggccgaca ccgaactcgg caccatttcc ggcatgctct ccgccacgcc ccaagaggtc
      301 tcgccgctga ccaaggagct ggaccggctc accctgtgga tcgcggcggc ggccggtctg
      361 acgatgatcg cgatgttcgc cctggggcgc agccgcggcg aagcctggga cgtgctcttc
      421 gtgagcgccg tcgccctggc catcgcggcc atcccggagg cactgcccac ggtggcgcag
      481 accatcctct cgatcggggc cgtcaacctc gccagggggc acgcgatcgt gaagggcctg
      541 ccgtcggtgg aaaccctggg cttcacctcg gccctcaact ccgacaagac cggcaccttg
      601 acgatgaatc aggtgacggc cgtagaggtg ctgacgccga cggaccgcta caccgtctcc
      661 ggcagcggtt acggcctgga aggcaaggtg catcacgccg cgggcagttc ggcctccatc
      721 gagcaggcgg tgctgccgta tctggtcgcc tccgacgccg cactcgtcga cggcaaggtg
      781 gtcggagatc ctacggaggg cgcactggtc gtcctctgcc acaaggcggg cctggacatc
      841 gacgccaccc gcgagcgcct gccccggctg gccactctgc cgttcgatcc gacctacaag
      901 ctgatggcca cgttcaacgc ggcgagcgat gccgccgggc ggccggtcgt acggtgcttc
      961 gtgaagggtg cggcaccggc ggtgacggcc cgtgcggcaa cggcgctctc cgaccgcatg
     1021 agcttcccgt gggacgccga cctgcgccgg cgggcacagg cgcacgagga ccggatggca
     1081 cggcagggca agcgggtgat ggccgccgcg gtccgcgacc tggacccgga acggttcgac
     1141 ccggccggcg acctcctcgg gtacgtcacc gaactgcaga tgacgagcct ggtggggatg
     1201 gtcgatccgc cacgggccca gtcccgggcc gcggtcgccg ccgcgcaggc agcccggatc
     1261 cgcgtccgca tggtcaccgg ggacgaggtc accaccggcg ccgccatcgc cgaacagctc
     1321 ggcatcgagg gcgacgccgt cctcggggcg gacttcgccg ccctgtccga gcccgaacgg
     1381 ctggccgcca tcgagcacat cggggtactc ggccgggtcg ctcccgaaca caaggtgctg
     1441 ctcgcggaca ccttgaagaa gaagggcgac gtggtggcca tgacggggga cggcgtcaac
     1501 gacgccccgg cgatcaaagc ggccgacgtc ggcatcgcca tgggctccgg cacggaagtc
     1561 gccaagaacg ccagccagat gatcctctcc gacgacaact tcgccagcat cgtctccgcg
     1621 gtcgagcagg gccggaagat ctacgacaac ctcaccaagt acatccgctt cgtcctggtc
     1681 ctgctggtgg tcttcgtcct gacgttcctc ggcgccgcgc tgttcaacat cgccgccggt
     1741 gaaccgttca ccgccgcgca ggtcctgtgg atccacttct tcgtcaacgc cgctttcgga
     1801 ttcgccctcg gcttcgaccg ggagagcccg ggtctcatgg cccgcaagcc gcggccccgc
     1861 ggcgagccgg tgctcaccac gggagtgatg atcaccgtcg gatcggcggg actcgccatc
     1921 agcgtcggcc tgctctgcat gatccagctc ggtcagtcgc tcttcgacag ccttcccatc
     1981 ggcaattcca tcgcgttcac ggccttcgcc ctgtgcctga tcgtggccgc actcgaatgc
     2041 cgcaacgaga ccggtaccgc gctgacgacc gccagcttcg acagcaagca gatgaaccgg
     2101 gcgatgctca tcgaggtcgt cctcgccgtc gcggtcacac agatggacct cttccaccgt
     2161 ctgctgggca ccaccgaact cgacctgagg catttcgcat gggccctcgt acccgccgcc
     2221 gcactgctgc tcctgtggga actcggcaag ctcatcgccc gcggccgcgt acatgcccgg
     2281 tgacggggcg aatgccggat gccgggtgcc gtgcgccatg agggcctcat gcccccgcac
     2341 ccggcatacg gcagtgcgac cagttcatcg aggtgacgca gacgtattgc cgcgcccatc
     2401 gcgtcaagcg gcgctggcga ggtaatccgg ccctcaacga cgtgccccgg atcagtgctt
     2461 cagcgtgaac ttgagggcga cgatcagcag accgatcacg aggttgaccg cgtcggtgag
     2521 gaccacttcg cgccagtggg cgcctgcgcg ccgagcggcg gcggtggccc agcccacctg
     2581 gctgatcaga gcgacggcga gggcgagcca ggccgcgccc tggacatcga ggttcagcag
     2641 ggggctgacg agcacggcga ccgcggaagg cacggcggcc tccacgatgg gccactcctc
     2701 acggcacacg tgcagcacgg ttcctttgtc cagggagcgc tgcgccatgc gtgcgccgaa
     2761 gagctgggca tggacgtgcg cgagccagaa ggcgaccccg gtggcgagca gcagcagcgc
     2821 cagctccacc ctcggaaagt ttccgagcgt actggctccg accacgacgg aggcggcgag
     2881 cagcgaaccg tagaccccac cggtgtagtc ggcatgagcg cggcgctcac ctttccgtgc
     2941 ccgagcctgc gccctgaact tctccagcat ccttcgctcc cgaggtcgtc cgtgacttgt
     3001 ccggaagagc tggtcaggag gggtgtagcg gaggtacgac atctccggcc cccgcgctga
     3061 gcgggccgga gggaaggcgc ctgacgggtg gaggaacaga agtcgggcgc cttctggtgg
     3121 gacgttagaa gaagcccagc ttcttcggcg agtacgatac cagcaggttc ttcgtctgct
     3181 ggtggtacaa ggctcattgt ggtgctgacc tgctgtgatg ctggctgccg ccgcagttgg
     3241 gggagtactg gtccgtgtat ggtccggatc ttggcctcag ccgacgggag ctcgtgacag
     3301 acggctcaat agtcttggcg tgtgtgtagc gcccgggtcg ctggacgttg ccgacgctgt
     3361 ttgagtggcg aaaatggaga agggccttga gatatcgggc gtttcccaga cggacgtcgt
     3421 acggatcgga gatcaggctt cggtgtccgg ccgcctgcct atgcagcctg ggtggtggcc
     3481 ctgccggcgg aagggggctt cgtcgggatg caggcggact cggatgtgcc gccaggcggc
     3541 gtcgaaggag aggctgccgc ggctggctcg cgccaggcgc caggcgtacc agctggtacg
     3601 gggcgacagt agccaacgca gcgcgctcga actcatcgaa cgtcccagcg ggttgtttca
     3661 cggctcgggc ggtggttcac gcttcgccat ccggtgcggg cggggtgcgg ccgtcgagta
     3721 gagcggcggc cttcgccgcg tgttcggggc ggttggtgtg gtgcatgccg cctgccagga
     3781 gcgcgtagag catctgcttc tgagacagat cgggaaaact gtccaggaaa tccctgatca
     3841 gttcgagtgc ctcgaactcg gcggtccgtt cgtgtgcggg acggtactgg gcgaaggact
     3901 gcgcgatggt acgcacggcg tcctcacacg gtggctgtgc ccagtcggcg tggtcctgct
     3961 cgatccaccg tgccaggacg gccgctgggt tggtgagttc cctggccagc gcctcaatct
     4021 tctgtcggcg caggacatcg gcaaccgttt gtttgcgctg tgcggcgagc agtgccgcca
     4081 cggcggaccg gtcgtcgggc aggagatcca gcgtgagcgc ggcttcgaag acaacgggtg
     4141 gactgctggg cagggagcgt tgatagccca gatgcgcacc gagtgcatca tgcgcggaag
     4201 cggggtcggc agggtcgcag gtacgggcga actcggtggc cgccttgcgc agcacctggc
     4261 gtaccttcga ggcggtctcc tcgacagggt gcggatatgg aggctcgctc acctccatga
     4321 cggagatccg cgcggcgaag gcgatgccgt catggaggct gggcaggcgt atgtcgaagc
     4381 ggcaggcgtg ccgcagtgct ctacgggtac gacggcgcgc ccaacgactg gtggccacgg
     4441 atcaaagccc ccacggtgag ccggctgcgg gcaacacgtc cgttgggggg ggctgaagct
     4501 ccttgcgcaa gtcgatgacg gccgcgtcgt agcggacgtc cggctcgccg aacacgaggg
     4561 cggagatcgg cgtggacatc aggtgccgcc cgacgacttg gcgcaggatg tccgtgacca
     4621 ggtcggcgga taccaagtcg tcattcaccc gggcgtgggc ccaggcaatg agcagatccc
     4681 cagcctcagg attgacccgc tcgtccgaca gcactgcgct ccagccctgg atcagagctt
     4741 ccttgacctc tgtctgtttt tcggcggccg ccagcatcac ccggagcgcg aaggggccgg
     4801 cgctcgggtc gaggagggag aggaaggcgc ggtggccggc cagatggcgg ggctcgacgg
     4861 cccacttgct gatcgtgtcc cacaccaggg ggagctggtg gtcctggccg gccattgcac
     4921 gcagggcctc ttcggctgcg gtgacagcgg tgtcccgatc ggtgcgcccc aggatgtggc
     4981 gcaggcgtac gagtgcctga tgggggtagc ggtcggcgaa cgtggtctgg cagacgagag
     5041 caacggtctt ggccacggac gtggcggggg cctgagccca cttcaggagc cgggcccgca
     5101 cggtggggcc gagggcgtcc gcctctgcgg cggtggccag gacacgtgcg atcagtttca
     5161 ggtgctcggc ggcgtcgccg tggtcgatcc agtcgcggat cttgtcgatg acccggatgt
     5221 cgttctgtgc cttggccaat tcgaccaaca gatcactgat cggtccgagg cgcttggcgc
     5281 ctggttgctg cggtgatgtc aggtcgctga gccatgccag aagaggttgg tggatgtcgg
     5341 ggcgctgctg ccacaggtgc agcagcacag ctcgcgcgta ccctggcttg tcttcgaggg
     5401 tggcgcggcg ctccttgacg cgcgcgttga cgctctcgaa ccgggccgtc aggtccggcc
     5461 cggtcaggat ggtgcgtacc ttctgctccg cgccttcgcc caacaacttg cgggccgcgc
     5521 tttgaacagt gagggcgtcc tcgccgctga ggaaaacgga cgcgatcagc agagcccggt
     5581 cgtcagcctt gtcctgggtc ttgtcgaata cattcttgat ctcgtcgtgc cattcctgga
     5641 actcggatac agcgtccttc aggccctgtg gcgagtactc cgcggcggcc agcttggccg
     5701 ccagccgaac agcttcgccc ggactgctgc tccgggacag caggtgggaa gccgtaccgg
     5761 tcggctccgc gccgctggtg cggagccaag cgagccggtc gcgcttgtag tggacgtgtt
     5821 ccaggtgcgc gatggctacc cggtgggcgt ccggccggac cgttgcccgc gcgaccacga
     5881 gcgccaaagt gcccgaggtg ccctccggcc agcctcgttc atcggagacg acgagcatga
     5941 acgacctctt gcggcgcagc gtctctgcgt acgccaccaa agccgttgcc accttgaccg
     6001 ggtccttcca cgagccgatc tctgccgcga cgtccagcag gtagccggtg ccggggtcct
     6061 cggggagcac ggaggtgtcc ggggcctcgg ggttgtccca gtcgggccgg acctcctgca
     6121 gcgcgggcat ctgaccttcg gccccctgct gggcccgcgc cgcctcccac agtgctctga
     6181 ctcccgcggt gcgcttgccg taaccaggtg ggccggcgac caccgcgagc gccggtccct
     6241 cgccggtgag cagcgctgcg gcggctgtca cggcggtgac gggctcgcct cgggacccga
     6301 tgctcaccca cgccgtgcgc accacatgac ggtcggcgtc ggagatgggc gtgacaggca
     6361 gcaattgctt cccggtcatc gtcaccgatc ccgccgtgac gatgatcgtg gagcgctcgt
     6421 tgccctccac attcaccttc atggtcccgg ctgcggccgc ggatggtgtt cctggtggaa
     6481 cgggaggtac gggcggaacg ccgtcaggga ctgtgtcctc actactcact tgtcatcacc
     6541 agtagtccgg taggtgatgc tgttggcgct cagcggaccg ccggagatga cgacttggct
     6601 gttggtgttg tgctgcacat tggcctggac ccggtgaccc tcctcagtcg aatccgcccc
     6661 gtccaccaga gcccggagct cggccgccgc ctcgcgatga tgctgcaaga acgccgcgag
     6721 ctggatgaac agttgctgcc gcagcgcctc ggacacggcg tcgcgctcgc cctccggaca
     6781 ttccgtcagc cggacatgcg cagcgtcgac gaggcccagt tcctgctgag ccctctcctc
     6841 gccaccccgc ccgaagaacc gcgccacccc cgcgcggaac gacactcagc cgctcttggc
     6901 catctctgcg acaagcacgg ccgccccacc catggcgacc tgcatgacgt ccagcgcatc
     6961 ccccatgatc agccccccca gaagtgattg agacatcggc atattcgaca gctcagagtg
     7021 cggggctata tcgatcgcag caattgaaaa cgcttgcgcc acacacaagc ggccattccg
     7081 gtacgcgctc atttcggcat gacgcgacga aggtgaatgc cagcggaaac ggcatggatc
     7141 aagggatgcc cagggagagt cactggtcgg atgaatccag tcagctgaaa ccggccgtga
     7201 gcgggtaaca agtgccaccg gaaggaggcg gaaaactgct ggcagcagca gcggagggca
     7261 gtgctgcagg gcacatcaac agcgggcggc gcacggctct tcggccccat cgaccggagc
     7321 gctggcgacg agtcgtgttg cttccgcaag gacccgggcc cgggatgatt gtgaaaggat
     7381 atcgcctgcc cgaagggccc ttcgtacgcc gtctggccgt gcctgtggcc tgacggcggt
     7441 ccggatgtcc cacggcctcg tccatgccgc cggcgcggtg ccggcctcca gccggtcatg
     7501 gcgcatcgcc tgtccgtggc tgacgaggac ggagagttcg gcggcccgct cctggaagcg
     7561 ccctggaacg agcgcgccca gcagcggggc gaggacggcg gtgactagcg tggtcaacac
     7621 ggaagaacct ctggctgcat gacttttaca acgggcggcg aagcgctcgt cgggtgtcct
     7681 cgccgtgagc ggccgcagtg ggagcctgct cactggccag gggcgcggat gcgccttgcg
     7741 aactcgcggc gagccttggg ccggtccggg accacggtgg cgcccggggc gcagtcgagg
     7801 gactggcaga tgtcgaggag tcggcggtga actgcgggca cggtggaggg ggcggggcgc
     7861 agccccggcc acgtcgtatg ttccgcagcc acaaggttcc ggcttggcgg cgcggcgccg
     7921 tccagcattc gccttgcccg ttggtgggga gccggacgac ggggaagagg gcagaacgcc
     7981 gaggtatggg caggccgggc cggtcgtcac tggagtctgg ccgccatcgg cccgagcccg
     8041 ctgtacctcg ttcgtccttc ccgggaaagg tcagcattcc ggccccgggg ccgaggggcc
     8101 gtgccttcgc ctggggccga gcagttgggt gcttgccaat tcggcgtaca gggagtcacg
     8161 tgccagcagt tcggtgtggg ttcccagcgc ccgtactcgc ccggcttcca tgaccaggat
     8221 gcggtcggcg gtggtcacgg tggacagacg gtgcgcgacg accaggacgg tggtgcggcg
     8281 cgcgatgtcc gtgacagtgt cgcgcagggc cgcctcgttg gacgcgtcga gttgagaggt
     8341 ggcctcgtcc agcaggagca gccggggccg gcggagcagg gcccgggcga tcgccacccg
     8401 ttgccgctca ccgccggaga gccggctgcc gcggtggccg acttgggtgt ccagaccgtg
     8461 cggcaggcgg tccgtcgcgg tgtcgagccg ggccaggcgc agcacccggg cgacctgttc
     8521 gtcggtgacg tcggctgtgc ccagcgtcag gttgtcgcgc agggtgccgg cgagtacggg
     8581 cgtgtcctgt tcgacgtagc cgattgcggc gcggagttca ccgaggggcc actggcgcac
     8641 gtccctgccg tccagcagta cgcgtccggc gtccggctcg tagaaacgct cgatgagggc
     8701 gagaacggtg gtcttgcccg caccggacgg cccgacgagc gcagtcatgc ctccggcggg
     8761 aagtgcgaag gagacgtgct ggtgggccgg cgggagacct gggcggtacg tgaagcgcac
     8821 gtgctcgaag gccacggcgg cggggtgtgc gcgccgtgca tgcggggccg gggaccgccg
     8881 cggagccgcg gccgcctcgt cgccgcgtcg ttccgcaccc tccggtggcg cggaccctgc
     8941 ttccgcaggc cctgcttcct cggcttccag cgtctcggct tcccggatgc gcaccgcggc
     9001 ggccgccccg atctgcagct ggcccacccc ttcgaccagt tggccgatcc ggggggtgag
     9061 ggcgaagagg taaaggagga aggcgacgag cgtggagacg ccgatggcgc cggaggcgac
     9121 gcgtgcgccg cccactccga ggacgaccag gaaacagacc tggaggacga cggccgacag
     9181 ggtggcggag accgcctccc acgcggcggc gcgcacgccc gtgcggcggg cgtactcggc
     9241 cgcatggtgc agtgcggcgg tctcccgatg ctcggcgccc gccgctttga cggtgcgcag
     9301 ggcacccagg gtccgttcga gcccggcccc cagccggccg acggcttcct gcgtgtgccg
     9361 ggtggcccgg ccgatgtgcg gggacaccac gaggacgacg aggccgacga acgcgatcac
     9421 gatgagggtg acgccgagca ggacggcgtc cagcactccc atcatcacga cggtcgctgt
     9481 ggtgatcaga gtgccggtga ccgcggccga cacggcctgg ggggcggcgc gccgcagcaa
     9541 cgcggtgtcg gaggtgacac gggcgatcag gtctcccggc tcggtgttct cgagtaccgg
     9601 cacgcgcagg cgcggaagaa ggtgggccag tcggcggcgg gcggtgcaga cgatggactc
     9661 ggcggagcag tcgagcacgt agtggccgag gcccgcgaga agtccgccgg ccatcaccag
     9721 cgtgctgagg atcaccacgg ggctggtggc cggccgccct tggccgatgg tgtccatcac
     9781 ctgtttggcc gccatcggct gggccagccc caggaggctg cccagcaggc cgagcgcgac
     9841 accggcgagc atgcgcccgc gttgcggtcg gaggtggccg gcgagagccc ggaggccgga
     9901 ccacgcgggg ccggggccgg ggaggccgcc cggtcgttcc ggtgggtgcg cctgtccgcc
     9961 ggtgcggcgc gtctcgacgg ggggtgctga ggtcacggcc tcactccacg gcgaagaagc
    10021 gctggaagta ggaagccggt acgttctcac cgacgagttc gccctcggcc tccacccagg
    10081 cgtgcgcggc gaacggagga cgcgcgcgga ctcccacgca ccagacgggc cactgcccgt
    10141 gcaagcggca cagcagcacc gtggccaggg accggggcag acatcctttg ccgcctccgg
    10201 cggccaggct cacggcgagc accgtttgcc gggcacgtgc cgcctcggcg agcgtggcgg
    10261 gccgcgcccc gcgccgcagc cggctcagga cggcgcggat gcggccgggt ggcagggtgg
    10321 ccagtacgtg ggcgcagccc accgccactc gggccgtgaa gcggcgggtc aggggaatgg
    10381 agcgcgggcg gtaggggacc gcttccggtg ccgacattgc gtacctcttc cctgggccgg
    10441 gtgcgcgccc ggtgcggcgc ttacggtgtg atgaggcccg cggagcgcag gtcgtcgatg
    10501 atgcgagtga cgtcctgggt ggccagatcg gtgtcgacgt cctcgtaacg cccggtcagc
    10561 gcctgcaccg cctggccggc gccgtggccg tccagcagcg tctggaggac gacggccgct
    10621 gtggggttga gggtccagta ctcggcgctc ttctggtcga gcagcgccat gccgtattcg
    10681 gtctcggtca gcagaacacc gggcttcagc gcgtacatcg ccttcacctt tccgttcggt
    10741 cagcggccgg gcggtgccgg taccatctcg cgggaacgca gccacacttc gcaggccacg
    10801 gttgggtgca gcagatagct ctccgtctcc gcggacagcg agcggcggca ccattcccgc
    10861 aggacgccca cgtcgaccag gccgagccgc cccagccggg attcctcgca gagcgccagc
    10921 agccgggcac ggtggcgccg cagcccggtc tcttcctcga acgtggcgtt ggccttggtg
    10981 tcgcgtgtgc ggacagcttc gggcacgatg ccgcgcgtgg cctcgacgat caggggtttg
    11041 tagcgccacg gggtgatccg gtccggtgtc cggaccgcga ggcacgcttc gatgacgcgg
    11101 tcgtcgtagt acggggcggc cacggtgacc cccagaggcg cggccatctg tccgatgtgc
    11161 cgggtccact gggaaatccc gtccatggcg gccagctccc ggtgttcgcc gtgtcccctg
    11221 ccccgtggct cggcgtccgg caggcaggca gtcagcagct cgcgcgccgc cacgacggcc
    11281 tcgggcgtgg cccagggcgg catacgggga ggtacggacc agtcgagcag cggctcgtcc
    11341 gcggcggcgg ccggctcggt caggtcccgg gcgacccggg cgagccagga ccggtaggag
    11401 cggcggtccg cgagttggcg cagcacctcc cgccggggcc actggtactt ggcggcgtac
    11461 ccgcgcacgt cccgcagggc gacgaagggg tgggcggtga tcaggtcgtg cagccgggcg
    11521 ggcgtaccgg ccaggagttc gtcgcctccc agcccggtca ggtgcaggcc agagccccgt
    11581 gcgctggcca gggccacgag gtgcatgcgg cggttacggt cgaccgtgag catgctgggc
    11641 gtatccagga tgtcccggag cgtgtcgata ccgtcgaagg tcagggccgt gtcctgggcg
    11701 ggtatgacgt gatgctcgac ggaccccagg gcctggacgg tccgccgcgc ccagtgcacg
    11761 tcgtcaccga gttcgtcgtg gagggccgcg gtgtaagcga cgacctgcgc gtccccgcct
    11821 gccgccgcgc agcacacggc ggtcgaatcc aacccgccca ggtccgccgt caccaggtcg
    11881 cgtccccgca cgcgcacctc gacggcggcg gtcagcacct cgcgcaggcg catggctccc
    11941 tccgccaggg agacttcggg gacgggcggt gaccaccacc gggtcgaccg ggcccgaccg
    12001 tcgatgtcga gagtcaggtg gtgaccaccg ggctggacgt ggaccccccg ccactgcggt
    12061 gatccggaca aggggtgggg cacgcccagg gtgagcagct ccagggcgag ccggcgttcg
    12121 tccagcgccg caccgaccaa ctcggccagc acgtcggccc ggtcggaggc gatgctcacc
    12181 cggccggacg ccggggaggg ggcatcggcg tggaacaccc gccgcaggtc gacgacgccg
    12241 ccctgcaccc ggacccggcc gcccgagctg gccatgaggt ggaagctgcc ggcccaggtg
    12301 gtgctgtgcc ggtccagcgc cgtcaacgag gccgtggtgg ccaccgcggc ggcggcgcgc
    12361 cgcgcttccc ggagggtgac ggagtgttcc ccgatcgcgg cgacgcgggt ctcgccgtgc
    12421 actccgacga cggccgtctc cgccgcccac cggcccacca gccagggcct gccggacgca
    12481 tgacgcaggc tgtgcgacgc gtaggcaagt gccttcgcgg cgaccgccgt ggccgcgtcg
    12541 gtgtcgggca ggacgacgaa ccagctgggc agggccgaca gggacagagt ctcttccaca
    12601 gctacggcct tcggtcggtg gggctccgga cgtcggaagg ggcggggcgc gccggcggac
    12661 gggctcggcc gaccgcagac cgggccgagg cggggccggc ccggaccggg gcaaggtgcg
    12721 ggtgcgctca gcgtcccgca ccggtcgcgt cagaggagct gcttgccgcc gagaacatcc
    12781 ttggggccgg tgttcttgac gcccgtcacc ttccggaagc cgccggcctt ggtcagtgtg
    12841 ggacgttcgt acgtcatggt cgcactcctt ttcccttggg gaatgacggg aatcacgggg
    12901 cctggccgac gaaatgcaga agcatttgcg ccttcgctcc cgcgagcggt tgtggccgcg
    12961 aggtaaccgt aagagcgacg cgagcatcat cacaacgatt cgctcacggc ggtgtgtagt
    13021 gcgctggggg cgggtgttcc ggttgtcatg tcgcgatgtg atcccatgcg ctccccgagg
    13081 gtgacgcgga ccggtttgaa ggcgcgcatt cctggtccca cgctgctcaa aattcctgcc
    13141 acgagtcaga atcccaggca tcgtcacaac gacggtctcc ccgtcagccg tgtccggtag
    13201 cgtgtgcctc gcatcggcga ccggggcggt gtggccttcg tcgaagggct gtcaggaagt
    13261 gccgccggtg cctcggccga gttcgttcag gaattgccgc tggttgtcca ggaatccggc
    13321 cgcgaagagt gagcggggcg agaagagccc ggtgagcgtg atcctggcgt cggactgctc
    13381 gatggaccgc ttgagtagtg aatgggtcgc gtccgggtag cgctcgactg tcagcgcgct
    13441 gcccccgccc agaatcctat ggtaggtgcg ctccgtgccg gcggtgtcca cgtggacgtc
    13501 gtggcccgcg agggtcagca gtaccggtac gccgcgcagg acacggaggt ctcgtgtggt
    13561 gtccgcggtg tatttcttgg agatgaagcc ccagcgcccg gcggtcatgc cgtccgtgtc
    13621 gccgtgcacg gccgcggcgt gcccgtcgaa ggtcgcgtgg cgtgccagca atcgacggac
    13681 ggcttcgttc cgggcgatcc gggcttgggt gcaggcaggc tatgcgcctt cggcgcgcag
    13741 ctcggcgagg aggtcgtagc ggccctgtcg gagccagttg acggcgggga gacggcgatg
    13801 acgaagctcg ccggtgttcc ggtgccgacc ttcggcagga cccagcccgc ctggctggcg
    13861 ccccagcgcg ggctcgccac tcgctatgac aagacccgtg agtcctacca cgccgccgtc
    13921 accatcgcct cactcctgct ctggatctga ccctttgaag acgatctcta gcaccccggg
    13981 ctgtccgggc cctcaccctc gacgccgccg agcaggccct cggcggtatc ggtccgccgt
    14041 gttcggctgc cgcatcgttg cccggcccgc tcgctggctt cgatcgccgt ggacggcctc
    14101 agaactgccg gctccccccg ccgggctggt gatgcggtcc agtggacgcg tctcgcgtgg
    14161 ggcagaacgg ccgttccgcg ttcccgcgtg gggccgttcg gccccgtgct cgccgtgtcg
    14221 tgggccggga tggtggtggg gcagcgcaag ctggcgccgc cggccggtgg cgccccagaa
    14281 atgatccagg aggcggatca ggacatggtc gtgcgggtgg ggatcaacgg gttcgggcgg
    14341 atcgggcgga actgtctgcg gtgtgtgctg gagcgggtgg cgcggcaggc gacggcggtc
    14401 gaggtggtgg cggtcaacga tgtggcgtcg gccgggacct tgacgcatct gctggagtac
    14461 gactcgacgt acggcaggtt cggcctggag gtcgggacgg aggacggtgc gctggtcgtc
    14521 gccgggcggc gcatagcggt gtgttcggag cccgacccgg ccgctctgga ctgctcggtg
    14581 ttgccggtga ccgacagcgc gggaatcgca gcggggctgg tgtccgcccg gcagatcaac
    14641 cgcgtgccgc tcgaagaccg gcccctcacc acactgcgcg acatcatgcg cccgttggct
    14701 gcaaccgtca cggtctcttt cgacgaaccg gccgacgacc tgttgccccg gctgcagaca
    14761 agtcacgaat gacacgccct ggtcctcgat ccggcgagcg gcaagcttat cggcatcgtc
    14821 gtgccctccg acatccgccg atcggtcacc tggctgacgg cggccaccgg ggacgcggca
    14881 gccgtccagg acggcgaagg ccgcacgaca gcaggaagga agaaggaccg gcgatgaacg
    14941 gaaccgcacc gcgccacggc gagaggggct ctcaccagcg acagggggaa gcaccaggtg
    15001 ccgaccgcat cgaggtaagg cacaacggcg gagagacgta cgcagccggg gtactggatc
    15061 ataaagtgat cgtggaccaa cccgtccctg cgggtgggga cgcacccggt ccgaccccgg
    15121 tggagctgtt cgtgaccgcg cttgccacat gtgtggccta ctacgcgggc tcgttcctca
    15181 agcggcacgg actcgcgcgt gaagggctgc gggtattcgc cgagttcgac atggcaaagg
    15241 gcctccggca cgagtacgga ccgtacaagt tcgcgtcatt ccgcccaaca agctcagctc
    15301 agctcagcac agtgagaggc gctacgggcc atgacgaacc gctgcactgt gggcaactcc
    15361 ctgcgcttgc cgccggaggt cagcgtcgcc gttgacggaa gtggcgtgtc atcggtgcct
    15421 acggcataga aggcggcccg cgacatgacc cgcattgagt tgccgccaac ttgaattcgc
    15481 aggtcaaggg gctggtgtga tcggttccca ggactctcac ccggttcacg ggtgagagtt
    15541 ggatcggtag atcgtccgtc agcgtgttcg acgcccgggc tcctggccat gactcggtct
    15601 cggggtgctg ctcgttcagt cgcggcttgt ggtctgtttc ctggaccagg cggtggcgtc
    15661 ggctccgtac cgcgtcagga gccgtgcgaa ctgggtccgc tcctccggtg accaggcgac
    15721 ggtgatctcc aggaacgctt ctcgctgttc ggcggcgaag cggttgcgtt cggcctcgcc
    15781 gtgatcggtg agttcgagca cggtgcggcg tccgtcggac tgggatgccg cccgccgcag
    15841 cagtccgtcc gctatgcagg cggcgacggt ccggctggcc accggctgcg cgacgcccat
    15901 ctcggcggcg agcccgccga cggtcgtctc gcccggcgcg tcggcgatga cgttgagcac
    15961 gaggttgcgg gagaggtcct tgctcgatgc cggtgcgcgt cgccgcagac gggacagcgc
    16021 cggaccgatc tgatccagcg ccgggtcgtc ggggggctgc tcggaggagg gcgtgctgct
    16081 catacgccga gtctaggccc ggccggcaca tttgcatacc attcaataag tgcatagcat
    16141 tggatatgta aatattgaac gagcttagga aatgaggcgg accgtcatga cgctcaccgc
    16201 gatcaccaac gcgcagatct tcgacgggga gaaggtggtc ggcgtacgga ccgtggtcat
    16261 cgacggcggg aggatcgccc gcatcggtgg cgacgctccc gagggcagtg agatcgtcga
    16321 cggcagcggc gccacactgc tgccgggtct catcgacgcc catgtgcact ccgccccggg
    16381 ttccctggcg ctcgccctgc ggttcggggt gacgaccgaa ctggagatgc aggggatgaa
    16441 cacccgggag aaccgggggg ccatcaccga cgacgacaca caggccgatg tgcgctcctc
    16501 cggcttcgcc atcacaccgc ccggcggaca cccgagcgag ctgatgcccg aagggttccg
    16561 gcccaagtgg gaccttcccc cggtgatgcc cctgatgccg ttctccacca cgcccgagga
    16621 ggccgccgcc ttcgtgccgc agctcctcgc ccggggctcc gacttcatca agttcatgat
    16681 cgacgacggc agcgtggagg gacaccccgg gctgcccgcg ctcgaccagg ccaccgtgaa
    16741 tgccggcgtg gccgaagcca agaagtacgg tgccctgacc gtggcccacg cgctgaccgt
    16801 ggaggccacc aggacggccg ccgaagccgg cgtcgacggc gtcacccacg tgttcatgga
    16861 ccagccgcac accgccgaga tcatcagcct gatcaaggac gcgggcatgt tcgtcatccc
    16921 ctgcgtcact ctcaacgcct cgatgatggg ggtcaccggc agcgaactcg ccgacgaccc
    16981 ccgggtcgcc gcacgcctcg acgccggctg ggaccggacc ctgcgctcca gctacaaccg
    17041 ctacccgcag ggcaaactcc acgacgtgta cgacaccgtg cgcgcgctgg acgccgccgg
    17101 cgtcgacgtg ctggccggca ccgacgtctc catgcccgag acgttcttcg ggggcctggc
    17161 acacggggcg agtctgcacc acgaactgca gtacttggtg caggccggtc tcactcctgc
    17221 acgggccctg cgcgcggcca cggcgaccac ggcccgccgc ttccgcctca gcgaccgggg
    17281 tcgcatcgcc gagggattgc gcgccgacct tctgctggtc gacggcgacc cggtcagcaa
    17341 catcagcgac actctcaaca cccgtgccat ctggcgccgc ggcacccgcc tggcggcatg
    17401 accgcagcac ttccccttga gggaaggact caactgtccg gttcttgctc gccgcggtac
    17461 ggcgaccttc tacgatccgc tgcatgctcg gatcccgagc tgctggaacg gatgaaacag
    17521 tgaggacagt ggggagccgt cgtccaggtc atgctgtcgt tcgatcaggc cctcgcggag
    17581 ggtgtcctca agcgacagcg tgtccgaggc atcctggggc ggagtgagcg ccgtcccgat
    17641 gtcttccacc ggcacgtatc ccgggtcatc gtccaggggg ccgcgtgcag gaccagggcg
    17701 atggccggca gagcgttcgt gaaggggccg ctgctgtagg tcttgggcca gaccggctcc
    17761 aacgatgtag ctgagcgggg caatgactcg gcccaccgtt gatttcgcca gtcgtcgtcc
    17821 ttcgcaaggc tgaaggccat ccggcccgct gcccaccaca gatcccgcat gtcggccatg
    17881 ctgcctacct acggcccacg gggtgtcctg tccgcccctt gccggccgtt cccgatcagc
    17941 cggcggagtc ggccgccgcg aggtcgaggg cgatgtccgt gatcatgtcc tcctgaccgc
    18001 cgaccatctt gcgccggccg acctcgacga ggatcgcgcg ggtgtcgagg ccgtgccgcc
    18061 gggcggcggc ctcggcgtgg cgcaggaagc tggagtacac gcccgcgtag ccgagggtga
    18121 gggtctcgcg gtcgacgcgg acctcgcggt cctgcagggg acgtacgacg tcgtctgcgg
    18181 cgtccatcag ggggaacagg tcgcagccgt gttcccagcc catcaggtcg gcgaccgcga
    18241 cgaacgcctc cagcgggcag ttcccggctc cggcgccctg gccggcgagg gaggcgtcga
    18301 cgcgggtgac gccgttctcg acggcgacga cggagttggc gacgcccagg ccgaggttgt
    18361 ggtgggcgtg aatgccgatc ccggtgtccg gttcgaggac gtcgcggtag gcgcggacgc
    18421 gatcgcggac gccgtccatg gtcaggcggc cgcctgagtc ggtgacgtag acgcacccgg
    18481 ctccgtagga ttccatcagc ttggcctggc gggccagttc gccgggttcg gccatgtggg
    18541 acatcatcag gaacccggcc acgtccatgc ccaggtcgcg ggcggcgccg atgtgctggg
    18601 cggagatgtc ggcctcggtg cagtgggtgg cgacgcggac cgagcggatg ccgagggcgt
    18661 gggcctgccg caggtcgtgc agggtgccga tgccgggcag gagcagcgtg gtgggcaacg
    18721 cgtggtgaac gctgtcgcag acggcttcga tccactccca gtcggtgtgc gcgccgacgc
    18781 cgtaggtgat gctggagccg gacaggccgt cgccgtgggc gatctcgatc gcgccgaccc
    18841 cggcggcgtc cagcgcggcg gcgatggtgc gggcctggtc gacggtgtag aggtggcgta
    18901 cggcgtgcat gccgtcccgc agggtcacgt cctgtatgta cagggcgggg ggctggttcg
    18961 gagtcatcgg gagaccacct cggtgaaggg ctgcgcggcg gacatgcgct cggcggtgcg
    19021 cagggcggcc gaggtcatga tgtcgaggtt cccggcgtag gcgggcaggt agtgggcggc
    19081 gccctcgacc tccaggaaga ccgagacctt cgcggcgccg gtggtcttcg tgccgacggg
    19141 cagcagtgtg cggagggggt cgtcgtcggc gacgcgttcg aactggacct tctgcttgag
    19201 gcggtatccg ggcacgtatg cctggacccg ggcgaccatc tcctccaccg atgcggtcac
    19261 cgcggcgtcg tcgcactcgc tgaccaggca gtacacggtg tcgcgcatga tcagcggagg
    19321 ttcggccgga ttcaggacga tgatggcctt gccccggacg gcgcctccca ccttctcgat
    19381 ggccgacgag gtcgtctcgg tgaactcgtc gatgttggcc cgggtgccgg ggccggccga
    19441 acgggaggag atcgaggcga cgatctctcc gtagtggacg ggcgtcacgg ccccgacggc
    19501 ggccacgatc ggaatggtgg cctggccgcc gcaggtgacc atgttgacgt tcggtgcgtc
    19561 gaggtgggca tcgccgttga ccggcgggac gacatacggg ccgagcgcgg cgggcgtcag
    19621 gtccacgacc ctgcgcccca gcgagcgcag cacctcgtcg tggtggcggt gcgcgccggc
    19681 cgaagtggcg tcgaagacga tctcgacgtc cgcgaactcg tccagcctca ccaggccgtc
    19741 gacgccctcg tgggtggtgg cgaccttcag gcggcgggca cgggccaggc cgtcggagtc
    19801 gggatcgatc ccgaccatgg cggcgatctc cagggagtcg gagagccgca ggattttgat
    19861 catcaggtcg gtgccgatgt tgcccgaccc gatgacggcg accttcgtgc tcatgctgcg
    19921 gtcctttccg tggcggcgga tgcgaacgtg gtcgtgaccg tgccgagccc ttcgatgtgc
    19981 gcggtgaact cgtcgccctc ggcggcggcg gccatcgggc cgagcgcgcc ggtcaggacg
    20041 atgtcgccgg cccgcagcgg gtcgccgagc ccggcgaggg tggaggcgag ccagagggcg
    20101 gcggtgaggg ggctgcccag gcagtcggct ccggtgccct cggagaccgt ctcgccgttc
    20161 ttggtgagga tcatcgtcac ggcccgcagg tcgacgcggt ccaggggggc gggggtgccg
    20221 cccaggacgt acaggccgca ggaggcgttg tcggcgatgg tgtcgacgat ggtgatgtcc
    20281 cagtcggcga tgcggctgtc gacgatctcc agggcgggca gcgcgaaggc cgtggcgcgc
    20341 agcaggtcgg cgacggtcgg gtcgtgatgc ggaaggtccg cgccgaggac cagggcgacc
    20401 tcggcctcga ccttcggctg gaggagccgg ccgggggcga tcgggcgtcc ctcgggcacc
    20461 gccatgtcgg cgaacagcgc gccgaagtcg ggccggtcca cgccgagctg ccgctgcacg
    20521 gcgggcgagg tcaggccgat cttgcggccc accagccgcc gcccggcggc gatcccgcgt
    20581 tccacgtgca ggcgctgcac ggcgtacgcg gcttcgacgt cgccttcggg caggcgcgag
    20641 cgcaccgggg cgcagggggc gccggtgcgg gcggcctctt ccagggcggc cgccgccttg
    20701 tgcacggcgt cggcgggctc gtgggcgctc acgatcgccc ccggcgggaa gtggtgtgga
    20761 gcgaacatgc gggagttacc tccggtcggg gaggggcggg gttgtgggag gggcggcgac
    20821 gggagtccgc cgctgcatga caggtatagg cgtacggtcc gaacagcggc aaaatatgga
    20881 tcagtcgtcg gcgatgcccg cgccgctgag agcgggcacc gtgttctcgg ggtgagcgag
    20941 ggagcgggcg ccggcacgga actgggcgag cttgtccacg atggtctggc cgacggggag
    21001 gtggccccag acgctgatgc cctggtgggt ggagggttcc cagatcgtct cgtcgatgac
    21061 gatcgggttc cagccgactt cccattcgaa gcccgagggg gtgcgggcgt agtaggagag
    21121 ttccttgtcg ttggtgtgcc ggccgaccga cagcgccata tcgaagccga gttcgtgcac
    21181 ccgctggtag ctctgggcca cgtcgtccag ggtggcggcc tggatgttga ggtgctggac
    21241 gcgggtgcgg atcgggtcga tgggcagccc gcgggtggcg gccaccgcga tggagtggtg
    21301 gcgttcgttg acgcgcagga agcggatctt gagtttgacg ccgctgatgg tctcgtcgat
    21361 gtagtcggtc aggcgggcgt cgaagacggt gttgaagtag ccgcggatct gcgtcggcct
    21421 ggtggaggtc agcgcgacgt gtcccatgcc ggagtcgccg gtaacgaagc ctgacgcgag
    21481 catgcgcagc ggttcggccg acgtcagcgg ggtggtgtag atctcctggg tgatgccctt
    21541 ggggccgggg aaccgcagga ggcgctccac gccgcgcagg gcggcttcct cgtccggccc
    21601 gcgtacgaca gggacgccgt gggcccggat acgggcctcg atctgctcga aggaggcgtg
    21661 gtcgtcgatg tgccagccgg tagcgacgac gtcctcggcc gggccgcgcc tgagcaggaa
    21721 gcggcattcc tggtcgtcga ggcggaagcg catcaggtcg cgggagaggc tgtcgtggtg
    21781 catgccgatg gcgtcggtac cgaagcggcg ccagtcggcg aagcggttgg tctcgatgac
    21841 gatgtagccg agatggacgg cgccgaagac ggaggcggtg ctggtcgctg cggtgttcat
    21901 cggcggcccg ccaggaagtc tgcgcacagc cggttgaaga gctccgcgcg ttcgaactgg
    21961 acccagtgcc cggtgttggc gacgagatac aggtcgcagt tgggcatgcg ctcggcgagc
    22021 atccggccgc cggacggccg gttgacccgg tcccgcgccc cccacagcac cagcgtgggc
    22081 acgggcagcc gggacaggcg cgcatcgcgg gtgaagtcca tcttccatac ggtccgcagg
    22141 gcgtcgggcc cggacggccg tcgcagcggc ggtgaggcga tcacttccgg atcgatgctg
    22201 gcccggtagc gctcgtcgat cgcagcgtcc gggacgtcgg cggcgttgaa gacgagatag
    22261 ttgcggatga acttctccag cttctgccgc gaaggcccgt cgccgctgta gtagttcagc
    22321 aggctgttga gacctggggt gggcagggcg cgggtggtgc cgatgccgcc ggggcccatc
    22381 aggaccatgc ggtcgacccg gtccggggtg tccagggcca ggcgcagggc gcaggcgccg
    22441 ccgtaggagt tgcccaccag gtgcgccttt tccaggccca gttcgtcgag cagtccgcgt
    22501 atgccgtcgg ccagatggcc gaaggggtcg ctgccgtcga cgcccttggt gctacggccg
    22561 tagccgggca gatcgggcac gatgacccgg tactccttg
//
