LOCUS       NZ_LWKZ01000023        23574 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02923 scaffold3, whole genome shotgun sequence.
ACCESSION   NZ_LWKZ01000023
VERSION     NZ_LWKZ01000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02923
  ORGANISM  Streptomyces sp. CB02923
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1243511)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1243511)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905005.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:56:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,128
            CDSs (total)                      :: 8,049
            Genes (coding)                    :: 7,904
            CDSs (with protein)               :: 7,904
            Genes (RNA)                       :: 79
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 32 of 145
            Pseudo Genes (incomplete)         :: 128 of 145
            Pseudo Genes (internal stop)      :: 11 of 145
            Pseudo Genes (multiple problems)  :: 22 of 145
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 505978
            Orig. end                         :: 529552
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWKZ01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23574
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="2dos"
                     /region_number="7"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /tool="antismash"
     cand_cluster    1..23574
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23574
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13574](+)"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13574
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     misc_feature    123..138
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(156..171)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.64"
                     /tool="antismash"
     gene            complement(728..3145)
                     /locus_tag="A6A06_RS20770"
                     /old_locus_tag="A6A06_14005"
     CDS             complement(728..3145)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS20770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_14005"
                     /product="hypothetical protein"
                     /protein_id="WP_199931025.1"
                     /transl_table=11
                     /translation="MITRDMLSGLDACEPEAQDALLAYLAAVIAHRTAPVHTAVAFNAV
                     YFGYDVEAGGYVGGPLDFEDFPSVALGDRLEALPVGAMINIRTGGDLLPAEIVYKEGAH
                     AGLGPYGETPDWLSGAPAGARGPGLLAPDEVPVLRERLVFDTSAFGQDLAPTRARLQRL
                     RRRGRTDDFGHLVVEARYEWADPDLSDADHYARYLVTSGRDQLTSALVPTPLPTLLAPG
                     GGGAELLTAVKGLMRTLRQALAELSGVRVWGDYAFTRASLAQRLAVPGPLGRDDLARLA
                     DSTVRQAIPRAGRRIMAIPPRPVYTALGAALRSHPQWQDQLHGTDYPLAVCHANSVVSD
                     YARREQEEATGLLPSGVRLSLDDRWQGGGVWRAEFVPSGSDPAPGTTEKPVGRGWADSL
                     PHRPDHRTSSAPIPTPPPCPEPPSGLQDHPGTVLPPPPGADASPASPDEALSAAEPTSA
                     DAEETALPLLWPDDSRLGFPIELAASDSQIEWAQPLRLFHVLQECLPLPEHVVAELLPS
                     GAPQRAVRIVLHHEGRNLPAAQSCHDTCVTVDRQGTRLDGVEWPLDLFPGIWLTFTWQR
                     GSGVIHARTTMLPQPVTVDGELMEHRYDPRVLTRDGTQRLCTGAEPADEVVPSHRAVTT
                     VQLLTAVRRLGLLDRFGCALLARTDLPAAVRAVTGEDGLETTGIESALSKLLGSELLSV
                     AWGSRGADSSTHHPPRPGEPAVELVRYRPHRVDVEGASFSEGSGLVPPASADRAVREHD
                     VAGFLRRIGHLKKEATSEQRALYREDHRRFRLSGPDELPDGFTYVRPHKRSR"
     misc_feature    complement(2462..2464)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3150..3170)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.08"
                     /tool="antismash"
     misc_feature    3167..3187
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            complement(3199..9276)
                     /locus_tag="A6A06_RS20775"
                     /old_locus_tag="A6A06_14010"
     CDS             complement(3199..9276)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012492.4"
                     /locus_tag="A6A06_RS20775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14010"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_073762775.1"
                     /transl_table=11
                     /translation="MGTSSSKRASAAAAPLIQLVAAHPRGITVEDLIAAARDRFKRVPP
                     QRLAGLLDQALSAGQLHERDGLLFTGEGAGLQEAAARSGEPDARRGIRAVAIDTESVVR
                     TTATPPYVDRRIFQIGAVRTGTDAAWIEEQPSLQVFLSLPDDDWAIHDEGLREQQQARA
                     LVPRAALERVREFCTTTDVLVAHNGIAADFPLLDEACEREDLPPVPGDRVDSLYLAHCL
                     WPLARSHRLALLCDAQEVDRSGLRWHNAADDAELLVRFLSRCAGELASRPMNLCALVTA
                     ACPDSPAWRLLNDLARAAPGPAAAIDPLVIWDRPTVSAALAGWLRDHTPRRSGPPAAAP
                     GRRALAVPGQLRSDGRVDPGALAKVVHGAAARSRPAQQQMTAGLHSWADAGIPALVEAP
                     TGTGKSFAVLAAAMDWLGGGETRSVVIATYTKHLQSQMARDVDILSRAMPGLLSATDLV
                     KGRGNRLSLRALAAALSDATALGTATVSRTRSRFVEHTRFRELGIFLLLRLVAASSAPA
                     MWTARSVDSVDVPAFLDAYCGPTLALWLQSLSQTDGDYAATAATPLAVHTNSVREAIAS
                     HRLILANHAVLLAHLEDLRSLPGETMLIVDEAHLLEDAATSALTVSLDYGAVEQLAASA
                     RTWLKDATSGPARERVAHAVVELETLLDHESLPHAASRAFDALGGQDASVVGARSVTLA
                     SPYGGSSGLGQVRALIALIRRLSSTALRLERALAAFAQAHASALDFFSMDALSVMQTQV
                     ADLRETAESLLSDAQEVLGALPSEGHTSGRAHPDVEPVAPVEGEEEQGEEPESETDADD
                     AADDVLLTDGVLDAQAGLLPPPLPNRIVYAEELAIPLTGLRHYRFRISSSPVELPADAR
                     WRRFLNLFPRTYYVSATLRVAGSWDYIMGRLGLAGLAAMCVDTPFDLRRQAELICFSDF
                     PSWAEQQEGAMRTVAHQLGGYATELVRPGTRGRSADGGALVLTTARSTAAGIAEFLTEE
                     LHRRGDPTHVVNALALGNSRAFEQFTDPGSGGGFLVGTKGLWQGVDVSDEHRLRLVWIN
                     KLPFAPFAAPLVEARRTAVRARAEAAGREDPDAHATEHYYIPLAALQLRQAVGRLIRSE
                     RHRGVVVISDRKLAGHTALRRAYRRAFLGSLDQGLLRTDPHTGEPGAANVATMTEGWAR
                     IWSFFVRHGLLSPQRGKELSEPGALQRHTLLPQTLRIRQLELSVEDVSKLAADDQLQEE
                     VLRRASEVAGLLRLMDDPSDFRLKPAQRTVIEGVAQGRNVLGLLPTGYGKSFTFQLPAL
                     VLPGVTLVVSPLVALMQDQALELNRSIGGAVRALIAPLRESSSRAGKTEVADQLLGRAN
                     HGIKIVYVSPERLCQRRFRELIRAAAEAGVLSRVVLDEAHTMVQWDDFRPSMQRVEQFL
                     RQLRRCHAVPVTALTATANHVVHAGLRAGVFEVPEDSPPPDSEAARREATRPVDDGGLV
                     TVRENPIRPELAVFRRSLNQSSPAVVAGLARHVLEALTGHAVFYCLTVKEVTALHAYLQ
                     EYVGDLGVRVRRFHGRLSQAEKSAVMTEFREAPRSGEEGFAPLVVVATSAFGLGIDRDD
                     VRTVFCVSAPTDLASLYQQLGRAGRDVAGSGSSVEPGAPANTALALLTSRGLRTVAFMT
                     GQDLHPELVRRMGRAVLACKGVLDARDVADRLIGEDARSGRISIQEARSARVTDTYVAG
                     VVRAFSHLARLGRVSDHGDFPPLCKVRRGELCPEDDEESVVLEILEVVNALPESQSPAL
                     RLARARLDVVALDGLLTVRVAGYRELVEGPAGTWQLLSDLHDRGLLDVSAAPSRHWVSG
                     IAVHRSELPVDFLTAMSGKARRAAAEIARLRDFFDDSAACAHRKFADYFGVTELPEGCC
                     TTESNRCGACWGRPDWPAGETMPVSAKALLTPKPRPIDSSALPESRLRRLDEQVYRLIW
                     AVPRGVHARSVWRALRGEDSSYSPKVGRRVRLPQGLTGSRYFGAHADVPLRGVEESIER
                     LAQARRVTSSGKWWRVMPSGSTGDPAVREGETG"
     misc_feature    complement(6151..6153)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6823..6825)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9094..9096)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9369..9386
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.54"
                     /tool="antismash"
     misc_feature    complement(9380..9396)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    complement(9662..9675)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    9782..9798
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     gene            10001..11008
                     /locus_tag="A6A06_RS20780"
                     /old_locus_tag="A6A06_14020"
     CDS             10001..11008
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012335.4"
                     /locus_tag="A6A06_RS20780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14020"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_274535882.1"
                     /sec_met_domain="ADSI-DH (E-value: 2.3e-155, bitscore:
                     512.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 5.3e-26, bitscore: 86.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.4e-15, bitscore:
                     53.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEAPERAVLTERAMPEPAPGEALVRLAYNSVCGSDLSFYKGVWH
                     GSTYPVVPGHEWSGTVVDVNGADSGLVGADVVGDLTCSCGACRHCAEGKPTLCGDLQEL
                     GFTRDGACAEYMTIPAANLHRLPAGTSLRAACQVEPLAVALNAVDRLAVAPGEKVAITG
                     AGGIGLLLALAVRQRGGEVTAFAEPVAERREAAASLGVAATVGGAPGDLVALVEKHPEL
                     RPDVVLEASGYPSAVQEAIEAVRSGGRVGLIGYRVEETGPMAPQHIVIKMLTLQASMGP
                     GTRFGEAIELLSSGAVDVEALLSHEFALEDHARALDVALRRADGNTRSFFNLRT"
     gene            11089..12363
                     /locus_tag="A6A06_RS20785"
                     /old_locus_tag="A6A06_14025"
     CDS             11089..12363
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (27-180). E-value:
                     1.3e-07. Score: 22.9. Matches aSDomain:
                     nrpspksdomains_A6A06_RS20785_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970228.1"
                     /locus_tag="A6A06_RS20785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14025"
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_073762777.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.9e-107,
                     bitscore: 354.5, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-06, bitscore:
                     23.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQSLAVQGGSAVRTRPWPLWPRPAAGAAEAVQQVLSSGRWSISG
                     PYRGTDSHERRFARAFAAYNGVPHCVPAASGTASLMLALEACGVGAGDEVIVPGLSWVA
                     SGSTVLGVNAVPVFCDVDPRTLCLDPAAVEAAVTERTKAIVVVHLYSAVADMDALTALA
                     ERHSLPLIEDCAQAHGAAYRGVKVGALATAGTFSMQHSKMLTSGEGGAVVTRDADFARR
                     VEHLRADGRCLAGQRPAPGEMELVETGELMGNNRCLSEFQAALLTEQLKELDGQHAVRR
                     RNAALLDDLLGESGYVPQETSEGTSTRTHYTYAARLPEGHLTHVGVAAVAGAVSAELGL
                     TVAPSYAPITRNRLYDPGSRRRYALGVEHQALTDPKRFELPVAEAAARRVLTVHHAALL
                     GDENDMRDIAAAFGKVLRHGADLTE"
     aSDomain        11170..11628
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A6A06_RS20785_Aminotran_1_2.1"
                     /evalue="1.30E-07"
                     /label="A6A06_RS20785_Aminotran_1_2.1"
                     /locus_tag="A6A06_RS20785"
                     /protein_end="180"
                     /protein_start="27"
                     /score="22.9"
                     /tool="antismash"
                     /translation="AAEAVQQVLSSGRWSISGPYRGTDSHERRFARAFAAYNGVPHCVP
                     AASGTASLMLALEACGVGAGDEVIVPGLSWVASGSTVLGVNAVPVFCDVDPRTLCLDPA
                     AVEAAVTERTKAIVVVHLYSAVADMDALTALAERHSLPLIEDCAQAHGA"
     misc_feature    complement(12415..12429)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            12420..13574
                     /locus_tag="A6A06_RS20790"
                     /old_locus_tag="A6A06_14030"
     CDS             12420..13574
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013887.4"
                     /locus_tag="A6A06_RS20790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14030"
                     /product="2-deoxy-scyllo-inosose synthase"
                     /protein_id="WP_242440893.1"
                     /sec_met_domain="DOIS (E-value: 3.5e-173, bitscore: 571.3,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.1e-69, bitscore:
                     230.4, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVTAITMEDATFPYRLGTDCAEEIVARLGDRAASRYLVVCDTTV
                     AALYGHDLVARLEKDAGPAVLLTHEAGEVHKDVTTVGALAEQALGAGADRRSIVVALGG
                     GITGNIAGLLAALLFRGIALVHVPTTVVAMLDSVLSLKQAVNASFGKNLVGTFYQPAEV
                     LADTAMLRTLPVRELRSGMGEVVKNALAIRPSMTERLAGLLRPDGRYDDDALRWIIAES
                     VAAKADVTGADKHERRDGLVLEYGHTAGHAIEHAARGEVAHGAGVAIGMVIAAEVSHRL
                     GHASAPFVALHRELIAKAGLEHAVPAFVGTDDVKNWLTYDNKRGYLDCEGTSTPMVLLS
                     GPGQPLRTGGMPLVPVPLSVLNETVDALAGPGRTGADHRAAVPV"
     gene            13649..14899
                     /locus_tag="A6A06_RS20795"
                     /old_locus_tag="A6A06_14035"
     CDS             13649..14899
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF045194.1"
                     /locus_tag="A6A06_RS20795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14035"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_073762779.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.6e-30,
                     bitscore: 101.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLRLTPFFHHDQVENWPAEYDAVGGMQVQILGLSRELADRGVD
                     QQVMTVGFPGLPRWRRDRPGLVVRITRAPLPRLRSELTGLVGLNQAWLLGALAACARLG
                     RRWRPDLIHVHADGQLWALLAGPLAARIVGAPYCLTLHCSRLAVYEPMSRLDRWQHRLV
                     RAVERHTLRHAAGVSTLTARTADVVARALPMDRSLIDVVPDSVGEVGPRPEAAAALRRD
                     LDVPEGAPVIGYVGRVAHEKGWRDFVAMAARWRAGPGAGAAVFLVVGDGPQGDRMRKAV
                     ADAGLTDRFRFTGFLPHAEIPAVMTALSVLVMPSAHEELGGSAIEAMMCGTPVAGYAVG
                     GLRETVGGVTPGLLVPRGDVAALTRAARDAVQEPEHVRQSVAGARQRLASEYGSGAATD
                     RALAHYRRVLRTKGAAR"
     gene            14896..16701
                     /locus_tag="A6A06_RS20800"
                     /old_locus_tag="A6A06_14040"
     CDS             14896..16701
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="A6A06_RS20800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14040"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073762780.1"
                     /transl_table=11
                     /translation="MRYARTGSLWRCLRYLRPYGWFMAGAFGTALGAMLAGLAMPLVLQ
                     RLIDGPLAHQDMGALPGLIAGFAVLGAVEAVLLGARRLLVVRPATHLETTMRARLFQHV
                     QRLPSSFHSHWSSGQLLSRTVSDVTEIGRFFAFSAVYLLVNVAALVAGLGVLAWLSPVL
                     ALVVLVTYLPMVAATVFFEQRFHTVARSAQEQSGDLTTTVEESVAGIRVLKAFGRCPET
                     VRRFTAQARALRGTELRKISLTAALWWTATALPELGIVALMGYGGYSAATGQLTLGVLM
                     AAITVATYMRWPADTLGWLVADASTAGAAATRYWQVRDIPLAVSDPATPRPLPHPLRGE
                     LRLENVHYRHPEGKDAILRGIDLTVPPGTTLALVGATGSGKSTLVSLLTRLDDPTAGRV
                     TLDGTDLRDLTLDALRSAVTCAFDDPVLFSGTVRHNVALGLPDGTRDDGRIHAALRLAH
                     ADGFVAALPEGLDTRLGEEGTGLSGGQRQRLALARAVLPGPAVLVLDNALSALDVHTER
                     EVEAALRTVLGQVTTVLVAHRPATLRLADRVALIADGRVAATGTHDELMATHAAYRDLL
                     ESPVTGPAGADGAPLRGTARKVQAR"
     gene            16698..18563
                     /locus_tag="A6A06_RS20805"
                     /old_locus_tag="A6A06_14045"
     CDS             16698..18563
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958279.1"
                     /locus_tag="A6A06_RS20805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14045"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073762781.1"
                     /transl_table=11
                     /translation="MTDDTATATSRPRTEDLPGGPADTDSDRLLRDRRNRLLRTFLRPE
                     RRRLALAVGLALLENLSSLVTPLLIAAAIDRGLPAATDGDWGPLTTYASLALGAGLATA
                     TLKYGFLRYSGAIAQSLLFHLRHRTFAHALRLPLSFHEASPSGSVVARLSSDVESVEEV
                     LEMGLDGLFSALFSMVGIIAVMIWLDLPMAAVVLALFLPLYLLTRWFRRRSRAAYRRTR
                     GATEHVVRHTGEAYNGIKAVQAFRKEDANAAELRRLDSGYAAARAASGRVSAFFSGGVK
                     LIGNLSLTLLMAFGAVRIAHGQLEAGTLAAFLLYVHRLYDPIDELASFANAFSAASAGL
                     ERIGLLFHATDTLPGPDRPVPLPPAAAPGRVRFEDVRFRYAPGSPYVLDGVSLDLVPGQ
                     TVALVGTTGAGKSTLAKLLARLYDPAAGRITVDGVDLRDVADPELRTHIAMITQEPFLF
                     SGTVAHNIALGRPDATPQEIRQAARAVGAHSFITGLPDGYDTDVRKRGAGLSAGQRQLV
                     ALARTMLAAPRVLILDEATSSMDAPSERAVHTALDRVLTGRTALIIAHSLTTVAIADRV
                     LVLEDGAVVEDGPPAVLATGDGPFARLHHSWLSATDRRAHHSSDH"
     gene            18577..20217
                     /locus_tag="A6A06_RS20810"
                     /old_locus_tag="A6A06_14050"
     CDS             18577..20217
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.4"
                     /locus_tag="A6A06_RS20810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14050"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_079194171.1"
                     /transl_table=11
                     /translation="MERLRGPSPLENTAARHPAPLGPAHRDGLGPGTADRVWDVCVIGS
                     GASGAVAADRLVRQGLDVLMIEEGFRLAPHVGLDEAESLSRQALARDDEGNWTDEGWPW
                     TTSNLGGGTVYYGGASFRYRPFDFDPGELVHTDGVDVRWPYTLADLAPYYEVLERRLGV
                     CGGDAPGAARGSRHSRGPAHQPSPAARVLRAAGESLGYRPFPTPLAINRDAHDGRAACN
                     RDSLCVSHLCPTGAKGDVVSVFLAPLAAHPNFALRTGVRALRLEQDRSGEAAAVSCLDR
                     QTGQAHRVRARVFVVACNAIQSAALLLRSRTPYSPDGVGNHSRMVGRGLCMKLSEYVSG
                     TVDAEPAVLADPRTNTGPFSTVAFLDHYLDADCPGGFGGLIYESKRDQRHKLVHDALEL
                     RVETILADHPSLDNRVGLSGRLDEDGMPAVVIDYTPDPRDLDRLRYMTGRCERLLHTAG
                     ARGIRRKRTGFAQGSSHLHGTCRAGHDPARSVVDAWGRVHSADNVYIVDGSFMPYPGGL
                     NPTLTIQAHALRTSRAIASHLAADRAAHV"
     gene            20245..21144
                     /locus_tag="A6A06_RS20815"
                     /old_locus_tag="A6A06_14055"
     CDS             20245..21144
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS20815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_14055"
                     /product="radical SAM protein"
                     /protein_id="WP_073762782.1"
                     /transl_table=11
                     /translation="MDTPVVWPPRTRRIRTYRNIVIDGACNLRCTYCEVKAIKVDQVAT
                     NASLDKIFERYEPGNTLFRVESNGEIALYPKILDHLQGRAADGWHIEVLSNGTRLPRCL
                     KGRENLMWVFSVDGHTARMNAKRGMSQEQVDRILDTAVELGAELQMVYHDQSLEEVNEF
                     IDLLSARNYTGLLHFMPLLAFKGRPLTVNLRYEDLHPAPFLAPSEYFRRWNHIFETGKR
                     DAVCDQISNGYNYSVSDDRIEMVKCDCYSVPKHLYHDFGDIREFDNWPCGTCIANQEFN
                     NSRPRMQVPEGRITLPLV"
     gene            21141..21830
                     /locus_tag="A6A06_RS20820"
                     /old_locus_tag="A6A06_14060"
     CDS             21141..21830
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012521.4"
                     /locus_tag="A6A06_RS20820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_14060"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_073762783.1"
                     /transl_table=11
                     /translation="MSTAQRFVLVRHAQAAVNILGDDDLMTAHDTDADLTPLGEEQARA
                     LAGHLAGDRAAWPGPPGADAYRLYTSPQRRARRTAEPLARLLGLAAVTDPLLAEAHSPP
                     RFPRPLRVREWDAVLEERLRRTDAEIAGVESWTAQRARVRRFLRERCGDRPGAGFVLVS
                     HAETIQALLLELLGLDDSVLLAARFKVSNTGVFIVDRTVDAPTDGTEQPCGYLVVANSK
                     THLARTA"
     gene            21827..22909
                     /locus_tag="A6A06_RS20825"
                     /old_locus_tag="A6A06_14065"
     CDS             21827..22909
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS20825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_14065"
                     /product="hypothetical protein"
                     /protein_id="WP_073762784.1"
                     /transl_table=11
                     /translation="MSGAPEPGRATGSSPDAPRALFEIYDEGFACDTWGGVETALWSLA
                     EGLRALGVQADFYPSSQGTDLEALAGRVARERTDAVFPLVESALFRGDRWRRLPALHRR
                     VVRIWHDVSHLTPDLTTPPPCPAHTPGTAPDPDAGCPATPAHPDGPMREVFLRDLPWTR
                     CFPDRAYIPWAADHLPAEDLRDIRGPVVIQLGKTPVEDAERCLTRLLEARLPVRAVFAT
                     WSRQGRAARDLVHERAASGDIEVFDTYDIRTDWKRVYGGARLFVLPSVFHETFNFAAAE
                     AVQLGLPVATLADCGALPGFASLTAATVEDLMDRVVTDGASVRPRPRSRTGWDEVARHY
                     ARLITTTGDRARHEEAACRT"
     misc_feature    23459..23479
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.96"
                     /tool="antismash"
ORIGIN
        1 gtcttcttcg ggcgcgacgg gcgtccgctg cgcgagttcg actacccggt gtgcggcttc
       61 ccgtaccgcc tggaccggga cgtcggtctc cgccagccac ggttgctcca gcgcccacgc
      121 ccaaagggaa gcatcctcgg agctggccct gaggtgtgac cagaccgtca actgcagcag
      181 ggcgggagtc catcgatggg tgagtggacc aaggccgtcg tccgacgggc ccacggtgtt
      241 ctgctggccg gcccgggcca ggtcgtcgac gacgggcagg ctcagatgca gggccgcctg
      301 acgggcgcgg ggcgcttcgg ggtcgcgttg aatacgggtc aggacgtcgt ggcacagggc
      361 acggttgacc ttggttccgt ccatggggat gcggagcgtg tgcagcagat ggcgccgcca
      421 cgatacgcgt gtcgagttga gcgcgtattc gacgtctgcc tcgctgaggc gcaggagcgc
      481 atcagctgtc ggggacgggc gcgcgtccat ggaccgggtg agtgcggcag ataactcctc
      541 cagagccgcg agcaattcgg gcggcgtctc attccgctcg cggttgccaa ggtcgacagg
      601 gtaaggggtg tccatctctc cacctgacac ggcgcgggac gggcgagggt ggctcatacg
      661 ggctccaacg gctggtgcgg gtcgtgcgga tggtacgggt gatgcaggta cgtcgtggat
      721 atcggaatta tcgactccgc ttgtgtgggc gtacgtaggt gaatccgtcc ggcagttcgt
      781 cgggaccgct cagccggaac ctccggtggt cctcgcggta cagggcgcgc tgctctgaag
      841 tggcttcctt tttgagatgc ccgatgcggc ggaggaaccc ggccacgtcg tgctcgcgca
      901 ccgcccggtc cgccgaagcc ggcgggacga ggcccgagcc ctcggagaac gaagcgcctt
      961 cgacatcgac gcgatgcggc cgatagcgga cgagctccac ggccggctcg cccggccgtg
     1021 gcggatggtg tgtgctgctg tccgcaccac ggctgcccca ggcgaccgag agcagctcgg
     1081 agccgagcaa cttggagagg gctgactcga tgccggtggt ttcgaggccg tcctcgcccg
     1141 tgacggcgcg gacagccgcg ggcaggtccg tcctggcaag caacgcacag ccgaatcggt
     1201 ccagcagccc gagtctgcgg accgcggtaa ggagctggac ggtggtcacg gcccggtgcg
     1261 acggaaccac ctcgtcggcc ggttccgccc cggtgcacag cctctgtgtc ccatcacggg
     1321 tgagcacccg cggatcgtaa cggtgttcca tcagctcgcc gtcgacggtc accggctgcg
     1381 gaagcatggt ggtccgtgca tggatcaccc cgctcccgcg ctgccaggtg aaggtcaacc
     1441 agatgccggg gaacaggtcc agcggccact cgacgccgtc gagacgtgtt ccctgccggt
     1501 ccaccgtgac gcacgtgtca tggcacgact gggctgccgg caggttccgg ccttcgtggt
     1561 ggaggacgat ccgcacggcc ctctgcggag caccggacgg gagaagctcg gcgacgacat
     1621 gctcggggag cggcagacat tcctgtagga cgtggaacag ccgaaggggc tgagcccact
     1681 cgatctgact gtcgctcgcc gccagctcga tgggaaaacc gagacgactg tcgtcaggcc
     1741 acagaagcgg aagcgccgtc tcttccgcat cggccgatgt cggctctgcg gcagagagtg
     1801 cttcgtccgg cgaggccgga gaagcgtccg caccaggggg cgggggcagc acggtgccgg
     1861 ggtggtcctg gaggccgctc ggcggctcgg gacacggcgg cggcgtggga atcggggctg
     1921 acgatgtccg gtggtccggc cggtgcggca ggctgtccgc ccagccccgg ccgacgggtt
     1981 tctccgtggt gccgggggcg ggatccgatc cgctcggtac gaactcggcc cgccagacgc
     2041 cgccgccctg ccatcggtcg tccaggctca gccggacgcc ggacggaagc agccctgtgg
     2101 cctcctcctg ctcgcgccgt gcgtagtcgg acaccacgga gttggcgtgg cagacggcca
     2161 gtggatagtc cgtgccgtgg agctggtcct gccattgcgg atgcgagcgc agcgcggcgc
     2221 cgagcgcggt gtagaccggt ctgggcggta tagccatgat ccggcgcccg gcccgtggta
     2281 tcgcctggcg taccgtcgaa tcagccagcc gggccaggtc gtcgcggccc agcggcccgg
     2341 gaaccgccag cctctgggcc agcgacgccc gagtgaaggc gtaatccccc cagacccgga
     2401 cgccgctcag ctccgccaga gcttgacgca aggttctcat cagccctttc acggcggtca
     2461 gtaattcggc gcccccgcct cccggcgcga gcaatgtcgg caacggcgtt ggcaccaagg
     2521 cgctggtgag ctggtccctg ccgcttgtga ccagatagcg cgcgtagtgg tcggcgtcgc
     2581 tcaggtccgg gtccgcccac tcgtaccgtg cctccacgac gaggtgcccg aagtcgtctg
     2641 tgcgtccacg gcgacgcaaa cgctgcagac gtgccctcgt gggagccagg tcctgcccga
     2701 atgcggaggt gtcgaatacc agtcgctcgc gcagcacggg cacctcgtcg ggagcgagga
     2761 ggccaggtcc ccgggcgccg gccggggcgc cggacagcca gtcgggagtc tcgccgtacg
     2821 ggccgaggcc ggcgtgggca ccctccttgt agacgatctc cgcgggcagc aggtctccgc
     2881 ccgtacggat attgatcatc gcgccgaccg gcaacgcctc cagccggtcg ccgagggcga
     2941 ccgacggaaa gtcctcgaag tccaggggac cgccgacata gccaccggcc tccacgtcgt
     3001 aaccgaagta gacggcgttg aaagccacag cagtgtgcac cggggccgta cggtgggcga
     3061 tgaccgcggc cagataggcc aacagggcgt cctgcgcctc tggttcacag gcgtccaggc
     3121 cgctgagcat gtctcgcgtg atcaacggtt cgttgtcata cggacgccat acaccatcgg
     3181 ctacatgcag cgcactcgtc atccggtttc cccctcccgc accgccgggt ccccggtgct
     3241 cccggatggc atcacgcgcc accatttccc cgacgacgtc acacgcctgg cctgcgccag
     3301 ccgctcgatg ctctcctcga cgccgcgcaa gggaacgtcc gcgtgcgctc cgaaataccg
     3361 actgccggtg agaccttgtg gaaggcgtac gcgccggccg actttcggcg agtacgagct
     3421 gtcctcgccg cgcagtgctc gccagacgct tcgtgcgtgc actccgcgtg gtactgccca
     3481 gatcagccgg tacacctgtt cgtccagccg ccgcagccgt gactccggca gagcgctgct
     3541 gtcgatcggg cggggcttcg gggtgaggag ggccttcgcc gataccggca tggtctcgcc
     3601 tgccggccag tccggcctgc cccagcaagc gccgcagcgg ttcgactcag tggtgcagca
     3661 gccctcgggc aactcggtca caccgaagta gtcggcgaac ttgcggtgcg cgcaggcggc
     3721 cgagtcgtcg aagaagtcgc gcagccgggc gatctccgca gccgcccgcc tggcctttcc
     3781 ggacatggcg gtcaagaagt ctaccggcag ctcggagcgg tggaccgcga ttccgctgac
     3841 ccagtgccgg ctcggcgcgg ccgagacgtc cagcagcccg cggtcgtgca ggtcgctgag
     3901 caactgccag gtacccgcag ggccttccac cagctcccgg tatccggcca cccggaccgt
     3961 cagcagaccg tccagtgcaa ccacgtcgag ccgtgcccgg gccagacgca gtgctggcga
     4021 ctgcgactca gggagggcgt tcaccacctc gagaatctcg aggacgaccg actcctcatc
     4081 gtcctcgggg cacagctcac cacgccgtac cttgcacaac ggtggaaagt ctccgtggtc
     4141 gctgaccctg cccagccggg ccaggtggct gaaggcccgc accactcccg ccacgtaggt
     4201 gtccgtcaca cgcgccgaac gcgcttcctg gatgcttatt cgtcctgatc gcgcatcctc
     4261 gccgatcagc cggtcggcga cgtcccgggc atccagcacc cccttgcagg ccagcaccgc
     4321 acgccccatg cgcctgacga gctcggggtg cagatcctgc ccggtcatga aggcgactgt
     4381 gcgcaacccc ctggaggtca gcagagccag agcagtgttt gccggagccc cgggctcgac
     4441 ggaggaacca cttcccgcga catctcggcc ggcccgcccc aactgttggt agagcgaagc
     4501 cagatcggtc ggagccgaca cacagaacac ggtgcgcacg tcatcgcggt cgatgcccag
     4561 cccgaaggcg gaggtcgcca cgacgaccaa gggggcgaat ccctcctcgc ccgagcgggg
     4621 tgcctcacgg aactccgtca tgactgccga cttctcggcc tgcgacagcc tgccgtggaa
     4681 gcggcgtacc cgaactccca ggtcaccgac gtactcctgg aggtaggcgt ggagcgcggt
     4741 cacctccttg acagtgaggc agtagaacac ggcatgccct gtcaacgcct ccaggacgtg
     4801 ccgggcgaga ccggccacca cggcagggct cgactggttg agggagcgcc ggaacacggc
     4861 gagctccggg cggatggggt tctcacgtac ggtcaccaga ccgccgtcgt ccaccggcct
     4921 cgtggcttcc cggcgggcag cctcgctgtc cggaggcgga gagtcttcgg gtacttcgaa
     4981 gactccggcc cgaaggccgg cgtgcacgac gtggttggcg gtggcggtca aggcggtcac
     5041 cggaaccgcg tggcagcgcc gtagctgtcg gaggaattgc tcgacgcgct gcatgctggg
     5101 ccggaagtcg tcccactgaa ccatggtgtg cgcttcatcc agcacgacgc ggctgagaac
     5161 gcccgcctca gctgcggcac gtatcagctc tcggaagcgg cgctggcaga gtcgttccgg
     5221 actgacataa acaatcttga tgccgtgatt cgcccgcccc agcagctgat ccgccacctc
     5281 tgttttgccg gctctgctgc tcgactcccg cagcggtgcg atcagcgccc gaacagcacc
     5341 gccgatcgat cggttgagct ccagcgcctg atcctgcatg agcgccacaa gaggactgac
     5401 gacgagggtg acgcccggca gcaccagtgc agggagctgg aatgtgaagc tcttgccgta
     5461 cccggtcgga aggagaccga gaacgttgcg cccctgcgcc accccttcga taacggtccg
     5521 ttgggcgggc ttgagccgga aatcgctcgg gtcgtccatc aggcggagca gcccggccac
     5581 ctccgaggcg cgccggagga cctcctcttg cagctgatcg tcggctgcca acttcgagac
     5641 gtcttcgacc gacagctcga gctgcctgat gcgaagcgtc tggggcagca gggtgtgccg
     5701 ctgcagagcg ccgggctctg acagctcttt cccccgttgc ggggagagca ggccgtgccg
     5761 tacgaagaac gaccagatcc gggcccatcc ctcggtcatg gttgcgacgt tggcggcacc
     5821 tggttccccg gtatgcggat cggtgcggag caggccctgg tcgaggctcc ccagaaaggc
     5881 ccggcgatag gcgcggcgca aggccgtgtg cccggccagc ttccggtcgc tgatcacgac
     5941 gacgccccgg tgccgctcgg agcggatcag gcgccccacg gcctggcgca actgcagagc
     6001 cgcgagcgga atgtagtagt gctccgttgc atgggcatcc gggtcctccc ggcctgcggc
     6061 ttcggcccgc gcgcgtacgg cagtgcgcct ggcctccacc agtggcgccg cgaaaggcgc
     6121 gaagggcagc ttgttgatcc agacgagccg taatcggtgc tcgtccgaga catccacgcc
     6181 ctgccacagg cctttggtgc cgaccaggaa tccgccccca ctgccggggt cggtgaactg
     6241 ctcgaatgcg cgcgaattgc ccagtgcgag cgcgttgacc acgtgcgtgg gatcaccacg
     6301 ccgatgcagc tcctccgtca ggaattccgc gatcccggct gccgtcgacc gtgcggtggt
     6361 caggaccagc gccccaccgt ccgcgctccg gccccgtgtg ccgggtcgta ccagctccgt
     6421 ggcgtagccg ccgagctggt gcgccactgt ccgcatggct ccttcctgct gctccgccca
     6481 ggacgggaag tccgagaaac agatcagctc cgcctggcga cgcaggtcga aaggggtgtc
     6541 tacacacatc gccgcgagtc cggccagccc gaggcgcccc atgatgtagt cccagctgcc
     6601 cgcgacgcgc agtgttgcgg acacgtagta cgtgcgaggg aacaagttca ggaaccgcct
     6661 ccaccgggca tcggccggca gttccacggg gctggaagag atccggaagc gatagtggcg
     6721 aagaccggtg agggggatgg cgagctcttc ggcgtagacg atccgattgg gcagcggtgg
     6781 gggaagcagg ccggcctgag cgtcgagtac accgtcggtc agtaaaacgt cgtccgccgc
     6841 gtcatctgca tcggtctcgc tctcgggctc ctctccctgc tcttcctctc cttcgacggg
     6901 ggccacgggt tcgacgtccg ggtgggcacg gccggacgtg tgcccctccg acgggagtgc
     6961 gccgagtacc tcctgagcgt ccgacagcag tgactcggcc gtttcacgca ggtcggcgac
     7021 ctgggtctgc atcaccgaga gcgcgtccat cgagaagaag tcgagcgcgg aggcgtgagc
     7081 ctgcgcgaag gcggccagcg cccgctccaa tcggagggct gtcgaggaca agcgacggat
     7141 gagcgcgatc aacgcccgga cctgtccgag tccggagctc ccgccgtagg gactggccag
     7201 ggtgactgag cgtgcgccga cgacggatgc atcctgcccg cccagcgcgt cgaacgcgcg
     7261 gctggcggcg tgggggaggg actcgtggtc gaggagcgtt tccagttcca cgacagcgtg
     7321 tgccacgcgt tcccgagccg gccctgatgt cgcgtccttc aaccaggtac gggcggacgc
     7381 ggcgagttgc tccaccgcgc cgtagtccag ggaaacagtc aaggctgagg tggcggcgtc
     7441 ctcgagcagg tgggcttcgt ccacgatcag catcgtctcg ccagggagtg accgcagatc
     7501 ctccagatga gccaggagca cggcgtgatt ggccagaatc agccggtggg aggcgattgc
     7561 ctcgcgcacg ctgttcgtgt gcaccgccag tggtgtggcc gccgtggccg cgtaatcccc
     7621 gtcggtttgg gagagagact ggagccagag ggccagtgtc ggcccgcagt atgcatcgag
     7681 gaaggcgggc acatcgacgg agtccaccga gcgggcagtc cacatggcgg gggcagacga
     7741 agctgcaacc agtcgcaaca ggaggaaaat tcccagttct cggaacctcg tgtgctcgac
     7801 gaaccgtgag cgggtacggg agaccgtggc cgtaccgagg gcggtcgcgt cggacagagc
     7861 agcggccaag gcgcgcaggg agagccggtt ccctctgccc ttcaccaggt cggtggctga
     7921 caggaggccg ggcatggcac ggctgagaat gtcgacgtcc cgagccatct ggctctgcag
     7981 atgcttggtg taggtggcta tgacgacgct gcgggtttcc ccgccgccga gccagtccat
     8041 cgcggcggcc aggacggcga agctcttccc cgtacctgtc ggtgcctcca cgagggcggg
     8101 gataccggcg tcggcccagg agtgcaggcc cgcggtcatc tgctgctgcg ccggccgcga
     8161 acgggcagca gcgccatgga ctaccttggc cagtgctccg ggatcgaccc ggccatcgga
     8221 gcgcagctgt cctggtacgg cgagcgctct tcggcctggc gctgcggcgg gtggtccgct
     8281 acgccgtgga gtgtgatccc ggagccagcc ggctagcgcg gccgagaccg ttggccggtc
     8341 ccagatgaca agggggtcga ttgccgctgc tgggcccggg gccgcccggg caaggtcgtt
     8401 gagcagtctc caagcagggg aatcagggca tgcggctgtg acgagcgcgc aaaggttcat
     8461 gggccgggaa gccagttcgc cggcgcatcg ggacaggaac cggaccaaca actccgcgtc
     8521 gtcggctgcg ttgtgccacc gaaggcccga acggtcgacc tcctgggcat cacagagcag
     8581 ggcgaggcgg tggctgcggg cgagaggcca caggcagtgt gccaagtaga gcgagtccac
     8641 gcggtccccc gggaccgggg gcagatcttc gcgttcgcat gcttcgtcga gaagggggaa
     8701 gtccgctgcg attccgttgt gcgcgaccag cacgtccgtg gtggtgcaga actcacggac
     8761 gcgctccagt gccgcacggg gcaccaaggc ccgggcctgc tgttgctccc ggagtccctc
     8821 gtcgtgaatg gcccagtcat cgtcgggcaa ggacaggaag acctgcagcg acggctgttc
     8881 ctcgatccag gctgcatccg ttcccgtccg tacggcaccg atctggaaga tgcggcggtc
     8941 cacatacggg ggcgtggctg tcgtgcgcac cacactctcg gtgtctatgg cgacggcacg
     9001 tatgccgcgc cgggcatcgg gttctccgct ccgggccgct gcctcttgaa gtcccgcgcc
     9061 ctccccggtg aacagcaggc cgtcacgctc gtgtaactgg cctgcggaca gtgcctgatc
     9121 gaggaggccc gccaggcgct ggggcggcac tcgcttgaag cggtcccgcg ctgctgcgat
     9181 cagatcttcg acggtgatgc cgcggggatg cgcggccacg agttggatca agggggcggc
     9241 agcggccgac gctcgcttgc tgctggacgt tcccatgaat catcctcggt ggtgccggag
     9301 ccgggcggag gtggaggtcc gaaacggcat agtcgtctgg aacttgacta ttgtgctgcc
     9361 gtaaccgtct gttgtgggag tgttaggtca aaacaagtga cattggttgg gcctggaccg
     9421 gaagtaaccg cagagaccgc ggtgggcagc gaggcaacgc tgcatcggtc accagcgacc
     9481 gcatccgatc ggcatcgatc caccgctggt tgaggccgaa gcgcgttccg ggtacagctc
     9541 ggcttcgcac cctgcaggcc cgtcgcctct ctctttcctc tcgcgaccgc atgggactgc
     9601 gtgggggctc cgacgccccc acccgaaccg cacagcgaag tttcatccgc cccgtcatcc
     9661 gttttagttg acaagctgcc tacggtttgg cgtacgctca ccaggcattc cgttcacacg
     9721 agcggacggc tatcgcggca gtcacttctt gctcagttct tgctcggccc tcgaccaact
     9781 cctgcgcacc acctgccaag tgcacgctca gcggcactcg ctcctcgctc ggcgtttcga
     9841 ccagcacctt tgctttcggc tcggccccgc acgcccttgc ccggcaaccg tgcggcgttt
     9901 gttcacctcg cgtcagctca gcccggccca cccctgcccg gcacgtccgg ccctcgcccg
     9961 gtctcgtgga catggaggtc ccagcacgat gaaagccctg atgttcgaag ctcccgagcg
    10021 agccgtgctc accgagcgcg cgatgccgga gccggccccg ggagaggcgc tggtgcgcct
    10081 cgcgtacaac tcggtctgcg gcagtgacct ctccttctac aagggggtct ggcacggttc
    10141 cacctacccc gtcgtgccgg ggcacgagtg gagcggcacg gtggtggacg tcaacggggc
    10201 cgacagcggg ctggtgggtg ccgatgtcgt cggtgacctc acctgttcct gcggggcctg
    10261 ccggcactgc gcggagggca agcccacgct ctgcggcgac ctccaggaac tcggtttcac
    10321 tcgggacggc gcgtgcgccg agtacatgac cattccggcc gccaacctgc accggctgcc
    10381 cgcggggacg tcgctgcgcg ccgcgtgcca ggtggagccg ctggccgtgg cgctcaacgc
    10441 cgtggaccgg ctggccgtgg ccccggggga gaaggtggcc atcaccggag ccggaggcat
    10501 cggcctgctg ctcgcgctgg ccgtccggca gcgcggggga gaggtcaccg cgttcgccga
    10561 gcccgtcgcc gagcgcaggg aggcggccgc ctccctgggg gtggccgcca ccgtcggggg
    10621 agcgccgggc gacctcgtcg ccctcgtcga gaagcacccg gaactgcggc ccgatgtcgt
    10681 cctggaggcg tccggctatc cgtcggccgt acaggaggcc atcgaggctg tccgctctgg
    10741 cggacgggtg gggctcatcg gctaccgcgt ggaagagacc gggccgatgg cgccccagca
    10801 catcgtcatc aagatgctga cgctccaggc gtccatgggc cccggcaccc ggttcggcga
    10861 ggcgatcgag ctgctgtcct cgggcgccgt cgacgtggag gccctgctga gccacgagtt
    10921 cgccctggag gaccacgcca gggccctgga cgtggccctg cgccgcgccg acgggaacac
    10981 ccgctcgttc ttcaacctcc gcacttgacc gcaccggccg gttccgtcgt atgcccgggg
    11041 gcggtccccg ccgcccccac cggtcccatg ctcaggaagg acgatccgat ggcgcaatcc
    11101 ctggcagtgc aaggcggcag cgcggtacgc acccggccct ggcccctgtg gccccggccc
    11161 gcggccggcg cggccgaggc ggtgcagcag gtgctctcct cgggccgctg gtccatcagc
    11221 gggccctacc ggggcaccga ctcccacgag cggcgcttcg cccgcgcgtt cgccgcgtac
    11281 aacggcgtcc cccactgcgt acccgccgcc agcggcaccg ccagcctgat gctggccctg
    11341 gaggcgtgcg gcgtcggcgc gggcgacgag gtcatcgtgc ccggcctgtc ctgggtggcg
    11401 tccggctcca ccgtcctcgg cgtcaacgcc gtacccgtct tctgcgacgt ggacccccgc
    11461 accctgtgcc tggatcccgc ggccgtcgag gccgccgtca ccgagcgcac caaggcgatc
    11521 gtcgtcgtcc acctctactc ggccgtcgcc gacatggacg ccctcaccgc cctcgccgaa
    11581 cgccactccc tgcccctgat cgaggactgc gcgcaggcgc acggcgccgc gtaccgcggg
    11641 gtgaaggtcg gtgcgctcgc cacggccgga accttcagca tgcagcacag caagatgctc
    11701 accagcggcg agggcggcgc ggtcgtcacc cgggacgccg acttcgcccg ccgggtggaa
    11761 cacctgcgcg cggacggccg ctgcctggcc gggcagcgcc cggcgcccgg cgagatggag
    11821 ctggtcgaga ccggcgagct gatgggcaac aaccgctgcc tgtcggagtt ccaggccgcc
    11881 ctgctgaccg aacagctcaa ggaactggac ggccagcacg cggtccgccg ccgtaacgcc
    11941 gctctcctcg acgacctgct cggcgagtcg ggttacgtcc ctcaggagac ctccgagggc
    12001 accagcaccc gcacccacta cacgtacgcc gcccggctgc ccgaaggcca cctcacccac
    12061 gtcggcgtcg ccgccgtggc cggggcggtc agcgccgaac tgggcctgac cgtcgcgccg
    12121 tcgtacgcgc cgatcacccg caaccggctg tacgacccgg gcagccgccg gcgctacgcg
    12181 ctcggtgtcg agcaccaggc gctgaccgac cccaagcgct tcgagctgcc ggtggccgag
    12241 gccgccgccc ggcgcgtcct caccgtgcac cacgccgccc tgctcggtga cgagaacgac
    12301 atgcgcgaca tcgcggcggc gttcggcaag gtcctgcggc acggcgccga cctgaccgaa
    12361 tgagaccgca gcaccgcctt gggaccgtcc cgcgatccgc cgcagaaatc ggggtgaaca
    12421 tgcacgtcac ggccatcacc atggaagacg ccacctttcc ctaccggctc ggtaccgact
    12481 gtgccgaaga gatcgtcgcc cggctgggcg accgcgccgc cagccgctat ctcgtggtct
    12541 gcgacaccac ggtggccgcg ctctacgggc acgacctcgt ggcccgcctg gagaaggacg
    12601 ccggtccggc ggtcctgctc acccacgagg cgggcgaggt gcacaaggac gtcaccaccg
    12661 tcggcgcgct ggccgaacag gccctgggcg cgggtgccga ccggcgcagc atcgtcgtgg
    12721 ccctgggcgg cggcatcacc gggaacatcg cgggcctgct ggccgcgctg ctcttccggg
    12781 gtatcgccct ggtgcacgtg cccaccaccg tcgtcgccat gctggactcc gtgctctcgc
    12841 tgaagcaggc ggtcaacgcg agtttcggca agaacctcgt cggcaccttc taccagcccg
    12901 ccgaggtcct cgccgatacg gcgatgctgc gcaccctgcc cgtacgggaa ctgcgttccg
    12961 gcatgggcga ggtggtgaag aacgccctcg ccatccgccc ctccatgacc gagcggctgg
    13021 ccggactgct gcgccccgac gggcgctacg acgacgacgc gctgcgctgg atcatcgccg
    13081 agagcgtcgc cgccaaggcc gacgtcaccg gcgccgacaa gcacgagcgc cgggacggcc
    13141 tggtcctgga gtacgggcac accgccggtc acgccatcga gcacgccgcc cgcggcgagg
    13201 tcgcccacgg cgcgggcgtc gccatcggca tggtgatcgc cgccgaggtc tcgcaccggc
    13261 tcgggcacgc ctccgccccc ttcgtcgccc tgcaccgcga actgatcgcc aaggcgggcc
    13321 tggagcacgc cgtaccggcc ttcgtgggca ccgacgacgt caagaactgg ctgacgtacg
    13381 acaacaagcg cggctacctg gactgcgagg gcacctccac gcccatggtg ctgctctccg
    13441 gccccggcca gccgctgcgc accggcggga tgcccctggt acccgtaccg ctcagtgtgc
    13501 tcaacgagac cgtggacgcc ctggccggcc ccggccgtac cggcgcggac caccgggcgg
    13561 cggtccccgt ctgacgcgcg gcggcccgtg cgccgccccc gaccgctgtc ccgatttccc
    13621 accgtccgtt cctcctaggg gagttctcgt gcgcgtgctg cggctgaccc cgttcttcca
    13681 ccacgaccag gtcgagaact ggcccgccga gtacgacgcc gtcggcggga tgcaggtgca
    13741 gatcctgggc ctgtcgcggg agctggccga ccgcggcgtc gaccagcagg tcatgacggt
    13801 gggcttcccc ggtctgcccc ggtggcgccg ggaccggccc ggcctggtgg tgcggatcac
    13861 ccgcgcgccg ctgccgcggc tgcgttcgga gctgaccgga ctggtcggcc tcaaccaggc
    13921 gtggctgctg ggggccctgg cagcctgcgc ccggctgggc cgccggtggc gccccgacct
    13981 gatccacgtg cacgccgacg gacagctgtg ggccctgctc gccgggccgc tggcggcccg
    14041 catcgtgggc gccccctact gcctgacgct gcactgctcc cggctggccg tgtacgaacc
    14101 gatgtcccgc ctcgaccggt ggcagcaccg gctggtgcgc gccgtcgaac gccacaccct
    14161 gcggcacgcc gccggggtgt ccaccctgac cgcgcgcacc gccgatgtcg tggcccgcgc
    14221 cctgccgatg gaccgctccc tcatcgacgt cgtacccgac tccgtggggg aggtcggccc
    14281 acggcccgaa gccgccgctg ccttgcgccg ggacctggac gtgcccgaag gggcgcccgt
    14341 gatcggctac gtggggcggg tggcgcacga gaagggctgg cgcgacttcg tggccatggc
    14401 cgcgcggtgg cgtgccggtc ccggggccgg ggcggcggtg ttcctggtgg tgggcgacgg
    14461 gccgcagggc gaccggatgc gcaaggccgt cgccgacgcg ggcctgaccg accgcttccg
    14521 gttcaccggc ttcctgccgc acgccgagat ccccgccgtc atgacggcac tgagcgtcct
    14581 ggtcatgccc tccgcccacg aggaactggg cggcagcgcc atcgaagcca tgatgtgcgg
    14641 cacccccgtc gccgggtacg ccgtgggcgg cctgcgggag accgtcggcg gggtcacccc
    14701 cggcctcctc gtgccgcgcg gcgacgtcgc cgcgctcacc cgggccgccc gcgacgccgt
    14761 acaggaaccg gaacacgtac ggcagtcggt cgccggggcc cggcagcgcc tggcgtccga
    14821 gtacggcagc ggcgccgcga ccgaccgggc gctggcgcac taccgccgcg tcctgcgcac
    14881 gaagggggcc gcacggtgag gtacgcccgc accggatcgc tgtggcgctg cctgcgctac
    14941 ctgcgtccgt acggctggtt catggccggg gccttcggca ccgccctcgg cgcgatgctg
    15001 gccgggctgg ccatgccgct ggtcctccag cgcctgatcg acgggcccct cgcccaccag
    15061 gacatggggg cactgccggg cctgatcgcg gggttcgcgg tgctcggcgc cgtcgaagcc
    15121 gtcctgctgg gcgcccgccg gctgctggtc gtacgcccgg cgacgcatct ggagaccacg
    15181 atgcgcgccc gtctcttcca gcacgtccag cggctgccct cgtcgttcca ctcgcactgg
    15241 agctccgggc agctgctgtc cagaacggtg tccgacgtca ccgagatcgg ccggttcttc
    15301 gcgttctccg ccgtgtacct gctggtcaac gtcgctgccc tggtggccgg gctgggcgtg
    15361 ctggcctggc tctcacccgt actcgcgctg gtcgtgctgg tcacctacct gccgatggtg
    15421 gccgccaccg tcttcttcga acagcgcttc cacaccgtgg cccggagcgc gcaggagcag
    15481 agcggcgacc tcaccaccac ggtcgaggag tccgtcgcgg gcatccgggt gctcaaggcc
    15541 ttcggccgct gcccggagac cgtacgccgc ttcaccgcgc aggcccgtgc cctgcgcggc
    15601 acggaactgc gcaagatctc cctgaccgcc gccctgtggt ggaccgccac cgccctgccc
    15661 gaactgggca tcgtcgccct gatggggtac ggcggataca gcgcggccac cggccagctc
    15721 accctgggcg tgctgatggc ggccatcacc gtcgccacct acatgcgctg gccggccgac
    15781 accctgggct ggctggtcgc ggacgccagc accgccggcg ccgcggccac ccgctactgg
    15841 caggtgcgcg acatccccct cgccgtcagc gaccccgcga cgccccggcc cctgccccac
    15901 ccgctgcgcg gcgaactgcg gctggagaac gtccactacc gccaccccga gggcaaggac
    15961 gcgatcctgc gcggcatcga cctcaccgtg ccccccggca ccaccctcgc cctcgtcggc
    16021 gccaccggct ccggcaagag caccctggtc tccctgctga cccgcctgga cgaccccacc
    16081 gctggacgcg tcaccctcga cggcaccgac ctccgcgacc tcaccctgga cgccctgcgc
    16141 tcggccgtca cctgcgcctt cgacgacccc gtcctgttct ccggcaccgt ccggcacaac
    16201 gtcgccctcg gcctgccgga cggcacccgc gacgacgggc gcatccacgc ggcactgcgc
    16261 ctggcgcacg ccgacggctt cgtcgccgcc ctgcccgaag ggctggacac ccgcctcggc
    16321 gaggagggca cgggcctgtc cggcggccag cgccagcgcc tcgccctggc ccgcgccgtc
    16381 ctccccgggc ccgccgtcct cgtcctcgac aacgccctgt ccgccctcga cgtgcacacc
    16441 gaacgcgagg tcgaggccgc cctgcgcacc gtgctgggcc aggtcaccac cgtcctcgtc
    16501 gcccaccgcc cggccaccct ccgcctggcg gaccgggtcg cgctcatcgc cgacggacgc
    16561 gtggccgcca ccgggaccca cgacgagctg atggccaccc acgccgccta ccgcgacctg
    16621 ctcgaatccc cggtgaccgg ccccgcggga gcggacggcg ccccgctccg cggcacagca
    16681 cggaaggtcc aggcccgatg accgacgaca ccgccacggc cacctcacgg ccgcggaccg
    16741 aggacctgcc cggcggaccg gccgacaccg actcggaccg gctgctgcgc gaccgccgca
    16801 accgcctgct gcgcaccttc ctgcggcccg aaaggcgacg gctggccctc gccgtcggcc
    16861 tggccctgct ggagaacctc agcagcctgg tcaccccgct gctgatcgcc gccgccatcg
    16921 accgcggcct gcccgcggcc acggacggcg actggggccc gctcaccacc tacgcctccc
    16981 tggccctggg ggcgggcctg gccaccgcca ccctcaagta cggcttcctg cgctactccg
    17041 gcgccatcgc gcagagcctg ctgttccacc tgcggcaccg cacgttcgcg cacgccctgc
    17101 ggctgccgct gtccttccac gaggcgtccc cttccggcag cgtcgtcgcc cgcctctcca
    17161 gcgacgtcga atcggtcgaa gaggtcctgg agatgggcct ggacgggctg ttctccgccc
    17221 tgttctccat ggtcggcatc atcgccgtga tgatctggct ggacctgccg atggccgccg
    17281 tcgtcctcgc gctcttcctc cccctgtacc tgctgacccg ctggttccgc aggcgctcac
    17341 gcgccgccta ccggcgcacc cggggcgcga ccgaacacgt cgtgcggcac accggcgagg
    17401 cgtacaacgg catcaaggcc gtccaggcgt tccgcaagga ggacgccaac gccgccgaac
    17461 tgcggcgcct ggacagcggc tacgccgcgg cgcgcgccgc ctccggccgc gtcagcgcct
    17521 tcttcagcgg cggcgtcaaa ctgatcggca acctctcgct caccctgctg atggccttcg
    17581 gcgccgtccg catcgcccac gggcagctgg aggccggcac cctggccgcg ttcctgctct
    17641 acgtccaccg cctgtacgac cccatcgacg aactggcctc cttcgccaac gccttctccg
    17701 cggcctccgc cggactggaa cgcatcggcc tgctcttcca cgccaccgac accctccccg
    17761 gaccggaccg gccggtaccc ctgccgcccg cggccgcccc cggccgggtc cgcttcgagg
    17821 acgtacggtt ccgctacgcc cccggatcgc cgtacgtcct ggacggcgtg agcctggacc
    17881 tcgtccccgg gcagaccgtc gccctcgtcg ggaccaccgg cgccgggaag tccacgctcg
    17941 ccaagctgct ggcgcggctc tacgacccgg cggccggccg gatcaccgtg gacggggtgg
    18001 acctgcgcga cgtcgccgat cccgaactgc gcacccacat cgccatgatc acccaggagc
    18061 cgttcctgtt ctccggcacc gtggcccaca acatcgccct gggccgcccg gacgccaccc
    18121 cccaggagat ccgccaggcg gcacgggccg tcggcgcgca ctccttcatc accggcctgc
    18181 ccgacgggta cgacaccgac gtacgcaaac gcggagccgg gctctccgcg ggccagcgcc
    18241 aactcgtcgc cctggcccgc acgatgctcg ccgcgccgcg cgtcctcatc ctcgacgagg
    18301 ccacctccag catggacgcc ccctccgagc gcgccgtcca caccgcgctc gaccgggtgc
    18361 tcacgggccg caccgcactg atcatcgccc acagcctgac cacggtcgcc atcgccgacc
    18421 gggtgctggt gctggaggac ggcgccgtcg tcgaggacgg cccgcccgcg gtcctcgcca
    18481 ccggcgacgg cccgttcgcc cggctgcacc acagctggct gtcggccacc gaccggcgcg
    18541 cccaccactc ctcggaccac tgacgaaagg catcgcatgg agcgcctgcg gggaccctcg
    18601 ccgctggaga acaccgccgc ccgccacccg gcaccgctcg gccccgccca ccgcgacggc
    18661 ctcggccccg gcaccgccga ccgcgtgtgg gacgtctgcg tcatcggcag cggcgccagc
    18721 ggcgcggtgg ccgccgaccg cctggtccgc cagggcctcg acgtcctcat gatcgaggag
    18781 ggcttccggc tcgcccccca cgtcggcctc gacgaggccg agtccctgag ccgacaggcc
    18841 ctcgcccgcg acgacgaggg caactggacc gacgagggct ggccctggac cacctccaac
    18901 ctcggcggcg gcaccgtcta ctacggaggc gcctccttcc gctaccggcc cttcgacttc
    18961 gaccccggcg aactcgtcca caccgacggc gtggacgtcc gctggcccta caccctcgcc
    19021 gacctcgcgc cgtactacga agtgctggaa cgccgcctcg gcgtgtgcgg cggcgacgcg
    19081 ccgggcgccg cccgcggcag ccgccacagc cggggccccg cccaccagcc gtccccggcc
    19141 gcccgcgtcc tgcgcgcggc gggcgaatcc ctcggctacc ggccctttcc gacccccctg
    19201 gccatcaacc gcgacgccca cgacggccgg gcggcctgca accgcgactc cctgtgcgtc
    19261 agccacctgt gccccacggg cgccaagggc gacgtcgtct cggtcttcct cgcccccctc
    19321 gccgcccacc ccaacttcgc cctgcgcacc ggggtccgcg ccctgcgcct ggaacaggac
    19381 cgctccggcg aggccgccgc ggtcagctgc ctggaccggc agacgggcca ggcgcacagg
    19441 gtgcgtgccc gcgtcttcgt cgtggcctgc aacgccatcc agagcgccgc tctgctgctg
    19501 cgctcccgta ccccgtactc acccgacggc gtcggcaacc actcccggat ggtcggccgc
    19561 ggactgtgca tgaagctcag cgagtacgtg agcggcacgg tggacgccga gcccgcggtc
    19621 ctcgcggacc cccgcaccaa caccgggccc ttctccaccg tggccttcct cgaccactac
    19681 ctcgacgccg actgccccgg cggcttcggc ggtctcatct acgagtccaa gcgcgaccag
    19741 cggcacaaac tcgtccacga cgccctggaa ctgcgggtcg agacgatcct cgccgaccac
    19801 cccagcctcg acaaccgcgt gggcctgtcc ggccgcctcg acgaggacgg catgccggcc
    19861 gtggtcatcg actacacgcc cgacccccgc gacctggacc ggctgcgcta catgaccgga
    19921 cgctgcgaac gcctgctgca cacggccggc gcccgcggca tccgccgcaa gcgcaccggc
    19981 ttcgcccagg gcagctccca cctgcacggc acctgccggg cgggccacga cccggcccgc
    20041 tccgtggtgg acgcctgggg acgggtccac tcggcggaca acgtctacat cgtggacggc
    20101 agcttcatgc cgtacccggg tggcctcaac cccaccctca ccatccaggc ccacgccctg
    20161 cgcaccagca gggccatcgc ctcccacctg gcggccgacc gcgccgccca tgtgtgaccc
    20221 ggcacgcaag aggagacacg gatcatggac acacctgtcg tctggccgcc gcgcacgcgg
    20281 cgcatccgca cctaccgcaa catcgtcatc gacggcgcct gcaacctgcg ctgcacctac
    20341 tgcgaagtca aggccatcaa ggtcgaccag gtcgccacca acgcctccct ggacaagatc
    20401 ttcgagcggt acgagcccgg caacacgctc ttccgcgtgg agtccaacgg cgagatcgcc
    20461 ctgtacccca agatcctcga ccacctccag ggccgcgccg ccgacggctg gcacatcgag
    20521 gtgctgagca acggcacccg cctgccgcgc tgcctgaagg gccgcgagaa cctgatgtgg
    20581 gtcttctccg tcgacggcca caccgcccgg atgaacgcca aacgcggcat gtcccaggaa
    20641 caggtcgacc gcatcctgga caccgccgtc gagctgggcg ccgaactcca gatggtctac
    20701 cacgaccaga gcctggagga ggtcaacgag ttcatcgacc tgctgtccgc ccgcaactac
    20761 accggcctgc tgcacttcat gccgctgctg gccttcaagg gccgcccgct gaccgtcaac
    20821 ctgcgctacg aggacctgca ccccgccccg ttcctcgccc cgtccgagta cttccgccgc
    20881 tggaaccaca tcttcgagac cggcaagcgc gacgcggtct gcgaccagat ctccaacggc
    20941 tacaactact cggtctccga cgaccgcatc gagatggtca agtgcgactg ctactcggtc
    21001 cccaagcacc tctaccacga cttcggtgac atacgggagt tcgacaactg gccctgcggc
    21061 acctgcatcg ccaaccagga gttcaacaac tcccgcccgc gcatgcaggt ccccgagggc
    21121 cggataaccc tgcccctcgt atgagcaccg cacagcggtt cgtgctggtg cgccacgccc
    21181 aggccgccgt caacatcctc ggcgacgacg acctcatgac cgcccacgac accgacgccg
    21241 acctcacacc gctgggggag gagcaggcac gggcgctcgc cggccacctg gcgggcgacc
    21301 gtgccgcctg gcccggaccg cccggcgcgg acgcctaccg cctctacacc agcccccagc
    21361 ggcgcgcccg gcgcacggcc gagccgctgg cccgcctcct gggcctggcc gccgtcaccg
    21421 acccgctgct ggccgaggcg cactccccgc cccgcttccc gcgacccctg cgggtacggg
    21481 agtgggacgc cgtcctggaa gagcggctgc gccgcaccga cgcggagatc gccggtgtcg
    21541 agagctggac ggcgcagcgc gcccgggtcc ggcggttcct gcgcgaacgc tgcggggacc
    21601 ggccgggcgc gggcttcgtg ctggtctcgc acgccgagac catccaggca ctgctgctgg
    21661 aactcctggg cctggacgac tccgtcctgc tcgcggcccg cttcaaggtc agcaacaccg
    21721 gcgtgttcat cgtcgacagg accgtggacg cccccacgga cggaacggag cagccatgcg
    21781 gctacctggt cgtggccaac tcgaagacgc acctggcccg gacggcgtga gcggcgcacc
    21841 ggagcccggc cgggcgaccg gctcgtcgcc ggacgccccc cgtgccctgt tcgagatcta
    21901 cgacgagggc ttcgcctgcg acacctgggg cggcgtggag accgccctgt ggagcctggc
    21961 cgaagggctg cgcgccctcg gcgtgcaggc cgacttctac ccctcctcac aggggaccga
    22021 cctcgaagcg ctcgccgggc gggtggcccg ggagcggacc gacgcggtct tcccgctggt
    22081 ggagagcgcc ctgttccgcg gcgaccggtg gcgccgactt cccgcgctgc accggcgcgt
    22141 ggtccgtatc tggcacgacg tcagccacct gacgccggac ctcaccaccc caccgccatg
    22201 tccggcgcac acccccggca cggcaccgga cccggacgcc gggtgcccgg ccaccccggc
    22261 ccacccggac gggcccatgc gcgaggtctt cctgcgcgac ctgccctgga cccgctgttt
    22321 ccccgaccgc gcgtacatcc cctgggccgc cgaccacctg cccgccgagg acctgcgcga
    22381 catccgcggg cccgtcgtca tccagctcgg caagacaccc gtcgaggacg ccgaacgctg
    22441 tctgacccgg ctcctggagg cccggttgcc ggtccgggcg gtgttcgcca cctggtcccg
    22501 gcagggccgg gccgcccggg acctggtcca cgaacgggcc gcgtccggcg atatcgaggt
    22561 gttcgacacc tacgacatcc gcaccgactg gaaacgggtg tacgggggag cgcggctgtt
    22621 cgtgctgccc tccgtcttcc acgagacctt caacttcgcc gcggccgagg ccgtccagct
    22681 cggactgccc gtcgcgaccc tcgccgactg cggggccctg cccggcttcg cgtcgctgac
    22741 cgccgccacc gtcgaggacc tgatggaccg ggtcgtcacg gacggcgcgt cggtccgccc
    22801 ccggccgcgc tcgcggaccg gctgggacga ggtcgcccgg cactacgcgc ggctcatcac
    22861 cacgaccggg gaccgcgccc ggcacgagga ggcggcatgc cggacctgat caccgaactg
    22921 cgcacccacc gcaccctgct gatcgccccg cacccggacg acgtggccta ctcctgcggc
    22981 ggcgcgctcg cggcctgcgc cggagccgcg caggccgtcc tgctgaccgt cttcacccgc
    23041 tccgcctggg cgctgcccaa gcggctgcgc gcggcgggcc cggcggtgat cagcgcccgg
    23101 aggcaggagg aggaactgcg gtactgccgt gcccgggggc tggaacgcta cgtaccgctg
    23161 ggcctggacg acgcgagcct gcgcggctac gacgacgaca cggagatgac ggcggacccg
    23221 gcggccgatc cggcccgcga gcgggtcgcc caagtgatcg cggaggccgt ccgcgacctg
    23281 cggcccggcc tcctgctggc ccccgccgca gtcggcgggc acgtcgacca ccgcctggtg
    23341 cacgacgccg tacgggattc ggcacacgac ggcgtacggc ggctctacta cgaggacctg
    23401 ccctacgccg cccatcaggc gtccgcggac ctggagaaga ccctcacggc ggaacggaat
    23461 ctcgtcccct acacgaccac cgacgtggcg cacgtcttcc aggagaaggt gcgcggcatg
    23521 tacatctacg gcagccagac ggacgaggag tgcgtacgcg aagtgaccct gcac
//
