LOCUS       NZ_LWKZ01000017        21074 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02923 scaffold24, whole genome shotgun sequence.
ACCESSION   NZ_LWKZ01000017
VERSION     NZ_LWKZ01000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02923
  ORGANISM  Streptomyces sp. CB02923
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 27207)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27207)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905005.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:56:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,128
            CDSs (total)                      :: 8,049
            Genes (coding)                    :: 7,904
            CDSs (with protein)               :: 7,904
            Genes (RNA)                       :: 79
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 32 of 145
            Pseudo Genes (incomplete)         :: 128 of 145
            Pseudo Genes (internal stop)      :: 11 of 145
            Pseudo Genes (multiple problems)  :: 22 of 145
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2493
            Orig. end                         :: 23567
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWKZ01000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(294..419)
                     /locus_tag="A6A06_RS43520"
     CDS             complement(294..419)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS43520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274535880.1"
                     /transl_table=11
                     /translation="MLSEVTATRYVTPLREGGSLPGIVEGDDFGTYVMKSSTASG"
     misc_feature    complement(510..523)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(701..715)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            789..1511
                     /locus_tag="A6A06_RS18290"
                     /old_locus_tag="A6A06_39375"
     CDS             789..1511
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642412.1"
                     /locus_tag="A6A06_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39375"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_073762379.1"
                     /transl_table=11
                     /translation="MRFTSGQRLDNGVLEREFTLGEIPGTLWMPESAAPAPLILMAHNN
                     GLPKKEARLVARARHFAAYGYAVAAIDAPGCGDRPRSAADEQARADIRRAMRTGEPTDE
                     ILESFVGPLVEKAVPEWRTTLDALLALPEIGGPVGYSGWTALGIRLAVAEPRIAAAGFF
                     AGGYVPRAQREEARQVTVPLLLLLQWDDEGNPRQRALDLFDAFGAKEKTLHANMGGHTG
                     TPWFEVEDGGRFFGRHLK"
     misc_feature    complement(1643..1657)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.22"
                     /tool="antismash"
     gene            2068..2445
                     /locus_tag="A6A06_RS18295"
                     /old_locus_tag="A6A06_39380"
     CDS             2068..2445
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070123.1"
                     /locus_tag="A6A06_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39380"
                     /product="ATP-binding protein"
                     /protein_id="WP_073762380.1"
                     /transl_table=11
                     /translation="MEYTLPDDAESARWARRLTTAFLTDRRAPAGAREQLDDARLIVSE
                     LVANAAEHGHSACRLRLRVDQGELTVEVQDDSPLPPRTGKLSLWAESGRGLAMVRLLAS
                     RFAVTGDRDGGKTVRAVLAVC"
     misc_feature    complement(2468..2483)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.76"
                     /tool="antismash"
     gene            2663..3088
                     /locus_tag="A6A06_RS18300"
                     /old_locus_tag="A6A06_39385"
     CDS             2663..3088
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357763.1"
                     /locus_tag="A6A06_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39385"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_199930970.1"
                     /transl_table=11
                     /translation="MNRATGHAAGPPGPWGLPSARSEAYGNAYAYVVDGFTVIELHGEI
                     DLVTAARAGPLLDAALTCPAPRVIVDLRPTAFFDCSALTLLCRSRRRALENDGRFALVC
                     ARPWHLRILRTAGLSTLLHPQATVEAVLGGGLLHPGA"
     gene            complement(3281..4309)
                     /locus_tag="A6A06_RS18305"
                     /old_locus_tag="A6A06_39390"
     CDS             complement(3281..4309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088616.1"
                     /locus_tag="A6A06_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39390"
                     /product="DNA-3-methyladenine glycosylase 2 family protein"
                     /protein_id="WP_199930975.1"
                     /transl_table=11
                     /translation="MTVTAAVSLVPAGLFSLASGIRFLECFTPAGYDHAADGILRLAFP
                     ADDSTSVVAAAVRQEAGTGGGTGTVRAEFTVHPAAPAPAEAATAEAADDEAVRAQLARI
                     LSLDVDGTGFPALAADPVVAGLMADYPGLRPVCFYSPYEAAAWAVIGNRIRVAQAAVFK
                     ARIARRHGQGVHIAGQTLYAFPTPAVLRTITHVPGLTDIKIQRLHALAEAALDGQLDAA
                     RLRALPSDYALAELRSLPGIGPFSAELVLIRGAGHPDVFPRHEPRVHRAIATAYGLDGP
                     AAADVSGLAEIADRWRPYRSWIATLLRTRAAEGTAMPVPHGSGPGRARWAAEPAITRAA
                     PR"
     gene            complement(4306..4677)
                     /locus_tag="A6A06_RS18310"
                     /old_locus_tag="A6A06_39395"
     CDS             complement(4306..4677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571467.1"
                     /locus_tag="A6A06_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39395"
                     /product="VOC family protein"
                     /protein_id="WP_073762382.1"
                     /transl_table=11
                     /translation="MSVTIDGPDFVALQVRDLDAAAAFCEQHLGLRRAAVSPPHAVVFD
                     TEPTPFAVRELLPGVDLADTARPGLGVLLWFRTPDAHKLHEQLTAAGVKILTPMEDSPF
                     GPKFSFEGPEGYVLTAHGG"
     gene            4757..5218
                     /locus_tag="A6A06_RS18315"
                     /old_locus_tag="A6A06_39400"
     CDS             4757..5218
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151172.1"
                     /locus_tag="A6A06_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39400"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_199930971.1"
                     /transl_table=11
                     /translation="MMENMPTEPPHPAKDVTHHVGYLLKRAQAALRGAMDQVLREHGLT
                     VPQYATLELLALHPGMSNADLARATFVTRQSGNVVLRGLQEAGLITRPATADHGRARPA
                     RLTEAGQTRLAAVQSAVYAVEQRMITAIPTRRMAALLTDLDHIATALEE"
     gene            5362..5556
                     /locus_tag="A6A06_RS18320"
                     /old_locus_tag="A6A06_39405"
     CDS             5362..5556
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS18320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_39405"
                     /product="hypothetical protein"
                     /protein_id="WP_199930976.1"
                     /transl_table=11
                     /translation="MGVADGGHGGGQEEDGNGEVLHAGGWSVGWAGDVGQAGAPVGEAE
                     GAMEVEGAAGTGFGVGARV"
     gene            complement(5827..5997)
                     /locus_tag="A6A06_RS41775"
     CDS             complement(5827..5997)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS41775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199930972.1"
                     /transl_table=11
                     /translation="MLSAPRGLLFWLILVVLLFLIAIAPAQTAHTLIDIVHGIGRFFTG
                     LKKFVETLSAS"
     gene            complement(6261..8096)
                     /locus_tag="A6A06_RS18325"
                     /old_locus_tag="A6A06_39410"
     CDS             complement(6261..8096)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330472.1"
                     /locus_tag="A6A06_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39410"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_079194110.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 7.3e-79,
                     bitscore: 255.4, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPAPRPARTPQAADADGDIPVTSPRWLPQALRELSPREMAVVAE
                     QIRAFLIENVCRNGGHLDVNLGVVELTLALHRIFDSPRDALVFDTGHQAYVHKLITGRA
                     ADFGRLRRRGGLSGYPSRSESVHDWVENSHASTSISYADGLSAAFAAKGETGRWAVAVI
                     GDGALTGGLAWEALNNLGAAGGRRAVVVLNDNGRSHAPTSGALATHLAALTDSSDSPDV
                     RETHNIFTSLGFTYLGPVDGHDLGAVEAALREARAADGPVLVHAITAQGKGHPPAEADD
                     ADCPHAAGAVDEATGAARDAPAPTWTDVFGGELAELGAGRADVVAVCAAMLRPTGLGAF
                     ADRFPERTFDVGMAEQHAVCSAAGMSMGGLHPVVAVYATFLSRAFDQLLMDAALHRLPV
                     TLVLDRAGITGPDGPSHHGMWDHTLFSMVPGLRLAAPRDAATLRALLAEALADQDGPTA
                     LRFPKGAVGVDVPAVGRLGQVDLLSAVGRDVLLVGVGAMAGPCLSARDDLAARGLEVTV
                     AAPRWALPLPEELVQLAARHRLAVTVEDSSRAGGVGSALAQACTDAVVSTPVHTLGLPR
                     TFLTHGSRSELLAATGLDAGGIATAVLLAWNARRR"
     misc_feature    complement(6525..6527)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8734..9882)
                     /locus_tag="A6A06_RS18330"
                     /old_locus_tag="A6A06_39415"
     CDS             complement(8734..9882)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980504.1"
                     /locus_tag="A6A06_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39415"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_073762394.1"
                     /transl_table=11
                     /translation="MDQLRTQGDPLADETVATMFERGEVSDFNTLMRFFTTAGHKLPEG
                     LPRSAASYLEATGMPPAWVDWDIMERARLFFMDNAAHINTGLSFTAMPTTYAVPRVAKL
                     LASTHSMDYPSRRMANTGQFVTYLMQTNAFEEGSKFIPAAQKVRLLHAAVRHHLTGSGR
                     WDSERDGMPLCQEDMIGGQICFSILVLDAMHRLGIHMSQEGAEAYYYAWRVVGSILGCD
                     MEAAPKNLTEARAYADLYLLRNLGPSEEGVRLNNQLMRMYEDVVPGTLFDPIVPATIRF
                     LVGDTIADWLQVPRSPWDTAAKAVPLILGLLEAVEDSSPLGEWALDKAGSLVSGFELAS
                     LTRGRVMQYAIPEELKSDYGLRSQQARNQRWVPPAPTSVGAN"
     gene            complement(10001..11074)
                     /locus_tag="A6A06_RS18335"
                     /old_locus_tag="A6A06_39420"
     CDS             complement(10001..11074)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980503.1"
                     /locus_tag="A6A06_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39420"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_073762384.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3e-38, bitscore:
                     122.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDATGFKQRIDAYLGRLADEEEAELLRLSGELAPLCAQLRSSLT
                     SGKRLRAAFLYWGWRASGQPDCDGVIKAAAAMELVHAAACTHDDIIDDSRLRHGLPTAH
                     AAFAAGGVGAWEAAAEQPHGHRQDRSAALAMMLGDLLMGYAGKVFATCGLPGAYVARTV
                     PLWSSLLRETVAGEFLEVLRTGGGTSGVAESLEVARYKTAKYTVERPLHMGATLGGASR
                     GVHAAFTGYGLPLGEAFQLRDDLLGTFGDPGRTGKSNLDDLRDGKPTALLALTRSLLSP
                     EDGRLLAKTLGGPRLDEAGAALVRELMEHSGARQRVEDMIEERIARARAALDSVALPAD
                     ARSVLGALAASAADRSL"
     gene            complement(11067..11414)
                     /locus_tag="A6A06_RS18340"
                     /old_locus_tag="A6A06_39425"
     CDS             complement(11067..11414)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A6A06_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A6A06_39425"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_199930973.1"
                     /transl_table=11
                     /translation="MPEQKEGTDSAGTDPAGTDPSGGHATAGAEHLALLAVGIADFALE
                     RLRDAADRGRHLLHRSDLRDLLADGLNDLRARGELASRRVTPDTGNHLEVMACRAAQRA
                     AAADASGPAHA"
     gene            complement(11673..13757)
                     /locus_tag="A6A06_RS40915"
                     /old_locus_tag="A6A06_39430"
     CDS             complement(11673..13757)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959829.1"
                     /locus_tag="A6A06_RS40915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39430"
                     /product="DUF4157 domain-containing protein"
                     /protein_id="WP_242440806.1"
                     /transl_table=11
                     /translation="MQQRDEAREAGTGGKRPAGRRAAPRAGGPHASLLALQAKAGNAAV
                     VQTLRQAGHTGAAPDRHVHGAGCGHEQAEKPPVQRSAVHDVLRGAGRPLDDSVRADMEM
                     RLGADFSDVRIHDDTSARASAAELGARAYTSGSHIVVGAGGGDRHTLAHELTHVIQQRR
                     GPVSGTDHGDGVSVSDPSDRFEREAEATAARVLSLPPGHAAPAGTAASAPGTGHSPAPG
                     TRQPSGPGVTAQRLTRGSRGSRRAGREDPGYALAEAQRTQIESLPALYVPAETFGRDGS
                     QPSVPRSAYAVPQPGDVEILQMRASPLPAVSHHAPGPRADWPMKYQSGQFVYEIQMVNR
                     PHRAGTTLIDPTRGFEVVKRKLKMRDSGHSAGRTYRFQERWAPNPAYWGPMPGPEAELA
                     AQAAGLGPDSRLMQADLPYFRNLPAPRDQPFVFSVANDRVDPHFGRSDGTQKDSRKDVS
                     AAHFDHKAARAGSGDTRLKAYTALSSPPQVGRGDAGRSPHRTMGNVQAHELMGDDGRKG
                     SSGTRLASHEWCHLVGDGDGGLDIPENLVIGTNAVNTEQLAMETALRPLVPHLRARGYS
                     IQLDVEVLVGKTPERRSGVPGGSWNLAKYISYRISLVPEGQVRSSLRREIHRQIMDGRR
                     GTITELEFTYLRRTVRAKLEAAIEEIDEAERAHQAQAAAFAYGGAGGQYPGSAGQPSYY
                     "
     misc_feature    13890..13906
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.29"
                     /tool="antismash"
     misc_feature    13989..14003
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.66"
                     /tool="antismash"
     misc_feature    complement(14094..14107)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            14237..16951
                     /locus_tag="A6A06_RS18350"
                     /old_locus_tag="A6A06_39435"
     CDS             14237..16951
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="A6A06_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39435"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_073762385.1"
                     /transl_table=11
                     /translation="MVTRRTIPVRFVARHAERREFDRSVTSAAAGRGGAMVVAGEAGIG
                     KSALIDAVVAELDGFEVLRAAGTEFEQDLPYATLHQLCAPVLDHRTGLPVVQRRALEAV
                     FGLGAQTSPDPLTFGLAVLGLLHEVARKRPVCCVVDDAQWVDDASRRALVFVARRVAAE
                     RIAVVFAARDVGSVSGLAGLPRLPLAGLGDEDARALLGAATQAGLDAEVVDRILAEARG
                     NPLALLEFAHRTEPFGVPGPRRCRASVVDTLEEQFVHRYERLPDATRLLVVLAAAEPVG
                     DLGLLRRAAELLGLDAAGFTLAENAGLLVLGPWLRFRHPLVRSAVYASATPGMRRRVHS
                     ALAEATDPETDLDRRAWHRAHAAVDADESVAAELERSADRARLRGGVAAAAAFMERAGQ
                     LTPAGDRQAGRLLVAAQLRLQAGAPDTARALVARAERRSMDEPERAGARLLRARIDYQL
                     SHSPQATAALVDAIAESAPDQARDTYLEAFASFMYNDNKPGGLKDLGVRIRERTPRRES
                     ALPADLLLDALLDQTMLPVGQAVPAMRDAVAAYRTAPSASEPWPMNLLCQVVIDLRDDE
                     AMDEITDRQVDVARSQGALALLPQALRYQAIARVAAGRFDEAAAALGEARAVDEAAGTA
                     PLLGPELILTGFRGDLDRYRELRGSMGREGRPFETAGEHYARAVLNNGLGDYEAALDAA
                     LAAQRRHRAGSYAIWSVYPELVEAAVRAGRGEEAVAALEHLEALARAHPLPWIVAEWLQ
                     AKALLGRGADCDTLYRQAIGHFARTRVRVLHARARLTYGEWLRRENRRAEARDELRAAY
                     DMLSRIGARAFAERAARELRATGEQPRRHGENPLGRLTAQERLIAGKVAAGATSKEVGV
                     MLFLSPRTIDTHLRNVYRKLGISSRRQLREMSL"
     misc_feature    15044..15046
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16974..18221)
                     /locus_tag="A6A06_RS18355"
                     /old_locus_tag="A6A06_39440"
     CDS             complement(16974..18221)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641037.1"
                     /locus_tag="A6A06_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39440"
                     /product="hypothetical protein"
                     /protein_id="WP_073762386.1"
                     /transl_table=11
                     /translation="MTTPDCSACGTRAEPGQSFCDACGAVLRWEPAGGRTGPPAAPSTA
                     PGRGVSAAAPGHTGHRDSTGTPGAPPPSPGAPRPTPAAPRPTPGPPDEEDTDPGIPLST
                     TYNSAPSASPSADRARSLVVPVTDPEAATPAAPAPAVTPVLPGRPDTERPLVRGPASRG
                     PVHGAPCPWCATPNPADRHFCCRCAMPFAEHGAAPAPVPRPWWRRLLGPGRQETPWAGD
                     RPRLRRVFDRIGTWITAAVAVTLLILGVLYVPDGIQATGDHFAKRAPVEPDGIRASRSY
                     PGHGPKLAFDKLNNTWWGPGVSQSGQGEWIEVRFARPVRLLDLVITPGVSVRADQLDRS
                     ALPHRVRATITGKDGRTETRDLTLDPGAGEQRRAFRVGEATAVRFTIESAHAASAEKQV
                     AIAEIEFFGRSSGGPG"
     gene            complement(18218..18727)
                     /locus_tag="A6A06_RS18360"
                     /old_locus_tag="A6A06_39445"
     CDS             complement(18218..18727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435797.1"
                     /locus_tag="A6A06_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39445"
                     /product="phage tail protein"
                     /protein_id="WP_079194113.1"
                     /transl_table=11
                     /translation="MLPAVFADDDLAQRFVAGLDDVLAPILNVLDCLDAYFDPALTPAD
                     FARWLGTWVGAETDGTEPEPRLRAAVAAAVGLHRVRGTRRGLSEAVRLAFGTAPEITES
                     GGAAWSARPRGPFPGSARPHLHVTLRLPEPTRADTYRLDALVAAARPAHMPYTVTITAA
                     ERTSET"
     gene            complement(18804..20762)
                     /locus_tag="A6A06_RS18365"
                     /old_locus_tag="A6A06_39450"
     CDS             complement(18804..20762)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326691.1"
                     /locus_tag="A6A06_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_39450"
                     /product="putative baseplate assembly protein"
                     /protein_id="WP_073762396.1"
                     /transl_table=11
                     /translation="MSLPSPNLDDRRFQQFVDDAKRYIQQRAPEWTDHNVSDPGITLVE
                     TVAHMADQIVYRLNRVPEKNHLAFLDLVGVTLFPPSAARTDVTFWLSAPQEEAVAVPVG
                     TEVATLRTEQEEAVVFATEHALAVVPCELSRLVVQHRGEPVADHTTALAEGTHVRCFAE
                     TPGPGDCMLIGLTAAVPRCAVALELDSRVDGVGVDPRQPPLVWEAWTEDGWQPCETDRD
                     GTGGLNRAGDIVLHVPGGHVLSRTGGHEAGWLRCRVTEPLPGQPFYTTSPTVRAAAACT
                     IGGTTGVVHAATVHDEALGESSGLPGQRRRLAHAPVVGDDPPLLLQTAGPDGWQDWQVV
                     PHFAASRPDDHHITLDATTGDIAFGPAVREADGTLRQYGMVAPKGAAVRARRYRTGGGR
                     AGNVTRGAIRVLRTSIPYVSEVANRETARGGVDGETVAEAKVRAPITLRAQERAVTLRD
                     YEELARRAAPETARITCLEGVPDEHGSYAVRVLVVPQAVPDPGGRLRFEQLVPGDRLLD
                     RITRHLDERRLIGTRLAVGPPYYQGVTVVATVHAFRGVDTDRVRRRAHDALYRHLDPLT
                     GGAEGHGWPFGRPVQAGEVFAILQRVPGVELVDEVVLHPADPLTGRRGDPTDRIDLQPP
                     SLVFSFDHRVRVVGDST"
ORIGIN
        1 acacggcccc ggcccggctc ccgggtttag cgcctacgtc accaacccag gccctcgccc
       61 cataggatgg cccgactgcg tcacacagcg tacgcggcag aagcccactc gaagggctga
      121 ctgcgcacgt taccgacgtc tgcagcgatc cctccctggg gagaattggg ggagtatggc
      181 cgccgttggg gagcggctgg ggagaatcgg ccgcataacg cggcatggcc ctgaaagacg
      241 cagaaagacc catcggtgca ggtcagagac ccgcgacacc gcacactcgc aggtcagccc
      301 gatgcggtag acgacttcat gacgtacgta ccgaaatcgt caccctcgac gatccccgga
      361 agcgaccctc cctcacgcaa gggcgtgacg tagcgggtcg cggtgacttc ggacaacatg
      421 cggatcaggc tacttcctgg gggtcgtcgc aggtcagcgg ccgatggtcg attcagcgcg
      481 ccggtaacgg ggccactata acgatgcgct tgcatcagtt ccaggtgtgc cgcgccccgg
      541 acgcgaagat gcgccgtgcc cgcatgcgga aatgtgccgt gccccggacg cggaggggag
      601 cccggcgggc cccgaaaacc tgttggcgga ccgctgcggc cactgctagt tttcgggcgg
      661 ccgtgcgaga gaacgaggag gtggtacccg tgaacgcagt atcgacatgg gtgctcccct
      721 caggggtcac ggtcgggcgg taggtcgtcc gggagcgccg ttcacgagcc ctcccgaaag
      781 gcacgaccat gcgcttcact tccggacaac gcctcgacaa cggcgtcctc gaacgcgaat
      841 tcaccctcgg cgagatcccc ggcaccctgt ggatgcccga atccgccgca ccggccccgc
      901 tgatcctgat ggcccacaac aacggcctgc ccaagaagga agcccggctg gtggcacggg
      961 cccggcactt cgcggcgtac ggctacgcgg tggccgccat cgacgccccc gggtgcggcg
     1021 accggccccg ttccgccgct gacgaacagg cccgcgccga catccgccgg gcgatgcgga
     1081 ccggcgagcc gaccgacgag atccttgagt cgttcgtcgg cccgctggtc gaaaaggcgg
     1141 tcccggaatg gcggaccacc ttggacgccc tcctcgcgct gcccgagatc ggcggcccgg
     1201 tcgggtattc ggggtggacc gccctcggca tccggctggc ggtggccgaa ccccgcatcg
     1261 cggccgccgg tttcttcgcc ggggggtacg tgccccgcgc ccagcgcgag gaggcccggc
     1321 aggtcaccgt tccactgctg ctcctgttgc agtgggacga cgaagggaac ccccggcagc
     1381 gggccctgga cctgttcgac gccttcggcg ccaaggagaa gacgctgcac gccaatatgg
     1441 gcgggcacac cggcacaccg tggttcgagg tggaggacgg gggccggttc ttcggccggc
     1501 acctgaagtg aggccgggcc gtcggggtgg ccggcagctg cacgacccgg tggtcgacag
     1561 ctgcacgacc gccccggccg cggctgtcag gccgacggcc gcggtgggcc actgcgtcac
     1621 tgctgttgtt gatcgacttc gccggaacgg aacggccgtt gtagcacttg cccggctgcg
     1681 cagcgatgtc accggaccgg cccttgaagt tgtactccga ccagaggcag acgtgattct
     1741 gtgcgcacga accgctcgcc gcctgagcag gcgcggacat gatcgtcgca ccgagacagc
     1801 ccgccgccgc cccgacggcc ggttcggacc gtcccgcccg tgcggcctca gccgggcaga
     1861 cattgccaag tggtcctggc atagggggtg ttccggcgtc ggccaggttg gggatcagat
     1921 ggagcgggca tctgcgtcag gtcggaccgg ccgctcaccg cgagcggccc cgcaggctcg
     1981 cggtacaggc ctgcggcggt cccggggagg gaagtggtga cgatgcgccc gtaccggcgt
     2041 gggcctgccc gaaggcgtag gacccgagtg gagtacaccc tgccggacga tgcggaatca
     2101 gcccgctggg cacggcggct gaccacggcg ttcctcaccg accgccgggc acccgccgga
     2161 gcccgcgagc aactggacga cgcccggctg atcgtctcgg agctggtcgc caacgccgcc
     2221 gaacacggcc acagcgcctg ccgactgcgg ctccgcgtcg accagggcga actgacggtg
     2281 gaagtccagg acgacagccc gctcccgccc cgcaccggga agctgtcgct gtgggcggag
     2341 agcgggcggg gcctggcgat ggtgcggctg ctggcgagcc gcttcgccgt caccggcgac
     2401 cgtgacggcg gcaagaccgt ccgtgcggtg ctggccgttt gctgaacggg gcggctctgg
     2461 tcgtctgccg accaggcggt cccggccgtc tgccgaccgt ccgcgcgtgc gtcgctcgtt
     2521 cggggcaacg gcgagtgtcc ggccgtttcc ggtaggcgac ttctctaccc tgctgtccgt
     2581 caccccatct cctggtgatg ctgtctgctg agcgcacgat cccgccatcg ccggttcggg
     2641 acgtgccgga ccaggaccgg tgatgaacag agcaacaggc cacgctgccg gaccgccggg
     2701 cccgtggggc ctgccgtcgg cccggtccga ggcgtacggc aacgcgtacg cctacgtcgt
     2761 cgacggattc accgtgatcg agctgcacgg cgagatcgac ctcgtcaccg ccgctcgcgc
     2821 cggcccgctg ctggacgccg cgctcacctg cccggccccc cgggtgatcg tggacctgcg
     2881 gccgacggcc ttcttcgact gctccgccct gacgctgctc tgccgaagcc gccgccgggc
     2941 cctggaaaac gacggccgct tcgccctggt ctgcgcacgc ccctggcatc tgcggatcct
     3001 gcgcacggcc gggctgagta cgctcctgca cccccaggcc acggtggagg ccgtcctcgg
     3061 cggcggcttg ctccacccgg gagcctgacg ggtacgagcc tgacgggtac gagcctgacg
     3121 ggtacgagcc tgacgggtac gagttggatg ctcggccgga gccaggtggc ccgccgggcg
     3181 gggggccagg ctcggcagcg gacggatttc ccgatcgccc gaggcacgtc agccgaccat
     3241 cccggttccg ctgcaccaag ccaccatcca ggcggcgaca tcaccgaggc gcagcgcgtg
     3301 tgatggctgg ttcggcggcc catcgagcac gtcccggacc cgaaccgtgc gggaccggca
     3361 tcgccgtccc ctccgcggcg cgggtgcgga gcagggtggc gatccagctg cgatagggcc
     3421 tccagcggtc agcgatctcg gccagtccgg aaacgtccgc ggcggccggg ccgtcgagcc
     3481 cgtacgcggt ggcgatggcc cggtggacgc gtggttcgtg gcgggggaag acgtcggggt
     3541 gtcctgctcc ccggatcagg acgagttcgg cggagaaggg gccgatgccg ggcagggacc
     3601 gcagttcggc gagggcgtag tcggagggca gggcgcgcag gcgggctgcg tcgagttgcc
     3661 cgtcgagggc ggcttcggcc agcgcgtgca gtcgctggat cttgatgtcg gtcaggccgg
     3721 gcacgtgggt gatggtgcgc aggacggcgg gggtggggaa cgcgtacagg gtctggcctg
     3781 cgatgtggac gccctgtccg tgacggcggg cgatacgggc cttgaagacc gccgcctggg
     3841 ccacgcggat gcggttgccg atgacggccc aggcggccgc ttcgtagggc gagtagaaac
     3901 acaccggacg cagccccggg tagtccgcca tgaggccggc caccacggga tccgcggcga
     3961 gggccggaaa tccggtgccg tcgacgtcga gggagaggat gcgggcgagc tgagcccgca
     4021 cggcctcgtc gtcagcagct tcggcggtcg ccgcctccgc cggggcgggg gcggcggggt
     4081 gcacggtgaa ttcggcccgc accgtgccgg tgccgccgcc tgttcccgcc tcctgccgga
     4141 cggcggccgc gaccacggag gtcgagtcgt cggcggggaa ggccaggcgg aggattccgt
     4201 cggccgcgtg gtcgtaaccg gcgggggtga agcactccag gaaccggatg ccggaggcga
     4261 gggagaagag ccccgccgga acgagggaga cggcggcggt cacggtcagc ctccgtgcgc
     4321 ggtgagcacg tagccctccg ggccctcgaa agagaacttc ggcccgaagg ggctgtcttc
     4381 catgggggtg aggatcttga ccccggctgc ggtgagctgc tcgtggagct tgtgggcgtc
     4441 gggagtccgg aaccagagca gcactccgag gccgggccgt gcggtgtcgg cgaggtcgac
     4501 gcccgggagg agttcgcgga cggcgaacgg tgtcggctcg gtgtcgaaca cgaccgcgtg
     4561 cggcggcgaa accgcggctc ggcgcaggcc caggtgctgc tcgcagaagg cggccgcggc
     4621 gtccaggtcg cggacttgga gcgccacgaa gtcggggccg tcgatggtga cagacatggg
     4681 ttttcctcgc ttctgatgtc agtgttttga catcagggag actaagacgc cagggcactc
     4741 atgtcaaaat gctgacatga tggagaacat gccgaccgag ccgccccacc ccgcgaagga
     4801 cgtcacccac cacgtgggat acctgctgaa acgcgcccag gccgcgctgc gcggcgccat
     4861 ggaccaggtc ttgcgcgagc acgggctgac cgtgccgcag tacgccaccc tcgaactcct
     4921 ggccctgcac cccggcatgt ccaacgccga cctcgcccgc gcgaccttcg tcacccggca
     4981 gtccgggaac gtcgtactgc ggggcctcca ggaagcagga ctgatcaccc gccccgccac
     5041 cgccgaccac ggccgcgccc ggcccgcccg cctcaccgag gcgggccaga cgcgcctggc
     5101 cgcggtccag tccgccgtct acgccgtcga acagcgcatg atcaccgcga tcccgacccg
     5161 acgcatggcc gcgctcctca ccgacctcga ccacatcgcg acagccctgg aggaatgacc
     5221 cgccagcctg tttccgaccg ctgccggacg cgatcgacac cggaaggcgc gggcccgtcc
     5281 ggtgtcgggg cggatgagca ggagggtgtg ggtgcggggg tgggggtggg ggtgagtgcg
     5341 ggggtggggg tgagtgcggg ggtgggtgtt gctgacggcg ggcacggagg cggccaggag
     5401 gaggacggca acggcgaagt gctgcacgcg ggcggctggt cggtcggctg ggccggtgac
     5461 gtggggcagg cgggagcacc ggtcggagag gcggaggggg cgatggaggt ggagggggcc
     5521 gctgggacgg gcttcggggt gggggcccgg gtgtgagtgg cggagggcgg ggccggtgcg
     5581 gaggtcacgg cacggggcgc tcccggagtg acggagaccg tcacggtcgc ggggccgctg
     5641 ggcggtggcg ccgcggaccc gctcgtcaga ggcgcgccgg tgacgggcag cgggacgacg
     5701 tgtacgtccg ctttcgtcga cggcacggcc gcgcaggcga cggctgccag gacgatgcag
     5761 cccgtgagga tgaacagcag ggttcgcacg ggttcggctc cttcgtcggc gagggacagc
     5821 aggcggtcag gaggcgctga gggtctcgac gaacttcttc aggccggtga agaacctgcc
     5881 gatgccgtga acgatgtcga tgagggtgtg ggcggtctgg gccggggcga tggcgatgag
     5941 gaagagcagg acgacgagga tgagccagaa gagcaggccg cggggcgcgc tcagcacggc
     6001 ggtgcctcct tccggcgtcg tgagacgcgg ctgggccggt gcctgggtac acggttgggc
     6061 cggtgcctgg gtacgcggct gggccggtgc ctgggtacac ggctgacggt ggcgccgcca
     6121 cccggcgacg gcgagggcca tggcgagcgc gtggttacag gccgcccttg cggcaggtcc
     6181 tccagggcgc ggccgacggg gagttggttg atctgcacgg tccgttcgcg gtcatcacag
     6241 cctccgggtg cggtgcgaga tcaccggcgg cgggcgttcc aggccaggag gacggcggtg
     6301 gcgatgcccc cggcgtccag gcccgtcgcg gccagcagtt cgctgcggga gccgtgggtc
     6361 aggaaggtgc gcggcagccc cagggtgtgt acgggggtgg agacgacggc gtcggtgcag
     6421 gcttgggcca gggcgctgcc gaccccgccc gcacgggagc tgtcctcgac ggtgaccgcc
     6481 aggcggtgac gggcggccag ctgtaccagt tcttcgggca gcggtaacgc ccagcgcggg
     6541 gcggcgacgg tgacctccag tccgcgcgcg gccaggtcgt cgcgagcgct caggcaaggg
     6601 ccggccatcg cgcccacccc caccagcagc acatcgcgcc ccacggcgga cagaaggtcc
     6661 acctggccca ggcggcccac cgccggtacg tccacgccca ccgcgccttt gggaaaccgc
     6721 agggccgtgg ggccgtcctg gtcggccagc gcctcggcga gcagggcccg caaggtggcc
     6781 gcgtccctgg gagcggccag gcgcagtccg ggcaccatgg agaacagcgt gtggtcccac
     6841 atgccgtggt gggaagggcc gtccgggccg gtgatgccgg cccggtccag gaccagggtg
     6901 accgggaggc ggtgcagcgc ggcgtccatc agcagctggt cgaaggcgcg ggagaggaac
     6961 gtggcgtaca cggcgaccac tgggtgcagt ccccccatcg acattcccgc ggcggagcac
     7021 accgcgtgct gctcggccat gcccacgtcg aaggtgcgct caggaaagcg gtcggcgaac
     7081 gcgcccagcc cggtcgggcg cagcatcgcc gcgcacaccg ccaccacatc ggcacggccc
     7141 gcgcccagct cggccagctc accgccgaac acatcggtcc aggtcggtgc cggggcatcg
     7201 cgggctgctc cggtggcctc gtcgacggcg cccgccgcgt gcgggcagtc cgcgtcgtcg
     7261 gcctctgccg gagggtggcc cttgccttgg gccgtgatgg cgtgcaccag taccggcccg
     7321 tcggccgcgc gcgcctcccg caaggcggcc tccaccgcgc cgaggtcgtg tccgtccacc
     7381 ggtccgaggt aggtgaaccc cagggaggtg aagatgttgt gcgtctcgcg cacgtcgggt
     7441 gagtcggagg aatccgtcag ggcagcgagg tgggtggcca gggctccgct ggtcggggcg
     7501 tgggagcggc cgttgtcgtt gagcaccacc acggcccgcc gtcccccggc cgcgccgagg
     7561 ttgttcagcg cttcccaggc cagcccgccg gtcagggcgc cgtcgccgat gaccgcgacc
     7621 gcccaccggc cggtttcccc cttcgcggcg aacgccgcac tcaggccgtc ggcgtaggaa
     7681 atgctggtgg acgcatgcga gttctccacc cagtcgtgca ccgattcact gcggctgggg
     7741 tagccggaga gcccgccgcg ccgacgcaac cggccgaaat ccgcagcccg gcccgtgatc
     7801 agtttgtgta cgtaggcctg gtgcccggtg tcgaagacca gagcgtcccg gggtgagtcg
     7861 aagatccggt gcagggccag cgtcagctcc accacaccca ggttgacgtc caggtgaccg
     7921 ccgttgcggc atacgttctc gatcaggaag gcgcggatct gctcggcgac cacggccatc
     7981 tcacgcggcg acagctcccg cagtgcctgc ggcagccagc gcggcgatgt cacgggtatg
     8041 tcgccgtcgg catcggcggc ctgcggtgtc cgggccggtc tcggagctgg acgcatcgat
     8101 ttccctcggg ggtgggggat catgaacggg ggcgtggagg acggcgggca ccgccgcctg
     8161 acatgcctgc acccaggggg aaaccacccg gcatcgaaga ggcggttccc ccctggtacc
     8221 agcccggccc cacgttgtgg catcgcgcac cgcggcgctg ccgagctgcc ctttgagccc
     8281 accgcagacc gcggtccctg acaacccccg ttccggcagc gcacggagta acaccaccgg
     8341 gtgcttcttc ggcgcacgcg ccgcacgggc acagctcggc tgccgccgcc ggctcgcccg
     8401 gcgcaccacc ccgtcacacc ggccggtcaa cggctcttct gccccggtgg cgcctgcaac
     8461 cggccagctc acggtgcgtc cggtacgggc cgtacgcagc ggccgacccg ccctcgcagc
     8521 caccacctgc gccacccggc cacagcagtc agccgccgcc ttcgccgaag accgaccgtc
     8581 cgctgcatcg cgcgcccctg acgaccgtca acaacccgcg agcctccgtg cgcccttggc
     8641 agcggccatg gccctgctag cgtcctgagt ggcgtgcgga gcccggcggc ttcggcgccc
     8701 cggccacatc cccctgaagg aactgcgccc ttctcagttc gcccccaccg acgtgggagc
     8761 gggtggtacc cagcgctggt tgcgtgcttg ctgcgaccgc aggccgtagt cggatttgag
     8821 ttcctcgggg atggcgtact gcatcacccg gccgcgggtg agagaggcga gttcgaagcc
     8881 ggagaccagg ctgcctgcct tgtccagtgc ccactccccc agcgggctgc tgtcctcgac
     8941 agcctccagc aggccgagga tcaggggcac ggccttggcc gccgtgtccc acgggctgcg
     9001 ggggacctgc agccagtcgg cgatggtgtc gcccacgagg aagcggatcg tggccgggac
     9061 gatcgggtcg aacagcgtgc cggggacgac gtcctcgtac atccgcatca gctggttgtt
     9121 cagccgtacg ccctcctccg agggccccag gttgcgcagg aggtagagat cggcgtacgc
     9181 gcgggcctcg gtgaggttct tcggcgctgc ctccatgtcg cagcccagga tggagccgac
     9241 gacacgccag gcgtagtagt acgcctccgc gccctcctgg ctcatgtgga tgccgaggcg
     9301 gtgcatcgcg tccagtacga ggatcgagaa gcagatctgc ccgccgatca tgtcttcctg
     9361 gcagagcggc atgccgtccc gctcgctgtc ccagcgcccg gacccggtca ggtgatggcg
     9421 caccgcggca tgcagcaggc gcaccttctg cgcggccggg atgaacttgc tgccctcctc
     9481 gaaggcgttg gtctgcatca ggtacgtgac gaactgcccg gtgttcgcca tccggcgcga
     9541 cgggtagtcc atggagtgcg tggaggccag cagcttggcc acgcgcggta cggcgtacgt
     9601 ggtcggcatg gcggtgaagg acaggccggt gttgatgtgc gcggcgttgt ccatgaagaa
     9661 cagccgtgcg cgctccatga tgtcccagtc cacccatgcc gggggcatgc cggtcgcttc
     9721 caggtaggac gccgccgacc gcggcaggcc ctccggcagc ttgtgtccgg cggtggtgaa
     9781 gaagcgcatg agggtgttga agtccgatac ctctccgcgt tcgaacatgg tcgccacggt
     9841 ctcgtcggcg agcgggtcgc cttgggtacg cagctggtcc agcgtcgcgt cggtgtaccg
     9901 cgcggtggtc tcagcggtgt cagtggcctc agcggttccg gtggtctcag cggttccggt
     9961 ggtctcggtg gtcacgggtt cctcgtctct ctcgtcgccc tcacagggac cggtcggccg
    10021 ccgaggccgc cagcgcaccg agcaccgagc gcgcgtccgc gggcagcgcc acggagtcca
    10081 gcgccgcgcg ggcccgcgcg atccgttcct cgatcatgtc ctcgacgcgc tgccgcgcac
    10141 cgctgtgctc catcagctcc cgtacgagcg ccgcaccggc ctcgtccagg cgcgggccgc
    10201 ccaaggtctt ggccagcagc cgcccgtcct ccggagagag cagcgagcgg gtcagcgcga
    10261 gcagggcggt gggctttccg tcccgcaggt cgtccaggtt cgatttcccc gtccggcccg
    10321 ggtcgccgaa ggtgcccagc aggtcgtcgc ggagctggaa ggcttcgccg agcggcagcc
    10381 cgtatccggt gaaggctgcg tgtacgcccc gggaggcgcc gccgagcgtg gcccccatgt
    10441 gcaacggccg ctccacggtg tacttggccg tcttgtaccg ggcgacctcc agggattcgg
    10501 cgacgccgga cgtgccgcct ccggtacgca ggacttccag gaactcccct gcgacggtct
    10561 cgcgcagcag cgaggaccac aggggcaccg tccgcgccac gtaggcgccg ggcaggccgc
    10621 aggtcgcgaa gaccttgccc gcgtacccca tcagcaggtc gcccagcatc atcgcgagcg
    10681 cggcggaacg gtcctggcgg tgtccgtggg gctgttcggc cgcggcctcc caggcaccga
    10741 caccgcctgc ggcgaaggcg gcatgggcgg tcggcaggcc gtgccgcagc cggctgtcgt
    10801 cgatgatgtc gtcgtgggtg cacgcggccg cgtgcaccag ctccatggcg gccgcggcct
    10861 tgatcacgcc gtcgcagtcc ggctgcccgg aggcccgcca gccccagtag aggaaggcgg
    10921 cgcgcagccg cttcccgctc gtcagcgagc tgcgcagctg ggcgcagagc ggggcgagtt
    10981 cgccggagag gcgcagcagc tcggcttcct cctcgtcggc gagccggccc aggtacgcgt
    11041 cgatgcgctg cttgaatccc gtcgcgtcat gcatgagccg gtccggacgc gtcggccgcc
    11101 gcggcccgct gcgccgcgcg gcaggccatc acttcgaggt ggttgccggt gtccggcgtg
    11161 acacggcggg aggccagttc gccacgggcg cgcaggtcgt tcagcccgtc ggcgagaagg
    11221 tcccgcaggt cggagcggtg cagcaggtgc cggccccggt ccgcggcgtc ccgcagccgt
    11281 tcgagtgcga agtcggcgat gccgacggcg agtagggcca ggtgctcggc tccggcggtg
    11341 gcgtgccccc cggacggatc ggtccctgcg gggtcggtac ctgcggaatc ggttccctct
    11401 ttctgctccg gcatgtccgg tactcccttg ctcccgttcc gatgcgatcg tccgaccgcc
    11461 cgggagctac cagtgaaccg atccgcacgg acgcaagccg ctgttccggc tccccgcccc
    11521 ccgccggtgg accacaattc ctacgatgga gtgacgatca ccccatcacg cggacagcgc
    11581 cggtcccgat cccgtacggc ggcggctccg caccgtgtcc cccggagggg aacagcaccg
    11641 ggcgcgggcc cccggaccag gcttcagcgg catcagtagt aggagggctg ccccgcggag
    11701 cccgggtact ggccgcccgc cccgccgtag gcgaacgccg cggcctgcgc ctggtgcgcc
    11761 cgctccgcct cgtcgatctc ctcgatggcc gcctccagct tcgcgcgcac cgtacgccgc
    11821 aggtaggtga actccagctc cgtgatggtg ccgcgccgcc cgtccatgat ctgccggtgg
    11881 atctcccgcc gcaggctcga acgcacctgc ccctccggga cgagcgagat ccggtaactg
    11941 atgtacttgg caaggttcca gctgccgccg gggacaccgg agcgccgttc gggcgtcttg
    12001 ccgaccagga cctcgacgtc cagctggatc gagtagcccc gggcgcgcag gtgcggcacc
    12061 agcgggcgca gcgccgtctc catggcgagc tgctcggtgt tgaccgcgtt ggtgccgatc
    12121 accaggttct cggggatgtc caggccgccg tcgccgtcgc cgaccaggtg acaccactcg
    12181 tgcgaggcca ggcgcgtgcc ggacgagccc ttgcgcccgt cgtcgcccat gagttcgtgt
    12241 gcctggacgt tgcccatggt gcggtgcggg ctgcggcccg cgtcgccgcg gcccacctgg
    12301 ggaggcgacg agagtgccgt gtacgccttc agccgggtgt cgccggagcc cgcgcgcgcg
    12361 gccttgtggt cgaagtgggc cgcgctgacg tccttgcggc tgtccttctg ggtgccgtcc
    12421 gagcgcccga agtgcgggtc gacgcggtcg ttggcgacgg agaacacgaa gggctggtcc
    12481 cgcggggccg gcaggttccg gaagtacggc aggtcggctt gcatgaggcg gctgtcgggg
    12541 cccagccccg cggcctgcgc ggcgagttcg gcctccggtc ccggcatggg gccccagtac
    12601 gcggggttgg gcgcccagcg ctcctggaac cggtaggtgc gccccgccga gtggccgctg
    12661 tcgcgcatct tcagcttgcg cttgacgacc tcgaagccgc gggtggggtc gatgagggtc
    12721 gttccggccc ggtgcggccg gttgaccatc tggatctcgt agacgaactg tcccgactgg
    12781 tacttcatcg gccagtcggc ccgcggtccg ggggcgtggt gggagacggc ggggagcggg
    12841 gaagcccgca tctggaggat ctccacgtcg cccggctgcg ggaccgcgta cgccgacctg
    12901 ggcacggacg gctggctgcc gtcgcggccg aacgtctccg ccggcacgta cagggcgggc
    12961 agggattcga tctgggtccg ctgcgcctcg gccagcgcgt agccggggtc ttcccggccc
    13021 gcgcgtcgcg agccgcggga gccgcgcgtc aggcgctgcg cggtgacgcc cggcccggac
    13081 ggctgcctgg tacccggtgc gggcgagtgc ccggtgcccg gcgcggacgc tgccgtcccg
    13141 gcgggtgcgg cgtgccccgg aggcaggctc agtacgcggg cggcggtggc ctcggcctcc
    13201 cgctcgaacc ggtcggacgg gtcggagacg ctcaccccgt cgccgtggtc ggtaccggag
    13261 accgggcccc ggcgctgctg gatgacgtgg gtgagctcgt gcgcgagggt gtgccggtcg
    13321 cctccgcccg cgccgacgac gatgtggctg cccgaggtgt aggcgcgggc gccgagttcc
    13381 gcggcggacg ccctggcgga cgtgtcgtcg tggatgcgga cgtcggagaa gtcggcgccg
    13441 agccgcatct ccatgtcggc gcggaccgag tcgtccagcg gccggcccgc gccgcgcagc
    13501 acgtcgtgca cggcggaacg ctgcaccggc ggcttctccg cctgctcgtg accgcacccc
    13561 gcgccgtgca cgtgccgatc cggtgccgcg ccggtgtggc ccgcctgccg cagtgtctgc
    13621 accacggcgg cgttaccggc cttcgcctgg agagcgagga gggacgcgtg cggtccgccg
    13681 gcccggggcg cggcgcggcg gcccgcgggc cgcttcccgc cggtgccggc ctcccgggcc
    13741 tcgtcacgtt gctgcacggg atctcctccg ggatgtcggg acgtctccat cgccccacgc
    13801 cgggcggtat ctctcttcat aagcgggaca ccgccgtgtc ggccaggtac gcgagggcag
    13861 tgtcgtccgg tcgaacgggc accatcgtcc gccggaaaac cgggcacact cccgggccaa
    13921 gcccatgatc gtgttccgcc gccgcggcgg gctgcgacca actcggccct gtatgcctcc
    13981 tgttcggtgg gccgaccggc cgtgcccctc agggccgcac tcccgtcttt tgtgccgtcc
    14041 gggggcgaac ctgtcgggcg ggtccggcat ctagcaggtg tgacatctgt caggaaacca
    14101 acggttgcgg ggctgccccg gtgtaccccg ccgtcggcgt ggatgccccg ggccgccggc
    14161 ccgctcgtgc cgtggcgcgg aacggacggc tccggcaccg gctccctggc atgcagatcg
    14221 tgggagacct caggcgatgg tgactcggag gacgattccg gtgcggttcg tggcccgaca
    14281 cgcagaacgg cgtgagttcg atcgatcagt gacctcggcg gccgccgggc ggggcggggc
    14341 catggtggtc gccggtgagg cggggatcgg caagtcggcg ctcatcgacg ccgtggtggc
    14401 ggagctggac gggttcgagg tgctgcgggc cgccggtacg gagttcgaac aagatcttcc
    14461 ctatgcgacc ctgcaccagc tgtgcgctcc ggtgctcgat caccgtacgg gacttcccgt
    14521 ggtgcaacgc agggcgctgg aggcggtgtt cggcctcggt gcgcagacct cgcccgaccc
    14581 gttgacgttc ggcctcgccg tcctggggct gctgcacgag gtggcgcgga agagaccggt
    14641 ctgctgcgtg gtggacgacg cccagtgggt cgacgacgcc tcgcggcgcg cgctggtctt
    14701 cgtggcgcgg cgggtggcgg ccgagcggat cgcggtggtg ttcgccgcgc gcgatgtcgg
    14761 ctcggtgtcc ggactcgccg gtcttccgcg tctgcccctc gcggggctgg gcgacgagga
    14821 cgcccgcgcg ctgctggggg cggcgacgca ggccgggctg gatgccgagg tcgtcgaccg
    14881 gatactggcc gaggcgcgcg gcaatccgct ggcgctgctg gagttcgccc accgtaccga
    14941 gccgttcggg gtgcccggcc cgcggcgctg ccgggccagc gtggtggaca cgctggagga
    15001 gcagttcgtc caccgctacg agcggctgcc ggacgcgacg cggttactgg tggtgctcgc
    15061 cgcggcggag ccggtcggcg atctcggcct gctgcgccgt gcggcggagc tcctcggtct
    15121 ggacgccgcg gggttcactc tcgcggagaa cgccggactt ctggtcctgg ggccgtggct
    15181 gcgcttccgg catccgctgg tgcgttccgc ggtctacgcg tcggccaccc cgggtatgcg
    15241 ccgtcgcgtg cacagcgctc tcgcggaggc gaccgatccg gagaccgacc tcgaccggcg
    15301 ggcgtggcac cgggcccacg cggccgtcga cgccgacgag agcgtcgccg cggagctgga
    15361 gcggtccgcc gaccgggccc gcctgcgcgg cggggtcgcc gcggcggccg cgttcatgga
    15421 gcgggcgggg cagctgaccc cggccggtga ccggcaggcc ggacggctgc tcgtcgcggc
    15481 ccagttgcgg ctccaggccg gggcgcccga cacggcccgt gcgctcgtcg cccgagcgga
    15541 gcgccgttcg atggacgagc cggaacgtgc cggggcgcgc ctgctgaggg cacgcatcga
    15601 ctatcagctc tcgcacagtc cgcaggccac cgccgcactc gtcgacgcca tcgcggagtc
    15661 ggctcccgac caggcgaggg atacgtacct ggaggcgttc gcctcgttca tgtacaacga
    15721 caacaagccg ggcggcctca aggatctcgg tgtccggata cgcgagcgga cgccgcggcg
    15781 ggagtccgcc cttccggccg atctgctgct cgacgctctg ctggatcaga ccatgctgcc
    15841 cgtcgggcag gcggtgcccg cgatgcgcga cgcggtggcg gcataccgta cggcgccctc
    15901 cgcgtcggag ccgtggccga tgaacctgct ctgccaggtc gtcatcgatc tgcgggacga
    15961 cgaggcgatg gacgagatca cggaccgcca ggtggacgtg gcacgcagcc agggggccct
    16021 cgccctgctg ccgcaggcgc tgcgctacca ggccatcgcc agagtcgcgg ccggccggtt
    16081 cgacgaggcg gcggccgccc tcggcgaggc ccgcgccgtc gacgaggcgg caggcacggc
    16141 accgctcctg gggcccgaac tcatcctcac cggcttccgc ggcgacctcg accggtaccg
    16201 cgagctgcgg gggtcgatgg gccgcgaagg gcggccgttc gagaccgccg gggagcacta
    16261 cgcccgagcg gtgctgaaca acgggctcgg cgactacgaa gccgctctgg acgccgcgct
    16321 ggccgcccag cgccggcacc gggcgggctc ctacgcgatc tggtccgtgt accccgaact
    16381 cgtcgaagcc gccgtacggg ccggacgcgg cgaggaggct gtcgcggccc tggagcacct
    16441 ggaggcgctg gcgcgcgcgc accccctccc gtggatcgtc gccgagtggc tccaggcgaa
    16501 ggccctcctc ggccggggtg cggactgcga cacgctgtac cggcaggcca tcggccactt
    16561 cgcccggacg cgggtacggg tgctccacgc gcgcgcccgg ctgacgtacg gggagtggct
    16621 gcgccgcgag aaccggcgcg ccgaggcccg cgacgagctg cgggcggcgt acgacatgct
    16681 gtcccgcatc ggtgcccgcg cgttcgccga gcgcgcggcc cgggaactgc gggccaccgg
    16741 cgaacagccg cgcaggcacg gcgagaaccc gctcggccgg ctcaccgcgc aggagcggct
    16801 catcgccggg aaggtcgcgg ccggggcgac gtccaaggag gtgggcgtga tgctgttcct
    16861 cagtccgcgc accatcgaca cccatctgcg caacgtgtac cgcaaactgg gcatctcctc
    16921 gcgccgccag ctccgcgaga tgtccctgtg acggcccgcc ccgggccatg tggtcacccc
    16981 ggcccgccgg acgaccggcc gaagaactcg atctccgcga tggccacctg cttctccgcg
    17041 gacgcggcgt gggccgactc gatggtgaaa cgcaccgcgg tggcctcacc gacgcggaag
    17101 gcgcggcgct gctcccccgc gcccgggtcc agggtgaggt cgcgggtctc ggtccggccg
    17161 tccttccccg tgatcgtcgc cctgacccgg tgcggcaggg cggaccggtc gagctggtcg
    17221 gcgcggacgg acacgcccgg cgtgatgacg aggtcgagca gccggaccgg gcgggcgaac
    17281 cgcacctcga tccactcgcc ctggcccgat tgcgacaccc ccgggcccca ccaggtgttg
    17341 ttgagcttgt cgaaggccag cttcggcccg tggccggggt aggagcggga ggccctgatc
    17401 ccgtccggct cgaccggagc acgcttggcg aagtggtcgc cggtggcctg gatgccgtcg
    17461 gggacgtaca gcacaccgag aatgaggagc gtcacggcga cggcggcggt gatccaggtg
    17521 ccgatccggt cgaacacacg gcggaggcgg gggcggtcgc cggcccaggg agtctcctgg
    17581 cggccgggtc cgagcaggcg gcgccaccag gggcggggta cgggcgcggg ggcggcgccg
    17641 tgctcggcga acggcatcgc gcagcggcag cagaaatggc ggtcggcggg gttcggggtg
    17701 gcacaccagg ggcacggcgc gccgtgcacc ggcccgcggg aggcggggcc gcgtacgagg
    17761 ggccgctcgg tgtcgggccg gccgggcagg acgggggtca cggcgggagc gggcgcggcg
    17821 ggggtggctg cctccgggtc cgtgacgggg acgaccaggg aacgggcgcg gtcggccgag
    17881 gggcttgccg aaggggcgct gttgtacgtc gtggacagcg ggatgccggg gtcggtgtcc
    17941 tcctcgtccg gggggccggg cgtgggtcgt ggcgcggcgg gcgtgggtcg tggcgcgccg
    18001 ggcgagggcg gtggcgcgcc gggcgttccg gtgctgtcgc ggtgcccggt gtgcccgggg
    18061 gctgccgccg aaacgccgcg gccgggcgcg gtggaggggg ctgccggggg gccggtgcgc
    18121 ccaccggccg gttcccagcg gaggacggct ccgcaggcgt cgcagaacga ctgcccgggt
    18181 tcggcgcggg tgccgcacgc actgcagtcc ggcgtggtca tgtctccgag gtcctttcgg
    18241 cggcggtgat ggtgacggtg tagggcatgt gggcggggcg ggccgcggcc acgagagcgt
    18301 ccaggcggta ggtgtcggcc cgggtgggtt cgggcagccg gagcgtgacg tggaggtggg
    18361 ggcgggcgct gccggggaac gggccgcggg ggcgcgcgct ccaggccgca ccaccgctct
    18421 ccgtgatctc cggtgcggta ccgaacgcga ggcgtacggc ttccgacagg ccgcgccggg
    18481 tgccccggac gcggtgcagg ccgaccgctg cggccacggc ggcgcgcagg cggggctcgg
    18541 gttcggtgcc gtcggtctcg gctcccaccc aggtgccgag ccaccgggcg aagtcggccg
    18601 gggtgagcgc gggatcgaag taggcgtcca ggcagtcgag cacgttcagg atcggcgcga
    18661 ggacgtcgtc gagtcctgcg acgaagcgct gggcgaggtc gtcgtcggcg aagacggccg
    18721 ggagcatcgc gccgatgggc gcggaggagc ccaggccgtc gatggagcct ctcacgggcg
    18781 gcctcctgag tacgtcggtg tcgtcacgtg ctgtccccca ccacccgcac gcggtggtcg
    18841 aaggagaaga ccagggacgg tggttgcagg tcgatgcggt cggtcgggtc gccgcgccgg
    18901 ccggtcagcg ggtcggcggg gtgcagtacg acctcgtcga ccagttccac tccggggacg
    18961 cgctgcagga tggcgaagac ctcgccggcc tggaccgggc ggccgaaggg ccagccgtgg
    19021 ccttccgcgc cgccggtgag cggatcgagg tgacggtaga gggcgtcgtg ggcccggcgg
    19081 cgtacccggt cggtgtcgac gccccggaag gcgtggacgg tggcgacgac ggtgacgccc
    19141 tggtagtagg gcgggccgac cgcgagccgg gtgccgatga ggcggcgttc gtcgaggtgg
    19201 cgggtgatgc ggtccagcag gcggtcgccg gggacgagtt gctcgaagcg gaggcggccg
    19261 cccgggtcgg ggacggcctg cggcacgacc agcacccgta ccgcgtagga cccgtgctcg
    19321 tccggtacgc cctccaggca ggtgatacgg gcggtctccg gcgcggcccg gcgggcgagt
    19381 tcctcgtagt cgcgcagcgt gacggcgcgt tcctgggcgc ggagggtgat cggggcccgg
    19441 accttcgctt ccgcgacggt ctccccgtcg actccgccgc gcgcggtctc gcggttggcg
    19501 acttcggaga cgtacgggat ggaggtgcgc aggacccgga tggcgccgcg ggtgacgttg
    19561 ccggcccggc cgccgccggt gcggtagcgg cgggcgcgga cggccgcgcc cttgggcgcg
    19621 accatgccgt actggcgcag cgtgccgtcg gcttcgcgga cggcggggcc gaaggcgatg
    19681 tcgccggtcg tggcgtcgag ggtgatgtgg tggtcgtccg gccgggacgc ggcgaagtgc
    19741 gggacgacct gccagtcctg ccacccgtcg ggtccggcgg tctggagcag caggggcggg
    19801 tcgtccccga cgacgggcgc gtgggcgagc cgccgtcgct gtccgggcag gccgctggat
    19861 tcgccgagcg cctcgtcgtg gacggtggcg gcgtgcacga cgccggtggt gccgccgatg
    19921 gtgcaggccg cggcggcgcg tacggtcggt gacgtggtgt agaagggctg gcccggcagg
    19981 ggttcggtga cgcggcagcg cagccagccc gcttcgtggc cgccggtgcg ggacagcacg
    20041 tggccgccgg ggacgtgcag gacgatgtcg ccggcgcggt tgaggccgcc ggtgccgtcc
    20101 cggtcggtct cgcagggctg ccagccgtcc tcggtccacg cctcccacac cagcggcggc
    20161 tgccgcggat cgacgccgac gccgtccacc cggctgtcga gttcgagggc gacggcgcag
    20221 cgcgggacgg ccgccgtcag accgatcagc atgcagtcgc cggggcccgg ggtttcggcg
    20281 aagcaccgta cgtgggtgcc ttcggccagt gcggtggtgt gatcggcgac gggctcgccc
    20341 cggtgctgca ccaccaggcg gctcagctcg caggggacga cggccagcgc gtgttcggtg
    20401 gcgaagacca ccgcttcctc ctgctccgtg cgcagcgtgg ccacttcggt gccgaccggt
    20461 accgcgacgg cctcctcctg gggtgcggac agccagaagg tgacgtccgt acgggctgcc
    20521 gacggcggga agagggtgac gccgacgagg tccaggaacg ccaggtggtt cttctcggga
    20581 acccggttga ggcggtagac gatctggtcg gccatgtggg cgacggtctc gacgagggtg
    20641 atgcccgggt cggagacgtt gtggtcggtc cactccggcg cgcgctgctg gatgtagcgc
    20701 ttggcgtcgt cgacgaactg ctggaagcgg cggtcgtcga ggttggggga aggcagggac
    20761 atcatcggtc gctttcgggg gagtcaccgg agccgtcgcc gacgagggcg ccgccggggg
    20821 cgtcctcctc gtgggagggg atgacgtaga acgggaagac gaggctgcgc gggttgttgg
    20881 tgccgcggat ccggtagcgg atgtcgatgt acaggacgct ctggtcggtg ccggcgctca
    20941 cctggacgtc ggtgacctcg atacgcggct cccagcggtc cagggtgacg tacacctcgt
    21001 gctggatacg gcccgcggtc tgctcgttga cgggggcgaa caccaggtcg tggatggcgc
    21061 agccgaagtc gggc
//
