LOCUS       NZ_LWKZ01000012        22539 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Streptomyces sp. CB02923 scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_LWKZ01000012
VERSION     NZ_LWKZ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CB02923
  ORGANISM  Streptomyces sp. CB02923
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1352816)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra, Yang,D., Teng,Q., Crnovcic,I.,
            Li,X., Rudolf,J.D., Lohman,J.R., Gansemans,Y., Zhu,X., Huang,Y.,
            Zhao,L.X., Jiang,Y., Van Nieuwerburgh,F., Rader,C., Duan,Y. and
            Shen,B.
  TITLE     Strain Prioritization and Genome Mining for Enediyne Natural
            Products
  JOURNAL   mBio 7 (6), e02104-16 (2016)
   PUBMED   27999165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352816)
  AUTHORS   Yan,X., Ge,H., Huang,T., Hindra,H. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2016) Department of Chemistry, The Scripps
            Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: CLC NGS Cell v. 8.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001905005.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 20:56:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,128
            CDSs (total)                      :: 8,049
            Genes (coding)                    :: 7,904
            CDSs (with protein)               :: 7,904
            Genes (RNA)                       :: 79
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 32 of 145
            Pseudo Genes (incomplete)         :: 128 of 145
            Pseudo Genes (internal stop)      :: 11 of 145
            Pseudo Genes (multiple problems)  :: 22 of 145
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 405
            Orig. end                         :: 22944
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LWKZ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22539
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22539
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22539
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12539](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12539)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    706..719
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.63"
                     /tool="antismash"
     misc_feature    complement(716..730)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.96"
                     /tool="antismash"
     misc_feature    complement(868..883)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.31"
                     /tool="antismash"
     misc_feature    1071..1080
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    1089..1098
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     misc_feature    1173..1188
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.63"
                     /tool="antismash"
     misc_feature    1179..1199
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.53"
                     /tool="antismash"
     misc_feature    1228..1241
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.63"
                     /tool="antismash"
     gene            1373..2239
                     /locus_tag="A6A06_RS11685"
                     /old_locus_tag="A6A06_06225"
     CDS             1373..2239
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572294.1"
                     /locus_tag="A6A06_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06225"
                     /product="hypothetical protein"
                     /protein_id="WP_073761163.1"
                     /transl_table=11
                     /translation="MTKKTRLRVARIAAGAVIAAGASLTAAGAASAVGTEQTAGSGGSG
                     GGLGAILDDLLGGGDTGGSGGGEIGGSETGGSETGGSETGGSETGGSETGGSETGGSET
                     GGSETGGQSGNQTGGSETGGNQTGGQSGNQTGGSETGGNQTGGQSGNQTGGNQTGGQSG
                     NQTGGNQTGGNQTGGNQTGGNGSGGSDGSTGSTSNGSTGGSDDGTGTGTDNEGSKPIEQ
                     PGEGNEQIVNTPGQPQQQAKGGELAETGASGTTFLLVGAATMIAGGIGFRLMPRLINKN
                     GGGAAAA"
     gene            complement(2396..2584)
                     /locus_tag="A6A06_RS11690"
                     /old_locus_tag="A6A06_06230"
     CDS             complement(2396..2584)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990616.1"
                     /locus_tag="A6A06_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06230"
                     /product="hypothetical protein"
                     /protein_id="WP_073761164.1"
                     /transl_table=11
                     /translation="MTYDRLVCANCAAPVNEGRCPVCRASRERLQESGLFGQVTPAALV
                     ALLVALIALAVLVHQAA"
     gene            2880..3569
                     /gene="ftsE"
                     /locus_tag="A6A06_RS11695"
                     /old_locus_tag="A6A06_06235"
     CDS             2880..3569
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349025.1"
                     /locus_tag="A6A06_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06235"
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="WP_073761165.1"
                     /transl_table=11
                     /translation="MIRFDNVSKTYPKQNRPALRDVSLEIERGEFVFLVGSSGSGKSTF
                     LRLLLREERASHGAVHVLGKDLAKLSNWKVPQMRRQVGTVFQDFRLLPNKTVGQNVAFA
                     LEVIGKPRGQIRKTVPEVLDLVGLGGKDERMPGELSGGEQQRVAIARAFVNRPLLLIAD
                     EPTGNLDPQTSVGIMKLLDRINRTGTTVVMATHDQQIVDQMRKRVMELEKGRLVRDQSR
                     GVYGYQH"
     gene            3602..4513
                     /gene="ftsX"
                     /locus_tag="A6A06_RS11700"
                     /old_locus_tag="A6A06_06240"
     CDS             3602..4513
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572291.1"
                     /locus_tag="A6A06_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06240"
                     /product="permease-like cell division protein FtsX"
                     /protein_id="WP_073761166.1"
                     /transl_table=11
                     /translation="MRAQFVLSEIGVGLRRNLTMTFAVIVSVALSLGLFGASLLMRDQV
                     GTMKGYWYDKVNVSVFFCNKNDTETGANCAKGAATEQQKNDIKAELDRLPIVQSVTHET
                     SDEAFKHYKEQFGDTPIAGLVTPDQFQESFRVKLKDPTKYEVIKSAFSERPGVQEVQDQ
                     RDTVEPLFNLLNGMNIAALVVMALMLVVALMLIVNTVRVSAFSRRRETGIMRLVGASSF
                     YIQMPFILEAAIAGLLGAVFACVLIVGGKWVLINNWLAARIQVINFIGWDSVVAVLPLV
                     LLIGLLMPALAAFFALRKYLKV"
     gene            4581..5780
                     /locus_tag="A6A06_RS11705"
                     /old_locus_tag="A6A06_06245"
     CDS             4581..5780
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572290.1"
                     /locus_tag="A6A06_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06245"
                     /product="S41 family peptidase"
                     /protein_id="WP_073761167.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 5.9e-40, bitscore:
                     132.7, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPCLFARPRRSRRGAALTLVFVSVLATGAAAGTWEESGPPSGE
                     RRISGRAASEADRVHRTQRAGRHAAGPHTDGSGAADDVVSRSGDRWSTAFSAREYEDFE
                     QELNGEYVGVGLWLRQAADGRALVSRVRPGSPAAAAGLRAGDDLRAVDGVPSRGSQVTE
                     VVARLRGGAGPAAGGPEPGAGSGVALELRRGTRQWTETLRRARLRDQNVITDRPDGPDG
                     PTRIKVGAFSSGTGEEVRRAVRAASPRGGVLLDLRGNTGGLVREAVTAASAFLDGGLVA
                     TYDVRGSQRALYAKDGGNTQIPLAVLVDGGTMSAGELLAGALQDRGRAVLVGSPTFGKG
                     SVQLPSELPDGSVAELTVGHYRTPSGRGVDDRGITPDLLAADDAPARARTVLSGLGGGA
                     "
     gene            5799..6308
                     /gene="smpB"
                     /locus_tag="A6A06_RS11710"
                     /old_locus_tag="A6A06_06250"
     CDS             5799..6308
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="smpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986511.1"
                     /locus_tag="A6A06_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06250"
                     /product="SsrA-binding protein SmpB"
                     /protein_id="WP_073761168.1"
                     /transl_table=11
                     /translation="MAKANKKKNKKDDGTGRKLIAQHKKARHDYLILDTYECGLVLTGT
                     EVKSLRQGRASLVDGFVQIDRGEAWLHNVHIPEYAQGTWTNHSARRKRKLLLHRVEIDR
                     LESKSQETSHTIVPLALYFTNGRVKVEIALAKGKKEYDKRQTLREQQDRREADRVISAV
                     KRRERA"
     tmRNA           6464..6833
                     /db_xref="RFAM:RF00023"
                     /gene="ssrA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="A6A06_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="A6A06_06255"
                     /product="transfer-messenger RNA"
     gene            6464..6833
                     /gene="ssrA"
                     /locus_tag="A6A06_RS11715"
                     /old_locus_tag="A6A06_06255"
     gene            complement(6931..8232)
                     /locus_tag="A6A06_RS11720"
                     /old_locus_tag="A6A06_06260"
     CDS             complement(6931..8232)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091247.1"
                     /locus_tag="A6A06_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06260"
                     /product="MFS transporter"
                     /protein_id="WP_073761169.1"
                     /transl_table=11
                     /translation="MILFLASRPVTAPPVPPVRRRRRRSPAALRRVLGPYGRIFTVPGA
                     RAFTAANLLARLPMGMFGVSAILMIAGSRGSYALAGAVTATGLAATAVAGPWTARLVDR
                     YGQARVAVPATALAVLGSLALLLCVHFGAPSWTLFAAYACTATTPNTGGMARARWAHLL
                     RNDAAALHTANSFEQAADEVCFMLGPVLAAFLCTGLFPEAGTLTGAVLLLTGVLLFAAQ
                     RRTEPPAAPASASARHGAGPLVTSLLPLLLTFLATGAVFGSLEVVTIGFTDAHGQRAAA
                     GALLALQAAGSCAAGLLYGVLRPAGPAGRRFLWCVAAMAVLMWLPFTAAGAGGGVLLGA
                     ALLLAGMATAPTMVTGMGLIQSRVPAGRLNEGMTLAVTALLTGIAAGSAGGGWAVQHLP
                     RGAAAGYTAPAAAAALALAAAVAAHAVRAARRPA"
     gene            8357..9328
                     /locus_tag="A6A06_RS11725"
                     /old_locus_tag="A6A06_06265"
     CDS             8357..9328
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986510.1"
                     /locus_tag="A6A06_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06265"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_073762078.1"
                     /transl_table=11
                     /translation="MPRDLDPRLLRAFTAVADELHFTRAAARLYVAQQALSRDIRRLER
                     EVGADLFDRTTRRVALTEDGARLLPYARRVLAAHDDLAAAFHAPDDRPLLVDVGVPIGT
                     AHAVLEEARRLAPACELVARFHSGLTGAAAELAAGRLDVSFGRVAGLPPAVRARLDHRP
                     VRFEPMAVLLDEGHPLASRPAVPLSALAGETLYAGAGNAQTAEWTDLATRLFAGRDIAM
                     AAPFPEIEGSAEFMRVVRKQGWSVLASVEFIDVPGMALRPVTDPVPLSPISLVWRRGLR
                     HAGLDALRTACRSLAARHGWLRRPAGPDWLPEEDAALMAHGG"
     gene            9419..9940
                     /locus_tag="A6A06_RS11730"
                     /old_locus_tag="A6A06_06270"
     CDS             9419..9940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091249.1"
                     /locus_tag="A6A06_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06270"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_242440695.1"
                     /transl_table=11
                     /translation="MRKRPLMVAALAVLVLSGGLVACDEPRVDALHASCTTKDLRWKVT
                     VLKKKARSTHREGRLSAVNTGARECVFRGFPDFLVRVGKGPEAGGVGHGRARAVSLPAG
                     SGVVVDLRYRDAERGHPAPADCLVGNGSAEVTAPRDTQGTLVRAWDESGRRARLDVCDN
                     VIRMEPPRKA"
     gene            complement(10001..10408)
                     /locus_tag="A6A06_RS11735"
                     /old_locus_tag="A6A06_06275"
     CDS             complement(10001..10408)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986508.1"
                     /locus_tag="A6A06_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06275"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_073761170.1"
                     /sec_met_domain="PF13471 (E-value: 4.5e-27, bitscore: 90.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPVSTGAPARLSFAERCAALGCVAAARLLTCCSPRTLCRALES
                     VRRGAGPATAPEAARARHAVVTVSVRCAGNGCLQRSVATALLCRLRGRWPQWCTGVRTE
                     PFRAHAWVAVDGHPVGEPDDTRLYHPLLSVP"
     gene            complement(10405..10662)
                     /locus_tag="A6A06_RS11740"
                     /old_locus_tag="A6A06_06280"
     CDS             complement(10405..10662)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056407.1"
                     /locus_tag="A6A06_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06280"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_073761171.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.3e-21,
                     bitscore: 70.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.7e-11, bitscore: 38.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFALAPHVSSVRTPGGMVLLNARTGRYWQMNNTGAFVLEHLLAG
                     GTCASAADELRYRHPSAADRVAADAVALLESLQSAKLVTS"
     aSDomain        complement(10411..10659)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A6A06_RS11740_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.50E-22"
                     /identifier="RREFam002.1"
                     /label="A6A06_RS11740"
                     /locus_tag="A6A06_RS11740"
                     /protein_end="84"
                     /protein_start="1"
                     /score="70.4"
                     /tool="antismash"
                     /translation="AFALAPHVSSVRTPGGMVLLNARTGRYWQMNNTGAFVLEHLLAGG
                     TCASAADELRYRHPSAADRVAADAVALLESLQSAKLVT"
     gene            complement(10668..12539)
                     /locus_tag="A6A06_RS11745"
                     /old_locus_tag="A6A06_06285"
     CDS             complement(10668..12539)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986506.1"
                     /locus_tag="A6A06_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06285"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_073761172.1"
                     /sec_met_domain="Asn_synthase (E-value: 8.8e-33, bitscore:
                     110.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFVVFPDHPATGPLCLSLRRDPTVRTVPHPSGRAWVMGHWTDDE
                     AVAAGSGPDRLLLLGTASADSGTLDRLLRRLRRLDDLDSRIRELPGSFFLLAAMGPRIR
                     CQGSLSTIRQLHHAGINGVTVAASRPQDLAALAREAAAAGLPTGAPGLGSVDEESLALR
                     LLAPFAPFPLAQRPAWRAVHAVPPGHCLTLGADGRHGTVRWWRPPEPDRWLEDAAESVR
                     DALTEAVRVRTRGPAVSADLSGGMDSTSLCFLAARDAPRLITTAWGCRDEANDDTVWSD
                     RGAALLRTAEHLPLPYADAPTWYTPPQPGLGDPAGPLSVVRESARLAHQAAIVAARGSR
                     RHLVGVGGDELFSPRPVALNSLARTDFRSAARRACAARRLGRWTLVDTLRTLFGGVPYP
                     QWLESCADRIVPGVRSGDSGADWEVVPAMPPWAHPDAVATVRRLVRDAAAGAPEPFAPL
                     RCQHETLRAAARAGEIVRGADALTAPHGVTFEAPFLDDNVIEAALTVRLVDQVAVGSYK
                     PLLSAAMRGILPDALRARGTKGEHSAEVYAGLRRHRRALSALCDDSRLAGLGLIRPEAL
                     RTALTSLQPRSHTLHPLDPTLAAEYWLRSLQESQAPARPTVPAAEGA"
     gene            complement(12937..13080)
                     /locus_tag="A6A06_RS11750"
     CDS             complement(12937..13080)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140851.1"
                     /locus_tag="A6A06_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_199930836.1"
                     /transl_table=11
                     /translation="MPDIQEQPESVEYEAPELAEAGDFAELTLGFHGHHWDTFGGRGHG
                     WW"
     CDS_motif       complement(12994..13080)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MPDIQEQPESVEYEAPELAEAGDFAELTL"
                     /locus_tag="A6A06_RS11750_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12937..12993)
                     /prepeptide="core"
                     /locus_tag="A6A06_RS11750_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="2116.2"
                     /monoisotopic_mass="2114.9"
                     /core_sequence="GFHGHHWDTFGGRGHGWW"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MPDIQEQPESVEYEAPELAEAGDFAELTL"
                     /leader_location="[12993:13080](-)"
     gene            13399..14799
                     /locus_tag="A6A06_RS11755"
                     /old_locus_tag="A6A06_06290"
     CDS             13399..14799
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004571961.1"
                     /locus_tag="A6A06_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06290"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_073761174.1"
                     /transl_table=11
                     /translation="MAGTGTATGEAAARTAGRGAGRWIERWDPEDESFWRHHGRRIARR
                     NLVLSIVCEHIGFSVWSLWSVMVLFMGPQYGIDAAGKFFLVAVPTLVGAVLRVPYTFAV
                     ARFGGRNWTVCSVALLLVPTAAAVFALRPGTSYTVFLLVAALAGVGGGNFASSMTNINS
                     FYPLRKKGWALGLNAGGGNIGVPVVQLLGLLVIATAGADRPRLVLAVYLPLIVVAAVLA
                     ALFMDNLRPVRNDTGAAREAARDPHTWIVSLLYVGTFGSFIGYSFAFGLVLQTQFARTP
                     LQAASLTFIGPLLGSLVRPVGGRLADRYGGARITLANFAAMALATGVVILASARHSLEV
                     FLAGFVVLFVLSGLGNGSTYKMIPGIFQAKALAKGLTGEAVAAHGRRLSGAVMGLTGAV
                     GALGGLGVNLAFRQSFQSAGTGTPAFVAFLGCYALCSAVTWAVYLRRTAATVAVRDREA
                     AEPALAEV"
     gene            14940..16220
                     /locus_tag="A6A06_RS11760"
                     /old_locus_tag="A6A06_06295"
     CDS             14940..16220
                     /EC_number="4.2.1.75"
                     /GO_function="GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004571960.1"
                     /locus_tag="A6A06_RS11760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06295"
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="WP_073761175.1"
                     /transl_table=11
                     /translation="MHEGEQDERRDDGGTGRGGRQHDGRGAADHGAAGQGDGPGDGDRG
                     RTAAATDVRPLDGFTVGVTAARRAEELGALLERRGAQVVHAPALRIVPLPDDAELLAAT
                     KDLIDRAPDVVIATTAIGFRGWIEAAEGWGLGEALLARLGAVELLARGPKVKGAIRAAG
                     LTEKWSPVSESLAEVLDRLLEEGVHGRRVVIQLHGEPLPGFVESLRAGGAEVVGVPVYR
                     WMPPADIGPVDRLLDAAVTRGLDAITFTSAPAAASLLRRAEERGMRDGLLRALRHDVLP
                     ACVGPVTALPLEAHEVTTYQPERFRLGPLVQLLCQELPGRVRPLTVAGRRVEIRGQAVL
                     VDGNLRPVPPAGMALLRALARRPGWVVSRADLLRALPGAGRDEHAVETAMARLRGALGA
                     PKLIQTVVKRGYRLALDPRLGAKYGDE"
     gene            complement(16284..17060)
                     /locus_tag="A6A06_RS11765"
                     /old_locus_tag="A6A06_06300"
     CDS             complement(16284..17060)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004571959.1"
                     /locus_tag="A6A06_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06300"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_073761176.1"
                     /transl_table=11
                     /translation="MSAKTLLKNRSSLTHKVRYAVSNPARIAPYLRRTARDSWLRLKHP
                     DHVAYYRAVMASDTSRNPEAAVGSRSHERWLALGDMQFTYLKEHGLRPDTRMLDIGCGN
                     LRAGWRFIAHLDTGNYYGIDISPDILISAKKTLATYELQDKLPHLTITQDLTFDFLPDA
                     HFDVVHAHSVFSHSPLSVIDQSFRHVGRILAPGGFFDFTFDRTEGAEHQVLREDFYYRT
                     GTLLALARKHGLEARFMEDWETRPHGQSKIRVTNPT"
     gene            17203..17835
                     /locus_tag="A6A06_RS11770"
                     /old_locus_tag="A6A06_06305"
     CDS             17203..17835
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091255.1"
                     /locus_tag="A6A06_RS11770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06305"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_073761177.1"
                     /transl_table=11
                     /translation="MAAPFDLRFDCGRICLDLMATTGRTAERLAGPEHLAAWLVGSGVV
                     PGSTQLGAVDRGWVVRFRMLRELLRRVIHDELRGRAADGDLRLLNAAAAAAPVPPARAV
                     RTDDGGLVRAFAGPPDCAGLLAAVARDAIAMLTDAVTRGQLRQCEGESCSLVYLDTSRG
                     RRRRWCSSEVCGNRERVARHRRRATRRELSGQPPVVRPAVRTVPTKT"
     misc_feature    complement(17249..17263)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.48"
                     /tool="antismash"
     gene            complement(17784..18734)
                     /locus_tag="A6A06_RS11775"
                     /old_locus_tag="A6A06_06310"
     CDS             complement(17784..18734)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019095.4"
                     /locus_tag="A6A06_RS11775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06310"
                     /product="DUF3455 domain-containing protein"
                     /protein_id="WP_079193963.1"
                     /transl_table=11
                     /translation="MSRDRAIAAACAAAAVAVALMAPPAHAAQTAQAGGGGAVSFVSSL
                     SAENEASGTGDRDGRGLAFLRLRGGRLSFALSFRGVATPVAAVLREAGKGAGGPVRIPL
                     FTGRLSAGKTSVSGTVEISGRRVLDALRRQPNSFSFNLLTERFPHGAIRGRLHALAEPV
                     DADRALRHSVRAPVVHGAQIYACTRQGDGSYAYTQRDVRALLEGGIAHFFAAPGPKGPP
                     VWVAPDRSAVTGTVRSKTPNGAGNIPELALDARRSGPPDGRLGQVGEILRLNTAGGVAP
                     GGACDPAAHPEAAVPYRADYVFVGTVRTAGRTTGG"
     misc_feature    complement(19148..19166)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.76"
                     /tool="antismash"
     gene            19221..19742
                     /locus_tag="A6A06_RS11780"
                     /old_locus_tag="A6A06_06315"
     CDS             19221..19742
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056398.1"
                     /locus_tag="A6A06_RS11780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06315"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_199930837.1"
                     /transl_table=11
                     /translation="MADSTSPDEELMRALYEEHAGPLLAFVLRLVAGDRHRAEDVVQET
                     LLRAWRNAGQLQRATGSVRPWLVTVARRIVIDSHRSRQARPQEVDAAPLESMPAADEID
                     RALRLMTITEALGDLSAAHREALIETYFKGRTVSEAAEVLRVPAGTVRSRVFYALRSLK
                     LSLEERGVTA"
     gene            19742..20479
                     /locus_tag="A6A06_RS11785"
                     /old_locus_tag="A6A06_06320"
     CDS             19742..20479
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717475.1"
                     /locus_tag="A6A06_RS11785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A6A06_06320"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_073761179.1"
                     /transl_table=11
                     /translation="MRPTEPVEHTDVGAYALGVLDAAEAARFEEHLAGCDRCAAELDDL
                     MGLPPLLADAREAAPDPEAVTPVPGPGLLDGLLAEVGAVRRTRRRRRLYLVAAAAVLVA
                     GGPLTTYALTAGDTDETPEHLASYARTMYEHGEKAGTVDPVTKVAASVSMERKPWGTHV
                     ALKLGNVKGPLTCDLVAIGKNGAEQTVTTWAVPAGGYGLKDGATKWNKEPLYTHGGAAM
                     NRSTIDRFEVRTLDGRRLAEIKV"
     misc_feature    20894..20907
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
ORIGIN
        1 aggccgcggc gccgtccctc tgggacgacc cggagagcgc gcagaagatc accagtcggc
       61 tgtcctatct ccagggccag ctgcgccggg ccgaggaact gcgcggccgg gtcgacgacg
      121 tcggtgtgct cttcgagctc gccgaggccg agggggacga cgagacccgc gccgaggccg
      181 agggcgagct ggccgtcgtc cgcaaggcgg tcgacgagct ggaggtccgc accctgctct
      241 cgggcgagta cgactcccgc gaggccgtcg tcaacatccg cgccgaggcc ggtggcgtgg
      301 acgccgccga cttcgccgag aagctccagc gcatgtacct gcgctgggcc gagcggcacg
      361 gctacaaggc cgaggtgtac gagacctcgt acgccgaaga ggccggcatc aagtcgacca
      421 ccttcgccat ccaggtgccg tacgcctacg gcacgctctc cgtcgagcag ggcacccacc
      481 gcctcgtgcg gatctcgccc ttcgacaacc agggccgccg ccagacgtcc ttcgcgggcg
      541 tcgaggtgct gccggtggtc gagcagaccg accacatcga gatcgacgag tccgagctgc
      601 gcgtcgacgt gtaccgctcc tccggccccg gcggccaggg cgtcaacacg accgactccg
      661 cggtgcgtct gacgcacatc ccgaccggca tcgtcgtctc ctgtcagaac gagcgttcgc
      721 agattcagaa caaggcgacc gcgatgaacg tcctccaggc gaagctgctc gaacgccgcc
      781 gccaggagga gcaggccaag atggacgcgc tcaagggcga cggcggcaat tcctggggaa
      841 accagatgcg gtcgtacgtt ctgcacccgt accagatggt caaggacctg cgtaccgagt
      901 tcgaggtcgg caatccgcag ggcgtgctcg acggcgacat cgacggcttc ctggaggcgg
      961 gtatccgctg gcgcaagcag caggagcagc agaagtaaca tccggcccgg cgtaaggccg
     1021 cccgaaaagg ccgggaaaac agccgggaaa tgcaccggga aatcaactgt cgctttttga
     1081 gcggcagttg atttttgttg tcgtgggacg aggtggcggt ttggtcacag tcatacgtcc
     1141 atggaccccg caactcacct caattcggtc atcgcacctt tatttgacct tgacgatgat
     1201 gtgagaactg ggaatggtgg tacgtggcat acgtatgtct ggggcgtgcg tgtgaacggg
     1261 gaactgagtg caacggccgc agggcggtac ggcgactcgc ctacccgggt cggccgctgc
     1321 cccgaacagc gatgctccat ggacgagtag agctactggg ggtagcaggc acatgacgaa
     1381 gaagacgcgg ctgcgcgtag cgcgcattgc ggccggcgcg gtgatcgcgg ccggtgcgtc
     1441 gctcaccgcc gcaggcgccg cctcggcggt cggcaccgag cagacggcag gctccggcgg
     1501 ctcgggcggc ggcctgggtg ccatcctcga cgatctcctc ggcggcggcg acaccggcgg
     1561 cagcggcggt ggcgaaatcg gcggcagcga gaccggtggt agcgagaccg gcggcagtga
     1621 gaccggtggt agcgagaccg gtggtagcga gaccggcggt agtgagaccg gcggtagtga
     1681 gactggcggc agcgagaccg gcggtcagag cggcaaccag accggtggta gcgagaccgg
     1741 tggcaaccag accggtggcc agtccggcaa ccagaccggt ggtagcgaga ccggtggcaa
     1801 ccagaccggt ggccagagcg gcaaccagac cggtggcaac cagaccggcg gtcagagcgg
     1861 caaccagacc ggtggcaacc agaccggtgg caaccagacc ggtggcaacc agaccggcgg
     1921 caacggctcc ggcggttcgg acggctccac cggcagcacc tccaacggca gcaccggtgg
     1981 cagcgacgac ggcaccggca ccggcaccga caacgagggc agcaagccga tcgagcagcc
     2041 cggcgagggc aacgagcaga tcgtcaacac gcccggccag ccgcagcagc aggccaaggg
     2101 tggcgagctg gcggagaccg gtgcctccgg caccaccttc ctgctcgtcg gcgcggcgac
     2161 gatgatcgcc ggtggcatcg gcttccgcct gatgccgcgc ctgatcaaca agaacggtgg
     2221 cggcgcggcc gcggcctgac accaggcccg ccccgtaccc ggggcagcgc atgacgaagg
     2281 gcccggagcg cgagcggcgc tccgggccct tcggcgtccc tgcgtcatcg gtgtgcgccc
     2341 gtcggcgcac caggcggagc gaggctccgt acgcgctgcg tcaccgggcg ccgcctcagg
     2401 cggcctggtg caccagcacc gcgagggcga tcagcgccac cagcagcgcc accagggccg
     2461 cgggcgtcac ctgcccgaac agcccgctct cctgcagccg ttccctgctg gcccggcaca
     2521 cggggcagcg gccctcgttc acaggggccg cgcaattggc gcacaccagc cggtcgtacg
     2581 tcatgcgacc tcctcctcaa ccgctgcaac gcgcaaggga ccacgatggt tccctctacc
     2641 actgtgccag cttgtcggct gaacggcgcg ccccggtcac cttccggcct tttcggcggc
     2701 accgctcggg tccacgggcc ggaatgtgct ccttttgtcc ccgtagatgc cgtgaataaa
     2761 cgcaccaacc ccgaacggcg actgcgcctt cgcgtgagac tcgcgtaggg tcacgctcac
     2821 cgacgggagc cacaacaggg gcatcccgtg ccgctaccca ggtcgaccgt ggtgcatcag
     2881 tgatccgatt cgacaacgtc tccaagacct acccgaagca gaaccgcccc gccctcaggg
     2941 atgtctccct ggagatcgag cgcggcgagt tcgtcttcct ggtgggctcc tcgggctccg
     3001 gcaagtccac cttcctgcgc ctgctcctgc gcgaggagcg cgccagccat ggcgccgtgc
     3061 acgtgctggg caaggacctc gcgaagctgt ccaactggaa ggtgccgcag atgcgccgcc
     3121 aggtgggcac cgtcttccag gacttccggc tgctccccaa caagacggtg gggcagaacg
     3181 tcgccttcgc cctcgaagtc atcggcaagc cgcgcggcca gatccgcaag acggtccccg
     3241 aggtcctcga cctcgtcggc ctcggcggca aggacgagcg gatgccgggc gagctgtccg
     3301 gtggtgagca gcagcgcgtc gccatcgcgc gggcgttcgt caaccgaccg ctgctgctca
     3361 tcgcggacga gcccaccggc aacctcgacc cgcagacctc ggtcggcatc atgaagctgc
     3421 tggaccggat caaccggacc ggtacgacgg tggtcatggc cacccacgac cagcagatcg
     3481 tcgaccagat gcgcaagcgc gtcatggaac tcgaaaaggg ccggctcgtg cgcgaccagt
     3541 cgcgcggcgt gtacggctac cagcactaag cgtgtacggc ccccagcact gaaaggacgc
     3601 catgcgcgcc cagttcgtcc tgtcggagat cggcgtcggt ctccgccgga acctcacgat
     3661 gaccttcgcg gtcatcgtct ccgtagccct ctccctcggc ctgttcggcg cctcgctgct
     3721 gatgcgcgac caggtcggca cgatgaaggg ctattggtac gacaaggtca acgtctccgt
     3781 cttcttctgc aacaagaacg acaccgagac cggtgccaac tgcgccaagg gcgcggccac
     3841 cgagcagcag aagaacgaca tcaaggccga gctggaccgc ctgccgatcg tgcagagcgt
     3901 gacgcacgag accagcgacg aggcgttcaa gcactacaag gagcagttcg gcgacacgcc
     3961 catcgcgggc ctggtcacgc cggaccagtt ccaggagtcc ttccgggtca agctcaagga
     4021 cccgacgaag tacgaagtga tcaaatcggc gttctccgag cggcccggcg tccaggaggt
     4081 gcaggaccag cgggacaccg tcgagccgct gttcaacctg ctcaacggca tgaacatcgc
     4141 cgcgctggtg gtgatggcgc tgatgctggt ggtggcgctg atgctgatcg tcaacaccgt
     4201 gcgggtgtcg gcgttcagcc ggcggcggga gaccgggatc atgcgcctgg tgggcgcctc
     4261 cagtttctac atccagatgc cgttcatcct ggaggcggcc atcgcgggcc tgctgggcgc
     4321 ggtgttcgcc tgcgtgctga tcgtcggcgg caagtgggtc ctgatcaaca actggctggc
     4381 cgcgcgcatc caggtcatca acttcattgg ctgggattcg gtcgtggcgg tgctgccgct
     4441 ggtgctgctg atcggcttgt tgatgccggc gctcgccgcg ttcttcgcgc tccgcaagta
     4501 cctcaaggtg tgatgtgtgc caagggcgcc gtacggtcaa ctccccgtac ggcgcttctt
     4561 tctggcctac actcaccggc atgacgggcc cgtgtttgtt cgcccggccc cgccgcagcc
     4621 gccgcggggc ggccctgacg ttggtcttcg tcagcgtgct ggccaccggt gcggcggcgg
     4681 gcacctggga ggagagcgga cccccctcgg gcgaacggcg gatatccggg cgtgcggcct
     4741 ccgaagccga ccgcgtccac cggacgcagc gcgccggccg gcacgccgcg gggccgcaca
     4801 cggacggctc cggcgccgcg gacgacgtcg tcagccgcag cggcgaccgc tggtcgaccg
     4861 ccttctcggc ccgcgagtac gaggatttcg agcaggagct gaacggcgag tacgtcggcg
     4921 tcggcctgtg gctgcggcag gcggcggacg gccgcgccct ggtctcccgg gtacggcccg
     4981 gcagtcccgc ggcggcggcc ggtctgcgcg ccggcgacga cctgcgcgcg gtggacggcg
     5041 tgccctcgcg gggcagccag gtcaccgagg tcgtggcgcg gctgcgcggc ggcgccgggc
     5101 cggccgccgg gggccccgag ccgggcgccg ggagcggcgt cgccctggag ctgcggcgcg
     5161 gcacgcggca gtggaccgag acgctgcgcc gggcccgcct gcgcgaccag aacgtgatca
     5221 ccgaccgccc cgacggcccg gacggcccca cccgcatcaa ggtcggcgcc ttcagcagcg
     5281 gtacgggcga ggaggtccgc cgggcggtgc gcgcggcctc cccgcgcggc ggcgtgctgc
     5341 tggacctgcg cggcaacacc ggcggcctgg tgcgcgaggc ggtcaccgcg gcctccgcct
     5401 tcctggacgg cggcctggtc gccacgtacg acgtccgcgg cagccagcgc gccctgtacg
     5461 cgaaggacgg cggcaacacg cagatccccc tcgcggtgct cgtggacggc ggcacgatga
     5521 gcgccggcga gctgctggcc ggggcgctcc aggaccgcgg ccgtgcggtc ctggtcggct
     5581 caccgacctt cggcaagggc tcggtgcagc tgcccagcga gctgccggac ggctcggtcg
     5641 ccgagctgac cgtcggccac taccgcaccc cgtcgggccg cggggtggac gaccgcggca
     5701 tcaccccgga cctgctcgcc gcggacgacg ccccggcccg tgcccgcacg gtattgagtg
     5761 gcttgggggg cggggcgtag tgcgaaaatg gctccactat ggctaaggcg aacaagaaga
     5821 agaacaagaa ggacgacggg accggccgca agctcatcgc ccagcacaag aaggcgcggc
     5881 acgactacct catcctggac acgtacgaat gcgggctggt gctgaccggc accgaggtca
     5941 agtcgctgcg gcagggccgg gcgtccctgg tggacggttt cgtgcagatc gaccgcggtg
     6001 aggcgtggct gcacaacgtg cacatcccgg agtacgccca gggcacgtgg accaaccaca
     6061 gcgcgcggcg caagcgcaag ctgctgctgc accgcgtgga gatcgaccgg ctggagtcga
     6121 agtcgcagga gaccagccac acgatcgtgc cgctggcgct gtacttcacg aacggccgtg
     6181 tgaaggtcga gatcgcgctc gccaagggca agaaggagta cgacaagcgg cagacgctgc
     6241 gcgagcagca ggaccgccgc gaggcggacc gggtgatctc ggcggtcaag cggcgcgagc
     6301 gggcctgagg gcctgaaggc ctgagggccc cagcggcccg ggtggcccgc gcgccggccg
     6361 tccgccgtac gggcaggaat acgctggcat cgtcgcgcgt tggtcacgta cgatgggcta
     6421 cgcaccgcac gccggtgcag gcaccacctt gaaaaaacaa catggggatg atcggtttcg
     6481 acagcggatg tcgaagcagg ggaagcgagc cgaggaagcg gcaatgatct cgtaaaccct
     6541 atgtcgcaaa aaataatcgc caacaccaag cgcgattcct tcgccctcgc tgcctaagta
     6601 gcgacttgcg aagtgtcagc ccggggctgt tcccgacccg gatcctggca tcagctaggg
     6661 gactaaactt ctgggtccgg tcacggggcc caggaggaaa tcaaacagtg actgagcccg
     6721 tcggagacgt gtccgcgaga tctccggggc tgagaaaatc gcagcggact gcgctcggag
     6781 aagccctgtt tccgcaccgt tggacgcggg ttcgattccc gccatctcca ctcgacggag
     6841 aaaccggagg ccctggcccc cggacccgtc accccatgtg aggcgaaggc cccgctgccc
     6901 aggcagcggg gccttcgtcg ttcccgctgc tcaggccggc cgccgggcgg cccgtacggc
     6961 gtgggcagcc acggccgccg ccagggccag cgcggcggca gcggccggtg cggtgtagcc
     7021 cgccgcggcg ccccggggca ggtgctgcac tgcccagccg ccgcccgccg agcccgccgc
     7081 gataccggtc agcagcgcgg tcacggccag cgtcatgcct tcgttcaggc ggcccgccgg
     7141 aaccctcgac tggatcagcc ccatgccggt gaccatggtc ggcgccgtgg ccatcccggc
     7201 gagcagcagc gccgctccca gcaggacccc gccgcccgcg cccgcggccg tgaaaggcag
     7261 ccacatcagt acggccatgg cggcgacaca ccacaggaag cggcggcccg ccggtccggc
     7321 cgggcgcagc accccgtaca ggagccccgc cgcacaggac ccggccgcct ggagggcgag
     7381 cagcgcgccc gccgcagcgc gctgtccgtg ggcgtccgtg aagccgatcg tgacgacctc
     7441 cagcgagccg aagaccgccc cggtggcgag gaaggtcagc aggaggggca ggagcgaggt
     7501 cacgagcggc ccggcgccgt ggcgggcgga cgcggacgcg ggtgcggccg gcggctccgt
     7561 acggcgctgg gcggcgaaca gcagcacccc cgtcagcagc aggaccgcgc cggtcagcgt
     7621 gcccgcctcc gggaacagcc cggtgcacag gaaggccgcc agcaccgggc cgagcatgaa
     7681 gcacacctcg tcggccgcct gctcgaagga gttggcggtg tgcagcgcag ccgcgtcgtt
     7741 ccggaggagg tgggcccagc gggcgcgtgc catgccgccg gtgttcggtg tggtcgcggt
     7801 gcaggcgtac gcggcgaaca gcgtccagga cggcgcaccg aagtggacgc acagcagcag
     7861 ggcgagtgat ccgaggaccg ccagtgccgt cgcggggacg gcgaccctgg cctgtccgta
     7921 ccggtcgacg agccgcgccg tccacggccc ggcgaccgcc gtcgccgcca gccccgtcgc
     7981 ggtgacggcc ccggccagcg cgtacgagcc gcgcgacccg gcgatcatca ggatcgcgct
     8041 gacgccgaac atgcccatgg gcagccgggc gaggaggttg gcggcggtga aggcacgggc
     8101 gccgggcacg gtgaagatcc gtccgtacgg cccgagtacg cgccggagcg cggcggggga
     8161 gcggcggcgc cgacggcgga cgggcgggac gggcggggcg gtcaccggcc gggaggcgag
     8221 gaagaggatc acgcaaccac ggtcgccgcg cggcccgttc cgcgtccaac acctgctccg
     8281 tccccattca cacacgcccg ttgtcaatca cgcagacgcg tccgggaccc gcacgccccg
     8341 gtggcacgat gtgcccgtgc cccgagacct cgacccgcgc ctgctccgcg ccttcaccgc
     8401 cgtcgccgac gaactgcact tcacccgcgc cgccgcccgg ctgtacgtcg cccagcaggc
     8461 actgagccgc gacatccggc ggctggaacg ggaggtgggc gcggacctct tcgaccgtac
     8521 gacgcgccgg gtcgccctca ccgaggacgg cgcccggctg ctcccgtacg cgcgccgggt
     8581 actggccgcc cacgacgacc tggccgccgc cttccacgcc cccgacgacc gtcctctgct
     8641 ggtcgacgtc ggtgtcccca tcggcacggc gcacgccgtc ctggaagagg cccgccgcct
     8701 ggcccccgcc tgtgaactcg tcgcgcgctt ccacagcggc ctgaccggcg cggcggccga
     8761 actcgccgcc gggcggctgg acgtgtcctt cgggcgcgtc gccgggctgc ccccggccgt
     8821 acgggcccgc ctggaccacc ggcccgtacg gttcgagccg atggccgtcc tgctggacga
     8881 gggccacccg ctggcgtccc gccccgcagt gcccctgtcc gccctcgcgg gcgagacgct
     8941 ctacgccggg gcgggcaacg cgcagaccgc cgagtggacc gacctcgcca cccgcctctt
     9001 cgcggggcgg gacatcgcga tggcggcgcc gttcccggag atcgagggat cggcggagtt
     9061 catgcgggtg gtgcgcaaac agggctggtc ggtgctggcc agcgtggagt tcatcgacgt
     9121 accgggcatg gcgctgcggc cggtcaccga ccccgtgccg ctctcgccga tatccctggt
     9181 gtggcggcgc gggctgcgcc acgcgggcct ggacgcgctc cgcacggcct gccggagcct
     9241 ggcggcccgg cacggctggc tgcggcggcc ggcgggcccg gactggctgc ccgaagagga
     9301 cgcagccctg atggcgcacg gcggctgacg gccggatctt tgccgtatgg gcaacctgtg
     9361 agccctggaa tccctcctac ggacggcagg aaccatagcc ggactatctg ggggtaccgt
     9421 gcgcaagcgc ccgctgatgg tggcggccct ggccgtgctc gtgctgagcg gtggcctggt
     9481 cgcctgtgac gaaccgcgtg tcgacgcgct gcacgcgagc tgtacgacca aggacctgag
     9541 gtggaaggtc acggtgctga agaagaaagc ccgcagtacg caccgggaag gccggctctc
     9601 ggcggtcaac accggtgcgc gggagtgcgt cttccgcggc ttccccgact tcctcgtacg
     9661 cgtcggcaag gggccggagg cgggcggcgt gggacacggc cgcgcccgcg cggtcagtct
     9721 gcccgccggc tccggcgtcg tggtcgacct gcggtaccgg gacgccgaac gcgggcaccc
     9781 cgccccggcc gactgcctgg tcggcaacgg ttccgccgag gtgacggcgc cccgcgacac
     9841 gcagggcacg ctggtgcggg cgtgggacga gagcggccgg cgggcccggc tggacgtgtg
     9901 cgacaacgtc atccgcatgg agccgccgcg aaaggcctga cgggggcggg ccccacggcc
     9961 agagcccagc ggtcagagcc ccacggccag agccccgcgg tcagggcacc gacagcagcg
    10021 ggtggtacag ccgggtgtca tcgggttcgc ctacggggtg cccgtccacc gctacccagg
    10081 cgtgggcgcg gaacggctcc gtacgcactc ccgtgcacca ctgcggccac cgcccgcgca
    10141 gccggcacaa cagcgcggtc gccacggagc gttgcaggca cccgttgccc gcacagcgca
    10201 cgctgaccgt gacgacggcg tgccgggcgc gcgccgcctc cggggcggtg gcgggaccgg
    10261 cgccgcgccg tacggactcc agcgcgcggc acagcgtgcg cggggagcag cacgtcagga
    10321 ggcgggccgc ggcgacgcag cccagagcgg cgcagcgctc cgcgaaggac aggcgcgcgg
    10381 gggcgccggt ggagacgggg tagctcacga ggtcaccagc ttcgccgact ggagcgactc
    10441 cagcagcgcg acggcgtccg cggccacccg gtcggccgcc gagggatggc ggtagcgcag
    10501 ctcgtcggcg gccgacgcgc aggtgccgcc ggccaggagg tgttccagga cgaacgcgcc
    10561 ggtgttgttc atctgccagt agcggcccgt acgggcgttg agcagcacca tccctccggg
    10621 ggtgcgcaca ctgctgacgt ggggggctag ggcgaacgcc atcgggttca ggctccttcc
    10681 gcggcgggaa cggtggggcg ggcgggggcc tgcgactcct ggagggagcg cagccagtac
    10741 tcggccgcca gggtggggtc gagggggtgc agggtgtggg agcggggctg cagcgaggtg
    10801 agggccgtcc gcagcgcctc gggccggatc aggcccagac cggccaggcg cgagtcgtcg
    10861 cagagcgcgg acagggcccg gcggtggcgg cgcaggcccg cgtagacctc ggcgctgtgc
    10921 tcgcccttgg tgccccgggc ccgcagcgcg tccggcagga ttccgcgcat ggccgcgctg
    10981 agcaggggct tgtacgagcc gaccgcgacc tggtccacga gccgcacggt cagcgcggcc
    11041 tcgatgacgt tgtcgtcgag gaacggggcc tcgaaggtca cgccgtgcgg tgcggtcagg
    11101 gcgtcggcgc cgcgcacgat ctccccggcg cgggcggcgg cccgcagcgt ctcgtgctgg
    11161 cagcgcagcg gcgcgaaggg ctccggggct ccggcggcgg cgtcgcgcac caggcggcgg
    11221 acggtggcca ccgcgtccgg atgcgcccac ggcggcatgg ccgggaccac ctcccagtcg
    11281 gcgccgctgt cgccggaccg cacgccgggc acgatccggt cggcgcagga ctccagccac
    11341 tgcgggtacg ggacgccgcc gaacagggtg cgcagggtgt cgaccagcgt ccagcggccg
    11401 aggcggcggg ccgcgcacgc gcgccgggcg gcggagcgga agtccgtacg ggccagcgag
    11461 ttcagcgcca ccgggcgcgg gctgaacagt tcgtcgccgc cgacgccgac cagatggcgg
    11521 cgcgagccgc gggcggcgac gatcgcggcc tggtgggcca ggcgggcgct ctcccggacc
    11581 acggagagcg ggcctgccgg gtcgccgaga ccgggctgcg gcggggtgta ccaggtgggc
    11641 gcgtcggcgt acgggagcgg gaggtgttcg gccgtgcgga gcagggccgc gccgcggtcg
    11701 ctccacacgg tgtcgtcgtt ggcctcgtcc cggcatcccc aggccgtggt gatcagccgg
    11761 ggggcgtcgc gggcggcgag gaagcacagg ctggtggagt ccatgccgcc ggagaggtcg
    11821 gcgctgaccg ccgggccgcg ggtgcggacc cgaaccgctt cggtcagcgc gtcccgtacg
    11881 gattcggcgg cgtcctccag ccaccggtcc ggctcgggag gccgccacca gcgcaccgtg
    11941 ccgtgccgtc cgtcggcgcc cagggtcagg cagtggccgg gcggtacggc gtgcaccgca
    12001 cgccaggcgg ggcgctgggc gagcgggaac ggcgcgaacg gggcgagcag ccgcagcgcc
    12061 agactctcct cgtcgacgga gccgaggccc ggcgcgccgg tgggcaggcc ggcggcggcc
    12121 gcctcgcggg ccagcgccgc caggtcctgc gggcggctgg ccgcgaccgt gacgccgttg
    12181 atgcccgcgt ggtggagctg ccggatcgtc gacaggctgc cctggcaccg tatgcggggg
    12241 cccatcgcgg ccagcaggaa gaagctgccg ggcagttcgc ggatccggct gtccaggtcg
    12301 tcgaggcggc gcagccggcg cagcagccgg tccagggtcc cggagtcggc ggaggccgta
    12361 ccgagcagca gcagccggtc cgggcccgaa ccggccgcga cggcctcgtc gtcggtccag
    12421 tgccccatga cccaggcgcg tccggagggg tggggcaccg tccgcacggt gggatcgcgt
    12481 ctgagggaca ggcacagcgg accggtcgcg ggatggtcgg ggaagacgac gaagtccacg
    12541 atggcttacc acccctggcg tgcggtgcgg gcgtgtggcg ggaggtcggt tccggtcgga
    12601 tgcgggcagg tggtgcggac gccgtacggg tgggctccgt acggtcgggg gcaggtgcag
    12661 gtgcaggtgc gggtgcgggg gagggcaggt gcgggtgggt gccgggtagg ggtgggcgcc
    12721 gtacctccgg agccggtgcg ccgcggggcg gctgggcccg cggcgccacc ggctgtccgg
    12781 ccgcgtcggt gggggcggcc cctgccgggg cgggcggtgc gcgcccgggc agggaccgcc
    12841 ggactggggg cgtgtgggcg acgtcccgtc aggccggagg gcagcggacc gcgcgggggc
    12901 gcggcacggt ccggtggggc ccgcacggct ccggggtcac caccagccgt gaccgcgccc
    12961 gccgaaggtg tcccagtggt ggccgtggaa gccgagcgtc agctcggcga agtcaccggc
    13021 ctcggccagc tccggcgcct cgtactcgac cgattcgggt tgttcctgga tgtccggcat
    13081 gagtgtgtcg ccttccctca gaagtaccga gccgctcttg aacacaggct gtgctcgcgc
    13141 gattactcag cgcgtccagg gaagatgttg ccagtctcca cggcccctgc cattgcccct
    13201 aacgagtgat gccgggggcg cacggggtgc attggcgtaa cctccggcgg ttgtgcgccg
    13261 ccagcgcgtt ctccgctcac cgcgcgctcc cggacgcggt gagcgcaagg tttcgcgacg
    13321 gtcacgcacc gccacagagg ggaaacgcgc cctccctagc gtcgcggaca cggcggcaac
    13381 cgggagctgg gagacgcgat ggcaggcaca ggaacggcca cgggggaagc ggcggcccgc
    13441 accgccggac ggggagcggg ccgctggatc gaacggtggg acccggagga cgagtccttc
    13501 tggcggcacc acgggcggcg gatcgcccgg cgcaacctcg tgctgtccat cgtctgcgag
    13561 cacatcgggt tctccgtgtg gagcctgtgg tcggtcatgg tcctgttcat ggggccgcag
    13621 tacggaatcg acgcggccgg gaagttcttc ctggtggcgg tgccgacgct ggtgggggcg
    13681 gtgctgcggg tgccgtacac cttcgcggtc gcgcggttcg gcgggcggaa ctggacggtg
    13741 tgcagcgtcg cgctgctgct cgtccccacc gctgccgcgg tgttcgcgct gcggccgggc
    13801 acctcgtaca ccgtcttcct gctggtcgcg gccctggcgg gggtcggcgg cgggaacttc
    13861 gcctcgtcca tgacgaacat caactccttc tacccgctgc ggaagaaggg ctgggcgctc
    13921 ggcctgaacg cgggcggcgg caacatcggc gtccccgtgg tccagctgct cggactgctc
    13981 gtcatcgcca cggccggcgc ggaccgccca cggctcgtcc tcgccgtcta tctgccgctg
    14041 atcgtggtgg ccgccgtcct ggcggcgctc ttcatggaca acctgcggcc ggtgcgcaac
    14101 gacaccgggg cggcccggga agcggcccgc gacccgcaca cctggatcgt ctcgctcctc
    14161 tacgtcggca cgttcgggtc gttcatcggc tacagcttcg ccttcggcct ggtcctgcag
    14221 acccagttcg cgcgcacgcc cctccaggcg gcgtccctga ccttcatcgg gccgctgctc
    14281 gggtccctgg tgcggccggt gggcggccgg ctggcggacc ggtacggcgg cgcccggatc
    14341 accctggcga acttcgcggc gatggcgctg gccacgggcg tggtgatcct ggcgtcggcg
    14401 cggcactcgc tggaggtctt cctcgccgga ttcgtcgtcc tgttcgtgct ctccggcctc
    14461 ggcaacggct ccacgtacaa gatgatcccc ggcatcttcc aggccaaggc gctggcgaag
    14521 ggcctgacgg gcgaggcggt cgcggcccac gggaggcggc tgtccggcgc ggtgatggga
    14581 ctgaccggcg cggtcggcgc gctcggcgga ctgggcgtca acctcgcctt ccgccagtcc
    14641 ttccagtcgg ccggcacggg caccccggcg ttcgtggcct tcctcggctg ctacgcgctg
    14701 tgctccgcgg tgacctgggc cgtatacctg aggcgtacgg cggccaccgt ggccgtacgg
    14761 gaccgggagg cggcggagcc cgcgctcgcg gaggtgtgac gcgcggggcg gcgggcgccc
    14821 gcggcggtcc gtaacagctg ggaaatactg cgggagcgag cccgtcaccg gcggttggca
    14881 ggctcggacc ttcaccggtg cccggtggca ccggagtcag gacaagccag ggacggacca
    14941 tgcacgaggg cgaacaggac gagcgccggg acgacggcgg cacggggcgc ggcgggcggc
    15001 agcacgacgg ccgcggcgcc gcggaccacg gcgccgccgg ccagggggac gggccggggg
    15061 acggcgaccg cggacgcacc gcggcggcca cggacgtacg gcccctggac ggcttcacgg
    15121 tcggggtgac cgccgcccgc cgcgccgagg agctgggcgc cctcctcgaa cggcgcggcg
    15181 cccaggtcgt gcacgccccc gcgctgcgca tcgtgccgct gcccgacgac gcggaactcc
    15241 tcgccgccac caaggacctg atcgaccggg cgccggacgt ggtgatcgcg accaccgcga
    15301 tcggcttccg cggctggatc gaggccgccg agggctgggg gctcggggag gcgctgctcg
    15361 cccggctcgg cgccgtcgaa ctgctggccc gcggcccgaa ggtcaagggc gccatccgcg
    15421 cggccgggct gaccgagaag tggtcgccgg tgtccgagtc gctggcggag gtgctcgacc
    15481 gcctcctgga ggagggcgta cacgggcggc gggtcgtcat ccagctgcac ggcgaaccgc
    15541 tgcccggctt cgtggagtcg ctgcgggcgg gcggcgccga ggtggtcggc gtaccggtct
    15601 accgctggat gccgcccgcc gacatcgggc ccgtcgaccg gctgctggac gcggcggtca
    15661 cccgcggcct ggacgcgatc acgttcacca gcgcgccggc cgccgcctcg ctgctgcgcc
    15721 gcgccgagga gcgcgggatg cgggacgggc tgctgcgcgc gctgcggcac gacgtgctgc
    15781 ccgcctgcgt cgggccggtc accgcgctgc ccctggaagc gcacgaggtg accacgtacc
    15841 agcccgaacg cttccggctc ggcccgctcg tccagctgct gtgccaggaa ctgccgggca
    15901 gggtacggcc gttgacggtg gccgggcggc gggtggagat ccgggggcag gccgtcctgg
    15961 tcgacgggaa cctgcggccc gtacccccgg cgggaatggc gctgctgcgc gcgctggccc
    16021 gcaggcccgg gtgggtggtc tcccgcgccg acctgctgcg cgcgctgccg ggcgcggggc
    16081 gcgacgagca tgcggtggag accgcgatgg cccggctgcg gggggcgctg ggcgcgccca
    16141 agctgatcca gacggtggtc aagcgggggt accggctggc gctcgacccg cggctggggg
    16201 ccaagtacgg cgacgagtga cgtaccccgt cctgcggctg cgcccgggta ccggccgggc
    16261 tggccggacc ttccgggccg ccgctaagtg gggttggtca cccgtatctt ggactggccg
    16321 tgcgggcggg tctcccagtc ctccatgaac cgggcctcca gcccgtgctt gcgggccagc
    16381 gccagcagcg ttccggtgcg gtagtagaag tcctcgcgca gtacctggtg ctcggcgccc
    16441 tcggtgcggt cgaaggtgaa gtcgaagaat ccgccgggtg ccaggatgcg gccgacgtgc
    16501 cggaagctct ggtcgatcac ggacagcggc gagtgcgaga agacgctgtg cgcgtgcacc
    16561 acgtcgaagt gcgcgtccgg caggaagtcg aaggtcaggt cctgggtgat ggtcaggtgc
    16621 ggcagtttgt cctggagttc gtaggtggcc agcgtcttct tggcggatat gaggatgtcc
    16681 ggggagatgt cgatgccgta gtagttgccg gtgtcgaggt gggcgatgaa gcgccagccg
    16741 gcccgcaggt tgccgcagcc gatgtccagc atccgcgtgt ccggccgcag cccgtgttcc
    16801 ttcagatagg tgaactgcat gtcgcccagc gccagccacc gttcgtggct gcggctgccg
    16861 accgcggcct ccgggttgcg gctggtgtcg gaggccatca cggcgcggta gtacgcgacg
    16921 tggtcggggt gcttgaggcg cagccagctg tcccgggcgg tgcgccggag gtagggcgcg
    16981 atgcgcgccg gattgctgac cgcgtaacgg accttgtgcg tcaggctgga gcggttcttg
    17041 agcagggtct tggccgacat ggcccggact atacatcaga ggtatacatg cgatgtatac
    17101 agagcgggcg gcgcggtacg cggcggtgcc gagggttacg gcccggggcc ctgccgggca
    17161 ctctgatagg gcagaagctg tctcctaagg agtgacgggc acatggcggc gccttttgac
    17221 ctgcggttcg actgcgggcg gatctgcctg gacctgatgg ccacgaccgg ccggaccgcc
    17281 gaacgcctgg ccggccccga acatctggcg gcctggctgg tgggctcggg cgtcgtcccc
    17341 ggcagcaccc agctcggcgc cgtcgaccgc ggctgggtcg tacgcttccg gatgctgcgc
    17401 gaactgctgc gccgcgtcat ccacgacgaa ctgcgcggcc gggccgccga cggcgacctg
    17461 cgcctgctca acgcggcggc ggccgcggcc cccgtaccgc ccgcccgcgc cgtacggacc
    17521 gacgacggcg gcctggtccg ggcgttcgcc gggccgcccg actgcgccgg actgctcgcc
    17581 gcggtggcac gggacgcgat agcgatgctg accgacgcgg tgacgcgcgg ccagctgcgg
    17641 cagtgcgagg gcgagagctg ctcgttggtg tacctggaca cctcgcgcgg acggcggcgc
    17701 cggtggtgct ccagcgaggt gtgcgggaac cgggagcggg tggcgcgcca ccggcggcgg
    17761 gccacccgcc gggagctttc gggtcagccg cctgtcgtac gcccggccgt gcgcacggtg
    17821 ccgacgaaga cgtagtcggc ccggtagggc accgcggcct ccgggtgcgc ggccgggtcg
    17881 caggcgccgc cgggggcgac gccgcccgcc gtgttcagcc ggaggatctc gccgacctgg
    17941 ccgagccggc cgtccggcgg ccccgaccgg cgggcgtcca gggcgagttc ggggatgttg
    18001 cccgcgccgt tcggggtctt cgagcggacc gtgccggtga cggcggagcg gtccggtgcc
    18061 acccatacgg gcggcccctt ggggccgggc gcggcgaaga agtgtgcgat gccgccttcg
    18121 aggagagcgc gtacgtcgcg ctgcgtataa gcgtaactcc cgtcgccctg ccgggtgcag
    18181 gcgtagatct gcgcgccgtg gaccaccgga gcccgcacgc tgtgccgcag ggcccggtcc
    18241 gcgtcgacag gttccgccaa tgcgtggagc cgtccgcgta tcgcgccgtg cgggaatcgc
    18301 tccgtaagga gattgaaaga gaaactattc ggctgtctcc gcagagcgtc caggacacgt
    18361 cggccggaga tctcgaccgt gccgctcacc gaggtcttcc cggcggaaag ccgccccgtg
    18421 aacagaggaa tgcgtacggg ccctccggcg cctttccccg cttcccggag gacggccgcg
    18481 acgggcgtgg cgacgccccg gaaggacagc gcgaaggaga gccggccgcc ccgcagacgg
    18541 aggaaggcca gcccccgccc gtcccggtcg cccgtcccgg acgcctcgtt ctccgcgctc
    18601 agactgctca cgaaggagac cgctccgccg cccccggcct gcgctgtctg cgctgcgtgc
    18661 gcgggcggcg ccatgagcgc cacagcgacg gcggccgcgg cgcaggcagc ggcgatggcc
    18721 ctgtcacgac tcacggtgta cctccctgcc accggagccc ggccttcgcg ccgggctcgt
    18781 cgggctgctg tacggggcgc ccgccgcggc cgttcaccgg gaaagggggg cagcgtcacg
    18841 gcggccgggc cgaacgcccg gaaggagaaa accgtgacgc ccgcgcgggc gcaccgggag
    18901 gcacgcgcac cggcgcgcgg gaaacgcccg cccacccgca cgggtaaccc cgccaccgcg
    18961 ccgggaattc accccgcggg tgctgagccg cggcgcaccc ggacccgtac tgctggctga
    19021 aggggcgtga atgggcccgg aattcgagac gagggggcgg acatgcgcga gcccggacgc
    19081 ggacggcaga ccgggaccac cggcggtacg gacggtgacg gcagcgacac cggcgacgcg
    19141 cgagagcgct gagacccgtg cgcagcgaat gtccgatccg tgctatcgac ccgggagttg
    19201 gcgtgcgcga ggatgccgtc gtggcagaca gtacgtcgcc ggacgaggag ctgatgcggg
    19261 ccctctacga ggagcacgcg ggcccgctgc tcgccttcgt gctgcgcctg gtcgccgggg
    19321 accggcaccg ggcggaggac gtggtgcagg agaccctgct gcgggcctgg cgcaacgccg
    19381 gccagttgca gcgcgcgacc ggctccgtcc gcccctggct ggtcaccgtc gcccggcgga
    19441 tcgtcatcga cagccaccgc agccgtcagg cgcggcccca ggaggtcgac gccgccccct
    19501 tggaatcgat gccggccgcc gacgagatcg accgggccct gcgcctgatg acgatcaccg
    19561 aagcgctcgg cgacctcagt gcggcccacc gagaggcgtt gattgagacc tacttcaagg
    19621 ggcgtacggt cagcgaggcg gccgaagtgc tccgggtgcc ggccggaacc gtccggtccc
    19681 gggtcttcta cgccctgcgc tccctgaagc tctcgcttga agaacgagga gtgacggcgt
    19741 gatgcggccc acggagcccg tagaacacac cgacgtcggc gcctacgcgc tgggcgtcct
    19801 ggacgccgcc gaggcggcac gcttcgagga gcacctggcc ggctgcgacc ggtgcgccgc
    19861 cgaactcgac gacctgatgg gtctgccgcc cctgctcgcc gacgccaggg aggcggcacc
    19921 cgacccggag gcggtcaccc cggtccccgg gccgggcctg ctggacggcc tcctggccga
    19981 ggtcggcgcg gtgcgccgca cccgccgcag gcgccgcctg tacctggtgg ccgccgccgc
    20041 ggtgctggtc gccggcggcc cgctcaccac gtacgcgctg accgcggggg acaccgacga
    20101 gaccccggaa cacctggcga gctacgcccg cacgatgtac gagcacggcg agaaggccgg
    20161 cacggtcgac ccggtgacca aggtcgccgc cagcgtctcc atggaacgca agccctgggg
    20221 cacccacgtc gccctcaagc tgggcaacgt caagggcccg ctcacctgcg atctggtcgc
    20281 gatcggcaag aacggcgcgg agcagaccgt gacgacctgg gcggtgcccg cgggcggcta
    20341 cggcctcaag gacggcgcca ccaagtggaa caaggaaccc ctctacacgc acggcggcgc
    20401 ggccatgaac cgttccacca tcgaccgctt cgaggtccgc acgctcgacg gcaggcggct
    20461 ggccgagatc aaggtctgac cggacggcgg cggggcccgg cgggaagcgc ctccggtgaa
    20521 gcctcggcgc tcccgatgat tccgcggcgc tcccggtgaa gcctccggcg ccccggtgaa
    20581 cccttcggcg cccccctggt gaagccttca gtgccgccag atgaagcctc cagcgccgcc
    20641 agatgaagag gaaccgctga ttccgcacaa tccgcccgct catgttgccc ggtttggtcc
    20701 cacccggtgg tgatttcgtc cttcgggtca ggtgcgcccg gtgcctggtt cgcgtacggt
    20761 tgacggctgc cctacgcaca gaagaagggg gcctgggtgg ccgcgcagaa tgccacgcac
    20821 gcgccggact ccgtcgacga cgcacagccg gacagcacac gcgaacgcga gatctcatcc
    20881 gaacaggagc atctcgaccg tgtctaccag cgtctagagg agaagatcca cgaggccgag
    20941 ttcctcatgg acgacgccgc caaacgcggc caggtcggca cgcccggcgc cctcgccgag
    21001 cgggacgccc aggtcttcca ggccggcgcc cacctgaacc ggctcaactc cgagtacgag
    21061 gacttcctct tcggccgcat cgacctgctg ccgggcaagg acggcaagaa gggcccggac
    21121 ggcgcgtaca cctccgtcga ccccgccgac ggcgccgtca ccgacggccg cgccgagatc
    21181 gccgagaccc tgcacatcgg ccgcctcggc gtcctggacg ccgactacag cccgctggtc
    21241 atcgactggc gcgcgcccgc cgccgccccc ttctaccggg ccaccccggt cgcgccgggc
    21301 cgcgtcgtac gccgccgggt catccgctcc aagggccgcc gcgtcctggg cgtcgaggac
    21361 gacctgatgc gcccggagat cagcgcgaca ctcgacggcg aggaactgcc cgcggtcggc
    21421 gacggcgcgc tgatggccgc cctgggccgg gcccgcagcc actcgatgcg cgacatcgtc
    21481 gcctccatcc aggccgagca ggacatggtc atccgggccc ccgccgcctc cgtcacggag
    21541 gtcgagggcg gccccggcac cggcaagacc gcggtggcgc tgcaccgcgc cgcctacctc
    21601 ctctaccagg accgccgccg ctacgcgggc ggcatcctca tcgtctcccc gacgccgctg
    21661 ctcgtcgcgt acaccgaagg cgtcctgccg tccctcggcg aggagggcca ggtcgccatc
    21721 cgcgctttgg ggtctcttgt ggacggtgca gaggccaccg cttacgactc cccggccgtc
    21781 gcccggatca agggctccag ccgcatgcag aaactgctgc gcaaggcggc ccgcggagcc
    21841 ctggaaatgg ccgcggcggc gcccgccggg gccgccgccc ccgcgcccgc cgacggccag
    21901 ctcgccttcg gcgaggacga cgaggagacg gcggccccca ccggaccgcc ggaccgcctg
    21961 cgggtggtcg tcttcggcgc ccgcgtcgaa ctggacgccc gcgacctgca ccgcgtccgg
    22021 cagtccgccc tcggcggcac cgcaccggtc aacctgctgc gcccgcgcgc ccgccgcctc
    22081 gtcctggacg ccctgtggtc ccggtccggc tccgccaagc gctacacgga tcccgaactg
    22141 gccgccgagg cgcgccaggc gttcgacgag gacatcacca ccgagccgga cttccaggac
    22201 ttcctcgacg cctggtggcc ggagctgacg ccgcgcggcg tgctggccgc gatggccgac
    22261 gagcgacggc tgggccgctg ggcgcgccgc gtgctcaacc agcgcgaagt gcgcagactg
    22321 gcccgctccc tgagccgtct ggacgccaag gggcagggcc cgctgtcggt ccacgacgtg
    22381 gcgctgctgg acgagctgca gctgatcctc ggcgcgccgc cccggcccgc caggccccgc
    22441 gaggccgatc cgctggacca gctcaccggt ctggaggagc tgagcaccta cggcgagcgc
    22501 atgtccggcg gcggccgcgg cagacgcgac cgcctggag
//
