LOCUS       NZ_MPOH02000048        16523 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces phaeoluteigriseus strain DSM 41896 Scaffold_48, whole
            genome shotgun sequence.
ACCESSION   NZ_MPOH02000048
VERSION     NZ_MPOH02000048.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 16523)
  AUTHORS   Salih,T.S., Algora Gallardo,L., Melo Santos,T., Filgueira
            Martinez,S. and Herron,P.R.
  TITLE     Draft genome sequence of Streptomyces phaeoluteigriseus type strain
            DSM41896
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16523)
  AUTHORS   Salih,T.S., Algora Gallardo,L., Melo Santos,T., Filgueira
            Martinez,S. and Herron,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2017) Strathclyde Institute of Pharmacy and
            Biomedical Sciences, University of Strathclyde, 161 Cathedral
            Street, Glasgow G40RE, United Kingdom
REFERENCE   3  (bases 1 to 16523)
  AUTHORS   Schniete,J.K., Salih,T., Algora Gallardo,L., Martinez Fernandez,S.
            and Herron,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2016) Strathclyde Institute for Pharmacy and
            Biomedical Sciences, University of Strathclyde, 161 Cathedral
            Street, Glasgow G40RE, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-JAN-2017
            Assembly Method                   :: SPAdes v. 3.9; MeDuSa v. 1.6
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: IonTorrent
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001896135.2-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:12:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,918
            CDSs (total)                      :: 7,837
            Genes (coding)                    :: 6,622
            CDSs (with protein)               :: 6,622
            Genes (RNA)                       :: 81
            rRNAs                             :: 3 (5S)
            complete rRNAs                    :: 3 (5S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 1,215
            CDSs (without protein)            :: 1,215
            Pseudo Genes (ambiguous residues) :: 0 of 1,215
            Pseudo Genes (frameshifted)       :: 907 of 1,215
            Pseudo Genes (incomplete)         :: 407 of 1,215
            Pseudo Genes (internal stop)      :: 30 of 1,215
            Pseudo Genes (multiple problems)  :: 120 of 1,215
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:00:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 16523
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MPOH02000048.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..16523
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            complement(<1..396)
                     /locus_tag="BM536_RS43620"
                     /old_locus_tag="BM536_037760"
                     /pseudo=""
     CDS             complement(<1..396)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BM536_RS43620"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BM536_037760"
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIGANWAWTVLMAVIALSRDPFTLTAAYAAMWFVGPLWNVALGSY
                     QLSITPDPLRGRVLAATSTLSNGALPVGSLLGGLLLDSAGARTAALALAGWMVVIAGAA
                     SLARSVRAAPGPPARCPPAPGPAAAPPP"
     source          1..16523
                     /culture_collection="DSM:41896"
                     /db_xref="taxon:114686"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces phaeoluteigriseus"
                     /strain="DSM 41896"
                     /submitter_seqid="Scaffold_48"
                     /type_material="type strain of Streptomyces
                     phaeoluteigriseus"
     cand_cluster    1..16523
                     /SMILES="NC([*])C(=O)NC([*])C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)O
                     "
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16523
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[4237:13952](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4238..13952
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(393..1319)
                     /locus_tag="BM536_RS37845"
                     /old_locus_tag="BM536_037765"
     CDS             complement(393..1319)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="BM536_RS37845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_037765"
                     /product="MFS transporter"
                     /protein_id="WP_245873999.1"
                     /transl_table=11
                     /translation="MTSPDTRASADPRPPDPPDAATDDPVVPLHRNRDFLLLWGGSAVS
                     QLGSTATTIAYPLLVLAITGSPFAAGLAGFVTLLPALLLPLPAGALVDRWPRRRLMIWC
                     DALRALGAATIAVASALDVLGLPLVLAVGFAEGALTVFHGLAAHAAVPNVVPPSQLSLA
                     LSRNEARGRAAVMLGTPLGGMLFGLGRAVPFLADALTYLVSLTGLLFIRKEFEAKRSAR
                     TGSMREQVHEGLRWLWRQPFLRTTTLLVAGSNLMFRALFLVAIVLATDIGASSTGVGLM
                     VGFAGAGGVLGSLAAPWFARRVGLAPW"
     gene            complement(1353..1571)
                     /locus_tag="BM536_RS37850"
                     /old_locus_tag="BM536_037770"
     CDS             complement(1353..1571)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191144.1"
                     /locus_tag="BM536_RS37850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_037770"
                     /product="MbtH family protein"
                     /protein_id="WP_073497709.1"
                     /transl_table=11
                     /translation="MAEEDIDERTYRVVLNDEEQYSVWLADRELPLGWHAEGTEGTRAE
                     CLAHIGTVWTDMRPLSLRRQMGQAARV"
     gene            1763..2794
                     /locus_tag="BM536_RS37855"
                     /old_locus_tag="BM536_037775"
     CDS             1763..2794
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (24-320). E-value: 4.3e-50. Score:
                     162.9. Matches aSDomain:
                     nrpspksdomains_BM536_RS37855_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580242.1"
                     /locus_tag="BM536_RS37855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_037775"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_073497707.1"
                     /sec_met_domain="TauD (E-value: 7.9e-51, bitscore: 162.9,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTANPSVRTAPADRAQERDASSALPLTLSAESPGTPLSEYLSAAR
                     PLVRGRLLEHGAVLLRGFDVGGVDGFEAAVRAVSGAPLPYAERSSPRSTIKGQVYTSTD
                     YPPDEEIFLHNENSYQADWPLTLFFHCVQPPDTLGATPLADTRRVYRAIDPSVREEFAA
                     RGWMVVRNFSDGFGVPWQQAFGTDDRGEVEAYCARNGVETEWTADGLRTRARRRAVHRH
                     PVTGETVWFNHLTFFHVTTLAEEVCGALREMYDDARLPTNTYYGDGRPIPDEVVAHLRS
                     CYRAEQRRFDWRRDDVLLVDNMLSAHAREPFTGPRRIAVAMAEPFSAAARSAAFAEVTD
                     VRR"
     aSDomain        1835..2722
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS37855_TauD.1"
                     /evalue="4.30E-50"
                     /label="BM536_RS37855_TauD.1"
                     /locus_tag="BM536_RS37855"
                     /protein_end="320"
                     /protein_start="24"
                     /score="162.9"
                     /tool="antismash"
                     /translation="PLTLSAESPGTPLSEYLSAARPLVRGRLLEHGAVLLRGFDVGGVD
                     GFEAAVRAVSGAPLPYAERSSPRSTIKGQVYTSTDYPPDEEIFLHNENSYQADWPLTLF
                     FHCVQPPDTLGATPLADTRRVYRAIDPSVREEFAARGWMVVRNFSDGFGVPWQQAFGTD
                     DRGEVEAYCARNGVETEWTADGLRTRARRRAVHRHPVTGETVWFNHLTFFHVTTLAEEV
                     CGALREMYDDARLPTNTYYGDGRPIPDEVVAHLRSCYRAEQRRFDWRRDDVLLVDNMLS
                     AHAREPFTGPRRIAV"
     gene            2781..4256
                     /locus_tag="BM536_RS43625"
     CDS             2781..4256
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (7-308). E-value:
                     7.8e-97. Score: 315.8. Matches aSDomain:
                     nrpspksdomains_BM536_RS43625_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="BM536_RS43625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_245874000.1"
                     /sec_met_domain="Condensation (E-value: 1.4e-66, bitscore:
                     214.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADDSGLPLSFAQEQLWFLDQLRSGASTEYLMCEAFRIRGPLDT
                     RVLEAAFTEISARHEVLRTRYGTATGAGAQFVDEPGPVRLARVDLTGTAPADREARVRE
                     LHAAELRTPIDLRDRAPWRLTLVRFAEEDAALLVTVHHIAFDGWSWGVLARELHELCTA
                     FAAGRPSQLEPVPVQYADFAQWQRDTWAAAPERAGRRRGYWRERLAGLEPLELPADRRR
                     PAQWDPAGDSVAFTVPAELAGRLAVVGRDAGATPFMVHLAAFQLLLARWSGRTDVAVGV
                     SVSDRNEVELEPLVGLFLNTVVMRTDLSGRCSFLDLLARVRETTLDAYEHQDVPFGWVV
                     ADLAPERDPSRNPVFQVGFALHNAERRPLRLPGLDVAKVEPATDHSAFDLSLHLSELPD
                     GSMAARLIFPTALFDRARIERMAASLLRLLTSIAEHPDLPAHALETVPVTELAAFERWN
                     RTGTERPRQSLAELFFAQALATPEAVAWCPASG"
     aSDomain        2802..3704
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43625_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.80E-97"
                     /label="BM536_RS43625_Condensation_LCL.1"
                     /locus_tag="BM536_RS43625"
                     /protein_end="308"
                     /protein_start="7"
                     /score="315.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAFDG"
                     /tool="antismash"
                     /translation="LPLSFAQEQLWFLDQLRSGASTEYLMCEAFRIRGPLDTRVLEAAF
                     TEISARHEVLRTRYGTATGAGAQFVDEPGPVRLARVDLTGTAPADREARVRELHAAELR
                     TPIDLRDRAPWRLTLVRFAEEDAALLVTVHHIAFDGWSWGVLARELHELCTAFAAGRPS
                     QLEPVPVQYADFAQWQRDTWAAAPERAGRRRGYWRERLAGLEPLELPADRRRPAQWDPA
                     GDSVAFTVPAELAGRLAVVGRDAGATPFMVHLAAFQLLLARWSGRTDVAVGVSVSDRNE
                     VELEPLVGLFLNTVVMRTDL"
     aSModule        2802..5929
                     /complete
                     /domains="nrpspksdomains_BM536_RS43625_Condensation_LCL.1"
                     /domains="nrpspksdomains_BM536_RS37860_AMP-binding.1"
                     /domains="nrpspksdomains_BM536_RS37860_PCP.1"
                     /locus_tags="BM536_RS37860"
                     /locus_tags="BM536_RS43625"
                     /monomer_pairings="X -> X"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2811..2843
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0001"
                     /evalue="5.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BM536_RS43625"
                     /protein_end="21"
                     /protein_start="10"
                     /score="9.4"
                     /tool="antismash"
                     /translation="SFAQEQLWFLD"
     CDS_motif       2871..2978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0002"
                     /evalue="6.20E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="BM536_RS43625"
                     /protein_end="66"
                     /protein_start="30"
                     /score="47.6"
                     /tool="antismash"
                     /translation="YLMCEAFRIRGPLDTRVLEAAFTEISARHEVLRTRY"
     CDS_motif       3198..3260
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0003"
                     /evalue="4.80E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="BM536_RS43625"
                     /protein_end="160"
                     /protein_start="139"
                     /score="31.9"
                     /tool="antismash"
                     /translation="VHHIAFDGWSWGVLARELHEL"
     CDS_motif       3312..3344
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0004"
                     /evalue="3.30E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="BM536_RS43625"
                     /protein_end="188"
                     /protein_start="177"
                     /score="13.4"
                     /tool="antismash"
                     /translation="QYADFAQWQRD"
     CDS_motif       3537..3596
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0005"
                     /evalue="3.00E-03"
                     /label="Cy4"
                     /locus_tag="BM536_RS43625"
                     /protein_end="272"
                     /protein_start="252"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GATPFMVHLAAFQLLLARWS"
     CDS_motif       3606..3695
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0006"
                     /evalue="5.30E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="BM536_RS43625"
                     /protein_end="305"
                     /protein_start="275"
                     /score="34.9"
                     /tool="antismash"
                     /translation="DVAVGVSVSDRNEVELEPLVGLFLNTVVMR"
     CDS_motif       3744..3863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43625_0007"
                     /evalue="2.40E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BM536_RS43625"
                     /protein_end="361"
                     /protein_start="321"
                     /score="71.4"
                     /tool="antismash"
                     /translation="RETTLDAYEHQDVPFGWVVADLAPERDPSRNPVFQVGFAL"
     gene            4238..8587
                     /locus_tag="BM536_RS37860"
                     /old_locus_tag="BM536_037780"
     CDS             4238..8587
                     /NRPS_PKS="Domain: AMP-binding (4-385). E-value: 4.7e-103.
                     Score: 336.9. Matches aSDomain:
                     nrpspksdomains_BM536_RS37860_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (495-564). E-value: 9.2e-27. Score:
                     85.1. Matches aSDomain: nrpspksdomains_BM536_RS37860_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (590-887). E-value:
                     6.7e-108. Score: 352.1. Matches aSDomain:
                     nrpspksdomains_BM536_RS37860_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1060-1413). E-value:
                     6.5e-83. Score: 270.5. Matches aSDomain:
                     nrpspksdomains_BM536_RS37860_AMP-binding.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="BM536_RS37860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_037780"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_281258624.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-116, bitscore:
                     377.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8e-18, bitscore:
                     54.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.7e-75, bitscore:
                     242.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGERVTGYAELADRVRRLAGLLRSRGVGPESAVGVALHRGTDLV
                     ATVLAVLTAGGVYVPLAPEHPAERLAHLVTDAEVTLLVTEEALSGRLPAHPNTLVLDAV
                     RPGEDEEAPLLEPAGGVGTQAAYVMYTSGSTGRPKGVVVPEAAIRNRVLWSVERFGLGP
                     GDRVLQRTTIGFDAAVWEFLSPLVCGAAVVTGPRDAHRDPAVMVRAVVDHRVTVLQGVP
                     SMLRLLLEEPALADCAALRLLCSAGEPLPAELADRLRRALDAEVVNTYGPTECAVDSTA
                     WHFDPDEPGDLVPIGLPLPNVRTYVVDAEGLPVPVGVTGELYVGGIGLARGYAGRGDLT
                     ADRFVPDPDATVPGARRYRTGDLVRRRADGALEYVGRVDDQVKIGGVRIEPGEIEVLLA
                     AHPSVAAAAVAVHRSAAGDARLTAYAVPAAGERIDPEALRVHLAAALPEAMLPSAFVGL
                     AELPLTPNGKVDRRRLPAATEPDRPAAEARQAPRTAAEETVAELMAEILGVERVGAHDD
                     FFLLGGHSLLAIRLVLRLRRAFGSELTVGELFQARTVAALAARVTEAGAGSRTALDGDP
                     DADPDAVRPAGRDRPLPLSFGQQRMWFLDQLEPGTYEYVVPLALRLTGPLETGALRHAL
                     DALSERHEVLRTRYRSEGGEPVQVVDPAGPVDFTLTDLTGAPDAEHRARALVDGLARQP
                     FDLEHGHPLRASLIRTGPEDHLLVLTLHHIAFDAWSTNVYLRDLDLSYRAFAAGEPSPH
                     APQPVRYADFAVWQREQQRAGRLDHQLAYWRDRLDGLTPVELPTDRVRSAVRDARGDNI
                     VVEVPPEVARAVAELAGRHGATPFMVMLAAFQVLLRRWTGRDDLAVGTPVAGRTRQETE
                     DMVGFFTNNLVIRSDLGGNPVFGELLDQVRGTVLDAFAHQDVPFEHLVDALQPERDLSR
                     NPLFQIMFEHQHLAGVPDRLGAVSVEPVRAGLETAKFDLTVTVKERGGRMYCWFEYATA
                     LFDRETVERMAGHYLTLIAGVTAAPGARIGDLDMLTGDERHRALTAWADPGSERTTVLD
                     PAEEHGLCVPELFARQVRRAPDAIAVVFGDQQVSYAELDARSARFAAHLRSLGVTAETI
                     VGSCLERGVEAVVVLLAVLRAGGVYVPFDPGHPAERLQLMLADAGPELVVTTRAFADRL
                     TGAHRVVLADADADADIDADARDEPGTAPDGPAPVPTRPHNLAYVIYTSGSTGRPKGVM
                     IEHRAYAHHCRVIADAYGIAPGERVALLSALTFDVAMDQIAATLVAGATVVVADPVFWT
                     PDELPARLAEHGVTVLEITPSYYRAVLESPHLSLLDSLKLMNVGSDVVTGLDARRWTET
                     GLPARFLCNYGPTEATVTCLLHPVPETPAEGDAAGALPLGRPVPGTRAYILDADLRPVP
                     VGVPGELYLGASGWPAATTGDRTSPRSGSSPTPSPPSPAGASTAPAT"
     aSDomain        4250..5392
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS37860_AMP-binding.1"
                     /evalue="4.70E-103"
                     /label="BM536_RS37860_AMP-binding.1"
                     /locus_tag="BM536_RS37860"
                     /protein_end="385"
                     /protein_start="4"
                     /score="336.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RVTGYAELADRVRRLAGLLRSRGVGPESAVGVALHRGTDLVATVL
                     AVLTAGGVYVPLAPEHPAERLAHLVTDAEVTLLVTEEALSGRLPAHPNTLVLDAVRPGE
                     DEEAPLLEPAGGVGTQAAYVMYTSGSTGRPKGVVVPEAAIRNRVLWSVERFGLGPGDRV
                     LQRTTIGFDAAVWEFLSPLVCGAAVVTGPRDAHRDPAVMVRAVVDHRVTVLQGVPSMLR
                     LLLEEPALADCAALRLLCSAGEPLPAELADRLRRALDAEVVNTYGPTECAVDSTAWHFD
                     PDEPGDLVPIGLPLPNVRTYVVDAEGLPVPVGVTGELYVGGIGLARGYAGRGDLTADRF
                     VPDPDATVPGARRYRTGDLVRRRADGALEYVGRVDDQVKIG"
     CDS_motif       4382..4420
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0001"
                     /evalue="1.80E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="BM536_RS37860"
                     /protein_end="61"
                     /protein_start="48"
                     /score="11.9"
                     /tool="antismash"
                     /translation="LAVLTAGGVYVPL"
     CDS_motif       4613..4669
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0002"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BM536_RS37860"
                     /protein_end="144"
                     /protein_start="125"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGRPKGVVVP"
     CDS_motif       5045..5068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0003"
                     /evalue="4.50E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="BM536_RS37860"
                     /protein_end="277"
                     /protein_start="269"
                     /score="6.9"
                     /tool="antismash"
                     /translation="YGPTECAV"
     CDS_motif       5180..5269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0004"
                     /evalue="1.80E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="BM536_RS37860"
                     /protein_end="344"
                     /protein_start="314"
                     /score="45.8"
                     /tool="antismash"
                     /translation="PVGVTGELYVGGIGLARGYAGRGDLTADRF"
     CDS_motif       5357..5422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0005"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BM536_RS37860"
                     /protein_end="395"
                     /protein_start="373"
                     /score="33.6"
                     /tool="antismash"
                     /translation="YVGRVDDQVKIGGVRIEPGEIE"
     aSDomain        5723..5929
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS37860_PCP.1"
                     /evalue="9.20E-27"
                     /label="BM536_RS37860_PCP.1"
                     /locus_tag="BM536_RS37860"
                     /protein_end="564"
                     /protein_start="495"
                     /score="85.1"
                     /tool="antismash"
                     /translation="EETVAELMAEILGVERVGAHDDFFLLGGHSLLAIRLVLRLRRAFG
                     SELTVGELFQARTVAALAARVTEA"
     aSDomain        6008..6898
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS37860_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.70E-108"
                     /label="BM536_RS37860_Condensation_LCL.1"
                     /locus_tag="BM536_RS37860"
                     /protein_end="887"
                     /protein_start="590"
                     /score="352.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAFDA"
                     /tool="antismash"
                     /translation="PLPLSFGQQRMWFLDQLEPGTYEYVVPLALRLTGPLETGALRHAL
                     DALSERHEVLRTRYRSEGGEPVQVVDPAGPVDFTLTDLTGAPDAEHRARALVDGLARQP
                     FDLEHGHPLRASLIRTGPEDHLLVLTLHHIAFDAWSTNVYLRDLDLSYRAFAAGEPSPH
                     APQPVRYADFAVWQREQQRAGRLDHQLAYWRDRLDGLTPVELPTDRVRSAVRDARGDNI
                     VVEVPPEVARAVAELAGRHGATPFMVMLAAFQVLLRRWTGRDDLAVGTPVAGRTRQETE
                     DMVGFFTNNLVIRSDL"
     aSModule        6008..9189
                     /complete
                     /domains="nrpspksdomains_BM536_RS37860_Condensation_LCL.1"
                     /domains="nrpspksdomains_BM536_RS37860_AMP-binding.2"
                     /domains="nrpspksdomains_BM536_RS43630_PCP.1"
                     /locus_tags="BM536_RS37860"
                     /locus_tags="BM536_RS43630"
                     /monomer_pairings="X -> X"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6077..6187
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0006"
                     /evalue="2.70E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="BM536_RS37860"
                     /protein_end="650"
                     /protein_start="613"
                     /score="48.7"
                     /tool="antismash"
                     /translation="YVVPLALRLTGPLETGALRHALDALSERHEVLRTRYR"
     CDS_motif       6398..6451
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0007"
                     /evalue="7.20E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="BM536_RS37860"
                     /protein_end="738"
                     /protein_start="720"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LHHIAFDAWSTNVYLRDL"
     CDS_motif       6515..6547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0008"
                     /evalue="1.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="BM536_RS37860"
                     /protein_end="770"
                     /protein_start="759"
                     /score="14.7"
                     /tool="antismash"
                     /translation="YADFAVWQREQ"
     CDS_motif       6800..6889
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0009"
                     /evalue="2.30E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="BM536_RS37860"
                     /protein_end="884"
                     /protein_start="854"
                     /score="48.9"
                     /tool="antismash"
                     /translation="DLAVGTPVAGRTRQETEDMVGFFTNNLVIR"
     CDS_motif       6938..7054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0010"
                     /evalue="9.00E-26"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BM536_RS37860"
                     /protein_end="939"
                     /protein_start="900"
                     /score="82.4"
                     /tool="antismash"
                     /translation="RGTVLDAFAHQDVPFEHLVDALQPERDLSRNPLFQIMFE"
     aSDomain        7418..8476
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS37860_AMP-binding.2"
                     /evalue="6.50E-83"
                     /label="BM536_RS37860_AMP-binding.2"
                     /locus_tag="BM536_RS37860"
                     /protein_end="1413"
                     /protein_start="1060"
                     /score="270.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FARQVRRAPDAIAVVFGDQQVSYAELDARSARFAAHLRSLGVTAE
                     TIVGSCLERGVEAVVVLLAVLRAGGVYVPFDPGHPAERLQLMLADAGPELVVTTRAFAD
                     RLTGAHRVVLADADADADIDADARDEPGTAPDGPAPVPTRPHNLAYVIYTSGSTGRPKG
                     VMIEHRAYAHHCRVIADAYGIAPGERVALLSALTFDVAMDQIAATLVAGATVVVADPVF
                     WTPDELPARLAEHGVTVLEITPSYYRAVLESPHLSLLDSLKLMNVGSDVVTGLDARRWT
                     ETGLPARFLCNYGPTEATVTCLLHPVPETPAEGDAAGALPLGRPVPGTRAYILDADLRP
                     VPVGVPGELYLGA"
     CDS_motif       7604..7645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0011"
                     /evalue="2.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="BM536_RS37860"
                     /protein_end="1136"
                     /protein_start="1122"
                     /score="14.7"
                     /tool="antismash"
                     /translation="LAVLRAGGVYVPFD"
     CDS_motif       7862..7921
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0012"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="BM536_RS37860"
                     /protein_end="1228"
                     /protein_start="1208"
                     /score="36.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVMIEH"
     CDS_motif       8291..8323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS37860_0013"
                     /evalue="2.40E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="BM536_RS37860"
                     /protein_end="1362"
                     /protein_start="1351"
                     /score="10.5"
                     /tool="antismash"
                     /translation="NYGPTEATVTC"
     misc_feature    complement(8630..8645)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            8719..9264
                     /locus_tag="BM536_RS43630"
     CDS             8719..9264
                     /NRPS_PKS="Domain: PCP (89-157). E-value: 8.7e-28. Score:
                     88.3. Matches aSDomain: nrpspksdomains_BM536_RS43630_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024591.4"
                     /locus_tag="BM536_RS43630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_245874002.1"
                     /sec_met_domain="PP-binding (E-value: 1.5e-20, bitscore:
                     63.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTAPRTAPGERRLAAYLVARPDSPMPGVAELRGHLGALLPEYMI
                     PSVWVPLDAFPLTASKKIDRNALPDASAALAGGAREHLAPRDPAEQAVAAIWSEVLGLE
                     RIGAQDDFFALGGHSLLATRVLARLRETFAVELPLRLLFEATTVARLSEAVSEAVEADV
                     AALSDQEVAGLLAEEGLR"
     aSDomain        8986..9189
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43630_PCP.1"
                     /evalue="8.70E-28"
                     /label="BM536_RS43630_PCP.1"
                     /locus_tag="BM536_RS43630"
                     /protein_end="157"
                     /protein_start="89"
                     /score="88.3"
                     /tool="antismash"
                     /translation="EQAVAAIWSEVLGLERIGAQDDFFALGGHSLLATRVLARLRETFA
                     VELPLRLLFEATTVARLSEAVSE"
     CDS_motif       9049..9078
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43630_0001"
                     /evalue="3.30E-03"
                     /label="PCP_mC"
                     /locus_tag="BM536_RS43630"
                     /protein_end="120"
                     /protein_start="110"
                     /score="10.8"
                     /tool="antismash"
                     /translation="DFFALGGHSL"
     gene            9261..>9929
                     /locus_tag="BM536_RS44130"
                     /pseudo=""
     CDS             9261..>9929
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (38-221). E-value:
                     9.2e-59. Score: 190.8. Matches aSDomain:
                     nrpspksdomains_BM536_RS44130_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="BM536_RS44130"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 1.1e-39, bitscore:
                     125.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTRDRAQLRQELLRRRLAGRAAPAPAEGIGRAPRGGPLPLSFA
                     QRRLWILDRLQPGGTEYLMTVALRLRGPLDRAALRTALDGILHRHEVLRTRYPVVDGEP
                     VQIVDEPGSVPLDEEDLGALDRTAADARIAALATGARRPVDLAEGPVFSTVLARLAPQE
                     HALLLTVHHIACDGRSEDVLVRELAERYEDAVAGRPTRSPEPPVQYADFALWQRERLSG
                     A"
     aSDomain        9375..9923
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS44130_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.20E-59"
                     /label="BM536_RS44130_Condensation_LCL.1"
                     /locus_tag="BM536_RS44130"
                     /protein_end="221"
                     /protein_start="38"
                     /score="190.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIACDG"
                     /tool="antismash"
                     /translation="PLPLSFAQRRLWILDRLQPGGTEYLMTVALRLRGPLDRAALRTAL
                     DGILHRHEVLRTRYPVVDGEPVQIVDEPGSVPLDEEDLGALDRTAADARIAALATGARR
                     PVDLAEGPVFSTVLARLAPQEHALLLTVHHIACDGRSEDVLVRELAERYEDAVAGRPTR
                     SPEPPVQYADFALWQRERLS"
     CDS_motif       9387..9419
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS44130_0001"
                     /evalue="2.20E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="BM536_RS44130"
                     /protein_end="53"
                     /protein_start="42"
                     /score="10.6"
                     /tool="antismash"
                     /translation="SFAQRRLWILD"
     CDS_motif       9444..9554
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS44130_0002"
                     /evalue="5.70E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="BM536_RS44130"
                     /protein_end="98"
                     /protein_start="61"
                     /score="50.9"
                     /tool="antismash"
                     /translation="YLMTVALRLRGPLDRAALRTALDGILHRHEVLRTRYP"
     CDS_motif       9768..9833
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS44130_0003"
                     /evalue="4.90E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="BM536_RS44130"
                     /protein_end="191"
                     /protein_start="169"
                     /score="28.7"
                     /tool="antismash"
                     /translation="VHHIACDGRSEDVLVRELAERY"
     CDS_motif       9882..9920
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS44130_0004"
                     /evalue="2.90E-07"
                     /label="C4_LCL_164-176"
                     /locus_tag="BM536_RS44130"
                     /protein_end="220"
                     /protein_start="207"
                     /score="22.7"
                     /tool="antismash"
                     /translation="QYADFALWQRERL"
     gene            10054..>10215
                     /locus_tag="BM536_RS44135"
                     /pseudo=""
     CDS             10054..>10215
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="BM536_RS44135"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 1.3e-13, bitscore:
                     40.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPADTARRLTTLAREHGATPFMALLAAHAVLLGRWSGRRDVAVGF
                     PVAGRDRSQ"
     gene            10296..13952
                     /locus_tag="BM536_RS43635"
     CDS             10296..13952
                     /NRPS_PKS="Domain: AMP-binding (158-551). E-value:
                     4.7e-119. Score: 389.5. Matches aSDomain:
                     nrpspksdomains_BM536_RS43635_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (653-719). E-value: 1.1e-20. Score:
                     65.6. Matches aSDomain: nrpspksdomains_BM536_RS43635_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (751-1053). E-value:
                     1e-40. Score: 131.6. Matches aSDomain:
                     nrpspksdomains_BM536_RS43635_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="BM536_RS43635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_281258626.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-131, bitscore:
                     428.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-12, bitscore:
                     37.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1e-33, bitscore:
                     106.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQVRERALDAYAHQEIPFERLVEELAPERDPSRTPLFSSMLLWQ
                     DAAGSPAPAAMGPLTAERLPVGESTAKFDLTVGLTEQSDGSLSGGVNYASALFDPATAE
                     RFAAQFTHLLESATVSPDTPVDELEILPAAERHRQLVDWNATGRDYPAGTLPLLFETQA
                     ARTPDADAVRFEGAALSYRDLDERADLLARHLRTLGVGPESVVGVCLHRGTDLVVALLA
                     VLKAGGAYLPLDPDYPADRLAFMLEDSGALAVVTDPRLAPLVRDRAPHLVDITADPPRG
                     RAHDPLVAAAPEHPAYLIYTSGSTGRPKGVLIEHRAIVNRLHWMQEAYGLGADDRVLQK
                     TPYGFDVSVWEFFWPLSTGATLVLARPGGHRDPAHLAELIGTEAITTVHFVPSMLRAFL
                     AEPLPALPSLRRMVCSGEALPADLVTAVHERIGCELHNLYGPTEAAVDVTATRCEPGLP
                     VTIGRPIANTRTYILDASLRPVPIGVPGELLLGGVQLARGYLNRPTLTADRFVPDPFAT
                     EPGGRLYRTGDLARYRADGAIEYLGRLDHQVKIRGQRVELGEIEAVLTEAPGVAAAAVA
                     VHDEQLVGYLVPPSADVEAAREHLRGRLPEHMRPVHWTLLETLPLTPSGKTDRTALPAP
                     DRTRSDLVGEFTAPGTAIERTLADAFATALGVDKVGVHDGFFQLGGDSMRAIRAVGALR
                     DQGLTLTVQDVFARQTVAELAPLAAAGPAAEPQETTLAGRFELLAPGDRDRLPERLVDA
                     YPMGEVQAGMVYEMLADPERNTYQNVSTFQILDDGPFSAEAFTGAVRLLIERHEILRTS
                     FDLTGYSEPLQLVHAADGLEAEVGVTDLRGLPTEEQRARVRDFRAEAQRTPFDVGRAPL
                     LRYHAHLVGDREWLLTHVECHAILDGWSHHSVIGELRTLYRELSRGTAAPTAPPAAGPL
                     RRLRPAREAGPGLAGGPGVLAGADHRPRAAPAAADSALAERDSPAPEVRLPWSHLEPRL
                     RRLAADTRTSLKSVLYTAHLKVLGLISGQHRFFAGAVTNGRPELPGGDRVRGMYLNTVP
                     FAVDLRAPSWRELVRSVFAEELALWPHRRYPLPAMQRAWGGGEPLVEVVFAYLDFHVLD
                     ERRADIGTVDDHSPNEFTFDVWTFPGELRMTCRPGWAGQERLAAIGDAFLAVLTAMADD
                     ADADPRGFRAPGLDRADETPTTTCPLPEVCVPELLATRVARRRPRWRTGGGE"
     CDS_motif       10308..10421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0001"
                     /evalue="1.50E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BM536_RS43635"
                     /protein_end="42"
                     /protein_start="4"
                     /score="68.8"
                     /tool="antismash"
                     /translation="RERALDAYAHQEIPFERLVEELAPERDPSRTPLFSSML"
     aSDomain        10770..11948
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43635_AMP-binding.1"
                     /evalue="4.70E-119"
                     /label="BM536_RS43635_AMP-binding.1"
                     /locus_tag="BM536_RS43635"
                     /protein_end="551"
                     /protein_start="158"
                     /score="389.5"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="FETQAARTPDADAVRFEGAALSYRDLDERADLLARHLRTLGVGPE
                     SVVGVCLHRGTDLVVALLAVLKAGGAYLPLDPDYPADRLAFMLEDSGALAVVTDPRLAP
                     LVRDRAPHLVDITADPPRGRAHDPLVAAAPEHPAYLIYTSGSTGRPKGVLIEHRAIVNR
                     LHWMQEAYGLGADDRVLQKTPYGFDVSVWEFFWPLSTGATLVLARPGGHRDPAHLAELI
                     GTEAITTVHFVPSMLRAFLAEPLPALPSLRRMVCSGEALPADLVTAVHERIGCELHNLY
                     GPTEAAVDVTATRCEPGLPVTIGRPIANTRTYILDASLRPVPIGVPGELLLGGVQLARG
                     YLNRPTLTADRFVPDPFATEPGGRLYRTGDLARYRADGAIEYLGRLDHQVKIR"
     aSModule        10770..12452
                     /complete
                     /domains="nrpspksdomains_BM536_RS43635_AMP-binding.1"
                     /domains="nrpspksdomains_BM536_RS43635_PCP.1"
                     /locus_tags="BM536_RS43635"
                     /monomer_pairings="Ser -> Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10956..10997
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0002"
                     /evalue="7.80E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="BM536_RS43635"
                     /protein_end="234"
                     /protein_start="220"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       11181..11240
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0003"
                     /evalue="1.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="BM536_RS43635"
                     /protein_end="315"
                     /protein_start="295"
                     /score="32.9"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGRPKGVLIEH"
     CDS_motif       11736..11825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0004"
                     /evalue="6.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="BM536_RS43635"
                     /protein_end="510"
                     /protein_start="480"
                     /score="53.7"
                     /tool="antismash"
                     /translation="PIGVPGELLLGGVQLARGYLNRPTLTADRF"
     CDS_motif       11913..11978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0005"
                     /evalue="1.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BM536_RS43635"
                     /protein_end="561"
                     /protein_start="539"
                     /score="39.3"
                     /tool="antismash"
                     /translation="YLGRLDHQVKIRGQRVELGEIE"
     aSDomain        12255..12452
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43635_PCP.1"
                     /evalue="1.10E-20"
                     /label="BM536_RS43635_PCP.1"
                     /locus_tag="BM536_RS43635"
                     /protein_end="719"
                     /protein_start="653"
                     /score="65.6"
                     /tool="antismash"
                     /translation="ERTLADAFATALGVDKVGVHDGFFQLGGDSMRAIRAVGALRDQGL
                     TLTVQDVFARQTVAELAPLAA"
     aSDomain        12549..13454
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43635_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.00E-40"
                     /label="BM536_RS43635_Condensation_DCL.1"
                     /locus_tag="BM536_RS43635"
                     /protein_end="1053"
                     /protein_start="751"
                     /score="131.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: CHAILDG"
                     /tool="antismash"
                     /translation="DAYPMGEVQAGMVYEMLADPERNTYQNVSTFQILDDGPFSAEAFT
                     GAVRLLIERHEILRTSFDLTGYSEPLQLVHAADGLEAEVGVTDLRGLPTEEQRARVRDF
                     RAEAQRTPFDVGRAPLLRYHAHLVGDREWLLTHVECHAILDGWSHHSVIGELRTLYREL
                     SRGTAAPTAPPAAGPLRRLRPAREAGPGLAGGPGVLAGADHRPRAAPAAADSALAERDS
                     PAPEVRLPWSHLEPRLRRLAADTRTSLKSVLYTAHLKVLGLISGQHRFFAGAVTNGRPE
                     LPGGDRVRGMYLNTVPFAVDL"
     aSModule        12549..16435
                     /complete
                     /domains="nrpspksdomains_BM536_RS43635_Condensation_DCL.1"
                     /domains="nrpspksdomains_BM536_RS43640_AMP-binding.1"
                     /domains="nrpspksdomains_BM536_RS43640_PCP.1"
                     /domains="nrpspksdomains_BM536_RS43640_Thioesterase.1"
                     /final_module
                     /locus_tags="BM536_RS43635"
                     /locus_tags="BM536_RS43640"
                     /monomer_pairings="Val -> Val"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       12654..12734
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0006"
                     /evalue="1.70E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="BM536_RS43635"
                     /protein_end="813"
                     /protein_start="786"
                     /score="30.1"
                     /tool="antismash"
                     /translation="DGPFSAEAFTGAVRLLIERHEILRTSF"
     CDS_motif       12969..13028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0007"
                     /evalue="4.80E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="BM536_RS43635"
                     /protein_end="911"
                     /protein_start="891"
                     /score="12.8"
                     /tool="antismash"
                     /translation="HAILDGWSHHSVIGELRTLY"
     misc_feature    13197..13199
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       13365..13442
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43635_0008"
                     /evalue="1.70E-04"
                     /label="C5_DCL_263-294"
                     /locus_tag="BM536_RS43635"
                     /protein_end="1049"
                     /protein_start="1023"
                     /score="14.1"
                     /tool="antismash"
                     /translation="GAVTNGRPELPGGDRVRGMYLNTVPF"
     aSDomain        13949..15082
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43640_AMP-binding.1"
                     /evalue="1.10E-106"
                     /label="BM536_RS43640_AMP-binding.1"
                     /locus_tag="BM536_RS43640"
                     /protein_end="378"
                     /protein_start="0"
                     /score="348.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="MTYRELDARSNQLAHLLRGLGTGPEKPVALCLDRGIEAVVAMLAV
                     LKAGGYYVPLDPGYPDARIRYVLDDVGAGVVLCRPQDTARLAGFAGLRSVPLDAASAVL
                     DGLPETPVEAGTVPDNLAYVTYTSGSTGRPKGVQVTHRGIVRLVHDANYADLDPDQVLL
                     LHAPLAFDASTLEVWGALANGARLAVCPPGATTADELAEVVRRHGVTVLWLTAGLFQHM
                     VETCPEVLADVRQVLAGGDALSPSHVRDALAHGVALTNGYGPTECTTFSTALRGVTEAD
                     ADRGVPIGTPITDTRVLVVDEDLDPVPTGVPGELLVGGPGLARGYLGRPDLTADRFVPD
                     PAGTVPGARLYRTGDITRRDADGTLSFIGRRDRQVKIR"
     gene            13949..16477
                     /locus_tag="BM536_RS43640"
     CDS             13949..16477
                     /NRPS_PKS="Domain: AMP-binding (0-378). E-value: 1.1e-106.
                     Score: 348.8. Matches aSDomain:
                     nrpspksdomains_BM536_RS43640_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (487-555). E-value: 4.1e-24. Score:
                     76.6. Matches aSDomain: nrpspksdomains_BM536_RS43640_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (572-829). E-value:
                     8.9e-33. Score: 106.5. Matches aSDomain:
                     nrpspksdomains_BM536_RS43640_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="BM536_RS43640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_245874001.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-118, bitscore:
                     385.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-17, bitscore:
                     52.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 4.5e-32, bitscore:
                     101.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRELDARSNQLAHLLRGLGTGPEKPVALCLDRGIEAVVAMLAV
                     LKAGGYYVPLDPGYPDARIRYVLDDVGAGVVLCRPQDTARLAGFAGLRSVPLDAASAVL
                     DGLPETPVEAGTVPDNLAYVTYTSGSTGRPKGVQVTHRGIVRLVHDANYADLDPDQVLL
                     LHAPLAFDASTLEVWGALANGARLAVCPPGATTADELAEVVRRHGVTVLWLTAGLFQHM
                     VETCPEVLADVRQVLAGGDALSPSHVRDALAHGVALTNGYGPTECTTFSTALRGVTEAD
                     ADRGVPIGTPITDTRVLVVDEDLDPVPTGVPGELLVGGPGLARGYLGRPDLTADRFVPD
                     PAGTVPGARLYRTGDITRRDADGTLSFIGRRDRQVKIRGHRVEPAEVEAALGGLPSVRA
                     AAAAVHPGPDGHKRLVGYVVLEAGHGPLDVATLREQLRRQVPDYLVPGAWAELAALPLT
                     ANGKIDRAALPMPAGPAATSAHTPPRTPAERAVAEVWGEVLGVERVGADDDFHVLGGHS
                     LAVLRIIALLRERHGIELTVRSFLEHPTVAGLAAAAEAGAPAARSLVWLRREGTRPPLF
                     CVHPGGGSAHWYRPLVRYLDPDQPVAAFAWPGLQAEHGPVPSTERMAERYLAELRAETP
                     HGPYRLFGWCGGSGIASEMAHRLTAEGEEVTFILLDPGLDNHERIELWREYWLIESCVA
                     KLTELAAAPPEQDTAALRAEALALLEHLVDDVDPEVGITLPEHGAGEVWLPSAKMWREV
                     MEMCLAYRHRPYAGRLHLIASDELADGEHEVASGQSFPDYLARWQRLTEDVTLHRIPGD
                     HFGVMKPPHLGRLAEAVTGILDGGDAEGTG"
     CDS_motif       14075..14116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0001"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="BM536_RS43640"
                     /protein_end="56"
                     /protein_start="42"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LAVLKAGGYYVPLD"
     CDS_motif       14216..14242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0002"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="BM536_RS43640"
                     /protein_end="98"
                     /protein_start="89"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="AGLRSVPLD"
     CDS_motif       14312..14371
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0003"
                     /evalue="5.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="BM536_RS43640"
                     /protein_end="141"
                     /protein_start="121"
                     /score="31.3"
                     /tool="antismash"
                     /translation="AYVTYTSGSTGRPKGVQVTH"
     CDS_motif       14870..14959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0004"
                     /evalue="2.00E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="BM536_RS43640"
                     /protein_end="337"
                     /protein_start="307"
                     /score="55.2"
                     /tool="antismash"
                     /translation="PTGVPGELLVGGPGLARGYLGRPDLTADRF"
     CDS_motif       15047..15112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0005"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="BM536_RS43640"
                     /protein_end="388"
                     /protein_start="366"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FIGRRDRQVKIRGHRVEPAEVE"
     aSDomain        15410..15613
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43640_PCP.1"
                     /evalue="4.10E-24"
                     /label="BM536_RS43640_PCP.1"
                     /locus_tag="BM536_RS43640"
                     /protein_end="555"
                     /protein_start="487"
                     /score="76.6"
                     /tool="antismash"
                     /translation="ERAVAEVWGEVLGVERVGADDDFHVLGGHSLAVLRIIALLRERHG
                     IELTVRSFLEHPTVAGLAAAAEA"
     aSDomain        15665..16435
                     /ASF="active site serine present: False"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS43640_Thioesterase.1"
                     /evalue="8.90E-33"
                     /label="BM536_RS43640_Thioesterase.1"
                     /locus_tag="BM536_RS43640"
                     /protein_end="829"
                     /protein_start="572"
                     /score="106.5"
                     /tool="antismash"
                     /translation="PPLFCVHPGGGSAHWYRPLVRYLDPDQPVAAFAWPGLQAEHGPVP
                     STERMAERYLAELRAETPHGPYRLFGWCGGSGIASEMAHRLTAEGEEVTFILLDPGLDN
                     HERIELWREYWLIESCVAKLTELAAAPPEQDTAALRAEALALLEHLVDDVDPEVGITLP
                     EHGAGEVWLPSAKMWREVMEMCLAYRHRPYAGRLHLIASDELADGEHEVASGQSFPDYL
                     ARWQRLTEDVTLHRIPGDHFGVMKPPHLGRLAEAV"
     CDS_motif       15668..15697
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0006"
                     /evalue="5.70E-04"
                     /label="NRPS-beforete1"
                     /locus_tag="BM536_RS43640"
                     /protein_end="583"
                     /protein_start="573"
                     /score="12.7"
                     /tool="antismash"
                     /translation="PLFCVHPGGG"
     CDS_motif       15851..15922
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS43640_0007"
                     /evalue="2.30E-09"
                     /label="NRPS-te1"
                     /locus_tag="BM536_RS43640"
                     /protein_end="658"
                     /protein_start="634"
                     /score="29.7"
                     /tool="antismash"
                     /translation="PHGPYRLFGWCGGSGIASEMAHRL"
ORIGIN
        1 gggcggcgga gccgcggccg ggcccggggc cggcgggcac cgcgccggtg ggccgggcgc
       61 ggcgcgtacg gagcgggcga gggaggcggc gccggcgatc acgaccatcc agcccgcgag
      121 ggccagcgcg gcggtccgcg cgccggccga gtcgagcagc aggccgccga gcagcgagcc
      181 gaccggcagt gccccgttgg acagggtgct cgtggccgcg agcacccggc cgcgcaacgg
      241 gtccggggtg atgctcagtt ggtagctgcc gagcgccacg ttccacaggg gtccgacgaa
      301 ccacatcgcg gcgtaggcgg cggtgagcgt gaacgggtcg cggctgaggg cgatcacggc
      361 catcagcacc gtccaggccc agttcgcccc gatcaccagg gtgccagtcc gacccggcgg
      421 gcgaaccacg gcgctgccag cgagccgagg acgcccccgg cccccgcgaa gccgaccatc
      481 aggcccaccc ccgtcgagga cgcgccgatg tcggtggcca gcacgatggc gaccaggaac
      541 agcgcccgga acatcaggtt gctgccggcc accagcaggg tggtggtgcg caggaagggc
      601 tgtcgccaca gccacctcag gccttcgtgg acctgctcgc gcatgctgcc ggtgcgggcg
      661 gaccgcttgg cctcgaactc cttgcggatg aacagcagtc cggtcagcga gaccagatag
      721 gtcagcgcgt cggccaggaa cgggacggcc cggccgagac cgaacagcat gccgccgagc
      781 ggtgtcccga gcatcacggc ggcccgcccc cgcgcctcgt tgcgggacag ggccagcgag
      841 agctggctcg gcggtacgac gttcgggacg gccgcgtgcg cggcgagccc gtggaacacc
      901 gtgagcgcgc cctcggcgaa gcccacggcc agcaccagcg gcaggcccag gacgtcgagg
      961 gcggacgcga ccgcgatggt cgccgcgccg agcgcgcgca gtgcgtcgca ccagatcatc
     1021 aaccgtcggc gcggccagcg gtccaccagg gcgccggccg gcagcgggag cagcagcgcg
     1081 ggcagcagtg tcacgaatcc cgccagcccg gcggcgaacg gcgagccggt gatggccaag
     1141 accagcagcg ggtaggcgat ggtggtggcg gtcgagccga gctgggagac cgccgagccg
     1201 ccccacagca gcaggaagtc gcggttgcga tgcagcggga ccaccggatc gtcggtggcc
     1261 gcgtccggcg ggtccggcgg ccgcgggtcc gccgacgccc tcgtgtcggg gctcgtcatc
     1321 tgtcacactc ccagtccggc tcgggccgga cgctagacgc gcgccgcctg ccccatctgc
     1381 cggcgcagac tgagcggtcg catgtcggtc cagacggtgc cgatgtgggc caggcactcg
     1441 gcccgggtcc cctcggtgcc ctcggcgtgc cagccgagcg gcagctcgcg gtcggcgagc
     1501 cagacggagt actgctcctc gtcgttgagg acgacgcggt acgtacgctc gtcgatgtct
     1561 tcctcggcca ctgcgggccc tccctcgggt gaactgccgc gtcacgaacc tcacgtgacg
     1621 gggggcggcg ccggagagcc tgccgcaacc gcccctgccg gtcccagaga aggaggcgca
     1681 gtcaccgcgg cgccgacgct gccgacgtga ctgccggttg ttctctcgga gcggcgacgg
     1741 cccggcggcg acgctgaggc gcatgactgc gaacccctcc gtccggaccg cgccggccga
     1801 ccgcgcccag gagcgcgacg cgagttccgc cctgcccctg acactgtcgg ccgagtcccc
     1861 cggcacgccc ctgtccgagt acctgtcggc cgcccggccg ctcgtccgcg gccggctgct
     1921 cgaacacggc gcggtactgc tgcgcggttt cgacgtcggc ggtgtggacg gcttcgaggc
     1981 cgcggtgcgg gcggtgtccg gcgcgccgct gccctacgcg gagcggtcct cgccacgcag
     2041 caccatcaag gggcaggtgt acacctcgac cgactatccg ccggacgagg agatcttcct
     2101 ccacaacgag aactcctacc aggcggactg gccgctgacc ctgttcttcc actgtgtgca
     2161 gccgccggac accctgggcg ccacgccgct cgccgacacc cgccgggtgt accgggcgat
     2221 cgacccgtcc gtccgggagg agttcgccgc ccggggctgg atggtcgtgc gcaacttctc
     2281 cgacggtttc ggcgtgccgt ggcagcaggc cttcggcacg gacgaccgcg gcgaggtcga
     2341 ggcgtactgc gcccgcaacg gcgtcgagac cgagtggacc gcggacggcc tgcggacccg
     2401 cgcgcgccgc cgggcggtgc accgccaccc ggtgaccggg gagacggtct ggttcaacca
     2461 cctcaccttc ttccacgtga ccacgctggc cgaggaggtg tgcggcgcgc tgcgggagat
     2521 gtacgacgac gcgcgactgc cgaccaacac ctactacggc gacggccggc cgatcccgga
     2581 cgaggtcgtc gcccacctgc ggtcctgcta ccgcgccgag cagcggcgct tcgactggcg
     2641 gcgggacgac gtgctcctcg tggacaacat gctgtcggcg cacgcccgcg agccgttcac
     2701 cgggccgcgc cggatcgccg tggcgatggc cgagcccttt tcggcggccg cgcggtccgc
     2761 cgcgttcgcg gaggtgaccg atgtccgccg atgacagcgg cctcccgctc tcgttcgccc
     2821 aggaacagct gtggttcctc gaccagctcc gctccggtgc ctccaccgag tacctgatgt
     2881 gcgaggcgtt ccgtatccgc ggcccgctcg acacgcgggt gctggaggcg gccttcaccg
     2941 agatctcggc gcggcacgag gtactgcgta cccgctacgg caccgccaca ggcgccgggg
     3001 cgcagttcgt ggacgagccc ggtcccgtgc ggctcgcccg ggtggacctg accggcacgg
     3061 cgccggcgga ccgtgaggcg cgcgtgcgcg aactccacgc ggccgagctg cgcacgccga
     3121 tcgacctccg tgaccgggcg ccctggcggc tgaccctggt ccggttcgcc gaggaggacg
     3181 ccgccctgct cgtgacggtc catcacatcg ccttcgacgg ctggtcctgg ggcgtcctcg
     3241 cccgggaact gcacgagctg tgcaccgcgt tcgcggcggg ccggccgtcg cagctcgaac
     3301 cggtacccgt gcagtacgcg gacttcgcgc agtggcagcg cgacacctgg gctgccgcgc
     3361 ccgagcgggc cgggcggcgg cgcggctact ggcgggagcg gctggcgggc ctggagccgc
     3421 tggagctgcc cgccgaccgc cggcgccccg cgcagtggga cccggccggg gacagcgtcg
     3481 cgttcacggt gccggcggag ctggccgggc ggctggcggt ggtcggccgg gacgcgggcg
     3541 cgaccccgtt catggtgcac ctggccgcgt tccagctgct gctcgcgcgc tggtccggcc
     3601 ggaccgacgt ggccgtcggc gtgtcggtct cggaccgcaa cgaggtcgaa ctggagccac
     3661 tggtcggcct cttcctcaac accgtcgtga tgcgcaccga cctgtcgggc cgctgctcgt
     3721 tcctcgacct gctggcgcgg gtccgggaga ccaccctcga cgcatacgag caccaggacg
     3781 tgccgttcgg ctgggtggtg gccgatctcg cgcccgagcg ggacccttcc cgcaacccgg
     3841 tgttccaggt cggcttcgcg ctgcacaacg ccgagcgccg cccactgcgg ctgcccggac
     3901 tcgacgtcgc gaaggtcgag ccggccaccg accactccgc cttcgacctg tcgctgcacc
     3961 tgtccgaact cccggacggc tcgatggcgg cccggctgat cttccccacc gcgctgttcg
     4021 accgcgcgcg gatcgagcgg atggcggcga gcctgctgcg gctgctgacg agcatcgccg
     4081 agcacccgga cctccccgcg cacgcactgg agaccgtccc cgtcacggag ctggcggcct
     4141 tcgagcgctg gaaccgcacc gggaccgagc gtccgcggca gtcgctcgcc gaactgttct
     4201 tcgcccaggc cctggccacc ccggaagcgg tggcgtggtg tccggcgagc gggtgaccgg
     4261 ctacgccgag ctggccgacc gggtgcggcg tctggccgga ctgctgcgct cgcgcggcgt
     4321 cggcccggag agcgcggtgg gcgtcgcgct gcaccgcggg accgacctgg tcgccaccgt
     4381 cctcgcggtg ctcaccgcgg gcggggtgta cgtgccgctg gcgccggaac accccgcgga
     4441 gcggctggcc cacctggtca ccgacgccga agtgaccctg ctggtcaccg aggaggcgct
     4501 ttccgggcgg ctgccggccc acccgaacac tctcgtgctc gacgcggtcc ggccggggga
     4561 ggacgaggag gccccgctcc tcgaaccggc gggcggggtc ggcacgcagg ccgcctacgt
     4621 gatgtacacc tccggttcga ccggccggcc caagggcgtc gtcgtaccgg aagccgcgat
     4681 ccgcaaccgc gtgctctggt cggtggagcg cttcggcctc ggccccggcg accgggtgct
     4741 gcagaggacc accatcggtt tcgacgccgc cgtgtgggag ttcctctccc cgttggtgtg
     4801 cggggccgcg gtggtgacgg gcccgcggga cgcccaccgc gacccggcgg tgatggtccg
     4861 tgccgtggtc gaccaccggg tcaccgtgct gcagggcgtg ccctcgatgc tgcgcctgct
     4921 gctggaggag ccggccctgg ccgactgcgc cgcactgcgc cttctgtgct cggcgggcga
     4981 gccgctgccc gccgaactgg ccgaccggct gcgccgcgcc ctcgacgccg aggtggtcaa
     5041 cacctacggc cccaccgagt gcgccgtgga ctccaccgcc tggcacttcg acccggacga
     5101 gcccggcgac ctggtgccga tcggcctgcc gctgcccaat gtgcgcacct acgtggtgga
     5161 cgccgagggc ctgccggtgc ccgtcggggt gaccggtgag ctgtacgtcg gcggcatcgg
     5221 gctcgcccgc gggtacgcgg gccggggcga cctcaccgcg gaccggttcg tccccgaccc
     5281 ggacgcgacc gtgcccggcg cgcgccggta ccgcaccgga gacctggtgc ggcgccgggc
     5341 ggacggcgcg ctggagtacg tgggacgcgt cgacgaccag gtcaagatcg gcggagtgcg
     5401 gatcgagccc ggggagatcg aggtcctgct ggcggcccac ccgtcggtgg ccgccgccgc
     5461 ggtggccgtg caccggtccg ccgcgggcga cgcgcggctg accgcgtacg cggtgcccgc
     5521 cgcgggggag cggatcgatc cggaggcgct gcgcgtccac ctggccgccg cgctgccgga
     5581 ggcgatgctg ccgtccgcct tcgtcggact cgccgagctg ccgctcacgc cgaacgggaa
     5641 ggtggaccgc cgccggctgc cggccgccac cgaaccggac cggcccgccg cggaggcccg
     5701 gcaggccccg cgcaccgcgg ccgaggagac cgtcgccgag ctgatggccg agatcctcgg
     5761 cgtcgagcgg gtcggcgcgc acgacgactt cttcctgctg ggcggccact ccctgctcgc
     5821 gatcaggctc gtgctgcggc tgcggcgcgc cttcggcagc gaactgaccg tcggcgagct
     5881 gttccaggcg cggacggtgg ccgcgctggc cgcccgggtc accgaggccg gcgccggctc
     5941 gcggaccgcc ctggacggcg atcccgacgc cgatccggac gccgtccggc cggcgggccg
     6001 ggaccgcccg ctgccgctct cgttcggcca gcagcggatg tggttcctcg accagctgga
     6061 gcccgggacg tacgagtacg tcgtcccgct ggcgctgcgg ctgaccggac cgctcgagac
     6121 cggggcgctg cgccacgcgc tggacgcgct gtccgaacgg cacgaggtac tgcggaccag
     6181 gtaccgctcc gagggtggcg agccggtcca ggtcgtcgac cccgccgggc cggtggactt
     6241 caccctgacc gatctgaccg gcgcgcccga cgccgagcac cgggcccggg ccctggtcga
     6301 cggactggcc cgtcaaccgt tcgacctcga acacgggcac ccgctgcggg cgagcctgat
     6361 ccgcaccggc cccgaggacc acctcctggt cctgaccctg caccacatcg ccttcgacgc
     6421 ctggtcgacc aacgtctacc tgcgcgacct cgacctctcc taccgggcct tcgccgcggg
     6481 cgagccgtcg ccgcacgccc cgcagccggt gcgctacgcc gacttcgcgg tgtggcagcg
     6541 cgagcagcag cgggccggcc ggctggacca ccagctcgcc tactggcgtg accgcctgga
     6601 cggcctcacg cccgtggagc tgcccacgga ccgggtccgc tcggccgtcc gcgacgcccg
     6661 gggcgacaac atcgtcgtcg aggtgccgcc ggaggtggcc cgggccgtcg ccgaactggc
     6721 cggccgacac ggcgcgaccc cgttcatggt gatgctcgcc gcgttccagg tgctgctgcg
     6781 gcgctggacc ggccgcgacg acctcgcggt ggggaccccg gtcgccggac ggacccgcca
     6841 ggagacggag gacatggtcg ggttcttcac caacaacctg gtgatccgca gcgacctcgg
     6901 cggcaacccg gtcttcggcg agctgctgga tcaggtccgc ggcacggtgc tcgacgcctt
     6961 cgcgcaccag gacgtgccgt tcgagcacct ggtcgacgcc ctgcagccgg agcgggacct
     7021 ctcccgcaac ccgctgttcc agatcatgtt cgaacaccag catctggcag gcgtccccga
     7081 ccggctcggc gcggtctccg tggagccggt ccgcgccgga ctggagaccg ccaagttcga
     7141 cctcaccgtg accgtcaagg agcgcggcgg gcgcatgtac tgctggttcg agtacgcgac
     7201 cgcgctcttc gaccgggaga ccgtcgagcg gatggcgggc cactacctga ccctgatcgc
     7261 cggcgtcacg gccgcccccg gcgcgcggat cggcgacctc gacatgctca ccggggacga
     7321 gcggcaccgc gccctgaccg cctgggccga ccccgggtcc gaacggacca ccgtgctcga
     7381 cccggccgag gaacacggac tgtgcgtacc ggagctgttc gcccggcagg tcaggcgggc
     7441 ccccgacgcg atcgccgtgg tcttcggcga ccagcaggtc agctacgccg aactcgacgc
     7501 ccgctccgcc cggttcgccg cccacctgcg ttccctcggg gtcaccgccg agacgatcgt
     7561 cggctcctgc ctggagcgcg gcgtggaggc ggtggtggtg ctgctcgccg tgctgagggc
     7621 cggcggcgtg tacgtgccgt tcgaccccgg gcaccccgcc gagcggctgc agctgatgct
     7681 cgccgacgcc ggcccggaac tcgtggtcac cacccgcgcg ttcgccgacc ggctgaccgg
     7741 cgcccaccgg gtggtcctgg ccgacgccga cgccgacgcc gacatcgacg ccgacgcccg
     7801 ggacgaaccc ggcacggcac ccgacggccc ggcgcccgtc ccgacccggc cgcacaacct
     7861 cgcctacgtc atctacacct ccggctcgac cggccggccc aagggcgtga tgatcgaaca
     7921 ccgtgcgtac gcccaccact gccgggtgat cgccgacgcg tacgggatcg cccccggcga
     7981 acgggtggca ctgctgtccg cgctcacctt cgacgtggcg atggaccaga tcgcggcgac
     8041 cctggtggcc ggcgccaccg tcgtcgtggc cgacccggtg ttctggaccc cggacgaact
     8101 gcccgcccgg ctcgccgagc acggcgtcac cgtcctggag atcaccccgt cctactaccg
     8161 ggccgtcctg gagtcgcccc acctgtccct gctggactca ctgaagctga tgaacgtcgg
     8221 cagcgacgtg gtcaccggcc tggacgcgcg gcgctggacc gaaaccggcc tgcccgcccg
     8281 cttcctgtgc aactacgggc cgaccgaggc caccgtcacc tgcctgctgc atcccgtccc
     8341 cgagaccccc gcggagggcg acgcggcggg cgccctgccg ctcggccggc ccgtccccgg
     8401 cacccgggcc tacatcctcg acgcggacct gcggcccgtc cccgtcggag tccccggcga
     8461 gctgtacctc ggcgcgtccg gctggcccgc ggctaccacc ggcgaccgga cctcaccgcg
     8521 gagcggttcg tccccgaccc cttcgccacc gagcccggcc ggcgcctcta ccgcaccggc
     8581 gacctgaccc gccaccggcc ggacggcacc atcgagttcc tcggccggat cgaccaccag
     8641 gtcaaggtcc gcggcctgcg catcgaactc ggcgagatcg aggcggcgct cgcccggcac
     8701 cccgccctcc aggaggcggt ggtcaccgcc ccgcggaccg ccccgggcga acgccggctc
     8761 gccgcctacc tggtggcgcg ccccgacagc ccgatgcccg gcgtggccga actgcgcgga
     8821 cacctgggcg cgctcctgcc cgagtacatg atcccctccg tatgggtgcc gctcgacgcg
     8881 ttcccgctga cggccagcaa gaagatcgac cgcaacgccc tgccggacgc ctcggccgca
     8941 ctggccggcg gcgcccgcga gcacctcgcc ccgcgagacc ccgccgagca ggccgtcgcc
     9001 gcgatctggt ccgaggtcct gggcctggag cggatcggcg cccaggacga cttcttcgcc
     9061 ctgggcgggc actcgctgct ggccacccgg gtactggccc ggctccgcga gacgttcgcc
     9121 gtcgagctgc ccctgcgcct gctgttcgag gccaccaccg tggcccggct ctccgaggcg
     9181 gtgtccgagg ccgtggaggc cgacgtcgcc gcgctctccg accaggaagt ggcgggcctg
     9241 ctcgccgagg aaggcctgcg atgaccgaca ccagggaccg cgcgcaactg cggcaggaac
     9301 tgctccgccg gcgcctcgcc gggcgggccg cccccgcccc ggcggagggc atcggccgcg
     9361 ccccgcgcgg cggcccgctc ccgctctcct tcgcccagcg ccgcctgtgg atcctcgacc
     9421 ggctccagcc cggcggcacc gagtacctga tgaccgtggc gctcaggctg cgcggcccgc
     9481 tcgaccgggc cgcgctgcgc accgcgctgg acggcatcct ccaccggcac gaggtgctgc
     9541 ggacccgcta cccggtggtc gacggagagc ccgtgcagat cgtcgacgag ccggggagcg
     9601 tccccctcga cgaggaggac ctcggcgccc tcgaccggac ggccgcggac gcccggatcg
     9661 ccgccctggc caccggcgcg cgcaggccgg tcgacctcgc cgagggcccg gtgttctcca
     9721 ccgtgctggc ccggctggca ccacaggagc acgccctcct gctcaccgtc caccacatcg
     9781 cctgcgacgg gcggtccgag gacgtcctgg tccgcgaact cgcggaacgc tacgaggacg
     9841 cggtcgccgg gcggccgacc cgctcgccgg aaccacccgt gcagtacgcc gacttcgcgc
     9901 tctggcagcg cgaacggctc tccggcgcgg cgctgcgccg cccgctggac cactggcgcg
     9961 aacgcctggc cggcctgccg cccctggagc tgcccaccga ccgccccccg tcccgccgta
    10021 cgcgactcgg cgggcggggt ggcgccgctc gccgtgccgg ccgacaccgc ccggcggctg
    10081 accacgctcg cgcgcgagca cggcgccacc cccttcatgg cgctgctggc cgcgcacgcc
    10141 gtcctgctcg gccgctggag cggccggcgc gacgtcgccg tgggcttccc ggtggcaggg
    10201 cgcgaccgct cacaactcga ggacctggtc ggcctcttcc tcaacacgct ggtgctgcgg
    10261 gtcgacctgt ccggggcgcc gtcttcgcgg acctggtgcg gcaggtccgc gaacgcgccc
    10321 tcgacgccta cgcccaccag gagattccct tcgagcggct cgtcgaggag ctggcaccgg
    10381 agcgggaccc gtcccgcacg ccactgttct cctccatgct gctgtggcag gacgcggccg
    10441 gctcgccggc gccggcggcg atgggccccc tgacggccga gcggctgccg gtgggcgaga
    10501 gcaccgccaa gttcgacctc accgtgggcc tcaccgagca gtcggacggc tcgctgtccg
    10561 gcggcgtcaa ctacgcctcg gcgctgttcg atccggcgac ggccgagcgg ttcgccgcgc
    10621 agttcaccca cctgctggag agcgcgaccg tctcgcccga caccccggtg gacgaactgg
    10681 agatcctgcc cgcggcggag cgccaccgtc agctcgtcga ctggaacgcg accggccggg
    10741 actacccggc cggcaccctc ccgctgctgt tcgagaccca ggcggcccgc acccccgacg
    10801 ccgacgcggt gcgcttcgag ggcgccgccc tcagctaccg ggacctggac gagcgggccg
    10861 acctgctcgc ccgccacctg cggacgctcg gcgtcggacc cgagtccgtg gtcggcgtct
    10921 gcctgcaccg gggcaccgac ctcgtggtgg cgctgctggc ggtgctcaag gcaggcggcg
    10981 cctacctgcc gctcgacccg gactacccgg ccgaccggct cgccttcatg ctggaggact
    11041 ccggcgccct ggccgtggtc accgaccccc gactcgcccc cctggtgcgc gaccgcgcgc
    11101 cgcacctggt cgacatcacc gccgacccgc cccgcggccg tgcccacgac ccgctcgtcg
    11161 cggcggcccc cgaacacccg gcgtacctga tctacacgtc gggctccacc ggccgcccca
    11221 agggcgtact gatcgagcac cgcgccatcg tcaaccggct gcactggatg caggaggcct
    11281 acgggctcgg cgccgacgac cgggtgctgc agaagacgcc ctacggcttc gacgtctcgg
    11341 tgtgggagtt cttctggccg ctgagcaccg gcgcgacgct ggtgctcgcc cgccccggcg
    11401 gccaccgcga cccggcccac ctggccgagc tgatcggcac cgaggcgatc accaccgtcc
    11461 acttcgtacc gtcgatgctg cgggccttcc tcgccgagcc gctgccggcc ctgccctcgc
    11521 tgcgccgcat ggtgtgcagc ggtgaggcgc tccccgccga cctggtcacc gccgtgcacg
    11581 agcggatcgg ctgcgagctg cacaacctgt acggaccgac cgaggccgcc gtggacgtca
    11641 ccgcgacccg gtgcgagccg ggcctgcccg tcaccatcgg ccgcccgatc gccaacaccc
    11701 gcacctacat cctggacgcc tccctgcggc cggtgccgat cggggtgccc ggcgaactcc
    11761 tgctcggcgg cgtccagctg gcccgcggct acctgaaccg tccgacgctc accgccgacc
    11821 gcttcgtacc cgaccccttc gccaccgagc ccggcgggcg gctgtaccgc accggcgacc
    11881 tggcccggta ccgcgcggac ggcgcgatcg agtacctcgg ccggctcgac caccaggtga
    11941 agatccgcgg ccagcgggtc gaactcggcg agatcgaggc ggtgctgacc gaggcccccg
    12001 gcgtcgccgc cgcggccgtc gccgtgcacg acgaacagct cgtgggatac ctggtgccgc
    12061 cctcggccga cgtcgaggcg gcccgcgagc acctgcgcgg acggctcccg gaacacatgc
    12121 ggcccgtgca ctggaccctg ttggagacgc tgcccctgac gcccagcggc aagaccgacc
    12181 gtacggcgct gccggcaccc gaccggacgc gctcggacct ggtcggcgag ttcaccgccc
    12241 cgggcacggc gatcgagcgg accctcgccg acgccttcgc cacggccctc ggcgtcgaca
    12301 aggtcggggt gcacgacggc ttcttccagc tcggcgggga ctccatgcgc gccatccggg
    12361 ccgtcggagc actgcgcgac caggggctga ccctcaccgt gcaggacgtc ttcgcccggc
    12421 agaccgtcgc cgagctggcc ccgctggcgg cagccggacc ggcggccgag ccgcaggaga
    12481 ccaccctggc cggccgtttc gaactgctgg cccccggcga ccgggaccgg ctcccggagc
    12541 ggctcgtcga cgcctacccc atgggcgagg tccaggcggg catggtctac gagatgctcg
    12601 ccgaccccga gcgcaacacc taccagaacg tcagcacctt ccagatcctg gacgacggcc
    12661 cgttctccgc agaggcgttc accggcgcgg tacgcctgct gatcgagcgg cacgagatcc
    12721 tccgcacctc cttcgacctc accgggtact ccgaaccgct ccagctcgtg cacgccgcgg
    12781 acggcctgga ggcggaggtc ggcgtcaccg acctgcgcgg cctgccgacc gaggagcagc
    12841 gggcgcgggt gcgggacttc cgcgccgagg cccagcgcac cccgttcgac gtcggccgcg
    12901 ccccgcttct gcgctaccac gcccacctgg tgggcgaccg ggagtggctg ctgacgcacg
    12961 tcgagtgcca cgccatcctg gacggctgga gccaccactc ggtcatcggc gagctgcgaa
    13021 ccctctaccg cgaactgtcc cgaggcaccg cggccccgac cgcgcccccc gccgcgggtc
    13081 cgctacgccg acttcgtccg gctcgagaag caggccctgg cctcgccggc ggaccgggag
    13141 ttctggcagg agcggatcac cggccacgag cggctccggc tgccgccgac agcgccttag
    13201 ccgagaggga ctcgccggcc cccgaggtac ggctgccctg gtcgcacctg gagccgcggc
    13261 tgcgcaggct cgccgccgac acccggacgt cactcaagag cgtcctgtac accgctcacc
    13321 tgaaggtgct gggcctgatc agcggccagc accggttctt cgccggcgcc gtcaccaacg
    13381 gccggcccga actgccgggc ggcgaccggg tgcgcggcat gtacctcaac acggtgccgt
    13441 tcgccgtcga cctgcgggcg ccgagctggc gcgagctggt gcggtcggtg ttcgccgagg
    13501 agctggccct gtggccgcac cggcgctatc cgttgcccgc gatgcagcgc gcatggggcg
    13561 gcggcgaacc gctcgtcgag gtggtcttcg cctacctcga cttccacgtg ctcgacgagc
    13621 ggcgcgcgga catcggcacg gtcgacgacc acagcccgaa cgagttcacc ttcgacgtgt
    13681 ggaccttccc cggcgagctg cgcatgacct gccggcccgg ctgggccggc caggagcggc
    13741 tggcggcgat cggcgacgcc ttcctggccg tcctcaccgc gatggccgac gacgccgacg
    13801 cggacccgcg tggcttccgc gcgcccggcc tcgaccgggc ggacgagacg ccgaccacca
    13861 cctgcccgct gcccgaggtc tgcgtgcccg agctgctcgc cacccgcgtc gcccgacggc
    13921 gaccgcgctg gaggacgggc ggcggcgaat gacctaccgg gaactggacg cccgttccaa
    13981 ccagctggcc cacctgctgc gcgggctcgg caccggcccg gagaagccgg tcgcgctctg
    14041 cctggaccgt ggcatcgagg cggtggtggc catgctcgcc gtcctcaagg ccggcgggta
    14101 ctacgtgccg ctcgaccccg gctacccgga cgcgcgcatc cgctacgtcc tggacgacgt
    14161 cggtgccggg gtggtcctgt gccgcccgca ggacaccgcc cgcctggccg ggttcgccgg
    14221 actccgcagc gtccctctgg acgccgcatc ggccgtcctc gacggactgc ccgagacccc
    14281 cgtcgaggcg ggcacggtcc ccgacaacct ggcgtacgtc acctacacct cgggatccac
    14341 cggccggccc aagggcgtgc aggtcacgca ccgggggatc gtccggctgg tgcacgacgc
    14401 gaactacgcc gacctcgacc cggaccaggt gctgctgctg cacgccccgc tcgccttcga
    14461 cgcgtccacg ctggaggtgt ggggagcgct ggccaacggc gcccggctcg ccgtctgccc
    14521 gccgggcgcg accacggccg acgagctggc cgaggtggtc cgccggcacg gcgtgacggt
    14581 gctgtggctc accgccggcc tgttccagca catggtggag acctgcccgg aggtgctggc
    14641 cgacgtacgg caggtgctcg ccggcggcga cgcgctctcg ccctcgcacg tgcgcgacgc
    14701 cctggcgcac ggcgtggcgc tgaccaacgg ctacggcccc acggagtgca ccaccttcag
    14761 caccgcgctg cgcggggtga ccgaggccga cgccgaccgc ggggtgccga tcggcacgcc
    14821 gatcaccgac acccgggtac tggtggtcga cgaggacctg gacccggtgc cgacgggggt
    14881 gcccggcgaa ctcctggtcg gcggccccgg cctcgcccgc ggctacctgg gccgccccga
    14941 cctgaccgcg gaccgcttcg tgccggatcc cgccgggacc gtccccgggg cgcgcctcta
    15001 ccggaccggg gacatcaccc gccgcgacgc cgacggcacg ctctccttca tcggccggcg
    15061 cgaccgccag gtgaagatcc gcggtcaccg ggtggagccg gccgaggtgg aggccgcgct
    15121 cggcggcctc ccgtccgtcc gggcggcggc ggccgccgta catccgggac cggacggcca
    15181 caagcggctg gtcggctatg tcgtccttga agcagggcac ggtccgctgg acgtcgcgac
    15241 gctgcgcgag caactccggc ggcaggtgcc cgactacctg gtgcccggcg cgtgggcgga
    15301 gctggccgca ctcccgctca ccgccaacgg gaagatcgac cgggccgcgc tgcccatgcc
    15361 cgccgggccc gccgcgacgt cggcgcacac gcccccgcgc acacccgccg agcgggccgt
    15421 ggccgaggtc tggggcgagg tgctcggcgt ggagagggtc ggtgccgacg acgacttcca
    15481 cgtcctcggc gggcactcgc tggccgtcct gcggatcatc gccctgctgc gcgagcggca
    15541 cggcatcgag ctgaccgtcc gttcgttcct ggagcacccc accgtggccg ggctcgccgc
    15601 ggccgccgag gccggcgcac cggcggcccg gtcactggtc tggctgcggc gcgagggcac
    15661 ccggccgccg ctgttctgcg tgcaccccgg gggcggcagc gcccactggt accgcccgct
    15721 ggtgcggtac ctcgaccccg accagccggt cgcggccttc gcctggcccg gcctgcaggc
    15781 cgagcacggc cccgtcccct cgaccgaacg gatggcggag cgctacctgg ccgagttgcg
    15841 ggccgagaca ccgcacggcc cgtaccggtt gttcggctgg tgcggcggca gcggcatcgc
    15901 gagcgagatg gcgcaccggc tcacggccga gggcgaggag gtcaccttca tcctgctcga
    15961 tccggggctg gacaaccacg agcggatcga gctgtggcgg gagtactggc tgatcgagag
    16021 ctgtgtggcg aagctgacgg agctggctgc cgcgccgccc gagcaggaca ccgcggcgct
    16081 gcgtgcggag gccctggctc tgctcgaaca cctggtggac gacgtcgacc cggaggtggg
    16141 gataacgctg cccgagcacg gcgccggcga ggtctggctg ccctccgcga agatgtggcg
    16201 cgaggtcatg gagatgtgcc tggcctaccg gcaccgcccg tacgcgggcc ggctgcacct
    16261 gatcgccagc gacgaactgg ccgacggtga gcacgaggtg gcctccgggc agtcgttccc
    16321 cgactacctc gcccgctggc agcggctcac cgaggacgtg acgctgcacc ggatccccgg
    16381 cgaccacttc ggcgtgatga agccgccgca cctcggccgg ctcgccgagg ccgtcaccgg
    16441 catcctcgac ggcggcgacg cggagggcac cggctgacac cgcggcggat ggcacggccg
    16501 ggagggcggg ggcgcgttga gcg
//
