LOCUS       NZ_MPOH02000020        21053 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces phaeoluteigriseus strain DSM 41896 Scaffold_20, whole
            genome shotgun sequence.
ACCESSION   NZ_MPOH02000020
VERSION     NZ_MPOH02000020.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 324429)
  AUTHORS   Salih,T.S., Algora Gallardo,L., Melo Santos,T., Filgueira
            Martinez,S. and Herron,P.R.
  TITLE     Draft genome sequence of Streptomyces phaeoluteigriseus type strain
            DSM41896
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 324429)
  AUTHORS   Salih,T.S., Algora Gallardo,L., Melo Santos,T., Filgueira
            Martinez,S. and Herron,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2017) Strathclyde Institute of Pharmacy and
            Biomedical Sciences, University of Strathclyde, 161 Cathedral
            Street, Glasgow G40RE, United Kingdom
REFERENCE   3  (bases 1 to 324429)
  AUTHORS   Schniete,J.K., Salih,T., Algora Gallardo,L., Martinez Fernandez,S.
            and Herron,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2016) Strathclyde Institute for Pharmacy and
            Biomedical Sciences, University of Strathclyde, 161 Cathedral
            Street, Glasgow G40RE, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-JAN-2017
            Assembly Method                   :: SPAdes v. 3.9; MeDuSa v. 1.6
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: IonTorrent
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001896135.2-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:12:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,918
            CDSs (total)                      :: 7,837
            Genes (coding)                    :: 6,622
            CDSs (with protein)               :: 6,622
            Genes (RNA)                       :: 81
            rRNAs                             :: 3 (5S)
            complete rRNAs                    :: 3 (5S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 1,215
            CDSs (without protein)            :: 1,215
            Pseudo Genes (ambiguous residues) :: 0 of 1,215
            Pseudo Genes (frameshifted)       :: 907 of 1,215
            Pseudo Genes (incomplete)         :: 407 of 1,215
            Pseudo Genes (internal stop)      :: 30 of 1,215
            Pseudo Genes (multiple problems)  :: 120 of 1,215
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:00:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 103567
            Orig. end                         :: 124620
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MPOH02000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1308..1324)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.58"
                     /tool="antismash"
     gene            complement(1402..2124)
                     /locus_tag="BM536_RS34895"
                     /old_locus_tag="BM536_034825"
     CDS             complement(1402..2124)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="BM536_RS34895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034825"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_073491328.1"
                     /transl_table=11
                     /translation="MDSTAATALPDLWDRLVGTQSDPDLWVVIATMAAALAVVVPHTLW
                     RLSRNAITIAHEGGHGLVALLTGRQLTGIRLHSDTSGLTLSRGKPHGLGMILTAASGYT
                     APPLLGLGGAALLGAGRITLLLWLATVLLVAMLVMIRNAYGVLTVVVTGGAFLLVSWLA
                     DAQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCALLGGGRWLLGL"
     gene            2175..2989
                     /locus_tag="BM536_RS34900"
                     /old_locus_tag="BM536_034830"
                     /pseudo=""
     CDS             2175..2989
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="BM536_RS34900"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034830"
                     /product="SOS response-associated peptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCGRYAASRQPEDLAGVFEIEKWEPEETLEPDYNVAPTKEVHVVL
                     DRPLKDVPDPRPVRQLRKLRWGLVPSWSKTPEGAARMINARAETVHEKPSFRRAFATRR
                     CIIPADGYYEWVTGQQERELEVEGRRKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPRAWWATCSVVTTDAETTPLAESPAEGPRTLYDIHPRMP"
     gene            3141..3728
                     /locus_tag="BM536_RS34905"
                     /old_locus_tag="BM536_034835"
     CDS             3141..3728
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119817.1"
                     /locus_tag="BM536_RS34905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034835"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_094103976.1"
                     /transl_table=11
                     /translation="MTWHRARRPRLVLAVSHGAGGGIEARDLRALAEVLPGHGVSVALV
                     EQPWRVAGRKVAPAPKTLDVGWRGIWPAVAKAGLPVISGGRSAGARVACRTAVELGAHA
                     VLALSFPLHPPGRPERSRAAELLGAGVPTLVVQGGNDPFGKPAEFPEGTYALVEVPYGD
                     HGFAVPKRAPVTQDQALETVTAAVLPWAVSLG"
     gene            3977..4672
                     /gene="sigR"
                     /locus_tag="BM536_RS34910"
                     /old_locus_tag="BM536_034840"
     CDS             3977..4672
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="BM536_RS34910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034840"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_211363006.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGQAELPEGQGTGVGTAAESTTERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKAALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SNEAKGSGS"
     gene            4669..4971
                     /gene="rsrA"
                     /locus_tag="BM536_RS34915"
                     /old_locus_tag="BM536_034845"
     CDS             4669..4971
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="BM536_RS34915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034845"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_073491330.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCGEVLDHLYEFLDSEMPDMDRDKFKQHFNECSPCL
                     EKYGLEEAVKKLVKRCCGHDDVPTDLRSKVMGRIELIRSGQAVPEHDVSVTPQES"
     gene            5211..6521
                     /locus_tag="BM536_RS34920"
                     /old_locus_tag="BM536_034850"
     CDS             5211..6521
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657918.1"
                     /locus_tag="BM536_RS34920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034850"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_094103950.1"
                     /transl_table=11
                     /translation="MDGIPVRARVYVGCAVLGALCCLFPLPSDRTRWWPVLLLAALYAG
                     GERVARRRFAGTLYPVLLAGAFLFPAAAAALVPLPGALLSPVEHRPFPLRRVWRAARLA
                     LGVWAASRAHEALGGREAVGASDGPALLLPAAAGVLVLCLVLAVLDGGILALAEGLPAR
                     RAWHGPFLRSLAPVGVHGLAGLMMAVLWHSPYGPVAALLVLFPMGVSWWVFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASLLIARELGMDEGRVEVIRFAGILHDVGK
                     LGVPTRLLRKKGPLTPEERRVIELHPEYGHEITRGISFLGEARSAILHHHERLDGSGYP
                     YGLVGSQIPEPARVVAVADAFDAMTSTRSYSRARPVPVALEELQRCAGAHFDPRMVTAL
                     TRVITRDGWHPIVTADEPRLPAQSPADPVPERPGARR"
     gene            6518..7777
                     /locus_tag="BM536_RS34925"
                     /old_locus_tag="BM536_034855"
     CDS             6518..7777
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058306.1"
                     /locus_tag="BM536_RS34925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034855"
                     /product="HD domain-containing protein"
                     /protein_id="WP_073491331.1"
                     /transl_table=11
                     /translation="MSGRRRAVRAGGLLSVLHGAAGLLVVASLFVVLRSGLAERPVALA
                     FGVLMAVGELTRWSGPGLREAAPLGSAASLSYALLGEHAGHATHHGVAQVVAVVVAASL
                     LGSVPHIARGQGPVLDHLVRRVLAVGFAAVCFQPLYNHGVFARWTGPAYALLLLALLVL
                     TALCDAVVAAALAHSRTGWPFAPLLRDELRSVPGLGSAVAATGAVMALAVAVVGLWALP
                     VFSVPLLLTQLSLRRYAAVRATYRQTIASLARATEIAGYTPAGHARRVAALCQAVGRDL
                     GLTEPELTVLEYAALMHDIGQLSLVDPVPAGATAGLPPAEQRRIALLGGAVVRQTGASA
                     QVAAVVECQADPYPEQPTAARIVRVVNAYEEKVRDAGPGGPLTALEELRLGTGGEYAPE
                     VVEALARVLSRDCLTLPAGG"
     gene            7883..8863
                     /locus_tag="BM536_RS34930"
                     /old_locus_tag="BM536_034860"
     CDS             7883..8863
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="BM536_RS34930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034860"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_094103951.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRETGAPDWWNVGIAATALQDWPLA
                     RRSWQAYGLHVPGGPTAAGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSVGHSYPVFDEIELWAPSPVPTWVVLLEAATETDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9020..9670
                     /gene="def"
                     /locus_tag="BM536_RS34935"
                     /old_locus_tag="BM536_034865"
     CDS             9020..9670
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="BM536_RS34935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034865"
                     /product="peptide deformylase"
                     /protein_id="WP_073491332.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGFVIDTGETEEREQAWRRAGTARPIT
                     VVGNPVLHKECKDVTEFGEELQQLVADMFASQHAAEGVGLAANQIGVDLKVFVYDCPDD
                     EGARHTGVVCNPKLVELPTERRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPV
                     RVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKEALRQMAENEPRYAVVPND"
     gene            10001..11053
                     /gene="cyc1"
                     /locus_tag="BM536_RS34940"
                     /old_locus_tag="BM536_034870"
     CDS             10001..11053
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009307568.1"
                     /locus_tag="BM536_RS34940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034870"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_073491333.1"
                     /sec_met_domain="T1TS (E-value: 9.9e-62, bitscore: 203.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVAVPASLSLPVIEAVFPRQLHPYWPQLQENTRAWLLEKRLMP
                     ADKVAEYADGLCYTDLMAGYYLGAPDEVMQAIADYSAWFFVWDDRHDRDVVHGRAAAWR
                     QLRRRLHVALDSPDEHLLHEDPLVAGLADSVGRLYSFLPATWSERFARHFHEVIEAYDR
                     EFHNRMDGRIPGVEEYLVLRRLTFAHWIWTDLLEPSAGCELPDAVRKHPAYRRAALLSQ
                     EFAAWYNDLCSLPKEIAGDEVHNLGISLIAHEGLTLEEAVEEIRRRVEDCISEFLVTEK
                     DVLRLADRLTDGTVHGKELGAAVRACLENMRNWFSSVYWFHHESGRYMVDSWDDRSTPP
                     YVNNEAAGEK"
     gene            11050..12420
                     /locus_tag="BM536_RS34945"
                     /old_locus_tag="BM536_034875"
     CDS             11050..12420
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="BM536_RS34945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034875"
                     /product="cytochrome P450"
                     /protein_id="WP_073491334.1"
                     /sec_met_domain="p450 (E-value: 1.7e-67, bitscore: 222.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVNPVTPVAPELREPPLAGGGVPLLGHGWKLARDPLAFMSQ
                     LRDHGDIVRIKLGPKTVYAVTTPALTGAMALSPDYIIAGPLWESLEGLLGKEGVATANG
                     PLHRRQRRTIQPAFRLDAIPAYGPIMEEETRALVERWQGGETIDCTSESFRIAVRVAAR
                     CLLRGQFMDERAERLCVALASVFQGMYHRMVVPLGPLYRLPLPANREFNRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIASTIMSL
                     LLVLADHPEQADKVCSEVRAVTGGRPVAFDDVRKLTHTNNVVIEAMRLRPAVWILTRRA
                     VADTELGGYRIPAGADIVYSPYAIQRDPRSYERHLEFDPDRWLPERSKDIPKYAMRPFS
                     VGNRKCPSDHFSMALLTLVTAVLADGFRFEQVPGSVDETRVGITLRPQRLRLKPVPR"
     misc_feature    11701..11703
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12446..13411)
                     /locus_tag="BM536_RS34950"
                     /old_locus_tag="BM536_034880"
     CDS             complement(12446..13411)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="BM536_RS34950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034880"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_073491335.1"
                     /transl_table=11
                     /translation="MLKNVAAILLDGVHPFELGVVCEVFGIDRSDEGLPVYDFAVASAE
                     GPTLSTPHPGFTMSTSHGLERLESADLIAVPAGDTYTAREFPPELLDALRRAVERGTRV
                     LSVCSGAFVLAAAGLLDGRRCAVHWRHAEQLAREYPRTTVEPDVLYVDEDPVITSAGTA
                     AGIDACLHLVRKEQGPEVANGIARRMVVPPHRDGGQAQYIQRPLPRSSCDTVGEVLAWM
                     EQHLAQEVTVEQLAARAHMAPRTFARRFQQETGTTPYRWLLRQRVLLAQHLLEASDETV
                     DAIAWRTGFGTAGALRHQFVRVLGTTPNAYRRTFRGPEAA"
     gene            complement(13621..14634)
                     /locus_tag="BM536_RS34960"
                     /old_locus_tag="BM536_034890"
     CDS             complement(13621..14634)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657910.1"
                     /locus_tag="BM536_RS34960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034890"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_073491337.1"
                     /transl_table=11
                     /translation="MTTRNQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLH
                     SDVTDLAKLTPAEQHLIGRLVAFFATGDSIVSNNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPEDRAAAFDAVESIPSIREKAEFCFRWMDSVEKLDRLESMSD
                     RRRFLLNLICFAACIEGLFFYGAFAYVYWFRGRGLLHGLATGTNWVFRDETMHMSFAFE
                     VVDTVRKEEPELFDDRLQEQVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECV
                     ADQRLSRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14634..17002)
                     /locus_tag="BM536_RS34965"
                     /old_locus_tag="BM536_034895"
                     /pseudo=""
     CDS             complement(14634..17002)
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="BM536_RS34965"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034895"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTIAPAEPVSAAPKTDGPGTALLRTLTELTADLPDADPGRVAAAA
                     LRGRSARADESELRELATEAAAGLISEDPAYSQLAARLLTIGIRAEAASQGVTTFTESV
                     AVGHREGLIADRTAEFVRLHAARLDALVDTGADDRFGYFGLRTLHSRYLLRHPITRKVV
                     ETPQHFLLRVASGLAEDDTTRSVDEVAALYTLMSRLDYLPSSPTLFNSGTRHPQMSSCY
                     LLDSPLDELDSIYDRYQQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNGIVPFLKT
                     LDASVAAVNQGAGARARPRCTWRPGTPTSRSSWSCATTPARTPAVRTTSTWRTGCRTSS
                     CAGSTTTGSGPCSPRPTCPSWSTCGARSSTRPTARRRPRGWPGRPSRRVSCTAA"
     regulatory      complement(17125..17268)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17258..17272)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17289..17303)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     gene            complement(17441..19069)
                     /locus_tag="BM536_RS34970"
                     /old_locus_tag="BM536_034900"
     CDS             complement(17441..19069)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="BM536_RS34970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034900"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_073491338.1"
                     /transl_table=11
                     /translation="MNGGVNGVALAVFIFFFLAVTVMGFLAARWRRADDEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFAKAGDAFSQTNPATGAPRGSLVPSEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSRDVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVSNGQLAIPQLFEDMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPREETRVSKLVSLLVKVGAL
                     AFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTVAAY
                     GVASPTQKHFGGSSKEIPGIGEIGYIGLTAFVLNVVVTVVLTFVMKALKAPEGVDETSP
                     SDYTADAGDPGVQVELPPATAGAGH"
     gene            complement(19066..19332)
                     /locus_tag="BM536_RS34975"
                     /old_locus_tag="BM536_034905"
     CDS             complement(19066..19332)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480428.1"
                     /locus_tag="BM536_RS34975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034905"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_094103952.1"
                     /transl_table=11
                     /translation="MSEAPEVNGGPVVTPLRVVIALCLFAPFVAMLWVGSYAKTDPAFI
                     GIPFFYWYQMLWVLLSTLLTVVAYKLWQVDQRGRRNQGGGAAK"
     misc_feature    complement(19401..19415)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            complement(19550..20314)
                     /locus_tag="BM536_RS34980"
                     /old_locus_tag="BM536_034910"
     CDS             complement(19550..20314)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="BM536_RS34980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_034910"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_073491340.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTETQSPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYGVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SVDREGLPVEWVRSVYRGDRYKFVARLKRPVD"
     misc_feature    20461..20476
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.11"
                     /tool="antismash"
     misc_feature    20462..20478
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.31"
                     /tool="antismash"
     misc_feature    complement(20632..20647)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
ORIGIN
        1 gcatcccggt ccacaggtcg gggaagtcgg gcagtgtctt cgccgtcgtc gccacgttct
       61 cgatctgtac gccctccacg gccaggccga tgatcgcgcc ggccgtggcc atgcggtggt
      121 cgtcgtaggt gtggaagatc ccgccgtgca gccggcgcgg gcggacgtgg aggccgtcgg
      181 cggtctcggt gacgtcgccg cccagctcgt tgatctcctt ggtgagggcg gccaggcggt
      241 ccgtctcgtg caggcgcagg tgcgagacgc cccgcagggt ggagggggag tcggcgaggg
      301 cggcgaccgc cgcgatgccc ggggtcagct cgccgacgtc gctcaggtcg acgtcgatgc
      361 cgtggatcgt gcccgacccg gtgaagacga ggccgtactc ggtcagttcg caggaaccgc
      421 ccatctcggt gaagatctcc cgcagccggt cccccggttg ggtggtcctg gccggccagt
      481 cggggacgac gacccggccg ccggtgacga gtgccgccgc gaggaacggc tgcgcgttgg
      541 acaggtccgg ctcgatggtc aggtcccggc cgagcagcgc gcccggcgtg acccgccaga
      601 cgttcggctc gccgcccgac tcgggggtgt ccacctgggc gcccaccgcg cgcagcatgt
      661 ccaccgtcat ccggatgtgc ggcagggagg gcagcgtggc gccggtgtgc cggacctcga
      721 cgccctggtt gaagcggggg cccgacagca gcagggcgct gacgaactgc gacgaggacg
      781 aggcgtcgac ctccaccggg ccgccgtcca gcgcgccgcc gccgtgcacc gtcagcggca
      841 gcgcgccccg gccgtcgtcg tcgatgcggg caccgagcac acgcagggcg tcgatgacgc
      901 cggtcagggg acgttcgtac gaacgtgggt cgccgtcgaa gcggacggga ccgtcggcga
      961 gggcggcgac cggcggcagg aagcgcatca ccgtgcccgc gttgccgacg tcgacggtgg
     1021 ccgggccgcg gagccccgtg gggagcacgc gccaggcctc gccggtcccg tcgggcccca
     1081 caccctcctc gatgcccacc cccatctcgc gcagggcgcc cgccatcagc agggtgtcgc
     1141 gggagcggag ggggcggcgc agccagccgg gctcggaagc cagggaggcc aggacgagag
     1201 cgcggttcgt gaccgacttg gaccccggca cgtggaccgt cgcgtcgacg gcctcgctcg
     1261 cgtgcggggc gggccagagg gcggtgtggg cggggttcgg ggccatgggc ccactgtata
     1321 agcagggcat gggcggggtg gtccggcgtg ggggccggcc gagggcccga gggcggcccg
     1381 gccggccggg tccgccggcg ttcagaggcc cagcagccag cgcccgccgc ccagcagggc
     1441 gcacaggctc accgcgtgga agaggaacag ccacaggccc gccgggacat gggtcaggcg
     1501 ggacagctgg tccgcgtccg agtcgccggc gccgccgcgg gaccgcttcg cctggagttc
     1561 gaaggccggg cgcactccgc cgagcagcag gaaccacacc accgcgtacg cgaacgccgc
     1621 ctgcacctgg gcatcggcca gccaggacac cagcaggaaa gcgccgccgg tgacgaccac
     1681 cgtcagcacc ccgtacgcgt tgcggatcat caccagcatc gcgaccagca gcaccgtggc
     1741 cagccacagc agcagcgtga tgcggccggc gccgagcagt gccgcgccgc ccaggcccag
     1801 cagcggggga gcggtgtagc cggaggccgc ggtgaggatc atgccgaggc cgtgcggctt
     1861 gccccggctg agggtcaggc cgctggtgtc ggagtgcagg cgtatgccgg tcagctgacg
     1921 accggtgagc agggcgacca gcccgtggcc gccctcgtgg gcgatggtga tggcgttgcg
     1981 cgagaggcgc cagagggtgt gcggcacgac cacggcgagc gcggcggcca tggtggcgat
     2041 caccacccac agatcggggt cggactgggt gccgacgagc cggtcccaga ggtcgggcag
     2101 cgcggtggcg gcggtgctgt ccatggtttc cggtggctcc ctcttgtcct aaggaatctg
     2161 gcagtgtggc acgtatgtgc ggacggtatg cggcgagtcg ccagcccgag gatctcgcag
     2221 gagtctttga gatcgagaag tgggagcccg aggagaccct cgagcccgac tacaacgtgg
     2281 cccccaccaa ggaggtccat gtggtcctgg accgtcctct gaaggacgtg ccggacccgc
     2341 gcccggttcg ccagctgcgc aaactcaggt gggggctggt cccgtcctgg tccaagaccc
     2401 ccgagggcgc cgcccggatg atcaacgcgc gggcggagac cgtccacgag aagccgtcgt
     2461 tccgccgcgc cttcgccacc cgccgctgca tcatccccgc cgacggctac tacgagtggg
     2521 tgaccggaca gcaggagcgc gaactggagg tcgaggggag gaggaagcgg ccccgcaagc
     2581 agccctactt cgtgctcccc gccgacggct cggtcttcgc gatggccggg ctgtacgagt
     2641 tctggcgcga ccgcacgctg ccggacgacc atccgcgggc ctggtgggcg acctgctcgg
     2701 tggtcaccac cgacgcggag acgaccccgc tggccgagtc ccccgcggag ggcccgcgga
     2761 cgctgtacga catccatccc cggatgccct gatgctcacc cgcgaccgct gggacgcctg
     2821 gctggacccg tcccgcacgg acgtcgagga cctgcgcccc ctgctcgccc cgcccccgcc
     2881 cggcctgatg cgcgcgtacc ccgtgtccac cgccgtgagc aacgtccgca acaacggccc
     2941 ggagctgctg aaggagctgg agggacccga ggagggcaca ctcttctgac gtgaccgagg
     3001 ggacgaaggt gacagacgtg actaccgagc ctgccgagaa cgacgggggc cccgagaacg
     3061 acgaaggccc tgggaacgac ggaagtaccg agaacgcccc ggtcgccgag accgtcgaca
     3121 ccgacgccgg tcccgcccgc atcacctggc accgggcgag gcggcccagg ctcgtcctcg
     3181 ccgtgagcca cggcgcgggc ggcggcatcg aggcgcggga tctgcgcgcg ctcgccgagg
     3241 tgctccccgg gcacggcgtc agcgtcgccc tcgtcgagca gccctggcgg gtggccggca
     3301 ggaaggtggc gcccgcgccg aagacgctcg acgtcggctg gcgcgggatc tggccggccg
     3361 tcgcgaaggc cggcctcccg gtgatctccg gcgggcgcag cgcgggcgcg cgggtggcct
     3421 gccgtaccgc cgtcgaactc ggcgcccacg ccgtcctcgc gctcagcttc ccgctccacc
     3481 cgcccggcag gcccgagagg tcccgggccg cggaactgct gggcgccggg gtgcccacgc
     3541 tcgtcgtcca gggcggcaac gaccccttcg gcaagcccgc ggagttcccc gaggggacgt
     3601 acgccctggt cgaggtgccc tacggcgatc acgggttcgc cgtgcccaag cgggccccgg
     3661 tcacccagga ccaggccctg gagacggtca ccgcggcggt cctcccgtgg gccgtgtcac
     3721 tcgggtgaac agcggggaat gttgcggggc gcagggctgt tgagccgggc agaagtgctg
     3781 aacacgcagc accgatgtcg tgggagagga agtccggcgc atgggttcga ccatctgccc
     3841 cagccgcacc gacctggact ggacggtgct gcacgcggcc aagaccgctc acattcgagc
     3901 ggcgggtggg acgggtagtc gtctatcctc cgattcgagt gggaccggtc tcggtcctgc
     3961 ccgcgatctt gaggaggtgg gtccggtcac cggtaccgac gcagggaccg acaacggcca
     4021 ggcggagctg cccgagggcc agggcacggg cgtggggacg gcagcggagt ccaccacgga
     4081 gcgcagcgcg cgcttcgagc gggacgcgct cgagttcctc gaccagatgt actcggcggc
     4141 cctgcgcatg acgcgcaacc cggcggacgc cgaggacctg gtgcaggaga cctacgccaa
     4201 ggcgtacgcg tccttccacc agttccgcga gggcaccaat ctcaaggcct ggctgtaccg
     4261 gatcctgacc aacaccttca tcaactcgta ccgcaagaag cagcgcgaac cccagcgcag
     4321 cgcggccgag gagatcgagg actggcagct ggcgcgcgcc gagtcgcaca tgtccacggg
     4381 tctgcgctcc gccgagtcgc aggcactgga ccatctgccc gactcggacg tgaaggcggc
     4441 ccttcaggcg atccccgagg aattccgcat cgccgtctac ctcgcggacg tagagggctt
     4501 tgcgtacaag gagatcgcgg acatcatggg gacacccatc ggtacggtga tgtcccggct
     4561 gcaccggggc cgccgtcaac tgcgcggcat gctcgaggac tacgcccgtg agcgcgggct
     4621 ggttccggca ggcgccgggg agtcgaacga agcgaaaggc tctgggtcat gagctgtgga
     4681 gagccgcacg agacggactg cggtgaggtc ctcgaccatc tctacgagtt tctcgacagt
     4741 gagatgccgg acatggaccg cgacaagttc aagcagcact tcaacgagtg ctcgccgtgc
     4801 ctggagaagt acgggctgga agaggccgtc aagaagctgg tcaagcgctg ctgcggccat
     4861 gacgacgtgc cgaccgacct gcgctcgaag gtcatgggcc ggatcgagct gatccgctcc
     4921 ggccaggccg tgcccgagca cgatgtgtcg gtcacccctc aggagtcctg acctccgccc
     4981 tgcctccgcg gaagtcctgc ctccgcggaa gtcctgcacc acgcagaagt tctgcaccac
     5041 gcggaagtcc tgcaccacgc agaagttctg cacccgcgta ggtcccacgt ctcccgagga
     5101 cgcaccgaca tcacccgaac gtgctaatcc gccggtgata cgcccgcgtc gccacccccc
     5161 gccaccctag gctccggagc ctggacgagg cgtggccggg ggagggcgac atggacggca
     5221 ttccggtacg ggcgcgggtg tacgtcggct gtgccgtcct cggcgccctg tgctgcctgt
     5281 tccccctgcc gtcggaccgc acgcgctggt ggccggtcct actgctcgcc gcgctgtacg
     5341 cgggcggtga gcgcgtcgcc cgccgccggt tcgccggcac cctctacccc gtcctgctgg
     5401 ccggggcttt tctgtttccg gctgccgccg ccgcgctcgt cccgctgccg ggcgcgctgc
     5461 tgtccccggt ggagcaccgg cccttcccgc tgcggcgcgt ctggcgggcc gcccggctgg
     5521 cgctcggcgt gtgggccgcg tcccgcgcgc acgaggcgct gggcggccgg gaggccgtcg
     5581 gggcgtccga cggccccgcc ctcctcctcc cggccgcggc cggcgtcctt gtcctctgcc
     5641 tggtgctcgc cgtcctggac ggcgggatcc tcgcgctggc cgaggggctg ccggcccggc
     5701 gcgcctggca cgggccgttc ctgcgctccc tggcacccgt aggggtgcac gggctcgccg
     5761 ggctgatgat ggccgtcctg tggcacagcc cctacgggcc ggtcgccgcg ctgctcgtgc
     5821 tgttcccgat gggtgtgtcc tggtgggtgt tcgcccagta ccaccgggag cgcgccgccc
     5881 accaggcgac gatccgggcg ctggtgcagg ccgtcgacat caaggacggc tacacccgcg
     5941 ggcacagcga acgcgtcggc caggcctccc tgctgatcgc ccgtgagctg gggatggacg
     6001 agggccgggt cgaggtgatc cgcttcgccg ggatcctgca cgacgtcggc aagctcggcg
     6061 tgcccacccg gctgctccgc aagaaaggcc cgctgacgcc cgaggaacgg cgcgtgatcg
     6121 aactgcaccc cgagtacggg cacgagatca cccggggcat ctccttcctc ggcgaggccc
     6181 gctcggcgat cctccaccac cacgagcggc tggacggcag cggctacccc tacgggctgg
     6241 tcggcagtca gattccggaa cccgcgcgcg tggtggcggt cgccgacgcc ttcgacgcga
     6301 tgacctcgac ccgctcctac agccgggccc gccccgtgcc ggtggcgctg gaggaactcc
     6361 agcggtgcgc gggggcccac ttcgaccccc gcatggtcac cgcgctgacc cgtgtgatca
     6421 cccgggacgg ctggcatccg atcgtcaccg ccgacgagcc ccgcctgccg gcacagtccc
     6481 cggccgaccc cgttcccgag cggccggggg cccggcggtg agtggccgcc gcagggcggt
     6541 gcgggcaggc gggctcctga gcgtcctgca cggcgccgcc gggctgctcg tcgtcgcgtc
     6601 gctgttcgtc gtcctccgct cggggctggc ggagcggccc gtcgcgctcg ccttcggggt
     6661 gctgatggcc gtcggcgagc tgacccggtg gagcggaccc ggactgcgcg aggccgcgcc
     6721 gctcggttcc gccgcctcgc tgtcgtacgc gctgctcggg gagcatgccg ggcacgccac
     6781 gcaccacggg gtggcccagg tcgtcgccgt cgtggtggcc gcctcgctgc tgggcagcgt
     6841 gccgcacatc gcgcgcgggc aggggcccgt cctggaccac ctggtccggc gcgtgctggc
     6901 cgtcggcttc gccgccgtct gcttccagcc gctctacaac cacggggtgt tcgcccgctg
     6961 gaccggcccg gcctacgcgc tgctgctgct cgcgctgctc gtcctcaccg cgctgtgcga
     7021 cgccgtcgtg gccgccgcgc tcgcgcactc ccgtacgggc tggccgttcg ccccgctgct
     7081 ccgcgacgag ctgcggtccg taccggggct cgggtcggcg gtggccgcga cgggcgcggt
     7141 gatggcgctg gcggtggccg tcgtcggcct gtgggcgctg ccggtgttct cggtgccgtt
     7201 gctgctcacc cagctgtccc tgcgccggta cgccgccgtc cgcgccacct accggcagac
     7261 catcgcctcc ctggcccgcg ccaccgagat agccgggtac accccggccg ggcacgcccg
     7321 ccgggtcgcc gcgctctgcc aggcggtcgg ccgggacctc ggcctcacgg agccggagct
     7381 gaccgtgctg gagtacgcgg ccctgatgca cgacatcggg cagctcagcc tcgtcgaccc
     7441 ggtcccggcc ggggccacgg ccgggctgcc cccggccgag cagcggcgca tcgccctgct
     7501 cggtggggcc gtggtccgcc agaccggggc gagtgcgcag gtcgccgcgg tggtggagtg
     7561 ccaggccgac ccctacccgg agcagccgac ggccgcgcgg atcgtgcggg tggtcaacgc
     7621 ctacgaggag aaggtgcgcg acgccggccc cggcgggccg ctcacggcgc tggaggaact
     7681 caggctgggc acgggcgggg agtacgcccc cgaggtggtg gaagccctgg ccagggtgct
     7741 gtcgcgggac tgtcttaccc tgcccgcggg tgggtaaccc atgggtaatg agcgcccttc
     7801 cgaccacacg tggttggatg cgagggagag agtgtccggg ggcactggcc agcccacaga
     7861 acggaactgg caggcgggaa tcgtgaggat cttcggcaag ggacggcacc ggccctccgc
     7921 ctcctggcgg caggccaccg atcgcgcctt cacgctgatc ggcgacggcc ggtacgagga
     7981 cgcgggcgcg ctgctgaccc gtgccgccga tctcgagccc tggctgtcgg agtcctggtt
     8041 caacctcgcc ctcctgcaca agttccggca cgactgggag caggcccgca ccgccgggct
     8101 ccgggcggtc gccctgctcg accgcgagac cggcgccccc gactggtgga acgtcggcat
     8161 cgccgccacc gccctgcagg actggccgct ggcccggcgc tcctggcagg cctacgggct
     8221 gcacgtcccg ggcggtccca ccgccgccgg cgagcccctc ggcatggacc tgggcagcgc
     8281 ggccgtacgg ctgtcgcccg agggggaggc cgaggtggtg tgggggcggc ggctggaccc
     8341 cgcgcggata gaggtgctgt cgatcccgct gccgtcgtcc gggcggcgct ggggcgaggt
     8401 cgtcctgcac gacggggtgc cgcacggcga gcgcaccacc tcggtggggc actcctaccc
     8461 cgtcttcgac gagatcgagc tgtgggcgcc ctcgccggtg ccgacctggg tggtcctgct
     8521 ggaggcggcc acggagacgg accgtgacgc gctggagcag ctggccgccg acgcgggctt
     8581 cgccgccgag gactggtcgt cctccgtacg gctgctgtgc cggatgtgct ccgagtcgcg
     8641 gatgccgtcc gacgaggggg acggcgagca cctcgacccg cacgatcaca gtgagcctgg
     8701 gcaccccggg ccgctcggcc accggaccga cgggcagctg tgggtgcccg agcgggagtg
     8761 cggggtggcc gcgccggcct cgctggtgag ggggctgctg gacgggtggg tcgcggacag
     8821 cccggactcc cgggactggc gagacctgga agaggtctgc taaggcctgt cgtggctcgg
     8881 tcgcgtgccg gtgcgtggct ggtcgcgccc cgcggcggag ccgcatctcg atacggcccc
     8941 gcgcgccgtg cgggacgctc cacgtaccct gtatccgcat cacacccccc gctttttctg
     9001 aggaaggcat acgtcggtca tggcgcagca ggacaccgat cagcagcacg cgggagtgct
     9061 ccccgtggac gacgagggct tcgtcatcga caccggggag acggaggagc gcgagcaggc
     9121 ctggcgtcgg gccgggaccg cgcggcccat caccgtcgtg gggaacccgg tgctgcacaa
     9181 ggagtgcaag gacgtcaccg agttcggcga ggagctccag cagctggtcg cggacatgtt
     9241 cgcctcgcag cacgccgccg agggcgtggg cctggccgcc aaccagatcg gcgtcgatct
     9301 gaaggtgttc gtctacgact gcccggacga cgagggcgcc cggcacaccg gcgtggtctg
     9361 caaccccaag ctggtggagc tgcccacgga gaggcgccgg ctggacgaca gcaacgaggg
     9421 ctgtctgtcg gtgcccaccg cgtacgcgcc gctggctcgg cccgactacg ccgaggtgac
     9481 cggtcaggac gagaagggca acccggtcag ggtgcgcggc acgggatact tcgctcggtg
     9541 tttgcagcac gagacggatc acctctacgg gtacctctac atcgaccgtc tctccaagcg
     9601 tgaacgcaag gaagcgctgc ggcagatggc cgagaacgag cctcgctacg ccgtggtccc
     9661 caacgactga gccgtcctcc ttcccacgac gcccggcccg cgatcagcgg cggccgggcg
     9721 tcgttcgtgt gtccgacgca cgttcgatcg cttatgcaca tctgctgatc cataacaagt
     9781 cacgcaaggg gggattctcg gcgtgttggg gtagtgaatg aagcaaatcc gttcccagaa
     9841 cggtcagttg tggtgctgaa taggaagtgc ggggatacgc aacggcgcac gcccggcacg
     9901 gcgggagggg tgtgtaccaa ctggcggctg agaggggttg ttcgtgccag ctttcccata
     9961 cagcaccaca taccgcacca cataccgcac cgcggggacc gtgaccgcgg tcgcggttcc
    10021 cgcatcgctc tctctcccgg tcatcgaggc ggtgtttccc aggcaactgc atccgtattg
    10081 gcctcagttg caggagaaca cgcgtgcgtg gctgctcgaa aagcggctca tgccggcgga
    10141 caaggtcgcg gaatatgccg acggcctgtg ctacaccgac ctgatggcgg gctactacct
    10201 cggcgcaccc gacgaggtca tgcaggccat cgccgactac agcgcgtggt tcttcgtctg
    10261 ggacgaccgg cacgaccgtg acgtcgtgca cggccgggca gccgcctggc ggcagttgag
    10321 gcgccgcctg cacgtggccc tcgactcccc ggacgagcac ctgctacacg aggatccgct
    10381 ggtcgccgga ctcgcggaca gtgtgggccg gctgtactcc ttcctccccg cgacctggag
    10441 cgagcggttc gcccgccact tccacgaggt gatcgaggcg tacgaccggg aattccacaa
    10501 ccggatggac gggcgcatac cgggcgtcga ggagtatctg gtcctgcgtc ggctcacctt
    10561 cgcgcactgg atctggacgg atctgctgga gccgagtgcg gggtgcgaac tcccggacgc
    10621 cgtacggaaa cacccggcct atcggcgtgc ggctctgctg agtcaggaat tcgccgcctg
    10681 gtacaacgac ctctgttcgc tcccgaagga aatagcgggc gacgaggtgc acaatctcgg
    10741 aatcagtctc atcgcccatg aggggctgac cctcgaagag gcggtcgagg aaatcaggcg
    10801 gcgcgtcgag gactgcatat ccgaattcct cgtcacggag aaggacgtgc tgaggctggc
    10861 cgacaggctc accgacggga cggtccacgg aaaggaactc ggcgccgccg tacgggcctg
    10921 tctcgagaac atgaggaact ggttcagttc cgtctactgg ttccaccacg agtccggccg
    10981 ctacatggtc gacagctggg acgaccgttc cacgcccccg tacgtcaaca acgaagcggc
    11041 aggtgagaaa tgaccgtcga gtccgtcaat cccgtgacgc ccgtggcacc ggaactgcgt
    11101 gagccgccac tggccggtgg tggggttccg cttctcggcc acggctggaa gctcgcccgc
    11161 gacccgctgg ccttcatgag ccagctgcgc gaccacggcg acatcgtccg catcaagctc
    11221 ggaccgaaga cggtgtacgc cgtcaccacg ccggccctga ccggggccat ggccctcagc
    11281 cccgactaca tcatcgccgg accgctgtgg gagtccctgg aagggctgct cggcaaggag
    11341 ggcgtggcca ccgccaacgg cccgctccac cggcgccagc ggcgcaccat ccagcccgcg
    11401 ttccggctcg acgccatccc cgcctacggg ccgatcatgg aggaggagac gcgcgcgctc
    11461 gtcgagcggt ggcagggcgg tgagacgatc gactgcacct cggaatcgtt ccggatagcg
    11521 gtgcgggtgg cggcccgctg tctgctgcgc gggcagttca tggacgagag ggccgagcgg
    11581 ctgtgcgtcg cgctcgccag cgtcttccaa ggtatgtacc accggatggt ggtgccgctc
    11641 ggaccgctct acaggctgcc gcttccggcc aaccgcgaat tcaaccgggc cctggccgat
    11701 ttacatctcc tggtcgacga gatcgtcgcc gaacgccggg catcaggtca aaagccggac
    11761 gatttgctga cggcattgct ggaagcgaag gacgacaatg gcgacccgat cggggaacag
    11821 gagatccacg accaggtcgt cgcgatcctc acccccggca gcgaaaccat cgcttccacg
    11881 atcatgtcgc tgctcctggt tctcgcggac catccggaac aggcggacaa ggtgtgctcc
    11941 gaggtacggg ctgtcaccgg aggacggccc gtcgcattcg acgacgtgcg caagctcacg
    12001 cacacgaaca acgtcgtcat cgaggccatg cgtttgcgcc cggccgtatg gatattgacg
    12061 cggcgggcag tcgccgacac cgaactcggt ggctatcgca ttccggccgg ggccgacatc
    12121 gtgtacagcc cgtacgcgat ccagcgcgac ccgcggtcct acgagcggca cctcgagttc
    12181 gaccccgacc gctggcttcc ggagcggtcg aaggacatcc cgaagtacgc gatgcggccg
    12241 ttcagcgtgg gcaaccgcaa gtgccccagc gaccacttct cgatggccct gctcacgctg
    12301 gtcacggcgg tgctcgcgga cggcttccgg ttcgagcagg tccccggctc ggtcgacgag
    12361 acccgggtgg gcatcacgct gcgtccgcaa cggctgcggc tcaagcccgt cccgcggtga
    12421 gaccgtcccc gccgccggcg tgcgttcagg cggcctccgg gccccggaac gtacgccggt
    12481 aggcgttcgg ggtggtgccc agcacccgca cgaactggtg ccgcagcgcg cccgccgtgc
    12541 cgaacccggt ccgccaggcg atcgcgtcca ccgtctcgtc ggacgcctcc agcagatgct
    12601 gggcgagcag tacccgctgg cgcaggagcc agcggtaggg cgtcgtgccg gtctcctgct
    12661 ggaagcggcg ggcgaaggtg cgcggcgcca tgtgggcgcg ggcggcgagc tgctcgacgg
    12721 tgacctcctg ggcgaggtgc tgctccatcc acgcgagcac ctcgcccacg gtgtcgcagg
    12781 aagagcgcgg cagcggccgc tggatgtact gggcctggcc gccgtcccgg tgcggcggta
    12841 cgaccatccg ccgggcgatc ccgttggcga cctcgggccc ctgctccttg cgcacgaggt
    12901 gcaggcaggc gtcgatgccg gcggccgtgc cggccgaggt gatcaccggg tcctcgtcga
    12961 cgtagagcac gtcgggttcg acggtcgtgc gcgggtactc gcgggcgagc tgttccgcgt
    13021 gccgccagtg caccgcgcag cgccgcccgt ccaggagccc cgccgcggcc agcacgaacg
    13081 ccccggagca cacgctcagc acccgggtcc cgcgctccac cgcccggcgc agcgcgtcga
    13141 gcagctcggg cgggaactcc cgggccgtgt acgtgtcgcc ggccggtacg gcgatcaggt
    13201 cggcgctctc cagccgttcg agcccgtgtg acgtgctcat cgtgaagccc gggtgcggtg
    13261 tggacagggt cggcccctcg gccgaggcga cggcgaagtc gtagaccggc agcccctcgt
    13321 cgctgcggtc gatgccgaac acctcgcaga cgactccgag ttcgaaggga tgcacgccgt
    13381 cgaggaggat cgcggccacg ttcttcagca tgccgccagt gtgcaccgga agtggcagta
    13441 atttgaaggt gtgcggcagt cctgccactg tcatgagtgt cacggacgca tgatgcttac
    13501 ctcatgaacg cactcgccga agctctcacg gtcctggtcg tcttcctcgt cctcgcgggt
    13561 cgcgctcgtg gggctggccc acgaacgccg gatcgaccgc cgactgcgcg aggcgcggac
    13621 tcagaagtcc tcgtccaggt cgacggtgcc ctccaccgcg acctggtacg ccgacggacg
    13681 gcgctcgaag aagttggtca gctcctgaac gccctgcaac tccatgaagg agaacgggtt
    13741 ctccgagccg tacaccgggg cgaaaccgag gcggctcagc cgctggtcgg cgacgcactc
    13801 caggtactgg cgcatcgagt cggtgttcat gcccggcagt ccgtccccgc acaggtcgcg
    13861 cgcgaactgc agctcggcct cgacggcctc ccgcagcatg tcggtgacct gctcctggag
    13921 ccggtcgtcg aacagctccg gctcctcctt gcggacggtg tcgacgacct cgaacgcgaa
    13981 ggacatgtgc atggtctcgt cacggaacac ccagttggtg ccggtggcga ggccgtgcag
    14041 caggccccgg ccgcggaacc agtagacgta cgcgaaggcg ccgtagaaga acaggccctc
    14101 gatgcacgcg gcgaagcaga tcaggttgag caggaagcgg cgacggtcgg acatcgactc
    14161 cagccggtcc agcttctcca ccgagtccat ccagcggaag cagaactcgg ccttctcacg
    14221 aatggagggg atgctctcga ccgcgtcgaa ggcggcggcg cggtcctccg ggtcggggag
    14281 gtaggtgtcc agcagggtca gatagaactg gacgtgcacc gcctcctcga agagctgccg
    14341 gctcaggtag agccgcgcct cgggggagtt gatgtgcttg tacagcgtca gcaccaggtt
    14401 gttcgagacg atcgagtcgc ccgtcgcgaa gaacgcgacc agccggccga tcagatgctg
    14461 ctcggcgggc gtcagcttcg cgaggtcggt cacgtccgag tggaggtcga cctcctcgac
    14521 ggtccaggtg ttcttgatgg cgtcccggta gcgctcgtag aagtcggggt agcgcatggg
    14581 acgcagggtc agctcgaagc ccgggtcgag gagattctgg ttacgggtgg tcattactgg
    14641 caggcctcgc aggactcggg gttctcaagg gagcaggcga cggcctcttc gggagccggc
    14701 tgccgcacgg ggatgggggc ttgggcctgg gcggcgcggg cgatgcgggt cgccgggcgc
    14761 gagcgcaggt agtacgtcgt cttgagcccc gacttccagg cataggcgta catcgaggag
    14821 agcttgccga tggtcggcgt ctccaggaag aggttcaggg actgcgcctg gtccagatac
    14881 ggggtccgcg cggcggccat gtcgatcagc ccgcgctgcg ggatctccca cgccgtgcgg
    14941 tacagcgccc gtacgtcctc ggggatccag gtgaacccct ggaccgagcc gctcgcctcg
    15001 cgcagcgcct cgcgggtccg ggcgtcccag acgcccagct ccttgagttc ccgcaccagg
    15061 taggagttga cctgaaggaa ctcgccggac agcgtctcgc gcttgaacag gttggacacc
    15121 tgcggctcga tgcactcgta cacaccggcg atcgacgcga tggtggcggt cggcgcgatg
    15181 gccaggagca gcgagttgcg caggccggtc gccgcgatcc gctcgcgcag cgccgcccag
    15241 cgctccggcc aggtgaactc gacgccgtag tggtcggggt gcagcacgcc acgtgcggta
    15301 cgggtcttcg cccaggcggg cagcgggccg ttgcgctcgg cgaggtccgc ggaggcctcg
    15361 tacgcggcga gcatgatccg ctcggcgatc cgggtggaga gcgccttggc ctcgggcgag
    15421 tcgaagggca gccgcagctt gaagaagacg tcctggaggc ccatcgcgcc cagaccgacc
    15481 gggcgccagc gggagttgga gcggcccgcc tgctcggtcg gatagaagtt gatgtcgacg
    15541 acccggtcca ggaaggtgac ggcggtgcgg acggtctcgt ccagccgctc ccagtcgatg
    15601 acctcggtgg ccccggggtc cgtgtcgacg aacgcgccga ggttcaccga ccccaggttg
    15661 cagaccgccg tctcaccgtc gtcggtgacc tccaggatct ccgtgcacag gttcgaggag
    15721 tggaccacat ggcccggctc ggcggtctgg ttggcggtgc ggttggcggc gtccttgaag
    15781 gtcatccagc cgttgccggt ctgcgcgagg gtgcgcatca tgcggccgta cagctcacgc
    15841 gccgggatgg tcttcctggc cagcccctcg gcctccgccg cgcggtaggc cgcgtcgaac
    15901 tccgcgcccc acaggtcgac cagctcgggc acgtcggccg gggagaacag ggaccactgc
    15961 ccgtcgtcgt cgacccggcg catgaactcg tccggcaccc agtgcgccag gttgaggttg
    16021 tgcgtacggc gggcgtcctc gccggtgttg tcgcgcagct ccaggaactc ctcgatgtcg
    16081 gagtgccagg tctccaggta caccgcggcc gcgcccttgc gccggcgccc tggttcacgg
    16141 cggcgaccga ggcgtccagg gtcttcagga acggcacgat gccgttggag tgcccgttgg
    16201 tgccgcggat gagcgacccg cgggaacgga tgcggctgta cgacagaccg atgccgccgg
    16261 cgtgcttgga gaggcgggcg acctgctggt agcggtcgta gatggagtcc agctcgtcca
    16321 gcggggagtc gaggaggtag caggacgaca tctgcgggtg gcgggtgccg gagttgaaca
    16381 gggtggggga ggaggggagg tagtccaggc ggctcatcag cgtgtagagc gcggcgacct
    16441 cgtcgacgga cctcgtcgtg tcgtcctcgg ccaggccgct cgccacgcgc agcaggaagt
    16501 gctggggcgt ctcgacgacc ttgcgggtga tcgggtggcg cagcaggtag cggctgtgca
    16561 gggtgcgcag gccgaagtag ccgaagcggt cgtcggcgcc cgtgtcgacc agcgcgtcga
    16621 gccgggccgc gtgcagccgt acgaactcgg cggtgcggtc ggcgatcagg ccctcgcggt
    16681 ggccgacggc gacggactcg gtgaaggtgg tgacgccctg ggaggcggcc tccgcgcgga
    16741 tcccgatcgt gagcagccgg gcggccagtt gggagtaggc gggatcctcg gagatcagac
    16801 cggcggccgc ctcggtggcc agctcgcgca gctccgactc gtccgcccgc gcggaccggc
    16861 cccgcagggc ggcggcggcg acccggccgg ggtcggcgtc gggaaggtcg gcggtcagct
    16921 cggtcagcgt ccgcagcagt gcggttccgg gaccgtcggt cttcggggct gctgaaaccg
    16981 gttcggctgg cgcgatggtc acgtggggct ctccctcgct cggcgggggc cttgcggagg
    17041 gcagcgggca gcacacgagc gcggggcgcg ccgcgtccac cggcccattc cgcgaggccc
    17101 ggacgtccaa gcacccgagc cggacggatc gggtgcgctg ccggcaggtg ctcggactga
    17161 ccatgcgtgc gcgaaagcag aggaacgcac gcaagtacac cgttgcggga cagttccgga
    17221 ttcgcaccgg attcccctgc ggcggcagcg agcacgagca tacatcttgt gccgggctgc
    17281 cgcgcgaccc ccagatgttg tgtcggaccg gcttcgcagc gtcaactcgt ggggcgatgg
    17341 gcccagtcct gcgagcggga gcgcgtacgg cggcgggccg ccggggcgag gtgcctcggc
    17401 ggcccgctgt ggccttgggt ggggagacgt tcccctcgcg ctagtgcccc gcccccgccg
    17461 tcgccggggg cagctccacc tggacgcccg ggtcgccggc gtccgccgtg tagtccgacg
    17521 gggacgtctc gtcgacaccc tccggggcct tcagcgcctt catgacgaag gtcagcacca
    17581 ccgtcaccac cacgttcagc acgaacgccg tgaggccgat gtagccgatc tcgccgatgc
    17641 cggggatctc cttcgacgag ccgccgaagt gcttctgggt cggggaggcg acgccgtacg
    17701 ccgccaccgt gccgtagacc atgccgaccg cccagccggc cagcagcgcc cagcggtgga
    17761 accagcgggt gaacaggccg ccgaccaggg ccgggaaggt ctggaggatc cagatgccgc
    17821 ccagcagctg gaagttgatg gcgaccgtct tgtccatggt gaggacgaag gccagcgcgc
    17881 ccaccttcac caggagcgag accagtttgg agacgcgggt ctcctccctg ggcgtggcgt
    17941 ccggcttgat gaagtccttg tagatgttgc gggtgaagag gttcgccgcc gcgatggaca
    18001 tgatcgccgc cggcaccagc gcgccgatgc cgatcgccgc gaacgccacg cccgcgaacc
    18061 agtccgggaa catgtcctcg aacaactgcg ggatcgccag ctgcccgttg gagaccttca
    18121 ccccggccgc gatcgccatg aagcccagca gggcgagcag accgagcatg agggagtaca
    18181 gcggcaggat cgtggtgttg cggcggatca cgtcacggct gcgcgaggac agcgtcgcgg
    18241 tgatcgagtg cgggtacatg aacagcgcca gcgcggaccc caacgccagc gtggcgtagg
    18301 tccactggcc cgcctcgctc ggcaccagcg aaccgcgtgg cgcgcccgtc gccgggttgg
    18361 tctgcgagaa ggcgtcgccc gccttcgcga agatgtcgtc gaacccgccc agcttgatgg
    18421 ggatgtagat gatcgccacc gcgatgacga tgtagatcag cgtgtccttc acgaacgcga
    18481 tcagcgcggg cgcccgcagg cccgaggagt aggtgtaggc cgccagcacg ccgaaggcga
    18541 tcagcagcgg caggtccttg acgaaccagt tggtgtcctc accgccgccg acacccatca
    18601 cgtccagcac ggcctggatg ccgaccagtt gaagcgcgat gtacggcatg gtggccagga
    18661 tgccggtgac ggccacggcc agggacaggc ccttggagcc gaaccggccg cgcacgaagt
    18721 ccgaggtcgt cacgtacccg tgcttgtgcg acaccgacca caggcgcggc aggaacgtga
    18781 agatcagcgg gtagacgagg atcgtgtacg gcaccgcgaa gaagcccgcc gcgccggccg
    18841 cgtagatcgc cgccgggacc gccacgaacg tataggccgt gtacaggtcg ccgccgagca
    18901 ggaaccaggt gacccaggtg ccgaacgacc ggccgcccag gccccattcg tcgagactgt
    18961 gctcgtcgtc ggccctgcgc cagcgcgcgg ccaggaagcc catgacggtg acggccagga
    19021 agaagaagat gaagacggcg agtgccacgc cgttcacgcc gccgttcact tcgccgcacc
    19081 cccgccctgg ttcctacggc cgcgctggtc gacctgccac agcttgtacg cgaccaccgt
    19141 gagcagggtg gagagcagca cccacagcat ctggtaccag tagaagaacg ggatgccgat
    19201 gaacgcgggg tcggtcttcg cgtacgaacc gacccacagc atcgccacga agggcgcgaa
    19261 caggcagagg gcgatgacga cgcgcaaagg cgtcaccacc ggccctccgt tgacttctgg
    19321 ggcttctgac atcgggcggc tccgtcccct cgcagatcat gtgcaacgcg cacgaaatgt
    19381 aggtgacgga taaagccaag cggaagacct cgtccgcata tcggtcccgt aggtcgacgg
    19441 ggttgccggt ttactccacg ggttgctcca cgggccgctt cagccgcacg acgctgtgtt
    19501 gttccggggg gtgaccccgg acccccagcc gccctgctgg acggtacgcc tagtccacgg
    19561 gccgcttcag ccgcgcgacg aacttgtacc ggtccccgcg gtacaccgac cgcacccact
    19621 ccaccgggag accctccctg tccacggagt ggcgggacag catcagcatc ggcagaccga
    19681 cgtccgtgcc gaggaggccg gcctcgcgcg gggtggccag ggaggtctcg atggtctcct
    19741 cggcctcggc gaggtggacg ccgtagacct cggcgagcgc ggtgtagagg gacgtgtact
    19801 tcaccagtga cctgcgcagg gccgggaagc gcttggccga gaggtgggtg gtctcgatgg
    19861 ccatcggctc gccgttggcc atgcgcagcc gctcgatgcg cagcacacgg ccgcccgcgg
    19921 tgatgtccag cagcccggcg agccggtcgt cggccgtgat gtagccgatg tcgaggagct
    19981 gcgaggtggg ttcgaggccc tgcgcgcgca tgtcctcggt gtacgaggtg agttgcagcg
    20041 cctgggagac cttcggcttg gccacgaagg tgcccttgcc ctggatgcgc tccagccggc
    20101 cctcgacgac cagctcctgg agcgcctggc gcacggtggt gcgcgaggtg tcgaactcgg
    20161 ccgccagggt gcgctcgggc ggcaccgggg tgccgggcga ctgcgtctcc gtcatgtcga
    20221 ggagatgctt cttcaggcgg tagtacttgg gcacgcgcgc ggtacggacg gtcgccccac
    20281 cctcgttctc cgcactgctg acgtcggtgc tcatgtcctg ccttcccggc tccggggtgc
    20341 cgaagcggcc gacagtcccg tcggccgcgg ctcacatcgt ggcacgggtt cgtcggcggg
    20401 gtatccagtg cggtgacctc gcgcggtccg tgatctcttc tgtatacctc cgggacctcc
    20461 gttggtctag tccaacatgt cggccggggt cgattggttc acttccccgc gagaggccga
    20521 tacgtggccc gcgaattgaa aagtccctgc atatcgcggt cccgtaacgg acgactcaac
    20581 cccggttgaa cacccttgac agcccaattg gtctgagcca agctccggct tactggtcta
    20641 caccattggt ccaggtcctg gccccacgga cggtacgcgt tgacgctcga ccgcggcggg
    20701 gaggcagggg ggtttgtggg atccctgagg agggttggcg tgaagcgcaa gctgatagcc
    20761 gcgatcggta tcgcgggcat gatggtctcc atcgcggcgt gcggggacga caaggacagc
    20821 ggtggttcgg acaagggcac cgacgccaag gaactgacgg tctggctgac cgtcgacgcg
    20881 cagaacaact ggcccgaact ggtgaaggcc gcggacgcgg cggtgcagaa gaagcacccc
    20941 ggcgtgaaga tcacccacga gtactacggc tggcccgaca agaacgccaa gctcgacgcg
    21001 gttctcgcca ccgacaaggt gcccgacgtg gtcgagatgg gcaacaccga gat
//
